CN1138468A - "Bibao", a medicine for treatment of rhinitis and its prepn. method - Google Patents
"Bibao", a medicine for treatment of rhinitis and its prepn. method Download PDFInfo
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- CN1138468A CN1138468A CN 95107221 CN95107221A CN1138468A CN 1138468 A CN1138468 A CN 1138468A CN 95107221 CN95107221 CN 95107221 CN 95107221 A CN95107221 A CN 95107221A CN 1138468 A CN1138468 A CN 1138468A
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- liquid
- nose
- rhinitis
- gallus domesticus
- extracting solution
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Abstract
A Chinese patent medicine for treating allergic rhinitis, acute or chronic rhinitis, atrophic rhinitis and nasosinusitis with effective rate of over 91% is prepared from 9 Chinese-medicinal materials such as Taihe chicken, chrysanthemum flower, dahurian angelica root, black plum, perilla leaf, etc. It can be applied orally or externally.
Description
The present invention relates to the pure Chinese medicine product that a kind of dietetic therapy product are used for rhinitis
Rhinitis is one of commonly encountered diseases in the world, does not form a kind of authoritative therapeutic scheme at present both at home and abroad as yet in treatment.Clinically routine treatments such as antihistaminic medicine, corticosteroid, agent of medium cytotostatic and blocking-up parasympathetic fibers that adopt, treatment is difficult to produce a desired effect more.The present invention is directed to the characteristics of incidence of rhinitis, adopt traditional Chinese medical science nose to treat (local treatment) and the dietary therapy of Chinese medicine (whole therapy) rhinitis is controlled, obtained effect preferably through a large amount of clinical trials.
The object of the invention is, development be used for nose treasured of rhinitis and preparation method thereof, be to adopt pure Chinese medicine Gallus Domesticus, Flos Chrysanthemi, the Radix Angelicae Dahuricae, Fructus Mume, Folium Perillae, Semen Sinapis, Flos Caryophylli, Herba Moslae, Radix Glycyrrhizae etc. to be mixed with the external of various dosage forms, nose treasured for oral administration, through a large amount of clinical practice test, to allergic rhinitis, acute and chronic rhinitis, atrophic rhinitis, sinusitis, etc. the equal effective percentage of various rhinitis more than 91%.
A kind of nose treasured that is used for rhinitis of the present invention and preparation method thereof is to have adopted traditional Chinese medical science nose to treat (local treatment) and the dietary therapy of Chinese medicine (whole therapy) various rhinitis are controlled treatment.Traditional Chinese medical science nose is treated: be Chinese traditional medicine principle according to " BITONG hundred networks ", and the nasal cavity dispensing, by the absorption of nasal cavity blood capillary, nerve stimulation and brain are regulated, and pulmonary absorbs, the action pathway of and adjacent tissue local to nasal cavity and generation effect.The dietary therapy of Chinese medicine: many by the characteristics due to lung qi deficiency and coldness, exterior deficiency, ailment said due to cold or exposure love lung, mechanism of qi retardance, Yong Sai nose key, the spleen deficiency of kidney-QI of holding concurrently at rhinitis more, the medicinal and edible Chinese medicine of selecting the health ministry approval for use is by the oral liquid form administration, sensible with precious lung, expelling wind and cold, heat-clearing and toxic substances removing, invigorating the spleen and benefiting QI the kidney invigorating, raise immunity, strengthen phagocytic activity of leukocytes, thereby treating both the principal and secondary aspects of a disease reaches the purpose of healing.
