CN103055200B - Chinese medicinal herb composition for treating wind-heat type psoriasis and preparation method thereof - Google Patents

Chinese medicinal herb composition for treating wind-heat type psoriasis and preparation method thereof Download PDF

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CN103055200B
CN103055200B CN201310017194.1A CN201310017194A CN103055200B CN 103055200 B CN103055200 B CN 103055200B CN 201310017194 A CN201310017194 A CN 201310017194A CN 103055200 B CN103055200 B CN 103055200B
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孟桂梅
刘风华
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HAIMEN JIANGHAI CONSTRUCTION INVESTMENT CO., LTD.
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孟桂梅
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Abstract

The invention discloses a Chinese medicinal herb composition for treating wind-heat type psoriasis and a preparation method thereof, wherein the Chinese medicinal herb composition mainly comprises herba schizonepetae, radices sileris, pepper, radix gentianae, cicada slough, cortex dictamni, fructus kochiae, semen coicis, zaocys dhumnade, moutan bark, radix bupleuri, red peony root, fructus forsythiae, salviae miltiorrhizae, golden cypress and polygonum cuspidatum; the Chinese medicinal herb composition provided by the invention is capable of effectively relieving the rash symptoms caused by the wind-heat type psoriasis and has the effects of relieving itching and stopping pain, thereby achieving a good treatment effect on the wind-heat type psoriasis; and the Chinese medicinal herb composition is safe, effective, free of any side-effect, and suitable for treating the wind-heat type psoriasis.

Description

One is treated psoriatic Chinese medicine composition of anemopyretic and preparation method thereof
Technical field
The invention discloses a kind of Chinese medicine composition, especially treat psoriatic Chinese medicine composition of anemopyretic and preparation method thereof.Belong to Chinese medicine field.
Background technology
Psoriasis, is commonly called as " psoriasis ", and Chinese medicine is referred to as " white Mange ", has again the name of disease such as " psoriasis ", " chronic eczema ", is a kind of common chronic inflammatory disease dermatoses.It belongs to the disease of polygenic inheritance, can be by multiple motivating factor, as wound, infection, medicine etc. all may bring out this disease in susceptible individual.Typical cutaneous manifestations is the red speckle that boundary clearly has silvery white squama.The lighter can show as the patella ulnaris position speckle of several silver coin sizes, and severe one also can be got involved by whole skin.Its physiological pathology mechanism is mainly the abnormal and immune activation of epidermal hyperplasia differentiation.
According to clinical manifestation difference, psoriasis is divided into four types: 1. psoriasis vulgaris is a most common clinical type.The skin lesion initial stage is red pimple or maculopapule, and foxtail millet grain, to Semen phaseoli radiati size, can expand gradually and be fused into red patch later, and boundary is clear, and substrate infiltrates obviously, and skin lesion surface is covered with multilamellar silvery white squama, easily strikes off.Remove the shinny thin film of the visible one deck pale red of surperficial squama, then strike off thin film, occur the sieve little petechia of shape, be called " petechial hemorrhage phenomenon ".White squama, shinny thin film and petechial hemorrhage are the Clinical symptoms of primary disease; 2. psoriasis pustulosa, more rare clinically, account for psoriatic's 0.77%.Generally can be divided into 2 kinds, general property pustule type and Pasfulosis palmaris et plantaris type.General property pustule type is everlasting that malpractice, medicine for external use stimulate or Hormone Withdrawal subtracts morbidity under the inspiring of the factor such as too fast.Acute onset, skin lesion many on the basic lesions of psoriasis vulgaris or around there is the large yellow shallow pimple of foxtail millet grain, with extremity bend side and gauffer position common.There is intensive pustule in the visible whole body of severe patient, pustule is fused into pus lake, and the rubescent swelling of whole skin can be with heating, arthralgia, general malaise etc.Pasfulosis palmaris et plantaris type skin lesion is detected in palm sole of the foot portion, occurs the intensive large pimple of foxtail millet grain on erythema basis, and