CN113785204B - 自动分析装置的预处理方法 - Google Patents

自动分析装置的预处理方法 Download PDF

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Publication number
CN113785204B
CN113785204B CN202080032039.5A CN202080032039A CN113785204B CN 113785204 B CN113785204 B CN 113785204B CN 202080032039 A CN202080032039 A CN 202080032039A CN 113785204 B CN113785204 B CN 113785204B
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China
Prior art keywords
magnetic beads
measured
sample
substance
antibody
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Chinese (zh)
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CN113785204A (zh
Inventor
野上真
松冈晋弥
海老原大介
桥本雄一郎
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Hitachi High Tech Corp
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Hitachi High Technologies Corp
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0446—Combinations of the above

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN202080032039.5A 2019-05-08 2020-03-09 自动分析装置的预处理方法 Active CN113785204B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019088019 2019-05-08
JP2019-088019 2019-05-08
PCT/JP2020/009996 WO2020225971A1 (ja) 2019-05-08 2020-03-09 自動分析装置の前処理方法

Publications (2)

Publication Number Publication Date
CN113785204A CN113785204A (zh) 2021-12-10
CN113785204B true CN113785204B (zh) 2024-10-15

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CN202080032039.5A Active CN113785204B (zh) 2019-05-08 2020-03-09 自动分析装置的预处理方法

Country Status (5)

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US (1) US12422446B2 (https=)
EP (1) EP3968029B1 (https=)
JP (1) JP7520824B2 (https=)
CN (1) CN113785204B (https=)
WO (1) WO2020225971A1 (https=)

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* Cited by examiner, † Cited by third party
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CN115569623B (zh) * 2022-09-29 2025-02-11 安徽松羽生物系统工程有限公司 一种高效连续性磁珠母液制备装置
CN120019285A (zh) * 2022-11-08 2025-05-16 株式会社日立高新技术 自动分析装置
CN117054574A (zh) * 2023-08-08 2023-11-14 翊新诊断技术(苏州)有限公司 一种基于微流控囊袋技术的质谱样本前处理方法和应用

Citations (3)

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WO2015025378A1 (ja) * 2013-08-21 2015-02-26 株式会社日立製作所 試料分析方法及び試料分析装置
CN106574934A (zh) * 2014-07-07 2017-04-19 株式会社日立高新技术 分析装置以及分析方法
CN107850581A (zh) * 2015-12-29 2018-03-27 株式会社爱思迪科学 含有浓度显著不同的多种成分的试样的分析预处理方法

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US6027945A (en) * 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
AU2001242928A1 (en) 2000-03-16 2001-09-24 Biacore Ab Method for capturing analytes eluted from surface-bound ligands
GB0102568D0 (en) 2001-02-01 2001-03-21 Magnetic Biosolutions Sweden A Method
US20040132044A1 (en) * 2001-05-07 2004-07-08 Menachem Ritterband Magnetic beads and uses thereof
DE60308259T2 (de) 2002-05-22 2007-04-05 Sysmex Corp. Immunologische Verfahren, Vorrichtungen und Reagenzien
JP4233382B2 (ja) 2002-05-22 2009-03-04 シスメックス株式会社 免疫測定方法、免疫測定装置、及び免疫測定用試薬
JP4804344B2 (ja) 2004-03-30 2011-11-02 ユニバーサル・バイオ・リサーチ株式会社 反応性色素結合磁性粒子及びタンパク質分離精製法
JPWO2006088192A1 (ja) 2005-02-21 2008-07-03 国立大学法人 東京大学 分析用担体及びそれを用いる測定方法
AU2006299414A1 (en) * 2005-09-30 2007-04-12 Caliper Life Sciences, Inc. Microfluidic device for purifying a biological component using magnetic beads
WO2007081385A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP2220500A4 (en) 2007-11-20 2010-12-15 3M Innovative Properties Co METHOD FOR ANALYZING A BACTERIUM SAMPLE USING A POLYMER DETECTOR CONTAINING DIACETYLENE
CN103370627B (zh) 2010-10-29 2016-05-11 恩姆菲舍尔科技公司 用于样品制备和分析的自动化系统的系统布局
JP6449017B2 (ja) 2012-11-16 2019-01-09 ユニバーサル・バイオ・リサーチ株式会社 直動型反応処理装置およびその方法
JP6773402B2 (ja) * 2014-11-04 2020-10-21 三洋化成工業株式会社 磁性シリカ粒子を用いた対象物質の分離方法
CN106198963A (zh) 2016-08-31 2016-12-07 上海美吉生物医药科技有限公司 一种用于捕获白细胞的免疫磁珠及其制备方法
CN110959185B (zh) 2017-05-22 2023-06-30 拜克门寇尔特公司 具有多种检测能力的集成样品处理系统
JP2019049455A (ja) 2017-09-08 2019-03-28 東芝テック株式会社 試料調製装置及び試料調製方法
CN108333357A (zh) * 2018-02-09 2018-07-27 广州源起健康科技有限公司 一种磁珠时间分辨荧光免疫定量检测ck-mb试剂盒

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WO2015025378A1 (ja) * 2013-08-21 2015-02-26 株式会社日立製作所 試料分析方法及び試料分析装置
CN106574934A (zh) * 2014-07-07 2017-04-19 株式会社日立高新技术 分析装置以及分析方法
CN107850581A (zh) * 2015-12-29 2018-03-27 株式会社爱思迪科学 含有浓度显著不同的多种成分的试样的分析预处理方法

Also Published As

Publication number Publication date
JPWO2020225971A1 (https=) 2020-11-12
JP7520824B2 (ja) 2024-07-23
WO2020225971A1 (ja) 2020-11-12
CN113785204A (zh) 2021-12-10
EP3968029A1 (en) 2022-03-16
US20220276270A1 (en) 2022-09-01
EP3968029A4 (en) 2023-01-18
EP3968029B1 (en) 2025-05-21
US12422446B2 (en) 2025-09-23

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