CN113632797B - Synergistic composition for preventing and treating papaya mites - Google Patents
Synergistic composition for preventing and treating papaya mites Download PDFInfo
- Publication number
- CN113632797B CN113632797B CN202111007190.6A CN202111007190A CN113632797B CN 113632797 B CN113632797 B CN 113632797B CN 202111007190 A CN202111007190 A CN 202111007190A CN 113632797 B CN113632797 B CN 113632797B
- Authority
- CN
- China
- Prior art keywords
- thymol
- mites
- mass ratio
- pesticide
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 241000238876 Acari Species 0.000 title claims abstract description 29
- 230000002195 synergetic effect Effects 0.000 title claims abstract description 25
- 241000219173 Carica Species 0.000 title claims abstract description 20
- 239000000203 mixture Substances 0.000 title claims abstract description 19
- 235000009467 Carica papaya Nutrition 0.000 title claims abstract description 18
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims abstract description 102
- 239000005844 Thymol Substances 0.000 claims abstract description 52
- 229960000790 thymol Drugs 0.000 claims abstract description 52
- QLFZZSKTJWDQOS-YDBLARSUSA-N doramectin Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C3CCCCC3)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C QLFZZSKTJWDQOS-YDBLARSUSA-N 0.000 claims abstract description 14
- 229960003997 doramectin Drugs 0.000 claims abstract description 14
- 238000013329 compounding Methods 0.000 claims description 5
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 abstract description 23
- 229960002418 ivermectin Drugs 0.000 abstract description 23
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 abstract description 22
- 239000000575 pesticide Substances 0.000 abstract description 22
- 239000005654 Clofentezine Substances 0.000 abstract description 20
- UXADOQPNKNTIHB-UHFFFAOYSA-N clofentezine Chemical compound ClC1=CC=CC=C1C1=NN=C(C=2C(=CC=CC=2)Cl)N=N1 UXADOQPNKNTIHB-UHFFFAOYSA-N 0.000 abstract description 19
- 241000607479 Yersinia pestis Species 0.000 abstract description 16
- 239000013043 chemical agent Substances 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 5
- 206010059866 Drug resistance Diseases 0.000 abstract description 3
- 230000002147 killing effect Effects 0.000 abstract description 3
- 230000003111 delayed effect Effects 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract description 2
- 239000003814 drug Substances 0.000 description 8
- 241001454293 Tetranychus urticae Species 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 241000196324 Embryophyta Species 0.000 description 5
- 230000004071 biological effect Effects 0.000 description 5
- 235000013399 edible fruits Nutrition 0.000 description 5
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 241000238631 Hexapoda Species 0.000 description 3
- 238000003556 assay Methods 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000007921 spray Substances 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 230000001018 virulence Effects 0.000 description 3
- 241001454294 Tetranychus Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 239000012452 mother liquor Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 241001124076 Aphididae Species 0.000 description 1
- 241000219172 Caricaceae Species 0.000 description 1
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 description 1
- 241001465977 Coccoidea Species 0.000 description 1
- 239000005770 Eugenol Substances 0.000 description 1
- 241000819999 Nymphes Species 0.000 description 1
- 241000233679 Peronosporaceae Species 0.000 description 1
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 description 1
- 241000985245 Spodoptera litura Species 0.000 description 1
- 241000344246 Tetranychus cinnabarinus Species 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- RECUKUPTGUEGMW-UHFFFAOYSA-N carvacrol Chemical compound CC(C)C1=CC=C(C)C(O)=C1 RECUKUPTGUEGMW-UHFFFAOYSA-N 0.000 description 1
- HHTWOMMSBMNRKP-UHFFFAOYSA-N carvacrol Natural products CC(=C)C1=CC=C(C)C(O)=C1 HHTWOMMSBMNRKP-UHFFFAOYSA-N 0.000 description 1
- 235000007746 carvacrol Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 229960002217 eugenol Drugs 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- WYXXLXHHWYNKJF-UHFFFAOYSA-N isocarvacrol Natural products CC(C)C1=CC=C(O)C(C)=C1 WYXXLXHHWYNKJF-UHFFFAOYSA-N 0.000 description 1
- 235000015094 jam Nutrition 0.000 description 1
- 230000009916 joint effect Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 239000000447 pesticide residue Substances 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 230000029553 photosynthesis Effects 0.000 description 1
