CN113994973A - Potassium monopersulfate microencapsulated compound disinfectant and production process thereof - Google Patents
Potassium monopersulfate microencapsulated compound disinfectant and production process thereof Download PDFInfo
- Publication number
- CN113994973A CN113994973A CN202111307262.9A CN202111307262A CN113994973A CN 113994973 A CN113994973 A CN 113994973A CN 202111307262 A CN202111307262 A CN 202111307262A CN 113994973 A CN113994973 A CN 113994973A
- Authority
- CN
- China
- Prior art keywords
- potassium monopersulfate
- substance
- potassium
- auxiliary material
- disinfectant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000012425 OXONE® Substances 0.000 title claims abstract description 87
- HJKYXKSLRZKNSI-UHFFFAOYSA-I pentapotassium;hydrogen sulfate;oxido sulfate;sulfuric acid Chemical compound [K+].[K+].[K+].[K+].[K+].OS([O-])(=O)=O.[O-]S([O-])(=O)=O.OS(=O)(=O)O[O-].OS(=O)(=O)O[O-] HJKYXKSLRZKNSI-UHFFFAOYSA-I 0.000 title claims abstract description 79
- 239000000645 desinfectant Substances 0.000 title claims abstract description 51
- 150000001875 compounds Chemical class 0.000 title claims abstract description 30
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 14
- 239000000463 material Substances 0.000 claims abstract description 78
- 150000003839 salts Chemical class 0.000 claims abstract description 43
- 239000002131 composite material Substances 0.000 claims abstract description 39
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 25
- 239000011248 coating agent Substances 0.000 claims abstract description 21
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims abstract description 15
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229910052794 bromium Inorganic materials 0.000 claims abstract description 15
- 238000009792 diffusion process Methods 0.000 claims abstract description 15
- 239000003086 colorant Substances 0.000 claims abstract description 14
- 239000000945 filler Substances 0.000 claims abstract description 14
- 239000003381 stabilizer Substances 0.000 claims abstract description 14
- -1 potassium monopersulfate compound Chemical class 0.000 claims abstract description 12
- 239000000126 substance Substances 0.000 claims description 36
- 239000007888 film coating Substances 0.000 claims description 14
- 238000009501 film coating Methods 0.000 claims description 14
- 238000000576 coating method Methods 0.000 claims description 12
- 238000001035 drying Methods 0.000 claims description 12
- OMOVVBIIQSXZSZ-UHFFFAOYSA-N [6-(4-acetyloxy-5,9a-dimethyl-2,7-dioxo-4,5a,6,9-tetrahydro-3h-pyrano[3,4-b]oxepin-5-yl)-5-formyloxy-3-(furan-3-yl)-3a-methyl-7-methylidene-1a,2,3,4,5,6-hexahydroindeno[1,7a-b]oxiren-4-yl] 2-hydroxy-3-methylpentanoate Chemical compound CC12C(OC(=O)C(O)C(C)CC)C(OC=O)C(C3(C)C(CC(=O)OC4(C)COC(=O)CC43)OC(C)=O)C(=C)C32OC3CC1C=1C=COC=1 OMOVVBIIQSXZSZ-UHFFFAOYSA-N 0.000 claims description 9
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical group OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- QAYICIQNSGETAS-UHFFFAOYSA-N dazomet Chemical compound CN1CSC(=S)N(C)C1 QAYICIQNSGETAS-UHFFFAOYSA-N 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 8
- 230000003204 osmotic effect Effects 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 7
- 230000035515 penetration Effects 0.000 claims description 7
- JTNCEQNHURODLX-UHFFFAOYSA-N 2-phenylethanimidamide Chemical compound NC(=N)CC1=CC=CC=C1 JTNCEQNHURODLX-UHFFFAOYSA-N 0.000 claims description 6
- 235000005979 Citrus limon Nutrition 0.000 claims description 6
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 6
- 238000009835 boiling Methods 0.000 claims description 6
- AMXOYNBUYSYVKV-UHFFFAOYSA-M lithium bromide Chemical compound [Li+].[Br-] AMXOYNBUYSYVKV-UHFFFAOYSA-M 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 229910000343 potassium bisulfate Inorganic materials 0.000 claims description 6
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 claims description 6
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 claims description 6
- 229910052939 potassium sulfate Inorganic materials 0.000 claims description 6
- 235000011151 potassium sulphates Nutrition 0.000 claims description 6
- 239000011734 sodium Substances 0.000 claims description 6
- 229910052708 sodium Inorganic materials 0.000 claims description 6
- JHJLBTNAGRQEKS-UHFFFAOYSA-M sodium bromide Chemical compound [Na+].[Br-] JHJLBTNAGRQEKS-UHFFFAOYSA-M 0.000 claims description 6
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims description 6
- 239000002671 adjuvant Substances 0.000 claims description 4
- MENYRYNFSIBDQN-UHFFFAOYSA-N 5,5-dibromoimidazolidine-2,4-dione Chemical compound BrC1(Br)NC(=O)NC1=O MENYRYNFSIBDQN-UHFFFAOYSA-N 0.000 claims description 3
- SGHZXLIDFTYFHQ-UHFFFAOYSA-L Brilliant Blue Chemical compound [Na+].[Na+].C=1C=C(C(=C2C=CC(C=C2)=[N+](CC)CC=2C=C(C=CC=2)S([O-])(=O)=O)C=2C(=CC=CC=2)S([O-])(=O)=O)C=CC=1N(CC)CC1=CC=CC(S([O-])(=O)=O)=C1 SGHZXLIDFTYFHQ-UHFFFAOYSA-L 0.000 claims description 3
