CN103110851B - Traditional Chinese medicine composition for treating psoriasis and preparation method thereof - Google Patents

Traditional Chinese medicine composition for treating psoriasis and preparation method thereof Download PDF

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CN103110851B
CN103110851B CN201310017008.4A CN201310017008A CN103110851B CN 103110851 B CN103110851 B CN 103110851B CN 201310017008 A CN201310017008 A CN 201310017008A CN 103110851 B CN103110851 B CN 103110851B
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radix
cortex
psoriasis
chinese medicine
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CN103110851A (en
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王建宁
司晓青
王万忠
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Jiangxi Bofen Medical Devices Co ltd
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Abstract

The invention discloses a traditional Chinese medicine composition for treating psoriasis, which mainly comprises herba schizonepetae, radix saposhnikoviae, zanthoxylum bungeanum, gentiana scabra bunge, periostracum cicadae, cortex dictamni, fructus kochiae, coix seed, zoacys dhumnades, cortex moutan radicis, radix ophiopogonis, radix paeoniae rubra, fructus forsythia, salvia miltiorrhiz, herba taraxaci, semen persicae, amur corktree bark and rhizoma polygoni cuspidate. The traditional Chinese medicine composition can effectively treat rashes caused by the psoriasis, has the effects on stopping itch and pain, has good cure effect on the psoriasis, has the characteristics of safety, effects and no any side effect, and can treat the psoriasis.

Description

A kind of psoriatic Chinese medicine composition and preparation method thereof for the treatment of
Technical field
The invention discloses a kind of Chinese medicine composition, especially treat psoriatic Chinese medicine composition and preparation method thereof.Belong to Chinese medicine field.
Background technology
Psoriasis, is commonly called as " psoriasis ", and Chinese medicine is referred to as " white Mange ", has again the names of disease such as " psoriasis ", " chronic eczema ", is a kind of common chronic inflammatory disease dermatoses.It belongs to the disease of polygenic inheritance, can be by multiple motivating factor, as wound, infection, medicine etc. all may bring out this disease in susceptible individual.Typical cutaneous manifestations is the red speckle that boundary clearly has silvery white squama.The lighter can show as the patella ulnaris position speckle of several silver coin sizes, and severe one also can be got involved by whole skin.Its physiological pathology mechanism is mainly the abnormal and immune activation of epidermal hyperplasia differentiation.
Different according to clinical manifestation, psoriasis is divided into four types: 1. psoriasis vulgaris is a most common clinical type.The skin lesion initial stage is red pimple or maculopapule, and foxtail millet grain, to Semen phaseoli radiati size, can expand gradually and be fused into red patch later, and boundary is clear, and substrate infiltrates obviously, and skin lesion surface is covered with multilamellar silvery white squama, easily strikes off.Remove the shinny thin film of the visible one deck pale red of surperficial squama, then strike off thin film, occur the sieve little petechia of shape, be called " petechial hemorrhage phenomenon ".White squama, shinny thin film and petechial hemorrhage are the Clinical symptoms of primary disease; 2. psoriasis pustulosa, more rare clinically, accounts for psoriatic's 0.77%.Generally can be divided into 2 kinds, general property pustule type and Pasfulosis palmaris et plantaris type.General property pustule type be everlasting malpractice, medicine for external use stimulates or Hormone Withdrawal subtracts morbidity under the inspiring of the factor such as too fast.Acute onset, skin lesion is many on the basic lesions of psoriasis vulgaris or occur the large yellow shallow pimple of foxtail millet grain around, with extremity bend side and gauffer position common.There is intensive pustule in the visible whole body of severe patient, pustule is fused into pus lake, and the rubescent swelling of whole skin can be with heating, arthralgia, general malaise etc.Pasfulosis palmaris et plantaris type skin lesion is detected in palm sole of the foot portion, occurs the intensive large pimple of foxtail millet grain on erythema basis, and bleb wall is difficult for breaking, 2 weeks dry and hard crusts