CN113539356A - Targeted health management method for determining prevention and treatment targets by using gene detection - Google Patents
Targeted health management method for determining prevention and treatment targets by using gene detection Download PDFInfo
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- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 43
- 238000001514 detection method Methods 0.000 title claims abstract description 39
- 230000036541 health Effects 0.000 title claims abstract description 25
- 238000007726 management method Methods 0.000 title claims abstract description 25
- 230000002265 prevention Effects 0.000 title claims abstract description 24
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 64
- 210000000078 claw Anatomy 0.000 claims abstract description 24
- 230000007246 mechanism Effects 0.000 claims abstract description 24
- 230000008685 targeting Effects 0.000 claims abstract description 13
- 238000005070 sampling Methods 0.000 claims description 7
- 239000008280 blood Substances 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 5
- 230000033228 biological regulation Effects 0.000 claims description 3
- 238000007405 data analysis Methods 0.000 claims description 3
- 238000002372 labelling Methods 0.000 claims description 3
- 239000010902 straw Substances 0.000 claims description 3
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- 238000003825 pressing Methods 0.000 claims 1
- 230000009471 action Effects 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 9
- 230000001105 regulatory effect Effects 0.000 abstract 3
- 238000007789 sealing Methods 0.000 description 9
- 230000005540 biological transmission Effects 0.000 description 3
- 230000006378 damage Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
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- 206010028980 Neoplasm Diseases 0.000 description 1
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- 210000003437 trachea Anatomy 0.000 description 1
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- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/30—Drug targeting using structural data; Docking or binding prediction
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Abstract
The invention provides a targeting health management method for determining a prevention and treatment target by using gene detection, and relates to the technical field of gene detection. The targeting health management method for determining the prevention and treatment target by using gene detection comprises a storage box, wherein a loading mechanism is installed in the storage box, the loading mechanism comprises a turntable, and a support rod is connected with the internal thread of a nut. The targeting health management method for determining the prevention and treatment target by utilizing gene detection comprises the steps that a regulating rod drives a magnetic block to move, when the magnetic block moves to a desired position, the regulating rod is loosened, the regulating rod drives a clamping rod to be clamped in a clamping groove under the action of a spring, meanwhile, a driving shaft drives a driving claw to rotate, the driving claw drives a turntable to rotate, when a positioning block rotates to the position of the magnetic block, the magnetic block limits the rotation of the turntable, the driving shaft drives the driving claw to swing at the moment, and then the driving claw and the turntable are matched for use, so that the effects of automatically positioning a reagent bottle and being convenient to sample are achieved.
Description
Technical Field
The invention relates to the technical field of gene detection, in particular to a targeting health management method for determining a prevention and treatment target by using gene detection.
Background
Modern medical research proves that almost all diseases are related to genes except for injuries, gene detection is very important for guiding cancer treatment, the gene detection is a technology for detecting DNA through blood, other body fluids or cells, after the peripheral venous blood or other tissue cells of a detected person are taken and the gene information is amplified, DNA molecular information in the cells of the detected person is detected through specific equipment, and various conditions of the genes contained in the DNA molecular information are analyzed, so that people can know the gene information of themselves, determine the etiology or predict the risk of the body suffering from certain diseases, samples and reagents for gene detection are stored in a constant-temperature sterile environment, the existing detection device has poor sealing effect, the internal environment of the device can be damaged when the reagents or samples are accessed, the storage effect is poor, and the existing device can only store reagent bottles with fixed specifications, when reagent bottles with various specifications need to be stored, the reagent bottles need to be stored in different devices, and the reagent bottles are inconvenient to use.
Aiming at the defects of the prior art, the invention provides a targeting health management method for determining a prevention and treatment target by using gene detection, which has the advantages of preventing the internal environment of the device from being damaged, having high storage quality, automatically positioning reagent bottles, being convenient to take samples, automatically adjusting storage radius, having wide application range and the like, and solves the problems that the existing detection device has poor sealing effect, can damage the internal environment of the device when storing and taking reagents, has poor storage effect, can only store reagent bottles with fixed specifications, and is inconvenient to use because reagent bottles with various specifications need to be stored in different devices.