- 235000005976 Citrus sinensis Nutrition 0.000 claims description 3
- 240000002319 Citrus sinensis Species 0.000 claims description 3
- 229920000858 Cyclodextrin Polymers 0.000 claims description 3
- 239000001116 FEMA 4028 Substances 0.000 claims description 3
- 239000004115 Sodium Silicate Substances 0.000 claims description 3
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 3
- DDAQLPYLBPPPRV-UHFFFAOYSA-N [4-(hydroxymethyl)-2-oxo-1,3,2lambda5-dioxaphosphetan-2-yl] dihydrogen phosphate Chemical compound OCC1OP(=O)(OP(O)(O)=O)O1 DDAQLPYLBPPPRV-UHFFFAOYSA-N 0.000 claims description 3
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims description 3
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims description 3
- 229960004853 betadex Drugs 0.000 claims description 3
- 235000012730 carminic acid Nutrition 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 3
- 239000003205 fragrance Substances 0.000 claims description 3
- 238000005469 granulation Methods 0.000 claims description 3
- 230000003179 granulation Effects 0.000 claims description 3
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 3
- 239000001095 magnesium carbonate Substances 0.000 claims description 3
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 3
- 235000014380 magnesium carbonate Nutrition 0.000 claims description 3
- 239000000395 magnesium oxide Substances 0.000 claims description 3
- CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims description 3
- 235000012245 magnesium oxide Nutrition 0.000 claims description 3
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 3
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 3
- AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 3
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims description 3
- GCLGEJMYGQKIIW-UHFFFAOYSA-H sodium hexametaphosphate Chemical compound [Na]OP1(=O)OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])OP(=O)(O[Na])O1 GCLGEJMYGQKIIW-UHFFFAOYSA-H 0.000 claims description 3
- 235000019982 sodium hexametaphosphate Nutrition 0.000 claims description 3
- 229940048086 sodium pyrophosphate Drugs 0.000 claims description 3
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 3
- 229910052911 sodium silicate Inorganic materials 0.000 claims description 3
- 235000019794 sodium silicate Nutrition 0.000 claims description 3
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 3
- 235000011152 sodium sulphate Nutrition 0.000 claims description 3
- IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid group Chemical group S(N)(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 claims description 3
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims description 3
- 244000248349 Citrus limon Species 0.000 claims 2
- XTOQOJJNGPEPMM-UHFFFAOYSA-N o-(2-oxo-1,3,2$l^{5}-dioxaphosphinan-2-yl)hydroxylamine Chemical compound NOP1(=O)OCCCO1 XTOQOJJNGPEPMM-UHFFFAOYSA-N 0.000 claims 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 15
- 239000000047 product Substances 0.000 abstract description 6
- 230000007794 irritation Effects 0.000 abstract description 4
- 230000035945 sensitivity Effects 0.000 abstract description 4
- 238000010521 absorption reaction Methods 0.000 abstract description 3
- 238000005054 agglomeration Methods 0.000 abstract description 2
- 230000002776 aggregation Effects 0.000 abstract description 2
- 239000006227 byproduct Substances 0.000 abstract description 2
- 230000000711 cancerogenic effect Effects 0.000 abstract description 2
- 231100000315 carcinogenic Toxicity 0.000 abstract description 2
- 230000000149 penetrating effect Effects 0.000 abstract 1
- 230000001550 time effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 13
- 230000008569 process Effects 0.000 description 6
- 244000131522 Citrus pyriformis Species 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 4
- 230000002147 killing effect Effects 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 230000001590 oxidative effect Effects 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- FDGBQHCDMSYZRC-UHFFFAOYSA-N 2-hydroxy-2-oxo-1,3,2$l^{5}-dioxaphosphinan-4-amine Chemical compound NC1CCOP(O)(=O)O1 FDGBQHCDMSYZRC-UHFFFAOYSA-N 0.000 description 2
- 244000063299 Bacillus subtilis Species 0.000 description 2
- 235000014469 Bacillus subtilis Nutrition 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- CUILPNURFADTPE-UHFFFAOYSA-N hypobromous acid Chemical compound BrO CUILPNURFADTPE-UHFFFAOYSA-N 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- CIDGKBCDYFUZNN-UHFFFAOYSA-N sulfinylmethanone Chemical compound O=C=S=O CIDGKBCDYFUZNN-UHFFFAOYSA-N 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 description 1
- LFZAXBDWELNSEE-UHFFFAOYSA-N [S].[K] Chemical compound [S].[K] LFZAXBDWELNSEE-UHFFFAOYSA-N 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- CEJLBZWIKQJOAT-UHFFFAOYSA-N dichloroisocyanuric acid Chemical compound ClN1C(=O)NC(=O)N(Cl)C1=O CEJLBZWIKQJOAT-UHFFFAOYSA-N 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 239000011812 mixed powder Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- USHAGKDGDHPEEY-UHFFFAOYSA-L potassium persulfate Chemical compound [K+].[K+].[O-]S(=O)(=O)OOS([O-])(=O)=O USHAGKDGDHPEEY-UHFFFAOYSA-L 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
