CN207627486U - A kind of medical anti-scar dressing - Google Patents
A kind of medical anti-scar dressing Download PDFInfo
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- CN207627486U CN207627486U CN201720397138.9U CN201720397138U CN207627486U CN 207627486 U CN207627486 U CN 207627486U CN 201720397138 U CN201720397138 U CN 201720397138U CN 207627486 U CN207627486 U CN 207627486U
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Abstract
The utility model medical dressing technical field, and in particular to a kind of medical anti-scar dressing, the medical anti-scar dressing of the utility model include acellular dermal matrix layer, collagen hydrogels layer, liquid-adsorption layer successively from inside to outside；It is uniformly distributed on acellular dermal matrix layer to have the imbibing hole through entire acellular dermal matrix layer；It is uniformly distributed in collagen hydrogels layer to have anti-scar medicament microcapsule particle.Acellular dermal matrix layer provides the effective carrier that cell quickly divides, is proliferated, migrates, breaks up as 3D holders, promotes wound healing, prevent scar from generating；Wound fluid enters collagen hydrogels layer by imbibing hole, anti- scar medicament microcapsule particle ruptures dissolving under the action of diffusate, collagen hydrogels also gradually dissolving under the action of diffusate, microcapsule granule after rupture releases anti-scar drug, as dissolved gum original albumen is applied to wound from imbibing hole, auxiliary acellular dermal matrix layer further prevents the generation of scar.
Description
Technical field
A kind of the utility model medical dressing technical field, and in particular to medical anti-scar dressing.
Background technology
It is exactly timely progress antibacterial anti-infection processing that surgical wound is most important after occurring.It is carried out using medical dressing class
Wound dressing processing is common therapeutic modality, and wound can be made to be influenced from bacterium infection and foeign element, plays protection wound
Mouthful, the effect of wound repairing.Early stage is mainly gauze dressing, and for such material without water proofing property, isolation performance is poor, causes wound viscous
Even.There is a series of efficient, the novel high-molecular biologic dressing such as hydrogel, hydrocolloid, carbon fiber in later stage, but these are produced
Or product major part structure it is single or can only absorb wound exudate, can only antibacterial disappear pain, particularly with wound promotion heal
Function and anti-scar function need to improve.
Acellular dermal matrix be used for wound when 3D holders can be provided for wound, provide cell quickly divide, be proliferated,
The effective carrier of migration, differentiation, to have certain anti-scar effect, in consideration of it, occurring using acellular dermal matrix
The dressing of making, but simple de- cell skin-grafting matrix can not absorb a large amount of wound exudate, cause frequent more change dressings
Problem.In order to solve this problem, it is studied and has been improved for the structure of the dressing based on acellular dermal matrix, such as China
Patent CN203138856U discloses a kind of novel dermal matrix wound protecting system, including Xenogenic acellular dermal matrix or contains antibacterial
The Xenogenic acellular dermal matrix of ingredient, in Xenogenic acellular dermal matrix or containing the Xenogenic acellular dermal matrix of antimicrobial component
Outer surface covers medical activated carbon functional dressings, and polyurethane is arranged outside medical activated carbon functional dressings, is arranged outside polyurethane
Carry out the Wound-surface negative pressure drainage mechanism of negative pressure drainage to the surface of a wound, the dressing structure of the disclosure be by by negative pressure drainage machine is set outside
Structure realizes the imbibition drainage to the surface of a wound, complicated, and simple anti-scar effect by acellular dermal matrix
Actual clinical demand is cannot be satisfied, needs further to be improved.
Invention content
In order to overcome the deficiencies of existing technologies, the purpose of this utility model is to provide a kind of medical anti-scar dressing, has
Significant promoting healing, anti-scar effect, can quickly absorb sepage, keep wound wet environment, adhesion wound.
In order to achieve the goal above, the utility model adopts the following technical solution：
A kind of medical anti-scar dressing includes acellular dermal successively from inside to outside to contact one layer of wound as internal layer
Hypothallus, collagen hydrogels layer, liquid-adsorption layer；It is uniformly distributed wherein on acellular dermal matrix layer to have through entirely de- cell
The imbibing hole of dermal matrix layer penetrated for wound fluid；It is uniformly distributed in collagen hydrogels layer to have anti-scar drug micro-
Capsule particle.
Optionally, the size of the acellular dermal matrix layer and liquid-adsorption layer is all higher than collagen hydrogels layer.
In order to balance acellular dermal matrix layer well through diffusate and the intensity of its own and to wound cell
The quickly 3D holders effect of division, proliferation, migration, differentiation, optionally, the imbibing hole being arranged on the acellular dermal matrix layer
The circular hole for being 3 ~ 8mm for aperture, porosity are 20 ~ 50%.
