CN102988890A - 治疗黄褐斑的纯中药制剂 - Google Patents
治疗黄褐斑的纯中药制剂 Download PDFInfo
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Abstract
一种治疗黄褐斑的纯中药制剂，其特征在于，选用的原料药材及重量组分分别是：黄芪15份、桃仁10份、红花6份、川芎6份、银柴胡8份、当归9份、炒白芍9份、地黄9份、香附9份、炒枳壳9份、郁金6份、炙甘草3份。本发明药物具有补血养血、活血消瘀、养阴生津、舒肝健脾、理气通血功效，用于经血不调、精神压力过重所致色斑；黄褐斑。
Description
治疗黄褐斑的纯中药制剂
技术领域
[0001] 本发明涉及一种用于治疗黄褐斑的纯中药制剂，属于中药领域。
背景技术
[0002] 黄褐斑俗称肝斑、妊娠斑。一般多发生在面部，故又称“面部色斑”。本病呈对称性淡褐色至深褐色斑，形状及大小不定，无自觉症状，边境明显。现代的生活节奏快，工作压力重，加之熬夜，好多都出现颜面斑、黑眼圈、面色灰暗等症状，这些面部问题既影响了她们工作上的上进和生活信心又更加重了心理上的负担。爱美之心人皆有之。为消除她们的这些面部问题，增加调节好她们容光焕发的上进的工作和生活信心，减消她们心理上的负担，临床上我通过当归补血汤、四物汤、血府逐瘀汤加减应用诸多患病者的亲身实验，精心研究观察，实践发明了本发明成方。 发明内容
[0003] 本发明的目的在于提供一种具有补血养血、活血消瘀、养阴生津、舒肝健脾、理气通血功效的中药制剂，用于治疗黄褐斑。
[0004] 本发明采用的技术方案：所述治疗黄褐斑的纯中药制剂，选用的原料药材及重量组分分别是：黄芪15份、桃仁10份、红花6份、川芎6份、银柴胡8份、当归9份、炒白芍9份、地黄9份、香附9份、炒积壳9份、郁金6份、炎甘草3份。
[0005] 本发明选取的原料中药材中，其功效和药理作用分别是：
[0006] 黄芪：中药材黄芪为豆科草本植物蒙古黄芪、膜荚黄芪的根，具有补气固表、利水退肿、托毒排脓、生肌等功效。黄芪的药用迄今已有2000多年的历史，现代研究，黄芪含皂甙、蔗糖、多糖、多种氨基酸、叶酸及硒、锌、铜等多种微量元素。有增强机体免疫功能、保肝、利尿、抗衰老、抗应激、降压和较广泛的抗菌作用。
[0007]桃仁：蔷薇科植物桃 Amygdalus persica L.或山桃 Amygdalus davidiana (Carr.)C. de Vos ex Henry的干燥成熟种子。【化学成分】含苦杏仁式（amygdalin)、苦杏仁酶(emulsin)、脂肪油等。【功能主治】活血祛瘀，润肠通便，止咳平喘。用于经闭，痛经，癥瘕痞块，跌扑损伤，肠燥便秘。桃仁与红花皆为活血祛瘀之药，作用均甚广泛，往往配合应用，唯桃仁善治肺痈肠痈，且有润肠通便之效；红花则善于活血调经。
[0008] 红花：【化学成分】含红花甙、新红花甙、红花醌甙、红花多糖、棕榈酸、肉桂酸、月桂酸。【性味】性温，味辛。【功能主治】活血通经，散淤止痛，用于闭经，痛经，恶露不行，症瘕痞块，跌扑损伤，疮疡肿痛。
[0009] 川芎：味辛，性温。归肝、胆、心包经。【功能与主治】活血行气，祛风止痛。用于安抚神经，正头风头痛，症瘕腹痛，胸胁刺痛，跌扑肿痛，头痛，风湿痹痛。
[0010] 柴胡：清虚热中药，用于感冒发热、寒热往来、疟疾、肝郁气滞、胸肋胀痛、脱肛、子宫脱落、月经不调。性味归经：性微寒、味苦、辛、归肝经、肺经、脾经。功能：透表泄热，疏肝解郁，升举阳气。主治：感冒发热、寒热往来、疟疾，肝郁气滞，胸肋胀痛，脱肛，子宫脱落，月经不调。