Disclosure of Invention
In order to prevent the internal environment of the device from being damaged, achieve high storage quality, automatically position the reagent bottle, take a sample conveniently, automatically adjust the storage radius and achieve the purpose of wide application range, the invention is realized by the following technical scheme: a targeted health management device for determining prevention and treatment targets by using gene detection comprises a storage box, the storage box is internally provided with a carrying mechanism which comprises a rotary disc, the rotary disc is fixedly connected with the inner bottom of the storage box, a suction pipe is welded at the bottom of the rotary table, an air valve is hinged at the bottom of the suction pipe, a connecting rod is hinged at the top of the air valve, the top of the connecting rod is hinged with a bottom rod, the outer side of the rotating disc is welded with a positioning block, the inside of the rotating disc is inserted with a driving shaft, a driving claw is hinged on the outer side of the driving shaft, a clamping wheel is fixedly connected inside the rotary table, the front surface of the clamping wheel is engaged with a bevel gear, the inside of the bevel gear is fixedly connected with a limiting bag, the inner wall of the bevel gear is connected with a clamping block in a sliding mode, the inside of the bevel gear is connected with a nut in a clamping mode, and the inside of the nut is connected with a supporting rod in a threaded mode.
Furthermore, a carrying groove is formed in the turntable, positioning blocks correspond to the outer sides of each carrying groove, and the positions of the positioning blocks are in a step shape.
Furthermore, branch sliding connection is in the inside of carousel, and branch is close to one side fixedly connected with gyro wheel at year thing groove center.
Further, still include sealed chamber, sealed chamber sets up in the inside of storage box, it has access mechanism to peg graft at the top in sealed chamber, it carries thing mechanism to peg graft in the interior bottom in sealed chamber, the left side sliding connection of storage box has the magnetic path, the left side sliding connection of magnetic path has the regulation pole, the interior bottom sliding connection of sealed chamber has the connecting pipe, the inside sliding connection of connecting pipe has the ejector pin.
Furthermore, a clamping rod is welded on the right side of the adjusting rod.
Furthermore, the storing and taking mechanism comprises a temperature control pipe, the temperature control pipe is inserted at the top of the sealed cavity, the inside of the temperature control pipe is connected with a support in a sliding manner, the top of the support is hinged with a swing door, the bottom of the support is inserted with a rotating wheel, the inner wall of the support is hinged with a pusher dog, the inside of the support is fixedly connected with an electromagnet, the inside of the electromagnet is connected with a stop block in a sliding manner, the inside of the rotating wheel is connected with a screw rod in a threaded manner, the inner wall of the support is inserted with a scroll, the inner wall of the support is connected with a clamping rod in a sliding manner, one side of the clamping rod, far away from the scroll, is fixedly connected with an air bag, the bottom of the temperature control pipe is connected with a temperature control plate in a sliding manner, the inside of the temperature control plate is connected with an air pressure plate in a sliding manner, one side of the air pressure plate, close to the inside of the temperature control plate, is hinged with a gear, the inside of the gear is inserted with a driving wheel, the outer side of the driving wheel is hinged with a driving claw.
Furthermore, the middle position of the feeler lever is hinged inside the temperature control plate, and meanwhile, control switches inside the temperature control plate are respectively positioned on two sides of the top of the feeler lever.
A targeted health management method for determining prevention and treatment targets by using gene detection comprises the following steps:
s1, extracting cells or blood of the detected person by using a sampler, storing the sample in a reagent bottle, and labeling the reagent bottle;
s2, inserting the reagent bottle into the bracket, and swinging the door to keep the bracket sealed;
s3, simultaneously, the temperature control plate starts the heater or the cooler through the difference between the internal temperature of the bracket and the internal temperature of the sealing cavity;
s4, opening the temperature control plate, inserting the reagent bottle into the carrying groove in the turntable, and storing the reagent bottle;
s5, after the storage is finished, the storage box is taken to a detection chamber for gene detection;
s6, moving the adjusting rod and the magnetic block, and then selecting a sample to be extracted through the magnetic block and the positioning block;
s7, starting a motor, descending the support through the screw rod, and fixing the sampling reagent bottle through the clamping rod by the support;
s8, taking out the sampling reagent bottle by the support through the screw, closing the temperature control plate, keeping the storage box sealed, and taking out the reagent bottle;
s9, after the reagent bottle is taken out, adding a detection reagent into the bottle, placing the bottle below a gene chip for gene detection, and recording the detection result;
s10, according to the steps S6-S9, detecting a plurality of samples and completing data analysis.