- A01N25/28—Microcapsules or nanocapsules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/02—Sulfur; Selenium; Tellurium; Compounds thereof
Abstract
The invention belongs to the technical field of disinfectants, and particularly relates to a potassium monopersulfate microencapsulated compound disinfectant and a production process thereof, wherein the potassium monopersulfate compound disinfectant is composed of a main material and an auxiliary material, the main material is potassium monopersulfate composite salt, and the auxiliary material is mainly composed of a bromine-containing compound, a stabilizer, a diffusion penetrating agent, a filling agent, a coloring agent, essence and a coating agent and is processed by the microencapsulation production process. The invention not only improves the disinfection capability of the potassium monopersulfate composite salt, but also does not generate carcinogenic disinfection by-products; the stability and the quality guarantee period of the potassium monopersulfate composite salt are increased, and the sensitivity of the potassium monopersulfate composite salt to humidity and temperature is reduced; has the advantages of good quick action, long time effect, small irritation, difficult agglomeration of finished products, moisture absorption and bag expansion.
Description
Technical Field
The invention belongs to the technical field of disinfectants, and particularly relates to a potassium monopersulfate microencapsulated compound disinfectant and a production process thereof.
Background
Potassium monopersulfate has become popular as a green, safe and efficient disinfectant in recent years. At present, the main research at home and abroad is mainly based on the complex disinfectant of potassium monopersulfate and sodium chloride or sodium dichloroisocyanurate, and the reaction principle is as follows: KHS2O8+NaCl
H2O + Cl2The disinfectant easily generates chloroform carcinogenic disinfection byproducts to cause secondary pollution, experts in the production process of the potassium monopersulfate pay less attention at home and abroad, and the traditional potassium monopersulfate compound salt has strong sensitivity to humidity and temperature and has the problems of large irritation and taste of products, easy caking, moisture absorption and bag expansion.
Disclosure of Invention
The invention aims to provide the microencapsulated compound disinfectant of the potassium monopersulfate compound salt, which has the advantages of good quick disinfection effect, long timeliness, no secondary pollution, difficult agglomeration, moisture absorption and bag expansion of a finished product, and a production process thereof. The invention relates to a method for producing hypobromous acid by reacting potassium monopersulfate with a bromine-containing compound, which has the following reaction principle: KHS2O8+ X-Br
HBrO, which is known to have a sterilizing power much higher than that of chlorine gas and hypochlorous acid, is relatively mild and does not generate carcinogens and cause secondary pollution, compared to chlorine gas and hypochlorous acid.
In order to achieve the purpose, the invention provides the following technical scheme: the potassium monopersulfate microencapsulated compound disinfectant consists of a main material and an auxiliary material, wherein the main material is potassium monopersulfate composite salt, and the auxiliary material mainly consists of a bromine-containing compound, a stabilizer, a penetration diffusion agent, a filler, a colorant, essence and a coating agent.
Preferably, the potassium monopersulfate composite salt consists of potassium monopersulfate, potassium bisulfate and potassium sulfate, and the molar ratio of the potassium monopersulfate to the potassium bisulfate to the potassium sulfate is 2: 1: 1.
preferably, the bromine-containing compound in the auxiliary material consists of a substance A and a substance B, wherein the substance A is dibromohydantoin, the substance B is one of potassium bromide, sodium bromide and lithium bromide, and the weight part ratio of the substance A to the substance B is (0-1) to (1-5).
Preferably, the stabilizer in the auxiliary material consists of a substance C, a substance D and a substance E, wherein the substance C is hydroxyethylidene diphosphate or aminotrimethylene phosphate, the substance D is sodium pyrophosphate or sodium hexametaphosphate, and the substance E is sulfamic acid or citric acid; the weight ratio of the substance C to the substance D to the substance E is 1: (2-5): (2-5).
Preferably, the osmotic diffusion agent in the auxiliary material comprises the thiazone and the alpha-sodium alkenyl sulfonate, wherein the weight ratio of the thiazone to the alpha-sodium alkenyl sulfonate is 1: (2-10).
