CN102416117A - Chinese patent medicine for treating psoriasis - Google Patents
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Abstract
The invention discloses a Chinese patent medicine for treating psoriasis, and belongs to the technical field of treatment medicines for psoriasis. In the technical scheme, the Chinese patent medicine for treating psoriasis is characterized by being prepared from the following medicaments: lightyellow sophora root, phellodendron, coix seed, densefruit pittany root-bark, rehmannia root, red paeony root, great burdock achene, belvedere fruit, common ducksmeat herb, talcpowder, cortex moutan, stiff silkworm, honeysuckle flower, fineleaf schizonepeta herb, common anemarrhena rhizome, white paeony root, dwarf lilyturf tuber, donkey-hide gelatin, adenophora, divaricate saposhnikovia root, papaya, clematis root, baical skullcap root, raw polygonum multiflorum thunb and liquoric root. Compared with the prior art, the invention has the obvious substantial characteristic and advantage that the Chinese patent medicine can eliminate diseases of patients and promote physical and psychological health, is low in treatment cost, convenient to take by the patients and quick in curative effect, does not have side effect and is used for treating psoriasis.
Description
Technical field
The present invention relates to psoriatic treatment technology field, relate in particular to a kind of technical field of treating psoriatic Chinese patent medicine.
Background technology
Psoriasis is a kind of common chronic dermatosis, and it mainly is on erythema, to occur the silvery white dry squama of multilamellar repeatedly.Traditional Chinese medical science Gu is referred to as “ Bai Mange ", ancient doctor's nationality also is referred to as psoriasis.Doctor trained in Western medicine is called psoriasis (Psoriasis), is commonly called as psoriasis, the pimple that it occurs differing in size, and erythema, surface coverage silvery white squama, clear border, the male is more than the women.The psoriasis easy relapse, winter in spring easy relapse or increase the weight of, and alleviate summer and autumn more.The position of morbidity is the most common with scalp, is shank, ancon, back, upper arm, forearm, knee, chest and abdominal part and buttocks etc. secondly.Often be symmetry and distribute, also can distribute along tegumentary nerve is the wire arrangement.
The patient is owing to scratch, near affected part and can also can have new flat hillock rash to occur it with scratch, petechia or blood crusts on every side; Conscious paroxysmal is very itched, and is more acute during by clothing friction and sweat stain, becoming severe at night, and that scratches does not know pain.During anxious state of mind, pruritus is aggravation thereupon also.Because of pruritus can influence work and rest, the patient often with insomnia, dizzy, irritated symptom, because of this disease course of disease is slow, do not heal by constant year, and outbreak often brings great body and mind misery and financial burden to the patient repeatedly.Because of the obstinate refractory of this disease, still classified as the important subject in department of dermatologry field, the world today, be one of whole world department of dermatologry keypoint control disease.In the psoriasis control; The traditional Chinese medical science, doctor trained in Western medicine and the combination of Chinese and Western medicine all have many patent medicine and successful Therapeutic Method, but have also brought many troubles to the patient, like having made of doctor trained in Western medicine anticarcinogen and hormone medicine; Its serious adverse has been brought more serious wrecking to patient's body; Its weak curative effect, outbreak makes the patient dissatisfied repeatedly, has not only brought many miseries to the patient, and has brought the medical expense of great number.Therefore, seek a kind of illness new, that can eliminate the patient, have take medicine conveniently, curative effect is fast, being used to of having no side effect treat the problem that technical staff that psoriatic Chinese patent medicine is still the present technique field needs to be resolved hurrily.
Summary of the invention:
Technical problem to be solved by this invention is the deficiency that overcomes prior art, and provides a kind of to eliminate patient's illness, promote physically and mentally healthy, the psoriatic Chinese patent medicine of treatment that have simultaneously that medical expense is low, the patient takes medicine conveniently, curative effect is fast, has no side effect.
For solving the problems of the technologies described above; The present invention adopts following technical scheme: the psoriatic Chinese patent medicine of a kind of treatment, its special character is to be prepared from following medicaments in part by weight: Radix Sophorae Flavescentis 10-30 part, Cortex Phellodendri 10-30 part, Semen Coicis 20-50 part, favus skin 20-50 part, Radix Rehmanniae 30-60 part, Radix Paeoniae Rubra 10-30 part, Fructus Arctii 10-30 part, Fructus Kochiae 10-30 part, Herba Spirodelae 10-30 part, Pulvis Talci 20-50 part, Cortex Moutan 10-30 part, Bombyx Batryticatus 10-30 part, Flos Lonicerae 30-60 part, Herba Schizonepetae 10-30 part, Rhizoma Anemarrhenae 10-30 part, Radix Paeoniae Alba 20-50 part, Radix Ophiopogonis 20-50 part, Colla Corii Asini 20-50 part, Radix Adenophorae (Radix Glehniae) 20-50 part, windproof 10-30 part, Fructus Chaenomelis 10-30 part, Radix Clematidis 10-30 part, Radix Scutellariae 10-30 part, Radix Polygoni Multiflori 30-60 part, Radix Glycyrrhizae 20-50 part.
For further solving the problems of the technologies described above, the preferred version of said medicine weight portion is: Radix Sophorae Flavescentis 15-25 part, Cortex Phellodendri 15-25 part, Semen Coicis 30-40 part, favus skin 30-40 part, Radix Rehmanniae 40-50 part, Radix Paeoniae Rubra 15-25 part, Fructus Arctii 15-25 part, Fructus Kochiae 15-25 part, Herba Spirodelae 15-25 part, Pulvis Talci 30-40 part, Cortex Moutan 15-25 part, Bombyx Batryticatus 15-25 part, Flos Lonicerae 40-50 part, Herba Schizonepetae 15-25 part, Rhizoma Anemarrhenae 15-25 part, Radix Paeoniae Alba 30-40 part, Radix Ophiopogonis 30-40 part, Colla Corii Asini 30-40 part, Radix Adenophorae (Radix Glehniae) 30-40 part, windproof 15-25 part, Fructus Chaenomelis 15-25 part, Radix Clematidis 15-25 part, Radix Scutellariae 15-25 part, Radix Polygoni Multiflori 40-50 part, Radix Glycyrrhizae 30-40 part.
