CN103623121B - A kind of for thousand order Chinese veterinary drug preparation of preventing and treating livestock and birds respiratory disease and preparation method thereof - Google Patents
A kind of for thousand order Chinese veterinary drug preparation of preventing and treating livestock and birds respiratory disease and preparation method thereof Download PDFInfo
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Abstract
The invention provides and a kind ofly prevent and treat poultry and cause thousand order Chinese veterinary drug preparation of respiratory tract disease because of antibacterial, virus, mycoplasma etc., it is characterized in that the Chinese herbal medicine mixed preparing pressing row parts by weight proportioning forms: Flos Daturae 8-15 part, Herba Ephedrae 8-15 part, Semen Armeniacae Amarum (stir-fry) 7-14 part, Semen Raphani 6-13 part, Herba Artemisiae Annuae 6-11 part, sky Radix Linderae 6-11 part, Radix Stephaniae Tetrandrae 6-9 part, Herba Taraxaci 4-5 part, Radix Et Rhizoma Rhei 3-5 part, Radix Glycyrrhizae 3-5 part.Its preparation method is as follows: above-mentioned each composition Chinese medicine is adopted gained raw material Homogeneous phase mixing in proportion after the broken and superfine comminution at low temperature of coarse powder, cold drying, low-temperature fine powder, to obtain final product.Gained herbal raw material just can be applicable to this preparation according to following quality standard, its quality standard is: whole plant particle diameter reaches 12.5um(and crosses 1000 orders), moisture content is less than 5%, and consumption is the 1/5-1/3 of identical prescription coarse powder (crossing 80 orders), and bioavailability is greater than 99%.Resources of Chinese medicinal herb of the present invention is extensive, cost is low, cure rate is high, and medicine noresidue, has no side effect.
Description
Background technology
In recent years, along with cultivation intensive degree improves, the respiratory tract disease of poultry, in the trend constantly risen, causes the cause of disease of livestock and birds respiratory disease to mainly contain antibacterial, virus, mycoplasma or its mixed infection etc.The mycoplasma pneumoniae respiratory tract disease that current domestic animal the most easily sends out, main symptom is cough for a long time, has a strong impact on the fertility performance of domestic animal; After wean, piglet falls ill then easy concurrent Other diseases for a long time, and performance respiratory complication, cardinal symptom is the symptoms such as accelerated breathing, dyspnea, heating, and mortality rate reaches 20-50%, often causes destructive strike to aquaculture.Poultry chronic respiratory tract disease is poultry frequently-occurring disease, particularly under season alternation and severe winter weather conditions, and sick fowl performance mouth breathing, cough, badly influences growth and the fertility performance (as laying eggs) of poultry; The prolonged illness more poultry then easy viral respiratory disease such as mixed infection man avian infectious laryngotracheitis and bronchitis, sick fowl larynx trachea secretes a large amount of thick sputum can not expectoration, and cause poultry to be choked to death, mortality rate is up to 10-60%.Therefore livestock and birds respiratory disease often causes huge economic loss to aquaculture, seriously governs the development of aviculture.
The measure of current control livestock and birds respiratory disease mainly contains and improves feeding and management condition, immunity inoculation and medicine prevention and control etc.Livestock and birds respiratory disease by strengthening feeding and management, good ventilation, temperature control and reduce stocking density being alleviated or preventing, often can reach good effect, but stocking density can be difficult to reach desirable degree at present.Immunity inoculation is a kind of effective way of prevention and control livestock and birds respiratory disease, but only has part or most poultry can adaptive immune protection, and particularly current livestock and poultry mycoplasma vaccine potency is not high, is difficult to play protection truly to poultry.Chemoprophylaxis and controlling as current prevention and control livestock and birds respiratory disease comparatively effective ways, but more increase the weight of along with epidemic situation, pathogen continues to increase chemical drugs drug resistance, and curative effect reduces, and consumption strengthens, and causes dieing young of environment.Herbal medicine is natural materials, and for the medical soul of China is precious, its determined curative effect, treating both the principal and secondary aspects of a disease, does not produce drug resistance, and noresidue is renewable, will become a direction of following veterinary drug development.
