CN113952413A - 一种用于治疗皮肤病的大黄甘草洗液 - Google Patents
一种用于治疗皮肤病的大黄甘草洗液 Download PDFInfo
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Abstract
本发明公开了一种用于治疗皮肤病的大黄甘草洗液，每制备1000ml大黄甘草洗液所需的原料配比是：大黄10g、甘草20g、马齿苋12g、野菊花12g、艾叶10g、地骨皮10g、酒黄精12g、当归12g、制何首乌12g。制备工艺是：将上述九种原料加12倍重量的水煎煮二次，每次1.5小时，滤过，合并滤液，滤液浓缩至1000ml，静置过夜，滤过，加水至1000ml，混匀，分装，高压蒸汽灭菌45分钟，即得到大黄甘草洗液。本发明大黄甘草洗液用于治疗皮肤病“四弯风”，疗效显著，能明显消退、缓解局部红丘疹，肥厚，脱屑，少量渗出等皮肤表现，明显缓解皮肤瘙痒，改善患者生活质量。
Description
技术领域
本发明涉及中药技术领域，具体是一种用于治疗皮肤病的大黄甘草洗液。
背景技术
目前用于治疗皮肤病的外用药物有很多种，但疗效均不太理想，而且市面上没有专门针对皮肤病“四弯风”(即特应性皮炎)的药物，因此，急需一种专用于治疗皮肤病“四弯风”的外用药物。
发明内容
本发明所要解决的技术问题是提供一种用于治疗四弯风的大黄甘草洗液，该洗液易于制备，且疗效显著。
本发明以如下技术方案解决上述技术问题：
本发明一种用于治疗皮肤病的大黄甘草洗液，每制备1000ml洗液所需的原料配比是：大黄10g、甘草20g、马齿苋12g、野菊花12g、艾叶10g、地骨皮10g、酒黄精12g、当归12g、制何首乌12g；
制备工艺是：将上述九种原料加12倍重量的水煎煮二次，每次1.5小时，滤过，合并滤液，滤液浓缩至1000ml，静置过夜，滤过，加水至1000ml，混匀，分装，高压蒸汽灭菌45分钟，即得到大黄甘草洗液。
本发明用于治疗皮肤病的大黄甘草洗液具有以下优点：
1)本发明以纯中药为原料，具有使用方便、疗效确切、无明显副作用、治愈率高、复发率低等特点，用于治疗皮肤病“四弯风”(西医病名：特应性皮炎)疗效显著，能明显消退、缓解局部红丘疹，肥厚，脱屑，少量渗出等皮肤表现，明显缓解皮肤瘙痒，改善患者生活质量。
2)本发明配方中无贵重药材，中药来源充足，价廉物美，使用安全，易于推广。
具体实施方式
下面对本发明的技术方案作进一步的描述。
每制备1000ml本发明大黄甘草洗液，所需的原料配比是：大黄10g、甘草20g、马齿苋12g、野菊花12g、艾叶10g、地骨皮10g、酒黄精12g、当归12g、制何首乌12g。
本发明大黄甘草洗液的制备工艺是：将上述九种原料加12倍重量的水煎煮二次，每次1.5小时，滤过，合并滤液，滤液浓缩至1000ml，静置过夜，滤过，加水至1000ml，混匀，分装，高压蒸汽(80kPA,105℃)灭菌45分钟，即得到大黄甘草洗液。
本发明采用的原料均为市售中药原料，易于取得，成本低廉。
本发明大黄甘草洗液的用法用量是：外用，取本品100ml，成人加20至25倍重量的温水浸洗患处15～20分钟，一日两次；儿童加25～30倍重量的温水浸洗患处15～20分钟，一日两次。
本发明大黄甘草洗液的临床应用情况如下：
2016年-2020年，将本发明大黄甘草洗液应用于广西南宁市中医医院皮肤科门诊，在治疗皮肤病“四弯风”(即特应性皮炎)中收到良好效果，治愈率达97％以上。部分案例记录如下：
【案例1】
包某某，女，28岁。病史：15年前无明显诱因下全身散在红斑丘疹伴瘙痒，皮疹以肘窝和腘窝明显，1周前皮疹再次加重，泛发全身，双眼睑肿胀，瘙痒剧烈。刻诊：全身泛发红斑、丘疹，以颜面部、肘窝、腘窝处明显，伴有强烈瘙痒，胸闷纳呆，口苦，大便干，小便赤少，舌质红，苔薄黄，脉滑数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒症状较前缓解，皮损面积较前较少，后续治疗以本发明大黄甘草洗液进行外洗为主，1月后病情基本控制。
【案例2】
马某某，男，8岁。病史：3年前无明显诱因下额部、耳部出现红斑、丘疹，伴瘙痒，搔抓后渗液，未予重视皮疹逐渐增多至肘关节、大腿屈侧等，皮损反复发作，多于换季时复发。刻诊：全身皮肤干燥，面部、双耳后、肘、腘窝处片状红斑，上覆细小白色鳞屑，未见明显渗液，躯干、四肢可见色素沉着及色素减退斑，伴瘙痒以夜间明显，食欲不佳，腹胀乏力，大便溏。舌质淡红，苔薄白腻，脉滑。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒症状较前缓解，皮损以红斑、丘疹为主，无明显水疱、糜烂。后续治疗以本发明大黄甘草洗液进行外洗为主，20天后病情基本控制。
【案例3】
