KR102115133B1 - Hand sanitizer composition for preventing infectious diseases - Google Patents

Abstract

The present invention relates to a hand sanitizer composition for preventing infectious diseases, which contains 38 to 39 parts by weight of first PLA-coating type slightly-acidic hypochlorous acid water with respect to 100 parts by weight of ethanol. Accordingly, the hand sanitizer composition is provided in a spray or gel type in the user′s hand, and can provide an effect in which a user can sequentially receive a PLA capsule-type sterilizer and components harmful to the human body by rubbing hands.

Description

Hand sanitizer composition for preventing infectious diseases}

The present invention relates to a hand sanitizer composition for preventing an infectious disease, and more specifically, it is provided in a spray type or a gel type in the user's hand, and the user may sequentially receive the PLA capsule type sterilizer and components harmful to the human body by rubbing the hand. It relates to a hand sanitizer composition for preventing infectious diseases to enable.

Mask and hand sanitizer for personal hygiene following the 2020 pandemic of coronavirus infection-19 (COVID-19), a respiratory infection caused by a new type of coronavirus that first spread in the world in Wuhan, China in December 2019. The importance of products for personal hygiene, such as, is growing.

Hand sanitizer, also known as hand sanitizer or hand sanitizer, is a broad concept that includes a substitute for hand washing with water, as well as a substitute for hand washing with water. B. Gel-type disinfectants are predominant.

However, although the main components of these hand sanitizers are mainly composed of ethanol, the limitations of the ethanol content in the hand sanitizers can be vulnerable to the above-mentioned new infectious diseases due to the limited sterilization power. This is required.

Republic of Korea Patent Application No. 10-2008-0057530 (2008.06.18) "Disinfectant composition for hand including mastic" Republic of Korea Patent Application No. 10-2010-0008480 (2010.01.29) "A hand sanitizer comprising a hemp extract and the method for preparing them"

The present invention is to solve the above problems, and is provided in a spray type or a gel type in the user's hand, and an infectious disease for allowing the user to sequentially receive the PLA capsule type sterilizer and components harmful to the human body in sequence It is to provide a hand sanitizer composition for prevention.

In addition, the present invention is to provide a hand disinfectant composition for preventing infectious diseases to provide a beneficial effect on the human body through a Moringa extract, as well as safely providing a mildly acidic hypochlorous acid water with strong sterilizing power with ethanol. .

However, the objects of the present invention are not limited to the above-mentioned objects, and other objects not mentioned will be clearly understood by those skilled in the art from the following description.

In order to achieve the above object, the hand disinfectant composition for preventing infectious diseases according to an embodiment of the present invention may be characterized in that it comprises 38 to 39 parts by weight of the first PLA-coated micro-acidic hypochlorous acid water with respect to 100 parts by weight of ethanol. .

In this case, when used as a spray-type hand sanitizer, 95 to 99 parts by weight of deep ocean water is additionally mixed with respect to 100 parts by weight of ethanol, or when it is used as a gel-type hand sanitizer, 75 to 87 parts by weight of water-soluble cellulose is additionally mixed. can do.

The hand disinfectant composition for preventing infectious diseases according to an embodiment of the present invention is provided in a spray type or a gel type in the user's hand, and the user can rub the hand to sequentially receive the PLA capsule type sterilizer and components harmful to the human body in order. Can provide.

In addition, the hand disinfectant composition for preventing infectious diseases according to another embodiment of the present invention is an eco-friendly material, which provides safe disinfecting acidic hypochlorous acid water with ethanol as well as a beneficial effect on the human body through Moringa extract There is an effect to do.

1 to 3 is a graph showing the experimental results for the first PLA-based coating agent in the first PLA-coated acidic hypochlorous acid water in the hand disinfectant composition for preventing infectious diseases according to an embodiment of the present invention.

Hereinafter, a detailed description of a preferred embodiment of the present invention will be described with reference to the accompanying drawings. In the following description of the present invention, when it is determined that a detailed description of related known functions or configurations may unnecessarily obscure the subject matter of the present invention, the detailed description will be omitted.

The hand disinfectant composition for preventing infectious diseases according to the embodiment of the present invention comprises 1 to 2 parts by weight of 1 PLA to 2 parts by weight of 38 to 39 parts by weight of acidic hypochlorous acid, 24.7 parts by weight of Moringa extract from PLA It contains 0.7 to 0.8 parts by weight of surfactant and 0.3 to 0.6 parts by weight of nonionic surfactant, and when used as a spray-type hand sanitizer, additionally mix 95 to 99 parts by weight of deep ocean water with 100 parts by weight of ethanol or use it as a gel-type hand sanitizer. In case, it may be prepared by further mixing 75 to 87 parts by weight of water-soluble cellulose.