Compared with the prior art, the invention has the following beneficial effects:
1. the targeting health management method for determining the prevention and treatment target by using gene detection comprises the steps of closing a support by swinging a swing door, sealing a temperature control tube by the support, enabling a control switch on the left side to be electrified by the contact rod when the temperature in the temperature control tube is lower than the temperature in a sealing cavity, enabling the thrust of an air pressure plate at the bottom of the temperature control plate to be larger than the thrust of an air pressure plate at the top, enabling a contact rod to be pushed by the air pressure plate at the bottom to swing by the air pressure plate at the top, enabling a control switch on the left side to be electrified by the contact rod, enabling a heater to enable the temperature in the temperature control tube to be increased by the heater, enabling the contact rod to be kept horizontal under the action of the air pressure plate when the temperature is increased to be the same as the temperature in the sealing cavity, enabling the control switch to be powered off, enabling a driving wheel to rotate by the driving wheel to drive a driving claw to rotate, enabling the temperature control tube to be communicated with the sealing cavity under the action of a tooth socket, and enabling the temperature control tube to be communicated with the sealing cavity when the temperature control plate is moved to the rightmost side, the action wheel drives the swing of drive claw, and the drive claw makes the temperature control board can not reset, and the screw rod rotates under the effect of motor simultaneously, and the screw rod rotates and drives the runner decline, and the runner drives the support and descends, and rethread support uses with the cooperation of clamping bar to the effect that can prevent device internal environment from destroying, storage quality is high has been reached.
2. The targeting health management method for determining the prevention and treatment target by utilizing gene detection comprises the steps that an adjusting rod is pulled to slide leftwards, the adjusting rod drives a clamping rod to be far away from a clamping groove, the adjusting rod is moved at the moment, the adjusting rod drives a magnetic block to move, when the magnetic block moves to a desired position, the adjusting rod is loosened, the adjusting rod drives the clamping rod to be clamped in the clamping groove under the action of a spring, meanwhile, a driving shaft drives a driving claw to rotate, the driving claw drives a rotary plate to rotate, the rotary plate drives a positioning block to rotate, when the positioning block rotates to the position of the magnetic block, the magnetic block limits the rotary plate to rotate, the driving shaft drives the driving claw to swing at the moment, and the driving claw and the rotary plate are matched for use, so that the effect of automatically positioning a reagent bottle and convenient sampling is achieved.
3. According to the targeting health management method for determining the prevention and treatment target by utilizing gene detection, the bevel gear is driven to rotate by the rotation of the clamping wheel, the bevel gear drives the nut to rotate through the clamping block, the nut drives the supporting rod to move, the supporting rod drives the roller to move, when the supporting rod moves to a certain position, the supporting rod stops moving under the action of the spring, the supporting rod limits the nut to rotate, the nut pushes the clamping block to slide, the clamping block extrudes the limiting bag, and then the limiting bag is matched with the air bag to use, so that the effect of automatically adjusting the storage radius is achieved, and the method is suitable for a wide range.
Drawings
FIG. 1 is a schematic view of the present invention;
FIG. 2 is an enlarged view of part A of FIG. 1;
FIG. 3 is a schematic view of a portion of the structural carrier mechanism of the present invention;
FIG. 4 is a schematic top cross-sectional view of the structural carrier mechanism of the present invention;
FIG. 5 is an enlarged view of portion D of FIG. 4 according to the present invention;
FIG. 6 is a partial schematic view of a structural accessor mechanism of the invention;
FIG. 7 is an enlarged view of portion B of FIG. 6 according to the present invention;
FIG. 8 is a schematic top view, partially in section, of the rotor according to the present invention;
FIG. 9 is an enlarged view of portion C of FIG. 8 according to the present invention;
FIG. 10 is a partial schematic view of a temperature control plate of the present invention.
