CN113546113A - Traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry and preparation method thereof Download PDF

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CN113546113A
CN113546113A CN202011523631.3A CN202011523631A CN113546113A CN 113546113 A CN113546113 A CN 113546113A CN 202011523631 A CN202011523631 A CN 202011523631A CN 113546113 A CN113546113 A CN 113546113A
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livestock
chinese medicine
traditional chinese
medicine preparation
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陈松华
陈凌云
杨勤
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Fujian Hope Biotechnology Co ltd
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Fujian Hope Biotechnology Co ltd
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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Abstract

The invention relates to the technical field of veterinary drug preparation, in particular to a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry and a preparation method thereof; the feed is prepared from the following raw materials in parts by weight: 45-60 parts of longhairy antenoron herb, 20-35 parts of sowthistle tasselflower herb, 6-12 parts of hawthorn, 3-6 parts of ginkgo leaf, 5-8 parts of fermented soybean, 6-10 parts of perilla leaf, 10-15 parts of lizhuaxiao extract, 2-5 parts of fineleaf schizonepeta herb, 7-9 parts of tidal blumea herb, 4-8 parts of cynanchum glaucescens, 5-8 parts of loquat leaf, 9-12 parts of liquorice, sucrose and a proper amount of dextrin; the traditional Chinese medicine preparation prepared by the invention has good treatment effect on respiratory diseases of livestock and poultry; moreover, the use of the sucrose and the dextrin can mask special smells given by various medicines to a certain extent, and the sucrose and the dextrin are compatible with the hawthorn, so that the feed intake of the traditional Chinese medicine preparation prepared by the invention for livestock and poultry can be effectively improved, the feed intake of the traditional Chinese medicine preparation is increased, and the active treatment effect on treating the respiratory diseases of the livestock and poultry is achieved.

Description

Traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry and preparation method thereof
Technical Field
The invention relates to the technical field of veterinary drug preparation, in particular to a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry and a preparation method thereof.
Background
The livestock and poultry mainly refer to various animals domesticated by human beings through long-term labor in order to meet the requirements of meat, eggs, milk, fur and the like, and the livestock and poultry are greatly different from wild animals and mainly have the following four points: after long-term artificial feeding, the feed is widely applied to production; the phenotype and wild animals of the transgenic plant are essentially changed, and the transgenic plant has stable artificial selection economic characters; a stable epidemic prevention and control system is formed; according to international convention.
The livestock and poultry comprise traditional livestock and poultry, mainly refer to wild animals which can normally breed offspring and have certain economic value for human beings through artificial domestication and breeding. In the process of livestock and poultry breeding, respiratory diseases almost all occur in large-scale farms, the morbidity is 30-60%, the mortality is 5-30%, and the respiratory diseases are difficult to prevent and control. Respiratory diseases include acute pneumonia and chronic mild pneumonia, and death can be caused when acute pneumonia is severe; the chronic mild pneumonia causes slow growth rate of livestock and poultry and reduction of feed conversion rate, and causes different fattening rates of livestock and poultry groups, thereby causing more serious problems. Therefore, respiratory diseases are still the main diseases affecting livestock and poultry production, and are the diseases causing the largest economic loss for livestock and poultry industry.
Although the western medicine has the advantages of high purity, quick response and the like, the western medicine also has certain side effects. Therefore, farmers mostly adopt the Chinese medicinal preparation to treat respiratory diseases of livestock and poultry in recent years. However, the traditional Chinese medicine preparation sold in the market at present has relatively poor treatment effect on livestock, which not only affects the growth of livestock, but also causes economic loss to a certain extent for farmers.
Disclosure of Invention
The invention aims to provide the traditional Chinese medicine preparation for treating the respiratory diseases of the livestock and the poultry and the preparation method thereof, and the traditional Chinese medicine preparation prepared by the invention has good treatment effect on the respiratory diseases of the livestock and the poultry; moreover, the use of the sucrose and the dextrin can mask special smells given by various medicines to a certain extent, and the sucrose and the dextrin are compatible with the hawthorn, so that the feed intake of the traditional Chinese medicine preparation prepared by the invention for livestock and poultry can be effectively improved, the feed intake of the traditional Chinese medicine preparation is increased, and the active treatment effect on treating the respiratory diseases of the livestock and poultry is achieved.
