CN116726115A - Traditional Chinese medicine composition for reducing blood fat and losing weight and preparation method thereof - Google Patents

Traditional Chinese medicine composition for reducing blood fat and losing weight and preparation method thereof Download PDF

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CN116726115A
CN116726115A CN202310881638.XA CN202310881638A CN116726115A CN 116726115 A CN116726115 A CN 116726115A CN 202310881638 A CN202310881638 A CN 202310881638A CN 116726115 A CN116726115 A CN 116726115A
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chinese medicine
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spleen deficiency
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顾水祥
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Abstract

The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for reducing blood fat and losing weight and a preparation method thereof, wherein the traditional Chinese medicine composition comprises the following raw materials: corn silk, coix seed, poria cocos, rhizoma alismatis, red bean and the like, wherein the traditional Chinese medicine composition comprises a traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and damp-heat, a traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and turbid cold-damp, a traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and turbid cold-heat, and a traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and turbid damp-heat, and raw materials of the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and damp-heat comprise vinegar-processed rheum officinale, gynostemma pentaphylla, herba artemisiae capillaris, motherwort and the like; the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold and dampness comprises herba lycopi, semen plantaginis, orange peel, rhizoma atractylodis and the like, and the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold and heat and mixed type of spleen deficiency, phlegm stasis, turbid cold and dampness comprises vinegar-processed rheum officinale, gynostemma pentaphylla, orange peel, rhizoma atractylodis and the like; the invention aims to provide a traditional Chinese medicine composition for reducing blood fat and losing weight and a preparation method thereof, and the matching modes of different traditional Chinese medicine compositions are selected according to the differences of basic symptoms, so that the traditional Chinese medicine composition is simple and practical and is convenient to popularize and apply.

Description

Traditional Chinese medicine composition for reducing blood fat and losing weight and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for reducing blood fat and losing weight and a preparation method thereof.
Background
The traditional Chinese medicine has long history of understanding obesity, namely obesity people are fat people, paste people and honour people, but the understanding aspect is fragmented, a unified and systematic theoretical system is not formed, and the etiology aspect considers that the obesity people are related to factors such as physique, endowment, improper diet, good and quiet movement, seven emotions, and the like, and the pathogenesis aspect is also profound 32429. "Engineer" considers that all wets and swells are spleen ", so spleen deficiency and malnutrition are important reasons for causing obesity, lidong is considered as" greasy and thick taste, phlegm and saliva are produced ", zhu Danxi is considered as" fat white people are rich in phlegm and excessive dampness "," fat people are heavy and idle and are qi deficiency ", shen Jinao is considered as" fat people are qi deficiency ", fu Qingzhu is considered as" woman physique is rich, food is thick taste, phlegm and wet are endogenous "," fat people are rich in phlegm, qi deficiency is also caused by deficiency, qi cannot be transported and transformed, so phlegm is produced ", wang Ang is considered as" spleen and stomach are both deficient and cannot be eaten and thin, or are lack of food and fat, and are fat and limbs are not lifted "; "fat man shape is full of qi and qi deficiency"; the disease causes of the disease are mainly considered from the aspects of phlegm-dampness, stomach heat, spleen deficiency, qi deficiency and the like, and the disease causes cannot be completely true. The syndrome type classification is five-flower eight-door, different experts have different classifications, more than ten, less than five and six, and even no unified and standard treatment scheme is formed.
Wang Qiguo the university of medical staff, written in the Chinese medicine treatment of 62 refractory diseases, divides obesity into the following five syndromes: (1) spleen deficiency and damp obstruction; (2) stomach heat and dampness obstruction type; (3) turbid phlegm retention; (4) spleen-kidney yang deficiency; (5) yin deficiency with internal heat. Li Dian the main code of the university of Gui medical staff, the book of the theory of turbid toxin of traditional Chinese medicine, divides obesity into the following nine syndromes: (1) food stagnation; (2) excessive stomach heat; (3) stomach heat and dampness obstruction type; (4) liver depression and qi stagnation; (5) turbid toxin accumulated in the body; (6) qi stagnation and blood stasis; (7) spleen deficiency and damp obstruction; (8) deficiency of lung-spleen qi; (9) spleen-kidney yang deficiency. The Chinese patent medicine for reducing weight has the products of lipid-lowering and weight-reducing tablets, toxin-expelling and lipid-removing capsules, weight-reducing and fat-reducing pills and the like, and the true pathogenesis of obesity is not in the middle-jiao from the aspect of the formula, so the clinical curative effect is not very satisfactory. The reason for this is that the complex pathogenesis of obesity is not really known and mastered, the intrinsic nature of the complex constitution of multiple pathogenesis of obesity is not known and revealed, and the formulation is not accurate, so that the efficient formulation for treating the obesity with the complex constitution of multiple pathogenesis is not developed so far, and therefore, the curative effect of various weight-losing medicaments sold on the market at present is not good.
Obesity is related to physique, but the etiology and pathogenesis of obesity and the classification of physique are very disordered, so that doctors and patients cannot follow, no practical and operable scheme and method exist until now, and the inventor conducts intensive research and long-term clinical practice observation and summary on the physique and pathogenesis of obesity according to the traditional Chinese medicine theory, so that obesity is a multi-pathogenesis composite physique disease. Obesity is divided into three complex body types, namely positive complex body type obesity, negative complex body type obesity and mixed complex body type obesity:
(1) Positive complex obesity is called spleen deficiency, phlegm stasis and damp-heat type obesity, and has the clinical manifestations that: obesity, younger age, good appetite, dry mouth and bitter taste, halitosis, acne, normal or dry stool or constipation or unsmooth stool, harder abdomen touch, yellow or yellow greasy tongue coating, deep or smooth or thin or astringent sublingual vein or purple or varicose vein, female or small menstrual flow and dark color;
(2) The obesity with negative complex constitution is called spleen deficiency, phlegm stasis and cold dampness type obesity, and has the clinical manifestations that: obesity, age bias, general or not too much diet, drowsiness and debilitation, liking and aversion to movement, debilitation aggravated even asthma, general normal or loose stool for several times a day, or dry before loose stool or unsmooth stool, soft and drooping abdomen touch, swollen tongue with teeth marks, white or greasy or slippery coating, purple or curved tongue vein, deep or astringent pulse, female or reduced or disturbed menstruation, dark color;
(3) The mixed composite obesity is called spleen deficiency, phlegm stasis, turbid dampness and cold heat mixed obesity, and has the clinical manifestations that: obesity, other clinical manifestations are poor distinction between the two, drowsiness and debilitation, normal appetite, dry mouth and bitter taste, bad breath, loose stool or knots or sticky or normal stool, pale red tongue with teeth marks, white greasy or yellow greasy or thick greasy coating, sublingual veins or purple or curved and tense tongue, female or small menstrual flow, dark color, deep or astringent or thin pulse.