In the figure: 1. a storage box; 2. sealing the cavity; 3. an access mechanism; 31. a temperature control tube; 32. a support; 33. a swing door; 34. a rotating wheel; 35. a pusher dog; 36. an electromagnet; 37. a stopper; 38. a screw; 39. a reel; 310. a clamping bar; 311. an air bag; 312. a temperature control plate; 313. a gas pressure plate; 314. a feeler lever; 315. a gear; 316. a driving wheel; 317. a driving claw; 4. a carrying mechanism; 41. a turntable; 42. a straw; 43. an air valve; 44. a connecting rod; 45. a bottom bar; 46. positioning blocks; 47. a drive shaft; 48. a driving pawl; 49. a pinch wheel; 410. a bevel gear; 411. a limiting bag; 412. a clamping block; 413. a nut; 414. a strut; 5. a magnetic block; 6. adjusting a rod; 7. a connecting pipe; 8. and a push rod.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The embodiment of the targeting health management method for determining the prevention and treatment target by using gene detection is as follows:
example one
Referring to fig. 1-5, a targeting health management device for determining a prevention and treatment target by using gene detection, includes a storage box 1, a loading mechanism 4 is installed inside the storage box 1, the loading mechanism 4 includes a rotary table 41, loading slots are opened inside the rotary table 41, a positioning block 46 is correspondingly arranged outside each loading slot, the positioning block 46 is in a step shape, the rotary table 41 is fixedly connected to the inner bottom of the storage box 1, a suction pipe 42 is welded to the bottom of the rotary table 41, an air valve 43 is hinged to the bottom of the suction pipe 42, a connecting rod 44 is hinged to the top of the air valve 43, a bottom rod 45 is hinged to the top of the connecting rod 44, a positioning block 46 is welded to the outside of the rotary table 41, a driving shaft 47 is inserted into the rotary table 41, a driving claw 48 is hinged to the outside of the driving shaft 47, a clamping wheel 49 is fixedly connected to the inside of the rotary table 41, a bevel gear 410 is engaged with the front surface of the clamping wheel 49, spacing bag 411 of the inside fixedly connected with of bevel gear 410, bevel gear 410's inner wall sliding connection has fixture block 412, bevel gear 410's inside joint has nut 413, nut 413's inside threaded connection has branch 414, branch 414 sliding connection is in the inside of carousel 41, and branch 414 is close to one side fixedly connected with gyro wheel at year thing groove center, drive shaft 47 drives driving pawl 48 and rotates, driving pawl 48 drives carousel 41 and rotates, carousel 41 drives locating piece 46 and rotates, when locating piece 46 rotates to magnetic path 5 position, magnetic path 5 restriction carousel 41 rotates, drive shaft 47 drives driving pawl 48 and swings this moment, guarantee to take out the reagent bottle of wanting.
Example two
Referring to fig. 1-10, a targeting health management device for determining a prevention and treatment target by using gene detection, comprising a storage box 1, and further comprising a sealed cavity 2, wherein the sealed cavity 2 is arranged inside the storage box 1, the top of the sealed cavity 2 is inserted with an access mechanism 3, the access mechanism 3 comprises a temperature control tube 31, the temperature control tube 31 is inserted at the top of the sealed cavity 2, the temperature control tube 31 is connected with a support 32 in a sliding manner, the top of the support 32 is hinged with a swing door 33, the bottom of the support 32 is inserted with a rotating wheel 34, the inner wall of the support 32 is hinged with a pusher dog 35, the support 32 is fixedly connected with an electromagnet 36 in the interior, the electromagnet 36 is connected with a stopper 37 in a sliding manner, the inner thread of the rotating wheel 34 is connected with a screw 38, the inner wall of the support 32 is inserted with a scroll 39, the inner wall of the support 32 is connected with a clamping bar 310 in a sliding manner, one side of the clamping bar 310 far away from the scroll 39 is fixedly connected with an airbag 311, the bottom of the temperature control tube 31 is slidably connected with a temperature control plate 312, the inside of the temperature control plate 312 is slidably connected with an air pressure plate 313, one side of the air pressure plate 313 close to the inside of the temperature control plate 312 is hinged with a touch rod 314, the middle position of the touch rod 314 is hinged in the inside of the temperature control plate 312, meanwhile, a control switch in the inside of the temperature control plate 312 is respectively positioned at two sides of the top of the touch rod 314, the top of the temperature control plate 312 is fixedly connected with a gear 315, a driving wheel 316 is inserted in the inside of the gear 315, the outer side of the driving wheel 316 is hinged with a driving claw 317, the screw 38 rotates forward under the action of the motor, the rotating wheel 34 cannot rotate under the action of the poking claw 35, the screw 38 rotates forward to drive the rotating wheel 34 to descend, the rotating wheel 34 drives the support 32 to descend, the support 32 drives the reagent bottle to be inserted in the loading slot, and the reagent bottle is automatically stored.
