CN113597559A - 生物分子回收器件及方法、生物分子分析器件及方法 - Google Patents
生物分子回收器件及方法、生物分子分析器件及方法 Download PDFInfo
- Publication number
- CN113597559A CN113597559A CN202080011574.2A CN202080011574A CN113597559A CN 113597559 A CN113597559 A CN 113597559A CN 202080011574 A CN202080011574 A CN 202080011574A CN 113597559 A CN113597559 A CN 113597559A
- Authority
- CN
- China
- Prior art keywords
- biomolecule
- nanowires
- recovery device
- wall
- nanowire
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/405—Concentrating samples by adsorption or absorption
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads or physically stretching molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/02—Adapting objects or devices to another
- B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
- B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0668—Trapping microscopic beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0609—Holders integrated in container to position an object
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0845—Filaments, strings, fibres, i.e. not hollow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0851—Bottom walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
- B01L2300/0858—Side walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0877—Flow chambers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0896—Nanoscaled
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Biomedical Technology (AREA)
- Fluid Mechanics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019014906 | 2019-01-30 | ||
| JP2019-014906 | 2019-01-30 | ||
| PCT/JP2020/003284 WO2020158832A1 (ja) | 2019-01-30 | 2020-01-29 | 生体分子回収デバイス並びに方法、生体分子分析デバイス並びに方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113597559A true CN113597559A (zh) | 2021-11-02 |
Family
ID=71841347
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202080011574.2A Pending CN113597559A (zh) | 2019-01-30 | 2020-01-29 | 生物分子回收器件及方法、生物分子分析器件及方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220143613A1 (https=) |
| EP (1) | EP3919917B1 (https=) |
| JP (2) | JPWO2020158832A1 (https=) |
| CN (1) | CN113597559A (https=) |
| WO (1) | WO2020158832A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115318349A (zh) * | 2022-08-11 | 2022-11-11 | 华中科技大学 | 集成二氧化钛纳米材料微流控芯片及制备与应用 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2020092688A (ja) | 2018-12-12 | 2020-06-18 | 国立大学法人東海国立大学機構 | マイクロrnaを含む体液抽出物 |
| JP7195538B2 (ja) * | 2019-03-15 | 2022-12-26 | 国立大学法人東海国立大学機構 | デバイスの製造方法、および、デバイス |
| EP4029940A4 (en) * | 2019-09-09 | 2024-02-28 | Craif Inc. | Body fluid extract containing micro rna |
| WO2022059762A1 (ja) * | 2020-09-18 | 2022-03-24 | 国立大学法人東海国立大学機構 | 生体分子の抽出方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101175991A (zh) * | 2005-05-17 | 2008-05-07 | 原子能委员会 | 带有填充纳米管的通道的微流控器件及其生产方法 |
| CN101657717A (zh) * | 2007-04-17 | 2010-02-24 | Nxp股份有限公司 | 流体分离结构以及制造流体分离结构的方法 |
| CN102046274A (zh) * | 2008-05-06 | 2011-05-04 | 原子能和代替能源委员会 | 用于从流体分离生物分子的装置 |
| WO2015137427A1 (ja) * | 2014-03-12 | 2015-09-17 | 国立大学法人名古屋大学 | 生体分子抽出用チップ、及び生体分子抽出用チップの製造方法 |
| JP2017203763A (ja) * | 2016-05-09 | 2017-11-16 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7290667B1 (en) * | 2002-07-03 | 2007-11-06 | The Regents Of The University Of California | Microfluidic sieve using intertwined, free-standing carbon nanotube mesh as active medium |
| EP2233564A3 (en) * | 2002-10-30 | 2012-11-21 | Hitachi, Ltd. | Cell culture sheet comprising a functional substrate with a group of columnar micro-pillars and its manufacturing method |
| JP2007155398A (ja) * | 2005-12-01 | 2007-06-21 | Canon Inc | 濃縮素子、及び、それを用いた化学分析装置 |
| CA2650507A1 (en) * | 2006-04-27 | 2007-11-08 | Universite De Montreal | Assessment and reduction of risk of graft-versus-host disease |
| JP2008275523A (ja) * | 2007-05-01 | 2008-11-13 | Matsushita Electric Ind Co Ltd | 液体試料分析装置 |
| DE102008015333B4 (de) * | 2008-03-20 | 2021-05-12 | Gsi Helmholtzzentrum Für Schwerionenforschung Gmbh | Nanodraht-Strukturelement, Verfahren zu dessen Herstellung, Mikroreaktorsystem und Katalysatorsystem |
| WO2012129527A2 (en) * | 2011-03-24 | 2012-09-27 | Cornell University | Biofunctional nanofibers for analyte separation in microchannels |