[0011] 当归：【化学成分】含基本内酯、正丁烯酰内酯、阿魏酸、烟酸、蔗糖和多种氨基酸，以及倍半萜类化合物等。【性味归经】性温，昧甘、辛。归肝、心、脾经。【功能主治】补血活血，调经止痛，润肠通便。用于血虚萎黄、眩晕心悸、月经不调、经闭痛经、虚寒腹痛、肠燥便秘、风湿痹痛、跌扑损伤、痈疽疮疡。
[0012] 白芍：根含芍药甙、牡丹酚、芍药花甙，苯甲酸约1. 07%、挥发油、脂肪油、树脂、鞣质、糖、淀粉、粘液质、蛋白质、3 -谷留醇和三萜类。另四川产者含一种酸性物质，对金黄色葡萄球菌有抑制作用。
[0013] 地黄：味甘性微温，归肝、肾经，有养血滋阴，补精益髓的功效，适用于血虚证，妇女月经不调，肝肾阴虚证，消渴证，精血亏虚证等。熟地为滋补肝肾的重要药物，不仅能够养血滋阴，而且能够生精填髓。中医认为精血是人体内最根本的物质基础，精血充足则肝肾功能正常，机体表现出强健功能状态。反之，人体精血不足则出现头晕目眩，腰膝酸软，耳聋耳 鸣，须发早白，未老先衰，性功能减退等等。
[0014] 香附：莎草科植物莎草Cyperus rotundus L.的干燥根莖。理气解郁；调经止痛；安胎。主胁肋胀痛；乳房胀育；疝气疼痛；月经不调；脘腹痞满疼痛；嗳气吞酸，呕恶；经行腹痛；崩漏带下；胎动不安。用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，胸脘痞闷，寒疝腹痛，乳房胀痛，月经不调，经闭痛经。
[0015] 炒积壳：芸香科植物酸橙Citrus aurantium L.及其栽培变种的干燥未成熟果实。性味苦；酸；性微寒归经：肺；脾；肝；胃；大肠经功能主治：胸隔痞满；胁肋胀痛；食积不化；脘腹胀满；下痢后重；脱肛；子宫脱垂。
[0016] 郁金香：郁金香汁通过阳离子及阴离子交换树脂后，对金黄色葡萄球菌仍有抗菌作用。莖和叶的酒精提取液，对Bacillus cereus mycoides有抗菌作用，其活性成分中含多种氨基酸。郁金香甙ABC对枯草杆菌有抑制作用。郁金香汁通过阳离了及阴离子交换树脂后，对金黄色葡萄球菌仍有抗菌作用。莖和叶的酒精提取液，对Bacillus cereus mycoides有抗菌作用，其活性成分中含有多种氨基酸。
[0017] 甘草：性平，味甘，归十二经。有解毒、祛痰、止痛、解痉以至抗癌等药理作用。在中医上，甘草补脾益气，止咳润肺，缓急解毒，调和百药。
[0018] 本发明药物具有补血养血、活血消瘀、养阴生津、舒肝健脾、理气通血功效，用于经血不调、精神压力过重所致色斑；黄褐斑。
[0019] 本发明临床应用的典型病例：
[0020] 典型病例1.患者张少红，女，23岁，办公室职员，9月27日来诊，诉：近年来，感觉面部暗淡无光，有时爱发脾气，失眠多梦，月经也不照时，有时小腹冷痛，月经后错，心里总有说不出的不适，希望中医调理。经诊查，注患者面色黯淡、黑眼圈、鼻翼面旁有肝斑，舌质暗红，苔白腻。脉细等，症系：肝郁气滞，下焦虚冷，气血不调，血不上荣所致，治当以疏肝理气，调经温经，养血活血，气正则血上荣，即投以本发明药物治之，7天，症减过半，续服10余天症除，半年后复查，无复发，其远期效果较为理想。
[0021] 典型病例2.患者任珍，女，55岁，农民，9月24日来诊，诉十余年来，面色难看，失眠多梦，家务的繁重，总是感觉身体疲惫，月经量少，四肢凉、皮肤粗糙，在当地医生处用药，时轻时重，总难治愈也服用过中药，但疗效不称意，故经人介绍到我处就诊。查：舌质暗淡微红，苔薄白，脉细缓，面色灰暗无光泽，症系气血虚，肝脾不和，经血不调所致，治以养血调经，开郁顺气，补血活血，即投以以本发明药物治之，半月，病人症状减至过半，嘱其按疗程25天为限，服药3个疗程，每一个疗程中间隔I〜2周，以观后效，2年后复查，远期效果理
