CN113539356B - Targeting health management method for determining control target by utilizing gene detection - Google Patents
Targeting health management method for determining control target by utilizing gene detection Download PDFInfo
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- CN113539356B CN113539356B CN202110929901.9A CN202110929901A CN113539356B CN 113539356 B CN113539356 B CN 113539356B CN 202110929901 A CN202110929901 A CN 202110929901A CN 113539356 B CN113539356 B CN 113539356B
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- 238000001514 detection method Methods 0.000 title claims abstract description 37
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 34
- 230000036541 health Effects 0.000 title claims abstract description 18
- 230000008685 targeting Effects 0.000 title claims description 9
- 238000007726 management method Methods 0.000 title abstract description 18
- 210000000078 claw Anatomy 0.000 claims abstract description 27
- 230000007246 mechanism Effects 0.000 claims abstract description 24
- 230000002265 prevention Effects 0.000 claims abstract description 4
- 238000007789 sealing Methods 0.000 claims description 26
- 239000010902 straw Substances 0.000 claims description 7
- 238000003466 welding Methods 0.000 claims description 7
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 54
- 230000009471 action Effects 0.000 abstract description 20
- 230000000694 effects Effects 0.000 abstract description 9
- 238000005070 sampling Methods 0.000 abstract description 8
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 238000007405 data analysis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000003781 tooth socket Anatomy 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
Classifications
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/30—Drug targeting using structural data; Docking or binding prediction
Abstract
The invention provides a targeted health management method for determining a control target by utilizing gene detection, and relates to the technical field of gene detection. The targeted health management method for determining the prevention and treatment target by utilizing gene detection comprises a storage box, wherein a carrying mechanism is arranged in the storage box and comprises a turntable, and a supporting rod is connected with the inner thread of a nut. According to the targeted health management method for determining the control target by utilizing gene detection, the magnetic block is driven to move through the adjusting rod, when the magnetic block moves to a desired position, the adjusting rod is loosened, the adjusting rod drives the clamping rod to be clamped in the clamping groove under the action of the spring, meanwhile, the driving shaft drives the driving claw to rotate, the driving claw drives the rotary table to rotate, when the positioning block rotates to the position of the magnetic block, the magnetic block limits the rotary table to rotate, at the moment, the driving shaft drives the driving claw to swing, and the driving claw and the rotary table are matched for use, so that the effects of automatic positioning of a reagent bottle and convenience in sampling are achieved.
Description
Technical Field
The invention relates to the technical field of gene detection, in particular to a targeting health management method for determining a control target by utilizing gene detection.
Background
Modern medical research proves that almost all diseases except wounds are related to genes, the gene detection is very important for guiding cancer treatment, the gene detection is a technology for detecting DNA through blood, other body fluids or cells, peripheral venous blood or other tissue cells of a detected person are taken, after gene information of the detected person is amplified, DNA molecular information in the cells of the detected person is detected through specific equipment, and various conditions of the genes contained in the detected person are analyzed, so that people can know own gene information, clear etiology or predict the risk of a certain disease of the body, a sample and a reagent for gene detection are stored in a constant-temperature sterile environment, the sealing effect of the existing detection device is poor, the internal environment of the device is damaged when the reagent or sample is accessed, the storage effect is poor, meanwhile, the existing detection device only can store reagent bottles with fixed specifications, and when the reagent bottles with various specifications are required to be stored, the reagent bottles with different specifications are required to be stored in different devices, and the use is inconvenient.
Aiming at the defects of the prior art, the invention provides a targeting health management method for determining a control target by utilizing gene detection, which has the advantages of capability of preventing the internal environment of the device from being damaged, high storage quality, capability of automatically positioning reagent bottles, convenience in sampling, capability of automatically adjusting the storage radius, wide application range and the like, and solves the problems that the existing detection device is poor in sealing effect, can damage the internal environment of the device when carrying out reagent access, is poor in storage effect, can only store reagent bottles with fixed specifications, needs to be stored in different devices when storing reagent bottles with various specifications, and is inconvenient to use.