Herbal medicine makes various dosage form easy to use, as sheet powder, injection etc. mainly through comminuting method and extraction method at present.Chinese medicine extraction can extract active ingredient in Chinese medicine, makes various preparation impurity few, uses with strong points, but highly energy-consuming, lose simultaneously or change some composition in Chinese medicine, being generally injection and adopting.Pulverize and then rely on physics method completely, original composition of Chinese medicine can be retained completely, at utmost play the usefulness of herbal medicine." thousand order Chinese veterinary drug preparation " is crushed to thousand orders by special disintegrating process, has that consumption is few, good effect, a feature such as easy to use, and product will have wide market prospect.
Summary of the invention
The object of the invention is to overcome above-mentioned weak point, providing a kind of take natural Chinese medicines as composition, raising prevention effect, the Chinese medicine preparation reducing the control livestock and birds respiratory disease of drug cost and preparation method thereof.Implementation of the present invention is as follows for achieving the above object:
Prevent and treat a Chinese veterinary drug preparation for livestock and birds respiratory disease, it is characterized in that parts by weight proportioning is: Flos Daturae 8-15 part, Herba Ephedrae 8-15 part, Semen Armeniacae Amarum (stir-fry) 7-14 part, Semen Raphani 6-13 part, Herba Artemisiae Annuae 6-11 part, sky Radix Linderae 6-11 part, Radix Stephaniae Tetrandrae 6-9 part, Herba Taraxaci 4-5 part, Radix Et Rhizoma Rhei 3-5 part, Radix Glycyrrhizae 3-5 part.
The present invention prevents and treats the preparation method of the Chinese veterinary drug preparation of livestock and birds respiratory disease, it is characterized in that: the first coarse powder of every taste Chinese medicine is to 20-40 order, rear low temperature rapid draing, low-temperature fine powder broken (crossing 200-500 order), superfine comminution at low temperature (crossing 1000 orders), for subsequent use; Take according to each taste Chinese medicine number in prescription is enough, add in blender and stir 20-30 minute, packaging, to obtain final product.
Prescription described in Chinese herbal and crude drugs preparations of the present invention is:
1. all plant particle diameter reaches 12.5um(and crosses 1000 orders);
2. moisture content is less than 5%;
3. consumption is the 1/5-1/3 of coarse powder (80 order);
4. bioavailability is not less than 99%.
Composition principle:
Flos Daturae: nature and flavor are pungent, temperature, poisonous; Return lung, Liver Channel.Tool antiasthmatic-antitussive, the function of analgesia spasmolytic.Cure mainly cough with asthma dyspnea with rapid respiration, tripe abdomen cold type of pain, arthralgia due to cold-dampnes.
Herba Ephedrae: pungent, the micro-hardship of nature and flavor, temperature.Return lung, urinary bladder channel.Tool induces sweat cold expelling, depressed lung-energy dispersing, the function of inducing diuresis to remove edema.Cure mainly affection of exogenous wind-cold, cough, asthma, edema.
Semen Armeniacae Amarum (stir-fry): nature and flavor are bitter, tepor; Slightly poisonous.Return lung, large intestine channel.Tool relieving cough and asthma, the function of loosening bowel to relieve constipation.Cure mainly cough and asthma, dryness of the intestine constipation.
Semen Raphani: nature and flavor are pungent, sweet, flat.Return lung, spleen, stomach warp.Tool dyspepsia and intestinal stasis relieving, the function of lowering the adverse-rising QI to resolve phlegm.Cure mainly stagnation of QI food stagnation, abdominal distention, phlegm retention cough with asthma.
Herba Artemisiae Annuae: nature and flavor bitter, acrid, cold.Return liver, gallbladder meridian.Tool clearing away summer-heat, reducing the asthenic fever, the function of protozoacide.Cure mainly diseases caused by exogenous pathogenic factor summer-heat, fever due to yin deficiency, jaundice due to damp-heat, babesiasis, coccidiosis.
It Radix Linderae: nature and flavor are pungent, temperature.Enter spleen, lung, kidney, urinary bladder channel.There are promoting the circulation of QI to relieve pain, effect of warming kidney for dispelling cold.Cure mainly all pain cards of breast abdomen caused by QI stagnated by cold, frequent micturition, the enuresis.
