CN114010835A - Production process of ultrahigh-filtration medical breathable bag beneficial to healing - Google Patents
Production process of ultrahigh-filtration medical breathable bag beneficial to healing Download PDFInfo
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- CN114010835A CN114010835A CN202111264886.7A CN202111264886A CN114010835A CN 114010835 A CN114010835 A CN 114010835A CN 202111264886 A CN202111264886 A CN 202111264886A CN 114010835 A CN114010835 A CN 114010835A
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- woven fabric
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- sponge
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- 238000001914 filtration Methods 0.000 title claims abstract description 17
- 230000035876 healing Effects 0.000 title claims abstract description 17
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 13
- 230000009286 beneficial effect Effects 0.000 title abstract description 8
- 238000000576 coating method Methods 0.000 claims abstract description 34
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 32
- 230000001954 sterilising effect Effects 0.000 claims abstract description 27
- 239000011248 coating agent Substances 0.000 claims abstract description 25
- 238000010438 heat treatment Methods 0.000 claims abstract description 20
- 238000006243 chemical reaction Methods 0.000 claims abstract description 17
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 13
- 238000001035 drying Methods 0.000 claims abstract description 13
- 229920000159 gelatin Polymers 0.000 claims abstract description 13
- 239000008273 gelatin Substances 0.000 claims abstract description 13
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 claims abstract description 12
- 108010010803 Gelatin Proteins 0.000 claims abstract description 12
- 235000019322 gelatine Nutrition 0.000 claims abstract description 12
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 12
- 238000002156 mixing Methods 0.000 claims abstract description 12
- 238000003756 stirring Methods 0.000 claims abstract description 12
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 10
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 10
- UPMLOUAZCHDJJD-UHFFFAOYSA-N 4,4'-Diphenylmethane Diisocyanate Chemical compound C1=CC(N=C=O)=CC=C1CC1=CC=C(N=C=O)C=C1 UPMLOUAZCHDJJD-UHFFFAOYSA-N 0.000 claims abstract description 8
- WERYXYBDKMZEQL-UHFFFAOYSA-N butane-1,4-diol Chemical compound OCCCCO WERYXYBDKMZEQL-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 7
- 239000004744 fabric Substances 0.000 claims abstract description 6
- 239000012752 auxiliary agent Substances 0.000 claims abstract description 4
- 239000003054 catalyst Substances 0.000 claims abstract description 4
- 239000003431 cross linking reagent Substances 0.000 claims abstract description 4
- 229920005906 polyester polyol Polymers 0.000 claims abstract description 4
- 229910052710 silicon Inorganic materials 0.000 claims abstract description 4
- 239000010703 silicon Substances 0.000 claims abstract description 4
- 239000003292 glue Substances 0.000 claims description 24
- 238000000034 method Methods 0.000 claims description 13
- 230000008569 process Effects 0.000 claims description 12
- 239000002994 raw material Substances 0.000 claims description 8
- 238000005520 cutting process Methods 0.000 claims description 6
- 239000003206 sterilizing agent Substances 0.000 claims description 4
- DEAWGQRVWXXTPD-UHFFFAOYSA-N 6-fluoro-3-(6-fluoroimidazo[1,2-a]pyridin-3-yl)imidazo[1,2-a]pyridine Chemical compound Fc1ccc2ncc(-c3cnc4ccc(F)cn34)n2c1 DEAWGQRVWXXTPD-UHFFFAOYSA-N 0.000 claims description 3
- 239000003899 bactericide agent Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims description 2
- 230000029663 wound healing Effects 0.000 abstract description 4
- 239000012567 medical material Substances 0.000 abstract description 2
- 238000007789 sealing Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 description 15
- 208000015181 infectious disease Diseases 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 239000003242 anti bacterial agent Substances 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 229920000742 Cotton Polymers 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 229920000297 Rayon Polymers 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 238000001266 bandaging Methods 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- ZHNUHDYFZUAESO-UHFFFAOYSA-N formamide Substances NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 230000002439 hemostatic effect Effects 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
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- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/00051—Accessories for dressings
- A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
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- A61F13/02—Adhesive bandages or dressings
