CN1826905A - Compound pesticide of triperygium wilfordii alkaloid - Google Patents

Abstract

The invention discloses a compound microemulsion pesticide using Tripterygium wilfordii alkaloid and avermectin as the active constituent, and also comprises filler, dispersing agent for solvent and emulsifying agent. The pesticide has broader insecticidal spectrum.

Description

A kind of compound pesticide of triperygium wilfordii alkaloid

Technical field

The present invention relates to the preparation field of botanical pesticide, especially relate to the insecticide that composite other botanical pesticide of thunder godvine alkaloid is prepared from.

Background technology

In recent years, long-term a large amount of the use causes environmental pollution, kill pests natural enemy to chemical pesticide in the field, problems such as target pest develops immunity to drugs have been on the rise, especially residual chemical pesticide causes the acute poisoning incident frequently to take place especially on fruit, vegetables, has produced serious social ecological problem.For agricultural exports, the remains of pesticide content overproof has become serious trade barrier one.At present, along with the raising of people's living standard, the enhancing of health perception, to the public nuisance-free agricultural chemicals promise well, the domestic and international market demand increases gradually in the world wide.China various places forbid making and using high-toxic pesticide one after another, then begin to pay attention to the development and the exploitation of harmless boilogical agricultural chemicals, advocate the application of public nuisance-free agricultural chemicals energetically, and this provides the vast market space for biopesticides such as plant resources.

Thunder godvine (Tripterygium wilfordii Hook f.) is the Celastraceae tripterygium plant, has another name called herba fibraureae recisae root, cabbageworm medicine, just is used for medical science and the various insects of control in China a long time ago, is one of famous medicinal and pesticide plant.Since the U.S. in 1936 extracts terpene pigment trypterygine (tripterine) from the thunder godvine root, so far extract more than 100 kind of composition, be mainly alkaloids, Diterpenes, triterpenes, sesquiterpenoids, dulcin, evonymine, cupreol, glucoside and sugar etc.Wherein the thunder godvine alkaloid compound has fairly obvious control efficiency to multiple lepidoptera pests such as cabbage caterpillar, diamond-back moth, striped rice borer.But, because research is started late to the thunder godvine alkaloid, and thunder godvine plant resources itself is less, therefore, with the thunder godvine alkaloid is that the independent use cost of botanical pesticide of active component is higher, be difficult to promote, Products Development also is restricted, the domestic thunder godvine botanical pesticide product that does not still have listing so far.

(nicotine is a kind of colourless extremely faint yellow transparent oily liquid Nicotine) to nicotine, is nitrogenous alkaloidal main component in the tobacco, and the content in tobacco leaf is 1～3%.Nicotine is a kind of high-efficiency low-toxicity, low-residual, do not poison contaminated land, the plant insecticide that environment, crops and people and animals are all had no adverse effects, very remarkable to the homoptera pest control efficiency, the part lepidoptera pest also there is certain insecticidal activity, simultaneously, because the tobacco plant resource is very abundant, so nicotine has become one of botanical pesticide product of domestic agricultural insecticide usage amount maximum.

Though above-mentioned two plant species source pesticides respectively have superiority, and have also had deficiency separately, though the thunder godvine alkaloid is higher to vegetables lepidoptera pest activity, raw material resources is few, and exploitation is higher with use cost, is difficult to promote; The nicotine development cost is low, to homoptera pest preventive effect height, but relatively poor to the lepidoptera pest effect, and long-term single use insect problem such as easily develop immunity to drugs.

Summary of the invention

The present invention seeks to deficiency at above-mentioned two plant species source pesticide list agent existence, utilize thunder godvine and nicotine botanical pesticide in the advantage of killing on the target pest separately, complementation, synergistic effect by scientific and reasonable compounded technology generation, produce that a kind of insecticidal spectrum is wide, synergy, Recompounded pesticide new varieties easy to use, lower-cost, to realize the Application and Development of this botanical pesticide resource of thunder godvine on producing.

The present invention is achieved by the following technical programs:

A kind of compound pesticide of triperygium wilfordii alkaloid, the component of this insecticide and the weight percent content of each component are:

Thunder godvine alkaloid 0.1-10%

Nicotine 0.1-20%

Filler or solvent 1-99%

Diffusant, emulsifier 1-20%.

The described thunder godvine alkaloid of this insecticide, with the thunder godvine plant is raw material, separates the mixture that includes wilforine (wilforine), wilfordine (wilfordine) and these three kinds of different alkaloid monomers of wilforgine (wilforgine) at least that obtains through chemical extraction.