of left and right bleb, decortication.Pustule Chang Fanfu occurs, and skin lesion can gradually diffuse to palm toe dorsal part towards periphery; 3., outside patient's desilver bits disease damage evil, also can there is symptoms of rheumatoid arthritis, incidence rate approximately 6.8% in psoriasis arthropathica.Its joint symptom and skin symptom increase the weight of simultaneously or alleviate.After majority of cases is often secondary to psoriasis, or with psoriasis pustulosa or erythrodermic psoriasis and see.Pathological changes can be invaded big or small joint, but with little joints such as hands, wrist and foots, refers to that especially sole of the foot end joint is common.These joint congestion and swelling pains, stiff even amyotrophy; 4. Folium Styracis Suberifoliae psoriasis pustulosa, claims again psoriasis exfoliative dermatitis, accounts for psoriatic's 1%.The clinical state of an illness is heavier, how by psoriasis vulgaris at the phase of carrying out medicine for external use stimulation or malpractice and cause.Clinical manifestation is exfoliative dermatitis, and common whole skin fills the air flushing, swelling, and a large amount of bran defurfurations, palm toe keratinization, first thickens even and comes off.Now the feature of psoriasis vulgaris often disappears, but more, has as seen the skin lesion of small pieces psoriasis vulgaris.Patient is often with symptoms such as heating, fear of cold, headache discomforts, and whole body superficial lymph is tied enlargement.
The psoriasis course of disease is long, easily outbreak repeatedly, sustainable more than 10 years or decades.Most of patient increases the weight of or recur winter, and spring and summer alleviates or disappears season.Generally be divided into for three phases: 1. carry out the phase: newly rash constantly occurs, old rash constantly expands, and skin lesion color is scarlet, infiltrate obviously, squama is thick long-pending, and acute pruritus, can have isomorphic response; 2. resting stage: the state of an illness remains static, occurs without new rash substantially, and former erythra also loses and disappears; 3. catagen: erythra infiltrates attenuation, and color is thin out, squama reduces.Erythra starts to dwindle, and occurs that light color is dizzy, finally leaves over depigmentation macule or pigmentation spots around.Also visible skin lesion, from central clearing, is polygon change or petal sample and changes.
Treatment psoriasis should be followed following principle: 1. safety: various Therapeutic Method all should be take the safety of guaranteeing patient for primarily, can not there is serious adverse reaction for pursuing short term effect. should not make patient without physician guidance in the situation that, prolonged application is to its healthy harmful method; 2. individuation: when selecting therapeutic scheme, consider comprehensively psoriatic the state of an illness, demand, tolerance level, ability to shoulder economically, previously treat the untoward reaction of history and medicine etc., comprehensively, reasonably select to formulate therapeutic scheme.
Because psoriasis is a kind of chronic disease, and it is wider to involve crowd, and the life impact that it causes patient is very large.Pruritus, squama and visible speckle are puzzlement patient's subject matter.
The traditional Chinese medical science adopts and follows the method for levying medical science, and the dialectical differential diagnosis of diseases of psoriatic clinical manifestation and the traditional Chinese medical science is combined.
In the method for existing Psoriasis Treated by TCM, Chinese invention patent application CN02134397.7 discloses a kind of by name " a kind of treat psoriatic liquid medicine of exterior coating " on January 8th, 2003, its charcoal powder by alligator oil, Oleum Arachidis hypogaeae semen, mistake 100 mesh sieves is, dried Alumen and the vaseline of 100 mesh sieves form excessively, prepare burden expensive and be not easy to obtain, preparation method is complicated, and it is external-applied ointment, cannot reach the object of radical cure.
Summary of the invention
For the present situation of existing treatment psoriasis deficiency, one of object of the present invention is to provide a kind of psoriatic Chinese medicine composition for the treatment of, and has feature easy to operate, evident in efficacy, and its adopts comparatively common in the localities Chinese crude drug as raw material, with low cost.