Here, deep ocean water has a low temperature stability of about 5 ℃ or less, so it has excellent low-temperature stability, and photovoltaic properties do not occur because sunlight does not reach compared to surface water, so inorganic nutrients such as nitrogen, phosphorus, and silicic acid are needed for plant growth. It contains a lot of salts, and contains essential trace elements and various minerals in balance. Looking into the effectiveness of deep ocean water, zinc (Zn), selenium (Se), and manganese (Mn), in addition to magnesium (Mg), calcium (Ca), potassium (K), and sodium (Na), are the four essential minerals. It contains minerals that are richer and more balanced than surface water or groundwater that we use as drinking water. That is, deep ocean water contains many mineral components, and among them, the main component of deep ocean water is magnesium, and magnesium is one of the important nutrients for the human body, and is a component in the cell. In addition, it may be provided as a catalytic material essential for cell activity.

Here, the concentration of ethanol used in the present invention may be 90 to 100% (v / v), more preferably 85% (v / v). Ethanol may be an edible grain fermentation spirit. Ethanol not only has a protein coagulation effect and a cell lipid layer removal effect, but can be consumed as an ingredient in alcohol, and even if ingested, it is harmless to the human body because it is finally oxidized to carbon dioxide through acetaldehyde in the body. Since it contains ethanol, which is harmless to the human body, it is easy to distribute and store and has no toxicity, so it has excellent biosafety properties.

Ethanol may cause excessive irritation or unpleasant odor to the skin when excessively contained in the composition despite excellent sterilization effect, whereas usability may be reduced, whereas when contained in a small amount, the sterilization effect may not be sufficiently achieved. The hand disinfectant composition for preventing infectious diseases is additionally added with the acidic hypochlorous acid water as an auxiliary bactericide to increase the sterilization effect, but by adding 28 to 29 parts by weight of the first PLA coating type of the minor acidic hypochlorous acid water to 100 parts by weight of ethanol, The amount of ethanol can be significantly reduced compared to the ethanol content.

The acidic hypochlorous acid water used in the present invention has a pH of 5.0 to 6.5 and an effective chlorine concentration of 20 to 30 ppm, and is harmless to the human body to the extent that it can be used for sterilization of food ingredients and food.

The acidic hypochlorous acid water can be obtained by electrolysis of 3 to 7% of dilute hydrochloric acid for food additives, sun salt, and tap water in a diaphragm electrolyzer.

Micro-acidic hypochlorous acid water is added to compensate for the disadvantages of low sterilization power as a side effect of lowering the content of ethanol, thereby sterilizing and disinfecting areas that can sterilize and disinfect food poisoning fungi, yeast, viruses, apobacteria, and various pathogenic microorganisms. You have.

Here, the acidic hypochlorous acid used in the present invention is slightly acidic with a pH of 5.0 to 6.5, but when the pH is less than 5, the molecularly effective chlorine hypochlorous acid, which is a molecularly effective chlorine component, volatilizes with chlorine, and thus the effectiveness of the acidic hypochlorous acid water. There are problems such as lowering the chlorine concentration, deteriorating storage safety, and causing irritating chlorine and metal corrosion. When the pH exceeds 6.5, the production of hypochlorous acid ions increases and the sterilizing power is weakened.

In addition, the acidic hypochlorous acid water according to the present invention should have an effective chlorine concentration of 20 to 30 ppm, and when the effective chlorine concentration is less than 20 ppm, effective sterilization and disinfection effects cannot be expected despite the ethanol content, and the effective chlorine concentration is 30 ppm. If the amount exceeds, there is a problem in that, in addition to the ethanol content, the sterilizing power is unnecessarily large and the economic efficiency is significantly reduced.

The acidic hypochlorous acid used as a liquid composition used in the present invention is in a very unstable state, and when exposed to direct sunlight or air or infected with a virus, there is a problem that it is reduced to water that is stabilized while a reverse reaction occurs.