For further solving the problems of the technologies described above, the preferred plan of said medicine weight portion is: 20 parts of Radix Sophorae Flavescentiss, 20 parts of Cortex Phellodendris, 35 parts of Semen Coicis, 35 parts of favus skins, 45 parts in the Radix Rehmanniae, 20 parts of Radix Paeoniae Rubra, 20 parts of Fructus Arctiis, 20 parts of the Fructus Kochiae, 20 parts in Herba Spirodelae, 35 parts of Pulvis Talci, 20 parts of Cortex Moutans, 20 parts of Bombyx Batryticatus, 45 parts of Flos Loniceraes, 20 parts of Herba Schizonepetae, 20 parts of the Rhizoma Anemarrhenaes, 35 parts of the Radix Paeoniae Albas, 35 parts of Radix Ophiopogonis, 35 parts in Colla Corii Asini, 35 parts of Radix Adenophorae (Radix Glehniae), windproof 20 parts, 20 parts of Fructus Chaenomeliss, 20 parts of Radix Clematidis, 20 parts of Radix Scutellariaes, 45 parts of Radix Polygoni Multifloris, 35 parts in Radix Glycyrrhizae.
Above-mentioned described Chinese patent medicine is processed the oral medicine dosage form of pill, sublimed preparation, powder, tablet, unguentum, decoction and capsule dress powder according to the conventional technology of preparing of Chinese medicine.
Above-mentioned described Chinese patent medicine also contains drug excipient.
Above-mentioned described Chinese patent medicine is used for the application as treatment psoriasis disease.
The principles of formulating prescriptions of Chinese patent medicine of the present invention are: regulating the blood flow circulation, painful antipruritic, the cooling blood and dissolving purpura of clearing away heart-fire, expelling wind and removing dampness, kidney tonifying detoxifcation, town, enhancement telangiectasis improve immune function of human body, thereby reach the psoriatic purpose of treatment.The present invention has proper, the reasonable recipe of compatibility of drugs, and the effect of its said each herbal medicine is:
Radix Sophorae Flavescentis: another name: wild Chinese scholartree, brave man's branch, bitter bone, bone, Chinese scholartree, Albizzia kalkora; Cold in nature, bitter in the mouth, GUIXIN, liver, stomach, large intestine, urinary bladder channel; Effect: heat clearing and damp drying, parasite killing, diuresis.Cure mainly: be used for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Cortex Phellodendri: bitter in the mouth, cold in nature, have the effect of heat-clearing and toxic substances removing, heat clearing and damp drying, cure mainly: hygropyretic dysentery, have loose bowels, jaundice; Nocturnal emission, stranguria with turbid discharge, leukorrhagia; The hectic fever due to YIN-deficiency consumptive fever; And aphtha of the mouth and tongue; Conjunctival congestion and swelling pain; Skin sore; Skin eczema.Cortex Phellodendri and Rhizoma Coptidis contain more berberine equally, thus also broadly similar of its pharmacological action, referring to the Rhizoma Coptidis bar.But content is low than Rhizoma Coptidis, and contains other compositions, and effect is some difference also.
Semen Coicis is the Chinese medicine of using always. being the food of generally often eating, the property slightly sweet flavor, being slightly cold that effects such as inducing diuresis to remove edema, spleen invigorating are dried, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus are arranged again, is damp-clearing drug commonly used.Main component is that protein, vitamin B1, B2 make skin smooth, reduces wrinkle, eliminates the effect of pigment spot.The moist skin that Semen Coicis itself the had effects such as mending wet promoting flow of QI and blood menstruction regulating and pain relieving of whitening very distinguishedly is applied to have again on the skin natural beauty white effect and can improves skin metabolism and moisture preserving function.
Cortex Dictamni: cold in nature, bitter in the mouth, return spleen, stomach, bladder, small intestine meridian; Effect is a heat clearing and damp drying, dispels the wind detoxifcation; The clinical damp and hot sore, pus all over nest, yellow fluid of being used for is dripping; And skin pruritus, skin ulcer tinea mange, pudendum disease, Cortex Dictamni such as swell and ache is to dispel the wind, remove damp and hot medicine; And but eliminating dampness by diuresis heat is applicable to diseases such as skin ulcer tinea pruritus due to damp pathogen in lower orifices, often cooperates medicines such as Radix Sophorae Flavescentis, the Fructus Kochiae with using; Both oral administration also can be fried in shallow oil the soup washout.
The Radix Rehmanniae: Radix Rehmanniae sweet in the mouth, hardship, cold in nature.GUIXIN, liver, lung meridian.Function cures mainly: has the clearing away heat and cooling blood effect, is used for the warm febrile disease blood of joining the army, and the high fever coma, dry tongue is deep red; Control the epidemic febrile disease later stage, waste heat to the greatest extent, do not hinder, night fever abating at dawn, red tongue rapid pulse person by cloudy liquid; Can be used for controlling the warm febrile disease blood of joining the army, the heat in blood poison is contained, hematemesis and epistaxis, and macule is purple black; The YIN nourishing and the production of body fluid promoting effect.It is thirsty also to can be used for Tianjin wound, and interior-heat is quenched one's thirst, and controls the epidemic febrile disease impairment of YIN, the dryness of the intestine constipation.
Radix Paeoniae Rubra: sour in the mouth, hardship, cool in nature.Go into liver, spleen channel.Effect: clots absorbing, pain relieving, removing heat from blood, detumescence.Cure mainly: control the stagnant amenorrhea of the stasis of blood, the hernia abdominal mass is gathered, stomachache, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle.
Fructus Arctii: remove impurity, cleaning, drying.Acrid in the mouth, hardship, cold in nature, attach to the lung and stomach meridians, function cures mainly: dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.Be used for anemopyretic cold, cough with copious phlegm, measles, rubella, laryngopharynx swelling and pain, mumps erysipelas, carbuncle sore tumefacting virus.