Another object of the present invention is just to provide the psoriatic preparation method of above-mentioned treatment.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a psoriatic Chinese medicine composition, preferred proportioning, takes off the primary raw material of stating weight proportion and is prepared from: Herba Schizonepetae 4.5-9 part, Radix Saposhnikoviae 4.5-9 part, Pericarpium Zanthoxyli 3-6 part, Radix Gentianae 3-6 part, Periostracum Cicadae 3-6 part, Cortex Dictamni 4.5-9 part, Fructus Kochiae 9-15 part, Semen Coicis 9-30 part (preferred, Semen Coicis 9.5-29.5 part), Zaocys 9-12 part, Cortex Moutan 6-12 part, Radix Ophiopogonis 6-12 part, Radix Paeoniae Rubra 6-12 part, Fructus Forsythiae 6-15 part, Radix Salviae Miltiorrhizae 9-15 part, Herba Taraxaci 9-15 part, Semen Persicae 4-9 part, Cortex Phellodendri 3-12 part, Rhizoma Polygoni Cuspidati 9-15 part.
Treat a psoriatic Chinese medicine composition, more preferably proportioning, takes off the primary raw material of stating weight proportion and is prepared from: Herba Schizonepetae 5-8 part, Radix Saposhnikoviae 5-8 part, Pericarpium Zanthoxyli 3.5-5 part, Radix Gentianae 3.5-5 part, Periostracum Cicadae 3.5-5 part, Cortex Dictamni 5-8 part, Fructus Kochiae 10-14 part, Semen Coicis 12-25 part, Zaocys 9.5-11 part, Cortex Moutan 7-11 part, Radix Ophiopogonis 7-11 part, Radix Paeoniae Rubra 7-11 part, Fructus Forsythiae 8-12 part, Radix Salviae Miltiorrhizae 10-13 part, Herba Taraxaci 10-14 part, Semen Persicae 5-8 part, Cortex Phellodendri 4-10 part, Rhizoma Polygoni Cuspidati 10-14 part.
Treat a psoriatic Chinese medicine composition, best proportioning, takes off the primary raw material of stating weight proportion and is prepared from: 7 parts of Herba Schizonepetae, 7 parts of Radix Saposhnikoviaes, 4 parts, Pericarpium Zanthoxyli, 4 parts of Radix Gentianae, 4 parts of Periostracum Cicadaes, 6 parts of Cortex Dictamni, 12 parts of the Fructus Kochiae, 20 parts of Semen Coiciss, 10 parts of Zaocyss, 9 parts of Cortex Moutans, 8 parts of Radix Ophiopogonis, 9 parts of Radix Paeoniae Rubra, 10 parts of Fructus Forsythiaes, 12 parts of Radix Salviae Miltiorrhizaes, 12 parts of Herba Taraxacis, 6 parts, Semen Persicae, 6 parts of Cortex Phellodendris, 12 parts of Rhizoma Polygoni Cuspidati.
Treat a psoriatic Chinese medicine composition preparation method, preparation process is as follows:
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in the interior cold water soak 15-35 minute that uses of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 20-50 minute at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 20-45 minute at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 2000-6000 milliliter again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
Above-mentioned preparation method, 1. step uses cold water soak 15-35 minute (preferably 20-30 minute, is more preferably 25 minutes).
Above-mentioned preparation method, step 1. 20-50 at a simmer minute (preferably 25-40 minute, is more preferably 30 minutes).
Above-mentioned preparation method, is characterized in that, 2. step turns 20-45 at a simmer minute (preferably 25-35 minute, is more preferably 30 minutes).
Above-mentioned preparation method, is characterized in that, 3. step is blended into the water of 2000-6000 milliliter (preferably 3000-5500, is more preferably 4000 milliliters) again.
