CN113678979A - Solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people - Google Patents
Solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people Download PDFInfo
- Publication number
- CN113678979A CN113678979A CN202110980718.1A CN202110980718A CN113678979A CN 113678979 A CN113678979 A CN 113678979A CN 202110980718 A CN202110980718 A CN 202110980718A CN 113678979 A CN113678979 A CN 113678979A
- Authority
- CN
- China
- Prior art keywords
- insulin
- secretion
- type
- synthesis
- solid beverage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title claims abstract description 40
- 235000013361 beverage Nutrition 0.000 title claims abstract description 21
- 102000004877 Insulin Human genes 0.000 title claims abstract description 20
- 108090001061 Insulin Proteins 0.000 title claims abstract description 20
- 229940125396 insulin Drugs 0.000 title claims abstract description 20
- 230000015572 biosynthetic process Effects 0.000 title claims abstract description 19
- 230000028327 secretion Effects 0.000 title claims abstract description 19
- 238000003786 synthesis reaction Methods 0.000 title claims abstract description 19
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title claims abstract description 17
- 230000001737 promoting effect Effects 0.000 title claims abstract description 16
- 239000007787 solid Substances 0.000 title claims abstract description 16
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 16
- 239000000284 extract Substances 0.000 claims abstract description 16
- 239000011701 zinc Substances 0.000 claims abstract description 13
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 13
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims abstract description 11
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims abstract description 11
- 239000011575 calcium Substances 0.000 claims abstract description 11
- 229910052791 calcium Inorganic materials 0.000 claims abstract description 11
- 239000011591 potassium Substances 0.000 claims abstract description 11
- 229910052700 potassium Inorganic materials 0.000 claims abstract description 11
- WVXRAFOPTSTNLL-NKWVEPMBSA-N 2',3'-dideoxyadenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@H]1CC[C@@H](CO)O1 WVXRAFOPTSTNLL-NKWVEPMBSA-N 0.000 claims abstract description 8
- 241001608472 Bifidobacterium longum Species 0.000 claims abstract description 8
- 241000167854 Bourreria succulenta Species 0.000 claims abstract description 8
- 241001640002 Malpighia emarginata Species 0.000 claims abstract description 8
- 235000014837 Malpighia glabra Nutrition 0.000 claims abstract description 8
- UEDUENGHJMELGK-HYDKPPNVSA-N Stevioside Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@]12C(=C)C[C@@]3(C1)CC[C@@H]1[C@@](C)(CCC[C@]1([C@@H]3CC2)C)C(=O)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O UEDUENGHJMELGK-HYDKPPNVSA-N 0.000 claims abstract description 8
- 229940009291 bifidobacterium longum Drugs 0.000 claims abstract description 8
- 235000019693 cherries Nutrition 0.000 claims abstract description 8
- 229940013618 stevioside Drugs 0.000 claims abstract description 8
- OHHNJQXIOPOJSC-UHFFFAOYSA-N stevioside Natural products CC1(CCCC2(C)C3(C)CCC4(CC3(CCC12C)CC4=C)OC5OC(CO)C(O)C(O)C5OC6OC(CO)C(O)C(O)C6O)C(=O)OC7OC(CO)C(O)C(O)C7O OHHNJQXIOPOJSC-UHFFFAOYSA-N 0.000 claims abstract description 8
- 235000019202 steviosides Nutrition 0.000 claims abstract description 8
- 206010012601 diabetes mellitus Diseases 0.000 claims abstract description 6
- 241000193830 Bacillus <bacterium> Species 0.000 claims abstract description 4
- SHZGCJCMOBCMKK-UHFFFAOYSA-N D-mannomethylose Natural products CC1OC(O)C(O)C(O)C1O SHZGCJCMOBCMKK-UHFFFAOYSA-N 0.000 claims abstract description 4
- SHZGCJCMOBCMKK-JFNONXLTSA-N L-rhamnopyranose Chemical compound C[C@@H]1OC(O)[C@H](O)[C@H](O)[C@H]1O SHZGCJCMOBCMKK-JFNONXLTSA-N 0.000 claims abstract description 4
- PNNNRSAQSRJVSB-UHFFFAOYSA-N L-rhamnose Natural products CC(O)C(O)C(O)C(O)C=O PNNNRSAQSRJVSB-UHFFFAOYSA-N 0.000 claims abstract description 4
- 229960003975 potassium Drugs 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 5
- 238000002360 preparation method Methods 0.000 claims description 5
- HLCFGWHYROZGBI-JJKGCWMISA-M Potassium gluconate Chemical group [K+].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O HLCFGWHYROZGBI-JJKGCWMISA-M 0.000 claims description 3
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims description 3
- 229960005069 calcium Drugs 0.000 claims description 3
