CN1188144C - Medicine for curing human body burns and scalds - Google Patents

Abstract

The present invention relates to medicine for curing human body burns and scalds. The medicine is characterized in that the medicine is an aqueous extract liquid including 10 portions of dandelion, 0.5 to 5 portions of argyi leaves and 5 to 10 portions of tonglingcao by weight. The medicine is reasonable in medicine administrating methods, and accordingly, the pain of patients is reduced. Simultaneously, the medicine has obvious functions for resisting infection, removing necrosis and promoting myogenesis.

Description

A kind of medicine and preparation method for the treatment of human body burns and scalds

The present invention relates to treat the medicine of human body burns and scalds, a kind of Chinese herbal and crude drugs preparations of scalding usefulness for the treatment of is provided especially.

Skin is one of main Excretory organ of human body, under the normal physiological situation, sweat gland is discharged moisture and electrolyte, epidermal area plays isolates the destruction of the Nature to skin histology, the microcirculation network plays tissue and supports and oxygen metabolism thing transmission effect, the effect that improves histiocytic moist environment and growing environment is played in tissue fluid, and the appendages of skin also rise and regulate the whole body systemic effect when regulating the skin histology function.In case behind the skin burn and scald, normal regulative mechanism and barrier action have just been lost, make a large amount of water evaporates, but residue in subcutaneous body of gland and still preserve secretory function, so the burn back stops water evaporates, and don't hinder perspiration and excretory local therapeutic approaches of moisture and the medicine that its special efficacy is arranged, paid close attention to by numerous experts at present.Burn and scald is the ischemia injury after the human body skin barrier is damaged, and simple pathogenic process is: burn → necrosis → slough comes off → remaining tissue regeneration → reparation.Its treatment aim is " removing the necrotic tissue life ", " regaining the function ", so must be to be principle with " Regeneration and Repair " to the research of burn and scald topical therapeutic.At present mostly the applied burn and scald medicine of each hospital is the ointment smeared to be used for wound surface after a few hours, need remove the repetitive process of repaste, causes huge misery to the patient.Though burn and scald hinder face area size, as long as epidermal tissue is damaged, the water outlet phenomenon just appearred after a few hours, dark II degree to III degree is hindered surface current and is gone out to occur behind the blood and slime white colloidal thing wound surface after 24 hours and light yellow dope occurs and constantly discharge, and the very thick crust of formation, with present conventional coating method, thick crust indissoluble, thereby can not entering, medicine hinders in the covering weave and the delay treating time repeated infection, or also infection suppurates of good skin, especially the dark above face length time of hindering of II degree does not heal, nearly half a year.

The object of the present invention is to provide a kind of medicine for the treatment of human body burns and scalds, its application method is reasonable, thereby has alleviated patient's misery, has the effect of tangible infection, putrefaction-removing granulation-promoting simultaneously.

The invention provides a kind of medicine for the treatment of human body burns and scalds, it is characterized in that this medicine is the water extract of 10 parts of weight Herba Taraxacis, 0.5～5 part of weight Folium Artemisiae Argyi, 5～10 parts of weight Flos Loniceraes.

The effect of each Chinese herbal medicine of the present invention is that Herba Taraxaci can be coordinated epithelial tissue and connective tissue regeneration; Folium Artemisiae Argyi can antibiotic, antiinflammatory; Flos Lonicerae can wound repairing, preventing from scar.

Chinese herbal medicine concentrating agents of the present invention, with spray behind the moistening wound surface of method, can very fast molten crust, infiltrate in the wound surface deep tissues, form a kind of protecting film, stop extraneous the infection, promotes new granulation growth, anti-reticular layer of corium infects and recovery.

Preparation method of the present invention is as follows:

(1) Herba Taraxaci is adopted Herb, cleans to dry in the shade;

(2) Folium Artemisiae Argyi, the Herb of taking aerial parts, 2 centimetres of sections of cutting system are dried in the shade (yellow leaf goes rotten), 5～June of acquisition time;

(3) Flos Lonicerae is long bar-shaped, is about 2～3 centimetres, and yellow skin is white;

Above-mentioned raw materials is through cleaning, and---------filter---bottling---sterilization and obtain Chinese medicine preparation, applying portion is an aqueous solution in the decocting in water extraction in immersion.