Preferably, the filler in the auxiliary materials consists of one or two of anhydrous sodium silicate, magnesium sulfate, magnesium carbonate, sodium sulfate and magnesium oxide; the coloring agent in the auxiliary material is one of carmine, brilliant blue, sunset red and lemon yellow; the essence in the auxiliary materials is one of lemon essence, sweet orange essence and flower fragrance essence; the film coating agent is any one of polyvinylpyrrolidone, PEG and beta-cyclodextrin.
Preferably, the potassium monopersulfate composite salt comprises, by weight, 10-60 parts of a bromine-containing compound, 10-30 parts of a stabilizer, 1-5 parts of a penetration and diffusion agent, 5-30 parts of a filler, 0.1-0.5 part of a colorant, 0.2-1 part of an essence and 0.5-3 parts of a film coating agent.
The invention also provides a production process of the potassium monopersulfate microencapsulated compound disinfectant, which specifically comprises the following steps:
s1: mixing the auxiliary materials, namely mixing the auxiliary materials according to a certain proportion to obtain a mixture A1;
s2: crushing auxiliary materials, namely feeding the mixture A1 prepared in the step S1 into a crusher to be crushed to enable the mesh number to reach more than 200 meshes, so as to obtain crushed auxiliary materials A2;
s3: crushing the main material, namely taking a certain amount of potassium monopersulfate composite salt according to a proportion, and crushing the potassium monopersulfate composite salt at a specific temperature to ensure that the mesh number reaches more than 200 meshes to obtain a crushed main material B1;
s4: coating, coating and drying, namely feeding the crushed auxiliary material A2 prepared in the step S2 into a vacuum boiling drying granulation device, adding atomized coating agent into the device, and coating, coating and drying the crushed auxiliary material A2 to obtain a dried auxiliary material A3, wherein the moisture content of the dried auxiliary material A3 is less than 0.5%;
s5, conveying the crushed auxiliary material B1 prepared in the step S3 into a vacuum boiling drying granulating device, adding an atomized film coating agent into the device, and performing film coating treatment on the potassium monopersulfate composite salt to dry the auxiliary material B2, wherein the moisture content of the dried auxiliary material B2 is less than 0.5%;
s6: mixing and packaging, adding the prepared adjuvant A3 and the prepared main material B3 into a stirrer in proportion, mixing completely, making into final product, and packaging.
Further, the temperature in the step S3 is 20 to 60 ℃.
Further, the temperature in the step S3 is 40 to 50 ℃.
Compared with the prior art, the invention has the beneficial effects that:
1. the strong oxidizing property (potential value of 1.85 v) of the potassium monopersulfate is utilized, free hydroxyl and sulfate radicals and nascent oxygen are liberated when the potassium monopersulfate meets water, the potassium monopersulfate can form a chain reaction with bromide ions, and hypobromous acid continuously generated and the potassium monopersulfate have a synergistic disinfection effect. The disinfectant has the advantages of good disinfection effect, small irritation and no toxic or side effect, and is one of green, safe and efficient disinfectants.
2. The potassium monopersulfate composite salt and the auxiliary materials are treated by a microencapsulation process to obtain the potassium monopersulfate microencapsulated complex disinfectant, and the potassium monopersulfate microencapsulated complex disinfectant prepared by microencapsulation has the following advantages: the microencapsulation treatment increases the stability of the potassium monopersulfate composite salt, reduces the sensitivity of the potassium monopersulfate composite salt to humidity and temperature, and ensures that the product is not easy to agglomerate, absorb moisture and expand bags.
3. The invention adopts the microencapsulation treatment process, which obviously improves the long-acting property of the potassium monopersulfate compound salt for disinfection; particularly, after the thiaketone is added, the potassium monopersulfate composite salt increases the penetration and diffusion capacity of the disinfectant, increases the continuous effectiveness and rapidness of the potassium monopersulfate composite salt, reduces the frequent input times of the disinfectant, and effectively protects susceptible animals.
Description of the drawings:
FIG. 1 is a flow chart of the production process of the present invention;
fig. 2 is a photograph of microencapsulated monopersulfate potassium hydrogen complex salt disinfectant (powder) under an electron microscope.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention. When an amount, concentration, or other value or parameter is expressed as a range, preferred range, or as a range of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when the range "1 to 5" is disclosed, the described range should be construed as including the ranges "1 to 4", "1 to 3", "1 to 2", "2 to 3" and "3 to 4", "4 to 5" and "3 to 5", etc. When a range of values is described herein, unless otherwise stated, the range is intended to include the endpoints thereof and all integers and fractions within the range.
Example 1
The embodiment provides the following technical scheme: the potassium monopersulfate compound salt compound disinfectant is a potassium monopersulfate microencapsulated compound disinfectant and comprises a main material and an auxiliary material, wherein the main material is potassium monopersulfate compound salt, and the auxiliary material mainly comprises a bromine-containing compound, a stabilizer, a penetration diffusion agent, a filler, a colorant, essence and a coating agent. Preferably, 10-60 parts of potassium monopersulfate composite salt, 1-70 parts of bromine-containing compound, 10-30 parts of stabilizer, 1-5 parts of osmotic diffusion agent, 5-30 parts of filler, 0.1-0.5 part of colorant, 0.2-1 part of essence and 0.5-3 parts of film coating agent.