In order to achieve the purpose, the invention provides the following technical scheme:
a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry is prepared from the following raw materials in parts by weight: 45-60 parts of longhairy antenoron herb, 20-35 parts of sowthistle tasselflower herb, 6-12 parts of hawthorn, 3-6 parts of ginkgo leaf, 5-8 parts of fermented soybean, 6-10 parts of perilla leaf, 10-15 parts of lizhuaxiao extract, 2-5 parts of fineleaf schizonepeta herb, 7-9 parts of tidal blumea herb, 4-8 parts of cynanchum glaucescens, 5-8 parts of loquat leaf, 9-12 parts of liquorice, sucrose and a proper amount of dextrin.
Furthermore, the preparation method of the Hezhanxiao extract comprises the following steps:
weighing a proper amount of hydrangea macrophylla, washing, drying, crushing, grinding to 100-200 meshes, placing the hydrangea macrophylla in an extractor, adding a proper amount of ethanol solution into the extractor, carrying out reflux extraction for 2-4 hours at the temperature of 50-60 ℃, filtering after extraction is finished, and standing the obtained first filtrate to room temperature; storing and standby;
II, adding 6-12% by mass of diatomite into the first filtrate obtained in the step I, mixing and stirring uniformly, then filtering, and then sequentially passing the obtained second filtrate through a polypropylene filter element and a polyether sulfone filter element; concentrating the obtained clear liquid by sequentially passing through an ultrafiltration membrane and a nanofiltration membrane to obtain a Hezhanxiao concentrated solution;
and III, spray drying the concentrated solution of the Hezhanxiao obtained in the step II to finally obtain solid powder, namely the finished product of the Hezhanxiao extract.
Furthermore, the concentration of the ethanol solution used in the step I is 60-75%.
Furthermore, the material-liquid ratio in the reflux extraction process in the step I is 1: 7-10.
Furthermore, the solid content of the clear liquid after concentration in the step II is 8-15%.
Furthermore, the molecular weight of the ultrafiltration membrane in the step II is 8000-15000 Dal, and the molecular weight of the nanofiltration membrane is 100-200 Dal.
A preparation method of a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry comprises the following steps:
s1, accurately weighing the raw materials in sequence according to the formula amount, cleaning the raw materials except the Hezhanxiao extract, the sucrose and the dextrin, placing the cleaned raw materials in a constant-temperature drying box, and drying the raw materials at a constant temperature of 60-75 ℃; after drying, respectively crushing and grinding the raw materials; respectively storing the obtained raw material powder for later use;
s2, placing the obtained raw material powder into a frying pan, adding clear water with the mass 8-10 times of the total mass of the raw material powder into the frying pan, decocting the raw material powder with water for 2-3 times, wherein the decocting time is 40-50 min each time, after the decoction is finished, carrying out vacuum reduced pressure concentration on the obtained liquid medicine, and storing the obtained thick paste for later use;
s3, adding a proper amount of sucrose and dextrin into the thick paste obtained in the step S2, mixing and stirring uniformly, then granulating and drying to finally obtain the finished product of the traditional Chinese medicine preparation.
Further, in the step S1, the raw materials are ground to have a particle size of 100 to 200 mesh.
Further, the density of the thick paste obtained in the step S2 is 1.1-1.2 g/cm3。
Furthermore, in the step S3, the mass ratio of the sucrose to the dextrin is 3:1, and the total dosage of the sucrose and the dextrin is 18-23% of the thick paste.