黄某某，女，2岁。病史：10天前无明显诱因下小腿腘窝处弥漫性红斑、丘疹，对称分布，伴强烈瘙痒，热水烫洗后瘙痒缓解，皮损加重。刻诊：双侧腘窝处局限性暗红色斑，弥漫丘疹、丘疱疹，些许糜烂、流滋，夜间瘙痒明显。心烦口渴、纳差，大便干硬，小便短赤，舌红，苔薄黄腻，脉弦数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：皮损以暗红色斑、丘疹为主，无明显水疱、糜烂。后续治疗以本发明大黄甘草洗液进行外洗为主，20天后病情基本控制。
【案例4】
谭某，18岁，男。刻诊：肘、腘窝部皮肤干燥肥厚、丘疹、鳞屑，少许色素沉着，腹胀纳差，寐不安，舌淡红，苔薄白，脉细数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，21天后病情基本控制。
【案例5】
张某某，女，4岁。病史：5月前无明显诱因下头面部红斑、丘疹、丘疱疹，剧烈瘙痒。刻诊：头面、耳廓处红斑、丘疹，附有黄白色鳞屑，腹胀纳差，寐不安，舌淡红，苔薄白，脉细数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，28天后病情基本控制。
【案例6】
幸某某，女，30岁。病史：3年前无明显诱因下出现全身散在红斑、丘疹、鳞屑，伴瘙痒，面部尤甚。曾在外院服西药治疗，症状无缓解，逐渐加重。刻诊：全身散在红斑、丘疹，表面附有白色鳞屑，面部尤甚，伴瘙痒，大便溏烂，小便正常，舌红苔黄腻，脉滑。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，45天后病情基本控制。
【案例7】
刘某某，女，8岁。病史：5年前无明显诱因下全身散在红斑、丘疹、丘疱疹、鳞屑，伴瘙痒，腘窝、肘窝处明显。刻诊：全身多处红斑、丘疹，部分呈苔藓化，表面附有白色鳞屑，肘窝、腘窝处明显，伴瘙痒，大便干，小便黄，舌红苔黄腻，脉滑数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，15天后病情基本控制。
【案例8】
王某某，12岁，男。病史：4月前无明显诱因下颜面部红斑、丘疹，剧烈瘙痒。刻诊：头面、耳廓处红斑、丘疹，附有黄白色鳞屑，腹胀纳差，寐不安，舌淡红，苔薄白，脉细数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗，使用7天后，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，15天后病情基本控制。
【案例9】
周某某，女，18岁。病史：2年前无明显诱因下出现全身散在红斑、丘疹、鳞屑，伴瘙痒，面部、肘腘窝处明显。刻诊：全身散在多处红斑、丘疹，少许鳞屑，以肘腘窝处明显，伴瘙痒，腹胀、大便溏，小便正常，舌红苔腻，脉滑细。后经使用本发明大黄甘草洗液进行湿敷外洗治疗7天，同时服用清热健脾汤7剂，分早晚温服，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，21天后病情基本控制。
【案例10】
覃某某，女，8岁。病史：4年前无明显诱因下肘腘窝红斑、丘疹、丘疱疹，伴瘙痒。刻诊：皮肤干燥，肘腘窝处红斑、丘疹，呈苔藓化，表面附有白色鳞屑，伴瘙痒，大便干，小便黄，舌红苔黄腻，脉滑数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗7天，同时服用消风导赤汤7剂，分早晚温服，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，15天后病情基本控制。
【案例11】
朱某某，男，5岁。刻诊：肘、腘窝部皮肤干燥肥厚、丘疹、鳞屑，少许色素沉着，腹胀纳差，寐不安，舌淡红，苔薄白，脉细数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗7天，同时服用滋阴除湿汤7剂，分早晚温服，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，21天后病情基本控制。
【案例12】
严某某，女，1岁。病史：10月前无明显诱因下头面部红斑、丘疹、丘疱疹，剧烈瘙痒。刻诊：头面部、耳廓处红斑、丘疹，附有黄白色鳞屑，腹胀纳差，舌淡红，苔薄白，脉细数。初步诊断：特应性皮炎(四弯风)。后经使用本发明大黄甘草洗液进行湿敷外洗治疗7天，同时服用健脾除湿汤7剂，分早晚温服，复诊情况：瘙痒缓解，皮损减轻。后续治疗以本发明大黄甘草洗液进行外洗为主，31天后病情基本控制。
Claims (1)
1.一种用于治疗皮肤病的大黄甘草洗液，其特征在于：每制备1000ml洗液所需的原料配比是：大黄10g、甘草20g、马齿苋12g、野菊花12g、艾叶10g、地骨皮10g、酒黄精12g、当归12g、制何首乌12g；
制备工艺是：将上述九种原料加12倍重量的水煎煮二次，每次1.5小时，滤过，合并滤液，滤液浓缩至1000ml，静置过夜，滤过，加水至1000ml，混匀，分装，高压蒸汽灭菌45分钟，即得到大黄甘草洗液。
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