Disclosure of Invention
In order to realize the purposes of preventing the internal environment of the device from being damaged, having high storage quality, being capable of automatically positioning the reagent bottle, being convenient for sampling, automatically adjusting the storage radius and being applicable to a wide range, the invention is realized by the following technical scheme: the utility model provides an utilize gene detection to confirm healthy management device of targeting of prevention and cure target, includes the storage box, the internally mounted of storage box has a year thing mechanism, it includes the carousel to carry the thing mechanism, carousel fixed connection is at the interior bottom of storage box, the bottom welding of carousel has the straw, the bottom of straw articulates there is the pneumatic valve, the top of pneumatic valve articulates there is the connecting rod, the top of connecting rod articulates there is the sill bar, the outside welding of carousel has the locating piece, peg graft in the inside of carousel has the drive shaft, the outside of drive shaft articulates there is the driving pawl, the inside fixedly connected with tight pulley of carousel, the positive meshing of tight pulley has the bevel gear, the inside fixedly connected with spacing bag of bevel gear, the inner wall sliding connection of bevel gear has the fixture block, the inside joint of bevel gear has the nut, the inside threaded connection of nut has branch.
Further, the article carrying grooves are formed in the turntable, positioning blocks are respectively corresponding to the outer sides of the article carrying grooves, and meanwhile, the positioning blocks are in a step shape.
Further, branch sliding connection is in the inside of carousel, and branch is close to the one side fixedly connected with gyro wheel in year thing groove center.
Further, still include sealed chamber, sealed chamber is seted up in the inside of storage box, the top in sealed chamber is pegged graft and is had access mechanism, the interior bottom in sealed chamber is pegged graft and is had a year thing mechanism, the left side sliding connection of storage box has the magnetic path, the left side sliding connection of magnetic path has the regulation pole, the interior bottom sliding connection in sealed chamber has the connecting pipe, the inside sliding connection of connecting pipe has the ejector pin.
Further, a clamping rod is welded on the right side of the adjusting rod.
Further, access mechanism includes the temperature control pipe, the temperature control pipe is pegged graft at the top of sealed chamber, the inside sliding connection of temperature control pipe has the support, the top of support articulates there is the swing door, peg graft there is the runner bottom the support, the inner wall of support articulates there is the thumb, the inside fixedly connected with electro-magnet of support, the inside sliding connection of electro-magnet has the dog, the inside threaded connection of runner has the screw rod, peg graft there is the spool inner wall of support, the inner wall sliding connection of support has the clamping bar, one side fixedly connected with gasbag of spool is kept away from to the clamping bar, the bottom sliding connection of temperature control pipe has the temperature control board, the inside sliding connection of temperature control board has the barometer, the barometer is close to one side of temperature control board inside and articulates there is the feeler lever, the top fixedly connected with gear of temperature control board, the inside grafting of gear has the action wheel, the outside of action wheel articulates there is the initiative claw.
Further, the middle position of the feeler lever is hinged in the temperature control plate, and meanwhile, the control switches in the temperature control plate are respectively positioned on two sides of the top of the feeler lever.
A targeted health management method for determining a control target by using gene detection comprises the following steps:
s1, extracting cells or blood of a subject by using a sampler, storing a sample in a reagent bottle, and marking the reagent bottle at the same time;
s2, inserting the reagent bottle into the bracket, and keeping the bracket airtight by swinging the door;
s3, simultaneously starting a heater or a cooler by the temperature control plate through the temperature difference between the internal temperature of the bracket and the internal temperature of the sealing cavity;
s4, opening the temperature control plate, and inserting the reagent bottles into the material carrying grooves in the turntable to finish the storage of the reagent bottles;
s5, after storage is completed, the storage box is taken to a detection chamber for gene detection;
s6, moving the adjusting rod and the magnetic block, and then selecting a sample to be extracted through the magnetic block and the positioning block;
s7, starting a motor, enabling the bracket to descend through the screw rod, and fixing the sampling reagent bottle through the clamping rod by the bracket;
s8, taking out the sampling reagent bottle by the bracket through a screw, closing the temperature control plate, keeping the storage box airtight, and taking out the reagent bottle;
s9, after the reagent bottle is taken out, adding a detection reagent into the bottle, placing the reagent bottle under a gene chip, carrying out gene detection, and recording a detection result;
s10, detecting a plurality of samples according to the steps S6-S9, and completing data analysis.
