CN1140596A - Ointment for treating burn and scald and promoting tissue regeneration - Google Patents
Ointment for treating burn and scald and promoting tissue regeneration Download PDFInfo
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- CN1140596A CN1140596A CN 95108098 CN95108098A CN1140596A CN 1140596 A CN1140596 A CN 1140596A CN 95108098 CN95108098 CN 95108098 CN 95108098 A CN95108098 A CN 95108098A CN 1140596 A CN1140596 A CN 1140596A
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Abstract
The said ointment as Chinese medicinal composite for treating burn, scald and ulcer includes oily matrix, coptis chinensis, scutellaria, Phellodendron, frankincense and myrrh. It has obvious curative effect.
Description
The present invention relates to be used for the treatment of the Chinese patent medicine compositions of burn, scald, superficial ulcer, particularly a kind of ointment for curing burns and scalds and promoting tissue generation.
Patent application of the present invention a few days ago, drying open, that use exposes in method and the wet exposing therapy, dry exposed therapy is that to make burn wound penetrate external yellow liquor, congestion, slough dry and hard on wound surface, easy like this blood capillary is stopped up, make the blood capillary malfunction, congestion is penetrated into subcutaneous tissue, cause skin and muscle color to become aubergine, the wound surface pyretic toxicity returns internal organs, can cause multiple complications, wound surface is exposed in the air, makes antibacterial invade wound surface easily and causes silly suppurative infection down; Defectives such as simple moistening exposure method has antibacterial equally invades easily, and the wound surface easy infection suppurates, and poor permeability, pain relieving are slow, wound surface is healed phase is long.
Chinese patent application 86108951 disclosed " processing technology of low melting point ointment dosage form and moist expose burn ointment ", its Main Ingredients and Appearance comprises: Radix Scutellariae, Rhizoma Coptidis, Cortex Phellodendri and Plantula Papaveris, Pheretima, though this burn cream has effects for removing toxic heat, pus expelling by strengthening vital QI putrefaction-removing granulation-promoting function is relatively poor.
Goal of the invention of the present invention is to overcome above-mentioned defective, and a kind of relieving pain, blood circulation promoting and blood stasis dispelling are provided, pus expelling by strengthening vital QI putrefaction-removing granulation-promoting power is strong, wound repair is fast, resistance infection is strong, treatment cycle is short, easy to use, nontoxic and non-irritating ointment for curing burns and scalds and promoting tissue generation.
Foregoing invention purpose of the present invention realizes by following technical proposals:
A kind of ointment for curing burns and scalds and promoting tissue generation comprises: oily wax pattern substrate, choosing add in Rhizoma Coptidis, Radix Scutellariae, the Cortex Phellodendri at least a, it is characterized in that this ointment for curing burns and scalds and promoting tissue generation adds Olibanum, Myrrha, and each component accounts for total dose (% weight): Rhizoma Coptidis: 1-10%; Radix Scutellariae: 1-10%; Cortex Phellodendri: 1-10%; Olibanum: 1-7%; Myrrha: 1-7%.
Ointment for curing burns and scalds and promoting tissue generation has been selected the removing blood stasis pain relieving for use, dissipating blood stasis for subsidence of swelling, the Myrrha of analgesic therapy granulation promoting and have the pain relieving analgesic therapy of putting on flesh, invigorate blood circulation and stretch the Olibanum of muscle, the compound blood circulation promoting and blood stasis dispelling that plays, the function of pus expelling by strengthening vital QI putrefaction-removing granulation-promoting; And, play the anti-infective effect by the invasion and attack of the effects for removing toxic heat of Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri in cream opposing microorganism to wound surface.Olibanum, Myrrha account for total medicine weight ratio: 1-7%, 1-7%, be preferably: 3-5%, 3-5%, described Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri, they can singly be used, also may be mixed together use, each component accounts for total medicine weight ratio: 1-10%, 1-10 %, 1-10% are preferably: 3-8%, 3-8%, 3-8%.