Using method: for making the present invention reach optimum therapeuticing effect, Chinese medicine composition of the present invention, the medicinal liquid of twice mixing is divided into 2 parts, in sooner or later taking half an hour after meal; The medicinal liquid of decocting for the third time, once a day, drip washing affected part.
This Chinese medicine composition is remarkable to psoriatic effect, not only has effect antipruritic, that peeling rash etc. is controlled table disease, can also fundamentally thoroughly treat psoriasis, and can be for the different reason determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of psoriasis.Local common medical material for multiselect of the present invention, cheap, alleviated patient's financial burden.
Treat a psoriatic Chinese medicine composition, the pharmacological effect of each crude drug is respectively:
Herba Schizonepetae: acrid in the mouth, micro-hardship, slightly warm in nature.There is the loose wind that induces sweat, rash, the skin ulcer that disappears, the effect of hemostasis, for furuncle, cold, fever.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.For inducing sweat, dispel the wind medicine, there is expelling pathogenic wind from the body surface, removing dampness to relieve pain, antipruritic effect, for affection of exogenous wind-cold, rheumatic arthralgia, rubella pruritus.
Pericarpium Zanthoxyli: acrid in the mouth, warm in nature.There is warming middle-JIAO to relieve pain, the effect of killing parasites for relieving itching, for coldness and pain in the epigastrium, vomiting is had loose bowels, external treatment eczema pruritus.
Radix Gentianae: bitter in the mouth, cold in nature.There is heat clearing and damp drying, the effect of clearing away heat-fire, for damp invasion of lower energizer, headache conjunctival congestion, Hiccough and deaf.
Periostracum Cicadae: sweet in the mouth, cold in nature.There is loose wind heat extraction, the effect of rash, for anemopyretic cold, pharyngalgia, rubella pruritus, convulsion with spasms.
Cortex Dictamni: bitter in the mouth, salty, cold in nature.There is heat clearing and damp drying, dispelling wind for relieving itching, the effect of removing toxic substances, for rubella, eczema, the scabies due to wind heat noxious dampness.
The Fructus Kochiae: acrid in the mouth, hardship, cold in nature.There is clearing away heat-damp and promoting diuresis, the effect of dispelling wind for relieving itching, for rubella, eczema, skin pruritus.
Semen Coicis: sweet in the mouth, light, cool in nature.There is spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, for edema, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Zaocys: sweet in the mouth, property is flat.Dispel the wind, dredging collateral, the effect of relieving convulsion, for rheumatoid arthritis stubborn, leprosy scabies, malignant boil.
Cortex Moutan: bitter in the mouth, pungent, cold in nature.There is clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis, for deficiency of YIN osteopyrexia and fever, carbuncle sore tumefacting virus, rheumatism pyretic arthralgia.
Radix Ophiopogonis: sweet in the mouth, micro-hardship, cold nature.Have YIN nourishing and the production of body fluid promoting, the effect that lung moistening clears away heart-fire, quenches one's thirst for interior-heat, vexed insomnia.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.There is clearing away heat and cooling blood, the effect of eliminating stasis to stop pain, for maculae caused by violent heat pathogen, hypochondriac pain due to stagnation of liverQI.
Fructus Forsythiae: bitter in the mouth, cold nature.There is heat-clearing and toxic substances removing, the loose swollen effect of the knot that disappears, for anemopyretic cold, heating, macule, carbuncle pyogenic infections from tumour or sore.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.Invigorate blood circulation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the effect of the relieving restlessness that clears away heart-fire, for pyretic arthralgia pain, skin infection swells and ache.
Herba Taraxaci: sweet in the mouth, bitter in the mouth, cold in nature.There is heat-clearing and toxic substances removing, the effect of dispersing swelling and dissipating binds, for carbuncle furuncle furuncle, furuncle carbuncle toxin, heating.
Semen Persicae: bitter in the mouth, sweet, property is flat.There is blood circulation promoting and blood stasis dispelling, the effect of loosening bowel to relieve constipation.