The Fructus Kochiae: sweet-bitter flavor, cold in nature has the effect of clearing away damp-heat, diuresis; Be used to treat diseases such as skin eczema, dribbling urination, beriberi edema.
Herba Spirodelae: acrid in the mouth, cold in nature.Nontoxic.Go into lung, liver, spleen channel.Effect: diaphoresis, dispel the wind row water, heat clearing away, detoxifcation.Cure mainly: the hot carbuncle of row when controlling, macule is not passed through, wind heat pain rash, skin pruritus, edema, amenorrhea, the skin ulcer tinea, erysipelas is scalded.
Pulvis Talci: be silicates mineral calculi dissolving ground product, sweet in the mouth, light, cold in nature, nontoxic, cure mainly: damp-heat in the urinary bladder, the summer-heat excessive thirst, dysuria is had loose bowels, and urine drenches puckery pain, eczema, eczema, edema, epistaxis, beriberi, diseases such as Skin wet and rotten.
Cortex Moutan: bitter in the mouth, cool in nature, be slightly cold.GUIXIN, liver, kidney, lung meridian.Effect cures mainly: clearing away heat and cooling blood; Promoting blood circulation to remove blood stasis.The epidemic febrile disease pathogenic heat attacking blood system in febrile diseases; Send out speckle; Tell nosebleed; The calentura later stage, hot Fu Yin divided heating; Deficiency of YIN osteopyrexia and fever; Amenorrhea due to stagnation of blood; Dysmenorrhea; Carbuncle sore tumefacting virus; Fall and pounce on the pain of injury; The rheumatism pyretic arthralgia.
Bombyx Batryticatus: acrid in the mouth, salty, property is flat, has expelling wind to relieve convulsion, dissipating phlegm and resolving masses, the effect of heat-clearing and toxic substances removing dampness clinically is used to control heat syndrome cough more, and phlegm dyspnea is spitted blood, collapses, band, traumatic injury, rheumatalgia, sore etc., its range of application and field constantly enlarge in recent years.
Flos Lonicerae: another name: Flos Lonicerae, little egret flower, Flos Lonicerae, Flos Lonicerae, Flos Lonicerae, golden rattan, two bud flower, JINHUA, two precious flowers; Cold in nature, sweet in the mouth; Gui Jing: lung; Stomach is through effect: heat-clearing and toxic substances removing cures mainly: the epidemic febrile disease heating; Toxic-heat and blood stasis; The carbuncle furuncle; Sore throat and multiple infectious disease.
Herba Schizonepetae: acrid in the mouth, slightly warm in nature, return lung, Liver Channel, have the diffusing wind that induces sweat, rash, the skin ulcer that disappears, hemostatic effect, be usually used in treatment flu, measles pass through send out smooth, have blood in stool, diseases such as metrorrhagia, epistaxis.
The Rhizoma Anemarrhenae: remove impurity, clean, run through, cut sheet, drying, QUMAO bits.Bitter in the mouth, sweet, cold in nature, return lung, stomach, kidney channel; Its effect is: clearing away heat-fire, promote the production of body fluid and moisturize.Be used for fever caused by exogenous pathogenic factors, the hyperpyrexia excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, the dryness of the intestine constipation.
The root of herbaceous peony: cold nature, sweet-bitter flavor, function is transferred the obstruction of the liver and ying blood, cures mainly diseases such as abdominal pain due to deficiency of blood, association's pain, dysentery, irregular menstruation, uterine bleeding.
Radix Ophiopogonis: sweet, the little hardship of nature and flavor, be slightly cold.GUIXIN, lung, stomach warp.Function with cure mainly: YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.Be used for dryness of the lung dry cough, the chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.Few thirsty, the dry cough spitting of blood in Tianjin that is used for lung-stomach yin deficiency; Cards such as the palpitation and being susceptible to fright of insufficiency of heart-YIN and calentura later stage consumption of body fluid by heat.
Colla Corii Asini: sweet in the mouth, property is flat, has and enriches blood, and the antiabortive effect of lung is grown in hemostasis, cures mainly sallow, dizzy, the cardiopalmus of blood deficiency; Pulmonary tuberculosis spitting of blood, haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, vaginal bleeding during pregnancy.
Radix Adenophorae (Radix Glehniae): property is sweet, flavor is cool, has clearing away heat and nourishing YIN, and the effect of nourishing the lung to arrest cough cures mainly tracheitis, pertussis, and the cough due to lung-heat, it is yellow thick to cough up phlegm.
Windproof: as acrid in the mouth, sweet, slightly warm in nature, to return bladder, liver, spleen channel, have the effect of expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion, be used to treat diseases such as diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus.
Fructus Chaenomelis: property is flat, temperature, sweet in the mouth, acid, has suppressing the hyperactive liver and easing the stomach, the Shujin network; The muscles and bones of living, the effect of blood pressure lowering, clearing away heart-fire and moistening the lung, the strengthening the spleen that is good for the stomach, be used for women's lactogenic; Lung moistening is good for the stomach, strengthening the spleen to promote digestion, strengthening the spleen to promote digestion, extra-nutrition, treatment of diseases such as disease resistance enhancemen, sural spasm.
Radix Clematidis: acrid in the mouth is salty, and is warm in nature, poisonous.Go into urinary bladder channel.The effect of Radix Clematidis: wind-damp dispelling, the meridian dredging, expectorant saliva, the hypochondriac lump of loosing.Control gout, insensitive impediment, chills and pain of the waist and kness, beriberi, malaria ， lumps in the chest and abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.Its property benefaction, so the twelve channels and collaterals that can pass through is particularly suitable to whole body migratory rheumatism pain.
Radix Scutellariae: Radix Scutellariae another name Radix Scutellariae, tsuchikane tea root.For the labiate Radix Scutellariae, be used as medicine with root.Heat clearing and damp drying is arranged, and removing heat from blood is antiabortive, detoxicating functions.Cure mainly diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.