Optionally, it is additionally provided with waterproof material film layer outside the liquid-adsorption layer.Assign the good waterproof action of dressing.
Optionally, the waterproof material film layer is polyurethane water-proof breathable film layer.
Optionally, the size of the waterproof material film layer is greater than or equal to liquid-adsorption layer.
Optionally, the acellular dermal matrix layer internal layer is additionally provided with release film layer.Release film layer has anti-well
Dirt acts on, and avoids being contaminated in the acellular dermal matrix layer packed be in direct contact wound in transportational process.
Optionally, the size of the release film layer is greater than or equal to acellular dermal matrix layer.
Optionally, the acellular dermal matrix layer is the acellular dermal matrix layer that load has antimicrobial component.It assigns and applying
Expect good antibiotic effect.
Simultaneously as nano silver class anti-biotic material, which is easy metabolism, enters body-internal-circulation system, state food drug surveilance pipe
General bureau is managed by such material not as the scope of medical instrument management, above-mentioned load has the acellular dermal matrix of antimicrobial component
Layer is that acellular dermal matrix is immersed in the antibacterial containing antimicrobial components such as poly (hexamethylene) hydrochloride, organosilicon quaternary ammonium salts
It is prepared in liquid；A concentration of the 0.02 ~ 0.5% of poly (hexamethylene) hydrochloride wherein in antimicrobial fluid, organosilicon quaternary ammonium salt it is dense
Degree is 0.1 ~ 2.0%.
Optionally, the liquid-adsorption layer is active-carbon fibre material layer or alginate fiber material layer or polyurethane foam material
The bed of material.
Optionally, the thickness of the waterproof material film layer is 0.1 ~ 0.3mm；The thickness of the acellular dermal matrix layer
For 0.18 ~ 0.45mm；The thickness of the collagen hydrogels layer is 1 ~ 3mm；The thickness of the liquid-adsorption layer is 3 ~ 5mm.
Optionally, the raw material that the acellular dermal matrix layer uses is pigskin, sheepskin or ox-hides.
Optionally, above-mentioned anti-scar dressing, between waterproof material film layer and liquid-adsorption layer, liquid-adsorption layer and collagen water-setting
It is bonded using acrylic acid adhesive between glue-line, between collagen hydrogels layer and acellular dermal matrix layer.
The medical anti-scar dressing of the utility model, is disposed with the acellular dermal base for being laid with imbibing hole from inside to outside
Matter layer, inner homogeneous are laid with the collagen hydrogels layer and liquid-adsorption layer of anti-scar medicament microcapsule particle, have beneficial below
Effect：
1）Acellular dermal matrix layer is in direct contact wound, quickly divide, be proliferated as 3D holders offer cell, migrating,
The effective carrier of differentiation promotes wound healing, prevents scar from generating to a certain extent；Further, the utility model also exists
The antimicrobial components such as poly (hexamethylene) hydrochloride and organosilicon quaternary ammonium salt are loaded on acellular dermal matrix layer, can be effectively prevent
The proliferation of wound surface pathogenic microorganisms, prevents wound infection；
2）Wound fluid enters collagen hydrogels layer by imbibing hole, and what is mixed in collagen hydrogels layer is anti-
Scar medicament microcapsule particle ruptures gradual dissolving under the action of diffusate, and collagen hydrogels are under the action of diffusate
Gradually dissolving, the microcapsule granule after rupture releases anti-scar drug, as dissolved gum original albumen is applied to wound from imbibing hole
At mouthful, auxiliary acellular dermal matrix layer further prevents the generation of scar；Meanwhile containing in collagen hydrogels layer
Moisture can keep wound surface to have the environment of wetting, promote the healing of wound, prevent adhesion；
3）Liquid-adsorption layer is arranged in the outer layer of collagen hydrogels layer, can quickly absorb extra diffusate, avoid oozing
Go out pollution of the liquid to wound；Liquid-adsorption layer being capable of blocks dust and bacterium simultaneously；
4）Further, the size of the liquid-adsorption layer of the utility model dressing and acellular dermal matrix layer is all higher than glue
Former protein hydrogel layer forms and collagen hydrogels layer is folded in intermediate structure, realizes to collagen hydrogels layer
Ring protection effect, avoid that collagen hydrogels dissolve and its internal microcapsule granule laid is encountering diffusate rupture
Release is overflowed outward.
Description of the drawings
Fig. 1 is the overall structure diagram for the medical anti-scar dressing that the utility model embodiment provides.