Radix Stephaniae Tetrandrae: nature and flavor are bitter, cold.Return bladder, lung meridian.Tool inducing diuresis to remove edema, the function of wind-expelling pain-stopping.Cure mainly difficulty in urination, edema, rheumatic arthralgia, arthralgia.
Herba Taraxaci: nature and flavor are bitter, sweet, cold.Return liver, stomach warp.Tool heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, the function of inducing diuresis for treating stranguria syndrome.Cure mainly sore, acute mastitis, conjunctival congestion, pharyngalgia, jaundice due to damp-heat, pyretic stranguria.
Radix Et Rhizoma Rhei: nature and flavor are bitter, cold.Return spleen, stomach, large intestine, liver, pericardium channel.Tool purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, the function of removing mass clots absorbing.Cure mainly excess-heat constipation, combined symptoms, the yellow furunculosis of skin ulcer, conjunctival congestion and swelling pain, empyrosis, traumatic injury.
Radix Glycyrrhizae: nature and flavor are sweet, flat.GUIXIN, lung, spleen, stomach warp.Tool invigorating the spleen and replenishing QI, expelling phlegm for arresting cough, and middle emergency, removing toxic substances, coordinating the actions of various ingredients in a prescription, cushion toxicity, strong function.Cure mainly weakness of the spleen and stomach, lassitude, cough with asthma, laryngopharynx swelling and pain, poisoning, skin infection.
Wherein based on Flos Daturae, Herba Ephedrae, Semen Armeniacae Amarum (stir-fry), Semen Raphani, Herba Artemisiae Annuae, sky Radix Linderae, Radix Stephaniae Tetrandrae are auxiliary, and Herba Taraxaci, Radix Et Rhizoma Rhei are assistant, and Radix Glycyrrhizae is for making, and all medicines match, and jointly reaches that lung qi dispersing expels the heat-evil, effect of antiasthmatic-antitussive.For warm, the lung-heat asthma that heat in blood etc. cause, cough, mycoplasma etc.All diseases can be made after taking to be fully recovered.
During use, by this medicated powder in 0. 1-5% ratios or raise certain consumption by every boss and stir in feedstuff or be mixed in drinking-water, can effectively prevent and treat the livestock and birds respiratory disease caused by a variety of causes.
Feature of the present invention is: medicine of the present invention is pure Chinese medicine composition, and formula is reasonable.Its combination principle is " lung qi dispersing purges heat, antiasthmatic-antitussive ", and the pharmacological action that the different medicine of compatibility embodies also has difference.Said medicine compatibility, is comprehensively able to treating both the principal and secondary aspects of a disease, strengthening vital QI to eliminate pathogenic factors, across-the-board regulation, Yin Yang balancing.Invention formulation has significant effect to the respiratory tract disease that poultry a variety of causes causes, and curative effect is better than Chinese medicine preparation and other Western medicine preparation of folk prescription, is also better than the coarse powder Chinese veterinary drug preparation of identical compatibility simultaneously.Preparation adopts raw material Chinese medicine wide material sources, and cost is low, good effect, good palatability (without specificity bitterness), and (can mix drink) easy to use, medicine noresidue, has no side effect.