Cortex Phellodendri: bitter in the mouth, cold in nature.There is heat clearing and damp drying, the effect of eliminating fire and detoxication, for hectic fever due to YIN-deficiency consumptive fever, sore swollen toxin, eczema pruritus.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature.There is heat-clearing and toxic substances removing, expelling wind and removing dampness, the effect of dissipating blood stasis analgesic therapy, for arthralgia, damp and hot, too fat to move sore.
Chinese medicine composition of the present invention is based on the psoriatic principle of traditional Chinese medical herbal treatment.The Chinese medicinal material of selecting has toxin expelling, removing heat from blood, and the hot effect of dispelling, and cheap, life-time service also can not cause patient's financial burden, is the comparatively desirable medicine for the treatment of psoriasis.
The specific embodiment
Below in conjunction with embodiment and experimental example, describe technical scheme of the present invention in detail, but protection domain is not by this restriction.
embodiment 1
4.5 grams of Herba Schizonepetae, 4.5 grams of Radix Saposhnikoviaes, 3 grams, Pericarpium Zanthoxyli, 3 grams of Radix Gentianae, 3 grams of Periostracum Cicadaes, 4.5 grams of Cortex Dictamni, 9 grams of the Fructus Kochiae, 9 grams of Semen Coiciss, 9 grams of Zaocyss, 6 grams of Cortex Moutans, 6 grams of Radix Ophiopogonis, 6 grams of Radix Paeoniae Rubra, 6 grams of Fructus Forsythiaes, 9 grams of Radix Salviae Miltiorrhizaes, 9 grams of Herba Taraxacis, 4 grams, Semen Persicae, 3 grams of Cortex Phellodendris, 9 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 15 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 20 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 2000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
embodiment 2
5 grams of Herba Schizonepetae, 5 grams of Radix Saposhnikoviaes, 3.5 grams, Pericarpium Zanthoxyli, 3.5 grams of Radix Gentianae, 3.5 grams of Periostracum Cicadaes, 5 grams of Cortex Dictamni, 10 grams of the Fructus Kochiae, 12 grams of Semen Coiciss, 9.5 grams of Zaocyss, 7 grams of Cortex Moutans, 7 grams of Radix Ophiopogonis, 7 grams of Radix Paeoniae Rubra, 8 grams of Fructus Forsythiaes, 10 grams of Radix Salviae Miltiorrhizaes, 10 grams of Herba Taraxacis, 5 grams, Semen Persicae, 4 grams of Cortex Phellodendris, 10 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 20 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 25 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 25 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 3000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
embodiment 3
8 grams of Herba Schizonepetae, 8 grams of Radix Saposhnikoviaes, 5 grams, Pericarpium Zanthoxyli, 5 grams of Radix Gentianae, 5 grams of Periostracum Cicadaes, 8 grams of Cortex Dictamni, 14 grams of the Fructus Kochiae, 25 grams of Semen Coiciss, 11 grams of Zaocyss, 11 grams of Cortex Moutans, 11 grams of Radix Ophiopogonis, 11 grams of Radix Paeoniae Rubra, 12 grams of Fructus Forsythiaes, 13 grams of Radix Salviae Miltiorrhizaes, 14 grams of Herba Taraxacis, 8 grams, Semen Persicae, 10 grams of Cortex Phellodendris, 14 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 30 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 40 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 5500 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
embodiment 4
9 grams of Herba Schizonepetae, 9 grams of Radix Saposhnikoviaes, 6 grams, Pericarpium Zanthoxyli, 6 grams of Radix Gentianae, 6 grams of Periostracum Cicadaes, 9 grams of Cortex Dictamni, 15 grams of the Fructus Kochiae, 30 grams of Semen Coiciss, 12 grams of Zaocyss, 12 grams of Cortex Moutans, 12 grams of Radix Ophiopogonis, 12 grams of Radix Paeoniae Rubra, 15 grams of Fructus Forsythiaes, 15 grams of Radix Salviae Miltiorrhizaes, 15 grams of Herba Taraxacis, 9 grams, Semen Persicae, 12 grams of Cortex Phellodendris, 15 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 35 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 50 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 45 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 6000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