Pathogenesis analysis: the traditional Chinese medicine considers that spleen governs transportation and transformation, is a source of qi and blood biochemistry, so spleen deficiency can cause qi and blood double diseases, spleen deficiency causes disorder of transportation and transformation of food entering human body, water is not transformed into dampness, food is not transformed into food stagnation, phlegm, dampness, turbidity and blood stasis are generated, qi system represents phlegm-dampness, and blood system represents turbid blood stasis. The inventor creatively proposes only three multi-pathogenesis compound physical type obesity according to the degree of spleen deficiency and pathogenic factor excess and the difference of cold and heat disease, namely yang-deficiency and phlegm-stasis damp-heat type obesity (called spleen deficiency and phlegm-stasis and damp-heat type obesity), negative compound physical type obesity (called spleen deficiency and phlegm-stasis and cold-damp type obesity), mixed compound physical type obesity (called spleen deficiency and phlegm-stasis and damp-turbidity and cold-heat type obesity), and the obesity is a compound physical disease with five pathogenesis coexistence of spleen deficiency, phlegm, dampness, turbidity and blood stasis according to the difference of spleen deficiency and pathogenic factor excess and cold and heat disease simultaneously with other clinical manifestations of the disease, the pathogenesis is that qi and blood are both deficient and excessive and have cold and heat disease characteristics, phlegm-dampness in the qi system and turbid blood stasis in the blood system are extracted for the first time, the treatment must be simultaneously considered, the syndrome classification of the five flowers and eight doors at present is firstly generalized into simple and practical operability, so far no people can group the basic constitution of five basic pathogenesis of obesity (spleen deficiency, phlegm, dampness, turbidity and stasis), and meanwhile, an obesity body distinguishing formula is constructed according to the difference of the disease characteristics of cold, heat and cold and heat, thereby solving the problems of obesity body distinguishing and weight losing, treating both principal and secondary aspects of the disease, changing the multi-pathogenesis complex constitution of obesity, avoiding rebound and providing an innovative scheme for diagnosis and treatment of obesity.
In view of this, the present invention has been proposed.
Disclosure of Invention
(one) solving the technical problems
Aiming at the problems in the prior art, the invention aims to provide a traditional Chinese medicine composition for reducing blood fat and losing weight and a preparation method thereof, and the matching modes of different traditional Chinese medicine compositions are selected according to the differences of basic symptoms, so that the traditional Chinese medicine composition is simple and practical and is convenient to popularize and apply.
(II) technical scheme
In order to achieve the above purpose, the present invention provides the following technical solutions: a traditional Chinese medicine composition for reducing blood fat and losing weight is used for treating spleen deficiency, phlegm stasis, damp heat type obesity, spleen deficiency, phlegm stasis, cold dampness type obesity and spleen deficiency, phlegm stasis, damp turbidity, cold heat type mixed type obesity;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid damp and heat comprises raw materials including corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, rhizoma alismatis and red bean, vinegar-processed rheum officinale, gynostemma pentaphylla, magnolia officinalis, semen cassiae, herba artemisiae capillaris and herba leonuri;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and cold dampness comprises raw materials including corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, rhizoma alismatis and red bean, herba lycopi, semen plantaginis, astragalus membranaceus, bighead atractylodes rhizome, orange peel and rhizoma atractylodis;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat and impurity symptoms comprises corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, rhizoma alismatis and red bean, vinegar processed rheum officinale, gynostemma pentaphylla, magnolia officinalis, semen cassiae, herba artemisiae capillaries, herba leonuri, herba lycopi, semen plantaginis, astragalus membranaceus, bighead atractylodes rhizome, orange peel and rhizoma atractylodis.
Preferably, the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid damp-heat type obesity comprises the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-50 parts of poria cocos, 10-60 parts of lotus leaf, 5-50 parts of rhizoma alismatis, 10-60 parts of red bean, 5-30 parts of vinegar-processed rheum officinale, 10-30 parts of gynostemma pentaphylla, 5-30 parts of magnolia officinalis, 5-30 parts of semen cassiae, 5-30 parts of herba artemisiae capillaris and 10-60 parts of motherwort.
Preferably, the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and cold dampness type obesity is prepared from the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 10-60 parts of red bean, 5-30 parts of radish seed, 10-50 parts of poria cocos, 10-50 parts of herba lycopi, 5-50 parts of semen plantaginis, 10-50 parts of astragalus membranaceus, 5-30 parts of bighead atractylodes rhizome, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 5-50 parts of rhizoma alismatis, 5-30 parts of orange peel and 3-30 parts of rhizoma atractylodis.
Preferably, the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold and heat mixed obesity comprises the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 10-50 parts of poria cocos, 5-50 parts of rhizoma alismatis, 10-60 parts of red bean, 5-30 parts of vinegar processed rheum officinale, 10-30 parts of gynostemma pentaphylla, 5-30 parts of magnolia officinalis, 5-30 parts of semen cassiae, 5-30 parts of herba artemisiae capillaris, 10-60 parts of leonurus, 10-50 parts of herba lycopi, 5-50 parts of semen plantaginis, 10-50 parts of astragalus membranaceus, 5-30 parts of bighead atractylodes rhizome, 5-30 parts of orange peel and 3-30 parts of rhizoma atractylodis.