Use for convenience and create a good regenerative environ-ment to wound surface, ointment for curing burns and scalds and promoting tissue generation adopts oily wax pattern substrate, be applied to empyrosis wound surface, both protected wound surface, isolated air again, stop the excessive evaporation of wound surface moisture content, make the slough can dehydrate, with slough from table and in separate with the half-dead non-invasive of organizing with living tissue, make half-dead tissue stop further necrosis, wound surface makes moist at ointment and grows down simultaneously, makes not contracture of wound surface, and small size three degree can flatly heal; Oil wax pattern substrate adopts Oleum Sesami, Cera Flava to mix composition, preferred its compositions fusing point approaches people's body temperature (30 °～40 ℃), purpose is according to wound degree, determine that the coating bed thickness is thin, to ensure that ointment is applied to can be convenient to wound surface and keep medication and drain constantly by temperatureization under the body temperature effect behind the wound surface, make wound surface discharge dead tissue in advance, cleaner wound surface occurs, be convenient to wound repair.
This ointment for curing burns and scalds and promoting tissue generation adopts oily wax pattern substrate ointment promptly to protect wound surface, has isolated air again, has avoided the wound surface drying, and the analgesic effect of Chinese medicine in the cream in addition is so after the medication short-term, wound surface just has tangible analgesic effect.
The Chinese medicine material of choosing is bound up with gauze, put into Oleum sesami and soak, with fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter Oleum Sesami, Cera Flava is a cost cream.This cream is the transparent ointment shape of pale brown color, free from admixture, fusing point: 30 °～40 °.
Toxicity detects:
Select the depilation grouping of healthy rat back, select various dose that ointment is smeared on skin, add a cover plastic sheeting and prevent volatilization, coating washed medication skin repeatedly with clear water after 4 hours, observed for two weeks, saw any poisoning symptom from the beginning and end behind the animals administer, did not have dead the generation.
Zest detects:
Select the depilation grouping of healthy rabbits back, checking smearing respectively on rabbit depilation skin various dose ointment and 10% concentration under the situation of skin zero damage after 24 hours, four layers on reuse gauze is topped fixing, coating is removed topped thing after 4 hours, wash medication skin repeatedly with clear water, observed for two weeks, the result shows: various dose smears red and swollen, the no erythema of skin smooth, nothing in district, do not see any ANOMALOUS VARIATIONS, compare no significant difference with the own control position.
Drug-resistant test:
The external drug sensitive test of lamb: aureus Mlicrococcus Pyogenes var is had inhibitory action.
Using method:
1, general clean middle small area wound can directly be broken and is coated with the cream wrapping after blister discharges water; Pollute the wound surface of ulceration, suitably debridement is removed and is polluted and remove and move the beancurd sheet of taking off, and last cream is wrapped up, and remaining beancurd sheet is looked the wound surface situation and removed later on by stages, and the wound surface beancurd sheet generally was advisable with interior removing after wound in 3-6 days.
2, three degree blister wound surface are hindered the back and were removed beancurd sheet in 2-3 days, are coated with that white liquefaction thing person wound surface not occur behind the cream more shallow, but this cream of scumbling was promptly healed in 2-3 days.Be coated with behind the cream adularescent liquefaction thing and hold out beyond the medicine layer deeplyer, should thickly be coated with diligent coating layer this moment, accelerate wound surface pus expelling by strengthening vital QI putrefaction removing to ensure topical agent for wound surface.After wound surface was controlled by medicine, white liquefaction thing can reduce, but this cream of scumbling is until healing.3-degree wound can thickly be coated with this cream and impel the eschar separation of liquefying in advance, in order to wound repair and skin-grafting, uses this cream and should note clearing up wound surface, carries out once in general 2-3 days.
Ointment for curing burns and scalds and promoting tissue generation of the present invention is applied to that burn, scald and ulcer surface treatment have relieving pain, blood circulation promoting and blood stasis dispelling, pus expelling by strengthening vital QI putrefaction-removing granulation-promoting power is strong, wound repair is fast, dark two degree wound surface preventing from scar, small size three degree can flatly heal, wound surface is contracture not, resistance infection is strong, treatment cycle is short, advantages such as easy to use, nontoxic and nonirritant.
