CN113874019A - 用于治疗nash/nafld及相关疾病的包含作为glp-1r激动剂的苯并二氧杂环戊烯的组合 - Google Patents

用于治疗nash/nafld及相关疾病的包含作为glp-1r激动剂的苯并二氧杂环戊烯的组合 Download PDF

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CN113874019A
CN113874019A CN202080037376.3A CN202080037376A CN113874019A CN 113874019 A CN113874019 A CN 113874019A CN 202080037376 A CN202080037376 A CN 202080037376A CN 113874019 A CN113874019 A CN 113874019A
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China
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methyl
piperidin
carboxylic acid
benzodioxol
benzimidazole
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Pending
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CN202080037376.3A
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Chinese (zh)
Inventor
G·E·阿斯普内斯
S·W·巴格利
J·M·柯托
M·道林
D·J·埃德蒙斯
D·费尔南多
M·E·弗拉纳根
二木建太郎
D·A·格里菲斯
K·瓦尔
G·英格尔
W·焦
S·M·拉卡斯
Y·连
C·利伯拉基斯
A·T·隆德雷甘
A·M·马蒂奥韦茨
D·W·彼得罗夫斯基
R·B·鲁格里
K·维格尔斯沃斯
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Pfizer Inc
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Pfizer Inc
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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CN202080037376.3A 2019-05-20 2020-05-15 用于治疗nash/nafld及相关疾病的包含作为glp-1r激动剂的苯并二氧杂环戊烯的组合 Pending CN113874019A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962850133P 2019-05-20 2019-05-20
US62/850,133 2019-05-20
PCT/IB2020/054637 WO2020234726A1 (en) 2019-05-20 2020-05-15 Combinations comprising benzodioxol as glp-1r agonists for use in the treatment of nash/nafld and related diseases

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Publication Number Publication Date
CN113874019A true CN113874019A (zh) 2021-12-31

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US (1) US12611401B2 (https=)
EP (2) EP4578460A3 (https=)
JP (1) JP7672201B2 (https=)
CN (1) CN113874019A (https=)
AR (1) AR118965A1 (https=)
CA (1) CA3140972C (https=)
ES (1) ES3039586T3 (https=)
TW (1) TW202110446A (https=)
WO (1) WO2020234726A1 (https=)

Cited By (3)

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CN114728955A (zh) * 2019-11-29 2022-07-08 广东东阳光药业有限公司 Tropifexor的新晶型及其制备方法
CN114728954A (zh) * 2019-11-29 2022-07-08 广东东阳光药业有限公司 Tropifexor的新晶型及其制备方法
WO2024212742A1 (zh) * 2023-04-10 2024-10-17 上海研健新药研发有限公司 一种glp-1r激动剂，其制备方法和应用

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