Compared with the prior art, the invention has the following beneficial effects:
1. according to the targeted health management method for determining the control target by utilizing gene detection, a support is closed through swinging of a swinging door, the support enables temperature control Guan Mibi, when the temperature inside a temperature control pipe is lower than the temperature inside a sealing cavity, the thrust of an air pressure plate at the bottom of the temperature control plate is larger than that of an air pressure plate at the top of the temperature control pipe, the air pressure plate at the bottom pushes a feeler lever to swing, a control switch at the left side is powered on by the feeler lever, a heater is started by the left control switch, the temperature inside the temperature control pipe is increased by the heater, when the temperature is increased to be the same as the temperature inside the sealing cavity, the feeler lever is kept horizontal under the action of the air pressure plate, the control switch is powered off, at the moment, a driving wheel is powered on and rotates to drive a driving claw to rotate, the driving claw drives a gear to rotate under the action of a tooth socket to drive the temperature control plate to slide rightwards, when the temperature control plate moves to the rightmost side, the driving claw is driven to swing, the temperature control plate is prevented from resetting, meanwhile, a screw rotates under the action of a motor, the driving wheel drives the runner to descend, and then the support and a clamping lever are used in a matched mode, so that the internal quality of the device is prevented from being damaged.
2. According to the targeted health management method for determining the control target by utilizing gene detection, the adjusting rod is pulled to slide leftwards, the clamping rod is driven to be far away from the clamping groove by the adjusting rod, the adjusting rod is moved at the moment, the magnetic block is driven to move, the adjusting rod is loosened to enable the clamping rod to be clamped in the clamping groove under the action of the spring, meanwhile, the driving shaft drives the driving claw to rotate, the driving claw drives the turntable to rotate, the turntable drives the positioning block to rotate, when the positioning block rotates to the magnetic block position, the magnetic block limits the turntable to rotate, the driving shaft drives the driving claw to swing, and the driving claw and the turntable are matched for use, so that the effects of automatic positioning of a reagent bottle and convenience in sampling are achieved.
3. According to the targeted health management method for determining the control target by utilizing gene detection, the bevel gear is driven to rotate through rotation of the clamping wheel, the bevel gear drives the nut to rotate through the clamping block, the nut drives the supporting rod to move, the supporting rod drives the roller to move, when the supporting rod moves to a certain position, the supporting rod stops moving under the action of the spring, the supporting rod limits the nut to rotate, the clamping block is pushed to slide by the nut, the limiting bag is extruded by the clamping block, and the storage radius can be automatically adjusted through cooperation of the limiting bag and the air bag, so that the targeted health management method is suitable for a wide range of effects.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is an enlarged schematic view of portion A of FIG. 1 of the structure of the present invention;
FIG. 3 is a schematic view of a portion of a loading mechanism according to the present invention;
FIG. 4 is a schematic top cross-sectional view of the structural cargo mechanism of the present invention;
FIG. 5 is an enlarged schematic view of portion D of FIG. 4 of the structure of the present invention;
FIG. 6 is a schematic view of a portion of an access mechanism according to the present invention;
FIG. 7 is an enlarged schematic view of portion B of FIG. 6 showing the structure of the present invention;
FIG. 8 is a schematic top view in section of a portion of a structural rotor of the present invention;
FIG. 9 is an enlarged schematic view of portion C of FIG. 8 of the structure of the present invention;
FIG. 10 is a schematic view of a portion of a thermal control plate according to the present invention.
