CN104306898A - Orally taken traditional Chinese medicine for treating hysteromyoma - Google Patents
Orally taken traditional Chinese medicine for treating hysteromyoma Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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Abstract
The invention relates to the field of the application of traditional Chinese medicines, and particularly discloses an orally taken traditional Chinese medicine for treating hysteromyoma. The orally taken traditional Chinese medicine for treating the hysteromyoma uses tree peony bark, peach kernels, cassia twigs, poria cocos, radix salviae miltiorrhizae, roots of herbaceous peony, curcuma zedoaria, Chinese angelica, winged euonymus twigs and european verbena herbs as raw materials, and the raw materials are mixed to prepare pills in a certain proportion by weight. The orally taken traditional Chinese medicine is simple to compound, the absorption effect is good, the drug effect lasts for a long time, the evident effect is obvious, side effects are not caused, the safety is high, the production costs are low, and the orally taken traditional Chinese medicine is favor for timely alleviating the symptom of patients.
Description
(1) technical field
The present invention relates to application in TCM field, particularly a kind of Chinese medicine for oral administration for the treatment of hysteromyoma.
(2) background technology
Hysteromyoma, also known as leiomyoma of uterus, is the modal a kind of benign tumors of female sex organs, is also the modal tumor of human body.Many non-evident symptons, are only occasionally found when pelvioscopy, and symptom occurs with muscular tumor position, the speed of growth and Leiomyoma degeneration in close relations, little with muscular tumor how many relations.Clinical symptoms is the most common with change in menstrual cycle characteristics, accounts for 50%.Hypogastric region is laid one's hand on and enclosed mass accounts for main suit's 70%, and minority shows as leucorrhoea grow in quantity, stomachache, the soreness of waist, bearing down, the infertile and secondary anemia of pressure symptom etc., as caused acute abdominal pain when there is torsion of pedicle or other situations, common with multiple myomata.
Compared with in the past, hysteromyoma more and more favored the female middle-aged of 34 years old, did not particularly educate, sexual life imbalance and depressed this three class women of disposition.Gynaecologist is introduced, the concrete reason of hysteromyoma is still not very clear at present, but research surface, hormone secretion is too vigorous, the most common reason causing hysteromyoma, and this three behaviors pattern of women, be cause endocrine regulation, cause the arch-criminal of hormone secretion surplus, this disease drastically influence the physical and mental health of women population.
Although operation is the effective ways of this disease for the treatment of, due to the shortcoming of operation risk, damage and secondary, the trial exploring non-operative treatment comes into one's own day by day.Modern medicine non-operative treatment hysteromyoma, mainly through suppressing the growth of hysteromyoma to antiestrogenic, muscular tumor is even made to reduce, thus alleviate or alleviate muscular tumor related symptoms, but generally can not eliminate and effect a radical cure, often after drug withdrawal, in satellite sex hormone level recovery and have muscular tumor to recur or the possibility of regrowth, and not yet solve problem that is long-term or consolidate curative effect, the safety problem of long-term treatment, the problems such as therapy mechanism.
Primary disease is belonged to “ mass in the abdomen ” ， mass in the abdomen person and calls woman's hypogastric region enclosed mass by the traditional Chinese medical science, tangiblely demonstrate,proves, and has block to scoop, and does not hardly move.The description of You Guan mass in the abdomen, sees " interior through the empty talk of Plain Questions bone " the earliest: " conception vessel for sick, knot seven kinds of hernia in man; woman's leukorrhagia abdominal mass is gathered ", " a Ling Shu Miraculous Pivot or Divine Axis watery distension section " " stony mass of uterus is born in born of the same parents, pathogenic cold invasion in the cervical orifice of the uterus; cervical orifice of uterus is inaccessible, and gas must not lead to, and stagnant blood is when rushing down; only to stay; day is large with benefit, shape as cup, irregular menstrual cycle; be all born in woman, can lead and under.”
The mass in the abdomen origin cause of formation is a lot of, and ancient Chinese medicine doctor all has discussion.Sum up the saying of forefathers to Ming Dynasty Zhang Jingyue, the card of Zhi Chu mass in the abdomen be " by menstrual period, or by puerperal, all internal injury raw food, or have a cold outward, or impairing the liver of being enraged, QI rising in reverse order and blood stays; Or melancholy impairing the spleen, the deficiency of vital energy and stasis; Or fall sick from overwork, gas is weak and not all right, and when always having blood dynamic, remaining blood is unclean, and one is inverse to some extent, then day of being detained is amassed, and gradually to become abdominal mass." exopathogenic factor mostly is being invaded by exogenous pathogen (air-cooled cold-evil invasion, or experience damp, pathogenic heat or damp and hot heresy).Endogenous cause of ill mostly is feelings will internal injury, weakened body resistance, stagnation of phlegm; Other also have operation, fecund, exhaustion due to sexual indulgence etc., all can cause the punching of congestion retardance uterus and appoint, with the passing of time become.Most doctor thinks that " blood stasis " is the pathogenesis key of primary disease.