Radix Polygoni Multiflori: property is flat, sweet, bitter in the mouth, and property is flat, and GUIXIN, liver, large intestine channel have the effect of detoxifcation, eliminating carbuncle, loosening bowel to relieve constipation, are usually used in treating scrofula carbuncle sore, rubella pruritus, dryness of the intestine constipation and other diseases.
Radix Glycyrrhizae: sweet in the mouth, property is flat; Return 12 warps.Effect: detoxifcation is arranged, eliminate the phlegm, pain relieving, spasmolytic be so that pharmacological action such as anticancer.On the traditional Chinese medical science, the Radix Glycyrrhizae invigorating the spleen and replenishing QI is grown and to be coughed lung moistening, and the emergency detoxifcation is in harmonious proportion hundred medicines.The clinical practice branch " is given birth to and uses " with " processed with honey " not.Give birth to curing mainly laryngopharynx swelling and pain cellulitis skin infection, gastrointestinal ulceration and separate poison of drug, alimentary toxicosis etc.; Processed with honey cures mainly spleen and stomach function and goes down, and big loose stool is thin, weak heating and cough, cardiopalmus etc.
The Chinese medicine and pharmacy theory is thought: from the beginning of the heresy retardance skin that is mostly rheumatic fever, or the neck hyperhidrosis, due to the stiffened cloth friction etc.; The sick impairment of YIN of consumption for a long time liquid, nutrient QI and blood being insufficient, wind syndrome due to blood-deficiency is given birth to dry, and failure of skin and muscle to be nourished forms; Blood-deficiency leading to hyperactivity of the liver, feelings will is unsuccessful, gloomyly do not relax, or nervous tired, flaming up of heart-fire, so that QI-blood circulation dereliction of duty, the skin that stagnates be prone to the key factor that becomes to bring out, and pathogenic feelings is shown effect repeatedly.In a word, feelings will internal injury, ailment said due to cold or exposure invasion and attack are risk factors of primary disease morbidity, and nutrient blood is become estranged, passages through which vital energy circulates loses and dredges, coagulation of QI-blood then is its pathogenesis.Therefore,
Chinese patent medicine of the present invention is followed the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", and all composition comes from the 5th edition medicine that records of China's " pharmacopeia ", and all medicines have temperature compensation liver spleen mutually and altogether; The wind dehumidifying of loosing, the QI and blood regulating, is set upright and is got rid of evils dredge the meridian passage, blood circulation promoting and blood stasis dispelling; Regulate immunologic function, improve skin microcirculation, reach treatment and prevention psoriasis disease, determined curative effect; Have no side effect various Chinese medicine preparation taking conveniences.
The clinical result of use of Chinese patent medicine of the present invention shows to have following advantage:
1, the Chinese medicine each component selected for use of Chinese patent medicine of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment and the prevention psoriasis disease of the Chinese medicine of respectively distinguishing the flavor of, and is harmless to human non-toxic.Acute toxicity test and accumulation toxicity test through white mice and rat show that underproof animal does not see any toxic reaction; Compare zero difference through anatomic observation hemogram, liver function, each organs and tissues morphology finding and matched group, prove that its safety of medicine is reliable.
2, Chinese patent medicine preparation of the present invention need not decoct, not have bitterness sense; Rich in proteins, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid in the medicine; Also contain various trace elements such as Saponin, plant sterol, calcium; Help absorption of human body, health invigorating, and taking convenience.
But 3, Chinese patent medicine preparation of the present invention efficacious therapy psoriasis disease not only; And it is also very obvious to the preventive effect of psoriasis disease; Particularly pass through working in coordination with each other between the medicine, strengthen medicine and treat characteristic separately, through dredge the meridian passage and adjusting immunologic function; Improve the intrinsic healthy energy of patient body and physical and mental health and life quality, reached the healing rehabilitation efficacy preferably.
Further specify Chinese patent medicine of the present invention to treating psoriatic effect through clinical practice below.
One, clinical diagnosis standard:
The position of morbidity is the most common with scalp, is shank, ancon, back, upper arm, forearm, knee, chest and abdominal part and buttocks etc. secondly.Often be symmetry and distribute, also can distribute along tegumentary nerve is the wire arrangement.Skin lesion is from the beginning of for there being the flat pimple of polygon of assembling tendency, the normal or flushing slightly of color of the leather, and lustrous surface or be covered with poor bran skin shape squama is later on owing to constantly scratch or rub; Pimple enlarges gradually, merges in flakes mutually, and the then local skin that continues thickens, and texture is deepened; Intermesh, dry tack free is coarse, and a little canescence squama is arranged, and is lichenification; Skin lesion can rounded or irregular shape patch, clear border, and that touches is coarse.Owing to scratch, near affected part and can also can have new flat hillock rash to occur it with scratch, petechia or blood crusts on every side.Conscious paroxysmal is very itched, and is more acute during by clothing friction and sweat stain, becoming severe at night, and that scratches does not know pain.During anxious state of mind, pruritus is aggravation thereupon also.Because of pruritus can influence work and rest, the patient is often with insomnia, dizzy, irritated symptom.The primary disease course of disease is slow, and constant year does not heal, repeatedly outbreak.
How much be divided into two kinds of general hair style and topical types by its site of pathological change, skin lesion clinically.Topical type, skin lesion is detected in parts such as neck, is the minority boundary plump speckle sheet of lichen appearance clearly; General hair style, it is more extensive to distribute, and good sending out located in head, extremity, shoulder waist etc., even general whole body is everywhere, and the skin lesion characteristics are identical with topical type.
According to psoriatic clinical manifestation and pathological characters, generally be divided into following four types
1, psoriasis vulgaris: erythra generally occurs in scalp, trunk, extremity are stretched side, be red pimple on skin, to occur, and expansion are fused into patch or speckle gradually; There are thicker silvery white phosphorus bits on the surface, out-of-shape, and what have has map or an island appearance outward appearance; The skin lesion that has is less, and is more, is the Caulis et folium pavettae hongkongensis outward appearance; Squama layer one deck comes off, and wipes scurf gently off and can see the red film of very thin one deck, strikes off red film and can see slight petechia; There is person to reveal, medically makes the sieve shape hemorrhage again, homeliness type psoriasis Clinical symptoms that Here it is for blood.