Therefore, in the present invention, in the process of preparing a hand disinfectant composition for preventing infectious diseases, which adds acidic hypochlorous acid, the first PLA-coated type of acidic hypochlorous acid is used to prevent the acidic hypochlorous acid from being exposed to direct sunlight, air, or viruses. It is desirable to prepare a hand sanitizer composition for preventing infectious diseases.

PLA used in the first PLA-based coating agent of the first PLA-coated type of acidic hypochlorous acid used in the present invention is a natural plant-based raw material based on corn starch, and does not contain synthetic resin (PC, ABS, etc.). Decomposes 100% under conditions. In addition, it is possible to prevent the generation of harmful substances such as dioxin and other environmental pollution. PLA (PolyLactic Acid) can be substituted for injection and extruded plastics, and it can be commercialized as an innovative eco-friendly resin with general-purpose physical properties. On the other hand, PLA has properties for crystallinity, natural circulation, biocompatibility, CO ₂ reduction, etc. PLA is a plant-based raw material and is an eco-friendly material capable of natural decomposition of products.

Cellulose nanofibers may be added to the PLA resin for producing the PLA-based coating agent used for the first acidic hypochlorous acid of the first PLA coating type in the present invention, and the weight ratio of the PLA resin and the cellulose nanofibers is 4.2 to 5.5: 1 The mixture is made to be made of a capsule type, and then, a micro-acidic hypochlorous acid water of the PLA coating type is produced in the form of injecting a micro-acidic hypochlorous acid into the inside, so that a hand sanitizer composition for preventing an infectious disease is sprayed in a form such as spraying. If the user rubs the hand sanitizer composition for preventing infectious diseases with the user's hand rubbed in the hand of the user outside the container containing the hand sanitizer composition for preventing the epidemic without being exposed to direct sunlight, air, or infected with viruses, etc. As the PLA-based coating agent of the PLA-based type of acidic hypochlorous acid is torn, the acidic hypochlorous acid water flows to the outside of the PLA-based coating agent to increase the sterilizing effect with alcohol as the main component in the user's hand.

Example 1 (P1) of the first PLA-based coating agent to which these cellulose nanofibers are added is compared to the coating agent (B) prepared using only PLA resin, as shown in FIGS. 1 to 3, tensile strength and fracture strength, and rupture. It was found that the strength was all improved.

 At this time, the tensile strength is based on TAPPI T 404 om-87, and Hounsfield's tensile strength meter is used, and the rupture strength is based on TAPPI T 511 om-83. When measuring the internal strength, the tensile load was 0.4 kg, the stiffness was Clark type according to TAPPI T 451 cm-84, and the bursting strength was Mullen low pressure tester according to TAPPI T 403 om-85.

In addition, the first PLA-based coating agent to which cellulose nanofibers are added has a high specific surface area, specific strength and low density of cellulose nanofibers, and thus not only exhibits excellent physical properties corresponding to the reinforcing function of PLA resins, but also requires only a very small amount. A composite excellent in thermal and mechanical properties can be obtained, and environmentally friendly and lightweight properties can be provided.

That is, the first PLA-based coating agent is manufactured in a microcapsule form, and may contain and contain micro-acidic hypochlorous acid therein, and the first PLA-based coating agent used for the first-acidic hypochlorous acid type of the PLA coating type The PLA coating type can achieve 34 to 35 parts by weight based on 100 parts by weight of the acidic hypochlorous acid, wherein if it is less than 34 parts by weight, the internal acidic hypochlorous acid water has a critical time (30 seconds to 45) at room temperature (25 ° C). Second) occurs automatically, and when it exceeds 35 parts by weight, the viscosity of the particles (capsules) increases, turbidity or sediment appears, and the hand sanitizer composition for preventing infectious diseases, including deep ocean water, is manufactured as a spray type. If possible, the problem that the spraying becomes impossible occurs.

The Moringa extract contained in the 2nd PLA coating type Moringa extract uses the seeds and roots of Moringa and can be used to kill bacteria and fungi and purify water.

The Moringa extract that enters the 2nd PLA coating type Moringa extract is added with 5 to 6 multiples (w / w) of distilled water per 100 g of crushed Moringa seeds and roots, followed by extraction of hot water at 75 to 85 ° C for 2 hours. do. After filtering this (Whatman No.2 filter paper), add 20 to 30 parts by weight to 100 parts by weight to the moringa extracted with proneronase enzyme before concentration, and then freeze-dried the concentrated Moringa extract to collect moisture. Obtained by complete removal.