In the figure: 1. a storage box; 2. sealing the cavity; 3. an access mechanism; 31. a temperature control tube; 32. a bracket; 33. swing door; 34. a rotating wheel; 35. a pusher dog; 36. an electromagnet; 37. a stop block; 38. a screw; 39. a reel; 310. a clamping rod; 311. an air bag; 312. a temperature control plate; 313. an air pressure plate; 314. a feeler lever; 315. a gear; 316. a driving wheel; 317. a driving claw; 4. a loading mechanism; 41. a turntable; 42. a suction pipe; 43. an air valve; 44. a connecting rod; 45. a bottom bar; 46. a positioning block; 47. a drive shaft; 48. a driving claw; 49. a pinch roller; 410. bevel gears; 411. a spacing bag; 412. a clamping block; 413. a nut; 414. a support rod; 5. a magnetic block; 6. an adjusting rod; 7. a connecting pipe; 8. and (5) a push rod.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The embodiment of the targeted health management method for determining the control target by utilizing gene detection is as follows:
example 1
Referring to fig. 1-5, a targeting health management device for determining a prevention and treatment target by using gene detection comprises a storage box 1, wherein a carrying mechanism 4 is installed inside the storage box 1, the carrying mechanism 4 comprises a turntable 41, carrying grooves are formed in the turntable 41, positioning blocks 46 are respectively and correspondingly arranged on the outer sides of the carrying grooves, meanwhile, the positioning blocks 46 are in a step shape, the turntable 41 is fixedly connected to the inner bottom of the storage box 1, a suction pipe 42 is welded at the bottom of the turntable 41, an air valve 43 is hinged to the bottom of the suction pipe 42, a connecting rod 44 is hinged to the top of the air valve 43, a bottom rod 45 is hinged to the top of the connecting rod 44, a positioning block 46 is welded to the outer side of the turntable 41, a driving shaft 47 is inserted into the turntable 41, a driving claw 48 is hinged to the outer side of the driving shaft 47, a clamping wheel 49 is fixedly connected to the inner side of the turntable 41, a bevel gear 410 is meshed with the front surface of the clamping wheel 49, a limiting bag 411 is fixedly connected to the inner wall of the bevel gear 410, a clamping block 412 is connected to the inner side of the bevel gear 410 in a step-shaped manner, a supporting rod 414 is fixedly connected to the inner thread of the nut 413, the supporting rod 414 is connected to the inner side of the supporting rod 414 in a sliding manner, a supporting rod 414 is connected to the inner side of the supporting rod 414, a positioning block 414 is hinged to the bottom of the positioning block 43, a positioning block 43 is hinged to the bottom of the positioning rod 45, and a positioning block is close to the outer side of the positioning block 48 to the positioning block 48, and a magnetic block 48 is driven to the driving claw 48 to the driving magnetic block 48 to be driven to rotate, and one side of the driving claw 48 to 5 to rotate, and 5, which drives the driving claw 46 to rotate, and 5, when the driving magnetic block 46 is required to rotate 5.
Example two
Referring to fig. 1-10, a targeting health management device for determining a control target by using gene detection comprises a storage box 1, and further comprises a sealing cavity 2, wherein the sealing cavity 2 is arranged in the storage box 1, an access mechanism 3 is inserted into the top of the sealing cavity 2, the access mechanism 3 comprises a temperature control tube 31, the temperature control tube 31 is inserted into the top of the sealing cavity 2, a support 32 is slidably connected into the interior of the temperature control tube 31, a swing door 33 is hinged into the top of the support 32, a rotating wheel 34 is inserted into the bottom of the support 32, a pusher dog 35 is hinged into the inner wall of the support 32, an electromagnet 36 is fixedly connected into the interior of the support 32, a stop block 37 is slidably connected into the interior of the electromagnet 36, a screw 38 is connected into the inner wall of the support 32, a scroll 39 is inserted into the inner wall of the support 32, a clamping rod 310 is slidably connected into the inner wall of the support 32, and an airbag 311 is fixedly connected to one side of the clamping rod 310 away from the scroll 39, the bottom sliding connection of temperature control pipe 31 has temperature control board 312, the inside sliding connection of temperature control board 312 has atmospheric pressure board 313, one side that atmospheric pressure board 313 is close to temperature control board 312 inside articulates has feeler lever 314, the intermediate position of feeler lever 314 articulates in temperature control board 312's inside, the inside control switch of temperature control board 312 is located feeler lever 314 top both sides respectively simultaneously, the top fixedly connected with gear 315 of temperature control board 312, the inside grafting of gear 315 has action wheel 316, the outside of action wheel 316 articulates has initiative claw 317, screw 38 forward rotation under the effect of motor, runner 34 can not rotate under the effect of thumb 35 this moment, screw 38 forward rotation drives runner 34 and descends, runner 34 drives support 32 and descends, support 32 descends and drives the reagent bottle, the reagent bottle is pegged graft in the year thing groove, automatic storage reagent bottle.