The traditional Chinese medicine composition for reducing blood fat and losing weight of any one of the above, further comprises a preparation method of the traditional Chinese medicine composition for reducing blood fat and losing weight, comprising the following steps: weighing raw materials according to the weight parts, drying the obtained raw materials, uniformly mixing, grinding into powder, sieving with a 50-100 mesh medicine sieve to obtain medium powder, sterilizing for 8 hours under an ultraviolet sterilizing lamp to obtain an intermediate, and preparing the intermediate into an oral preparation.
Preferably, the oral preparation is a tablet, a dispersing agent, a soft capsule, a granule, a pill, a dripping pill, a gel or an oral liquid preparation.
Preferably, the preparation process of the tablets in the oral preparation is as follows: selecting an intermediate, adding gypsum powder, common auxiliary materials and an adhesive, mixing, granulating, drying, adding a lubricant, uniformly mixing, granulating, and tabletting to obtain tablets; the common auxiliary materials are one or more than two of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; the adhesive is one of distilled water or 30% -70% ethanol solution; the lubricant is one of magnesium stearate 0.1-1%, talcum powder 0.1-3% or micro silica gel 0.1-0.3%.
Preferably, the preparation process of the soft capsule in the oral preparation is as follows: selecting an intermediate, adding 1% -15% of polyethylene glycols, a plasticizer, a disintegrating agent, curcumin, ferric oxide, a wetting agent and a suspending agent, uniformly mixing, and filling into a soft capsule; the plasticizer is one of glycerol or polyalcohol; the disintegrating agent is one of dry starch or effervescent disintegrating agent; the wetting agent is one of 30% -70% ethanol or liquid paraffin; the suspending agent is one of beeswax, aluminum monostearate or ethyl cellulose.
(III) beneficial effects
Compared with the prior art, the invention has the following beneficial effects:
(1) The invention carries out intensive and comprehensive research from pathogenesis of the obesity, creatively proposes to divide the obesity into three multi-pathogenesis compound constitution types and provides three associated traditional Chinese medicine compositions; namely, the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold and damp type and the traditional Chinese medicine group for treating spleen deficiency, phlegm stasis, turbid cold and damp type can be selected by a patient according to the clinical manifestations of the patient (wherein the traditional Chinese medicine group for treating spleen deficiency, phlegm stasis, turbid cold and damp type is the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold and damp type and the traditional Chinese medicine group for treating spleen deficiency, phlegm stasis, turbid cold and damp type is the traditional Chinese medicine composition for treating spleen deficiency, the weight ratio of the same medicine is the maximum ratio of one of the traditional Chinese medicine compositions;
(2) The inventor considers from the perspective of traditional Chinese medicine that obesity is not only qi-division disease, but also blood-division disease, and is qi-blood double disease; phlegm dampness exists in qi system, turbid blood stasis exists in blood system, spleen deficiency is the root, and qi and blood, deficiency and excess, cold and heat are integrated together; according to the difference of spleen deficiency degree, pathogenic excess and cold and heat degree, the invention carries out innovation and livestock classification which accords with clinical practical operation, has simple and scientific typing and is practical and convenient for future development and implementation, the traditional Chinese medicine composition provided by the invention has reasonable compatibility, is matched with pathogenesis, combines five causes of adiposis (spleen deficiency, phlegm, dampness, turbidity and blood stasis) with different pathogeny of cold and heat, develops an innovative special prescription for treating spleen deficiency, phlegm stasis and damp-heat type, and has the effects of clearing heat, resolving dampness, activating blood, resolving stasis, strengthening spleen, eliminating turbidity and reducing fat and losing weight; the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and cold dampness has the effects of strengthening spleen, eliminating dampness, activating blood, dissolving stasis, dispelling cold, eliminating turbid pathogen, reducing lipid and losing weight; the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat staggering has the effects of strengthening spleen, resolving dampness, activating blood, resolving stasis, dispelling cold, clearing heat, resolving turbidity, resolving stasis, reducing fat and losing weight;
(3) The invention adopts the raw materials with homology of medicine and food, has no side effect, has better treatment effect on obesity, can correct obesity constitution, can regulate body and reduce weight simultaneously, has no rebound, is simple and practical, and is convenient to popularize and use; and the composition is equally suitable for childhood obesity;
(4) On the basis of ensuring the treatment effect of the original traditional Chinese medicine, the invention provides the preparation methods of the tablets and the soft capsules for the convenience of storage, carrying and taking of patients, can be directly taken with water, is safe and sanitary, is convenient to carry and store, is easy to produce and sell, and changes the situation of complicated taking method of the traditional Chinese medicine preparation.
Detailed Description
The technical solutions of the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention, and it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The pharmacology of the traditional Chinese medicine in the traditional Chinese medicine composition is as follows:
gynostemma pentaphylla: bitter, sweet and cold, replenishing qi to invigorate the spleen, resolving phlegm to arrest cough, clearing heat and detoxicating.
Corn silk: sweet, flat, induce diuresis to alleviate edema, induce diuresis to alleviate jaundice.
Semen plantaginis: sweet and slightly cold. Induce diuresis to treat stranguria, drain dampness to stop diarrhea, clear liver to improve vision, clear lung-heat to resolve phlegm. The long-term taking of the wine can reduce weight and resist fatigue.
Hawthorn fruit: acid, sweet, slightly warm. Promoting digestion, invigorating stomach, promoting qi circulation, and dispelling blood stasis. Food retention is removed, and internal stagnation is eliminated. For spleen deficiency and damp-heat, promote digestion and remove food retention, and promote urination and defecation. Modern pharmacological researches have shown that haw has the effects of dilating blood vessel, reducing blood lipid, lowering blood pressure, strengthening heart, contracting uterus, resisting bacteria, tranquilizing mind, etc. Fatty acid contained in hawthorn can promote fat digestion.