- 238000010672 photosynthesis Methods 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention relates to the technical field of pesticides, and particularly relates to a synergistic composition for preventing and treating papaya mites. A synergistic composition for preventing and treating papaya mites comprises the effective components of thymol and clofentezine, ivermectin or doramectin which are compounded in a binary manner; wherein the mass ratio of the clofentezine to the thymol is 1-5: 10-1; the mass ratio of ivermectin to thymol is 1-10: 30-1; the mass ratio of the doramectin to the thymol is 1-20: 40-1. When two effective components in the synergistic composition are compounded according to a certain mass ratio, the co-toxicity coefficient is more than 120, and the synergistic effect is shown, so that the control effect on pest mites can be obviously improved, the application amount of pesticides is reduced, the control cost of the pest mites can be reduced, and the generation of drug resistance of the pest mites can be delayed; on the basis, pesticide auxiliary materials acceptable in the pesticide pharmacy are added, so that the pesticide can be prepared into chemical agents, and the pesticide has important significance for developing novel chemical agents for preventing and killing harmful mites.
Description
Technical Field
The invention relates to the technical field of pesticides, and particularly relates to a synergistic composition for preventing and treating papaya mites.
Background
Papaya is a evergreen soft woody small tree of papaya genus of family Caricaceae, native to southern Mexico and adjacent central America, and widely planted in Taiwan, Guangdong, Guangxi and Yunnan provinces of China. Ripe fruit of papaya can be used as fruit, immature fruit can be used as cooked vegetable or pickled vegetable, and can also be processed into products such as preserved fruit, fruit juice and jam, and its seed can be used for extracting oil, and its fruit and leaf can be used for medicinal purpose.
Like crops, in the planting process of papaya, the papaya is often attacked by plant diseases and insect pests, common pests include anthracnose, ringspot mosaic disease, downy mildew, pest mites, aphids, coccid, prodenia litura and the like, wherein the pest mites are one of main pest pests which harm papaya and mainly move on the back of papaya leaves to absorb juice, the damaged leaves lack green and turn yellow to form yellow spots, the yellow spots are connected into one piece or patch to influence the photosynthesis of plants, and the leaves fall off in severe cases to further influence the yield of the growth of papaya plants. Chemical agents are common means for preventing and controlling harmful mites, but a series of problems such as drug resistance, pesticide residue, environmental pollution and the like can be caused by long-term use of a single chemical agent, so that the development of novel pesticides for preventing and controlling harmful mites has important significance.
Research shows that many plant-derived phenolic substances show higher contact killing effect on pest mites, such as: eugenol, carvacrol, thymol, and the like. Application number CN200910088809.3 discloses a thymol mite-killing microemulsion and a preparation method thereof, which can effectively prevent and control multiple pesticide mites such as tetranychus cinnabarinus, tetranychus dermatioides and tetranychus bihami; meanwhile, the structural formula, the chemical name and the physical and chemical properties of thymol are also specifically disclosed in the patent.
Compounding the effective components of the pesticide with different action mechanisms is an effective and rapid way for developing new products of the pesticide and preventing and treating resistant plant diseases and insect pests at present. After different pesticide active ingredients are compounded, three action types can be shown: additive action, synergistic action and antagonistic action. Generally, the action types of different pesticide active ingredients after being compounded can be known only through a large number of tests. Screening the compound pesticide with synergistic effect can obviously improve the control effect, reduce the pesticide use amount, reduce the control cost, delay the generation of pest resistance and reduce the pollution to the environment, and is one of the important means of the current comprehensive control of plant diseases and insect pests. The inventor discovers that the synergistic effect is shown when thymol and clofentezine, ivermectin or doramectin are compounded in a certain mass ratio range through a large number of indoor biological activity tests, which has important significance for developing novel pesticides, and related compounding reports are not seen at present.
