CN114126643A - 包含溶菌酶的广谱抗菌药物制剂及其使用方法 - Google Patents

包含溶菌酶的广谱抗菌药物制剂及其使用方法 Download PDF

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Publication number
CN114126643A
CN114126643A CN202080048142.9A CN202080048142A CN114126643A CN 114126643 A CN114126643 A CN 114126643A CN 202080048142 A CN202080048142 A CN 202080048142A CN 114126643 A CN114126643 A CN 114126643A
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CN
China
Prior art keywords
formulation
lysozyme
pharmaceutical formulation
weight
pharmaceutical
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Pending
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CN202080048142.9A
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English (en)
Chinese (zh)
Inventor
第欧根尼·艾巴尔-巴蒂斯塔
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Aibar Ecological Technology Co ltd
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Aibar Ecological Technology Co ltd
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Publication of CN114126643A publication Critical patent/CN114126643A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202080048142.9A 2019-05-28 2020-05-28 包含溶菌酶的广谱抗菌药物制剂及其使用方法 Pending CN114126643A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962853215P 2019-05-28 2019-05-28
US62/853,215 2019-05-28
PCT/IB2020/055083 WO2020240472A1 (en) 2019-05-28 2020-05-28 Wide-spectrum antibacterial pharmaceutical formulations comprising lysozyme and methods of using the same

Publications (1)

Publication Number Publication Date
CN114126643A true CN114126643A (zh) 2022-03-01

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CN202080048142.9A Pending CN114126643A (zh) 2019-05-28 2020-05-28 包含溶菌酶的广谱抗菌药物制剂及其使用方法

Country Status (12)

Country Link
US (3) US20200376094A1 (cg-RX-API-DMAC10.html)
EP (1) EP3976093A4 (cg-RX-API-DMAC10.html)
JP (3) JP7768769B2 (cg-RX-API-DMAC10.html)
CN (1) CN114126643A (cg-RX-API-DMAC10.html)
AR (1) AR119031A1 (cg-RX-API-DMAC10.html)
BR (1) BR112021024001A2 (cg-RX-API-DMAC10.html)
CA (1) CA3145530A1 (cg-RX-API-DMAC10.html)
CO (1) CO2021017958A2 (cg-RX-API-DMAC10.html)
IL (1) IL288531A (cg-RX-API-DMAC10.html)
MX (1) MX2021014634A (cg-RX-API-DMAC10.html)
TW (1) TW202110474A (cg-RX-API-DMAC10.html)
WO (1) WO2020240472A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112135625B (zh) * 2020-04-27 2021-07-06 广州新创忆药物临床研究有限公司 一种预防或治疗covid-19新冠肺炎的药物及其应用
WO2023133412A2 (en) * 2022-01-05 2023-07-13 Prophase Labs, Inc. Compositions having synergistic anti-viral action and methods for treating coronavirus
CN114503981A (zh) * 2022-01-07 2022-05-17 上海膜益信息科技有限公司 一种不分层防霉液及其制备方法和应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1557485A (zh) * 2004-01-30 2004-12-29 大连帝恩生物工程有限公司 基因重组人溶菌酶在消除病原微生物感染炎症上的应用
UA48016U (ru) * 2010-01-25 2010-02-25 Илона Васильевна Ковач Способ профилактики кариеса зубов у детей 3-6 лет
UA68612U (ru) * 2012-02-07 2012-03-26 Дмитрий Викторович Дудар Способ лечения хронического рецидивирующего афтозного стоматита у больных целиакией
CN107899006A (zh) * 2017-11-28 2018-04-13 四川清舒乐科技有限公司 冲洗鼻腔的药物组合物及其制备方法

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Publication number Priority date Publication date Assignee Title
DK501686A (da) * 1986-10-20 1988-04-21 Otto Melchior Poulsen Enzymholdigt, baktericidt middel samt tandplejemidler og saarbehandlingsmidler, som indeholder det
ES2369670T3 (es) * 2004-04-08 2011-12-02 Dermcare-Vet Pty Ltd Composiciones antimicrobianas y métodos para su uso.
CN1583170A (zh) * 2004-06-10 2005-02-23 安米 用于抗病毒抗耐药菌的人溶菌酶药物及其制法
US20080095754A1 (en) * 2006-10-18 2008-04-24 Burke Susan E Ophthalmic compositions comprising diglycine
EP2207893B1 (en) * 2007-10-19 2011-12-28 Becton, Dickinson and Company Methods for the detection of beta-lactamases
WO2010036945A2 (en) * 2008-09-26 2010-04-01 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
CN105611909B (zh) * 2013-03-12 2020-09-15 普莱玛疗法公司 包含螯合剂和碱的牙用组合物
ES2834950T3 (es) * 2017-02-28 2021-06-21 Prec Group Limited Bifidobacterium longum capaz de modular beneficiosamente la respuesta inmunitaria a la infección por virus respiratorio
WO2019018368A1 (en) * 2017-07-17 2019-01-24 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. ANTIBACTERIAL METHODS AND ASSOCIATED KITS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1557485A (zh) * 2004-01-30 2004-12-29 大连帝恩生物工程有限公司 基因重组人溶菌酶在消除病原微生物感染炎症上的应用
UA48016U (ru) * 2010-01-25 2010-02-25 Илона Васильевна Ковач Способ профилактики кариеса зубов у детей 3-6 лет
UA68612U (ru) * 2012-02-07 2012-03-26 Дмитрий Викторович Дудар Способ лечения хронического рецидивирующего афтозного стоматита у больных целиакией
CN107899006A (zh) * 2017-11-28 2018-04-13 四川清舒乐科技有限公司 冲洗鼻腔的药物组合物及其制备方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KO KY等: "Ethylenediaminetetraacetate and lysozyme improves antimicrobial activities of ovotransferrin against Escherichia coli O157:H7", POULT SCI, pages 406 - 414 *
赵电波等: "天然生物防腐剂溶菌酶的改性研究进展", 中国食品添加剂, no. 05, pages 200 - 204 *

Also Published As

Publication number Publication date
US20240066105A1 (en) 2024-02-29
EP3976093A1 (en) 2022-04-06
AR119031A1 (es) 2021-11-17
CA3145530A1 (en) 2020-12-03
BR112021024001A2 (pt) 2022-01-25
CO2021017958A2 (es) 2022-01-17
US20220362354A1 (en) 2022-11-17
MX2021014634A (es) 2022-07-04
IL288531A (en) 2022-01-01
JP2022534776A (ja) 2022-08-03
JP2025038034A (ja) 2025-03-18
WO2020240472A1 (en) 2020-12-03
EP3976093A4 (en) 2023-07-05
JP2026021451A (ja) 2026-02-10
JP7768769B2 (ja) 2025-11-12
US20200376094A1 (en) 2020-12-03
TW202110474A (zh) 2021-03-16

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