Compared with the prior art, the invention has the beneficial effects that:
the invention takes Chinese medicinal herbs such as longhairy antenoron herb, flower-leaf sowthistle herb, hawthorn, ginkgo leaf, fermented soybean, perilla leaf, lizhuoxiao extract, fineleaf schizonepeta herb, tidal blumea herb, cynanchum glaucescens, loquat leaf, liquorice and the like as raw materials for preparing a Chinese medicinal preparation; the effective components of the cynanchum glaucescens extract, namely the cynanchum glaucescens B and the cynanchum glaucescens-C-mono-D-oleandrin, have good treatment effects on common respiratory diseases, and the cynanchum glaucescens extract, the tidal blumea, the fermented soybean, the schizonepeta and the cynanchum glaucescens are mutually cooperated and compatible, so that the traditional Chinese medicine preparation prepared by the invention has good treatment effects on the respiratory diseases of livestock and poultry. In addition, the hawthorn is added as an auxiliary material, so that the functions of invigorating stomach and helping digestion can be achieved, and the appetite of the livestock and poultry can be improved. The use of the sucrose and the dextrin can mask special smells emitted by various medicines to a certain extent, and the sucrose and the dextrin are compatible with the hawthorn, so that the feed intake of the traditional Chinese medicine preparation prepared by the invention for livestock and poultry can be effectively improved, the feed intake of the traditional Chinese medicine preparation is increased, and the active treatment effect on treating the respiratory diseases of the livestock and poultry is achieved.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
A traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry is prepared from the following raw materials in parts by weight: 45 parts of longhairy antenoron herb, 20 parts of sowthistle tasselflower herb, 6 parts of hawthorn, 3 parts of ginkgo leaf, 5 parts of fermented soybean, 6 parts of perilla leaf, 10 parts of henbane extract, 2 parts of fineleaf schizonepeta herb, 7 parts of tidal flush, 4 parts of cynanchum glaucescens, 5 parts of loquat leaf, 9 parts of liquorice, and proper amount of sucrose and dextrin.
The preparation method of the Hezhanxiao extract comprises the following steps:
weighing a proper amount of hydrangea macrophylla, washing, drying, crushing and grinding to 100 meshes, placing the hydrangea macrophylla in an extractor, adding a proper amount of ethanol solution into the extractor, carrying out reflux extraction on the hydrangea macrophylla for 2 hours at the temperature of 50 ℃, filtering after the extraction is finished, and standing the obtained first filtrate to room temperature; storing and standby;
II, adding 6% by mass of diatomite into the first filtrate obtained in the step I, mixing and stirring uniformly, then filtering, and then sequentially passing the obtained second filtrate through a polypropylene filter element and a polyether sulfone filter element; concentrating the obtained clear liquid by sequentially passing through an ultrafiltration membrane and a nanofiltration membrane to obtain a Hezhanxiao concentrated solution;
and III, spray drying the concentrated solution of the Hezhanxiao obtained in the step II to finally obtain solid powder, namely the finished product of the Hezhanxiao extract.
The concentration of the ethanol solution used in step I was 60%.
And (3) in the reflux extraction process in the step I, the material-liquid ratio is 1: 7.
And (5) concentrating the clear liquid in the step II to obtain 8% of solid.
In the step II, the molecular weight of the ultrafiltration membrane is 8000Dal, and the molecular weight of the nanofiltration membrane is 100 Dal.
A preparation method of a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry comprises the following steps:
s1, accurately weighing the raw materials in sequence according to the formula amount, cleaning the raw materials except the Hezhanxiao extract, the sucrose and the dextrin, placing the cleaned raw materials in a constant-temperature drying box, and drying the raw materials at a constant temperature of 60 ℃; after drying, respectively crushing and grinding the raw materials; respectively storing the obtained raw material powder for later use;
s2, placing the obtained raw material powder into a frying pan, adding clear water with the mass 8 times of the total mass of the raw material powder into the frying pan, decocting the raw material powder with water for 2 times, wherein the decocting time is 40min each time, after the decoction is finished, carrying out vacuum reduced pressure concentration on the obtained liquid medicine, and storing the obtained thick paste for later use;
s3, adding a proper amount of sucrose and dextrin into the thick paste obtained in the step S2, mixing and stirring uniformly, then granulating and drying to finally obtain the finished product of the traditional Chinese medicine preparation.
In step S1, the raw materials are ground to have a particle size of 100 mesh.
The density of the thick paste obtained in step S2 was 1.1g/cm3。
In the step S3, the mass ratio of the sucrose to the dextrin is 3:1, and the total dosage of the sucrose and the dextrin is 18% of the thick paste.
Example 2
A traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry is prepared from the following raw materials in parts by weight: 55 parts of longhairy antenoron herb, 30 parts of sowthistle tasselflower herb, 8 parts of hawthorn, 5 parts of ginkgo leaf, 6 parts of fermented soybean, 8 parts of perilla leaf, 12 parts of henbane extract, 3 parts of fineleaf schizonepeta herb, 8 parts of tidal flush, 5 parts of cynanchum glaucescens, 7 parts of loquat leaf, 10 parts of liquorice, and proper amount of sucrose and dextrin.