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- A61F13/00—Bandages or dressings; Absorbent pads
- A61F13/02—Adhesive bandages or dressings
- A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
- A61F13/0289—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of adhesive dressings
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
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- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
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- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/425—Porous materials, e.g. foams or sponges
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- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
- A61F2013/00361—Plasters
- A61F2013/00855—Plasters pervious to air or vapours
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
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Abstract
The invention relates to the technical field of medical materials, in particular to a production process of an ultrahigh-filtration medical breathable bag beneficial to healing, which comprises the following steps: s1, preparing an outer coating reagent; selecting diphenylmethane diisocyanate, polyester polyol, a cross-linking agent, an antioxidant, organic silicon and methyl ethyl ketone, mixing and stirring, and then carrying out heating reaction to obtain an initial product; adding 1, 4-butanediol into the primary product, mixing and stirring, and then carrying out heating reaction to obtain a secondary product; adding a catalyst, diphenylmethane diisocyanate and an auxiliary agent into the secondary product, and uniformly stirring and mixing to obtain a finished product of the external coating reagent; s2, coating the finished product of the external coating reagent on the bottom surface of the elastic non-woven fabric and drying; s3, preparing a sterilizing sponge frame; s4, the gelatin sponge block and the sterilization sponge frame are adhered to the middle of the top surface of the elastic non-woven fabric; s5, sealing the top surface of the elastic non-woven fabric by using a covering film; the obtained medical wrapping cloth is not only beneficial to wound healing, but also good in waterproofness and breathability.
Description
Technical Field
The invention relates to the technical field of medical materials, in particular to a production process of an ultrahigh-filtration medical breathable bag beneficial to healing.
Background
The dressing is one of important measures for emergency treatment of trauma sites, can achieve the purposes of compression hemostasis, infection reduction, wound protection, pain reduction, dressing and splint fixation and the like by timely and correctly dressing, and on the contrary, the wrong dressing can lead to increased bleeding, aggravated infection, new injury, sequela retention and other adverse consequences. One essential material in the binding process is a binding material, and the performance of the binding material directly influences the binding effect.
The medical bandaging materials in the prior art are various, and can effectively treat wounds and pain parts, wherein the most representative one is a medical bandage, and the materials of the medical bandage comprise an all-cotton plain weave, a wrinkle elastic bandage, an ammonia-silk elastic bandage, a PBT elastic bandage, an all-cotton gauze selvage bandage and a viscose plaster bandage. Most of the existing binding materials do not have antibacterial performance, are easy to cause infection of affected parts, and the hemostatic effect of the existing binding materials needs to be further improved.
In order to achieve the purpose of antibiosis, a certain amount of antibacterial agent is often required to be added in the processing of the medical binding material in the prior art so as to achieve the antibacterial effect and protect the affected part from infection. The existing antibacterial agent mostly adopts chemical reagents for disinfection and sterilization, can play a certain role, but also causes the problems of easy allergy, quick efficiency reduction and the like, improves the dosage of the antibacterial agent, has low degradation rate, and is unfavorable for resource utilization and environmental protection. And the added antibacterial agent has poor compatibility with the wrapping material base material, which often causes the defect of poor performance stability.
Therefore, in the field of medical dressing materials, there is a need for a dressing material that is waterproof, breathable and helpful for wound healing.
Disclosure of Invention
The invention aims to provide a production process of an ultrahigh-filtration medical breathable bag which is beneficial to healing, so that medical wrapping cloth is not only beneficial to wound healing, but also good in waterproofness and breathability, and the problems in the background art are solved.