Detailed description of the invention
below in conjunction with preferred embodiments, to according to detailed description of the invention provided by the invention, details are as follows:
embodiment 1
Flos Daturae 110g, Herba Ephedrae 110g, Semen Armeniacae Amarum (stir-fry) 105g, Semen Raphani 90g, Herba Artemisiae Annuae 85g, sky Radix Linderae 85g, Radix Stephaniae Tetrandrae 75g, Herba Taraxaci 45g, Radix Et Rhizoma Rhei 40g, Radix Glycyrrhizae 40g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 2
Flos Daturae 120g, Herba Ephedrae 120g, Semen Armeniacae Amarum (stir-fry) 115g, Semen Raphani 100g, Herba Artemisiae Annuae 95g, sky Radix Linderae 95g, Radix Stephaniae Tetrandrae 85g, Herba Taraxaci 50g, Radix Et Rhizoma Rhei 40g, Radix Glycyrrhizae 40g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 3
Flos Daturae 135g, Herba Ephedrae 135g, Semen Armeniacae Amarum (stir-fry) 130g, Semen Raphani 115g, Herba Artemisiae Annuae 100g, sky Radix Linderae 100g, Radix Stephaniae Tetrandrae 85g, Herba Taraxaci 50g, Radix Et Rhizoma Rhei 45g, Radix Glycyrrhizae 45g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 4
Flos Daturae 150g, Herba Ephedrae 150g, Semen Armeniacae Amarum (stir-fry) 70g, Semen Raphani 60g, Herba Artemisiae Annuae 110g, sky Radix Linderae 110g, Radix Stephaniae Tetrandrae 60g, Herba Taraxaci 40g, Radix Et Rhizoma Rhei 50g, Radix Glycyrrhizae 50g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 5
Flos Daturae 80g, Herba Ephedrae 80g, Semen Armeniacae Amarum (stir-fry) 70g, Semen Raphani 60g, Herba Artemisiae Annuae 60g, sky Radix Linderae 60g, Radix Stephaniae Tetrandrae 60g, Herba Taraxaci 40g, Radix Et Rhizoma Rhei 30g, Radix Glycyrrhizae 30g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 6
Flos Daturae 90g, Herba Ephedrae 90g, Semen Armeniacae Amarum (stir-fry) 80g, Semen Raphani 65g, Herba Artemisiae Annuae 65g, sky Radix Linderae 65g, Radix Stephaniae Tetrandrae 65g, Herba Taraxaci 45g, Radix Et Rhizoma Rhei 30g, Radix Glycyrrhizae 30g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 7
Flos Daturae 100g, Herba Ephedrae 100g, Semen Armeniacae Amarum (stir-fry) 90g, Semen Raphani 70g, Herba Artemisiae Annuae 70g, sky Radix Linderae 70g, Radix Stephaniae Tetrandrae 70g, Herba Taraxaci 45g, Radix Et Rhizoma Rhei 35g, Radix Glycyrrhizae 35g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 8
Flos Daturae 105g, Herba Ephedrae 105g, Semen Armeniacae Amarum (stir-fry) 95g, Semen Raphani 80g, Herba Artemisiae Annuae 75g, sky Radix Linderae 75g, Radix Stephaniae Tetrandrae 70g, Herba Taraxaci 40g, Radix Et Rhizoma Rhei 35g, Radix Glycyrrhizae 35g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
embodiment 9
Flos Daturae 80g, Herba Ephedrae 80g, Semen Armeniacae Amarum (stir-fry) 140g, Semen Raphani 130g, Herba Artemisiae Annuae 60g, sky Radix Linderae 60g, Radix Stephaniae Tetrandrae 90g, Herba Taraxaci 50g, Radix Et Rhizoma Rhei 30g, Radix Glycyrrhizae 30g.
Above-mentioned each component is checked routinely, is ground into ultra-micro powder, cross 1000 orders, through laser particle analyzer or micro-mensuration, detect and qualifiedly weigh mixing in proportion again, subpackage, can obtain.
apply effect of drugs of the present invention citing:
application example 1
Test site is the Bin Yuanzhong pig farm, Pingxiang of Pingxiang Jiangxi.Pig farm has livestock on hand sow 410 remainder, wherein replacement gilt about 110, and other has preparation export trade kind piglet livestock on hand 2200 remainder.On October 12nd, 2011, have the piglet of hurdle pig about 320 remainder to fall ill, its average weight 35kg, the rear clinical treatment that is used as is tested.There is respiratory tract disease 2 days in test pig, the performance of morbidity pig is breathed urgent, the diseases such as heating, loss of appetite, does not rise sleepingly, involves rapidly full group afterwards, cuing open inspection main manifestations is that thoracic cavity cellulosic oozes out, and pericardial effusion, Binding experiment room is diagnosed as porcine contagious pleuropneumonia disease.Sequela swinery drinks water rapidly and takes invention formulation, drinking-water concentration is 2000ppm, indivedual serious symptom pig adopts the continuous symptomatic treatment 2-3 days of florfenicol injection, take invention formulation after 4 days, swinery respiratory symptom alleviates, and continues to take 3 days transference cures, and swinery searches for food recovery, after continue decrement medication a couple of days again, swinery respiratory tract disease loses recurrence.Through statistics, this preparation reaches 97% to the respiratory tract disease effective percentage that porcine contagious pleuropneumonia causes, and cure rate reaches 94%.