White atractylodes rhizome: pungent, warm, bitter and sweet. Invigorating spleen, invigorating qi, eliminating dampness, promoting diuresis, relieving sweating, and preventing miscarriage. Long-term administration of the medicine can reduce weight, prolong life and avoid hunger. Strengthen spleen and stomach, promote fever, drowsiness of limbs, no desire to open eyes, and slow and limpid sleep, and poor appetite. Vinegar processed rheum officinale: the purgation action is slowed down, mainly to remove food retention and remove blood stasis.
Semen cassiae: sweet, bitter, salty, slightly cold. Clear heat and improve eyesight, moisten intestines and relieve constipation. Modern pharmacological researches have shown that cassia seed has the effects of lowering blood pressure, lowering serum cholesterol, inducing diarrhea, resisting bacteria and the like.
Rhizoma atractylodis: pungent, bitter and warm. Dry dampness, invigorate spleen, expel wind, dispel cold, improve eyesight. Spleen-entering can raise yang, dispel depression, induce sweat and remove dampness. It is contraindicated for those with excessive body weight and excessive fire due to excessive body weight.
Red bean: sweet, sour and flat. Induce diuresis to alleviate edema, detoxify and discharge pus, and descend to dispel blood and induce diuresis, with lower abdomen full.
Orange peel: bitter, pungent and warm. Regulate qi, invigorate spleen, dry dampness and resolve phlegm. For resolving food stagnation and resolving phlegm, heat in chest.
Herba Lycopi: bitter, pungent and slightly warm. Promoting blood circulation to remove blood stasis, and inducing diuresis to alleviate edema. Herba Lycopi is a special herb for treating bleeding into water, and is used for removing blood stasis and edema.
Oriental Waterplantain rhizome: sweet and cold. Has the functions of promoting urination, clearing damp-heat and promoting phlegm retention. Modern pharmacological researches have shown that alisma has the effects of reducing blood fat, resisting fatty liver, dilating coronary artery, reducing blood sugar and the like.
Capillary artemisia: bitter, pungent and slightly cold. Clear damp-heat and relieve jaundice. Long-term taking of the health-care tea can lighten the body, benefit qi and resist aging. Bland in flavor and diuretic in nature, it is a special herb for damp-heat in spleen and stomach. The essential herbs for removing dampness and resolving heat-accumulation are also indicated. Modern pharmacological researches have shown that herba Artemisiae Scopariae has the effects of promoting function of gallbladder, protecting liver, reducing blood lipid, dilating coronary artery, lowering blood pressure, relieving fever, killing ascariasis and resisting dermatophytes.
Poria cocos: sweet, light and flat. Induce diuresis and excrete dampness, invigorate spleen and calm heart. Herbs that promote diuresis and remove dampness.
Cortex Magnoliae officinalis: bitter, pungent and warm. Dry dampness and remove phlegm, and lower qi and remove fullness.
Radish seed: pungent, sweet and flat. Promote digestion and remove distention, reduce qi and resolve phlegm.
Lotus leaf: bitter and flat. Clear summer heat, raise clear yang, cool blood and stop bleeding. Ascending yang qi can dispel blood stasis and keep blood. Modern pharmacological researches have shown that lotus leaf has the effects of dilating blood vessel, relieving spasm, lowering blood pressure and reducing blood lipid.
Motherwort: bitter, pungent and slightly cold. Promoting blood circulation, regulating menstruation, inducing diuresis and relieving swelling. Promoting blood circulation and nourishing blood, promoting blood circulation without damaging new blood, nourishing blood without stagnation of blood stasis, and being a holy medicine for blood families.
Radix astragali: sweet and warm. Tonify qi, strengthen superficies, induce diuresis, remove toxic substances, expel pus, heal wound and promote tissue regeneration. It is indicated for spleen and stomach weakness.
Semen Coicis: sweet, light and cool. Spleen invigorating, dampness eliminating, arthralgia relieving, antidiarrheal, heat clearing and pus discharging. The long-term taking of the medicine can lighten the body and benefit qi. Has effects in benefiting intestines and stomach, and eliminating edema. The coix seed has a wide swelling in water.
Embodiment one:
the invention provides a traditional Chinese medicine composition which can be applied to preparation of lipid-lowering and weight-losing medicines, and is particularly used for treating spleen deficiency, phlegm stasis and damp-heat type obesity, spleen deficiency, phlegm stasis and cold-damp type obesity and spleen deficiency, phlegm stasis and damp-cold-heat type mixed type obesity.
Wherein: the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and damp heat type obesity comprises the following raw materials in parts by weight: 10 parts of corn silk, 10 parts of coix seed, 5 parts of radish seed, 10 parts of hawthorn, 10 parts of poria cocos, 10 parts of lotus leaf, 5 parts of rhizoma alismatis, 10 parts of red bean, 5 parts of vinegar-prepared rhubarb, 10 parts of gynostemma pentaphylla, 5 parts of magnolia officinalis, 5 parts of semen cassiae, 5 parts of herba artemisiae capillaris and 10 parts of motherwort;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold dampness type obesity comprises the following raw materials in parts by weight: 10 parts of corn silk, 10 parts of coix seed, 10 parts of red bean, 5 parts of radish seed, 10 parts of poria cocos, 10 parts of herba lycopi, 5 parts of plantain seed, 10 parts of astragalus membranaceus, 5 parts of bighead atractylodes rhizome, 10 parts of hawthorn, 10 parts of lotus leaf, 5 parts of rhizoma alismatis, 5 parts of orange peel and 3 parts of rhizoma atractylodis;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat mixed type obesity comprises the following raw materials in parts by weight: 10 parts of corn silk, 10 parts of coix seed, 5 parts of radish seed, 10 parts of hawthorn, 10 parts of lotus leaf, 10 parts of poria cocos, 5 parts of rhizoma alismatis, 10 parts of red bean, 5 parts of rheum officinale processed with vinegar, 10 parts of gynostemma pentaphylla, 5 parts of magnolia officinalis, 5 parts of semen cassiae, 5 parts of herba artemisiae capillaris, 10 parts of motherwort herb, 10 parts of herba lycopi, 5 parts of semen plantaginis, 10 parts of astragalus membranaceus, 5 parts of bighead atractylodes rhizome, 5 parts of orange peel and 3 parts of rhizoma atractylodis.