EXAMPLE III
Referring to fig. 1-10, a targeting health management device for determining a prevention and treatment target by using gene detection, comprising a storage box 1, and further comprising a sealed cavity 2, wherein the sealed cavity 2 is arranged inside the storage box 1, the top of the sealed cavity 2 is inserted with an access mechanism 3, the access mechanism 3 comprises a temperature control tube 31, the temperature control tube 31 is inserted at the top of the sealed cavity 2, the temperature control tube 31 is connected with a support 32 in a sliding manner, the top of the support 32 is hinged with a swing door 33, the swing door 33 swings back through a spring to enable the support 32 to be automatically closed, the bottom of the support 32 is inserted with a rotating wheel 34, the inner wall of the support 32 is hinged with a pusher dog 35, the inside of the support 32 is fixedly connected with an electromagnet 36, the inside of the electromagnet 36 is connected with a stop 37 in a sliding manner, the inside of the rotating wheel 34 is connected with a screw 38 through a screw, the inner wall of the support 32 is inserted with a scroll 39, the scroll 39 is in transmission connection with the rotating wheel 34 through a transmission belt, the scroll 39 is connected with the clamping rod 310 through a rolling rope in a transmission way, the inner wall of the bracket 32 is connected with the clamping rod 310 in a sliding way, one side of the clamping rod 310 far away from the scroll 39 is fixedly connected with an air bag 311, the bottom of the temperature control tube 31 is connected with a temperature control plate 312 in a sliding way, a spring is welded at the right side of the temperature control plate 312 and is used for resetting, an air pressure plate 313 is connected in the temperature control plate 312 in a sliding way, one side of the air pressure plate 313 close to the inside of the temperature control plate 312 is hinged with a touch rod 314, the middle position of the touch rod 314 is hinged in the temperature control plate 312, meanwhile, a control switch in the temperature control plate 312 is respectively positioned at two sides of the top of the touch rod 314, gears 315 are fixedly connected with the top of the temperature control plate 312, a driving wheel 316 is inserted in the gear 315, a driving claw 317 is hinged at the outer side of the driving wheel 316, a carrying mechanism 4 is inserted in the inner bottom of the sealed cavity 2, the carrying mechanism 4 comprises a turntable 41, carrying grooves are formed in the turntable 41, and the outer side of each carrying groove is corresponding to a positioning block 46, meanwhile, the positioning blocks 46 are in a step shape, the rotary table 41 is fixedly connected to the inner bottom of the storage box 1, a suction pipe 42 is welded at the bottom of the rotary table 41, the suction pipe 42 is connected with a limiting bag 411 through an air pipe, an air valve 43 is hinged at the bottom of the suction pipe 42, a connecting rod 44 is hinged at the top of the air valve 43, a bottom rod 45 is hinged at the top of the connecting rod 44, the positioning block 46 is welded at the outer side of the rotary table 41, a driving shaft 47 is inserted in the rotary table 41, a driving claw 48 is hinged at the outer side of the driving shaft 47, a clamping wheel 49 is fixedly connected in the rotary table 41, a bevel gear 410 is meshed at the front surface of the clamping wheel 49, the limiting bag 411 is fixedly connected in the bevel gear 410, a clamping block 412 is slidably connected to the inner wall of the bevel gear 410, a nut 413 is clamped in the bevel gear 410, a supporting rod 414 is connected in the inner thread of the nut 413, the supporting rod 414 is slidably connected in the rotary table 41, and a roller wheel is fixedly connected to one side of the supporting rod 414 close to the center of the loading groove, the left side sliding connection of storage box 1 has magnetic path 5, and the left side sliding connection of magnetic path 5 has regulation pole 6, and the right side welding of adjusting pole 6 has the kelly, and the interior bottom sliding connection of sealed chamber 2 has connecting pipe 7, and connecting pipe 7 is connected with gasbag 311 through the trachea, and the inside sliding connection of connecting pipe 7 has ejector pin 8.