bleb wall is difficult for breaking, 2 weeks dry and hard crusts of left and right bleb, decortication.Pustule Chang Fanfu occurs, and skin lesion can gradually diffuse to palm toe dorsal part towards periphery; 3., outside patient's desilver bits disease damage evil, also can there is symptoms of rheumatoid arthritis, incidence rate approximately 6.8% in psoriasis arthropathica.Its joint symptom and skin symptom increase the weight of simultaneously or alleviate.After majority of cases is often secondary to psoriasis, or with psoriasis pustulosa or erythrodermic psoriasis and see.Pathological changes can be invaded big or small joint, but with little joints such as hands, wrist and foots, refers to that especially sole of the foot end joint is common.These joint congestion and swelling pains, stiff even amyotrophy; 4. Folium Styracis Suberifoliae psoriasis pustulosa, claims again psoriasis exfoliative dermatitis, accounts for psoriatic's 1%.The clinical state of an illness is heavier, how by psoriasis vulgaris at the phase of carrying out medicine for external use stimulation or malpractice and cause.Clinical manifestation is exfoliative dermatitis, and common whole skin fills the air flushing, swelling, and a large amount of bran defurfurations, palm toe keratinization, first thickens even and comes off.Now the feature of psoriasis vulgaris often disappears, but more, has as seen the skin lesion of small pieces psoriasis vulgaris.Patient is often with symptoms such as heating, fear of cold, headache discomforts, and whole body superficial lymph is tied enlargement.
The psoriasis course of disease is long, easily outbreak repeatedly, sustainable more than 10 years or decades.Most of patient increases the weight of or recur winter, and spring and summer alleviates or disappears season.Generally be divided into for three phases: 1. carry out the phase: newly rash constantly occurs, old rash constantly expands, and skin lesion color is scarlet, infiltrate obviously, squama is thick long-pending, and acute pruritus, can have isomorphic response; 2. resting stage: the state of an illness remains static, occurs without new rash substantially, and former erythra also loses and disappears; 3. catagen: erythra infiltrates attenuation, and color is thin out, squama reduces.Erythra starts to dwindle, and occurs that light color is dizzy, finally leaves over depigmentation macule or pigmentation spots around.Also visible skin lesion, from central clearing, is polygon change or petal sample and changes.
Anemopyretic psoriasis main manifestations is disease onset or falls ill soon, erythra development rapidly, red pimple or erythema are distributed in trunk, extremity and even whole body, and skin lesion squama has petechial hemorrhage after scraping stripping, can have occur together heat, the whole body of pruritus uncomfortable, the symptoms such as thirsty, dry pharynx, pharyngalgia, red tongue, yellow and thin fur, floating pulse, therefore Chinese traditional treatment this type psoriasis should be with clearing away heat and cooling blood, and dispelling wind to relieve the exterior syndrome is main.
Because psoriasis is a kind of chronic disease, and it is wider to involve crowd, and the life impact that it causes patient is very large.Pruritus, squama and visible speckle are puzzlement patient's subject matter.
The traditional Chinese medical science adopts and follows the method for levying medical science, and the dialectical differential diagnosis of diseases of psoriatic clinical manifestation and the traditional Chinese medical science is combined.
In the method for existing Psoriasis Treated by TCM, Chinese invention patent application CN02134397.7 discloses a kind of " one is treated psoriatic liquid medicine of exterior coating " by name on January 8th, 2003, dried Alumen and the vaseline of its charcoal powder by alligator oil, Oleum Arachidis hypogaeae semen, mistake 100 mesh sieves, mistake 100 mesh sieves form, prepare burden expensive and be not easy to obtain, preparation method complexity, and it is external-applied ointment, cannot reach the object of radical cure.
Summary of the invention
For the present situation of existing treatment anemopyretic psoriasis deficiency, one of object of the present invention is to provide one to treat the psoriatic Chinese medicine composition of anemopyretic, there is feature easy to operate, instant effect, and it adopts comparatively common in the localities Chinese crude drug as raw material, with low cost, alleviate patient's burden economically.