embodiment 5
7 grams of Herba Schizonepetae, 7 grams of Radix Saposhnikoviaes, 4 grams, Pericarpium Zanthoxyli, 4 grams of Radix Gentianae, 4 grams of Periostracum Cicadaes, 6 grams of Cortex Dictamni, 12 grams of the Fructus Kochiae, 20 grams of Semen Coiciss, 10 grams of Zaocyss, 9 grams of Cortex Moutans, 8 grams of Radix Ophiopogonis, 9 grams of Radix Paeoniae Rubra, 10 grams of Fructus Forsythiaes, 12 grams of Radix Salviae Miltiorrhizaes, 12 grams of Herba Taraxacis, 6 grams, Semen Persicae, 6 grams of Cortex Phellodendris, 12 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 25 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 30 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 30 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 4000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
Using method: for making the present invention reach optimum therapeuticing effect, Chinese medicine composition of the present invention, the medicinal liquid of twice mixing is divided into 2 parts, in sooner or later taking half an hour after meal; The medicinal liquid of decocting for the third time, once a day, drip washing affected part.
model case one
Open XX, female, 26 years old, Changdao County, Yantai City Nan Changshanzhen., also there is afterwards erythema, the scurf of size as copper coin with it in symptom: head has point erythema, scurf.Symptom develops into whole body very soon subsequently, the erythema of extremity, the scurf picture map of ining succession, and pruritus is hard to bear, scratch grab rear bloodstained, painful very much.Through hospital diagnosis, be psoriasis, the money for the treatment of is spent very much, but Relapse rate is difficult.Sick age: 8 years.Examine the time: on May 19th, 2011; Use Chinese medicine composition of the present invention, oral medicine, one day twice, in sooner or later taking half an hour after meal, medicinal liquid drip washing affected part, once a day; Use pruritus symptom on the same day alleviates; Use 15 days scurfs obviously to reduce, pruritus transference cure; Use 1 month scurf to disappear more than half; Use 1 first quarter moon erythema, scurf disappears, and symptom disappears completely, recovers; Use again Chinese medicine composition of the present invention to consolidate 10 days, drug withdrawal is so far without recurrence.
model case two
Thank to XX, man, 24 years old, Jining City in Shandong Province Liangshan County.Symptom: while being educated in the university, dormitory, without normal open wind, makes moist and causes that head occurs that drop shape is with squama, without alopecia phenomenon.In ear, there is squama Rhizoma Euonymus companion pruritus.Elbow place is symmetrical speckle shape, and quantity is many.Back has large one of palm near spinal column both sides, and external genital has two drop pimples, and it is scattered that affected part distributes, and with pruritus, by hospital diagnosis, be psoriasis, once uses halcinonide emulsion, tinea is clear, compound recipe ammonia peptide therapeutic effect is all bad.Sick age: 3 years.Examine the time: on November 14th, 2011; Use Chinese medicine composition of the present invention, oral medicine, one day twice, in sooner or later taking half an hour after meal, medicinal liquid drip washing affected part, once a day; Use pruritus symptom on the same day alleviates, and pimple reduces; Use 3 days, pimple disappears, and squama reduces; Use 10 days, speckle starts obviously to disappear; Use 15 days, all transference cures, recover; Use appearance without any side effects during Chinese medicine composition of the present invention.