2, erythrodermic psoriasis: be more serious, more rare is a kind of, and this kind of is meant and is the diffusivity redness more than 70% at about whole skin; Kermesinus wellability skin lesion, surface have a large amount of bran skin appearance scurfs, sometimes in the oxter; Thigh root and umbilical part make exfoliation and ooze out because of swelling; Oropharynx nose and eye conjunctiva can be congested rubescent, and the patient often has heating fear of cold, symptoms such as headache and general malaise.
3, pustular psoriasis: divide general property and limitation.Mostly general property pustule type psoriasis is acute onset, can be in a few days to several weeks general whole body of pustule, the intensive potential pimple of needle point size is arranged earlier; Be fused into the pus lake very soon, often with hyperpyrexia, arthralgia and general malaise, the visible leukocytosis of routine blood test chemical examination; After abscess is dry; Desquamation after scurf comes off, has new abscess to occur again immediately.Limitation pustule type psoriasis is seen with palm toe pustule type psoriasis more; With toes portion the symmetry erythema is arranged at the both hands palms, occur syringe needle on the erythema and arrive Li Daxiao greatly to pimple: about 1-2 dries up after week voluntarily, and new pustule appearance is arranged again behind the desquamation; Be continuous repeatedly, the course of disease is obstinate.
4, psoriasis arthropathica: rarely found, any age all can take place, and can betide big or small joint simultaneously, but common be the little joint of wrist, finger and toes, joint of vertebral column also can take place.The joint of pathological changes has redness, pain, serious articular cavity that hydrops is arranged, juxtra-articular skin turgor limitation of activity, joint stiffness of a specified duration; It is thus clear that the X line is down the ruined situation in joint when serious; Erythrocyte sedimentation rate is fast, General Symptomies such as the heat that often occurs together, but rheumatoid agglutinating factor is negative; How psoriasis arthropathica, skin lesion also can only have the skin lesion of homeliness type psoriasic erythema and silver bits with the ostraceous skin lesion of thick picture.
Differential Diagnosis
1. the pathogenic process of acute eczema such as chronic eczema has erubescence, pimple, vesicle, erosion more, ooze out, skin lesion is coarse with plumpness to be main, and with eruption, vesicle, erosion, ooze out, owe clearly on the border, and pathological changes is many bends side at extremity.
2. the skin amyloidosis pilosity is stretched side at back and shank, and skin is the dome pimple of sorghum rice size, and color is purple brown, and matter is harder, and is in groups intensive, and keratinization is coarse.
3. white lump skin lesion substrate is pale red, on cover with silvery white pityrosporum shape squama, thin film phenomenon and petechial hemorrhage are arranged after peelling off.
Two. case selection
All can be used as case for the patient who meets above-mentioned disease and observe, especially weak and sickly, middle-aged and elderly people, women, child are observed as first-selected case especially; The method of observing is then carried out complete observation through the method for hoping, asking, hearing, cutting to the patient; And for of all ages, the sex of the heavier patient of the state of an illness, without exception as the direct study subject of observing treatment.
Three. administrated method
According to psoriatic's severe extent, the length of sick time, treat psoriasis with oral Chinese patent medicine of the present invention in adopting, its method of administration is: three times on the one, each 6-12 gram, warm water delivery service; Ante cibum, one after each meal all can.Just the clothes phase is 30 days, and dose can increase doubly, after this takes medicine continuously by conventional dose, and three months is to observe with curative effect a course of treatment to judge.Chinese patent medicine of the present invention has no side effect through clinical application toxicity test proof because of Chinese patent medicine preparation, reasonable recipe, and therefore, but the patient takes Chinese patent medicine of the present invention the long period during treating, and need not dieting aspect the period in a medicine diet.
Four. curative effect determinate standard
Because psoriasis is the dermatosis that is prone to examine refractory, thereby psoriatic clinical treatment observation index and curative effect judging standard are divided into: during the treatment, treatment finishes the back and visit long term in three periods.
1. treat phase clinical observation and curative effect judging standard
(1) clinical observation
1. squama: the propagation of epidermis cell is quickened and hyperacanthosis, causes cuticular hyperkeratosis, makes epidermis renew the normal fast 7-8 of epidermis of rate doubly, promptly per 3 days left and right sides desquamation one decks.Criterion after the medication is: squama reduces gradually or does not have new skin lesion and appears as effectively, otherwise is invalid.
2. substrate: it shows as substrate infiltration, plumpness, shows that the stratum germinativum propagation of chrotoplast is slowed down, and hyperacanthosis fades, and the substrate skin lesion explain effectively, and the nothing change is soaked in substrate by thick attenuation, plump no attenuation, and it is invalid then to explain.
3. color: because the expansion of corium superficial part vascular plexus and blood capillary, its skin lesion has the non-fading red appearance of pressure more.After the medication, along with the alleviation of the state of an illness, the color of erythra is light red by red stain also, explains effectively, otherwise is invalid.
4. scope: skin lesion many and few indicate the light and heavy of the state of an illness.After the medication, new skin lesion stops to occur, and original erythra begins to dwindle from the edge, or therefrom the mind-set edge disappears gradually, and the erythra that part is big is divided into plurality of small blocks, explain effectively, on the contrary then invalid.
(2) curative effect judging standard:
1. produce effects: in above four, there are three to be clearly better, or four improvement that all have in various degree; Or binomial disappears binomial improvement in addition.
2. effective: as to have binomial to improve or a disappearance.
3. invalid: through one course of treatment of clinical application, skin lesion does not have and improves or increase the weight of.
2. treatment finishes back clinical observation and curative effect judging standard
(1) clinical observation:
1. whether squama: observing has new squama to occur.
2. substrate: whether erythra calms down, the smoothness of skin.
3. color: observe and have or not pigmentation or depigmentation.
4. whether scope: observing has new erythra to occur and the situation that disappears of former skin lesion.