Another object of the present invention is just to provide the psoriatic preparation method of above-mentioned treatment anemopyretic.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
One is treated the psoriatic Chinese medicine composition of anemopyretic, and preferred proportioning is taken off the primary raw material of stating weight proportion and is prepared from: Herba Schizonepetae 4.5-9 part, Radix Saposhnikoviae 4.5-9 part, Pericarpium Zanthoxyli 3-6 part, Radix Gentianae 3-6 part, Periostracum Cicadae 3-6 part, Cortex Dictamni 4.5-9 part, Fructus Kochiae 9-15 part, Semen Coicis 9-30 part is (preferred, Semen Coicis 9.5-29.5 part), Zaocys 9-12 part, Cortex Moutan 6-12 part, Radix Bupleuri 10-18 part, Radix Paeoniae Rubra 6-12 part, Fructus Forsythiae 6-15 part, Radix Salviae Miltiorrhizae 9-15 part, Cortex Phellodendri 3-12 part, Rhizoma Polygoni Cuspidati 9-15 part.
One is treated the psoriatic Chinese medicine composition of anemopyretic, and more preferably proportioning is taken off the primary raw material of stating weight proportion and is prepared from: Herba Schizonepetae 5-8 part, Radix Saposhnikoviae 5-8 part, Pericarpium Zanthoxyli 3.5-5 part, Radix Gentianae 3.5-5 part, Periostracum Cicadae 3.5-5 part, Cortex Dictamni 5-8 part, Fructus Kochiae 10-14 part, Semen Coicis 12-25 part, Zaocys 9.5-11 part, Cortex Moutan 7-11 part, Radix Bupleuri 12-16 part, Radix Paeoniae Rubra 7-11 part, Fructus Forsythiae 8-12 part, Radix Salviae Miltiorrhizae 10-13 part, Cortex Phellodendri 4-10 part, Rhizoma Polygoni Cuspidati 10-14 part.
One is treated the psoriatic Chinese medicine composition of anemopyretic, and best proportioning is taken off the primary raw material of stating weight proportion and is prepared from: 6 parts of Herba Schizonepetae, 7 parts of Radix Saposhnikoviaes, 4.5 parts, Pericarpium Zanthoxyli, 4 parts of Radix Gentianae, 4 parts of Periostracum Cicadaes, 7 parts of Cortex Dictamni, 11 parts of the Fructus Kochiae, 22 parts of Semen Coiciss, 10 parts of Zaocyss, 8 parts of Cortex Moutans, 14 parts of Radix Bupleuri, 8 parts of Radix Paeoniae Rubra, 10 parts of Fructus Forsythiaes, 12 parts of Radix Salviae Miltiorrhizaes, 6 parts of Cortex Phellodendris, 12 parts of Rhizoma Polygoni Cuspidati.
One is treated the psoriatic Chinese medicine composition preparation method of anemopyretic, and preparation process is as follows:
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in the interior cold water soak 15-35 minute that uses of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 20-50 minute at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 20-45 minute at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 2000-6000 milliliter again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use.
Above-mentioned preparation method, 1. step uses cold water soak 15-35 minute (preferably 20-30 minute, is more preferably 25 minutes).
Above-mentioned preparation method, step 1. 20-50 at a simmer minute (preferably 25-40 minute, is more preferably 30 minutes).
Above-mentioned preparation method, 2. step turns 20-45 at a simmer minute (preferably 25-35 minute, is more preferably 30 minutes).
Above-mentioned preparation method, 3. step is blended into the water of 2000-6000 milliliter (preferably 3000-5500, is more preferably 4000 milliliters) again.
Using method: for making the present invention reach optimum therapeuticing effect, Chinese medicine composition of the present invention, the medicinal liquid of twice mixing is divided into 2 parts, in sooner or later taking half an hour after meal; The medicinal liquid of decocting for the third time, once a day, drip washing affected part.
This Chinese medicine composition is remarkable to the psoriatic effect of anemopyretic, not only has effect antipruritic, that peeling rash etc. is controlled table disease, can also fundamentally thoroughly treat anemopyretic psoriasis, and can be for the different reason determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs of anemopyretic psoriasis.Local common medical material for multiselect of the present invention, cheap, alleviate patient's financial burden.