The preparation method of the traditional Chinese medicine composition comprises the following steps: weighing raw materials according to the weight parts, drying the obtained raw materials, uniformly mixing, grinding into powder, sieving with a 50-mesh medicine sieve to obtain medium powder, sterilizing for 8 hours under an ultraviolet sterilizing lamp to obtain an intermediate, and preparing the intermediate into an oral preparation.
Wherein the oral preparation is tablet, dispersant, soft capsule, granule, pill, dripping pill, gel or oral liquid.
Specific: the preparation process of the tablets in the oral preparation is as follows: selecting an intermediate, adding gypsum powder, common auxiliary materials and an adhesive, mixing, granulating, drying, adding a lubricant, uniformly mixing, granulating, and tabletting to obtain tablets; the common auxiliary materials are one or more than two of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; the adhesive is one of distilled water or 30% ethanol solution; the lubricant is one of 0.1% magnesium stearate, 0.1% talcum powder or 0.1% micropowder silica gel.
The preparation process of the soft capsule in the oral preparation comprises the following steps: selecting an intermediate, adding 1% of polyethylene glycols, a plasticizer, a disintegrating agent, curcumin, ferric oxide, a wetting agent and a suspending agent, uniformly mixing, and filling into a soft capsule; the plasticizer is one of glycerol or polyalcohol; the disintegrating agent is selected from one of dry starch or effervescent disintegrating agent; the wetting agent is one of 30% ethanol or liquid paraffin; the suspending agent is one of beeswax, aluminum monostearate or ethyl cellulose.
Embodiment two:
the invention provides a traditional Chinese medicine composition which can be applied to preparation of lipid-lowering and weight-losing medicines, and is particularly used for treating spleen deficiency, phlegm stasis and damp-heat type obesity, spleen deficiency, phlegm stasis and cold-damp type obesity and spleen deficiency, phlegm stasis and damp-cold-heat type mixed type obesity.
Wherein: the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and damp heat type obesity comprises the following raw materials in parts by weight: 60 parts of corn silk, 60 parts of coix seed, 30 parts of radish seed, 60 parts of hawthorn, 50 parts of poria cocos, 60 parts of lotus leaf, 50 parts of rhizoma alismatis, 60 parts of red bean, 30 parts of vinegar-processed rheum officinale, 30 parts of gynostemma pentaphylla, 30 parts of magnolia officinalis, 30 parts of semen cassiae, 30 parts of herba artemisiae capillaris and 60 parts of motherwort;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold dampness type obesity comprises the following raw materials in parts by weight: 60 parts of corn silk, 60 parts of coix seed, 60 parts of red bean, 30 parts of radish seed, 50 parts of poria cocos, 50 parts of herba lycopi, 50 parts of plantain seed, 50 parts of astragalus mongholicus, 30 parts of bighead atractylodes rhizome, 60 parts of hawthorn, 60 parts of lotus leaf, 50 parts of rhizoma alismatis, 30 parts of orange peel and 30 parts of rhizoma atractylodis;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat mixed type obesity comprises the following raw materials in parts by weight: 60 parts of corn silk, 60 parts of coix seed, 30 parts of radish seed, 60 parts of hawthorn, 60 parts of lotus leaf, 50 parts of poria cocos, 50 parts of rhizoma alismatis, 60 parts of red bean, 30 parts of vinegar-processed rheum officinale, 30 parts of gynostemma pentaphylla, 30 parts of magnolia officinalis, 30 parts of semen cassiae, 30 parts of herba artemisiae capillaris, 60 parts of motherwort, 50 parts of herba lycopi, 50 parts of semen plantaginis, 50 parts of astragalus membranaceus, 30 parts of bighead atractylodes rhizome, 30 parts of orange peel and 30 parts of rhizoma atractylodis.
The preparation method of the traditional Chinese medicine composition comprises the following steps: weighing raw materials according to the weight parts, drying the obtained raw materials, uniformly mixing, grinding into powder, sieving with a 100-mesh medicine sieve to obtain medium powder, sterilizing for 8 hours under an ultraviolet sterilizing lamp to obtain an intermediate, and preparing the intermediate into an oral preparation.
Wherein the oral preparation is tablet, dispersant, soft capsule, granule, pill, dripping pill, gel or oral liquid.
Specific: the preparation process of the tablets in the oral preparation is as follows: selecting an intermediate, adding gypsum powder, common auxiliary materials and an adhesive, mixing, granulating, drying, adding a lubricant, uniformly mixing, granulating, and tabletting to obtain tablets; the common auxiliary materials are one or more than two of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; the adhesive is one of distilled water or 70% ethanol solution; the lubricant is one of 1% magnesium stearate, 3% talcum powder or 0.3% micro silica gel.
The preparation process of the soft capsule in the oral preparation comprises the following steps: selecting an intermediate, adding 15% of polyethylene glycols, a plasticizer, a disintegrating agent, curcumin, ferric oxide, a wetting agent and a suspending agent, uniformly mixing, and filling into a soft capsule; the plasticizer is one of glycerol or polyalcohol; the disintegrating agent is selected from one of dry starch or effervescent disintegrating agent; the wetting agent is one of 70% ethanol or liquid paraffin; the suspending agent is one of beeswax, aluminum monostearate or ethyl cellulose.
Embodiment III:
the invention provides a traditional Chinese medicine composition which can be applied to preparation of lipid-lowering and weight-losing medicines, and is particularly used for treating spleen deficiency, phlegm stasis and damp-heat type obesity, spleen deficiency, phlegm stasis and cold-damp type obesity and spleen deficiency, phlegm stasis and damp-cold-heat type mixed type obesity.
