CN103191228B

CN103191228B - Chinese material medical preparation for scalds and burns

Info

Publication number: CN103191228B
Application number: CN201310117884.4A
Authority: CN
Inventors: 高蓉; 张岚; 田军政
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-04-08
Filing date: 2013-04-08
Publication date: 2014-06-11
Anticipated expiration: 2033-04-08
Also published as: CN103191228A

Abstract

The invention relates to a Chinese material medical preparation for scalds and burns, which is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 5-30 parts of sanguisorba officinalis, 2-15 parts of raw rhubarb, 0.15-0.3 part of borneol, 6-15 parts of angelica sinensis, 10-30 parts of pagoda tree bark, and 1.5-3 parts of jujube bark. Compared with the prior art, the Chinese material medical preparation has no pain in treating scalds and burns, is obvious in curative effect, can achieve 100% effective rate, and can promote wound healing and reduce scar formation: the wound infection can be effectively controlled, the local microcirculation can be improved, the wound can be kept under a physiological wet state, the anhydrobiosis tissue of the wound can be restored and regenerated, and the Chinese material medical preparation for scalds and burns has the functions of inhibiting the collagenous fiber cell proliferation, and promoting the in-situ epithelium regeneration and restoration.

Description

Scald burn Chinese medicine for outer use

Technical field

Human drugs manufacturing technology of the present invention field, is specifically related to a kind of traditional Chinese herb medicine for the treatment of burn and scald preventing from scar.

Background technology

Burn and scald refers to due to hot water, steam, flame, roll wet goods factor acts on a kind of acute injury that body causes, its infringement is many at skin, and severe one can injure subcutaneous muscle; the lighter hinders at epidermis, and local red and swollen heat pain reaches corium deeply compared with severe one; there is blister in part, broken rear wound surface immersion, the red and swollen severe pain in the wound end; severe patient cutaneous necrosis; form eschar, wound surface is without blister, anesthesia; the above patient of moderate often there will be complication, forms disastrous effect.At present, in the burn and scald external application medical ointment of clinical use, the temporary transient effect that does not also have a kind of medicine can play rear preventing from scar in the process for the treatment of burn and scald, and no matter burn and scald degree weight of a lot of burned patients, burn and scald all can have cicatrix at skin surface after curing, because causing large area skin disorganization, burn produces " envelope meat ", make patient's skin can not get back to original state, affect attractive in appearance, bring great pain to patient, and the burn that solves this class problem scalds never appearance of ointment, be therefore necessary to improve.

Summary of the invention

The technical problem that the present invention solves: a kind of burn Chinese medicine for outer use that scalds is provided, and said preparation is preventing from scar after treat in the process of burn and scald, can making patient more, and skin still can return to original state after burn-healing.

Scald burn Chinese medicine for outer use, it is characterized in that being made by following weight parts raw material of Chinese medicine: Radix Sanguisorbae 5---30; Radix Et Rhizoma Rhei 2---15; Borneolum Syntheticum 0.15---0.3; Radix Angelicae Sinensis 6---15, Cortex sophorae 10-30, Cortex Jujubae 1.5---3.

The present invention grinds fine powder by whole raw material of Chinese medicine to add Oleum sesami to make in right amount external-use oil preparation.

The each component effect of the present invention is as follows:

Radix Sanguisorbae---cooling blood for hemostasis, reducing swelling and alleviating pain;

Radix Et Rhizoma Rhei---bowel relieving relieving constipation, XX toxin expelling, stimulate the menstrual flow by silt;

Borneolum Syntheticum---the refreshment of having one's ideas straightened out, heat radiation pain relieving, the detumescence of anti-tumor, improving acuity of vision and removing nebula;

Radix Angelicae Sinensis---tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation;

Cortex sophorae---toxin expelling detumescence, removing dampness to relieve itching;

Cortex Jujubae---hemostasis, improving eyesight, control dysentery antidiarrheal, relieving cough and expelling phlegm.

The present invention is compared with prior art to treatment burn and scald no pain, curative effect is distinguished, effective percentage reaches 100%, it has wound healing, reduces cicatrization: can effectively control traumatic infection, improve local microcirculation, make wound surface keep physiological moisture state, and make the parabiosis tissue of wound surface restore regeneration, and there is the hyperplasia of the collagen fiber of inhibition, promote the function that epithelium in-situ regeneration restores.