A kind of nose treasured that is used for rhinitis of the present invention and preparation method thereof, it mainly is to adopt pure Chinese medicine Gallus Domesticus, Flos Chrysanthemi, the Radix Angelicae Dahuricae, Fructus Mume, Folium Perillae, Semen Sinapis, Flos Caryophylli, Herba Moslae, Radix Glycyrrhizae to make various dosage forms, and its each component proportioning is (being mixed with 1000 milliliters with weight in grams is radix): Gallus Domesticus extracting solution 20-50g, Flos Chrysanthemi 60-90g, Radix Angelicae Dahuricae 60-110g, Fructus Mume 100-40g, Folium Perillae 100-70g, Semen Sinapis 40-80g, Flos Caryophylli 10-30g, Herba Moslae 100-40g, Radix Glycyrrhizae 50-100g, sucrose 100-200g, distilled water surplus.Preparation method is: at first with Flos Chrysanthemi, the Radix Angelicae Dahuricae, Fructus Mume, Folium Perillae, Semen Sinapis, Flos Caryophylli, Herba Moslae, Radix Glycyrrhizae eight flavor medicine distillations, extraction, A liquid is made in volatilization; Medicinal residues are decocted with water again and extract 3 times, the time is respectively (1.5,1.0,0.5 hours), merges 3 times extracting solution, filters to concentrate; Add ethanol again and stir, supernatant is drawn in cold preservation 48 hours, reclaims ethanol and does not promptly get B liquid to having the alcohol flavor, concentrating; Refabrication Gallus Domesticus extracting solution can obtain Gallus Domesticus extracting solution C liquid with Gallus Domesticus with decoction and alcohol sedimentation technique and acid hydrolyzation.Add the spissated B liquid of medicinal residues in the A liquid with eight flavor medicines extractions, sterilization, packing make the precious nasal drop of external nose.The A liquid that eight flavor medicines are extracted again, the B liquid after medicinal residues concentrate, Gallus Domesticus extracting solution C mixing and stirring, add the sucrose mix homogeneously, add the surplus distilled water again and be mixed with 1000 milliliters, transfer PH4.5-5.5,110 ℃ of hot pressing, make the precious oral liquid for oral administration of nose through the packing in 30 minutes of sterilizing.
A kind of nose treasured that is used for rhinitis of the present invention and preparation method thereof, through a large amount of clinical trials, adopting two groups of contrast treatments, respectively to 298 examples, is many with the young and the middle aged, the course of disease was many in 2 months-5 years, treatment group simple rhinitis 31 examples, hypertrophic rhinitis 28 examples, allergic rhinitis 225 examples, atrophic rhinitis's 8 examples, sinusitis are 6 examples.It is example that matched group selects allergic rhinitis.Therapeutic Method adopts the nose treasured of development to take oral liquid-Ri orally 3 times to the treatment group, and a 20-30ml uses the precious nasal drop of external nose 3-4 time on the 1st simultaneously, and each 2-3 drips, and one month one course of treatment, it the results are shown in Table:
| Group | The example number | Treat n % in the recent period | Produce effects n % | Effective n % | Invalid n % | Total effective rate n % |
| Treatment group matched group | ??298 ???68 | ??87????29.19 ???5????7.35 | ??66????22.14 ??17????25 | ???119????39.93 ????34????50 | ????26??????8.72 ????12?????17.65 | ??????272?????91.27 ???????56?????82.35 |
Conclusion: a kind of precious and formulation Preparation Method of nose that is used for rhinitis of the present invention is formulated with natural Chinese medicines.Characteristics such as the effective percentage that adopts the precious treatment of nose as seen from the table has specimen Lian Zhi more than 91%, and indication is wide.And the detection of process relevant department meets state health standards.
Embodiment 1:
Flos Chrysanthemi 60 gram, the Radix Angelicae Dahuricae 85 grams, Fructus Mume 40 grams, Folium Perillae 100 grams, Semen Sinapis 40 grams, Flos Caryophylli 30 grams, Herba Moslae 70 grams, Radix Glycyrrhizae 60 grams are distilled, extract, that A liquid is made in volatilization is stand-by; Again medicinal residues are decocted with water and extract 3 times, time is (1.5,1.0,0.5 hours) respectively, merge 3 times extracting solution, filtration is concentrated into 450ml (relative density 1.10-1.2/25 ℃) and adds the stirring of 60% ethanol, cold preservation 48 hours, draw supernatant, reclaim ethanol to there not being the alcohol flavor, being concentrated into 400ml (relative density 1.12-1.18/25 ℃), promptly to get B liquid stand-by.It is stand-by again Gallus Domesticus 20 grams to be made Gallus Domesticus extracting solution C liquid with decoction and alcohol sedimentation technique and acid hydrolyzation; Add the B liquid after medicinal residues concentrate then in the A liquid that eight flavor medicines are extracted, through sterilization, packing makes the precious nasal drop of external nose.B liquid after A liquid, the medicinal residues that eight flavor medicines are extracted concentrate again, Gallus Domesticus extracting solution C liquid mixing and stirring, add 100 gram sucrose mix homogeneously, add the surplus distilled water again and be mixed with 1000 milliliters, accent PH4.5-5.5, the packing in 30 minutes of sterilizing under 115 ℃ of hot pressing make the precious oral liquid for oral administration of nose.