The main pathogenesis of primary disease is QI-blood circulation imbalance, and zang-fu differentiation dysfunction, for a long time Jie Cheng mass in the abdomen, the main cause of QI-blood circulation imbalance mainly contains the stagnation of QI, cold coagulation, phlegm-damp or damp and hot.
Stagnation of QI person, how because of depression of liver-QI, QI-blood circulation is obstructed, stagnant in a punching uterus, with the passing of time forms caking.Blood stasis person, how because of puerperal in menstrual period, vessels of the uterus is hollow, and remaining blood is most, intemperate sexual intercourse, or exopathogen invasion and attack, so that sluggish QI and blood; Or qi depression to blood stasis; Or blood stagnancy due to deficiency of QI, congestion is detained to rush and is appointed uterus, gradually Ji Cheng Disorder.Phlegm-damp person, then because of insufficiency of the spleen transformation failure of spleen, stop in turbid damp, gathers and form expectorant, and bet is rushed and appointed, retardance collaterals of the uterus, and expectorant blood wins knot mutually, amasss and forms.Damp and hot person, or because of diseases caused by exogenous pathogenic factor, or wetly accumulate heat-transformation, the rich knot of damp and hot congestion is appointed in punching, ties in uterus vessels of the uterus, with the passing of time Cheng Disorder.
Treatment by Chinese herbs hysteromyoma also has many explorations, Ramulus Cinnamomi Poria pill is the classic prescriptions for the treatment of hysteromyoma, modern Chinese medicine preparation is as GONGLIUQING capsule and some are from intending prescription, all try to explore in treatment hysteromyoma, but there is not yet so far by acknowledged, determined curative effect, the Chinese medicine preparation that muscular tumor can be eliminated.
(3) summary of the invention
The present invention, in order to make up the deficiencies in the prior art, provides a kind of Chinese medicine for oral administration preparing treatment hysteromyoma simple, evident in efficacy.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine for oral administration for the treatment of hysteromyoma, it is characterized by, make pill by the raw material of following parts by weight: Cortex Moutan 120-160 part, Semen Persicae 50-90 part, Ramulus Cinnamomi 50-90 part, Poria 180-240 part, Radix Salviae Miltiorrhizae 180-240 part, Radix Paeoniae Rubra 50-90 part, Rhizoma Curcumae 20-60 part, Radix Angelicae Sinensis 50-90 part, Ramulus Euonymi 80-120 part, Herba Verbenae 80-120 part.
The weight proportion of its preferred each raw material is:
Cortex Moutan 140 parts, 70 parts, Semen Persicae, Ramulus Cinnamomi 70 parts, 210 parts, Poria, Radix Salviae Miltiorrhizae 210 parts, Radix Paeoniae Rubra 70 parts, Rhizoma Curcumae 42 parts, Radix Angelicae Sinensis 70 parts, Ramulus Euonymi 105 parts, Herba Verbenae 105 parts.
Described raw material pulverizing is after powder, sieving for standby, Semen setariae is soaked deliquescing and not rotten time for subsequent use, material powder adds water after humidity and is mixed into Semen setariae for subsequent use, and mixed dynamic vessel make raw material powder hold Semen setariae layer by layer to become solid pill, dries for subsequent usely namely to obtain product afterwards.
The weight proportion of described raw material and Semen setariae is 86-130:3.