application example 2
Test site is the beautiful pig farm of Sun Min high on Jiangxi.In December, 2011, this has the first sequela of the growing and fattening pigs of 720 remainder different weights, and rear full group is used for Clinical Treatment Test.Morbidity is through being that column home ventilation condition is bad because weather is sombre, and swinery has the symptom pig that breathes on a small quantity to occur, involves rapidly full group afterwards, and sickness rate reaches more than 30%, is mycoplasma pneumoniae of swine by power laboratory diagnosis.Raise main priority tylosin and the treatment of florfenicol spice, after a couple of days, the state of an illness obtains certain control, but after drug withdrawal one week, palindromia, continue to use tylosin and florfenicol treatment, unsatisfactory curative effect, has a strong impact on fertility performance and the incubation rate of swinery.After change spice and take invention formulation, using dosage is 4000ppm, and simultaneously auxiliary with trophism multidimensional, after taking medicine one week, result shows, employing invention formulation has shown obvious curative effects.Swinery appetite is recovered, the ruddy light of fur, and breathe steadily, the mental status is clearly better, symptom all disappears, and effective percentage reaches 99%, and cure rate rate reaches 96%, occur without secondary disease or complication afterwards, reach the effect for the treatment of both the principal and secondary aspects of a disease, rear continuation half amount use is consolidated disease for 5 days further.
application example 3
Test site is Feng Xiang, Yichuan cultivation company limited of Jiangxi ten thousand years.There are 360 remainder sows and 1200 remainder piglet and big porkers in the hurdle that coexists, pig farm.Start at the beginning of 2011 8 months, have pig to start morbidity, sick pig performance Gao Reda 42 DEG C; Depressed, the loss of appetite of spirit, thirsty; Do not rise sleepingly, gather heap, dog sits; Skin rubefaction, ear, hypogastrium, buttocks are pale; Part pig performance dyspnea, cough, breathe, eye frame has secretions; Part pig shows as constipation, feces dry bulb shape; Typical case in deteriorated blood symptom, dermathemia and hemorrhage.Pathology: lymph nodes of body as a whole edema, serious pulmonary consolidation, interstitial lung edema, whole lung has the pathological changes of redness or purple, lobus cardiacus, obvious every leaf; There is petechia etc. on the surface of intracardiac, adventitia and kidney, is the respiratory complication caused by the concurrent contagious pleuropneumonia of reproductive and respiratory syndrome after testing, and swinery distributes certain swine fever simultaneously.Invention formulation taken by rear full group's drinking-water, and by the mixed drink of 5000ppm, full group promptly inoculates and exempts from source swine Fever Vaccine simultaneously, do not take other medicines, after taking medicine one week, except the death that disease is heavier, other equal appetite is recovered, and body temperature is normal, and the mental status is clearly better, feed intake increases, and feces is clearly better, and aubergine skin fades, breathe steadily, symptom disappears substantially, and effective percentage reaches 95%, cure rate reaches 93%, continues half amount use one week, occurs without secondary disease or complication.
application example 4
Test site is that cattle farm fattened in the newly dry English that shakes of Jiangxi Xingan.In mid-March, 2011, a collection of Nanyang Cross Beef Cattle 80 remainder is buied in this cattle farm from Henan, and its size 80 kilograms to 130 kilograms is not etc.When raising to May, there are 10 cattle phase secondary diseases, and dead 2, the high heat of sick cattle performance, more than 41.5 DEG C; Spirit is depressed, thirsty, loss of appetite, sleeping ground do not rise, cud air-blowing; Part cattle performance stream nose liquid, breathe, dyspnea, eyes have secretions; Dead cattle cuts open inspection, and pathological change is lymph nodes of body as a whole edema, serious pulmonary consolidation, and the necrosis having redness or purple, solidifying that blood appearance is serious is bad.Be cattle metachromia pleuropneumonia through Laboratory Diagnosed.Admix in concentrate with invention formulation after morbidity and take invention formulation, day dosing powder 4kg(on average every cattle 50g), loss of appetite cattle is taked to feed, injection symptomatic treatment is carried out to heating cattle analgin injection simultaneously.After taking medicine ten days, result shows, adopt invention formulation treatment to have obvious curative effects, morbidity Niu Tiwen reduces, and appetite is recovered, the mental status is clearly better, feed intake increases, and breathes steadily, transference cure, only have two routine serious symptom cattle dead after medication, effective percentage reaches 98%, and cure rate reaches 97%, and without secondary disease or complication.