Example III
Referring to fig. 1-10, a targeting health management device for determining a control target by using gene detection comprises a storage box 1, and further comprises a sealing cavity 2, wherein the sealing cavity 2 is arranged in the storage box 1, an access mechanism 3 is inserted at the top of the sealing cavity 2, the access mechanism 3 comprises a temperature control tube 31, the temperature control tube 31 is inserted at the top of the sealing cavity 2, a bracket 32 is slidably connected in the temperature control tube 31, a swing door 33 is hinged at the top of the bracket 32, the swing door 33 swings back through a spring, so that the bracket 32 can be automatically closed, a rotating wheel 34 is inserted at the bottom of the bracket 32, a pusher dog 35 is hinged at the inner wall of the bracket 32, an electromagnet 36 is fixedly connected in the bracket 32, a stop 37 is slidably connected in the electromagnet 36, a screw 38 is connected in the internal thread of the rotating wheel 34, a scroll 39 is inserted at the inner wall of the bracket 32, the scroll 39 is in transmission connection with the rotating wheel 34 through a transmission belt, the reel 39 is connected with the clamping rod 310 in a transmission way through a winding rope, the inner wall of the bracket 32 is connected with the clamping rod 310 in a sliding way, one side of the clamping rod 310 far away from the reel 39 is fixedly connected with the air bag 311, the bottom of the temperature control tube 31 is connected with the temperature control plate 312 in a sliding way, the right side of the temperature control plate 312 is welded with a spring for resetting, the inside of the temperature control plate 312 is connected with the air pressure plate 313 in a sliding way, one side of the air pressure plate 313 close to the inside of the temperature control plate 312 is hinged with the touch rod 314, the middle position of the touch rod 314 is hinged in the inside of the temperature control plate 312, meanwhile, the control switches in the inside of the temperature control plate 312 are respectively positioned at the two sides of the top of the touch rod 314, the top of the temperature control plate 312 is fixedly connected with the gear 315, the inside of the gear 315 is spliced with the driving wheel 316, the outside of the driving wheel 316 is hinged with the driving claw 317, the inner bottom of the sealing cavity 2 is spliced with the carrying mechanism 4, the carrying mechanism 4 comprises a rotary disc 41, the carrying groove is opened in the inside of the rotary disc 41, and the outside of every group carries thing groove all corresponds and has locating piece 46, the position of locating piece 46 is the echelonment simultaneously, carousel 41 fixed connection is in the interior bottom of storage box 1, the bottom welding of carousel 41 has straw 42, straw 42 is connected with spacing bag 411 through the trachea, the bottom of straw 42 articulates there is pneumatic valve 43, the top of pneumatic valve 43 articulates there is connecting rod 44, the top of connecting rod 44 articulates there is sill bar 45, the outside welding of carousel 41 has locating piece 46, the inside grafting of carousel 41 has drive shaft 47, the outside of drive shaft 47 articulates there is driving claw 48, the inside fixedly connected with clamping wheel 49 of carousel 41, the positive meshing of clamping wheel 49 has bevel gear 410, the inside fixedly connected with spacing bag 411 of bevel gear 410, the inner wall sliding connection of bevel gear 410 has fixture block 412, the inside joint of bevel gear 410 has nut 413, the inside joint of nut 413, the inside threaded connection of nut 414 is branch 414 sliding connection is in the inside of carousel 41, and the branch 414 is close to one side fixedly connected with the gyro wheel in the center of carrying thing groove, the left side sliding connection of storage box 1 has magnetic path 5, the left sliding connection of magnetic path 5 has regulation pole 6, the right side sliding connection of regulation pole 6 has, the right side welding of regulation pole 2 has the inner bottom 7 of the air pipe 7, sealing connection 7 has inner bottom 7 sliding connection 7, connecting pipe 7 is connected with connecting pipe 7 through the connecting pipe 7.
