CN103191228A

CN103191228A - Chinese material medical preparation for scalds and burns

Info

Publication number: CN103191228A
Application number: CN2013101178844A
Authority: CN
Inventors: 高蓉; 张岚; 田军政
Original assignee: 高蓉
Priority date: 2013-04-08
Filing date: 2013-04-08
Publication date: 2013-07-10
Anticipated expiration: 2033-04-08
Also published as: CN103191228B

Abstract

The invention relates to a Chinese material medical preparation for scalds and burns, which is characterized by comprising the following traditional Chinese medicine raw materials in parts by weight: 5-30 parts of sanguisorba officinalis, 2-15 parts of raw rhubarb, 0.15-0.3 part of borneol, 6-15 parts of angelica sinensis, 10-30 parts of pagoda tree bark, and 1.5-3 parts of jujube bark. Compared with the prior art, the Chinese material medical preparation has no pain in treating scalds and burns, is obvious in curative effect, can achieve 100% effective rate, and can promote wound healing and reduce scar formation: the wound infection can be effectively controlled, the local microcirculation can be improved, the wound can be kept under a physiological wet state, the anhydrobiosis tissue of the wound can be restored and regenerated, and the Chinese material medical preparation for scalds and burns has the functions of inhibiting the collagenous fiber cell proliferation, and promoting the in-situ epithelium regeneration and restoration.

Description

Scald the burn Chinese medicine for outer use

Technical field

Human drugs manufacturing technology of the present invention field is specifically related to a kind of traditional Chinese herb medicine for the treatment of the burn and scald preventing from scar.

Background technology

Burn and scald refers to owing to hot water, steam, flame, roll the wet goods factor acts on a kind of acute injury that body causes, its infringement is many at skin, and weight person can injure subcutaneous muscle; the lighter hinders at epidermis, local red and swollen heat pain, and heavier person reaches corium deeply; blister appears in the part, the wound surface immersion of broken back, the red and swollen severe pain in the wound end; the severe patient cutaneous necrosis; form eschar, wound surface does not have blister, anesthesia; the above patient of moderate regular meeting develops complications, and forms disastrous effect.At present, in the burn and scald external application medical ointment of clinical use, temporary transient also do not have a kind of medicine can play the more effect of back preventing from scar in the process for the treatment of burn and scald, and a lot of burn and scald patients burn and scald degree weight no matter, burn and scald all can have cicatrix at skin surface after curing, because burn causes that the large area skin disorganization has produced " envelope meat ", make patient's skin can not get back to original state, influenced attractive in appearance, bring huge misery to the patient, and the burn that solves this class problem scalds never appearance of ointment, therefore is necessary to improve.

Summary of the invention

The technical problem that the present invention solves: a kind of boiling hot burn Chinese medicine for outer use is provided, and said preparation can make more back preventing from scar of patient, and skin still can return to original state behind burn-healing in the process for the treatment of burn and scald.

Scald the burn Chinese medicine for outer use, it is characterized in that being made by the following weight parts raw material of Chinese medicine: Radix Sanguisorbae 5---30; Radix Et Rhizoma Rhei 2---15; Borneolum Syntheticum 0.15---0.3; Radix Angelicae Sinensis 6---15, Cortex sophorae 10-30, Cortex Jujubae 1.5---3.

The present invention grinds fine powder adding Oleum sesami with whole raw material of Chinese medicine to make external-use oil preparation in right amount.

Each component effect of the present invention is as follows:

Radix Sanguisorbae---cooling blood for hemostasis, reducing swelling and alleviating pain;

Radix Et Rhizoma Rhei---bowel relieving relieving constipation, XX toxin expelling, stimulate the menstrual flow by becoming silted up;

The Borneolum Syntheticum---refreshment of having one's ideas straightened out, heat radiation pain relieving, anti-tumor detumescence, improving acuity of vision and removing nebula;

Radix Angelicae Sinensis---tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation;

Cortex sophorae--the detumescence of-toxin expelling, removing dampness to relieve itching;

Cortex Jujubae---stop blooding, make eye bright, control dysentery antidiarrheal, relieving cough and expelling phlegm.

The present invention is compared with prior art to treatment burn and scald no pain, curative effect is distinguished, effective percentage reaches 100%, it has the promotion wound healing, reduces cicatrization: can effectively control traumatic infection, improve local microcirculation, make wound surface keep the physiological moisture state, and make the parabiosis tissue of wound surface restore regeneration, and have the hyperplasia of the collagen fiber of inhibition, promote the function that the epithelium in-situ regeneration restores.