The present invention has that physical antibacterial, sticky wound, imbibition are ventilative, the performance of healing acceleration.Also there is stronger anti-infectious function. ami-inflammatory mechanism comprise following some: 1), by changing the biological characteristics of infective wound surface common pathogen, make it to morph, the speed of the bacterial growth that slows down, thereby reduce the pathogenic of antibacterial; 2) the fiber isolating membrane forming at wound surface, can protect wound surface effectively, and the stimulation of isolation surrounding to wound surface, reduces the chance that antibacterial infects; 3) can liquefy with no damage and get rid of wound surface slough, make wound surface drain unobstructed, reduce accumulating of wound surface slough, metabolite, bacteriotoxin etc., clean wound surface, infection control; 4) contained regeneration nutrient substance can provide required various nutrient substance for wound surface regeneration, wherein contained blood circulation promoting and blood stasis dispelling composition can improve wound surface microcirculation effectively, strengthen the immunologic function of wound surface, improve Abwehrkraft des Koepers, thus the generation of protecting from infection.Can be that wound surface is created a physiological moist environment, activate the potency regeneration cell of wound surface deep layer, make it be converted into stem cell, and proliferation and differentiation be skin histology organ, Regeneration and Repair wound surface; Also can be suppressed to fibrocellular hypertrophy simultaneously, reduce the synthetic of collagen protein, thus the formation that alleviates scar tissue.The contained berberine of the present invention has the effect of relaxing smooth muscle, can improve the spasm of microcirculation and releasing arrectores pilorum, thereby reach good analgesic effect.

The specific embodiment

For scalding burn Chinese medicine for outer use, it is made up of following weight parts raw material of Chinese medicine:

Formula 1: Radix Sanguisorbae 5; Raw large 15; Borneolum Syntheticum 0.15; Radix Angelicae Sinensis 15, Cortex sophorae 10, Cortex Jujubae 3.

Formula 2: Radix Sanguisorbae 30, Radix Et Rhizoma Rhei 2; Borneolum Syntheticum 0.3; Radix Angelicae Sinensis 6, Cortex sophorae 30, Cortex Jujubae 1.5.

Formula 3: Radix Sanguisorbae 20, Radix Et Rhizoma Rhei 9, Borneolum Syntheticum 0.2; Radix Angelicae Sinensis 8, Cortex sophorae 18, Cortex Jujubae 2.

Formula 4: Radix Sanguisorbae 15, Radix Et Rhizoma Rhei 12, Borneolum Syntheticum 0.18, Radix Angelicae Sinensis 9, Cortex sophorae 20, Cortex Jujubae 1.8.

Formula 5: Radix Sanguisorbae 25, Radix Et Rhizoma Rhei 8; Borneolum Syntheticum 0.25; Radix Angelicae Sinensis 13, Cortex sophorae 25, Cortex Jujubae 2.5.

After all medicine cleaning-dryings, make external oil by Oleum sesami heating extraction.

Adopt the present invention to make burn oil by oneself and take the various burn and scald of Treated With Mebo; the therapeutical effect such as energy putrefaction-removing granulation-promoting, pain relieving, blood circulation promoting and blood stasis dispelling, infection control, nutrition and protective tissue, promotion regeneration and restoration. healing speed is accelerated; relieving pain; infection rate is low, and clinical effectiveness is good.Treatment can reach without scar healing or shallow soft tissue scar healing, and partial pigment is degenerated, and without organ, nonfunctional obstacle, expense is cheap, is now reported as follows:

1 clinical data

Clinical collection is totally 167 patients, 119 examples of being in hospital, outpatient service 48 examples; Male's 78 examples, women's 41 examples; Age 1-72 year; Above 92 examples of the dark dark type of II degree, following 75 examples of the dark shallow type of II degree; Hot liquid scald 46 examples, flame burn 79 examples, other burn and scald 42 examples; Burn surface area is 30%TBSA-70%TBSA person's 31 examples, 10%-29%TBSA person's 86 examples, following person's 50 examples of 9%TBSA.

1.2 application materials

1.2.1 medicine: self-control Chinese herbal medicine burn and scald preparation (Radix Sanguisorbae 20; Radix Et Rhizoma Rhei 9; Borneolum Syntheticum 0.2; Radix Angelicae Sinensis 8, Cortex sophorae 18, Cortex Jujubae 2, measurement unit is gram that all medicines clean up uses Oleum sesami heating extraction).Normal saline

1.2.2 apparatus and consumptive material: the aseptic curved basin of changing dressings, tweezers, tissue scissors, ploughing and weeding cutter, sterilized cotton ball, self-control burn and scald treating oil and dressing cream.