本巨
o
具体实施方式
[0022] 治疗黄褐斑的纯中药制剂，选用的原料 药材及重量组分分别是：黄芪15份、桃仁10份、红花6份、川弯6份、银柴胡8份、当归9份、炒白芍9份、地黄9份、香附9份、炒枳壳9份、郁金6份、炙甘草3份。
[0023] 本发明药物的制备方法：
[0024] 水煎提取法：步骤一）取黄芪15份、桃仁10份、红花6份、川弯6份、银柴胡8份、当归9份、炒白芍9份、地黄9份、香附9份、炒枳壳9份、郁金6份、炙甘草3份，制成药材饮片，置陶瓷煎煮器中，加水800ml，浸泡I—3小时，获得药材浸泡混合液；
[0025] 步骤二）、把步骤一）获得的药材浸泡混合液加热至沸，保持20—30分钟，过滤或沉降分离出煎液，获得一次煎液和药渣，备用；
[0026] 步骤三）、把步骤二）获得的药渣加水600——800ml再次煎煮，20——30分钟，过滤或沉降分离出二次煎液，药渣弃用；
[0027] 步骤四）、把步骤二、三）获得的一次煎液和二次煎液合并，获得合并煎液供内服饮用。
[0028] 主治：用于经血不调、精神压力过重所致色斑；黄褐斑。
[0029] 药物的用法：口服每次150ml，每日2次。
[0030] 注意事项：本品为内服制剂，孕妇及小儿禁服，服用期间忌食辛、辣、生、冷刺激性食物。
Claims (2)
1. 一种治疗黄褐斑的纯中药制剂，其特征在于，选用的原料药材及重量组分分别是: 黄芪15份、桃仁10份、红花6份、川芎6份、银柴胡8份、当归9份、炒白芍9份、地黄9份、 香附9份、炒积壳9份、郁金6份、炎甘草3份。
2.按照权利要求1所述的治疗黄褐斑的纯中药制剂，其特征在于，其制备方法是： 步骤一）取黄芪15份、桃仁10份、红花6份、川芎6份、银柴胡8份、当归9份、炒白芍9份、地黄9份、香附9份、炒枳壳9份、郁金6份、炙甘草3份，制成药材饮片，置陶瓷煎煮器中，加水800ml，浸泡I——3小时，获得药材浸泡混合液；步骤二）、把步骤一）获得的药材浸泡混合液加热至沸，保持20——30分钟，过滤或沉降分离出煎液，获得一次煎液和药渣，备用；步骤三)、把步骤二 )获得的药渣加水600——800ml再次煎煮，20——30分钟，过滤或沉降分离出二次煎液，药渣弃用；步骤四）、把步骤二、三）获得的一次煎液和二次煎液合并，获得合并煎液供内服饮用。
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| CN105596733A (zh) * | 2016-03-16 | 2016-05-25 | 烟台市蓝洋之草医药生物科技有限公司 | 一种中药制剂在制备治疗气滞血瘀型黄褐斑药物中的用途 |
| CN105641426A (zh) * | 2016-03-16 | 2016-06-08 | 烟台市蓝洋之草医药生物科技有限公司 | 一种治疗气滞血瘀型黄褐斑的中药制剂 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105596733A (zh) * | 2016-03-16 | 2016-05-25 | 烟台市蓝洋之草医药生物科技有限公司 | 一种中药制剂在制备治疗气滞血瘀型黄褐斑药物中的用途 |
| CN105641426A (zh) * | 2016-03-16 | 2016-06-08 | 烟台市蓝洋之草医药生物科技有限公司 | 一种治疗气滞血瘀型黄褐斑的中药制剂 |
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