One is treated the psoriatic Chinese medicine composition of anemopyretic, and the pharmacological effect of each crude drug is respectively:
Herba Schizonepetae: acrid in the mouth, micro-hardship, slightly warm in nature.There is the loose wind that induces sweat, rash, the skin ulcer that disappears, effect of hemostasis, for furuncle, cold, fever.
Radix Saposhnikoviae: acrid in the mouth, sweet, slightly warm in nature.For inducing sweat, dispel the wind medicine, there is expelling pathogenic wind from the body surface, removing dampness to relieve pain, antipruritic effect, for affection of exogenous wind-cold, rheumatic arthralgia, rubella pruritus.
Pericarpium Zanthoxyli: acrid in the mouth, warm in nature.There is warming middle-JIAO to relieve pain, effect of killing parasites for relieving itching, for coldness and pain in the epigastrium, vomiting is had loose bowels, external treatment eczema pruritus.
Radix Gentianae: bitter in the mouth, cold in nature.There is heat clearing and damp drying, effect of clearing away heat-fire, for damp invasion of lower energizer, headache conjunctival congestion, Hiccough and deaf.
Periostracum Cicadae: sweet in the mouth, cold in nature.There is loose wind heat extraction, effect of rash, for anemopyretic cold, pharyngalgia, rubella pruritus, convulsion with spasms.
Cortex Dictamni: bitter in the mouth, salty, cold in nature.There is heat clearing and damp drying, dispelling wind for relieving itching, effect of removing toxic substances, for rubella, eczema, scabies due to wind heat noxious dampness.
The Fructus Kochiae: acrid in the mouth, hardship, cold in nature.There is clearing away heat-damp and promoting diuresis, effect of dispelling wind for relieving itching, for rubella, eczema, skin pruritus.
Semen Coicis: sweet in the mouth, light, cool in nature.There is spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, for edema, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen.
Zaocys: sweet in the mouth, property is flat.Dispel the wind, dredging collateral, effect of relieving convulsion, for rheumatoid arthritis stubborn, leprosy scabies, malignant boil.
Cortex Moutan: bitter in the mouth, pungent, cold in nature.There is clearing away heat and cooling blood, effect of promoting blood circulation to remove blood stasis, for deficiency of YIN osteopyrexia and fever, carbuncle sore tumefacting virus, rheumatism pyretic arthralgia.
Radix Bupleuri: bitter in the mouth, cold nature.Have and show in solution, soothing the liver, effect of yang invigorating, for cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium.
Radix Paeoniae Rubra: bitter in the mouth, cold nature.There is clearing away heat and cooling blood, effect of eliminating stasis to stop pain, for maculae caused by violent heat pathogen, hypochondriac pain due to stagnation of liverQI.
Fructus Forsythiae: bitter in the mouth, cold nature.There is heat-clearing and toxic substances removing, the loose swollen effect of the knot that disappears, for anemopyretic cold, heating, macule, carbuncle pyogenic infections from tumour or sore.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.Invigorate blood circulation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, effect of the relieving restlessness that clears away heart-fire, for pyretic arthralgia pain, skin infection swells and ache.
Cortex Phellodendri: bitter in the mouth, cold in nature.There is heat clearing and damp drying, effect of eliminating fire and detoxication, for hectic fever due to YIN-deficiency consumptive fever, sore swollen toxin, eczema pruritus.
Rhizoma Polygoni Cuspidati: mildly bitter flavor, cold nature.There is heat-clearing and toxic substances removing, expelling wind and removing dampness, effect of dissipating blood stasis analgesic therapy, for arthralgia, damp and hot, too fat to move sore.