Wherein: the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and damp heat type obesity comprises the following raw materials in parts by weight: 35 parts of corn silk, 35 parts of coix seed, 18 parts of radish seed, 35 parts of hawthorn, 30 parts of poria cocos, 35 parts of lotus leaf, 18 parts of rhizoma alismatis, 35 parts of red bean, 18 parts of rheum officinale processed with vinegar, 20 parts of gynostemma pentaphylla, 18 parts of magnolia officinalis, 18 parts of semen cassiae, 18 parts of herba artemisiae capillaris and 35 parts of herba leonuri;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold dampness type obesity comprises the following raw materials in parts by weight: 35 parts of corn silk, 35 parts of coix seed, 35 parts of red bean, 18 parts of radish seed, 30 parts of poria cocos, 30 parts of herba lycopi, 18 parts of plantain seed, 30 parts of astragalus membranaceus, 18 parts of bighead atractylodes rhizome, 35 parts of hawthorn, 35 parts of lotus leaf, 28 parts of rhizoma alismatis, 18 parts of orange peel and 17 parts of rhizoma atractylodis;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat mixed type obesity comprises the following raw materials in parts by weight: 35 parts of corn silk, 35 parts of coix seed, 18 parts of radish seed, 35 parts of hawthorn, 35 parts of lotus leaf, 30 parts of poria cocos, 28 parts of rhizoma alismatis, 35 parts of red bean, 18 parts of rheum officinale processed with vinegar, 20 parts of gynostemma pentaphylla, 18 parts of magnolia officinalis, 18 parts of semen cassiae, 18 parts of herba artemisiae capillaris, 35 parts of motherwort, 28 parts of herba lycopi, 18 parts of semen plantaginis, 30 parts of astragalus membranaceus, 18 parts of bighead atractylodes rhizome, 18 parts of orange peel and 17 parts of rhizoma atractylodis.
The preparation method of the traditional Chinese medicine composition comprises the following steps: weighing raw materials according to the weight parts, drying the obtained raw materials, uniformly mixing, grinding into powder, sieving with a 75-mesh medicine sieve to obtain medium powder, sterilizing for 8 hours under an ultraviolet sterilizing lamp to obtain an intermediate, and preparing the intermediate into an oral preparation.
Wherein the oral preparation is tablet, dispersant, soft capsule, granule, pill, dripping pill, gel or oral liquid.
Specific: the preparation process of the tablets in the oral preparation is as follows: selecting an intermediate, adding gypsum powder, common auxiliary materials and an adhesive, mixing, granulating, drying, adding a lubricant, uniformly mixing, granulating, and tabletting to obtain tablets; the common auxiliary materials are one or more than two of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; the adhesive is one of distilled water or 50% ethanol solution; the lubricant is one of 0.5% magnesium stearate, 1.5% talcum powder or 0.2% micropowder silica gel.
The preparation process of the soft capsule in the oral preparation comprises the following steps: selecting an intermediate, adding 8% of polyethylene glycols, a plasticizer, a disintegrating agent, curcumin, ferric oxide, a wetting agent and a suspending agent, uniformly mixing, and filling into a soft capsule; the plasticizer is one of glycerol or polyalcohol; the disintegrating agent is selected from one of dry starch or effervescent disintegrating agent; the wetting agent is one of 50% ethanol or liquid paraffin; the suspending agent is one of beeswax, aluminum monostearate or ethyl cellulose.
On the basis of ensuring the treatment effect of the original traditional Chinese medicine, the preparation method of the tablet and the soft capsule is adopted for the convenience of storage, carrying and taking of patients, so that the traditional Chinese medicine can be directly taken, is safe and sanitary, is convenient to carry and store, is easy to produce and sell, and changes the situation of complicated taking method of the traditional Chinese medicine preparation. The traditional Chinese medicine composition provided by the invention has reasonable compatibility, is compatible with the pathogenesis, combines five causes and pathogenesis of obesity with different attributes of cold and heat, and is a unique special prescription for treating the disease; the traditional Chinese medicine composition for treating spleen deficiency, phlegm stagnation and damp-heat type has the effects of clearing heat, removing dampness, activating blood, removing stasis, strengthening spleen, eliminating turbidity, reducing fat and losing weight; the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and cold dampness has the effects of strengthening spleen, eliminating dampness, activating blood, dissolving stasis, dispelling cold, eliminating turbid pathogen, reducing lipid and losing weight; the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat staggering has the effects of strengthening spleen, resolving dampness, activating blood, removing stasis, dispelling cold, clearing heat, resolving turbidity, eliminating phlegm and losing weight; the invention adopts the raw materials with homology of medicine and food, has no side effect and has obvious curative effect on obesity. Aiming at other weight-losing medicines, the scheme of the invention has the characteristics of fitting the pathogenesis, distinguishing the body for treatment, addressing both the symptoms and root causes, simple typing, innovation and practicality, no rebound, convenient popularization and suitability for children obesity.
The traditional Chinese medicine composition disclosed by the invention is subjected to clinical curative effect tracking, and the treatment process and the treatment result are as follows:
1. selecting a patient:
3600 obese patients were selected, randomized into treatment and time-dependent groups. After entering the treatment group, differentiation and typing are carried out according to clinical manifestations, wherein the three types are divided into 600 cases of spleen deficiency phlegm stasis damp heat type (namely positive composite physique type), 600 cases of spleen deficiency phlegm stasis cold dampness type (namely negative composite physique type), 600 cases of spleen deficiency phlegm stasis damp turbidity cold heat type (namely mixed physique type), and the corresponding traditional Chinese medicine composition is adopted for treatment.
Control group: the rest 1800 cases are treated with the following 4 control medicines, wherein 600 cases are the lipid-lowering and weight-losing tablets, 600 cases are the toxin-expelling and lipid-clearing capsules, and 600 cases are the weight-losing and fat-losing pills.