(2) curative effect judging standard:
1. clinical cure: skin lesion all disappears, and only leaves pigmentation or takes off mistake.
2. produce effects: skin lesion disappears more than 70%.
3. effective: skin lesion disappears between the 30-70%.
4. invalid: skin lesion disappears below 30% or is not increased the weight of on the contrary by control.
3. visit clinical observation and curative effect judging standard long term
(1) clinical observation:
1. time: treatment finishes back more than 1 year or 2～three years, visits recovery from illness and recurrence situation.
2. case: visit case and cause of recurrence that observation post cures.
(2) curative effect judging standard:
1. recurrence: the skin lesion area is than enlarging before treating or increasing the weight of.
2. gently recurrence: the recurrence skin lesion is below 50% of former skin lesion.
Five. the clinical treatment result
Chinese patent medicine of the present invention carries out orally taken for curing through all kinds of psoriatics 246 examples that 2006-2010 is accepted for medical treatment in 4 years altogether, male's 126 examples wherein, and women's 120 examples, the age is 16-55 year; Its clinical treatment result according to above-mentioned domestic unified criterion of therapeutical effect statistical computation is: recovery from illness (drug withdrawal observe more than 3 years not recidivist) 91 examples, and cure rate is 36.99%; Produce effects (drug withdrawal observe more than 1 year not recidivist) 83 examples, obvious effective rate is 33.74%; Effective (symptom obviously alleviates the scurf major part and comes off, and still has the few part silver bits person of not moving back) 55 examples, effective percentage is 22.36%; Invalid (take medicine 2 courses of treatment not alleviator) 17 examples, inefficiency 6.91%; Total effective rate is 93.09%, and not seeing has any toxic and side effects.
Model case is introduced:
1 Zhao's root Zhu, the man, 45 years old, live Zhifu District Qiao Shang village, Yantai City, on January 16th, 2008 went to a doctor in the applicant's out-patient department, according to ill 6 years of patient's readme, repeatedly went to see a doctor, and did not all have positive effect and did not cure so far.Through taking Chinese patent medicine of the present invention after course of treatment, the disease significant effective, after this continuous use is promptly fully recovered 9 courses of treatment.Treatment finishes the back not recurrence of visiting more than 2 years.
2, Feng builds, man, 46 years old; Live flourish city, the teacher suffered from psoriasis nearly 15 years; Be illustrated in through others and went to a doctor on March 12nd, 2006, repeatedly gone to see a doctor the folk prescription of also using others to give since patient's readme is ill in the applicant's out-patient department; Bad during fashion, all do not have positive effect and do not cure so far.Take Chinese patent medicine of the present invention after diagnosing after course of treatment, disease is not seen positive effect, but sensation effectively; Patient after this 3 course of treatment sides of continuous use sees obvious curative effects; Continuing to take Chinese patent medicine of the present invention promptly fully recovers 10 courses of treatment.After finishing, treatment visited not recurrence so far more than 3 years.
3, Zhang Hong, the woman 37 years old, lives Zhaoyuan City and recruits cities and towns; The worker suffered from psoriasis nearly 10 years, was illustrated in through others and went to a doctor in the applicant's out-patient department on May 18th, 2008, and the patient has repeatedly gone to see a doctor since ill; The folk prescription of also using others to give, bad during fashion, but do not cure so far.Take Chinese patent medicine of the present invention after diagnosing after course of treatment, the visible positive effect of disease; Patient after this continuous use promptly fully recovers 6 courses of treatment.After finishing, treatment visited not recurrence so far more than 1 year.
The specific embodiment
Embodiment 1
The described Chinese patent medicine of present embodiment is to press the row weight portion to take by weighing each Chinese crude drug: 10 parts of Radix Sophorae Flavescentiss; 10 parts of Cortex Phellodendris; 20 parts of Semen Coicis; 20 parts of favus skins; 30 parts in the Radix Rehmanniae; 10 parts of Radix Paeoniae Rubra; 10 parts of Fructus Arctiis; 10 parts of the Fructus Kochiae; 10 parts in Herba Spirodelae; 20 parts of Pulvis Talci; 10 parts of Cortex Moutans; 10 parts of Bombyx Batryticatus; 30 parts of Flos Loniceraes; 10 parts of Herba Schizonepetae; 10 parts of the Rhizoma Anemarrhenaes; 20 parts of the Radix Paeoniae Albas; 20 parts of Radix Ophiopogonis; 20 parts in Colla Corii Asini; 20 parts of Radix Adenophorae (Radix Glehniae); Windproof 10 parts; 10 parts of Fructus Chaenomeliss; 10 parts of Radix Clematidis; 10 parts of Radix Scutellariaes; 30 parts of Radix Polygoni Multifloris; 20 parts in Radix Glycyrrhizae.
The described Chinese patent medicine of present embodiment is that its preparation technology is: above-mentioned each medicinal raw material is processed sublimed preparation according to the pharmaceutical methods that routine prepares sublimed preparation as the psoriatic endo-medicine of treatment.
Embodiment 2
Press the row weight portion and take by weighing each medical material: 30 parts of Radix Sophorae Flavescentiss, 30 parts of Cortex Phellodendris, 50 parts of Semen Coicis, 50 parts of favus skins, 60 parts in the Radix Rehmanniae, 30 parts of Radix Paeoniae Rubra, 30 parts of Fructus Arctiis, 30 parts of the Fructus Kochiae, 30 parts in Herba Spirodelae, 50 parts of Pulvis Talci, 30 parts of Cortex Moutans, 30 parts of Bombyx Batryticatus, 60 parts of Flos Loniceraes, 30 parts of Herba Schizonepetae, 30 parts of the Rhizoma Anemarrhenaes, 50 parts of the Radix Paeoniae Albas, 50 parts of Radix Ophiopogonis, 50 parts in Colla Corii Asini, 50 parts of Radix Adenophorae (Radix Glehniae), windproof 30 parts, 30 parts of Fructus Chaenomeliss, 30 parts of Radix Clematidis, 30 parts of Radix Scutellariaes, 60 parts of Radix Polygoni Multifloris, 50 parts in Radix Glycyrrhizae.