Engaging embodiment below is further described the present invention:
Embodiment 1:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 1 part of Rhizoma Coptidis, 1 part of Radix Scutellariae, 10 parts of Cortex Phellodendris, 1 part of Olibanum, Myrrha bind up with gauze for 1 part, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 2:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 10 parts of Rhizoma Coptidis, 5 parts of Radix Scutellariaes, 1 part of Cortex Phellodendri, 3 parts of Olibanums, Myrrha bind up with gauze for 3 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 3:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 3 parts of Rhizoma Coptidis, 8 parts of Radix Scutellariaes, 8 parts of Cortex Phellodendris, 4 parts of Olibanums, Myrrha bind up with gauze for 4 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 4:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 5 parts of Rhizoma Coptidis, 10 parts of Radix Scutellariaes, 3 parts of Cortex Phellodendris, 5 parts of Olibanums, Myrrha bind up with gauze for 5 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 5:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 8 parts of Rhizoma Coptidis, 3 parts of Radix Scutellariaes, 5 parts of Cortex Phellodendris, 7 parts of Olibanums, Myrrha bind up with gauze for 7 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 6:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 10 parts of Rhizoma Coptidis, 10 parts of Cortex Phellodendris, 7 parts of Olibanums, Myrrha bind up with gauze for 7 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 7:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 10 parts of Radix Scutellariaes, 7 parts of Olibanums, Myrrha bind up with gauze for 7 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 8:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 10 parts of Rhizoma Coptidis, 7 parts of Olibanums, Myrrha bind up with gauze for 7 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Embodiment 9:
A kind of ointment for curing burns and scalds and promoting tissue generation, accounting for total dose (% weight) by the Chinese medicine component takes by weighing: 10 parts of Cortex Phellodendris, 7 parts of Olibanums, Myrrha bind up with gauze for 7 parts, putting into Oleum sesami soaks, with the fire heating that Chinese medicine is fried withered then, pull medicinal residues out, reenter the oily cured substrate of Oleum Sesami, Cera Flava composition, mix homogeneously is made this cream.
Efficacy analysis:
This cream is from clinical trial, treats people surplus the burn and scald 2000 altogether, minimum treatment area 2CM
2, the maximum therapy area accounts for 20% of the whole body gross area.In the statistics 576 treatment examples, male 354 examples, women 222 examples, fresh wound surface 239 examples, outmoded and infective wound surface 337 examples, two degree wound surface, 548 examples, two degree, three degree mix wound surface 18 examples, 3-degree wound 10 examples.Except that 11 routine therapy discontinued persons, all the other are all cured.Shallow two degree wound surface were cured in average 10-12 days, and dark two degree wound surface were cured in average 16-18 days.Two degree, three degree mix wound surface cured in average 24 days, and the 3-degree wound healing of small size is more flat, and clinical short-term is observed dark two degree wound surface and cicatrix do not occurred.
Clinical case:
Cui Wei man facial 2% second degree burn in 26 years old, medication was cured in 6 days, did not stay cicatrix.
Zhang Xiuqing woman upper limb 6% second degree burn in 43 years old, cicatrix is not stayed in medication healing in 10 days.
Auspicious male 42 years old lower limb 10% 2 degree of Wang Zhao scalded, and medication was cured in 10 days, did not stay cicatrix.
28 years old upper body 20% 2 degree of Wang Fu hall man scalded, and medication was cured in 15 days, did not stay cicatrix.
19 years old inboard 20 centimeters * 10 centimeter three degree of left thigh of Li Qiang man scalded, and treats the flat healing of wound surface (not contracture) in 30 days.
Claims (4)
1. an ointment for curing burns and scalds and promoting tissue generation comprises, oily wax pattern substrate, choosing add in Rhizoma Coptidis, Radix Scutellariae, the Cortex Phellodendri at least a, it is characterized in that this ointment for curing burns and scalds and promoting tissue generation adds Olibanum, Myrrha, and each component accounts for total dose (% weight):
Rhizoma Coptidis: 1-10%;
Radix Scutellariae: 1-10%;
Cortex Phellodendri: 1-10%;
Olibanum: 1-7%;
Myrrha: 1-7%.