That is, the control group of each medicine corresponds to the three types of treatment groups, and the number of people in the control group is the same as that in the treatment groups.
2. Standard of efficacy: according to the criterion of the treatment effect of obesity in the ministry of health, the clinical study guidelines for treating obesity by using new traditional Chinese medicines, the method is divided into clinical control, obvious effect, effective and ineffective.
3. Treatment course: three months is a course of treatment.
4. The treatment effect is as follows: and observing the result of one treatment course, and unifying the results into the total effective rate according to the effective and the effective results.
5. Treatment and control efficacy comparisons:
(1) Compared with the lipid-lowering and weight-losing tablet of the control group, the spleen deficiency, phlegm stasis, turbid heat and dampness-removing tablet has the efficacy
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 131 17 2 0 100%
Control group 10 19 70 51 66%
Statistically processed p < 0.01
(2) Compared with the lipid-lowering and weight-losing tablet of the control group, the spleen deficiency, phlegm stasis, turbid cold dampness type
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 120 21 9 0 100%
Control group 5 13 4 89 40.67%
Statistically processed p < 0.01
(3) Compared with the lipid-lowering and weight-losing tablet of the control group, the efficacy of the lipid-lowering and weight-losing tablet of spleen deficiency, phlegm stasis, damp turbidity, cold and heat mixed type
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 115 24 11 0 100%
Control group 7 39 42 62 58.67%
Statistically processed p < 0.01
(4) Compared with the weight-losing tablet of the control group, the spleen deficiency phlegm stasis turbid damp heat type has the effect of reducing weight
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 130 17 3 0 100%
Control group 20 25 55 50 66.7%
Statistically processed p < 0.01
(5) Compared with the weight-losing tablet of the control group, the weight-losing tablet of the spleen deficiency, phlegm stasis, turbid cold dampness
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 121 17 3 0 100%
Control group 5 10 41 94 37.3%
Statistically processed p < 0.01
(6) Compared with the weight-losing tablet of the control group, the efficacy of the weight-losing tablet of spleen deficiency, phlegm stasis, damp turbidity, cold and heat
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 116 24 10 10 100%
Control group 7 40 43 60 60%
Statistically processed p < 0.01
(7) Compared with the efficacy of the capsule for expelling toxin and clearing fat of the control group
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 132 17 1 0 100%
Control group 15 20 60 55 63.3%
Statistically processed p < 0.01
(8) Compared with the efficacy of the toxin-expelling and lipid-clearing capsule of the control group, the efficacy of the toxin-expelling and lipid-clearing capsule of the spleen deficiency, phlegm stasis, turbid cold dampness
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 121 20 9 0 100%
Control group 1 10 40 99 34%
Statistically processed p < 0.01
(9) Compared with the treatment effect of the toxin expelling and fat clearing capsule of the control group, the capsule has the effects of spleen deficiency, phlegm stasis, turbid dampness, cold and heat and impurity removal
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 117 23 10 0 100%
Control group 5 25 30 90 40%
Statistically processed p < 0.01
(10) Compared with the control group pill for reducing weight and eliminating fat in spleen deficiency, phlegm stasis, turbid damp-heat type
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 130 18 2 0 100%
Control group 25 25 50 50 66.7%
Statistically processed p < 0.01
(11) Compared with the control group, the pill has the effect of reducing weight and eliminating fat
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 120 20 10 0 100%
Control group 6 21 18 105 30%
Statistically processed p < 0.01
(12) Compared with the control group weight-reducing and fat-eliminating pill, the spleen deficiency, phlegm stasis, turbid dampness, cold and heat mixed type pill has the curative effect
Control group Clinical control Has obvious effect Effective and effective Invalidation of Total effective rate
Treatment group 116 25 9 0 100%
Control group 10 28 42 70 53.35
Statistically processed p < 0.01
6. Continuation of treatment results after control group treatment was not effective:
a total of 875 patients after a single treatment session in the control group failed to follow the full-improvement treatment group regimen. After a course of treatment (3 months), the result is: 525 cases of clinical control (60 percent), 210 cases of obvious effect dipping of 24 percent), 140 cases of effective control (16 percent), 0 cases of ineffective control and 100 percent of total effective rate.
Application example 1.
Wei X, male, 35 years old, employee. The patient has a history of obesity for 5 years, plain smoking and drinking, and almost every day for night. In the next two months, the patient feels abdominal distention, bitter and dry, and the stool is sticky and smelly, and can visit the doctor at home once to twice a day. The body height is 172 cm, the body weight is 82 kg, the abdomen is distended, the touch is hard, the tongue is light red, and the coating is light yellow, thick and greasy. The spleen deficiency, phlegm stasis, turbid damp-heat type traditional Chinese medicine composition is given after 2 weeks for rechecking, abdominal distention is obviously improved, and body weight is reduced to 75 kg. After two months the body weight was reduced to 67 kg and the symptoms disappeared.
Application example 2.
Cinnabar XX, female, 25 years old, after graduate in university. Western medicines are taken for anxiety disorder (specific medicines are not detailed) before two years, obesity starts to appear, and the weight is still increased after stopping taking medicines, so that patients visit a doctor in the stop, have the height of 162 cm, the weight of 70 cm, debilitation, no mouth dryness and bitter taste, sometimes sticky stool, pale red tongue, tooth marks on the side, white tongue coating, and syndrome differentiation of mixed composite physique obesity, and the spleen deficiency, phlegm stasis, damp turbidity, cold and heat mixed traditional Chinese medicine composition is given, and the weight is reduced to 56 ℃ after two half months. All syndromes disappear.
Application example 3.