application example 5
Test site is the Yang Zhong brightness family sheepwalk in the Xiajiang, Jiangxi.This buys boer goat 96 fattening from Shandong, its body weight 25-50kg is not etc.On August 18th, 2013, spirit is depressed to have bull sheep to occur after owner herded the same day, within second day, occurs the sick sheep of 10 remainders, and dead 8 very soon, the high heat of sick sheep performance high heat more than 41.5; Depressed, the loss of appetite of spirit, sleeping ground do not rise, fur slightly disorderly, sheep on one's deathbed before performance extremely dyspnea, have canthus secretions; In typical deteriorated blood symptom; Dermathemia and hemorrhage.Pathology: lymph nodes of body as a whole edema is congested, and mesentery, subcutaneous fat, liver, heart have petechia, hydroabdomen, and hydropericardium also has fiber bacterium property to ooze out.Binding experiment room is diagnosed as Pulmonis caprae seu ovis epidemic disease.Rear mixed drink-service invention formulation rapidly, day dosing powder 3kg(on average every 35g), for occurring serious symptoms sheep combination injection ceftiofur sodium injection for curing.Medication is after one week, and body temperature reduces, and appetite is recovered, and the mental status is clearly better, and feed intake increases, and breathe steadily, symptom disappears substantially.Except 2 death that symptom is heavier, do not have new cases, cure rate reaches 97%, there is no secondary disease or complication.Result shows, adopting invention formulation to prevent and treat the respiratory tract disease caused by sheep pasteurellosis bacillus has obvious curative effects.
application example 6
Test site is the Jiangxi blue or green haze kind chicken house recommended properly qualified persons for service in Jiangxi.This kind of chicken house has livestock on hand Brood Laying hens more than 20,000 plumage, after to make preparations for sowing chicken more than 10,000 plumage, the every hardware of chicken house and software facility better, management level are better, but the chronic respiratory tract disease that standby chicken group is caused by mycoplasma gallinarum happens occasionally, and often repeatedly, do not effected a radical cure, have a strong impact on chicken group fertility performance, bring very large economic loss to kind of a chicken house.In April, 2012, have a standby hen house about totally 3000 plumages more than 80 age in days standby chickens start fragmentary morbidity, carry out drinking-water treatment with tylosin tartrate soluble powder, chicken group be not effectively controlled, rear respiratory tract case is on the increase, and sickness rate reaches 20%, and occurs the death of some.Rear mixed drink-service invention formulation rapidly, the average every plumage 1g of day dosing powder 3kg(), without other medicines.Medication is after one week, and feed intake recovers normal, and the mental status is clearly better, and does not get rid of head and the generation of cough symptom.Effective percentage reaches 99%, and cure rate reaches 97%, there is no secondary disease or complication.Result shows, adopting invention formulation to prevent and treat the chronic respiratory tract disease caused by mycoplasma gallinarum has obvious curative effects.
application example 7
Test site is that the Luo Laifa of Fengcheng supports duck canopy.90 age in days standby laying ducks more than 1800 plumages are supported in this foster duck shelf rearing, due to management and environmental health condition poor, in early November, 2012 start morbidity, duck group shows respiratory tract disease, sick duck cough, necking down, is reluctant lower water, after several days every day dead more than 10 plumages, through cuing open inspection, the many mucus of larynx, liver has canescence point, small intestinal is muco-enteritis symptom, is the dfuck cholera that duck pasteurellosis bacillus causes through Laboratory Diagnosed.Rear mixed feeding rapidly takes invention formulation, average every plumage 1. 5g of day dosing powder 2. 5kg(), simultaneously with the use of trophism medicinal electrolytic multidimensional.Medication is after 3 days, and duck group death is controlled, and rear continuation medication is after 5 days, and appetite is recovered, and the mental status is good, symptom of not coughing.Invention formulation effective percentage reaches 98%, and cure rate reaches 96%, there is no secondary disease or complication.Result shows, adopting invention formulation to prevent and treat the acute respiratory disease cholera caused by duck pasteurellosis bacillus has obvious curative effects.