Disclosure of Invention
The invention aims to provide a synergistic composition for preventing and treating papaya mites, which solves the problem of long-term use of a single chemical agent.
In order to achieve the purpose, the invention provides the following technical scheme:
a synergistic composition for controlling papaya mites comprises the effective components of thymol and clofentezine, ivermectin or doramectin which are compounded in a binary manner; wherein the mass ratio of the clofentezine to the thymol is 1-5: 10-1; the mass ratio of the ivermectin to the thymol is 1-10: 30-1; the mass ratio of the doramectin to the thymol is 1-20: 40-1.
Preferably, the mass ratio of the clofentezine to the thymol is 1: 5.
preferably, the mass ratio of the ivermectin to the thymol is 1: 2.
preferably, the mass ratio of the doramectin to the thymol is 5: 1.
compared with the prior art, the invention has the following beneficial effects:
when two effective components in the synergistic composition are compounded according to a certain mass ratio, the co-toxicity coefficient is more than 120, and the synergistic effect is shown, so that the control effect on pest mites can be obviously improved, the application amount of pesticides is reduced, the control cost of the pest mites can be reduced, and the generation of drug resistance of the pest mites can be delayed; on the basis, pesticide auxiliary materials acceptable in the pesticide pharmacy are added, so that the pesticide can be prepared into chemical agents, and the pesticide has important significance for developing novel chemical agents for preventing and killing harmful mites.
Detailed Description
In the following, the technical solutions of the present invention will be described clearly and completely, and it is obvious that the described embodiments are some, not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Examples: indoor activity test after thymol compounding
Reagent to be tested: 99% of thymol technical, 95% of clofentezine technical, 99% of ivermectin technical and 98% of doramectin technical;
for testing harmful mites: tetranychus urticae adopted from papaya plants is bred, bred and hatched in a laboratory to obtain a first generation nymph;
test method (refer to NT/T1154.13-2008 Standard for indoor pesticide determination 13: leaf dish spraying method)
1. Preparing the original drug into single-dose mother liquor, setting a plurality of groups of mixture ratios, and preparing 5 gradient mass concentrations by using 0.1% Tween-80 solution to mix the single-dose mother liquor and each group of mixture ratios according to an equal ratio method for later use;
2. selecting papaya leaves with consistent growth, and making into a leaf disc by using a puncher; placing a wet sponge block in a culture dish, placing filter paper on the wet sponge block, placing leaf disks on the filter paper, and placing 2 leaf disks in each dish; inoculating test mites on the leaf discs, wherein each leaf disc is inoculated with 20 heads;
3. the spray pressure of the Potter spray tower was adjusted to 1.47X 10 5 Pa; placing the culture dish on a bottom plate of a Potter spray tower for spraying, wherein the spraying liquid amount is 1mL, each treatment is repeated for 4 times, and the treatment without the medicament is used as a blank control; taking out the liquid medicine after the liquid medicine is sunk for 1min, and transferring to the temperature (25 +/-1) DEG C, the light cycle L: d, feeding under the condition of (16: 8) h;
4.48h later, the death condition of the tested harmful mites is checked, the total number of the harmful mites and the number of the dead mites are respectively recorded, the corrected death rate of each treatment is calculated, and the DPS software is used for correcting the death rateProcessing and analyzing the test data, and calculating LC of each medicament 50 And calculating the co-toxicity coefficient (CTC value) of the mixture according to the Sun Yunpei method.