Horse X, men, 38 years old, staff. The patient is obese for three years, has large abdomen and face, debilitation, loose stool, 3 to 4 times per day, the height is 171 cm, the weight is 73 kg, the head is dizziness and sleepiness, the tongue is light red, and the tongue coating is watery. Obesity is caused by syndrome differentiation belonging to negative complex constitution. The traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold dampness is administered. After two weeks, the symptoms are repeated, the weakness is eliminated, the stool is normal, the abdomen and the face are obviously improved, and the weight is reduced to 65 kg.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (8)

1. A traditional Chinese medicine composition for reducing blood fat and losing weight is characterized by being used for treating spleen deficiency, phlegm stasis, damp heat type obesity, spleen deficiency, phlegm stasis, cold dampness type obesity and spleen deficiency, phlegm stasis, damp turbidity, cold heat type mixed type obesity;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid damp and heat comprises raw materials including corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, rhizoma alismatis and red bean, vinegar-processed rheum officinale, gynostemma pentaphylla, magnolia officinalis, semen cassiae, herba artemisiae capillaris and herba leonuri;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis and cold dampness comprises raw materials including corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, rhizoma alismatis and red bean, herba lycopi, semen plantaginis, astragalus membranaceus, bighead atractylodes rhizome, orange peel and rhizoma atractylodis;
the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat and impurity symptoms comprises corn silk, coix seed, radish seed, hawthorn, lotus leaf, poria cocos, rhizoma alismatis and red bean, vinegar processed rheum officinale, gynostemma pentaphylla, magnolia officinalis, semen cassiae, herba artemisiae capillaries, herba leonuri, herba lycopi, semen plantaginis, astragalus membranaceus, bighead atractylodes rhizome, orange peel and rhizoma atractylodis.
2. The traditional Chinese medicine composition for reducing blood fat and losing weight according to claim 1, which is characterized in that: the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid damp and hot type obesity comprises the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-50 parts of poria cocos, 10-60 parts of lotus leaf, 5-50 parts of rhizoma alismatis, 10-60 parts of red bean, 5-30 parts of vinegar-processed rheum officinale, 10-30 parts of gynostemma pentaphylla, 5-30 parts of magnolia officinalis, 5-30 parts of semen cassiae, 5-30 parts of herba artemisiae capillaris and 10-60 parts of motherwort.
3. The traditional Chinese medicine composition for reducing blood fat and losing weight according to claim 1, which is characterized in that: the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, turbid cold dampness type obesity comprises the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 10-60 parts of red bean, 5-30 parts of radish seed, 10-50 parts of poria cocos, 10-50 parts of herba lycopi, 5-50 parts of semen plantaginis, 10-50 parts of astragalus membranaceus, 5-30 parts of bighead atractylodes rhizome, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 5-50 parts of rhizoma alismatis, 5-30 parts of orange peel and 3-30 parts of rhizoma atractylodis.
4. The traditional Chinese medicine composition for reducing blood fat and losing weight according to claim 1, which is characterized in that: the traditional Chinese medicine composition for treating spleen deficiency, phlegm stasis, damp turbidity, cold and heat mixed type obesity comprises the following raw materials in parts by weight: 10-60 parts of corn silk, 10-60 parts of coix seed, 5-30 parts of radish seed, 10-60 parts of hawthorn, 10-60 parts of lotus leaf, 10-50 parts of poria cocos, 5-50 parts of rhizoma alismatis, 10-60 parts of red bean, 5-30 parts of vinegar processed rheum officinale, 10-30 parts of gynostemma pentaphylla, 5-30 parts of magnolia officinalis, 5-30 parts of semen cassiae, 5-30 parts of herba artemisiae capillaris, 10-60 parts of leonurus, 10-50 parts of herba lycopi, 5-50 parts of semen plantaginis, 10-50 parts of astragalus membranaceus, 5-30 parts of bighead atractylodes rhizome, 5-30 parts of orange peel and 3-30 parts of rhizoma atractylodis.
5. The traditional Chinese medicine composition for reducing blood fat and losing weight according to any one of claims 1 to 4, further comprising a preparation method of the traditional Chinese medicine composition for reducing blood fat and losing weight, and is characterized by comprising the following steps:
weighing raw materials according to the weight parts, drying the obtained raw materials, uniformly mixing, grinding into powder, sieving with a 50-100 mesh medicine sieve to obtain medium powder, sterilizing for 8 hours under an ultraviolet sterilizing lamp to obtain an intermediate, and preparing the intermediate into an oral preparation.
6. The method for preparing the traditional Chinese medicine composition for reducing blood fat and losing weight according to claim 5, which is characterized in that: the oral preparation is tablet, dispersant, soft capsule, granule, pill, dripping pill, gel or oral liquid.
7. The method for preparing the lipid-lowering and weight-losing traditional Chinese medicine composition according to claim 6, wherein the preparation process of the tablets in the oral preparation is as follows: selecting an intermediate, adding gypsum powder, common auxiliary materials and an adhesive, mixing, granulating, drying, adding a lubricant, uniformly mixing, granulating, and tabletting to obtain tablets; the common auxiliary materials are one or more than two of starch, powdered sugar, microcrystalline cellulose, inorganic salts and mannitol; the adhesive is one of distilled water or 30% -70% ethanol solution; the lubricant is one of magnesium stearate 0.1-1%, talcum powder 0.1-3% or micro silica gel 0.1-0.3%.
8. The method for preparing the traditional Chinese medicine composition for reducing blood fat and losing weight according to claim 6, wherein the preparation process of the soft capsule in the oral preparation is as follows: selecting an intermediate, adding 1% -15% of polyethylene glycols, a plasticizer, a disintegrating agent, curcumin, ferric oxide, a wetting agent and a suspending agent, uniformly mixing, and filling into a soft capsule; the plasticizer is one of glycerol or polyalcohol; the disintegrating agent is one of dry starch or effervescent disintegrating agent; the wetting agent is one of 30% -70% ethanol or liquid paraffin; the suspending agent is one of beeswax, aluminum monostearate or ethyl cellulose.
CN202310881638.XA 2023-07-18 2023-07-18 Traditional Chinese medicine composition for reducing blood fat and losing weight and preparation method thereof Pending CN116726115A (en)

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