Specific implementation mode
A kind of medical anti-scar dressing includes successively from inside to outside as shown in Figure 1, to contact one layer of wound as internal layer
Acellular dermal matrix layer 1, collagen hydrogels layer 2, liquid-adsorption layer 4；It is wherein uniformly distributed on acellular dermal matrix layer 1 to have
Through the imbibing hole 7 of entire acellular dermal matrix layer penetrated for wound fluid；Uniform cloth in collagen hydrogels layer 2
Equipped with anti-scar medicament microcapsule particle 3.
Optionally, the raw material that acellular dermal matrix layer 1 uses in the present embodiment can be pigskin, sheepskin or ox-hide.
Acellular dermal matrix layer is in direct contact wound, and 3D holders can be used as to provide cell and quickly divide, be proliferated, move
It moves, the effective carrier of differentiation, promotes wound healing, place the generation of scar to a certain extent；Wound fluid passes through imbibition
Hole enters collagen hydrogels layer, and the anti-scar microcapsule granule mixed in collagen hydrogels layer is under the action of diffusate
Dissolving rupture, releases drug ingedient, while collagen hydrogels also dissolve under the action of diffusate, dissolved gum original egg
This drug ingedient is carried in vain, wound is applied to by imbibing hole, promote the anti-scar effect of dressing；Meanwhile collagen water-setting
The moisture that glue-line contains can keep wound to be in suitable wet environment, avoid generating adhesion；The liquid-adsorption layer of outer layer can be fast
The sepage that the absorption of speed is more than avoids sepage dipping skin and the pollution to wound.
Further, in order to form protective effect to collagen hydrogel layer, the collagen egg for the ingredient for carrying drug is avoided
Plain boiled water gel layer overflows outward upon dissolution, as shown in Figure 1, acellular dermal matrix layer 1 and liquid-adsorption layer 4 in the present embodiment dressing
Size be all higher than collagen hydrogels layer 2, ring protection is formed to it.
In order to balance acellular dermal matrix layer well through diffusate and the intensity of its own and to wound cell
It quickly divides, proliferation, migrate, the effect of the 3D holders of differentiation, the imbibing hole being arranged on acellular dermal matrix layer 1 in the present embodiment
The circular hole for being 3 ~ 8mm for aperture, porosity 30%.It should be noted that porosity is only to preferred embodiment in the present embodiment
One distance illustrates that the porosity on the acellular dermal matrix layer 1 of the utility model dressing can be 20 ~ 50%.
In order to make dressing that there is better water proof and dust proof effect, as shown in Figure 1, being additionally provided with outside the present embodiment liquid-adsorption layer 4
Waterproof material film layer 6, it is further preferred that the material that waterproof material film layer 6 uses is polyurethane water-proof breathable films.
As shown in Figure 1, the size of waterproof material film layer 6 is more than liquid-adsorption layer 4.It should be noted waterproof material film layer
6 be for protecting entire dressing to make it have good water resistance, therefore 6 need of waterproof material film layer can cover imbibition
Layer 4, i.e. the size of waterproof material film layer 6 can also be equal to liquid-adsorption layer 4.
In order to avoid forming pollution to the acellular dermal matrix layer for being in direct contact wound in packaging and transportational process, such as
Shown in Fig. 1,1 internal layer of acellular dermal matrix layer is additionally provided with release film layer 5 in the present embodiment.The size of release film layer 5 is more than
Acellular dermal matrix layer 1.It should be noted that release film layer 5 is to protect acellular dermal matrix layer 1 to avoid by dirt
Dye, as long as therefore release film layer 5 size be not less than acellular dermal matrix layer 1.
The anti-scar dressing of the present embodiment, between waterproof material film layer and liquid-adsorption layer, liquid-adsorption layer and collagen hydrogels
It is bonded using acrylic acid adhesive between layer, between collagen hydrogels layer and acellular dermal matrix layer.
Optionally, in order to promote the whole anti-microbial property of dressing, the acellular dermal matrix layer 1 of the utility model dressing is
Load has the acellular dermal matrix layer of antimicrobial component.
Simultaneously as nano silver class anti-biotic material, which is easy metabolism, enters body-internal-circulation system, state food drug surveilance pipe
General bureau is managed by such material not as the scope of medical instrument management, the present embodiment loads the acellular dermal for having antimicrobial component
Hypothallus is that acellular dermal matrix is immersed in containing antimicrobial components such as poly (hexamethylene) hydrochloride, organosilicon quaternary ammonium salts
It is prepared in antimicrobial fluid；A concentration of the 0.02 ~ 0.5% of poly (hexamethylene) hydrochloride, organosilicon quaternary ammonium salt wherein in antimicrobial fluid
A concentration of 0.1 ~ 2.0%.