P ═ K/N × 100, where P is mortality (%), K is dead number of worms, and N is total number of treated worms;
P 1 ＝(P t －P 0 )/(1－P 0 ) In which P is 1 To correct for mortality (%), P t To address mortality (%), P 0 Blank control mortality (%);
measured toxicity index (ATI) ═ standard medicament LC 50 Test agent LC 50 )×100；
Theoretical virulence index (TTI) ═ a agent virulence index × percentage of a in the mixture + B agent virulence index × percentage of B in the mixture;
co-toxicity coefficient (CTC) × 100 [ measured toxicity index (ATI) of the mixture)/Theoretical Toxicity Index (TTI) of the mixture ];
criteria are divided according to joint action: the co-toxicity coefficient (CTC) is more than or equal to 120, which shows a synergistic effect; the co-toxicity coefficient (CTC) is less than or equal to 80, and the antagonism is shown; 80< co-toxicity coefficient (CTC) <120 showed additive effect, and the experimental results are shown in tables 1-3.
TABLE 1 indoor bioactivity assay of Tetranyperazine and thymol combinations on Tetranychus urticae
| Name and proportion of the medicament | LC 50 (mg/L) | ATI | TTI | CTC |
| Clofentezine | 19.32 | 100.00 | -- | -- |
| Thymol | 124.15 | 15.56 | -- | -- |
| Clofentezine 1: thymol 10 | 24.83 | 77.81 | 23.24 | 334.84 |
| Clofentezine 1: thymol 8 | 10.37 | 186.31 | 24.94 | 746.90 |
| Clofentezine 1: thymol 5 | 7.23 | 267.22 | 29.63 | 901.71 |
| Clofentezine 1: thymol 2 | 22.24 | 86.87 | 43.71 | 198.75 |
| Clofentezine 1: thymol 1 | 18.06 | 106.98 | 57.78 | 185.14 |
| Clofentezine 2: thymol 1 | 8.22 | 235.04 | 71.85 | 327.10 |
| Clofentezine 3: thymol 1 | 16.74 | 115.41 | 78.89 | 146.29 |
| Clofentezine 5: thymol 1 | 17.31 | 111.61 | 85.93 | 129.89 |
As can be seen from Table 1, the weight ratio of clofentezine to thymol is 1-5: the cotoxicity coefficients within the range of 10-1 are all larger than 120, which shows that the biological activity of the clofentezine and the thymol to the Tetranychus urticae after the compounding can show a synergistic effect, and particularly, the mass ratio of the clofentezine to the thymol is 1: and 5, the co-toxicity coefficient reaches 901.71, and the synergistic effect is particularly obvious.
TABLE 2 indoor bioactivity assay of Ivermectin and thymol combinations on Tetranychus urticae
| Name and proportion of the medicament | LC 50 (mg/L) | ATI | TTI | CTC |
| Ivermectin | 2.63 | 100.00 | -- | -- |
| Thymol | 124.15 | 2.12 | -- | -- |
| Ivermectin 1: thymol 30 | 33.37 | 7.88 | 5.28 | 149.38 |
| Ivermectin 1: thymol 20 | 15.03 | 17.50 | 6.78 | 258.11 |
| Ivermectin 1: thymol 10 | 13.35 | 19.70 | 11.02 | 178.82 |
| Ivermectin 1: thymol 8 | 6.39 | 41.16 | 12.99 | 316.74 |
| Ivermectin 1: thymol 5 | 4.26 | 61.74 | 18.43 | 334.95 |
| Ivermectin 1: thymol 2 | 1.14 | 230.70 | 34.75 | 663.97 |
| Ivermectin 1: thymol 1 | 2.46 | 106.91 | 51.06 | 209.39 |
| Ivermectin 2: thymol 1 | 2.72 | 96.69 | 67.37 | 143.52 |
| Ivermectin 5: thymol 1 | 0.86 | 305.81 | 83.69 | 365.43 |
| Ivermectin 8: thymol 1 | 1.92 | 136.98 | 89.12 | 153.69 |
| Ivermectin 10: thymol 1 | 2.31 | 113.85 | 91.10 | 124.97 |
As can be seen from table 2, ivermectin and thymol are present in a mass ratio of 1-10: the cotoxicity coefficients within the range of 30-1 are all larger than 120, which shows that the biological activity of the compounded ivermectin and thymol on the tetranychus urticae can be shown as a synergistic effect; particularly, the mass ratio of 1: 2, the co-toxicity coefficient reaches 663.97, and the synergistic effect is particularly obvious.