model case three
Grandson XX, female, 25 years old, Shanghe County, Jinan City, Shandong Province.Originally just on ancon and arm, there are some slight little red stains, afterwards due to malpractice, cause in a short period of time that sb.'s illness took a turn for the worse, whole body is all red pimple now, surface is with multilamellar silvery white flakey scurf, pruritus, pain from head to foot, whole body desquamation, local with skin lesion (festering) phenomenon.Sick age: 5 months.Examine the time: on JIUYUE 19th, 2011; Use Chinese medicine composition of the present invention, oral medicine, one day twice, in sooner or later taking half an hour after meal, medicinal liquid drip washing affected part, once a day; Use the symptom of the pain of itching on the same day, skin focus place obviously to improve; Use 5 days skin lesion (festering) positions to be clearly better, dermatitis, pimple etc. are controlled; Use 12 days skin lesion (festering) positions to heal completely, dermatitis, pimple disappear most; Use 18 days, dermatitis, pimple disappear completely, recover; It singly takes medicine rear suggestion and consolidates 5 days, and drug withdrawal is so far without recurrence, appearance without any side effects between the operating period.
In order to verify the effect of Chinese medicine composition of the present invention, we have carried out the experiment (embodiment 5) of medicine, and accurately data have been carried out to statistics and mathematical analysis.Specific experiment result is as following table:
Table 1:
Through clinical trial, prove, Chinese medicine composition of the present invention is on treatment psoriasis, and effective percentage is 96.7%, and cure rate is more than 93.3%, and than external application Chinese medicine lotion, effective percentage is high by 30%, and cure rate is high by 60%, and than oral Chinese medicine medicament, effective percentage is high by 23.4%, and cure rate is high by 40%; Use Chinese medicine composition of the present invention, can effectively alleviate the pruritus symptom being caused by psoriasis, alleviate fast safely patient's misery, and relapse rate be low, in clinical, not occurring a routine side effect case, is the psoriatic Chinese medicine composition of a kind of safer effective treatment.

Claims (1)

1. a preparation method for the treatment of psoriatic Chinese medicine composition, is characterized in that, takes off the raw material of stating weight proportion: 4.5 grams of Herba Schizonepetae, 4.5 grams of Radix Saposhnikoviaes, 3 grams, Pericarpium Zanthoxyli, 3 grams of Radix Gentianae, 3 grams of Periostracum Cicadaes, 4.5 grams of Cortex Dictamni, 9 grams of the Fructus Kochiae, 9 grams of Semen Coiciss, 9 grams of Zaocyss, 6 grams of Cortex Moutans, 6 grams of Radix Ophiopogonis, 6 grams of Radix Paeoniae Rubra, 6 grams of Fructus Forsythiaes, 9 grams of Radix Salviae Miltiorrhizaes, 9 grams of Herba Taraxacis, 4 grams, Semen Persicae, 3 grams of Cortex Phellodendris, 9 grams of Rhizoma Polygoni Cuspidati;
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Ophiopogonis, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Herba Taraxaci, Semen Persicae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 15 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 20 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 2000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is standby.
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CN103877166A (en) * 2014-01-16 2014-06-25 王雅冬 Medicine composition for treating psoriasis
CN105434793A (en) * 2016-01-14 2016-03-30 王宗山 Composition for treating psoriasis pustulose and preparation method for composition
CN106177639A (en) * 2016-09-26 2016-12-07 四川聚豪生物科技有限公司 One treats psoriatic Chinese medicine composition and preparation method thereof
CN106309626A (en) * 2016-11-11 2017-01-11 成都悦伦商贸有限公司 Traditional Chinese medicine formula for eliminating skin erythema and scales

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CN102416117A (en) * 2011-11-29 2012-04-18 王莲芬 Chinese patent medicine for treating psoriasis
CN102512617A (en) * 2011-12-22 2012-06-27 蔡艳梅 Chinese herbal preparation for treating psoriasis

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102416117A (en) * 2011-11-29 2012-04-18 王莲芬 Chinese patent medicine for treating psoriasis
CN102512617A (en) * 2011-12-22 2012-06-27 蔡艳梅 Chinese herbal preparation for treating psoriasis

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