Embodiment 2:
Flos Chrysanthemi 80 gram, the Radix Angelicae Dahuricae 60 grams, Fructus Mume 100 grams, Folium Perillae 70 grams, Semen Sinapis 60 grams, Flos Caryophylli 20 grams, Herba Moslae 100 grams, Radix Glycyrrhizae 80 grams are distilled, extract, that A liquid is made in volatilization is stand-by; Again medicinal residues are decocted with water and extract 3 times, time is (1.5,1.0,0.5 hours) respectively, merge 3 times extracting solution, filtration is concentrated into 450ml (relative density 1.10-1.2/25 ℃) and adds the stirring of 60% ethanol, cold preservation 48 hours, draw supernatant, reclaim ethanol to there not being the alcohol flavor, being concentrated into 400ml (relative density 1.12-1.18/25 ℃), promptly to get B liquid stand-by.It is stand-by again Gallus Domesticus 35 grams to be made Gallus Domesticus extracting solution C liquid with decoction and alcohol sedimentation technique and acid hydrolyzation, adds the B liquid after medicinal residues concentrate then in the A liquid that eight flavor medicines are extracted, and through sterilization, packing makes the precious nasal drop of external nose.B liquid after A liquid, the medicinal residues that eight flavor medicines are extracted concentrate again, Gallus Domesticus extracting solution C liquid mixing and stirring, add 150 gram sucrose mix homogeneously, add the surplus distilled water again and be mixed with 1000 milliliters, accent PH4.5-5.5, the packing in 30 minutes of sterilizing under 115 ℃ of hot pressing make the precious oral liquid for oral administration of nose.
Embodiment 3:
Flos Chrysanthemi 90 gram, the Radix Angelicae Dahuricae 110 grams, Fructus Mume 70 grams, Folium Perillae 85 grams, Semen Sinapis 80 grams, Flos Caryophylli 10 grams, Herba Moslae 40 grams, Radix Glycyrrhizae 100 grams are distilled, extract, that A liquid is made in volatilization is stand-by; Again medicinal residues are decocted with water and extract 3 times, time is (1.5,1.0,0.5 hours) respectively, merge 3 times extracting solution, filtration is concentrated into 450ml (relative density 1.10-1.2/25 ℃) and adds the stirring of 60% ethanol, cold preservation 48 hours, draw supernatant, reclaim ethanol to there not being the alcohol flavor, being concentrated into 400ml (relative density 1.12-1.18/25 ℃), promptly to get B liquid stand-by.It is stand-by again Gallus Domesticus 50 grams to be made Gallus Domesticus extracting solution C liquid with decoction and alcohol sedimentation technique and acid hydrolyzation, adds the B liquid after medicinal residues concentrate then in the A liquid that eight flavor medicines are extracted, and through sterilization, packing makes the precious nasal drop of external nose.B liquid after A liquid, the medicinal residues that eight flavor medicines are extracted concentrate again, Gallus Domesticus extracting solution C liquid mixing and stirring, add sucrose 200 gram mix homogeneously, add the surplus distilled water again and be mixed with 1000 milliliters, accent PH4.5-5.5, the packing in 30 minutes of sterilizing under 115 ℃ of hot pressing make the precious oral liquid for oral administration of nose.