The described Chinese patent medicine of present embodiment is that its preparation technology is: above-mentioned each medicinal raw material is processed packed powder according to the pharmaceutical methods that routine prepares powder as the psoriatic endo-medicine of treatment.
Embodiment 3
Press the row weight portion and take by weighing each medical material: 15 parts of Radix Sophorae Flavescentiss, 15 parts of Cortex Phellodendris, 30 parts of Semen Coicis, 30 parts of favus skins, 40 parts in the Radix Rehmanniae, 15 parts of Radix Paeoniae Rubra, 15 parts of Fructus Arctiis, 15 parts of the Fructus Kochiae, 15 parts in Herba Spirodelae, 30 parts of Pulvis Talci, 15 parts of Cortex Moutans, 15 parts of Bombyx Batryticatus, 40 parts of Flos Loniceraes, 15 parts of Herba Schizonepetae, 15 parts of the Rhizoma Anemarrhenaes, 30 parts of the Radix Paeoniae Albas, 30 parts of Radix Ophiopogonis, 30 parts in Colla Corii Asini, 30 parts of Radix Adenophorae (Radix Glehniae), windproof 15 parts, 15 parts of Fructus Chaenomeliss, 15 parts of Radix Clematidis, 15 parts of Radix Scutellariaes, 40 parts of Radix Polygoni Multifloris, 30 parts in Radix Glycyrrhizae.
The described Chinese patent medicine of present embodiment is that its preparation technology is: above-mentioned each medicinal raw material is processed capsule according to the pharmaceutical methods that routine prepares capsule as the psoriatic endo-medicine of treatment.
Embodiment 4
Press the row weight portion and take by weighing each medical material: 25 parts of Radix Sophorae Flavescentiss, 25 parts of Cortex Phellodendris, 40 parts of Semen Coicis, 40 parts of favus skins, 50 parts in the Radix Rehmanniae, 25 parts of Radix Paeoniae Rubra, 25 parts of Fructus Arctiis, 25 parts of the Fructus Kochiae, 25 parts in Herba Spirodelae, 40 parts of Pulvis Talci, 25 parts of Cortex Moutans, 25 parts of Bombyx Batryticatus, 50 parts of Flos Loniceraes, 25 parts of Herba Schizonepetae, 25 parts of the Rhizoma Anemarrhenaes, 40 parts of the Radix Paeoniae Albas, 40 parts of Radix Ophiopogonis, 40 parts in Colla Corii Asini, 40 parts of Radix Adenophorae (Radix Glehniae), windproof 25 parts, 25 parts of Fructus Chaenomeliss, 25 parts of Radix Clematidis, 25 parts of Radix Scutellariaes, 50 parts of Radix Polygoni Multifloris, 40 parts in Radix Glycyrrhizae.
The described Chinese patent medicine of present embodiment is as the psoriatic endo-medicine of treatment; Its preparation technology is: above-mentioned each medicinal raw material is processed tablet according to the pharmaceutical methods that routine prepares tablet; (like conventional tablet, sugar coated tablet, film coated tablet etc.), and give conventional drug excipient (like starch, sucrose, lactose, calcium stearate, magnesium stearate etc.).
Embodiment 5
Press the row weight portion and take by weighing each medical material: 20 parts of Radix Sophorae Flavescentiss, 20 parts of Cortex Phellodendris, 30 parts of Semen Coicis, 30 parts of favus skins, 45 parts in the Radix Rehmanniae, 20 parts of Radix Paeoniae Rubra, 20 parts of Fructus Arctiis, 20 parts of the Fructus Kochiae, 20 parts in Herba Spirodelae, 30 parts of Pulvis Talci, 20 parts of Cortex Moutans, 20 parts of Bombyx Batryticatus, 45 parts of Flos Loniceraes, 20 parts of Herba Schizonepetae, 20 parts of the Rhizoma Anemarrhenaes, 30 parts of the Radix Paeoniae Albas, 30 parts of Radix Ophiopogonis, 30 parts in Colla Corii Asini, 30 parts of Radix Adenophorae (Radix Glehniae), windproof 20 parts, 20 parts of Fructus Chaenomeliss, 20 parts of Radix Clematidis, 20 parts of Radix Scutellariaes, 45 parts of Radix Polygoni Multifloris, 30 parts in Radix Glycyrrhizae.
The described Chinese patent medicine of present embodiment is that its preparation technology is as the psoriatic endo-medicine of treatment: above-mentioned each medicinal raw material is processed pill according to the pharmaceutical methods that routine prepares pill, and give conventional drug excipient.
Embodiment 6
Press the row weight portion and take by weighing each medical material: 20 parts of Radix Sophorae Flavescentiss, 20 parts of Cortex Phellodendris, 35 parts of Semen Coicis, 35 parts of favus skins, 45 parts in the Radix Rehmanniae, 20 parts of Radix Paeoniae Rubra, 20 parts of Fructus Arctiis, 20 parts of the Fructus Kochiae, 20 parts in Herba Spirodelae, 35 parts of Pulvis Talci, 20 parts of Cortex Moutans, 20 parts of Bombyx Batryticatus, 45 parts of Flos Loniceraes, 20 parts of Herba Schizonepetae, 20 parts of the Rhizoma Anemarrhenaes, 35 parts of the Radix Paeoniae Albas, 35 parts of Radix Ophiopogonis, 35 parts in Colla Corii Asini, 35 parts of Radix Adenophorae (Radix Glehniae), windproof 20 parts, 20 parts of Fructus Chaenomeliss, 20 parts of Radix Clematidis, 20 parts of Radix Scutellariaes, 45 parts of Radix Polygoni Multifloris, 35 parts in Radix Glycyrrhizae.
The described Chinese patent medicine of present embodiment is that its preparation technology is: above-mentioned each medicinal raw material is processed granule according to the pharmaceutical methods that routine prepares granule as the psoriatic endo-medicine of treatment.