TABLE 3 indoor bioactivity assay of thymol and doramectin in combination with Tetranychus urticae
As can be seen from table 3, doramectin and thymol were added at a mass ratio of 1-20: the cotoxicity coefficients within the range of 40-1 are all larger than 120, which shows that the biological activity of the compounded doramectin and thymol on the tetranychus urticae can be shown as a synergistic effect; especially, the mass ratio of 5: when 1, the co-toxicity coefficient reaches 842.31, and the synergistic effect is particularly obvious.
In conclusion, when the thymol and the clofentezine, the ivermectin or the doramectin are compounded according to a certain mass ratio, the synergistic effect is shown on the biological activity of the papaya pest mites, and compared with a single component, the control effect can be effectively improved.
Claims (2)
1. The synergistic composition for preventing and treating the papaya mites is characterized in that the effective component of the synergistic composition is formed by compounding thymol and doramectin; the mass ratio of the doramectin to the thymol is 1-20: 40-1.
2. The synergistic composition for controlling papaya mites as claimed in claim 1, where in the mass ratio of doramectin to thymol is 5: 1.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210967522.3A CN116019101B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition containing thymol for preventing and treating papaya mites |
| CN202111007190.6A CN113632797B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition for preventing and treating papaya mites |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111007190.6A CN113632797B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition for preventing and treating papaya mites |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210967522.3A Division CN116019101B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition containing thymol for preventing and treating papaya mites |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113632797A CN113632797A (en) | 2021-11-12 |
| CN113632797B true CN113632797B (en) | 2022-09-30 |
Family
ID=78424525
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111007190.6A Active CN113632797B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition for preventing and treating papaya mites |
| CN202210967522.3A Active CN116019101B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition containing thymol for preventing and treating papaya mites |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210967522.3A Active CN116019101B (en) | 2021-08-30 | 2021-08-30 | Synergistic composition containing thymol for preventing and treating papaya mites |
Country Status (1)
| Country | Link |
|---|---|
| CN (2) | CN113632797B (en) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030091657A1 (en) * | 2000-03-17 | 2003-05-15 | Helene Chiasson | Plant acaricidal compositions and method using same |
| CN101601382B (en) * | 2009-07-20 | 2012-08-22 | 中国热带农业科学院环境与植物保护研究所 | Thymol mite-killing microemulsion and preparation method thereof |
| CN102327214A (en) * | 2011-08-24 | 2012-01-25 | 西北农林科技大学 | Thymol nano-medicament and preparation method thereof |
| CN105123699B (en) * | 2015-10-22 | 2017-03-29 | 海南博士威农用化学有限公司 | A kind of insecticide and acaricide containing thymol and Nylar |
| CN105123803A (en) * | 2015-10-26 | 2015-12-09 | 唐睿 | Botanical fungicide containing thymol and kasugamycin |
| CN105638648B (en) * | 2016-01-08 | 2018-05-18 | 广州市生物防治站 | A kind of Thymol-emamectin-benzoate aqueous emulsion |
| CN110037033A (en) * | 2019-05-20 | 2019-07-23 | 海南博士威农用化学有限公司 | A kind of Pesticidal combination and its preparation containing capillary |
-
2021
- 2021-08-30 CN CN202111007190.6A patent/CN113632797B/en active Active
- 2021-08-30 CN CN202210967522.3A patent/CN116019101B/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN116019101A (en) | 2023-04-28 |