The present invention has that physical antibacterial, sticking wound, imbibition are ventilative, the performance of healing acceleration.Also have stronger anti-infectious function. anti-infectious function mechanism comprise following some: 1) by changing the biological characteristics of infective wound surface common pathogen, make it to morph, the speed of the bacterial growth that slows down, thereby reduce the pathogenic of antibacterial; 2) the fiber isolating membrane that forms at wound surface can be protected wound surface effectively, isolates surrounding to the stimulation of wound surface, reduces the chance of bacterial infection; 3) can liquefy with no damage and get rid of the wound surface slough, make the wound surface drain unobstructed, reduce accumulating of wound surface slough, metabolite, bacteriotoxin etc., the cleaning wound surface, control is infected; 4) contained regeneration nutrient substance can provide required various nutrient substance for wound surface regeneration, and wherein contained blood circulation promoting and blood stasis dispelling composition can improve the wound surface microcirculation effectively, strengthens the immunologic function of wound surface, improves Abwehrkraft des Koepers, thus the generation of protecting from infection.Can create a physiological moist environment for wound surface, activate the potency regeneration cell of wound surface deep layer, make it be converted into stem cell, and proliferation and differentiation is the skin histology organ, the Regeneration and Repair wound surface; Also can be suppressed to fibrocellular hypertrophy simultaneously, reduce the synthetic of collagen protein, thus the formation that alleviates scar tissue.The contained berberine of the present invention has the effect of relaxing smooth muscle, can improve the spasm of microcirculation and releasing arrectores pilorum, thereby reach good analgesic effect.

The specific embodiment

Be used for scalding the burn Chinese medicine for outer use, it is made by the following weight parts raw material of Chinese medicine:

Prescription 1: Radix Sanguisorbae 5; Give birth to big by 15; Borneolum Syntheticum 0.15; Radix Angelicae Sinensis 15, Cortex sophorae 10, Cortex Jujubae 3.

Prescription 2: Radix Sanguisorbae 30, Radix Et Rhizoma Rhei 2; Borneolum Syntheticum 0.3; Radix Angelicae Sinensis 6, Cortex sophorae 30, Cortex Jujubae 1.5.

Prescription 3: Radix Sanguisorbae 20, Radix Et Rhizoma Rhei 9, Borneolum Syntheticum 0.2; Radix Angelicae Sinensis 8, Cortex sophorae 18, Cortex Jujubae 2.

Prescription 4: Radix Sanguisorbae 15, Radix Et Rhizoma Rhei 12, Borneolum Syntheticum 0.18, Radix Angelicae Sinensis 9, Cortex sophorae 20, Cortex Jujubae 1.8.

Prescription 5: Radix Sanguisorbae 25, Radix Et Rhizoma Rhei 8; Borneolum Syntheticum 0.25; Radix Angelicae Sinensis 13, Cortex sophorae 25, Cortex Jujubae 2.5.

Making external oil with the Oleum sesami heating extraction behind all medicine cleaning-dryings gets final product.

Adopting the present invention to make burn oil by oneself takes wet exposing therapy to treat various burn and scald; therapeutical effect such as energy putrefaction-removing granulation-promoting, pain relieving, blood circulation promoting and blood stasis dispelling, control infection, nutrition and protective tissue, promotion regeneration and restoration. healing speed is accelerated; relieving pain; infection rate is low, and clinical effectiveness is good.Treatment can reach no scar healing or shallow soft tissue scar healing, and partial pigment is degenerated, no organ, no dysfunction, and expense is cheap, now is reported as follows:

1 clinical data

Clinical collection is totally 167 patients, 119 examples of being in hospital, outpatient service 48 examples; Male's 78 examples, women's 41 examples; Age 1-72 year; Above 92 examples of the dark dark type of II degree, following 75 examples of the dark shallow type of II degree; Hydrothermal solution is scalded 46 examples, flame burn 79 examples, other burn and scald 42 examples; Burn surface area is 30%TBSA-70%TBSA person's 31 examples, 10%-29%TBSA person's 86 examples, following person's 50 examples of 9%TBSA.

1.2 Material Used

1.2.1 medicine: self-control Chinese herbal medicine burn and scald preparation (Radix Sanguisorbae 20; Radix Et Rhizoma Rhei 9; Borneolum Syntheticum 0.2; Radix Angelicae Sinensis 8, Cortex sophorae 18, Cortex Jujubae 2, measurement unit is gram, all medicines clean up uses the Oleum sesami heating extraction).Normal saline

1.2.2 apparatus and consumptive material: the aseptic curved basin of changing dressings, tweezers, tissue scissors, ploughing and weeding cutter, sterilized cotton ball, self-control burn and scald treating oil and dressing cream.

