CN113646334B - 癌症靶向的、病毒编码的、可调节的t细胞（catvert）或nk细胞（catvern）接头 - Google Patents

癌症靶向的、病毒编码的、可调节的t细胞（catvert）或nk细胞（catvern）接头

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CN113646334B
CN113646334B CN202080015018.2A CN202080015018A CN113646334B CN 113646334 B CN113646334 B CN 113646334B CN 202080015018 A CN202080015018 A CN 202080015018A CN 113646334 B CN113646334 B CN 113646334B
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vector
polynucleotide
cell
cells
sequence
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CN113646334A (zh
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蒂莫西·P·克里普
陈淳宇
布莱恩·胡特泽恩
马克·柯里尔
王品怡
道恩·钱德勒
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Nationwide Children's Hospital
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CN202080015018.2A 2019-02-20 2020-02-19 癌症靶向的、病毒编码的、可调节的t细胞（catvert）或nk细胞（catvern）接头 Active CN113646334B (zh)

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Application Number Priority Date Filing Date Title
US201962808264P 2019-02-20 2019-02-20
US62/808,264 2019-02-20
PCT/US2020/018806 WO2020172259A1 (en) 2019-02-20 2020-02-19 Cancer-targeted, virus-encoded, regulatable t (catvert) or nk cell (catvern) linkers

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CN113646334A CN113646334A (zh) 2021-11-12
CN113646334B true CN113646334B (zh) 2025-09-16

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US (2) US20220257760A1 (enExample)
EP (2) EP3927750A4 (enExample)
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JP7137696B2 (ja) 2019-05-14 2022-09-14 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を予防するための方法および組成物
KR20230092863A (ko) 2020-06-11 2023-06-26 프로벤션 바이오, 인코포레이티드 제1형 당뇨병을 예방하기 위한 방법 및 조성물
CN115124625B (zh) * 2021-03-24 2024-11-26 圣安生医股份有限公司 免疫调节及抗肿瘤相关纳米抗体、其核酸编码序列及应用
CN112794916B (zh) * 2021-04-08 2021-08-10 正大天晴药业集团南京顺欣制药有限公司 三特异性抗原结合构建体及构建方法和应用
AU2022261124A1 (en) * 2021-04-22 2023-10-05 Dana-Farber Cancer Institute, Inc. Compositions and methods for treating cancer
MX2023013851A (es) 2021-05-24 2023-12-08 Provention Bio Inc Metodos para el tratamiento de diabetes tipo 1.
CN116024267A (zh) * 2021-10-27 2023-04-28 江苏众红生物工程创药研究院有限公司 一种靶向肿瘤含有双特异性T细胞接合器编码基因的rAAV载体及其应用
JP2023176123A (ja) * 2022-05-31 2023-12-13 株式会社 光バイオ ウイルスベクター及びそれを含むがん細胞増殖抑制剤
US20260021206A1 (en) * 2022-07-25 2026-01-22 Vironexis Biotherapeutics Inc. Adeno-associated virus vectors and methods of their use for reducing the risk of, treating, and preventing metastasis
AU2023314618A1 (en) * 2022-07-25 2025-03-13 Research Institute At Nationwide Children's Hospital Adeno-associated virus vectors and methods of their use for reducing the risk of, treating, and preventing metastasis

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