2. according to the described a kind of ointment for curing burns and scalds and promoting tissue generation of claim 1, it is characterized in that described each component accounts for total dose (% weight):
Rhizoma Coptidis: 3-8%;
Radix Scutellariae: 3-8%;
Cortex Phellodendri: 3-8%;
Olibanum: 3-5%;
Myrrha: 3-5%.
3. according to claim 1 or 2 described a kind of ointment for curing burns and scalds and promoting tissue generation, it is characterized in that described oily wax pattern substrate mixed and formed by Oleum Sesami, Cera Flava.
4. according to the described a kind of ointment for curing burns and scalds and promoting tissue generation of claim 3, the fusing point that it is characterized in that described oily wax pattern substrate is 30 °～40 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95108098A CN1083268C (en) | 1995-07-19 | 1995-07-19 | Ointment for treating burn and scald and promoting tissue regeneration |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN95108098A CN1083268C (en) | 1995-07-19 | 1995-07-19 | Ointment for treating burn and scald and promoting tissue regeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1140596A true CN1140596A (en) | 1997-01-22 |
| CN1083268C CN1083268C (en) | 2002-04-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN95108098A Expired - Fee Related CN1083268C (en) | 1995-07-19 | 1995-07-19 | Ointment for treating burn and scald and promoting tissue regeneration |
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| Country | Link |
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| CN (1) | CN1083268C (en) |
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1094366C (en) * | 1999-12-09 | 2002-11-20 | 谭竹云 | Ointment for treating burn and scald and its preparing process |
| KR100938033B1 (en) * | 2007-10-22 | 2010-01-21 | 남창옥 | Composition for regenerating cells containing Mastic |
| CN102670808A (en) * | 2012-05-24 | 2012-09-19 | 李承平 | Ointment for removing blood stasis and clearing heat |
| CN104491107A (en) * | 2014-12-23 | 2015-04-08 | 杨立猛 | Traditional Chinese medicine preparation for treating burns and preparation method thereof |
| CN104547189A (en) * | 2015-01-07 | 2015-04-29 | 赣南医学院 | Tradtional Chinese medicine composition for treating burns and scalds and preparation thereof |
| CN104825699A (en) * | 2015-04-25 | 2015-08-12 | 孙村镇中药材种植技术协会 | Chinese medicinal plaster for treating skin burn |
| CN104857442A (en) * | 2015-05-22 | 2015-08-26 | 湖南中医药大学 | Traditional Chinese medicine ointment for treating skin ulcer |
| CN108310179A (en) * | 2018-04-18 | 2018-07-24 | 董新声 | A kind of externally applied drug for treating burn and scald |
| CN108785415A (en) * | 2018-08-23 | 2018-11-13 | 普定县科技服务中心 | A kind of drug and preparation method thereof for treating sow mammitis |
| CN109865018A (en) * | 2019-04-12 | 2019-06-11 | 中国医科大学附属第一医院 | Erhuang external preparation and its preparation process |
| CN111514214A (en) * | 2020-04-29 | 2020-08-11 | 南京新康力医药科技有限公司 | Traditional Chinese medicine composition and application |
| CN111840435A (en) * | 2019-04-01 | 2020-10-30 | 武汉济源高科技有限公司 | PRP wound surface granulation promoting ointment |
| CN111905021A (en) * | 2020-09-01 | 2020-11-10 | 颜世伟 | Plaster special for trauma |
| CN111991466A (en) * | 2020-09-22 | 2020-11-27 | 李茂德 | Ointment for treating scald and burn and preparation method thereof |
| CN112274571A (en) * | 2020-12-02 | 2021-01-29 | 西安医学院 | Antibacterial hydrogel suitable for diabetic foot ulcer and preparation method thereof |
| CN112675227A (en) * | 2021-02-01 | 2021-04-20 | 陈守祥 | External medicinal liquor for promoting wound healing and preparation method thereof |