Described filler of this insecticide or solvent are a kind of or any two kinds mixture among silicon dried soil, precipitated calcium carbonate, powdered whiting, kaolin, white carbon or dimethylbenzene, toluene, benzene, ethanol, the methyl alcohol.

The described diffusant of this insecticide, emulsifier are a kind of or any two kinds mixture among sodium lignin sulfonate, calcium lignosulfonate, farming breast 0201, farming breast 0204, farming breast 500, farming breast 0202, newborn 600 series of farming, Nongru-700 number, farming breast 0203, the farming breast 0207.

This insecticide is mainly used to prevent and treat the insect of vegetables, paddy rice and wild rice stem, comprising: diamond-back moth, cabbage caterpillar, prodenia litura, striped rice borer, pink rice borer, aphid etc.

Beneficial effect of the present invention: the one, thunder godvine alkaloid rationally composite by with nicotine, the plant resource active substance of the different desinsection targets of two kinds of tools is made up, enlarged insecticidal spectrum, control once can reach the purpose of killing lepidoptera pest and homoptera pest simultaneously; The 2nd, reach more than 150 by reasonable composite both co-toxicity coefficient, vegetable aphid and cabbage caterpillar control efficiency reach more than 98%, the diamond-back moth control efficiency reaches more than 95%, to striped rice borer, the control of pink rice borer and prodenia litura also can reach more than 90%, compare two single agent, the control efficiency of complex preparation increases nearly 20-50%, can reduce working concentration, also promptly reduced the use cost of product more than 30%, solved the working concentration of thunder godvine botanical pesticide in development process in the past higher with resource less bottleneck problem, and meet or exceed the control efficiency (seeing Table 1-3) of chemical pesticide substantially, for the Application and Development of thunder godvine alkaloid on producing provides a new technological approaches; The 3rd, this compounded pesticides is main active ingredient with the pollution-free plant source active substance, compare with existing chemical insecticide, have toxicity low, pollute light, to advantages such as environment and beneficial organism influence are little, simultaneously, the composite of two kinds of compositions can also effectively reduce the long-term risk that causes target pest to develop immunity to drugs fast of using of unitary agent, prolongs the service life of product.Therefore, product of the present invention meets the requirement of green agriculture and pollution-less agriculture production, has development prospect preferably.

Embodiment

The present invention is described in further detail below in conjunction with embodiment.

The preparation method of embodiment 1:(compound pesticide of triperygium wilfordii alkaloid)

Comprise following step:

1) thunder godvine alkaloid extraction preparation: positions such as the root of thunder godvine, stem, skin are cleaned, dry, pulverize the back and carry out the Soxhlet extraction with organic solvents such as ethanol, extract adds water after concentrating, separate out solid, filter, dry the back directly with 5% hydrochloric acid solution extraction three times, merge hydrochloric acid extraction liquid, adjust pH value to 8 with 8% sodium hydroxide again, separate out solid, be drying to obtain the thunder godvine alkaloid after the filtration;

2) nicotine: be commercially available former medicine (Weifang Group Co.,Ltd of three strongest ones, the active ingredient nicotine content is more than 95%);

3) the reasonable assembly of tripterygium total alkaloid and nicotine: by indoor determination of activity, determine the appropriate proportioning of two kinds of active ingredients, make both co-toxicity coefficients more than 150;

4) screening of filler or solvent:, screen suitable solid packing or organic solvent carry out product as filler processing according to the chemical property and the instructions for use of active ingredient;

5) diffusant, the screening of emulsifier: utilize the agriculture chemical compounding technology, screen suitable diffusant, emulsifier is to increase the dispersive property and the field control effect of product;

6) medicaments preparation: by above proportioning, two kinds of active ingredients are fully mixed with filler or solvent in container, add diffusant simultaneously, emulsifier stirs, after filtration or last handling process such as comminution by gas stream finish the production of product, carry out the detection of active ingredient, packing.

Embodiment 2:(missible oil)

Formulated by thunder godvine alkaloid 0.5%, nicotine 2.5%, solvent methanol 20% and dimethylbenzene 72%, emulsifier farming breast 02035%, concrete preparation method is with embodiment 1.

Embodiment 3:(wetting powder)

By thunder godvine alkaloid 0.4%, nicotine 3%, filler kaolin 90.6%, diffusant sodium lignin sulfonate 5% and emulsifier farming breast 02011% are formulated, and concrete preparation method is with embodiment 1.