As shown in Figure 1, the present embodiment liquid-adsorption layer 4 is polyurethane foam layer.It should be noted that being adopted in the present embodiment
With polyurethane foam layer it is to one of the utility model dressing for example, liquid-adsorption layer 4 can also be used such as activity
The material for the liquid suction function that carbon fibre material or alginate fiber material etc. have had
As shown in Figure 1, the thickness of waterproof material film layer 6 is 0.2mm in the present embodiment；Acellular dermal matrix layer 1
Thickness is 0.30mm；The thickness of collagen hydrogels layer 2 is 2mm；4 thickness of liquid-adsorption layer is 4mm.It should be noted this implementation
The thickness size of each functional layer is the preferred embodiment of the utility model dressing structure in example dressing, and not enough this practicality is new in pairs
The specific restriction of type dressing structure, the thickness of waterproof material film layer can be 0.1 ~ 0.3mm in the utility model dressing；It is de- thin
The thickness of born of the same parents' dermal matrix layer can be 0.18 ~ 0.45mm；The thickness of collagen hydrogels layer can be 1 ~ 3mm；Liquid-adsorption layer
Thickness can be 3 ~ 5mm.
Claims (10)
1. a kind of medical anti-scar dressing, which is characterized in that include de- successively from inside to outside to contact one layer of wound as internal layer
Acellular dermal matrix layer, collagen hydrogels layer, liquid-adsorption layer；It is wherein uniformly distributed on acellular dermal matrix layer to have through whole
The imbibing hole of a acellular dermal matrix layer penetrated for wound fluid；It is uniformly distributed in collagen hydrogels layer to have anti-scar
Trace medicament microcapsule particle.
2. medical anti-scar dressing as described in claim 1, which is characterized in that the acellular dermal matrix layer and liquid-adsorption layer
Size be all higher than collagen hydrogels layer.
3. medical anti-scar dressing as claimed in claim 1 or 2, which is characterized in that set on the acellular dermal matrix layer
The imbibing hole set is the circular hole that aperture is 3 ~ 8mm, and porosity is 20 ~ 50%.
4. medical anti-scar dressing as claimed in claim 1 or 2, which is characterized in that be additionally provided with waterproof outside the liquid-adsorption layer
Material film layers.
5. medical anti-scar dressing as claimed in claim 4, which is characterized in that the size of the waterproof material film layer is more than
Or it is equal to liquid-adsorption layer.
6. medical anti-scar dressing as claimed in claim 1 or 2, which is characterized in that the acellular dermal matrix layer internal layer
It is additionally provided with release film layer.
7. medical anti-scar dressing as claimed in claim 6, which is characterized in that the size of the release film layer is greater than or equal to
Acellular dermal matrix layer.
8. medical anti-scar dressing as claimed in claim 1 or 2, which is characterized in that the acellular dermal matrix layer is negative
It is loaded with the acellular dermal matrix layer of antimicrobial component.
9. medical anti-scar dressing as claimed in claim 1 or 2, which is characterized in that the liquid-adsorption layer is activated carbon fiber material
The bed of material or alginate fiber material layer or polyurethane foam layer.
10. medical anti-scar dressing as claimed in claim 4, which is characterized in that the thickness of the waterproof material film layer is
0.1~0.3mm；The thickness of the acellular dermal matrix layer is 0.18 ~ 0.45mm；The thickness of the collagen hydrogels layer
For 1 ~ 3mm；The thickness of the liquid-adsorption layer is 3 ~ 5mm.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720397138.9U CN207627486U (en) | 2017-04-17 | 2017-04-17 | A kind of medical anti-scar dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201720397138.9U CN207627486U (en) | 2017-04-17 | 2017-04-17 | A kind of medical anti-scar dressing |
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| Publication Number | Publication Date |
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| CN207627486U true CN207627486U (en) | 2018-07-20 |
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| CN201720397138.9U Active CN207627486U (en) | 2017-04-17 | 2017-04-17 | A kind of medical anti-scar dressing |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112155838A (en) * | 2020-10-23 | 2021-01-01 | 广东美贝健药业有限公司 | Honeysuckle subsides of bringing down a fever |
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2017
- 2017-04-17 CN CN201720397138.9U patent/CN207627486U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112155838A (en) * | 2020-10-23 | 2021-01-01 | 广东美贝健药业有限公司 | Honeysuckle subsides of bringing down a fever |
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