- 229940049920 malate Drugs 0.000 claims description 3
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 3
- 229960003189 potassium gluconate Drugs 0.000 claims description 3
- 235000013926 potassium gluconate Nutrition 0.000 claims description 3
- 239000004224 potassium gluconate Substances 0.000 claims description 3
- 235000011478 zinc gluconate Nutrition 0.000 claims description 3
- 239000011670 zinc gluconate Substances 0.000 claims description 3
- 229960000306 zinc gluconate Drugs 0.000 claims description 3
- 238000000034 method Methods 0.000 claims 1
- 238000004806 packaging method and process Methods 0.000 claims 1
- 238000005303 weighing Methods 0.000 claims 1
- 238000012986 modification Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 206010022489 Insulin Resistance Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 230000035622 drinking Effects 0.000 description 1
- 230000000667 effect on insulin Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000026683 transduction Effects 0.000 description 1
- 238000010361 transduction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/175—Rhamnosus
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/51—Bifidobacterium
- A23V2400/533—Longum
Abstract
The invention discloses a solid beverage for promoting synthesis and secretion of insulin of people with type II diabetes, belongs to the technical field of diabetes health-care beverages, and particularly relates to a formula product beverage for promoting synthesis and secretion of insulin of people with type II diabetes, which comprises the following components: apple extract APE-60, Bifidobacterium longum, rhamnosus, acerola cherry extract, calcium, potassium, zinc and stevioside T-204; the weight ratio of each component is as follows: 0.25-0.85 part of apple extract APE-60, 0.02-0.20 part of bifidobacterium longum, 0.02-0.20 part of rhamnose bacillus, 0.2-4 parts of acerola cherry extract, 0.1-0.5 part of calcium, 0.1-0.5 part of potassium, 0.01-0.05 part of zinc and 0.01-0.5 part of stevioside, wherein the weight of each part is 0.2-3 g. The formula product of the invention can promote the synthesis and secretion of insulin of type II diabetes mellitus people and help patients to recover early.
Description
Technical Field
The invention relates to the technical field of solid beverages, in particular to a solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people.
Background
The type II diabetes patients are characterized by hyperglycemia, relative lack of insulin, insulin resistance and the like, diet is an important factor influencing the onset risk of type II diabetes, the onset risk can be increased by drinking excessive sugar-containing beverage, the current health-care beverage usually has certain effects of reducing pathogenic fire, nourishing yin and beautifying, but cannot be suitable for the diabetes patients, and no beverage capable of promoting the synthesis and secretion of insulin of the diabetes patients exists.
Disclosure of Invention
In view of the technical defects, the invention aims to provide the solid beverage for promoting the synthesis and secretion of insulin of the people with type II diabetes, and the solid beverage can promote the synthesis and secretion of insulin of the people with type II diabetes.
In order to solve the technical problems, the invention adopts the following technical scheme:
the invention provides a solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people, which comprises the following components: apple extract APE-60, Bifidobacterium longum, rhamnosus, acerola cherry extract, calcium, potassium, zinc and stevioside T-204; the weight ratio of each component is as follows: 0.25-0.85 part of apple extract APE-60, 0.02-0.20 part of bifidobacterium longum, 0.02-0.20 part of rhamnose bacillus, 0.2-4 parts of acerola cherry extract, 0.1-0.5 part of calcium, 0.1-0.5 part of potassium, 0.01-0.05 part of zinc and 0.01-0.5 part of stevioside, wherein the weight of each part is 0.2-3 g. Preferably, the calcium is dicalcium malate.
Preferably, the potassium is potassium gluconate.
Preferably, the zinc is zinc gluconate.
Also relates to a preparation method of the solid beverage for promoting synthesis and secretion of insulin of people with type II diabetes, which comprises the following steps: the components are prepared into powder by adopting a conventional preparation method, the components are respectively and accurately weighed, and the powder is packaged after being fully and uniformly mixed.