In order to achieve the purpose, the invention provides the following technical scheme: a production process of an ultrahigh-filtration medical breathable bag for healing comprises the following steps:
s1, preparing an outer coating reagent;
firstly, selecting 40-70 parts of diphenylmethane diisocyanate, 50-80 parts of polyester polyol, 4-8 parts of a cross-linking agent, 2-4 parts of an antioxidant, 1-3 parts of organic silicon and 220-260 parts of methyl ethyl ketone according to parts by weight;
secondly, mixing and stirring the selected raw materials, and then adding the raw materials into a reaction kettle to perform a first-stage heating reaction to obtain a primary product;
thirdly, adding 6-12 parts by weight of 1, 4-butanediol into the primary product, mixing and stirring, and then carrying out a second-stage heating reaction to obtain a secondary product;
finally, adding 1 part by weight of catalyst, 5-10 parts by weight of diphenylmethane diisocyanate and 2-5 parts by weight of auxiliary agent into the secondary product, and uniformly stirring and mixing the mixture to obtain a finished product of the external coating reagent;
s2, cutting the rectangular elastic non-woven fabric, coating the finished product of the external coating reagent on the bottom surface of the elastic non-woven fabric, and drying;
s3, manufacturing a sterilizing sponge frame;
cutting a rectangular frame-shaped sponge, immersing the sponge into a sterilizing agent, and then drying to obtain a sterilizing sponge frame;
s4, adhering the gelatin sponge block to the center of the top surface of the elastic non-woven fabric, and adhering the sterilizing sponge frame to the periphery of the gelatin sponge block;
and S5, coating the glue solution on the rest part of the top surface of the elastic non-woven fabric, and attaching the film to the top surface of the elastic non-woven fabric to completely seal the top surface of the elastic non-woven fabric, thereby obtaining a finished product of the wrapping cloth.
Preferably, the antioxidant in the raw material selected in the step S1 is the antioxidant PUA-102.
Preferably, the heating temperature in the first-stage heating reaction and the second-stage heating reaction in the step S1 is 80 to 90 ℃, and the heating duration is 2 to 3 hours.
Preferably, the bactericidal agent used in step S3 is 6,6 '-difluoro-3, 3' -biimidazo [1,2-a ] pyridine and 5-hexanoyl-2-methyl-N-o-tolyl-3-carboxamide in a mass ratio of 4: 1 in the form of an aqueous pharmaceutical composition.
Preferably, the sponge is soaked in the sterilization agent for 30min when the sterilization sponge frame is manufactured in step S3, and a low-temperature drying method is adopted when the drying process is performed.
Preferably, both step S4 and step S5 are operated in a sterile environment.
Preferably, when the gelatin sponge block and the sterilizing sponge frame are adhered in the step S4, the glue solution is applied in a spot-coating manner.
Preferably, when the glue solution is applied in step S5, the edge of the top surface of the elastic nonwoven fabric is coated by a continuous coating method, and the glue solution is applied to the position of the elastic nonwoven fabric near the periphery of the sterilizing sponge frame by a spot coating method.
Preferably, the width of the glue solution continuously applied to the outer edge of the top surface of the elastic nonwoven fabric in the step S5 is 1.5 to 2 mm.
Preferably, in the step S5, when the top surface of the elastic non-woven fabric is coated with glue by a spot coating method at a position close to the periphery of the sterilizing sponge frame, the glue spots are arranged in a rectangular array, and the distance between adjacent glue spots is 0.1-0.2 mm.
Compared with the prior art, the invention has the beneficial effects that:
1. the invention relates to a medical binding material, which has lower operation and storage cost in the manufacturing process, greatly saves the production cost and is more environment-friendly in the manufacturing process.
2. The medical binding material manufactured by the processing technology has excellent waterproofness and air permeability.
3. The medical binding material prepared by the processing technology has the effect of promoting wound healing through the gelatin sponge block, and the sterilizing sponge frame at the periphery of the gelatin sponge block not only can play a role in sterilizing, but also can further prevent bacteria from entering a wound position to cause infection.
Drawings
Fig. 1 is a schematic structural view of the medical dressing cloth of the present invention.