The preparation method of the Hezhanxiao extract comprises the following steps:
weighing a proper amount of hydrangea macrophylla, washing, drying, crushing and grinding to 150 meshes, placing the hydrangea macrophylla in an extractor, adding a proper amount of ethanol solution into the extractor, carrying out reflux extraction on the hydrangea macrophylla for 3 hours at the temperature of 55 ℃, filtering after the extraction is finished, and standing the obtained first filtrate to room temperature; storing and standby;
II, adding 10% of diatomite by mass into the first filtrate obtained in the step I, mixing and stirring uniformly, then filtering, and then sequentially passing the obtained second filtrate through a polypropylene filter element and a polyether sulfone filter element; concentrating the obtained clear liquid by sequentially passing through an ultrafiltration membrane and a nanofiltration membrane to obtain a Hezhanxiao concentrated solution;
and III, spray drying the concentrated solution of the Hezhanxiao obtained in the step II to finally obtain solid powder, namely the finished product of the Hezhanxiao extract.
The concentration of the ethanol solution used in step I was 70%.
And (3) in the reflux extraction process in the step I, the material-liquid ratio is 1: 8.
And (5) concentrating the clear liquid in the step II to obtain the product with the solid content of 10%.
In the step II, the molecular weight of the ultrafiltration membrane is 12000Dal, and the molecular weight of the nanofiltration membrane is 150 Dal.
A preparation method of a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry comprises the following steps:
s1, accurately weighing the raw materials in sequence according to the formula amount, cleaning the raw materials except the Hezhanxiao extract, the sucrose and the dextrin, placing the cleaned raw materials in a constant-temperature drying box, and drying the raw materials at a constant temperature of 65 ℃; after drying, respectively crushing and grinding the raw materials; respectively storing the obtained raw material powder for later use;
s2, placing the obtained raw material powder into a frying pan, adding clear water with the mass 9 times of the total mass of the raw material powder into the frying pan, decocting the raw material powder with water for 2 times, wherein the decocting time is 45min each time, after the decoction is finished, carrying out vacuum reduced pressure concentration on the obtained liquid medicine, and storing the obtained thick paste for later use;
s3, adding a proper amount of sucrose and dextrin into the thick paste obtained in the step S2, mixing and stirring uniformly, then granulating and drying to finally obtain the finished product of the traditional Chinese medicine preparation.
In step S1, the raw materials are ground to have a particle size of 150 mesh.
The density of the thick paste obtained in step S2 was 1.15g/cm3。
In the step S3, the mass ratio of the sucrose to the dextrin is 3:1, and the total dosage of the sucrose and the dextrin is 20% of the thick paste.
Example 3
A traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry is prepared from the following raw materials in parts by weight: 60 parts of longhairy antenoron herb, 35 parts of sowthistle tasselflower herb, 12 parts of hawthorn, 6 parts of ginkgo leaf, 8 parts of fermented soybean, 10 parts of perilla leaf, 15 parts of henbane extract, 5 parts of fineleaf schizonepeta herb, 9 parts of tidal flush, 8 parts of cynanchum glaucescens, 8 parts of loquat leaf, 12 parts of liquorice, and proper amount of sucrose and dextrin.
The preparation method of the Hezhanxiao extract comprises the following steps:
weighing a proper amount of hydrangea macrophylla, washing, drying, crushing and grinding to 200 meshes, placing the hydrangea macrophylla in an extractor, adding a proper amount of ethanol solution into the extractor, carrying out reflux extraction on the hydrangea macrophylla for 4 hours at the temperature of 60 ℃, filtering after the extraction is finished, and standing the obtained first filtrate to room temperature; storing and standby;
II, adding 12% of diatomite by mass into the first filtrate obtained in the step I, mixing and stirring uniformly, then filtering, and then sequentially passing the obtained second filtrate through a polypropylene filter element and a polyether sulfone filter element; concentrating the obtained clear liquid by sequentially passing through an ultrafiltration membrane and a nanofiltration membrane to obtain a Hezhanxiao concentrated solution;
and III, spray drying the concentrated solution of the Hezhanxiao obtained in the step II to finally obtain solid powder, namely the finished product of the Hezhanxiao extract.