| CN115192649A (en) * | 2022-08-23 | 2022-10-18 | 青海大学 | Application of San Huang Erxiang powder in preparation of medicines for preventing and treating ultraviolet injury, san Huang Erxiang powder extract and cream for preventing and treating ultraviolet injury |
| CN116440194A (en) * | 2023-03-23 | 2023-07-18 | 大连理工大学 | Compound medicine for relieving ulcerative colitis by clysis and application thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1027960C (en) * | 1987-09-01 | 1995-03-22 | 楼宝城 | Prepn. of artificial skin |
| CN1073100A (en) * | 1992-09-30 | 1993-06-16 | 张化文 | Multifunction specific ointment |
| CN1097127A (en) * | 1993-07-03 | 1995-01-11 | 杨宇栋 | Margarita ointment for treating burn and scald and manufacture method |
-
1995
- 1995-07-19 CN CN95108098A patent/CN1083268C/en not_active Expired - Fee Related
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1094366C (en) * | 1999-12-09 | 2002-11-20 | 谭竹云 | Ointment for treating burn and scald and its preparing process |
| KR100938033B1 (en) * | 2007-10-22 | 2010-01-21 | 남창옥 | Composition for regenerating cells containing Mastic |
| CN102670808A (en) * | 2012-05-24 | 2012-09-19 | 李承平 | Ointment for removing blood stasis and clearing heat |
| CN104491107A (en) * | 2014-12-23 | 2015-04-08 | 杨立猛 | Traditional Chinese medicine preparation for treating burns and preparation method thereof |
| CN104547189B (en) * | 2015-01-07 | 2020-04-24 | 赣南医学院 | Traditional Chinese medicine composition for treating burns and scalds and preparation thereof |
| CN104547189A (en) * | 2015-01-07 | 2015-04-29 | 赣南医学院 | Tradtional Chinese medicine composition for treating burns and scalds and preparation thereof |
| CN104825699A (en) * | 2015-04-25 | 2015-08-12 | 孙村镇中药材种植技术协会 | Chinese medicinal plaster for treating skin burn |
| CN104857442A (en) * | 2015-05-22 | 2015-08-26 | 湖南中医药大学 | Traditional Chinese medicine ointment for treating skin ulcer |
| CN108310179A (en) * | 2018-04-18 | 2018-07-24 | 董新声 | A kind of externally applied drug for treating burn and scald |
| CN108785415A (en) * | 2018-08-23 | 2018-11-13 | 普定县科技服务中心 | A kind of drug and preparation method thereof for treating sow mammitis |
| CN111840435A (en) * | 2019-04-01 | 2020-10-30 | 武汉济源高科技有限公司 | PRP wound surface granulation promoting ointment |
| CN109865018A (en) * | 2019-04-12 | 2019-06-11 | 中国医科大学附属第一医院 | Erhuang external preparation and its preparation process |
| CN111514214B (en) * | 2020-04-29 | 2022-03-29 | 南京新康力医药科技有限公司 | Traditional Chinese medicine composition and application |
| CN111514214A (en) * | 2020-04-29 | 2020-08-11 | 南京新康力医药科技有限公司 | Traditional Chinese medicine composition and application |
| CN111905021A (en) * | 2020-09-01 | 2020-11-10 | 颜世伟 | Plaster special for trauma |
| CN111991466A (en) * | 2020-09-22 | 2020-11-27 | 李茂德 | Ointment for treating scald and burn and preparation method thereof |
| CN112274571A (en) * | 2020-12-02 | 2021-01-29 | 西安医学院 | Antibacterial hydrogel suitable for diabetic foot ulcer and preparation method thereof |
| CN112675227A (en) * | 2021-02-01 | 2021-04-20 | 陈守祥 | External medicinal liquor for promoting wound healing and preparation method thereof |
| CN115192649A (en) * | 2022-08-23 | 2022-10-18 | 青海大学 | Application of San Huang Erxiang powder in preparation of medicines for preventing and treating ultraviolet injury, san Huang Erxiang powder extract and cream for preventing and treating ultraviolet injury |
| CN116440194A (en) * | 2023-03-23 | 2023-07-18 | 大连理工大学 | Compound medicine for relieving ulcerative colitis by clysis and application thereof |
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