A targeted health management method for determining prevention and treatment targets by using gene detection comprises the following steps:
s1, extracting cells or blood of the detected person by using a sampler, storing the sample in a reagent bottle, and labeling the reagent bottle;
s2, inserting the reagent bottle into the rack 32, and swinging the door 33 to keep the rack 32 sealed;
s3, simultaneously, the temperature control plate 312 starts the heater or the cooler through the difference between the internal temperature of the bracket 32 and the internal temperature of the sealed cavity 2;
s4, opening the temperature control plate 312, inserting the reagent bottles into the carrying grooves in the turntable 41, and storing the reagent bottles;
s5, after the storage is finished, the storage box is taken to a detection chamber for gene detection;
s6, moving the adjusting rod 6 and the magnetic block 5, and then selecting a sample to be extracted through the magnetic block 5 and the positioning block 46;
s7, starting a motor, descending the bracket 32 through the screw 38, and fixing the sampling reagent bottle by the bracket 32 through the clamping rod 310;
s8, taking out the sampling reagent bottle by the bracket 32 through the screw 38, closing the temperature control plate 312, keeping the storage box 1 sealed, and taking out the reagent bottle;
s9, after the reagent bottle is taken out, adding a detection reagent into the bottle, placing the bottle below a gene chip for gene detection, and recording the detection result;
s10, according to the steps S6-S9, detecting a plurality of samples and completing data analysis.
When the reagent bottle rack is used, a reagent bottle is inserted into the rack 32, the reagent bottle drives the swing door 33 to swing downwards, meanwhile, the reagent bottle pushes the clamping rod 310 to slide towards the outer side of the rack 32, the clamping rod 310 descends under the action of a spring to fix the reagent bottle, the clamping rod 310 increases the air pressure inside the air bag 311, the air bag 311 reduces the air pressure inside the limiting bag 411 through the connecting pipe 7 and the suction pipe 42, at the moment, the clamping wheel 49 rotates to drive the bevel gear 410 to rotate, the bevel gear 410 drives the nut 413 to rotate through the clamping block 412, the nut 413 drives the supporting rod 414 to move, the supporting rod 414 drives the roller to move, when the supporting rod 414 moves to a certain position, the supporting rod 414 stops moving under the action of the spring, the nut 414 limits the rotation of the nut 413, the clamping block 412 pushes the clamping block 412 to slide, the clamping block 412 extrudes the limiting bag 411, the radius of the reagent bottle is smaller, the larger air pressure inside the limiting bag 411 is, the longer the moving distance of the supporting rod 414 is, the smaller the storage radius of the carrying groove is smaller, the reagent bottle can be ensured to be just stored in the carrying groove and not to shake, at this time, the swing door 33 swings back under the action of the spring to close the support 32, the support 32 enables the temperature control tube 31 to be sealed, when the internal temperature of the temperature control tube 31 is lower than the internal temperature of the sealed cavity 2, the thrust of the air pressure plate 313 at the bottom of the temperature control plate 312 is larger than that of the air pressure plate 313 at the top, the air pressure plate 313 at the bottom pushes the contact rod 314 to swing, the contact rod 314 enables the control switch at the left side to be electrified, the control switch at the left side enables the heater to be started, the temperature inside the temperature control tube 31 is increased by the heater, when the temperature is increased to be the same as that in the sealed cavity 2, the contact rod 314 is kept horizontal under the action of the air pressure plate 313, the control switch is powered off, at this time, the driving wheel 316 is powered on and rotates, the driving wheel 316 drives the driving pawl 317 to rotate, the driving pawl drives the gear 315 to rotate, the temperature control plate 312 to slide rightwards under the action of the tooth groove 317, the temperature control plate 312 connects the temperature control tube 31 with the sealed cavity 2, when the temperature control plate 312 moves to the rightmost side, the driving wheel 316 drives the driving claw 317 to swing, the driving claw 317 prevents the temperature control plate 312 from resetting, at the same time, the screw 38 rotates forward under the action of the motor, at this time, the rotating wheel 34 does not rotate under the action