The moringa on the Moringa extract produced in the present invention includes Proxeronine, which is activated as Xeronine by an enzyme called proneronase, which may be involved in the cell regeneration process.

In other words, xeronine activates more than 1500 enzymes in the human body, combines vitamins, minerals, antioxidants, and serotonin in the body to regenerate damaged cells to normal cells, restore cellular function, and oxygen and nutrients into the blood. It is a catalytic activity that is essential for the transporting cell activity.

On the other hand, the second PLA-based coating agent used in the Moringa extract of the 2 PLA coating type is the same as the first PLA-based coating agent, but the cellulose nanofiber is added to the PLA resin for producing the second PLA-based coating agent in the additional content. , PLA resin and cellulose nanofibers in a weight ratio of 3.3 to 4.3: 1.8 to 1.9, but a honeycomb structured grid of cellulose nanofibers is made of a capsule filled with PLA resin, and then produced in a capsule type. The Moringa extract of the 2nd PLA coating type is produced in the form of injecting the Moringa extract mixed with, and the hand sanitizer composition for preventing infectious diseases is buried in the hand of the user outside the container containing the hand sanitizing agent composition for preventing infectious diseases in the form of spraying, etc. When the user rubs the hand sanitizer composition for preventing an infectious disease by hand in a state, the first PLA-based coating agent of the first PLA-coated aqueous acidic hypochlorous acid inside the plague-resistant hand sanitizer composition is torn and pushed out of the first PLA-based coating agent. The acidic hypochlorous acid water flows, and the second PLA-coated moringa extract is added to the outside of the 2nd PLA-based coating agent due to the honeycomb structure and content difference of cellulose nanofibers in the state of increasing the sterilization effect with alcohol as the main component in the user's hand. The 2 PLA-based coating agent is decomposed between 2 and 5 minutes by 4.7 to 6.8 parts by weight of an ionic surfactant and 2.5 to 4.5 parts by weight of a nonionic surfactant in a non-flowing state, and the Moringa extract mixed with proneronase is By flowing into the user's hand, the user can be provided with the above-described effects of xeronine.

The anionic surfactant is contained in an amount of 0.7 to 0.8 parts by weight based on 100 parts by weight of ethanol to provide decomposition and cleaning power for the capsules of the first PLA-coated type acidic hypochlorous acid water and the second PLA-coated type Moringa extract. Preferably, while having sufficient cleaning power, it is contained in an amount free to spray in the spray-type hand sanitizer composition for preventing an infectious disease, and if it is less than 0.7 parts by weight, the cleaning power and the decomposition power are insignificant. Impossibility and foaming may occur.

On the other hand, anionic surfactants are alkyl sulfates and alkyl ether sulfates, and in particular, sodium alkyl sulfates containing about 10 to 22 carbon atoms, triethanolamine alkyl sulfates, ammonium alkyl sulfates, ammonium alkyl ether sulfates containing ethoxy groups and sodium alkyls And derivatives such as ether sulfate.

Among these anionic surfactants, those derived from lauryl alcohol and straight chain alcohols derived from palm oil are preferable. Particularly preferably, lauryl sulfate triethanol amine, polyoxyethylene sodium lauryl sulfate, sodium lauryl sulfate, sodium lauryl sulfate, and polyoxy produced by neutralizing the resulting mixture having an average of 3 moles of alcohol molar allowance ethylene oxide with an average of 3 moles One type selected from ethylene lauryl ammonium sulfate or the like is used or a mixture of two or more types is used.

More preferably, triethanolamine laury sulfate, which is inexpensive, is used.

The nonionic surfactant is intended to have a solubilization effect for the capsules of the co-cleaning and the first PLA-coated type acidic hypochlorous acid water and the second PLA-coated type Moringa extract and to adjust the pH, 100 parts by weight of ethanol of the present invention With respect to non-ionic surfactant, 0.3 to 0.6 parts by weight may be included. At this time, if it is less than 0.3 parts by weight, the solubilizing effect of the auxiliary cleaning and especially the 2 PLA coating type Moringa extract is insignificant, and when it exceeds 0.6 parts by weight, viscosity increase and pH adjustment are not easy, so hand sanitizer for preventing spray type infectious disease In the composition, spraying becomes impossible freely and may be rather irritating to the skin and the effect of non-ionic function may be halved.