Claims (6)
1. psoriatic Chinese patent medicine of treatment is characterized in that being prepared from following medicaments in part by weight: Radix Sophorae Flavescentis 10-30 part, Cortex Phellodendri 10-30 part, Semen Coicis 20-50 part, favus skin 20-50 part, Radix Rehmanniae 30-60 part, Radix Paeoniae Rubra 10-30 part, Fructus Arctii 10-30 part, Fructus Kochiae 10-30 part, Herba Spirodelae 10-30 part, Pulvis Talci 20-50 part, Cortex Moutan 10-30 part, Bombyx Batryticatus 10-30 part, Flos Lonicerae 30-60 part, Herba Schizonepetae 10-30 part, Rhizoma Anemarrhenae 10-30 part, Radix Paeoniae Alba 20-50 part, Radix Ophiopogonis 20-50 part, Colla Corii Asini 20-50 part, Radix Adenophorae (Radix Glehniae) 20-50 part, windproof 10-30 part, Fructus Chaenomelis 10-30 part, Radix Clematidis 10-30 part, Radix Scutellariae 10-30 part, Radix Polygoni Multiflori 30-60 part, Radix Glycyrrhizae 20-50 part.
2. the psoriatic Chinese patent medicine of treatment according to claim 1 is characterized in that being prepared from following medicaments in part by weight: Radix Sophorae Flavescentis 15-25 part, Cortex Phellodendri 15-25 part, Semen Coicis 30-40 part, favus skin 30-40 part, Radix Rehmanniae 40-50 part, Radix Paeoniae Rubra 15-25 part, Fructus Arctii 15-25 part, Fructus Kochiae 15-25 part, Herba Spirodelae 15-25 part, Pulvis Talci 30-40 part, Cortex Moutan 15-25 part, Bombyx Batryticatus 15-25 part, Flos Lonicerae 40-50 part, Herba Schizonepetae 15-25 part, Rhizoma Anemarrhenae 15-25 part, Radix Paeoniae Alba 30-40 part, Radix Ophiopogonis 30-40 part, Colla Corii Asini 30-40 part, Radix Adenophorae (Radix Glehniae) 30-40 part, windproof 15-25 part, Fructus Chaenomelis 15-25 part, Radix Clematidis 15-25 part, Radix Scutellariae 15-25 part, Radix Polygoni Multiflori 40-50 part, Radix Glycyrrhizae 30-40 part.
3. the psoriatic Chinese patent medicine of treatment according to claim 1 is characterized in that being prepared from following medicaments in part by weight: 20 parts of Radix Sophorae Flavescentiss, 20 parts of Cortex Phellodendris, 35 parts of Semen Coicis, 35 parts of favus skins, 45 parts in the Radix Rehmanniae, 20 parts of Radix Paeoniae Rubra, 20 parts of Fructus Arctiis, 20 parts of the Fructus Kochiae, 20 parts in Herba Spirodelae, 35 parts of Pulvis Talci, 20 parts of Cortex Moutans, 20 parts of Bombyx Batryticatus, 45 parts of Flos Loniceraes, 20 parts of Herba Schizonepetae, 20 parts of the Rhizoma Anemarrhenaes, 35 parts of the Radix Paeoniae Albas, 35 parts of Radix Ophiopogonis, 35 parts in Colla Corii Asini, 35 parts of Radix Adenophorae (Radix Glehniae), windproof 20 parts, 20 parts of Fructus Chaenomeliss, 20 parts of Radix Clematidis, 20 parts of Radix Scutellariaes, 45 parts of Radix Polygoni Multifloris, 35 parts in Radix Glycyrrhizae.
4. according to the psoriatic Chinese patent medicine of the described treatment of the arbitrary claim of claim 1 to 3, it is characterized in that described Chinese patent medicine processes the oral medicine dosage form of pill, sublimed preparation, powder, tablet, unguentum, decoction and capsule dress powder according to the conventional technology of preparing of Chinese medicine.
5. the psoriatic Chinese patent medicine of treatment according to claim 4 is characterized in that described Chinese patent medicine also contains drug excipient.
6. the psoriatic Chinese patent medicine of the described treatment of the arbitrary claim of claim 1-3 is characterized in that described Chinese patent medicine is used for the application as treatment psoriasis disease.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104036390A CN102416117A (en) | 2011-11-29 | 2011-11-29 | Chinese patent medicine for treating psoriasis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011104036390A CN102416117A (en) | 2011-11-29 | 2011-11-29 | Chinese patent medicine for treating psoriasis |
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| CN102416117A true CN102416117A (en) | 2012-04-18 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805835A (en) * | 2012-09-06 | 2012-12-05 | 韩秀芳 | Method for treating psoriasis by traditional Chinese medicine |
| CN102988685A (en) * | 2012-11-13 | 2013-03-27 | 黄文珍 | Traditional Chinese medicine composition for treating dermatophyte or eczema and preparation method thereof |
| CN103110851A (en) * | 2013-01-17 | 2013-05-22 | 刘凤华 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
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2011
- 2011-11-29 CN CN2011104036390A patent/CN102416117A/en active Pending
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| 杨景海主编: "《21世纪健康新概念丛书·新中医效验秘方宝典》", 28 February 2005, 人民日报出版社 * |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805835A (en) * | 2012-09-06 | 2012-12-05 | 韩秀芳 | Method for treating psoriasis by traditional Chinese medicine |
| CN102988685A (en) * | 2012-11-13 | 2013-03-27 | 黄文珍 | Traditional Chinese medicine composition for treating dermatophyte or eczema and preparation method thereof |
| CN102988685B (en) * | 2012-11-13 | 2015-02-11 | 黄文珍 | Traditional Chinese medicine composition for treating dermatophyte or eczema and preparation method thereof |
| CN103110851A (en) * | 2013-01-17 | 2013-05-22 | 刘凤华 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
| CN103110851B (en) * | 2013-01-17 | 2014-11-12 | 王建宁 | Traditional Chinese medicine composition for treating psoriasis and preparation method thereof |
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Application publication date: 20120418 |