2 Therapeutic Method

2.1 whole body therapeutic

The quick diagnosis state of an illness, II degree burn and scald injures above, and area is greater than setting up venous access rapidly more than 10%, carry out treatments such as dilatation, shock, infection, nutritional support. less to area, I degree burn and scald the wounded need not to use the antibiotic transfusion, and oral antibiotic just can.

Carry out wound surface when handling 2.2 debridement and burn and scald dressing cream are changed dressings, fully expose wound surface, hide and to open gently or to cut off if any medicated clothing, avoid tearing as far as possible, wipe and cause exfoliation; Pollute wound surface and can use normal saline flushing, in time clear the pollution off or pile up the beancurd sheet that comes off; Bigger vesicle is broken with sterilization shears low level, and the back that discharges water keeps the bleb skin; Degree of depth wound surface needs row ploughing and weeding in time to subtract a processing. after the debridement, with sterilization dry gauze exhaustion wound surface moisture, directly will and scald dressing cream from pharmacy and evenly cover wound surface, thick about 1-2mm, change dressings 1-2 every day, remain that wound surface is moistening a medicine. wipe wound surface liquefaction thing and residual ointment away with aseptic wet cotton balls when changing dressings, clean wound surface every day 1 time; Must dip in the solid carbon dioxide branch after cleaning wound surface, in order to avoid hydrone destroys medicines structure, affect the treatment, constantly smear with burn and scald treating oil and keep moistening at red and swollen place, next door, until wound healing. omnidistance medication: uninterrupted medication in the therapeutic process, should not use other therapies or medicine midway instead.

Should follow " three should not " principle when changing dressings: wound surface should not pain, should not be hemorrhage, should not damage normal structure.

3 results

The healing in 5-9 days of I degree empyrosis wound surface; The healing in 12-15 days of light degree wound surface; The healing in 11-18 days of the dark shallow type wound surface of II degree; The dark dark type wound surface of II degree healed about 20 days; The shallow type wound surface of III degree healed about 25 days; The dark type wound surface of III degree healed about 35 days, did not stay cicatrix or shallow soft tissue scar healing, but had partial pigment to degenerate; II hybrid degree fire victim does not have obvious heating paresthesia, and the dark above fire victim of the dark type of II degree of part has the moderate heating, but few high heat; There is not 1 routine concurrent antibacterial and fungal infection. and the patient suffering is little, expense is cheap. in addition smouldering property stain infections and herpes zoster there are better curative effect.

4 discuss

The present invention is scalded burn oil and is had lipotropy, be applied to wound surface after, have therapeutical effect such as putrefaction-removing granulation-promoting, pain relieving, blood circulation promoting and blood stasis dispelling, control infection, nutrition and protective tissue, promotion regeneration and restoration.

Specifically, the present invention treats and scalds burn and have following effect:

Analgesic effect: after being subjected to wound, epidermis is impaired, and teleneuron exposes, and microcirculation is retarded by silt, the teleneuron anoxia, and other foreign bodies, histamine, the invasion and attack of the oxygen-derived free radicals factor etc. all can cause pain.The present invention can be wound surface moistening environment is provided, thereby the neuroprotective tip improves microcirculation, plays analgesic effect.

Anti-infectious function: after the skin damage, lost natural cover for defense effect.Wound surface is isolated from the outside, reduces bacterial infection, and in time discharge the interior secretions of wound surface by " automatic jet " mode.In addition, the cupreol among the MEBO and baicalin are the antibiotic of low toxicity wide spectrum, can suppress the growth and breeding of antibacterial, and make bacterial dissociation, do not produce toxin or do not have an aggressivity, thereby play anti-infectious function.

Claims

1. be used for scalding the burn Chinese medicine for outer use, it is characterized in that being made by the following weight parts raw material of Chinese medicine: Radix Sanguisorbae 5---30; Radix Et Rhizoma Rhei 2---15; Borneolum Syntheticum 0.15---0.3; Radix Angelicae Sinensis 6---15, Cortex sophorae 10-30, Cortex Jujubae 1.5---3.

2. described for scalding the burn Chinese medicine for outer use according to claim 1, it is characterized in that whole raw material of Chinese medicine grind fine powder adding Oleum sesami and make external-use oil preparation in right amount.