| CN113632797A (en) | 2021-11-12 |
| CN116019101B (en) | 2023-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN110973166B (en) | Application of jerusalem artichoke root extract in preparation of tea caterpillar insecticide | |
| CN1826905A (en) | Compound pesticide of triperygium wilfordii alkaloid | |
| CN112314622A (en) | Application of composition containing fosthiazate and amino-oligosaccharin in prevention and treatment of root-knot nematodes | |
| CN113632797B (en) | Synergistic composition for preventing and treating papaya mites | |
| CN101642108A (en) | Pesticidal composition with synergistic effect | |
| CN114287450B (en) | Pesticide composition for preventing and treating sugarcane thrips | |
| CN115968892B (en) | Insecticidal composition for preventing and controlling taro field red spiders | |
| CN108782573B (en) | Acaricidal composition of D-limonene and rotenone and application thereof | |
| CN109329293B (en) | Insecticidal and acaricidal composition containing chlorfenapyr and matrine | |
| CN113767923A (en) | Novel chemical agent for preventing and treating tea yellow mites | |
| CN112514903A (en) | Pesticide composition containing fenpyroximate and application thereof | |
| CN111345304A (en) | Insecticidal composition for preventing and treating red spiders of macadamia ternifolia | |
| CN104488915A (en) | insecticidal composition containing IPP | |
| CN115299446B (en) | Nanometer suspending agent composition containing chlorfenapyr | |
| CN109832295B (en) | Insecticide for preventing and treating plutella xylostella and screening method thereof | |
| CN113173886B (en) | Application of 5-p-hydroxybenzyl-2, 4-imidazolidinedione and preparation thereof in pest resistance | |
| CN113455510B (en) | Biopesticide for preventing and treating pineapple root knot nematode disease | |
| CN113973826B (en) | Application of kaempferol in preparation of insect virus synergist and synergist | |
| CN113994967B (en) | Application of coumarin in preparation of insect virus synergist and synergist | |
| CN105248446A (en) | Complex synergism insecticide and application thereof | |
| CN109315404B (en) | Application of 11-dehydrokalaineanone in antifeedant activity and inhibition of growth and development of insects | |
| CN116267954A (en) | Insecticidal and acaricidal composition for preventing and controlling cassava red spiders | |
| CN115005224A (en) | Biopesticide for preventing and treating tetranychus urticae koch | |
| CN116548466A (en) | Application of pesticide composition in preventing and controlling ginger root knot nematode | |
| CN116172016A (en) | Microbial preparation for preventing and controlling crop leaf miner as well as preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20220831 Address after: No.22 Yongwu Road, Nanning City, Guangxi Zhuang Autonomous Region Applicant after: GUANGXI SUBTROPICAL CROPS Research Institute (GUANGXI SUBTROPICAL AGRICULTURAL PRODUCTS PROCESSING RESEARCH INSTITUTE) Applicant after: Guangxi Agricultural Vocational and Technical University Address before: 530001 No. 22, Yongwu Road, Xingning District, Nanning City, Guangxi Zhuang Autonomous Region Applicant before: GUANGXI SUBTROPICAL CROPS Research Institute (GUANGXI SUBTROPICAL AGRICULTURAL PRODUCTS PROCESSING RESEARCH INSTITUTE) |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Application publication date: 20211112 Assignee: Nanning Youguo Biotechnology Co.,Ltd. Assignor: GUANGXI SUBTROPICAL CROPS Research Institute (GUANGXI SUBTROPICAL AGRICULTURAL PRODUCTS PROCESSING RESEARCH INSTITUTE) Contract record no.: X2023980046016 Denomination of invention: A Synergistic Composition for the Prevention and Control of Papaya Mites Granted publication date: 20220930 License type: Common License Record date: 20231108 |