Chinese medicine composition of the present invention is based on the psoriatic principle of traditional Chinese medical herbal treatment anemopyretic.The Chinese medicinal material of selecting has toxin expelling, removing heat from blood, and the hot effect of dispelling, can contain the speed of distributing of anemopyretic psoriasis erythra effectively, and cheap, life-time service also can not cause patient's financial burden, is the comparatively desirable medicine for the treatment of anemopyretic psoriasis.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1
4.5 grams of Herba Schizonepetae, 4.5 grams of Radix Saposhnikoviaes, 3 grams, Pericarpium Zanthoxyli, 3 grams of Radix Gentianae, 3 grams of Periostracum Cicadaes, 4.5 grams of Cortex Dictamni, 9 grams of the Fructus Kochiae, 9 grams of Semen Coiciss, 9 grams of Zaocyss, 6 grams of Cortex Moutans, 10 grams of Radix Bupleuri, 6 grams of Radix Paeoniae Rubra, 6 grams of Fructus Forsythiaes, 9 grams of Radix Salviae Miltiorrhizaes, 3 grams of Cortex Phellodendris, 9 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 15 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 20 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 2000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use.
embodiment 2
5 grams of Herba Schizonepetae, 5 grams of Radix Saposhnikoviaes, 3.5 grams, Pericarpium Zanthoxyli, 3.5 grams of Radix Gentianae, 3.5 grams of Periostracum Cicadaes, 5 grams of Cortex Dictamni, 10 grams of the Fructus Kochiae, 12 grams of Semen Coiciss, 9.5 grams of Zaocyss, 7 grams of Cortex Moutans, 12 grams of Radix Bupleuri, 7 grams of Radix Paeoniae Rubra, 8 grams of Fructus Forsythiaes, 10 grams of Radix Salviae Miltiorrhizaes, 4 grams of Cortex Phellodendris, 10 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 20 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 25 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 25 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 3000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use.
embodiment 3
8 grams of Herba Schizonepetae, 8 grams of Radix Saposhnikoviaes, 5 grams, Pericarpium Zanthoxyli, 5 grams of Radix Gentianae, 5 grams of Periostracum Cicadaes, 8 grams of Cortex Dictamni, 14 grams of the Fructus Kochiae, 25 grams of Semen Coiciss, 11 grams of Zaocyss, 11 grams of Cortex Moutans, 16 grams of Radix Bupleuri, 11 grams of Radix Paeoniae Rubra, 12 grams of Fructus Forsythiaes, 13 grams of Radix Salviae Miltiorrhizaes, 10 grams of Cortex Phellodendris, 14 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 30 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 40 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 5500 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use.
embodiment 4
9 grams of Herba Schizonepetae, 9 grams of Radix Saposhnikoviaes, 6 grams, Pericarpium Zanthoxyli, 6 grams of Radix Gentianae, 6 grams of Periostracum Cicadaes, 9 grams of Cortex Dictamni, 15 grams of the Fructus Kochiae, 30 grams of Semen Coiciss, 12 grams of Zaocyss, 12 grams of Cortex Moutans, 18 grams of Radix Bupleuri, 12 grams of Radix Paeoniae Rubra, 15 grams of Fructus Forsythiaes, 15 grams of Radix Salviae Miltiorrhizaes, 12 grams of Cortex Phellodendris, 15 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 35 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 50 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 45 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 6000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use.
embodiment 5
6 grams of Herba Schizonepetae, 7 grams of Radix Saposhnikoviaes, 4.5 grams, Pericarpium Zanthoxyli, 4 grams of Radix Gentianae, 4 grams of Periostracum Cicadaes, 7 grams of Cortex Dictamni, 11 grams of the Fructus Kochiae, 22 grams of Semen Coiciss, 10 grams of Zaocyss, 8 grams of Cortex Moutans, 14 grams of Radix Bupleuri, 8 grams of Radix Paeoniae Rubra, 10 grams of Fructus Forsythiaes, 12 grams of Radix Salviae Miltiorrhizaes, 6 grams of Cortex Phellodendris, 12 grams of Rhizoma Polygoni Cuspidati.
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in interior cold water soak 25 minutes of using of container of non iron, and cold water did not have 2 cun of medical materials to be advisable, be fried open with high heat, turn 30 minutes at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 30 minutes at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use;
3. recrement is blended into the water of 4000 milliliters again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use.