Specifically, the following components, by weight, are 40 parts of oxone complex salt, 40 parts of a bromine-containing compound, 20 parts of a stabilizer, 2 parts of a diffusion penetration agent, 15 parts of a filler, 0.3 part of a colorant, 0.5 part of an essence, and 2 parts of a coating agent in this embodiment.
In a preferred embodiment of this embodiment, the oxone complex salt is composed of potassium monopersulfate, potassium bisulfate, and potassium sulfate, and the molar ratio of potassium monopersulfate, potassium bisulfate, and potassium sulfate is 2: 1: 1.
as a preferable embodiment scheme of the embodiment, the bromine-containing compound in the auxiliary material consists of a substance A and a substance B, wherein the substance A is dibromohydantoin, the substance B is one of potassium bromide, sodium bromide and lithium bromide, and the weight part ratio of the substance A to the substance B is (0-1) to (1-5).
As a preferable embodiment scheme of this embodiment, the stabilizer in the auxiliary material is composed of a substance C, a substance D, and a substance E, wherein the substance C is hydroxyethylidene diphosphate or aminotrimethylene phosphate, the substance D is sodium pyrophosphate or sodium hexametaphosphate, and the substance E is sulfamic acid or citric acid; the weight ratio of the substance C to the substance D to the substance E is 1: (2-5): (2-5).
As a preferable embodiment scheme of this embodiment, the osmotic diffusion agent in the auxiliary material includes thiazone and sodium alpha-alkenyl sulfonate, wherein the weight ratio of the thiazone to the sodium alpha-alkenyl sulfonate is 1: (2-10).
As a preferable embodiment of this embodiment, the filler in the auxiliary material is composed of one or two of anhydrous sodium silicate, magnesium sulfate, magnesium carbonate, sodium sulfate and magnesium oxide; the coloring agent in the auxiliary material is one of carmine, brilliant blue, sunset red and lemon yellow; the essence in the auxiliary materials is one of lemon essence, sweet orange essence and flower fragrance essence; the film coating agent is any one of polyvinylpyrrolidone, PEG and beta-cyclodextrin.
The invention utilizes the strong oxidizing property (potential value of 1.85 v) of potassium monopersulfate composite salt to prepare the disinfectant capable of oxidizing chloride ions into hypochlorous acid. The potassium monopersulfate compound salt can form a chain reaction with chloride ions to continuously generate hypochlorous acid, has good disinfection effect, small irritation and no toxic or side effect, and is one of green, safe and efficient disinfectants.
The adjuvant is added with the thiazone, and the disinfectant can exert the effect by utilizing the high-efficiency permeation function of the thiazone.
The embodiment also provides a production process of the potassium monopersulfate microencapsulated compound disinfectant, which specifically comprises the following steps:
s1: mixing the auxiliary materials, namely mixing the auxiliary materials according to a certain proportion to obtain a mixture A1;
s2: crushing auxiliary materials, namely feeding the mixture A1 prepared in the step S1 into a crusher to be crushed to enable the mesh number to reach more than 200 meshes, so as to obtain crushed auxiliary materials A2;
s3: crushing the main material, namely taking a certain amount of potassium monopersulfate composite salt according to a proportion, and crushing the potassium monopersulfate composite salt at a specific temperature to ensure that the mesh number reaches more than 200 meshes to obtain a crushed main material B1;
s4: coating, coating and drying, namely feeding the crushed auxiliary material A2 prepared in the step S2 into a vacuum boiling drying granulation device, adding atomized coating agent into the device, and coating, coating and drying the crushed auxiliary material A2 to obtain a dried auxiliary material A3, wherein the moisture content of the dried auxiliary material A3 is less than 0.5%;
s5, conveying the crushed auxiliary material B1 prepared in the step S3 into a vacuum boiling drying granulating device, adding an atomized film coating agent into the device, and performing film coating treatment on the potassium monopersulfate composite salt to dry the auxiliary material B2, wherein the moisture content of the dried auxiliary material B2 is less than 0.5%;
s6: mixing and packaging, adding the prepared adjuvant A3 and the prepared main material B3 into a stirrer in proportion, mixing completely, making into final product, and packaging.
Wherein the temperature in step S3 is 20-60 deg.C, preferably, the temperature in step S3 is 40-50 deg.C.
Specifically, the temperature in step S3 in this embodiment is 40 ℃.
According to the invention, after the potassium monopersulfate composite salt and the auxiliary materials are treated by a microencapsulation process, the microencapsulated potassium monopersulfate composite salt is obtained, and the microencapsulated potassium monopersulfate composite salt is characterized in that the thiaketone is added in the process of microencapsulating the potassium monopersulfate composite salt, so that the microencapsulated potassium monopersulfate composite salt has high permeability and penetration effect, and active ingredients are promoted to enter the body through an epidermal layer. The potassium monopersulfate compound salt disinfectant prepared by microencapsulation treatment has the following advantages: the microencapsulation treatment increases the stability of the potassium monopersulfate composite salt, reduces the sensitivity of the potassium monopersulfate composite salt to humidity, and ensures that the product is not easy to agglomerate, absorb moisture and expand bags.