The concentration of the ethanol solution used in step I was 75%.
And the material-liquid ratio in the reflux extraction process in the step I is 1: 10.
And (5) concentrating the clear liquid in the step II to obtain the product with the solid content of 15%.
In the step II, the molecular weight of the ultrafiltration membrane is 15000Dal, and the molecular weight of the nanofiltration membrane is 200 Dal.
A preparation method of a traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry comprises the following steps:
s1, accurately weighing the raw materials in sequence according to the formula amount, cleaning the raw materials except the Hezhanxiao extract, the sucrose and the dextrin, placing the cleaned raw materials in a constant-temperature drying box, and drying the raw materials at a constant temperature of 75 ℃; after drying, respectively crushing and grinding the raw materials; respectively storing the obtained raw material powder for later use;
s2, placing the obtained raw material powder into a frying pan, adding clear water with the mass 8-10 times of the total mass of the raw material powder into the frying pan, decocting the raw material powder with water for 3 times, wherein the decocting time is 50min each time, after the decoction is finished, carrying out vacuum reduced pressure concentration on the obtained liquid medicine, and storing the obtained thick paste for later use;
s3, adding a proper amount of sucrose and dextrin into the thick paste obtained in the step S2, mixing and stirring uniformly, then granulating and drying to finally obtain the finished product of the traditional Chinese medicine preparation.
In step S1, the raw materials are ground to have a particle size of 200 mesh.
The density of the thick paste obtained in step S2 was 1.2g/cm3。
In the step S3, the mass ratio of the sucrose to the dextrin is 3:1, and the total dosage of the sucrose and the dextrin is 23% of the thick paste.
Clinical treatment effect test:
test one: the number of diseased cows was about 132 cows selected from a cattle farm in Weifang City in Shandong province, wherein 96 adult cows were bred, 15 adult cows were bred, and 21 young cows were bred. The patients with short course of disease will be treated in 1-2 days, while the patients with long course of disease will be treated in about 4 days. The clinical symptoms are cyanosis of the limb periphery and visible mucous membrane of the sick cattle, emaciation, cough, asthma, dyspnea of different degrees, viscous exudates in nostrils, and reduced or abolished appetite. Among 132 sick cattle, 75 cases were diagnosed with bovine lung plague, 33 cases were diagnosed with bovine asthma, and 24 cases were diagnosed with bovine influenza, and the various diseased cattle were divided into four groups and treated with the Chinese medicinal preparations prepared in examples 1 to 3 (test examples 1 to 3) and the commercially available Chinese medicinal preparation (comparative example), respectively, and the obtained data are recorded in table 1:
TABLE 1
Figure RE-GDA0003271541700000101
And (2) test II: 80 sick chickens with infectious bronchitis in a certain chicken farm in the Weifang city of Shandong province were selected, and divided into four groups, and were treated with the Chinese medicinal preparations prepared in examples 1 to 3 (test examples 1 to 3) and the commercially available Chinese medicinal preparation (comparative example), respectively, and the obtained data are recorded in Table 2:
TABLE 2
Figure RE-GDA0003271541700000111
As can be seen from the relevant data in tables 1 and 2, compared with the comparative example, the traditional Chinese medicine preparation prepared by the invention has good treatment effect on respiratory diseases of livestock and poultry; moreover, the sucrose, the dextrin and the hawthorn are compatible with each other, so that the food intake of the traditional Chinese medicine preparation prepared by the invention by livestock and poultry can be effectively improved, the intake of the traditional Chinese medicine preparation is increased, and the active treatment effect on the respiratory diseases of the livestock and poultry is achieved. Therefore, the expanding agent prepared by the invention has wider market prospect and is more suitable for popularization.
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims (10)

1. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry is characterized by being prepared from the following raw materials in parts by weight: 45-60 parts of longhairy antenoron herb, 20-35 parts of sowthistle tasselflower herb, 6-12 parts of hawthorn, 3-6 parts of ginkgo leaf, 5-8 parts of fermented soybean, 6-10 parts of perilla leaf, 10-15 parts of lizhuaxiao extract, 2-5 parts of fineleaf schizonepeta herb, 7-9 parts of tidal blumea herb, 4-8 parts of cynanchum glaucescens, 5-8 parts of loquat leaf, 9-12 parts of liquorice, sucrose and a proper amount of dextrin.
2. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 1, wherein the preparation method of the Hezhangxiao extract comprises the following steps:
weighing a proper amount of hydrangea macrophylla, cleaning, drying, crushing, grinding to 100-200 meshes, placing the hydrangea macrophylla in an extractor, adding a proper amount of ethanol solution into the extractor, carrying out reflux extraction for 2-4 hours at the temperature of 50-60 ℃, filtering after extraction is finished, and standing the obtained first filtrate to room temperature; storing and standby;
II, adding 6-12% by mass of diatomite into the first filtrate obtained in the step I, mixing and stirring uniformly, then filtering, and then sequentially passing the obtained second filtrate through a polypropylene filter element and a polyether sulfone filter element; concentrating the obtained clear liquid by sequentially passing through an ultrafiltration membrane and a nanofiltration membrane to obtain a Hezhanxiao concentrated solution;
and III, spray drying the concentrated solution of the Hezhanxiao obtained in the step II to finally obtain solid powder, namely the finished product of the Hezhanxiao extract.
3. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 2, which is characterized in that: the concentration of the ethanol solution used in the step I is 60-75%.
4. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 2, which is characterized in that: and the material-liquid ratio in the reflux extraction process in the step I is 1: 7-10.
5. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 1, which is characterized in that: and in the step II, the solid content of the clear liquid after concentration is 8-15%.
6. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 1, which is characterized in that: in the step II, the molecular weight of the ultrafiltration membrane is 8000-15000 Dal, and the molecular weight of the nanofiltration membrane is 100-200 Dal.
7. The preparation method of the traditional Chinese medicine preparation for treating the respiratory diseases of the livestock and the poultry according to any one of claims 1 to 6, which is characterized by comprising the following steps:
s1, accurately weighing the raw materials in sequence according to the formula amount, cleaning the raw materials except the Hezhanxiao extract, the sucrose and the dextrin, placing the cleaned raw materials in a constant-temperature drying box, and drying the raw materials at a constant temperature of 60-75 ℃; after drying, respectively crushing and grinding the raw materials; respectively storing the obtained raw material powder for later use;
s2, placing the obtained raw material powder into a frying pan, adding clear water with the mass 8-10 times of the total mass of the raw material powder into the frying pan, decocting the raw material powder with water for 2-3 times, wherein the decocting time is 40-50 min each time, after the decoction is finished, carrying out vacuum reduced pressure concentration on the obtained liquid medicine, and storing the obtained thick paste for later use;
s3, adding a proper amount of sucrose and dextrin into the thick paste obtained in the step S2, mixing and stirring uniformly, then granulating and drying to finally obtain the finished product of the traditional Chinese medicine preparation.
8. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 7, which is characterized in that: in the step S1, the particle size of each raw material is 100-200 meshes after grinding treatment.
9. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 7, which is characterized in that: the density of the thick paste obtained in the step S2 is 1.1-1.2 g/cm 3.
10. The traditional Chinese medicine preparation for treating respiratory diseases of livestock and poultry according to claim 7, which is characterized in that: in the step S3, the mass ratio of the sucrose to the dextrin is 3:1, and the total dosage of the sucrose and the dextrin is 18-23% of the thick paste.
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101006825A (en) * 2007-01-29 2007-08-01 蔡向源 A fowls and livestock feed capable of preventing bird flu effectively and its preparation
CN104288265A (en) * 2014-11-04 2015-01-21 禤燕华 Traditional Chinese medicinal composition for treating acute laryngitis
CN110526947A (en) * 2019-08-17 2019-12-03 赣州禾绿康健生物技术有限公司 A kind of preparation method of the ginsenoside extract for beverage

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101006825A (en) * 2007-01-29 2007-08-01 蔡向源 A fowls and livestock feed capable of preventing bird flu effectively and its preparation
CN104288265A (en) * 2014-11-04 2015-01-21 禤燕华 Traditional Chinese medicinal composition for treating acute laryngitis
CN110526947A (en) * 2019-08-17 2019-12-03 赣州禾绿康健生物技术有限公司 A kind of preparation method of the ginsenoside extract for beverage

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