In the figure: 1-elastic non-woven fabric; 2, covering a film; 3-gelatin sponge block; 4-sterilizing sponge frame.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example (b): referring to fig. 1, a process for producing an ultra-high-filtration medical breathable bag for healing comprises the following steps:
s1, preparing an outer coating reagent;
firstly, selecting 40-70 parts of diphenylmethane diisocyanate, 50-80 parts of polyester polyol, 4-8 parts of a cross-linking agent, 2-4 parts of an antioxidant, 1-3 parts of organic silicon and 220-260 parts of methyl ethyl ketone according to parts by weight;
wherein the antioxidant is antioxidant PUA-102.
Secondly, mixing and stirring the selected raw materials, and then adding the raw materials into a reaction kettle to perform a first-stage heating reaction to obtain a primary product;
thirdly, adding 6-12 parts by weight of 1, 4-butanediol into the primary product, mixing and stirring, and then carrying out a second-stage heating reaction to obtain a secondary product;
finally, adding 1 part by weight of catalyst, 5-10 parts by weight of diphenylmethane diisocyanate and 2-5 parts by weight of auxiliary agent into the secondary product, and uniformly stirring and mixing the mixture to obtain a finished product of the external coating reagent;
wherein the heating temperature in the first stage heating reaction and the second stage heating reaction is 80-90 ℃, and the heating duration is 2-3 h.
S2, cutting the rectangular elastic non-woven fabric 1, coating the finished product of the external coating reagent on the bottom surface of the elastic non-woven fabric 1 and drying;
s3, manufacturing a sterilizing sponge frame 4;
cutting a rectangular frame-shaped sponge, immersing the sponge into a sterilizing agent, and then drying to obtain a sterilizing sponge frame 4;
wherein the step is performed in a sterile environment; the bactericidal agent is 6,6 '-difluoro-3, 3' -biimidazo [1,2-a ] pyridine and 5-hexanoyl-2-methyl-N-o-tolyl-3-formamide according to the mass ratio of 4: 1 in water; the sponge is soaked in the sterilizing agent for 30min when the sterilizing sponge frame 4 is manufactured, and a low-temperature drying method is adopted when drying treatment is carried out.
S4, in an aseptic environment, adhering the gelatin sponge block 3 to the center of the top surface of the elastic non-woven fabric 1, and then adhering the sterilizing sponge frame 4 to the periphery of the gelatin sponge block 3;
wherein, when the gelatin sponge block 3 and the sterilizing sponge frame 4 are stuck, the glue solution is coated in a spot-coating mode.
S5, coating glue solution on the rest part of the top surface of the elastic non-woven fabric 1 in an aseptic environment, and attaching the film 2 to the top surface of the elastic non-woven fabric 1 to completely seal the top surface of the elastic non-woven fabric 1, thereby obtaining a finished bound fabric;
when glue solution is coated, the edge of the top surface of the elastic non-woven fabric 1 is coated by adopting a continuous coating method, and the width of the glue solution continuously coated at the outer edge position is 1.5-2 mm; and (3) coating the glue solution on the position, close to the periphery of the sterilizing sponge frame 4, of the elastic non-woven fabric 1 by adopting a point coating method, wherein when the glue is coated by adopting the point coating method, the glue spots are arranged in a rectangular array mode, and the distance between every two adjacent glue spots is 0.1-0.2 mm.
In the embodiments provided in the present invention, it should be understood that the disclosed system, apparatus and method may be implemented in other ways. For example, the above-described apparatus embodiments are merely illustrative, and for example, the division of the modules or units is only one logical division, and other divisions may be realized in practice, for example, a plurality of units or components may be combined or integrated into another system, or some features may be omitted, or not executed. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection through some interfaces, devices or units, and may be in an electrical, mechanical or other form.
The units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the embodiment.
In addition, functional units in the embodiments of the present invention may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit. The integrated unit can be realized in a form of hardware, and can also be realized in a form of a software functional unit.
