JP6910339B2 - 抗ｈｅｒ２抗体−薬物複合体とｂｃｌ−２阻害剤の併用療法 - Google Patents

抗ｈｅｒ２抗体−薬物複合体とｂｃｌ−２阻害剤の併用療法 Download PDF

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JP6910339B2
JP6910339B2 JP2018500373A JP2018500373A JP6910339B2 JP 6910339 B2 JP6910339 B2 JP 6910339B2 JP 2018500373 A JP2018500373 A JP 2018500373A JP 2018500373 A JP2018500373 A JP 2018500373A JP 6910339 B2 JP6910339 B2 JP 6910339B2
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cancer
her2
bcl
trastuzumab
treatment
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JP2018521064A5 (enExample
JP2018521064A (ja
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ゲイル ルイス フィリップス，
ゲイル ルイス フィリップス，
ディーパク サンパス，
ディーパク サンパス，
イングリッド ワーツ，
イングリッド ワーツ，
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Genentech Inc
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Genentech Inc
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
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JP2018500373A 2015-07-07 2016-07-06 抗ｈｅｒ２抗体−薬物複合体とｂｃｌ−２阻害剤の併用療法 Active JP6910339B2 (ja)

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JP2021112329A JP2021178825A (ja) 2015-07-07 2021-07-06 抗ｈｅｒ２抗体−薬物複合体とｂｃｌ−２阻害剤の併用療法

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US201562189610P 2015-07-07 2015-07-07
US62/189,610 2015-07-07
PCT/US2016/041184 WO2017007846A1 (en) 2015-07-07 2016-07-06 Combination therapy with an anti-her2 antibody-drug conjugate and a bcl-2 inhibitor

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US (5) US10898570B2 (enExample)
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KR (2) KR20240129101A (enExample)
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HUE064898T2 (hu) 2017-03-02 2024-04-28 Genentech Inc HER2-pozitív emlõrák adjuváns kezelése
CN107349426B (zh) * 2017-07-12 2018-03-23 马骥 阿司匹林与曲妥珠单抗联合或协同在肿瘤治疗中的应用
EP3980080A1 (en) * 2019-06-10 2022-04-13 Sutro Biopharma, Inc. Immunomodulator antibody drug conjugates and uses thereof
EP3980423A1 (en) 2019-06-10 2022-04-13 Sutro Biopharma, Inc. 5h-pyrrolo[3,2-d]pyrimidine-2,4-diamino compounds and antibody conjugates thereof
WO2024211811A2 (en) * 2023-04-05 2024-10-10 Frezent Biological Solutions, Inc. Methods and compositions for antibody-drug conjugates
CN119454975B (zh) * 2024-12-02 2025-10-21 中国医学科学院医学实验动物研究所 一种药物组合物在治疗癌症中的应用

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