2 Therapeutic Method

2.1 whole body therapeutic

The quick diagnosis state of an illness, II degree burn and scald injures above, and area is greater than more than 10% will set up rapidly venous access, carry out the treatments such as dilatation, shock, infection, nutritional support. less to area, I degree burn and scald the wounded, without the transfusion of application antibiotic, oral antibiotic just can.

2.2 debridements and burn and scald dressing cream are changed dressings and are carried out wound surface while processing, fully expose wound surface, hide and should open gently or cut off if any medicated clothing, avoid tearing as far as possible, wipe and cause exfoliation; Pollute wound surface and can use normal saline flushing, clear the pollution off in time or pile up the beancurd sheet coming off; Larger vesicle breaks with sterilization shears low level, retains bleb skin after discharging water; Deep wounds needs timely row ploughing and weeding to subtract a processing. after debridement; with sterilization dry gauze exhaustion wound surface moisture; directly will be from pharmacy and scalding surgical dressing cream uniform fold at wound surface; thick about 1-2mm; change dressings 1-2 every day; remaining that wound surface is moistening has a medicine. and while changing dressings, wipe wound surface liquefied substance and residual ointment away with aseptic wet cotton balls, clean wound surface every day 1 time; After cleaning wound surface, must dip in solid carbon dioxide divides, in order to avoid hydrone destroys medicines structure, affect the treatment, constantly smear and keep moistening with burn and scald treating oil at red and swollen place, side, until wound healing. omnidistance medication: uninterrupted medication in therapeutic process, should not use other therapies or medicine midway instead.

While changing dressings, should follow " three should not " principle: wound surface should not pain, should not be hemorrhage, should not damage normal structure.

3 results

The healing in 5-9 days of I degree empyrosis wound surface; The healing in 12-15 days of light degree Ⅱ wound surface; The healing in 11-18 days of the dark shallow type wound surface of II degree; The dark dark type wound surface of II degree healed about 20 days; The shallow type wound surface of III degree healed about 25 days; The dark type wound surface of III degree healed about 35 days, did not stay cicatrix or shallow soft tissue scar healing, but had partial pigment to degenerate; II hybrid degree fire victim is without obvious heating paresthesia, and the dark above fire victim of the dark type of II degree of part has moderate heating, but few high heat; Without 1 routine concurrent antibacterial and fungal infection. and patient suffering is little, expense is cheap. and also have smouldering property stain infections and herpes zoster are had to good curative effect.

4 discuss

The present invention is scalded burn oil and is had lipotropy, is applied to after wound surface, has the therapeutical effect such as putrefaction-removing granulation-promoting, pain relieving, blood circulation promoting and blood stasis dispelling, infection control, nutrition and protective tissue, promotion regeneration and restoration.

Specifically, the present invention treats and scalds burn and have a following effect:

Analgesic effect: be subject to after wound, epidermis is impaired, teleneuron exposes, and microcirculation is retarded by silt, teleneuron anoxia, and other foreign bodies, histamine, the invasion and attack of the oxygen-derived free radicals factor etc. all can cause pain.The present invention can be wound surface moistening environment is provided, thereby neuroprotective tip improves microcirculation, plays analgesic effect.

Anti-infectious function: after skin damage, lost natural cover for defense effect.Can make wound surface be isolated from the outside, reduce antibacterial and infect, and discharge in time the secretions in wound surface by " automatic jet " mode.In addition, the cupreol in MEBO and baicalin are the antibiotic of low toxicity wide spectrum, growth and breeding that can anti-bacteria, and make bacterial dissociation, do not produce toxin or do not have an aggressivity, thereby play anti-infectious function.

Claims

1. for scalding burn Chinese medicine for outer use, it is characterized in that being made by following weight parts raw material of Chinese medicine: Radix Sanguisorbae 5---30; Radix Et Rhizoma Rhei 2---15; Borneolum Syntheticum 0.15---0.3; Radix Angelicae Sinensis 6---15, Cortex sophorae 10-30, Cortex Jujubae 1.5---3.

2. according to claim 1 for scalding burn Chinese medicine for outer use, it is characterized in that whole raw material of Chinese medicine grind fine powder and add Oleum sesami to make in right amount external-use oil preparation.