of the pusher dog 35, the screw 38 rotates forward to drive the rotating wheel 34 to descend, the rotating wheel 34 drives the support 32 to descend, the support 32 descends to drive the reagent bottle to descend, the reagent bottle is inserted in the loading slot, the reagent bottle drives the bottom rod 45 to descend, the bottom rod 45 drives the connecting rod 44 to descend, the connecting rod 44 drives the air valve 43 to close, the air valve 43 keeps the air pressure inside the spacing bag 411 stable without influencing the storage of the reagent bottle, at this time, the screw 38 rotates backward, the screw 38 drives the rotating wheel 34 to rotate backward, the rotating wheel 34 drives the pusher dog 35 to swing, the rotating wheel 34 drives the scroll 39 to rotate, the scroll 39 drives the clamping rod 310 to keep away from the reagent bottle through the rope, when the rod clamping rod 310 moves to the inner wall of the bracket 32, the rotating wheel 34 stops rotating under the action of the clamping rod 310, the screw 38 drives the rotating wheel 34 to ascend, the rotating wheel 34 drives the bracket 32 to ascend, the reagent bottle storage is completed, the equipment is powered off, the temperature control plate 312 is reset under the action of the spring, the temperature control plate 312 enables the temperature control tube 31 not to be communicated with the sealed cavity 2, the next use is not influenced, when the reagent bottle needs to be taken out, the adjusting rod 6 is pulled to slide leftwards, the adjusting rod 6 drives the clamping rod to be away from the clamping groove, at the moment, the adjusting rod 6 is moved, the adjusting rod 6 drives the magnetic block 5 to move, when the magnetic block 5 moves to a desired position, the adjusting rod 6 is loosened, the adjusting rod 6 drives the clamping rod to be clamped in the clamping groove under the action of the spring, meanwhile, the driving shaft 47 drives the driving claw 48 to rotate, the driving claw 48 drives the rotating disc 41 to rotate, the rotating disc 41 drives the positioning block 46 to rotate, when the positioning block 46 rotates to the position of the magnetic block 5, magnet 5 restricts the carousel 41 and rotates, drive shaft 47 drives the swing of drive pawl 48 this moment, guarantee to take out the reagent bottle of desire, screw 38 corotation this moment drives support 32 and descends, support 32 descends and drives clamping bar 310 cup joint in the reagent bottle outside, then screw 38 reversal, make electro-magnet 36 circular telegram through the switch simultaneously, electro-magnet 36 drives dog 37 and is close to pusher dog 35, dog 37 restricts the swing of pusher dog 35, screw 38 reversal directly drives runner 34 and rises this moment, runner 34 drives support 32 and rises, support 32 drives the reagent bottle and rises, when support 32 rises to the top, the equipment cuts off the power supply, temperature control plate 312 resets, it can to take out the reagent bottle this moment.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. A targeted health management device for determining a control target using gene testing, comprising a storage case (1), characterized in that: the inside mounting of storage box (1) has year thing mechanism (4), it includes carousel (41) to carry thing mechanism (4), carousel (41) fixed connection is at the interior bottom of storage box (1), the bottom welding of carousel (41) has straw (42), the bottom of straw (42) articulates there is pneumatic valve (43), the top of pneumatic valve (43) articulates there is connecting rod (44), the top of connecting rod (44) articulates there is sill bar (45), the outside welding of carousel (41) has locating piece (46), the inside grafting of carousel (41) has drive shaft (47), the outside of drive shaft (47) articulates there is drive pawl (48), the inside fixedly connected with of carousel (41) presss from both sides tight wheel (49), the front meshing of pressing from both sides tight wheel (49) has bevel gear (410), the inside fixedly connected with spacing bag (411) of bevel gear (410), the inner wall of the bevel gear (410) is connected with a clamping block (412) in a sliding mode, a nut (413) is clamped inside the bevel gear (410), and a support rod (414) is connected to the inner thread of the nut (413) in a threaded mode.
2. The targeted health management device for determining prevention and treatment goals using gene testing of claim 1, wherein: the inside of carousel (41) has been seted up and has been carried the thing groove, and the outside of every group year thing groove all corresponds locating piece (46), and the position of locating piece (46) is the echelonment simultaneously.