The pharmaceutical characteristic of above-mentioned each raw material is as follows:
Cortex Moutan: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis.Cure mainly the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, and carbuncle sore tumefacting virus, falls and flutter the pain of injury, beriberoid pyretic arthralgia;
Semen Persicae: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.Cure mainly dysmenorrhea, amenorrhea due to stagnation of blood, the stasis of blood in puerperal stagnant stomachache ， mass in the abdomen lumps, traumatic injury, swelling and pain due to blood stasis, lung abscess, acute appendicitis, dryness of the intestine constipation;
Ramulus Cinnamomi: expelling cold and relieving exterior syndrome, warming the meridian, activates yang.Cure mainly wind and cold to characterize, arthralgia due to cold-dampnes, extreme cold of the limbs, amenorrhea dysmenorrhea ， mass in the abdomen lumps, the thoracic obstruction, cardiopalmus, phlegm retention, dysuria;
Poria: promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, solidifying heart and tranquilizing mind.Cure mainly dysuria, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, to have loose bowels, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine;
Radix Salviae Miltiorrhizae: blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, relieving restlessness is calmed the nerves, removing heat from blood eliminating carbuncle.Cure mainly menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate pain ， lumps in the chest and abdomen, pyretic arthralgia swells and ache, traumatic injury, thermal man's nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore;
Radix Paeoniae Rubra: clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle skin infection, amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia abdominal mass is gathered, injury from falling down;
Rhizoma Curcumae: circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving, cures mainly QI and blood pained, eating accumulation, abdominal distention, amenorrhea due to stagnation of blood, dysmenorrhea ， mass in the abdomen mass in the abdomen, traumatic injury;
Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, moisturizes laxation.Cure mainly all diseases of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, heavy after bloody dysentery, ulcer sores, injury from falling down;
Ramulus Euonymi: removing blood stasis stimulates the menstrual flow, removing toxic substances and promoting subsidence of swelling, parasite killing.Zhu Zhi mass in the abdomen lump, trusted subordinate's pain, amenorrhea, stimulates the menstrual flow, metrorrhagia and metrostaxis, the stagnant stomachache of the stasis of blood in puerperal, retention of lochia, puerperal agalactia, hernia, severe and migratory arthralgia arthralgia pain, skin ulcer swell, traumatic pain, abdominal pain due to worm stagnation, burn and scald, venom, rheumatalgia, dry cough catch a cold;
Herba Verbenae: heat-clearing and toxic substances removing, promoting blood circulation to restore menstrual flow, inducing diuresis to remove edema, preventing the attack (or recurrence) of malaria.Cure mainly cold, fever, laryngopharynx swelling and pain, gingival swelling and pain, jaundice due to damp-heat, dysentery, malaria, gonorrhea, edema, dysuria, blood stasis amenorrhea, dysmenorrhea ， mass in the abdomen carbuncle skin ulcer, toxic swelling, traumatic injury.
The present invention is based on the differential diagnosis of diseases of Chinese traditional treatment hysteromyoma and the dialectical principle combined, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical tune, emergency is taken in concurrently, filter out that removing blood stasis stimulates the menstrual flow, promoting blood circulation to remove blood stasis, removing food stagnancy pain relieving, solidifying heart and tranquilizing mind natural plant, according to theory of Chinese medical science prescription, formulated according to certain weight proportion, there are significant curative effect and effect to hysteromyoma.
Clinical observation:
(1) clinical data
The present inventor in 2008 so far, carries out clinical observation treatment to 195 patients with uterin leiomyoma patients.
(2) Therapeutic Method
Oral, three times on the one, each 12g, one after each meal one month is a course for the treatment of.Calculate treatment time according to conditions of patients weight, patients with mild takes 2-3 the course for the treatment of, and severe case serve on 8-12 the course for the treatment of.
(3) curative effect determinate standard
Criterion of therapeutical effect is with reference to criterion of therapeutical effect relevant in " disease of tcm judgement criterion of therapeutical effect ".
Cure: clinical symptoms all disappears, and lab testing is normal.
Effective: clinical symptoms disappears substantially, test chamber checks that each index of correlation is close to normal level.
Effective: clinical symptom relief, test chamber checks that each index of correlation makes moderate progress, and sign is improved.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
(4) clinical effectiveness
Clinical cure 210 example (78.65%), effective 31 examples (11.61%), effective 19 examples (7.12%), invalid 7 examples (2.62%), total effective rate is 97.38%.
The present invention prepares simply, good absorbing effect, and duration of efficacy is long, evident in efficacy, has no side effect, and safety is high, and production cost is low, is conducive to sufferer and alleviates condition of illness in time.
(4) detailed description of the invention
Embodiment 1:
Get Cortex Moutan 120g, Semen Persicae 50g, Ramulus Cinnamomi 50g, Poria 180g, Radix Salviae Miltiorrhizae 180g, Radix Paeoniae Rubra 50g, Rhizoma Curcumae 20g, Radix Angelicae Sinensis 50g, Ramulus Euonymi 80g, Herba Verbenae 80g, above-mentioned raw materials is cleaned up, pulverize as after powder, sieving for standby, it is for subsequent use when the immersion deliquescing of 30g Semen setariae is not rotten, material powder adds water after humidity and is mixed into Semen setariae for subsequent use, and mixed dynamic vessel make raw material powder hold Semen setariae layer by layer to become solid pill, dries for subsequent usely namely to obtain product afterwards.
Usage and dosage: oral, three times on the one, each 12g, one after each meal.