According to a disinfection effect formula: the disinfectant effect = C (concentration) · T (time), and the concentration of the disinfectant should be maintained so that the disinfectant has a certain disinfectant effect within a certain time. The invention adopts the microencapsulation treatment process and atomized thiazone, so that the potassium monopersulfate composite salt can still continuously maintain a certain disinfection concentration after meeting water, the long-acting property (15-30 days) of the potassium monopersulfate composite salt disinfection is obviously improved, the continuous effectiveness and the rapidity of the potassium monopersulfate composite salt are increased, the frequent input times of the disinfectant are reduced, and the susceptible animals are effectively protected.
The microencapsulated single-transition sulfur potassium hydrogen composite salt disinfection powder prepared by the formula and the microencapsulation process of the invention plays a role in slow release and prolongs the shelf life through microencapsulation treatment, and the observation under an electron microscope is shown in figure 2: the granules are relatively uniform, the specific gravity is relatively close, the mixed powder is relatively uniform, the color is bright, full and consistent, and the taste is excellent.
The table shows the comparison of the disinfection effect of the product prepared by the formula and the method of the embodiment 1 of the invention on the bacillus subtilis var niger killing effect with the traditional conventional disinfectant:
| killing logarithm value | Time of sterilization | Concentration of use | |
| Potassium monopersulfate microencapsulated compound disinfectant | ≥5 | 20min | 500ppm |
| Conventional potassium monopersulfate disinfectants | ≥5 | 60min | 1000ppm |
It is shown that the disinfectant has the same effect of killing black variety spore of Bacillus subtilis, and the disinfectant has fast killing speed and low use concentration as common potassium monopersulfate disinfectant.
Table two: control for increase in bacterial colony count (cfu) after sterilization
| The use concentration is 500ppm | 12h | 24h | 36h | 48h | 60h | 72h |
| Potassium monopersulfate microencapsulated compound disinfectant | 0 | 0 | 1.67×102 | 2.21×103 | 4.72×104 | 5.67×108 |
| Conventional potassium monopersulfate disinfectants | 0 | 1.75×102 | 2.63×104 | 3.91×108 | 5.37×1015 | 6.68×1016 |
Table two: the invention shows that the invention has longer lasting period than the conventional potassium monopersulfate disinfectant.
Example 2
The embodiment 2 is basically the same as the embodiment 1 in technical scheme, and the difference is that: 20 parts of potassium monopersulfate composite salt, 40 parts of bromine-containing compound, 15 parts of stabilizer, 5 parts of osmotic diffusion agent, 30 parts of filler, 0.4 part of colorant, 1 part of essence and 0.5 part of film coating agent in example 2.
Example 3
The embodiment 3 is basically the same as the embodiment 1, and the difference is that: in example 3, the potassium monopersulfate complex salt is 10 parts, the bromine-containing compound is 1 part, the stabilizer is 10 parts, the osmotic diffusion agent is 1 part, the filler is 5 parts, the colorant is 0.1 part, the essence is 0.2 part, and the coating agent is 0.5 part.
Example 4
The embodiment 4 is basically the same as the embodiment 1, and the difference is that: 60 parts of potassium monopersulfate composite salt, 70 parts of bromine-containing compound, 30 parts of stabilizer, 5 parts of osmotic diffusion agent, 30 parts of filler, 0.5 part of colorant, 1 part of essence and 3 parts of film coating agent in example 4.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that changes may be made in the embodiments and/or equivalents thereof without departing from the spirit and scope of the invention. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. Potassium monopersulfate microencapsulated compound disinfectant is characterized in that: the composition comprises a main material and an auxiliary material, wherein the main material is potassium monopersulfate composite salt, and the auxiliary material mainly comprises a bromine-containing compound, a stabilizer, a penetration diffusion agent, a filler, a colorant, essence and a coating agent.
2. The potassium monopersulfate complex disinfectant as set forth in claim 1, which is characterized in that: the potassium monopersulfate composite salt is composed of potassium monopersulfate, potassium bisulfate and potassium sulfate, and the molar ratio of the potassium monopersulfate to the potassium bisulfate to the potassium sulfate is 2: 1: 1.
3. the potassium monopersulfate microencapsulated complex disinfectant as claimed in claim 2, characterized in that: the bromine-containing compound in the auxiliary material consists of a substance A and a substance B, wherein the substance A is dibromohydantoin, the substance B is one of potassium bromide, sodium bromide and lithium bromide, and the weight part ratio of the substance A to the substance B is (0-1) to (1-5).
4. The potassium monopersulfate microencapsulated complex disinfectant as claimed in claim 3, characterized in that: the stabilizer in the auxiliary material consists of a substance C, a substance D and a substance E, wherein the substance C is hydroxyethylidene diphosphate or amino trimethylene phosphate, the substance D is sodium pyrophosphate or sodium hexametaphosphate, and the substance E is sulfamic acid or citric acid; the weight ratio of the substance C to the substance D to the substance E is 1: (2-5): (2-5).