Claims (4)
1, a kind of dietetic therapy product nose treasured that is used for rhinitis and preparation method thereof, it is characterized in that it is to be made by pure Chinese medicine Gallus Domesticus, Flos Chrysanthemi, the Radix Angelicae Dahuricae, Fructus Mume, Folium Perillae, Semen Sinapis, Flos Caryophylli Herba Moslae, Radix Glycyrrhizae, its each component proportioning is (being mixed with 1000 milliliters with weight in grams is radix):
Gallus Domesticus extracting solution 20-50g
Flos Chrysanthemi 60-90g
Radix Angelicae Dahuricae 60-110g
Fructus Mume 100-40g
Folium Perillae 100-70g
Semen Sinapis 40-80g
Flos Caryophylli 10-30g
Herba Moslae 100-40g
Radix Glycyrrhizae 50-100g
Sucrose 100-200g
Distilled water surplus
2, a kind of nose treasured that is used for rhinitis according to claim 1 and preparation method thereof is characterized in that, at first with Flos Chrysanthemi, the Radix Angelicae Dahuricae, Fructus Mume, Folium Perillae, Semen Sinapis, Flos Caryophylli, Herba Moslae, Radix Glycyrrhizae eight flavor medicine distillations, extracts volatilization and makes A liquid; Medicinal residues are decocted with water again and extract 3 times, the time is respectively (1.5,1.0,0.5 hours), merges 3 times extracting solution, filters to concentrate; Add ethanol again and stir, supernatant is drawn in cold preservation 48 hours, reclaims ethanol and does not promptly get B liquid to having the alcohol flavor, concentrating; Refabrication Gallus Domesticus extracting solution can obtain Gallus Domesticus extracting solution C liquid with Gallus Domesticus with decoction and alcohol sedimentation technique and acid hydrolyzation.
According to claim 1,2 described a kind of nose treasured that are used for rhinitis and preparation method thereof, it is characterized in that 3, add the spissated B liquid of medicinal residues in the A liquid with eight flavor medicines extractions, sterilization, packing make the precious nasal drop of external nose.
4, according to claim 1,2 described a kind of nose treasured that are used for rhinitis and preparation method thereof, it is characterized in that, with the A liquid that eight flavor medicines extract, the B liquid after medicinal residues concentrate, Gallus Domesticus extracting solution C liquid mixing and stirring, add the sucrose mix homogeneously, add the surplus distilled water again and be mixed with 1000 milliliters, transfer pH value 4.5-5.5,115 ℃ of hot pressing, through sterilizing 30 minutes, packing makes the precious oral liquid for oral administration of nose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95107221 CN1138468A (en) | 1995-06-17 | 1995-06-17 | "Bibao", a medicine for treatment of rhinitis and its prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 95107221 CN1138468A (en) | 1995-06-17 | 1995-06-17 | "Bibao", a medicine for treatment of rhinitis and its prepn. method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1138468A true CN1138468A (en) | 1996-12-25 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 95107221 Pending CN1138468A (en) | 1995-06-17 | 1995-06-17 | "Bibao", a medicine for treatment of rhinitis and its prepn. method |
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| Country | Link |
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| CN (1) | CN1138468A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7384654B2 (en) | 2004-02-05 | 2008-06-10 | Access Business Group International Llc | Anti-Allergy composition and related method |
| EP2494868A4 (en) * | 2009-10-26 | 2015-03-11 | Ciencia Intra Vegetal S L | Method for the extraction and hydrolysis of any protein substance, natural auxins and polyphenols from sources of plant origin, and resulting product |
-
1995
- 1995-06-17 CN CN 95107221 patent/CN1138468A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7384654B2 (en) | 2004-02-05 | 2008-06-10 | Access Business Group International Llc | Anti-Allergy composition and related method |
| US7384656B2 (en) | 2004-02-05 | 2008-06-10 | Access Business Group International Llc | Anti-allergy composition and related method |
| EP2494868A4 (en) * | 2009-10-26 | 2015-03-11 | Ciencia Intra Vegetal S L | Method for the extraction and hydrolysis of any protein substance, natural auxins and polyphenols from sources of plant origin, and resulting product |
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