(3) summary of the invention
The present invention, in order to make up the deficiencies in the prior art, provides a kind of Chinese medicine for oral administration of preventing and treating hemolytic disease of newborn simple, evident in efficacy of preparing.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine for oral administration of preventing and treating hemolytic disease of newborn, it is characterized by, make pill by the raw material of following parts by weight: Herba Leonuri 450-550 part, Radix Angelicae Sinensis 100-200 part, Radix Paeoniae Alba 100-200 part, Rhizoma Chuanxiong 100-200 part, Radix Aucklandiae 10-15 part, Flos Hemerocallis 15-30 part, Arillus Longan 10-15 part, Fructus Crataegi 3-10 part, Herba Artemisiae Scopariae 10-15 part.
Its preferred weight proportion is:
500 parts of Herba Leonuris, 150 parts of Radix Angelicae Sinensis, 150 parts of the Radix Paeoniae Albas, 150 parts of Rhizoma Chuanxiongs, 12 parts of the Radix Aucklandiae, 22 parts of pin dishes, 12 parts of Arillus Longan, 6 parts of Fructus Crataegis, 12 parts of Herba Artemisiae Scopariae.
Pill of the present invention be by Semen setariae by with the weight ratio maceration of raw material total amount 1:25-40 after, be placed in pulverize, the Chinese medicine powder of mix homogeneously rocks and holds, dries and make.
The pharmaceutical characteristic of each raw material that the present invention adopts is:
Herba Leonuri: promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing.Cure mainly menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection;
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Cure mainly all diseases of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down;
The Radix Paeoniae Alba: nourish blood and seek, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver.Cure mainly blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, stimulates the menstrual flow, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and has a headache dizzy;
Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.Cure mainly menoxenia, amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal , mass in the abdomen lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia, traumatic injury, ulcer sores;
The Radix Aucklandiae: promoting the circulation of QI to relieve pain, intestinal stasis relieving in tune.Cure mainly fullness and distention in the chest and hypochondrium, abdominal distention, vomiting is had loose bowels, heavy after dysentery;
Semen setariae: and in, kidney tonifying, heat extraction, removing toxic substances.Cure mainly taste deficiency-heat, regurgitation vomiting, abdominal distention lack of appetite, quenches one's thirst, dysentery, burn and scald;
Flos Hemerocallis: dampness removing heat, resolving depression, removing heat from blood.Cure mainly oliguria with reddish urine, jaundice, chest and diaphragm dysphoria with smothery sensation, pacify and sleep night less, bleeding hemorrhoids, carbuncle sore;
Arillus Longan, has another name called Arillus Longan: reinforcing the heart spleen, replenishing QI and blood, calms the nerves.Cure mainly asthenia, palpitation with fear, palpitation with a distress feeling, insomnia, forgetful, blood deficiency and yellow complexion, menoxenia, metrorrhagia;
Fructus Crataegi: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis.Cure mainly eating accumulation, abdominal distention, dysentery, dysmenorrhea due to blood stasis, amenorrhea, puerperal abdonimal pain, hernia or painful and swollen testis, hyperlipidemia;
Herba Artemisiae Scopariae: clearing away heat-damp and promoting diuresis, jaundice eliminating.Jaundice, dysuria, eczema pruritus.
The present invention invigorates blood circulation to enrich blood, menstruction regulating and pain relieving, activating QI to alleviate the depression be as the rule for the treatment of, multi-medicament has combined synergism, and hemolytic disease of newborn is had to significant preventive and therapeutic effect.
Clinical observation:
(1) clinical data
The inventor in 2006 so far, carries out clinical observation treatment to 93 routine hemolytic disease of newborn patients.
(2) Therapeutic Method
Oral, three times on the one, each 8-12g, one after each meal.According to conditions of patients weight calculate treatment time, patients with mild take 2 months effective, severe case serve on 6 months effective.
(3) curative effect determinate standard
Criterion of therapeutical effect is with reference to relevant criterion of therapeutical effect in " disease of tcm judgement criterion of therapeutical effect ".
Cure: clinical symptoms all disappears, and lab testing is normal.
Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation approaches normal level.
Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, sign is improved.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
(4) clinical effectiveness
Clinical cure 70 examples (75.27%), effective 14 examples (15.05%), effective 7 examples (7.53%), invalid 2 examples (2.15%), total effective rate is 97.85%.
The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, safe, and production cost is low, is conducive to sufferer and alleviates in time condition of illness.
(4) specific embodiment
Embodiment 1:
Prescription: Herba Leonuri 450g, Radix Angelicae Sinensis 100g, Radix Paeoniae Alba 100g, Rhizoma Chuanxiong 100g, Radix Aucklandiae 10g, Flos Hemerocallis 15g, Arillus Longan 10g, Fructus Crataegi 3g, Herba Artemisiae Scopariae 10g.
Preparation method: above-mentioned crude drug is total to 798g and is ground into fine powder completely, cross dusting cover for subsequent use, choose etc. that fresh Semen setariae 30g soaks deliquescing and for subsequent use when not rotten, add a small amount of distilled water after humidity, to sneak into Semen setariae for subsequent use a little ready Chinese medicine powder, rock vessel and make medicated powder hold into solid pill layer by layer, dry rear for subsequent use.The about 826g of dried pill weight left and right.
Application process: point morning, noon and afternoon three times are oral, each 8-12g.
Embodiment 2:
Prescription: Herba Leonuri 500g, Radix Angelicae Sinensis 150g, Radix Paeoniae Alba 150g, Rhizoma Chuanxiong 150g, Radix Aucklandiae 12g, pin dish 22g, Arillus Longan 12g, Fructus Crataegi 6g, Herba Artemisiae Scopariae 12g.
Preparation method: above-mentioned crude drug is total to 1014g and is ground into fine powder completely, cross dusting cover for subsequent use, choose etc. that fresh Semen setariae 30g soaks deliquescing and for subsequent use when not rotten, add a small amount of distilled water after humidity, to sneak into Semen setariae for subsequent use a little ready Chinese medicine powder, rock vessel and make medicated powder hold into solid pill layer by layer, dry rear for subsequent use.The about 1041g of dried pill weight left and right.
Application process: point morning, noon and afternoon three times are oral, each 8-12g.
Embodiment 3:
Prescription: Herba Leonuri 550g, Radix Angelicae Sinensis 200g, Radix Paeoniae Alba 200g, Rhizoma Chuanxiong 200g, Radix Aucklandiae 15g, Flos Hemerocallis 30g, Arillus Longan 15g, Fructus Crataegi 10g, Herba Artemisiae Scopariae 15g.
Preparation method: above-mentioned crude drug is total to 1185g and is ground into fine powder completely, cross dusting cover for subsequent use, choose etc. that fresh Semen setariae 30g soaks deliquescing and for subsequent use when not rotten, add a small amount of distilled water after humidity, to sneak into Semen setariae for subsequent use a little ready Chinese medicine powder, rock vessel and make medicated powder hold into solid pill layer by layer, dry rear for subsequent use.The about 1210g of dried pill weight left and right.
Application process: point morning, noon and afternoon three times are oral, each 8-12g.