Embodiment 2:
Get Cortex Moutan 160g, Semen Persicae 90g, Ramulus Cinnamomi 90g, Poria 240g, Radix Salviae Miltiorrhizae 240g, Radix Paeoniae Rubra 90g, Rhizoma Curcumae 60g, Radix Angelicae Sinensis 90g, Ramulus Euonymi 120g, Herba Verbenae 120g, above-mentioned raw materials is cleaned up, pulverize as after powder, sieving for standby, it is for subsequent use when the immersion deliquescing of 30g Semen setariae is not rotten, material powder adds water after humidity and is mixed into Semen setariae for subsequent use, and mixed dynamic vessel make raw material powder hold Semen setariae layer by layer to become solid pill, dries for subsequent usely namely to obtain product afterwards.
Usage and dosage: oral, three times on the one, each 12g, one after each meal.
Embodiment 3:
Get Cortex Moutan 140g, Semen Persicae 70g, Ramulus Cinnamomi 70g, Poria 210g, Radix Salviae Miltiorrhizae 210g, Radix Paeoniae Rubra 70g, Rhizoma Curcumae 42g, Radix Angelicae Sinensis 70g, Ramulus Euonymi 105g, Herba Verbenae 105g, above-mentioned raw materials is cleaned up, pulverize as after powder, sieving for standby, it is for subsequent use when the immersion deliquescing of 30g Semen setariae is not rotten, material powder adds water after humidity and is mixed into Semen setariae for subsequent use, and mixed dynamic vessel make raw material powder hold Semen setariae layer by layer to become solid pill, dries for subsequent usely namely to obtain product afterwards.
Usage and dosage: oral, three times on the one, each 12g, one after each meal.
Claims (4)
1. treat the Chinese medicine for oral administration of hysteromyoma for one kind, it is characterized by, make pill by the raw material of following parts by weight: Cortex Moutan 120-160 part, Semen Persicae 50-90 part, Ramulus Cinnamomi 50-90 part, Poria 180-240 part, Radix Salviae Miltiorrhizae 180-240 part, Radix Paeoniae Rubra 50-90 part, Rhizoma Curcumae 20-60 part, Radix Angelicae Sinensis 50-90 part, Ramulus Euonymi 80-120 part, Herba Verbenae 80-120 part.
2. the Chinese medicine for oral administration for the treatment of hysteromyoma according to claim 1, it is characterized by, make pill by the raw material of following parts by weight: Cortex Moutan 140 parts, 70 parts, Semen Persicae, Ramulus Cinnamomi 70 parts, 210 parts, Poria, Radix Salviae Miltiorrhizae 210 parts, Radix Paeoniae Rubra 70 parts, Rhizoma Curcumae 42 parts, Radix Angelicae Sinensis 70 parts, Ramulus Euonymi 105 parts, Herba Verbenae 105 parts.
3. the Chinese medicine for the treatment of hysteromyoma according to claim 1 and 2, it is characterized in that: described raw material pulverizing is after powder, sieving for standby, Semen setariae is soaked deliquescing and not rotten time for subsequent use, material powder adds water after humidity and is mixed into Semen setariae for subsequent use, mixed dynamic vessel make raw material powder hold Semen setariae layer by layer to become solid pill, dry for subsequent usely namely to obtain product afterwards.
4. the Chinese medicine for the treatment of hysteromyoma according to claim 3, is characterized in that: the weight proportion of described raw material and Semen setariae is 86-130:3.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106266986A (en) * | 2016-08-29 | 2017-01-04 | 刘艳梅 | A kind of Chinese medicine composition for treating hysteromyoma |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102114222A (en) * | 2010-05-01 | 2011-07-06 | 胡海舰 | Chinese medicinal oral decoction for treating hysteromyoma |
| CN104398972A (en) * | 2014-11-05 | 2015-03-11 | 山东瑞康生命科技有限公司 | Traditional Chinese medicine treating qi-stagnation blood-stasis type hysteromyoma and preparation method |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102114222A (en) * | 2010-05-01 | 2011-07-06 | 胡海舰 | Chinese medicinal oral decoction for treating hysteromyoma |
| CN104398972A (en) * | 2014-11-05 | 2015-03-11 | 山东瑞康生命科技有限公司 | Traditional Chinese medicine treating qi-stagnation blood-stasis type hysteromyoma and preparation method |
Non-Patent Citations (1)
| Title |
|---|
| 王东青等: "小米起模机械泛丸制备水丸法", 《基层中药杂志》 * |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106266986A (en) * | 2016-08-29 | 2017-01-04 | 刘艳梅 | A kind of Chinese medicine composition for treating hysteromyoma |
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