Using method: for making the present invention reach optimum therapeuticing effect, Chinese medicine composition of the present invention, the medicinal liquid of twice mixing is divided into 2 parts, in sooner or later taking half an hour after meal; The medicinal liquid of decocting for the third time, once a day, drip washing affected part.
model case one
Open XX, man, 24 years old, Qingdao of Shandong province Laoshan District.Symptom: originally patient's extremity have played some red rash, painless gargalesthesia was felt at that time, but in two days, erythra increases rapidly, and with dry squama, and pruritus is hard to bear, and the whole body is uncomfortable, and health heating is often thirsty.Be anemopyretic psoriasis through hospital diagnosis.Sick age: 1 month.Examine the time: on 03 27th, 2011; Use Chinese medicine composition of the present invention, oral medicine, one day twice, in sooner or later taking half an hour after meal, medicinal liquid drip washing affected part, once a day; Used just felt that pruritus alleviated the same day; Use 5 days, erythra area and squama start to reduce, and pruritus disappears; Use 12 days, various ill symptomses disappear, and recover; After use again Chinese medicine composition of the present invention to consolidate 5 days, drug withdrawal so far without recurrence.
model case two
Lee XX, man, 32 years old, villages and small towns were opened in In Shandong Weihai.Near symptom: patient falls ill and just occurs that small size skin is general red shank, with red goose pimples, after in several days, diffuse to rapidly extremity, and surface is with multilamellar silvery white flakey scurf, the abnormal pruritus in affected part, local with skin lesion (festering) phenomenon, be diagnosed as anemopyretic psoriasis through hospital.Sick age: 2 months.Examine the time: on August 7th, 2011; Use Chinese medicine composition of the present invention, oral medicine, one day twice, in sooner or later taking half an hour after meal, medicinal liquid drip washing affected part, once a day; Use skin itch symptom on the same day alleviates; Use 7 days, skin lesion (festering) position is clearly better, and dermatitis, pimple etc. are controlled; Use 13 days, skin lesion (festering) position starts to scab, and does not occur new skin lesion situation again, and skin pruritus symptom disappears; Use 22 days, squama, pimples etc. disappear completely, recover; Continue to use Chinese medicine composition of the present invention to consolidate 7 days, drug withdrawal is so far without recurrence, and the symptom that has no side effect between the operating period occurs.
In order to verify the effect of Chinese medicine composition of the present invention, we have carried out the experiment (embodiment 5) of medicine, and accurately data have been carried out to statistics and mathematical analysis.Specific experiment result is as following table:
Figure 846554DEST_PATH_IMAGE002
Prove through clinical trial, Chinese medicine composition of the present invention is on treatment anemopyretic psoriasis, and effective percentage is 97.5%, and cure rate is more than 90.8%, than external application Chinese medicine lotion, effective percentage is high by 22.5%, and cure rate is high by 49.1%, than oral Chinese medicine medicament, effective percentage is high by 12.5%, and cure rate is high by 24.1%; Use Chinese medicine composition of the present invention, can effectively alleviate the pruritus symptom being caused by anemopyretic psoriasis, contain fast and effectively the divergence speed of erythra, alleviate patient's misery, and relapse rate is low, in clinical, not occurring a routine side effect case, is the psoriatic Chinese medicine composition of a kind of safer effective treatment anemopyretic.