Nonionic surfactants include derivatives such as alkanol amides and alkyl oxide amines. Preferably, one selected from derivatives such as lauric acid diethanol amide, lauryl diethyl amine oxide, palm oil alkyldimethylamine oxide, palm oil fatty acid diethanol amide, and palm oil fatty acid monoethanol amide is used alone, or two or more thereof Mix and use. More preferably, an inexpensive cocoamide diethanol amine (Cocoamide DEA) is used.

As described above, in the present specification and drawings, preferred embodiments of the present invention have been disclosed, and although specific terms are used, they are merely used in a general sense to easily describe the technical contents of the present invention and to help understand the invention. , It is not intended to limit the scope of the present invention. It is obvious to those skilled in the art to which the present invention pertains that other modified examples based on the technical idea of the present invention can be implemented in addition to the embodiments disclosed herein.

Claims (2)

With respect to 100 parts by weight of ethanol, 38 to 39 parts by weight of the first PLA-coated acidic hypochlorous acid, 24.7 parts by weight of the second PLA-coated moringa extract, 0.7 to 0.8 parts by weight of anionic surfactant, 0.3 of nonionic surfactant It contains 0.6 to 0.6 parts by weight, and when used as a spray-type hand sanitizer, 95 to 99 parts by weight of deep ocean water is additionally mixed with respect to 100 parts by weight of ethanol, or 75 to 87 parts by weight of water-soluble cellulose when used as a gel-type hand sanitizer. And
The concentration of ethanol is 85% (v / v), which is edible grain fermentation alcohol,
The 1st PLA coating type, the acidic hypochlorous acid used in the acidic hypochlorous acid water has a pH of 5.0 to 6.5 and an effective chlorine concentration of 20 to 30ppm, and 3 to 7% of dilute hydrochloric acid for food addition, sun salt and tap water. Obtained by electrolysis in a diaphragm electrolyzer,
Cellulose nanofibers are added to the PLA resin for producing a PLA-based coating agent used for the first PLA-coated acidic hypochlorous acid, and the weight ratio of the PLA resin and the cellulose nanofibers is 4.2 to 5.5: 1. After being produced in the form of a capsule, a mildly acidic hypochlorous acid of the PLA coating type is produced in the form of injecting a weakly acidic hypochlorous acid inside,
The first PLA-based coating agent is prepared in the form of microcapsules, and contains and contains micro-acidic hypochlorous acid therein, and is formed by forming 34 to 35 parts by weight based on 100 parts by weight of PLA-type minor acidic hypochlorous acid water,
The Moringa extract contained in the 2 PLA coating type Moringa extract uses the seeds and roots of Moringa, and after adding 5 to 6 multiples (w / w) of distilled water per 100 g of the crushed Moringa seeds and roots, , Hot water extracted at 75 to 85 ° C. for 2 hours, filtered with hot water extract (Whatman No.2 filter paper), and 20 to 30 parts by weight based on 100 parts by weight of the moringa extracted with proneronase enzyme before concentration After the addition, the concentrated Moringa extract is obtained by freeze-drying to completely remove moisture,
The 2 PLA-based coating agent used in the Moringa extract of the 2 PLA coating type is formed of the same component as the 1 PLA-based coating agent, but the cellulose nanofiber is added to the PLA resin for producing the 2 PLA-based coating agent, The weight ratio of PLA resin and cellulose nanofiber is 3.3 to 4.3: 1.8 to 1.9, but the grid of honeycomb structured cellulose nanofiber is filled with PLA resin, which is produced in capsule type. Moringa extract of the 2nd PLA coating type is produced in the form of injecting the Moringa extract mixed with Naze,
The anionic surfactant is contained to provide decomposition promoting and cleaning power for the capsules of the first PLA-coated type acidic hypochlorous acid water and the second PLA-coated type Moringa extract, lauryl sulfate triethanol amine, polyoxyethylene lauryl sodium sulfate , Sodium lauryl sulfate, ammonium lauryl sulfate, and polyoxyethylene lauryl ammonium sulfate, or the like, or a mixture of two or more,
The nonionic surfactant is intended to have a solubilization effect for the capsules of the co-cleaning and the first PLA-coated type acidic hypochlorous acid water and the second PLA-coated type Moringa extract, and to adjust the pH, lauric acid diethanol amide, For preventing infectious diseases, characterized in that one selected from lauryl diethyl amine oxide, palm oil alkyldimethylamine oxide, palm oil fatty acid diethanol amide, and palm oil fatty acid monoethanol amide is used alone or by mixing two or more. Hand sanitizer composition.
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