CN113939733B - 多毛细管电泳装置、及样品分析方法 - Google Patents

多毛细管电泳装置、及样品分析方法 Download PDF

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Publication number
CN113939733B
CN113939733B CN201980097044.1A CN201980097044A CN113939733B CN 113939733 B CN113939733 B CN 113939733B CN 201980097044 A CN201980097044 A CN 201980097044A CN 113939733 B CN113939733 B CN 113939733B
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Prior art keywords
capillaries
sample
capillary
correction index
signal intensity
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Chinese (zh)
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CN113939733A (zh
Inventor
隅田周志
穴泽隆
藤冈满
山崎基博
中泽太朗
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Hitachi High Tech Corp
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Hitachi High Technologies Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44782—Apparatus specially adapted therefor of a plurality of samples

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201980097044.1A 2019-06-06 2019-06-06 多毛细管电泳装置、及样品分析方法 Active CN113939733B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410503547.7A CN118191073A (zh) 2019-06-06 2019-06-06 多毛细管电泳装置

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2019/022449 WO2020245961A1 (ja) 2019-06-06 2019-06-06 マルチキャピラリ電気泳動装置、及びサンプル分析方法

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CN202410503547.7A Division CN118191073A (zh) 2019-06-06 2019-06-06 多毛细管电泳装置

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CN113939733A CN113939733A (zh) 2022-01-14
CN113939733B true CN113939733B (zh) 2024-05-14

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CN202410503547.7A Pending CN118191073A (zh) 2019-06-06 2019-06-06 多毛细管电泳装置

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CN202410503547.7A Pending CN118191073A (zh) 2019-06-06 2019-06-06 多毛细管电泳装置

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US (1) US20220229013A1 (cg-RX-API-DMAC7.html)
JP (1) JP7261877B2 (cg-RX-API-DMAC7.html)
CN (2) CN113939733B (cg-RX-API-DMAC7.html)
DE (1) DE112019007287T5 (cg-RX-API-DMAC7.html)
GB (1) GB2599029B (cg-RX-API-DMAC7.html)
WO (1) WO2020245961A1 (cg-RX-API-DMAC7.html)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022130607A1 (ja) * 2020-12-18 2022-06-23 株式会社日立ハイテク キャピラリアレイ

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10206384A (ja) * 1997-01-16 1998-08-07 Kagaku Gijutsu Shinko Jigyodan マルチキャピラリー電気泳動装置
JP2000258392A (ja) * 1999-03-05 2000-09-22 Hitachi Ltd 電気泳動装置
EP1052504A2 (en) * 1999-05-12 2000-11-15 The Institute of Physical and Chemical Research Multi-capillary electrophoretic apparatus
CN102411024A (zh) * 2011-06-15 2012-04-11 公安部第一研究所 一种基于空间校正及光谱校正的毛细管阵列电泳检测方法
JP2012168138A (ja) * 2011-02-17 2012-09-06 Hitachi High-Technologies Corp 電気泳動装置
JP2014194362A (ja) * 2013-03-28 2014-10-09 Hitachi High-Technologies Corp 電気泳動装置
CN104870980A (zh) * 2012-12-17 2015-08-26 株式会社日立高新技术 基因型解析装置以及基因型解析方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6982029B2 (en) * 2001-05-07 2006-01-03 Spectramedix Llc Electrophoretic method and system having internal lane standards for color calibration
US8012327B2 (en) * 2006-01-16 2011-09-06 Hitachi High-Technologies Corporation Capillary electrophoresis apparatus and electrophoresis method
JP6350349B2 (ja) 2015-03-19 2018-07-04 株式会社島津製作所 キャピラリー電気泳動装置及びキャピラリー電気泳動による試料分析方法
WO2018156969A1 (en) * 2017-02-24 2018-08-30 Life Technologies Corporation Optical systems and methods for sample separation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10206384A (ja) * 1997-01-16 1998-08-07 Kagaku Gijutsu Shinko Jigyodan マルチキャピラリー電気泳動装置
JP2000258392A (ja) * 1999-03-05 2000-09-22 Hitachi Ltd 電気泳動装置
EP1052504A2 (en) * 1999-05-12 2000-11-15 The Institute of Physical and Chemical Research Multi-capillary electrophoretic apparatus
JP2012168138A (ja) * 2011-02-17 2012-09-06 Hitachi High-Technologies Corp 電気泳動装置
CN102411024A (zh) * 2011-06-15 2012-04-11 公安部第一研究所 一种基于空间校正及光谱校正的毛细管阵列电泳检测方法
CN104870980A (zh) * 2012-12-17 2015-08-26 株式会社日立高新技术 基因型解析装置以及基因型解析方法
JP2014194362A (ja) * 2013-03-28 2014-10-09 Hitachi High-Technologies Corp 電気泳動装置

Also Published As

Publication number Publication date
JP7261877B2 (ja) 2023-04-20
GB2599029A (en) 2022-03-23
DE112019007287T5 (de) 2022-04-14
CN113939733A (zh) 2022-01-14
JPWO2020245961A1 (cg-RX-API-DMAC7.html) 2020-12-10
GB2599029B (en) 2023-05-17
US20220229013A1 (en) 2022-07-21
GB202117085D0 (en) 2022-01-12
CN118191073A (zh) 2024-06-14
WO2020245961A1 (ja) 2020-12-10

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