Claims (11)

1. a preparation method for the treatment of the psoriatic Chinese medicine composition of anemopyretic, is characterized in that, takes off the raw material of stating weight proportion and is prepared from: Herba Schizonepetae 4.5-9 part, Radix Saposhnikoviae 4.5-9 part, Pericarpium Zanthoxyli 3-6 part, Radix Gentianae 3-6 part, Periostracum Cicadae 3-6 part, Cortex Dictamni 4.5-9 part, Fructus Kochiae 9-15 part, Semen Coicis 9-30 part, Zaocys 9-12 part, Cortex Moutan 6-12 part, Radix Bupleuri 10-18 part, Radix Paeoniae Rubra 6-12 part, Fructus Forsythiae 6-15 part, Radix Salviae Miltiorrhizae 9-15 part, Cortex Phellodendri 3-12 part, Rhizoma Polygoni Cuspidati 9-15 part; Step is as follows:
1. by Herba Schizonepetae, Radix Saposhnikoviae, Pericarpium Zanthoxyli, Radix Gentianae, Periostracum Cicadae, Cortex Dictamni, the Fructus Kochiae, Semen Coicis, Zaocys, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Rubra, Fructus Forsythiae, Radix Salviae Miltiorrhizae, Cortex Phellodendri, Rhizoma Polygoni Cuspidati is placed in the interior cold water soak 15-35 minute that uses of container of non iron, and cold water did not have 2 cun of medical materials, be fried open with high heat, turn 20-50 minute at a simmer, leach medicinal liquid;
2. recrement adds water, and intense fire is fried open, and turns 20-45 minute at a simmer, leaches medicinal liquid, twice medicinal liquid mixing for standby use; The medicinal liquid mixing is divided into 2 parts, in sooner or later taking half an hour after meal;
3. recrement is blended into the water of 2000-6000 milliliter again, and intense fire is boiled, leaches medicinal residues, and medicinal liquid is for subsequent use, the medicinal liquid that this step obtains, once a day, drip washing affected part.
2. according to preparation method claimed in claim 1, it is characterized in that, each crude drug is as follows: Herba Schizonepetae 5-8 part, Radix Saposhnikoviae 5-8 part, Pericarpium Zanthoxyli 3.5-5 part, Radix Gentianae 3.5-5 part, Periostracum Cicadae 3.5-5 part, Cortex Dictamni 5-8 part, Fructus Kochiae 10-14 part, Semen Coicis 12-25 part, Zaocys 9.5-11 part, Cortex Moutan 7-11 part, Radix Bupleuri 12-16 part, Radix Paeoniae Rubra 7-11 part, Fructus Forsythiae 8-12 part, Radix Salviae Miltiorrhizae 10-13 part, Cortex Phellodendri 4-10 part, Rhizoma Polygoni Cuspidati 10-14 part.
3. according to preparation method claimed in claim 1, it is characterized in that, each crude drug is as follows: 6 parts of Herba Schizonepetae, 7 parts of Radix Saposhnikoviaes, 4.5 parts, Pericarpium Zanthoxyli, 4 parts of Radix Gentianae, 4 parts of Periostracum Cicadaes, 7 parts of Cortex Dictamni, 11 parts of the Fructus Kochiae, 22 parts of Semen Coiciss, 10 parts of Zaocyss, 8 parts of Cortex Moutans, 14 parts of Radix Bupleuri, 8 parts of Radix Paeoniae Rubra, 10 parts of Fructus Forsythiaes, 12 parts of Radix Salviae Miltiorrhizaes, 6 parts of Cortex Phellodendris, 12 parts of Rhizoma Polygoni Cuspidati.
4. preparation method according to claim 1, is characterized in that, 1. step uses cold water soak 20-30 minute.
5. preparation method according to claim 4, is characterized in that, 1. step uses cold water soak 25 minutes.
6. preparation method according to claim 1, is characterized in that, step is 25-40 minute at a simmer 1..
7. preparation method according to claim 6, is characterized in that, step 1. 30 minutes at a simmer.
8. preparation method according to claim 1, is characterized in that, 2. step turns 25-35 minute at a simmer.
9. preparation method according to claim 8, is characterized in that, 2. step turns 30 minutes at a simmer.
10. preparation method according to claim 1, is characterized in that, 3. step is blended into the water of 3000-5500 milliliter again.
11. preparation methoies according to claim 10, is characterized in that, 3. step is blended into the water of 4000 milliliters again.
CN201310017194.1A 2013-01-17 2013-01-17 Chinese medicinal herb composition for treating wind-heat type psoriasis and preparation method thereof Expired - Fee Related CN103055200B (en)

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CN103393772A (en) * 2013-08-22 2013-11-20 王爱枝 Medicine for treating psoriasis, and preparation method of medicine
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CN102406866A (en) * 2011-11-16 2012-04-11 王莲芬 Chinese medicinal composition for treating psoriasis
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