More than illustrate that medicine of the present invention has the high good result of cure rate, its effective percentage all reaches more than 95%, and cure rate reaches more than 93%, belongs to product safe, effective, easy to use.
The above-mentioned detailed description with reference to implementing to carry out this " a kind of for thousand order Chinese veterinary drug preparation of preventing and treating livestock and birds respiratory disease and preparation method thereof "; illustrative instead of determinate; several examples can be enumerated according to institute's limited range; because of a little; in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (4)
1. one kind for preventing and treating the Chinese veterinary drug preparation of livestock and birds respiratory disease, it is characterized in that, its Chinese herbal medicine mixed preparing pressing row parts by weight proportioning forms: Flos Daturae 8-15 part, Herba Ephedrae 8-15 part, Semen Armeniacae Amarum (parched) 7-14 part, Semen Raphani 6-13 part, Herba Artemisiae Annuae 6-11 part, sky Radix Linderae 6-11 part, Radix Stephaniae Tetrandrae 6-9 part, Herba Taraxaci 4-5 part, Radix Et Rhizoma Rhei 3-5 part, Radix Glycyrrhizae 3-5 part.
2. described in a claim 1 for preventing and treating the preparation method of the Chinese veterinary drug preparation of livestock and birds respiratory disease, it is characterized in that, carry out according to the following steps: the first coarse powder of every taste Chinese crude drug is to 20-40 order, rear low temperature rapid draing, pulverize at low temperature crosses 200-500 mesh sieve, pulverize at low temperature crosses 1000 mesh sieves again, for subsequent use; Take according to each taste Chinese medicine number in prescription is enough, add in blender and stir 20-30 minute, packaging, to obtain final product.
3., as claimed in claim 2 for preventing and treating the preparation method of the Chinese veterinary drug preparation of livestock and birds respiratory disease, its prescription is as follows:
1. all plant crosses 1000 mesh sieves, and particle diameter reaches 12.5um;
2. moisture content is less than 5%;
3. consumption is the 1/5-1/3 of 80 order coarse powder;
4. bioavailability is not less than 99%.
4. as claimed in claim 1 for preventing and treating the Chinese veterinary drug preparation of livestock and birds respiratory disease, it is suitable for following disease: cattle and sheep contagious pleuropneumonia, cattle and sheep hemorrhagic septicemia, mycoplasma pneumoniae of swine, porcine contagious pleuropneumonia, pig lung plague, atrophic rhinitis, circovirus disease, reproductive and respiratory syndrome, the respiratory tract diseases such as chicken and duck chronic respiratory tract disease, infectious laryngotracheitis of chicken, infectious bronchitis of chicken.
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| CN105168444B (en) * | 2015-10-10 | 2019-02-19 | 湖北武当动物药业有限责任公司 | One kind is for preventing and treating livestock and poultry respiratory syndrome drug |
| CN105998282A (en) * | 2016-05-27 | 2016-10-12 | 施瑞客（天津）生物技术有限公司 | Traditional Chinese medicinal composition for treating contagious bovine pleuropneumonia in cows and preparation method of traditional Chinese medicinal composition |
| CN107281348A (en) * | 2017-05-27 | 2017-10-24 | 江西合盈生物科技有限公司 | A kind of thousand mesh Chinese medicine preparations and preparation method, quality standard for being used to prevent and treat livestock and poultry cough and asthma syndrome |
| CN108888690A (en) * | 2018-06-29 | 2018-11-27 | 广西万寿谷投资集团股份有限公司 | A kind of feed addictive and preparation method thereof for preventing and treating infectious bronchitis |
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| CN100546606C (en) * | 2007-06-06 | 2009-10-07 | 中国农业大学 | A kind of medicine of preventing and treating fowl's respiratory tract diseases and preparation method thereof that is used to |
| CN101181496B (en) * | 2007-11-16 | 2011-02-16 | 河北农业大学 | Medicament for preventing and controlling infectious bronchitis |
| CN102091178B (en) * | 2009-12-15 | 2012-05-30 | 天津中敖生物科技有限公司 | Traditional Chinese medicine composite for treating respiratory disease and preparation method thereof |
| CN101810699A (en) * | 2009-12-17 | 2010-08-25 | 河南省康星药业有限公司 | Preparation method of Maxingshigan submicron powder |
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