The present invention is according to the tame poultry test of over thousands of example, and by skin of pig and people's the close characteristics of skin, repetition test medical treatment prescription forms.The inspection information masterpiece all has following saying; After skin, corium part and most of the burn, the healing of its wound surface has three kinds of modes after all, one, and the remaining hypodermal cell of wound surface reaches wound healing along the growth of directly stretching under the crust, leaves hypertrophic cicatrix; Its two, burn back skin layer comes off, wound surface is skin island granulation state, must transplant consubstantiality skin flap coverage and heals or repeatedly change dressings and heal, and leaves the skin-grafting cicatrix; Its three, the early stage realization cut the crust skin grafting, makes wound surface skin-grafting healing, leaves cicatrix, medicine of the present invention is not made skin graft to dark II degree, III degree burn and is cured no cicatrix.

Be in particular in:

(1) molten crust is rapid, and after 20 minutes, incrustation is dissolved in medication, and the crust about 1 centimetre can come off voluntarily.

(2) anti-infection ability is strong, behind the removing wound surface, sprays medicinal liquid and formed layer protecting film after 1 hour, stops outside the infection.

(3) minimizing is oozed out, and to dark II degree, III degree burn and scald, oozes out minimizing through 2～3 days spray medicine blood plasma, does not ooze out substantially after 5～7 days.

(4) epidermal tissue's growing way is rapid, and after 3～5 days, wound surface will have new epidermal growth every day in medication, and observing on face 12 examples hindering of dark II degree will have 0.8～1 centimetre ramp every day.

(5) routine treatment will be carried out the consubstantiality skin-grafting to dark II degree, III degree burn, after bandage protection, once changed dressings in 5～7 days, in case the skin-grafting failure is suppurated fast, use medicine of the present invention, do not have repeated infection and comparatively fast fully recover.

(6) innovative point of this medicine: remaining cell is regenerated rapidly.Clinical practice proves, deep ii degree burn area 18～24%, recovery from illness in 12 days.

From 1998 to 2000, accumulative total was used 168 examples, and wherein I to II degree 58 examples were fully recovered in 5 to 7 days.The II degree is to the recovery from illness in 12～18 days of dark II degree 34 examples.Dark II degree to III degree 76 examples were fully recovered at 38～45 days.

Below by embodiment in detail the present invention is described in detail.

Embodiment 1

Dosage form I: Herba Taraxaci 100g, Folium Artemisiae Argyi 50g, each 50g of Flos Lonicerae adds 2000 liters in water, is condensed into 100～120 milliliters.

Dosage form II: Herba Taraxaci 100g, Folium Artemisiae Argyi 30g, each 70g of Flos Lonicerae adds 2000 liters in water, is condensed into 100～120 milliliters.

Dosage form III: Herba Taraxaci 100g, Folium Artemisiae Argyi 20g, each 100g of Flos Lonicerae adds 2000 liters in water, is condensed into 100～120 milliliters.

The wounded Zhu Zhi east, agricultural vehicle overturns, boiling water in the water tank waters to upper body area 24.6%, through three tame hospitals change control be diagnosed as dark II degree, the III degree does not wait, carry out traditional skin grafting after living in Chaoyang City hospital, work is held up except fraction in (because kidney is injured simultaneously) skin-grafting back, and the overwhelming majority further worsened after 40 days, the right side spills rib, and the result is:

Owing to can not take medical expense, and stop treatment.

With Drug therapy dosage form I treatment of the present invention 5 days, dosage form II treatment 15 days, then as follows with dosage form III therapeutic outcome:

(1) Pyatyi vascular tree regeneration → subcuticle vasoganglion forms;

(2) the remaining dermal tissue of the netted formation skin of fibrous tissue → high dermis;

(3) remaining body of gland → regeneration → epidermis holostrome forms and covers, newborn corium and healing → no cicatrix.