The invention has the beneficial effects that: the formula product of the invention can promote the synthesis and secretion of insulin of type II diabetes mellitus people and help patients to recover early.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1 a solid beverage for promoting insulin synthesis and secretion in type II diabetics comprising the following ingredients: apple extract APE-60, Bifidobacterium longum, rhamnosus, acerola cherry extract, calcium, potassium, zinc and stevioside T-204; the weight ratio of each component is as follows: 0.25-0.85 part of apple extract APE-60, 0.02-0.20 part of bifidobacterium longum, 0.02-0.20 part of rhamnose bacillus, 0.2-4 parts of acerola cherry extract, 0.1-0.5 part of calcium, 0.1-0.5 part of potassium, 0.01-0.05 part of zinc and 0.01-0.5 part of stevioside, wherein the weight of each part is 0.2-3 g.
Further, the calcium is dicalcium malate.
Further, the potassium is potassium gluconate.
Further, the zinc is zinc gluconate.
Also relates to a preparation method of the solid beverage for promoting synthesis and secretion of insulin of people with type II diabetes, which comprises the following steps: the components are prepared into powder by adopting a conventional preparation method, the components are respectively and accurately weighed, and the powder is packaged after being fully and uniformly mixed.
Wherein zinc has transduction effect on insulin signals, and zinc metabolic disorder is very important for the development of diabetes.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (5)
1. The solid beverage for promoting synthesis and secretion of insulin of people with type II diabetes is characterized by comprising the following components: apple extract APE-60, Bifidobacterium longum, rhamnosus, acerola cherry extract, calcium, potassium, zinc and stevioside T-204; the weight ratio of each component is as follows: 0.25-0.85 part of apple extract APE-60, 0.02-0.20 part of bifidobacterium longum, 0.02-0.20 part of rhamnose bacillus, 0.2-4 parts of acerola cherry extract, 0.1-0.5 part of calcium, 0.1-0.5 part of potassium, 0.01-0.05 part of zinc and 0.01-0.5 part of stevioside, wherein the weight of each part is 0.2-3 g.
2. The solid beverage for promoting insulin synthesis and secretion in type II diabetic patients according to claim 1, wherein the calcium is dicalcium malate.
3. The solid beverage for promoting insulin synthesis and secretion in type II diabetic patients according to claim 1, wherein the potassium is potassium gluconate.
4. The solid beverage according to claim 1, wherein the zinc is zinc gluconate for promoting the synthesis and secretion of insulin in type II diabetics.
5. The method for preparing the solid beverage for promoting the synthesis and secretion of insulin of the type II diabetes mellitus people as claimed in claim 1, which comprises the following steps: preparing the components into powder by a conventional preparation method, accurately weighing the components respectively, fully mixing uniformly, and packaging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110980718.1A CN113678979A (en) | 2021-08-25 | 2021-08-25 | Solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110980718.1A CN113678979A (en) | 2021-08-25 | 2021-08-25 | Solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113678979A true CN113678979A (en) | 2021-11-23 |
Family
ID=78582384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110980718.1A Pending CN113678979A (en) | 2021-08-25 | 2021-08-25 | Solid beverage for promoting synthesis and secretion of insulin of type II diabetes mellitus people |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113678979A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102458415A (en) * | 2009-06-19 | 2012-05-16 | 丹尼斯科公司 | Bifidobacteria for treating diabetes and related conditions |
-
2021
- 2021-08-25 CN CN202110980718.1A patent/CN113678979A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102458415A (en) * | 2009-06-19 | 2012-05-16 | 丹尼斯科公司 | Bifidobacteria for treating diabetes and related conditions |
Non-Patent Citations (3)
| Title |
|---|
| JOHN STAUGHTON: "7 Best Benefits of Acerola", 《HTTPS://WWW.ORGANICFACTS.NET/HEALTH-BENEFITS/FRUIT/ACEROLA.HTML》 * |
| 苗天翼: "苹果多酚基于GLP-1受体途径降糖作用的机制研究", 《中国优秀博硕士学位论文全文数据库(硕士)医药卫生科技辑》 * |
| 魏奇等: "姬松茸提取物的降血糖作用及对糖尿病大鼠肠道菌群的影响", 《中国食品学报》 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20211123 |