The above description is only an embodiment of the present invention, and not intended to limit the scope of the present invention, and all modifications of equivalent structures and equivalent processes, which are made by the present specification, or directly or indirectly applied to other related technical fields, are included in the scope of the present invention.
Claims (10)
1. A production process of an ultrahigh-filtration medical breathable bag for healing is characterized by comprising the following steps:
s1, preparing an outer coating reagent;
firstly, selecting 40-70 parts of diphenylmethane diisocyanate, 50-80 parts of polyester polyol, 4-8 parts of a cross-linking agent, 2-4 parts of an antioxidant, 1-3 parts of organic silicon and 220-260 parts of methyl ethyl ketone according to parts by weight;
secondly, mixing and stirring the selected raw materials, and then adding the raw materials into a reaction kettle to perform a first-stage heating reaction to obtain a primary product;
thirdly, adding 6-12 parts by weight of 1, 4-butanediol into the primary product, mixing and stirring, and then carrying out a second-stage heating reaction to obtain a secondary product;
finally, adding 1 part by weight of catalyst, 5-10 parts by weight of diphenylmethane diisocyanate and 2-5 parts by weight of auxiliary agent into the secondary product, and uniformly stirring and mixing the mixture to obtain a finished product of the external coating reagent;
s2, cutting the rectangular elastic non-woven fabric (1), coating the finished product of the external coating reagent on the bottom surface of the elastic non-woven fabric (1) and drying;
s3, manufacturing a sterilizing sponge frame (4);
cutting a rectangular frame-shaped sponge, immersing the sponge into a sterilizing agent, and then drying to obtain a sterilizing sponge frame (4);
s4, sticking the gelatin sponge block (3) to the center of the top surface of the elastic non-woven fabric (1), and then sticking the sterilizing sponge frame (4) to the periphery of the gelatin sponge block (3);
and S5, coating the glue solution on the rest part of the top surface of the elastic non-woven fabric (1), and attaching the coating film (2) to the top surface of the elastic non-woven fabric (1) so as to completely seal the top surface of the elastic non-woven fabric (1), thereby obtaining a finished bound fabric.
2. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: in the step S1, the antioxidant in the raw material is selected as the antioxidant PUA-102.
3. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: in the step S1, the heating temperature in the first stage heating reaction and the second stage heating reaction is 80-90 ℃, and the heating duration is 2-3 h.
4. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: the bactericidal agent used in step S3 is 6,6 '-difluoro-3, 3' -biimidazo [1,2-a ] pyridine and 5-hexanoyl-2-methyl-N-o-tolyl-3-carboxamide in a mass ratio of 4: 1 in the form of an aqueous pharmaceutical composition.
5. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: in the step S3, the sponge is soaked in the sterilization agent for 30min when the sterilization sponge frame (4) is manufactured, and a low-temperature drying method is adopted when the drying treatment is performed.
6. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: both the step S4 and the step S5 operate in a sterile environment.
7. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: and when the gelatin sponge block (3) and the sterilizing sponge frame (4) are adhered in the step S4, applying glue solution in a spot coating mode.
8. The process for producing an ultra-high filtration medical air permeable bag for assisting healing according to claim 1, wherein: when the glue solution is coated in the step S5, the edge of the top surface of the elastic non-woven fabric (1) is coated by adopting a continuous coating method, and the glue solution is coated at the position, close to the periphery of the sterilizing sponge frame (4), of the elastic non-woven fabric (1) by adopting a point coating method.
9. The process for producing an ultra-high filtration medical air permeable pack for assisting healing according to claim 8, wherein: and in the step S5, the width of continuously coating glue solution on the outer edge of the top surface of the elastic non-woven fabric (1) is 1.5-2 mm.
10. The process for producing an ultra-high filtration medical air permeable pack for assisting healing according to claim 8, wherein: and S5, when the top surface of the elastic non-woven fabric (1) is coated with glue at a position close to the periphery of the sterilizing sponge frame (4) by a point coating method, the glue points are arranged in a rectangular array mode, and the distance between every two adjacent glue points is 0.1-0.2 mm.
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