CN113607945B - 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法 - Google Patents

抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法 Download PDF

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CN113607945B
CN113607945B CN202110774906.9A CN202110774906A CN113607945B CN 113607945 B CN113607945 B CN 113607945B CN 202110774906 A CN202110774906 A CN 202110774906A CN 113607945 B CN113607945 B CN 113607945B
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bcl
cancer
tumor
treatment
antibody
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CN113607945A (zh
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G·L·菲利普斯
D·桑帕思
I·沃茨
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F Hoffmann La Roche AG
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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CN202110774906.9A 2015-07-07 2016-07-06 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法 Active CN113607945B (zh)

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US201562189610P 2015-07-07 2015-07-07
US62/189,610 2015-07-07
CN201680040184.1A CN107922504B (zh) 2015-07-07 2016-07-06 抗HER2抗体-药物缀合物和Bcl-2抑制剂的组合疗法
PCT/US2016/041184 WO2017007846A1 (en) 2015-07-07 2016-07-06 Combination therapy with an anti-her2 antibody-drug conjugate and a bcl-2 inhibitor

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