Embodiment 4:(concentrated milk oil)

By thunder godvine alkaloid 9%, nicotine 16%, solvent methanol 40% and toluene 22.5%, emulsifier farming breast 020410% and farming breast 5002.5%, formulated, concrete preparation method is with embodiment 1.

Test routine 5:(product control of the present invention vegetable-crop pest-insect comparative trial)

Test period: in May, 2004; In August, 2005, September;

Test site: Zhejiang Jiaxing, Yuyao, Hangzhou;

Contrast agricultural chemicals: 5% Imidacloprid missible oil, 2.5% efficient chlorine cyanogen cream (Weierda Chemical Co., Ltd., Zhejiang)

Thunder godvine plant resource compounded pesticides belongs to the low toxicity product, be applicable to the requirement that pollution-less agriculture is produced, result of the test shows: vegetable aphid and cabbage caterpillar control efficiency reach more than 98%, the diamond-back moth control efficiency reaches more than 95%, also can reach more than 90% the control of striped rice borer, pink rice borer and prodenia litura (to see Table 1).

Table 1 aphid, cabbage caterpillar comparative efficacy test (spray-on process)

Product	Mu consumption (mL)	Preventive effect (%)		When and where
					Cabbage caterpillar	Aphid
		Product one missible oil	30				98.7	99.2	In May, 2004, Zhejiang Jiaxing
Product two wetting powders	30			98.9	98.2
		Product three concentrated milk oils	4			99.7	99.8
1% thunder godvine alkaloid missible oil	50			88.5	20.5
		10% nicotine cream	50			47.7	91.7
5% Imidacloprid missible oil	20			18.9	98.9
		2.5% efficient chlorine cyanogen cream	30			95.1	95.1

Table 2 diamond-back moth, prodenia litura comparative efficacy test (spray-on process)

Product	Mu consumption (mL)	Preventive effect (%)		When and where
					Diamond-back moth	Prodenia litura
		Product one missible oil	40				95.7	91.3	In September, 2005, Zhejiang Hangzhou
Product two wetting powders	40			95.1	90.4
		Product three concentrated milk oils	5			96.1	92.8
1% thunder godvine alkaloid missible oil	80			83.9	76.9
		10% nicotine cream	70			29.7	21.8
2.5% efficient chlorine cyanogen cream	60			87.8	87.7

Table 3 striped rice borer, pink rice borer comparative efficacy test (spray-on process)

Product	Mu consumption (mL)	Preventive effect (%)		When and where
					Striped rice borer	Pink rice borer
		Product one missible oil	60				91.0	90.3	In August, 2005, Yuyao, Zhejiang (wild rice stem striped rice borer, paddy rice pink rice borer)
Product two wetting powders	60			90.2	90.0
		Product three concentrated milk oils	8			94.1	93.2
1% thunder godvine alkaloid missible oil	120			70.9	71.8
		10% nicotine cream	100			30.5	24.8
2.5% efficient chlorine cyanogen cream	80			88.2	86.3

Claims (5)

1, a kind of compound pesticide of triperygium wilfordii alkaloid is characterized in that the component of this insecticide and the weight percent content of each component are:

Thunder godvine alkaloid 0.1-10%

Nicotine 0.1-20%

Filler or solvent 1-99%

Diffusant, emulsifier 1-20%.

2, insecticide according to claim 1, it is characterized in that described thunder godvine alkaloid, with the thunder godvine plant is raw material, separates the mixture that includes wilforine (wilforine), wilfordine (wilfordine) and these three kinds of different alkaloid monomers of wilforgine (wilforgine) at least that obtains through chemical extraction.

3, insecticide according to claim 1 is characterized in that described filler or solvent are a kind of or any two kinds mixture among silicon dried soil, precipitated calcium carbonate, powdered whiting, kaolin, white carbon or dimethylbenzene, toluene, benzene, ethanol, the methyl alcohol.

4, insecticide according to claim 1, it is characterized in that described diffusant, emulsifier is a kind of or any two kinds mixture among sodium lignin sulfonate, calcium lignosulfonate, farming breast 0201, farming breast 0204, farming breast 500, farming breast 0202, newborn 600 series of farming, Nongru-700 number, farming breast 0203 and the farming breast 0207.

5, the purposes of insecticide according to claim 1 is characterized in that being used for preventing and treating pest diamond-back moth, cabbage caterpillar, prodenia litura, striped rice borer, pink rice borer, the aphid of vegetables, paddy rice and wild rice stem.