| JP5637953B2 (ja) * | 2011-07-26 | 2014-12-10 | 株式会社日立ハイテクノロジーズ | 核酸分析用反応デバイス |
| US20130225416A1 (en) * | 2011-11-29 | 2013-08-29 | Gabriela Altmann | Electronic sequencing |
| US9139416B2 (en) * | 2012-08-01 | 2015-09-22 | University Of South Carolina | Microfluidic devices for the generation of nano-vapor bubbles and their methods of manufacture and use |
| JP6181562B2 (ja) * | 2014-01-20 | 2017-08-16 | グンゼ株式会社 | 下半身用衣類 |
| JP6758620B2 (ja) * | 2016-03-09 | 2020-09-23 | 国立大学法人東海国立大学機構 | ナノワイヤデバイス、該ナノワイヤデバイスを含む分析装置、サンプルの加熱処理方法及びサンプルの分離方法 |
| CN107085107A (zh) * | 2017-04-17 | 2017-08-22 | 无锡准因生物科技有限公司 | 一种检测食管鳞状细胞癌循环肿瘤细胞的微流体系统及其应用 |
| TWI635041B (zh) * | 2017-06-09 | 2018-09-11 | 國立臺灣師範大學 | 微流道晶片及其製作方法 |
-
2020
- 2020-01-29 EP EP20748065.8A patent/EP3919917B1/en active Active
- 2020-01-29 JP JP2020569703A patent/JPWO2020158832A1/ja active Pending
- 2020-01-29 WO PCT/JP2020/003284 patent/WO2020158832A1/ja not_active Ceased
- 2020-01-29 CN CN202080011574.2A patent/CN113597559A/zh active Pending
- 2020-01-29 US US17/426,420 patent/US20220143613A1/en active Pending
-
2024
- 2024-04-09 JP JP2024062470A patent/JP7788174B2/ja active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101175991A (zh) * | 2005-05-17 | 2008-05-07 | 原子能委员会 | 带有填充纳米管的通道的微流控器件及其生产方法 |
| CN101657717A (zh) * | 2007-04-17 | 2010-02-24 | Nxp股份有限公司 | 流体分离结构以及制造流体分离结构的方法 |
| CN102046274A (zh) * | 2008-05-06 | 2011-05-04 | 原子能和代替能源委员会 | 用于从流体分离生物分子的装置 |
| WO2015137427A1 (ja) * | 2014-03-12 | 2015-09-17 | 国立大学法人名古屋大学 | 生体分子抽出用チップ、及び生体分子抽出用チップの製造方法 |
| JP2017203763A (ja) * | 2016-05-09 | 2017-11-16 | 住友ゴム工業株式会社 | 医療用検査装置及び細胞検査方法 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115318349A (zh) * | 2022-08-11 | 2022-11-11 | 华中科技大学 | 集成二氧化钛纳米材料微流控芯片及制备与应用 |
| CN115318349B (zh) * | 2022-08-11 | 2024-10-18 | 华中科技大学 | 集成二氧化钛纳米材料微流控芯片及制备与应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP7788174B2 (ja) | 2025-12-18 |
| JPWO2020158832A1 (https=) | 2020-08-06 |
| EP3919917A4 (en) | 2022-11-02 |
| EP3919917B1 (en) | 2025-09-17 |
| EP3919917C0 (en) | 2025-09-17 |
| WO2020158832A1 (ja) | 2020-08-06 |
| US20220143613A1 (en) | 2022-05-12 |
| EP3919917A1 (en) | 2021-12-08 |
| JP2024088754A (ja) | 2024-07-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7788174B2 (ja) | 生体分子回収デバイス並びに方法、生体分子分析デバイス並びに方法 | |
| Suwatthanarak et al. | Microfluidic-based capture and release of cancer-derived exosomes via peptide–nanowire hybrid interface | |
| JP7045418B2 (ja) | 腫瘍細胞を検出するための装置 | |
| JP2023123592A (ja) | マイクロrnaを含む体液抽出物 | |
| US10935550B2 (en) | Functionalized graphene oxide system for detecting rare cells | |
| US20150285808A1 (en) | System for detecting rare cells | |
| CN107338184A (zh) | 一种用于捕获细胞或溶液中生物分子的捕获筛及装置 | |
| JP2017517008A (ja) | 分光センサおよびその製造方法 | |
| JP2001258868A (ja) | 血液分析方法ならびに装置 | |
| CN107338185A (zh) | 一种细胞或溶液中生物分子的捕获方法 | |
| CN207276609U (zh) | 一种用于捕获细胞或溶液中生物分子的装置 | |
| US20200164375A1 (en) | Fluidic device and method for separating biomolcules | |
| CN107850540B (zh) | 制备流体样品进行激光诱导击穿光谱和成像分析的方法 | |
| WO2023023678A2 (en) | Diagnostic platform for testing exhaled breath condensate and universal biosensor | |
| CN106513066A (zh) | 一种三维多孔石墨烯微流控芯片及其石墨烯附着方法 | |
| CN207276608U (zh) | 一种用于捕获细胞或溶液中生物分子的捕获筛 | |
| CN103105423A (zh) | 带有纳米点阵列的叉指电极及其制备方法和应用 | |
| Qiu et al. | Efficient EVs separation and detection by an alumina-nanochannel-array-membrane integrated microfluidic chip and an antibody barcode biochip | |
| EP2672252A1 (en) | Sensor for detection of a target of interest | |
| US20200156073A1 (en) | Functionalized mesh and fluidic apparatus for capturing cells or molecules in solution | |
| US9322047B2 (en) | Methods of and devices for capturing circulating tumor cells | |
| Su et al. | The effect of magnetic bead size on the isolation efficiency of lung cancer cells in a serpentine microchannel with added cavities | |
| CN116124544B (zh) | 一种应用于液体活检样品的光电富集系统 | |
| Lee et al. | Hemolysis-inspired, highly sensitive, label-free IgM detection using erythrocyte membrane-functionalized nanomechanical resonators | |
| US20200150114A1 (en) | Method for capturing target cells or molecules in solution |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20211102 |