5. The potassium monopersulfate microencapsulated complex disinfectant as claimed in claim 4, characterized in that: the osmotic diffusion agent in the auxiliary material comprises the thiazone and the alpha-sodium alkenyl sulfonate, wherein the weight ratio of the thiazone to the alpha-sodium alkenyl sulfonate is 1: (2-10).
6. The potassium monopersulfate microencapsulated complex disinfectant as claimed in claim 5, characterized in that: the filler in the auxiliary materials consists of one or two of anhydrous sodium silicate, magnesium sulfate, magnesium carbonate, sodium sulfate and magnesium oxide; the coloring agent in the auxiliary material is one of carmine, brilliant blue, sunset red and lemon yellow; the essence in the auxiliary materials is one of lemon essence, sweet orange essence and flower fragrance essence; the film coating agent is any one of polyvinylpyrrolidone, PEG and beta-cyclodextrin.
7. The potassium monopersulfate microencapsulated complex disinfectant as claimed in any one of claims 1 to 6, which is characterized in that: 10-60 parts of potassium monopersulfate composite salt, 1-70 parts of bromine-containing compound, 10-30 parts of stabilizer, 1-5 parts of osmotic diffusion agent, 5-30 parts of filler, 0.1-0.5 part of colorant, 0.2-1 part of essence and 0.5-3 parts of film coating agent.
8. The production process of the potassium monopersulfate microencapsulated compound disinfectant is characterized by comprising the following steps of: the method comprises the following steps:
s1: mixing the auxiliary materials, namely mixing the auxiliary materials according to a certain proportion to obtain a mixture A1;
s2: crushing auxiliary materials, namely feeding the mixture A1 prepared in the step S1 into a crusher to be crushed to enable the mesh number to reach more than 200 meshes, so as to obtain crushed auxiliary materials A2;
s3: crushing the main material, namely taking a certain amount of potassium monopersulfate composite salt according to a proportion, and crushing the potassium monopersulfate composite salt at a specific temperature to ensure that the mesh number reaches more than 200 meshes to obtain a crushed main material B1;
s4: coating, coating and drying, namely feeding the crushed auxiliary material A2 prepared in the step S2 into a vacuum boiling drying granulation device, adding atomized coating agent into the device, and coating, coating and drying the crushed auxiliary material A2 to obtain a dried auxiliary material A3, wherein the moisture content of the dried auxiliary material A3 is less than 0.5%;
s5, conveying the crushed auxiliary material B1 prepared in the step S3 into a vacuum boiling drying granulating device, adding an atomized film coating agent into the device, and performing film coating treatment on the potassium monopersulfate composite salt to dry the auxiliary material B2, wherein the moisture content of the dried auxiliary material B2 is less than 0.5%;
s6: mixing and packaging, adding the prepared adjuvant A3 and the prepared main material B3 into a stirrer in proportion, mixing completely, making into final product, and packaging.
9. The production process of the potassium monopersulfate microencapsulated compound disinfectant as claimed in claim 8, which is characterized in that: the temperature in the step S3 is 20 to 60 ℃.
10. The production process of the potassium monopersulfate microencapsulated compound disinfectant as claimed in claim 8, which is characterized in that: the temperature in the step S3 is 40-50 ℃.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111307262.9A CN113994973A (en) | 2021-11-05 | 2021-11-05 | Potassium monopersulfate microencapsulated compound disinfectant and production process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111307262.9A CN113994973A (en) | 2021-11-05 | 2021-11-05 | Potassium monopersulfate microencapsulated compound disinfectant and production process thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113994973A true CN113994973A (en) | 2022-02-01 |
Family
ID=79927696
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111307262.9A Pending CN113994973A (en) | 2021-11-05 | 2021-11-05 | Potassium monopersulfate microencapsulated compound disinfectant and production process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113994973A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116267919A (en) * | 2023-03-26 | 2023-06-23 | 广州叁个圆消毒技术有限公司 | Potassium hydrogen persulfate compound powder and preparation method thereof |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060078584A1 (en) * | 2004-10-13 | 2006-04-13 | Lightcap Edward B | Multi-functional oxidizing composition |
| CN101836659A (en) * | 2010-04-12 | 2010-09-22 | 湖南圣雅凯生物科技有限公司 | Compound potassium hydrogen persulfate disinfectant |
| CN108041073A (en) * | 2018-01-23 | 2018-05-18 | 广东贝特涞生物科技有限公司 | Potassium peroxymonosulfate disinfectant |