After finding the most of burn of dermis of skin thus, remaining dermal tissue is in inhibitory state, the tissue that viability was arranged on the 3rd day begins to become glossy bright-coloured, after the 7th day, become living tissue to begin to separate with slough, pus shape slough becomes shallow white, dashes and comes off along with the spray of medicinal liquid, and the tissue that survives becomes granulation.Vasoganglion enlarges regeneration according to original tissue morphology.The subcutaneous tissue variation also changes, and grows tunica albuginea earlier in the ribbed place of dew, and gland cell is changed into the epidermal basal cell of no secreting type by secreting type.

Embodiment 2

The worker Xiao of Ka Zuo county Education Commission, the man, 40 years old, cylinder for liquefied gas was on fire, and flame to whole body catches fire, and it is facial burning heavier, becomes livid purple color very soon, serious edema.Entire face was twice than swollen with original.Also fuzzy with expression, fever 38～39 degree.

After living in Department of B urn, every days 1,140 ten thousand, the penicillin dead point dashed with the used medicine spray of embodiment 1 for 5 to 6 times, be specially dosage form I treatment 3 days, dosage form II treatment 10 days, then as follows with dosage form III therapeutic outcome: the light red streak appearred in rear face in seven days, the taupe exfoliation.Continued medication seven days, entire face only have six fritters hinder face darker have a thin crust, no extract does not have and keenly feels, and heals only 950 milliliters of the medications of whole therapeutic process behind two fortnights entirely.

Use microscopy, make after tens minutes at the spray medicine and hinder the surface skin deliquescing, through five to seven days medication; make and hinder face and separate (downright bad epidermis) in bulk with epidermis and come off; and make skin surface layer protecting film occur, and stop outside the infection, after spraying medicine several times, make the thin film deliquescing again; very fast absorption medicinal liquid enters epidermis and stratum basale; make protecting film progressive additive in 48 hours, medication in the time of 4～5 days this film come off, lose exudate; and the flat face of hindering is covered in healing, recovers former state.

Embodiment 3

Li Jinhua, the woman, 9 years old, the student, because of the tricycle of taking overturns, the boiled water in the water tank flows out, and waters the lower limb this girl, and JIUYUE was lived Department of B urn on 5th in 2000, was diagnosed as II to III degree and scalded area 24%.

After being in hospital, inappetence, fever, body temperature is at 38.5～39 degree, dead point Ceftriaxone and six-aminoacid.The outer treatment with burn-scald medicine every day of embodiment 1 4～5 times, night 1～2 time, each 50～60 milliliters, dosage form I treatment is 3 days particularly, and dosage form II treatment 10 days is then as follows with dosage form III therapeutic outcome:.

Medication after three days the II degree hinder the face drying, do not hinder the edge on every side and corrugate, the III degree is hindered face has yellow pus thing to discharge, incrustation fast behind the spray medicine becomes the red shape and flows out.

After the medication seven days, the II degree is hindered face on every side to spread to the centre 1～1.5 centimetre of every day, and the III degree is hindered the face extract and reduced gradually, and grows granulation from hindering the face bottom.

After 15 days, hinder face from inwardly fast growth of periphery, on inspection, gland cell is converted into the epidermis stem floor cells of no secreting type by secreting type, and the position of forming a scab becomes more bright-coloured new meat, through 46 days treatment, more leaves hospital entirely.

Claims (2)

1, a kind of medicine for the treatment of human body burns and scalds is characterized in that this medicine is the water extract of 10 parts of weight Herba Taraxacis, 0.5～5 part of weight Folium Artemisiae Argyi, 5～10 parts of weight Flos Loniceraes.

2, the preparation method of the described treatment human body burns and scalds of a kind of claim 1 medicine is characterized in that:

(1) Herba Taraxaci is adopted Herb, cleans to dry in the shade;

(2) Folium Artemisiae Argyi, the Herb of taking aerial parts, the yellow leaf that goes rotten not, in 5～June of acquisition time, 2 centimetres of sections of cutting system are dried in the shade;

(3) Flos Lonicerae is long bar-shaped, is about 2～3 centimetres, and yellow skin is white;

Above-mentioned raw materials is through cleaning, and------the decocting in water extraction---is filtered---bottling---sterilization and is obtained Chinese medicine preparation in immersion.