3. The targeted health management device for determining prevention and treatment goals using gene testing of claim 1, wherein: the supporting rod (414) is connected inside the rotating disc (41) in a sliding mode, and one side, close to the center of the loading groove, of the supporting rod (414) is fixedly connected with a roller.
4. The targeted health management device for determining prevention and treatment goals using gene testing of claim 1, wherein: still include sealed chamber (2), the inside at storage box (1) is seted up in sealed chamber (2), it has access mechanism (3) to peg graft at the top of sealed chamber (2), the interior bottom grafting of sealed chamber (2) has year thing mechanism (4), the left side sliding connection of storage box (1) has magnetic path (5), the left side sliding connection of magnetic path (5) has regulation pole (6), the interior bottom sliding connection of sealed chamber (2) has connecting pipe (7), the inside sliding connection of connecting pipe (7) has ejector pin (8).
5. The targeted health management device for determining prevention and treatment goals using gene testing of claim 4, wherein: the right side of the adjusting rod (6) is welded with a clamping rod.
6. The targeted health management device for determining prevention and treatment goals using gene testing of claim 4, wherein: the storing and taking mechanism (3) comprises a temperature control pipe (31), the temperature control pipe (31) is inserted at the top of the sealed cavity (2), the inside of the temperature control pipe (31) is connected with a support (32) in a sliding manner, the top of the support (32) is hinged with a swing door (33), the bottom of the support (32) is inserted with a rotating wheel (34), the inner wall of the support (32) is hinged with a pusher dog (35), the inside of the support (32) is fixedly connected with an electromagnet (36), the inside of the electromagnet (36) is connected with a stop block (37) in a sliding manner, the inside of the rotating wheel (34) is connected with a screw rod (38) in a threaded manner, the inner wall of the support (32) is inserted with a scroll (39), the inner wall of the support (32) is connected with a clamping rod (310) in a sliding manner, one side of the clamping rod (310) far away from the scroll (39) is fixedly connected with an air bag (311), and the bottom of the temperature control pipe (31) is connected with a temperature control plate (312) in a sliding manner, the temperature control device is characterized in that an air pressure plate (313) is connected to the inside of the temperature control plate (312) in a sliding mode, a touch rod (314) is hinged to one side, close to the inside of the temperature control plate (312), of the air pressure plate (313), a gear (315) is fixedly connected to the top of the temperature control plate (312), a driving wheel (316) is inserted into the inside of the gear (315), and a driving claw (317) is hinged to the outer side of the driving wheel (316).
7. The targeted health management device for determining prevention and treatment goals using gene testing of claim 6, wherein: the middle position of the feeler lever (314) is hinged inside the temperature control plate (312), and meanwhile, control switches inside the temperature control plate (312) are respectively positioned on two sides of the top of the feeler lever (314).
8. The targeted health management method for targeting prevention and treatment using gene testing of claim 1, comprising the steps of:
s1, extracting cells or blood of the detected person by using a sampler, storing the sample in a reagent bottle, and labeling the reagent bottle;
s2, inserting the reagent bottle into the bracket (32), and swinging the door (33) to keep the bracket (32) closed;
s3, simultaneously controlling the temperature control board (312) to start the heater or the cooler through the difference between the internal temperature of the bracket (32) and the internal temperature of the sealed cavity (2);
s4, opening the temperature control plate (312), inserting the reagent bottles into the carrying groove in the turntable (41), and storing the reagent bottles;
s5, after the storage is finished, the storage box is taken to a detection chamber for gene detection;
s6, moving the adjusting rod (6) and the magnetic block (5), and then selecting a sample to be extracted through the magnetic block (5) and the positioning block (46);
s7, starting a motor, enabling the bracket (32) to descend through the screw (38), and fixing the sampling reagent bottle through the clamping rod (310) by the bracket (32);
s8, taking out the sampling reagent bottle by the bracket (32) through the screw (38), closing the temperature control plate (312), keeping the storage box (1) sealed, and taking out the reagent bottle;
s9, after the reagent bottle is taken out, adding a detection reagent into the bottle, placing the bottle below a gene chip for gene detection, and recording the detection result;
s10, according to the steps S6-S9, detecting a plurality of samples and completing data analysis.
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| CN116331664A (en) * | 2023-02-10 | 2023-06-27 | 山东大学 | Kit and method for detecting breast cancer tumor markers |
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