| CN108041072A (en) * | 2017-11-22 | 2018-05-18 | 湖北首祥生物科技有限公司 | A kind of hydrogen persulfate k particle and preparation method thereof |
| CN112741110A (en) * | 2021-02-23 | 2021-05-04 | 湖南广安动物保健品有限公司 | Green disinfectant capable of disinfecting by belt |
| CN113040168A (en) * | 2021-01-26 | 2021-06-29 | 广州迈高化学有限公司 | Efficient and safe oxone composite disinfectant and preparation method thereof |
| CN113207906A (en) * | 2021-05-02 | 2021-08-06 | 长沙创西生物科技有限公司 | Slow-release long-acting oxone disinfectant and preparation method thereof |
| CN113439758A (en) * | 2021-06-29 | 2021-09-28 | 上海泰缘生物科技股份有限公司 | Formula and use scheme of potassium monopersulfate low-temperature disinfectant |
-
2021
- 2021-11-05 CN CN202111307262.9A patent/CN113994973A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060078584A1 (en) * | 2004-10-13 | 2006-04-13 | Lightcap Edward B | Multi-functional oxidizing composition |
| CN101836659A (en) * | 2010-04-12 | 2010-09-22 | 湖南圣雅凯生物科技有限公司 | Compound potassium hydrogen persulfate disinfectant |
| CN108041072A (en) * | 2017-11-22 | 2018-05-18 | 湖北首祥生物科技有限公司 | A kind of hydrogen persulfate k particle and preparation method thereof |
| CN108041073A (en) * | 2018-01-23 | 2018-05-18 | 广东贝特涞生物科技有限公司 | Potassium peroxymonosulfate disinfectant |
| CN113040168A (en) * | 2021-01-26 | 2021-06-29 | 广州迈高化学有限公司 | Efficient and safe oxone composite disinfectant and preparation method thereof |
| CN112741110A (en) * | 2021-02-23 | 2021-05-04 | 湖南广安动物保健品有限公司 | Green disinfectant capable of disinfecting by belt |
| CN113207906A (en) * | 2021-05-02 | 2021-08-06 | 长沙创西生物科技有限公司 | Slow-release long-acting oxone disinfectant and preparation method thereof |
| CN113439758A (en) * | 2021-06-29 | 2021-09-28 | 上海泰缘生物科技股份有限公司 | Formula and use scheme of potassium monopersulfate low-temperature disinfectant |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116267919A (en) * | 2023-03-26 | 2023-06-23 | 广州叁个圆消毒技术有限公司 | Potassium hydrogen persulfate compound powder and preparation method thereof |
| CN116267919B (en) * | 2023-03-26 | 2023-09-12 | 广州叁个圆消毒技术有限公司 | Potassium hydrogen persulfate compound powder and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101233851B (en) | Disinfection effervescence tablet capable of continuously generating high oxidation-reduction potential | |
| CN111466406A (en) | Contact type binary chlorine dioxide slow-release gel and preparation method thereof | |
| CN101810874A (en) | Sustained-release chlorine dioxide gel, preparation method and application thereof | |
| CN107018990A (en) | A kind of disinfectant of decomposable asymmetric choice net formaldehyde | |
| JPH11228316A (en) | Preparation for sterilization and disinfection | |
| CN106726655A (en) | A kind of nanoscale fulvic acid peat facial mask and preparation method thereof | |
| CN100443124C (en) | Wet towel disinfected by chlorine dioxide and its preparing process | |
| CN113994973A (en) | Potassium monopersulfate microencapsulated compound disinfectant and production process thereof | |
| CN107537296A (en) | One kind is except formaldehyde composition, its preparation method and purification air kit | |
| KR102115133B1 (en) | Hand sanitizer composition for preventing infectious diseases | |
| CN111972435A (en) | Preparation method of nano-silver-graphene oxide composite material | |
| CN102697804A (en) | Solid molecular iodine disinfectant and preparation method thereof | |
| KR101246849B1 (en) | Minerals aqueous solution and its manufacturing method | |
| CN104256849B (en) | A kind of kill mould bacteria composition and its application | |
| CN101496530B (en) | Composite disinfecting effervescent tablet and preparation method thereof | |
| CN102396465A (en) | Trichloroiminocyanuric acid effervescent tablet and preparation method thereof | |
| CN1556046A (en) | Synergism type chlorine dioxide bactericide and its manufacturing method and use in aquatic culture | |
| CN112120020A (en) | Chlorine dioxide slow-release particle sterilizing disinfectant and preparation method thereof | |
| CN113142250A (en) | Air sterilization and disinfection composition | |
| CN103719647B (en) | A kind of compound prescription fruits and vegetables agricultural chemicals falls residual dose | |
| US9427411B2 (en) | Oxygenated antimicrobial topical composition | |
| CN101595891B (en) | Chlorine dioxide composition with selective antioxidation | |
| CN111603425A (en) | Multifunctional effervescent tablet of skin disinfection cleaning solution and preparation method thereof | |
| CN103238595A (en) | Special concentrated type glutaraldehyde disinfectant for endoscopes and preparation method of special concentrated type glutaraldehyde disinfectant | |
| CN117530291A (en) | Activation-free slow-release air disinfectant and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220201 |
|
| RJ01 | Rejection of invention patent application after publication |