A targeted health management method for determining a control target by using gene detection comprises the following steps:
s1, extracting cells or blood of a subject by using a sampler, storing a sample in a reagent bottle, and marking the reagent bottle at the same time;
s2, inserting the reagent bottle into the bracket 32, and keeping the bracket 32 airtight by the swing door 33;
s3, simultaneously starting a heater or a cooler by the temperature control plate 312 through the temperature difference between the internal temperature of the bracket 32 and the internal temperature of the sealed cavity 2;
s4, opening the temperature control plate 312, and inserting the reagent bottles into the carrying grooves in the turntable 41 to finish the storage of the reagent bottles;
s5, after storage is completed, the storage box is taken to a detection chamber for gene detection;
s6, moving the adjusting rod 6 and the magnetic block 5, and then selecting a sample to be extracted through the magnetic block 5 and the positioning block 46;
s7, starting a motor, enabling the bracket 32 to descend through the screw rod 38, and fixing the sampling reagent bottle through the bracket 32 through the clamping rod 310;
s8, taking out the sampling reagent bottles by the bracket 32 through the screw 38, closing the temperature control plate 312, keeping the storage box 1 airtight, and taking out the reagent bottles;
s9, after the reagent bottle is taken out, adding a detection reagent into the bottle, placing the reagent bottle under a gene chip, carrying out gene detection, and recording a detection result;
s10, detecting a plurality of samples according to the steps S6-S9, and completing data analysis.
When in use, a reagent bottle is inserted into the bracket 32, the reagent bottle drives the swinging door 33 to swing downwards, meanwhile, the reagent bottle pushes the clamping rod 310 to slide towards the outer side of the bracket 32, the clamping rod 310 descends under the action of a spring to fix the reagent bottle, the clamping rod 310 enables the air pressure in the air bag 311 to be increased, the air bag 311 reduces the air pressure in the limiting bag 411 through the connecting pipe 7 and the suction pipe 42, at the moment, the clamping wheel 49 rotates to drive the bevel gear 410 to rotate, the bevel gear 410 drives the nut 413 to rotate through the clamping block 412, the nut 413 drives the supporting rod 414 to move, the supporting rod 414 drives the roller to move, when the supporting rod 414 moves to a certain position, the supporting rod 414 stops moving under the action of the spring, the nut 413 limits the nut 413 to rotate, the nut 413 pushes the clamping block 412 to slide, the clamping block 412 presses the limiting bag 411, the smaller the radius of the reagent bottle is, the larger the air pressure in the limiting bag 411 is, the longer the moving distance of the supporting rod 414 is, the storage radius of the carrying groove is smaller, the reagent bottle can be just stored in the carrying groove without shaking, at the moment, the swing door 33 swings back under the action of the spring to close the bracket 32, the bracket 32 seals the temperature control tube 31, when the temperature inside the temperature control tube 31 is lower than the temperature inside the sealing cavity 2, the thrust of the air pressure plate 313 at the bottom of the temperature control plate 312 is larger than the thrust of the air pressure plate 313 at the top, the air pressure plate 313 at the bottom pushes the feeler lever 314 to swing, the feeler lever 314 enables the left control switch to be electrified, the left control switch enables the heater to be started, the heater enables the temperature inside the temperature control tube 31 to rise, when the temperature rises to be the same as the temperature inside the sealing cavity 2, the feeler lever 314 is kept horizontal under the action of the air pressure plate 313, the control switch is powered off, at the moment, the driving wheel 316 is electrified to rotate to drive the driving claw 317 to rotate, the driving claw 317 drives the gear 315 to rotate, the gear 315 drives the temperature control plate 312 to slide rightwards under the action of the tooth groove, the temperature control plate 312 enables the temperature control tube 31 to be communicated with the sealing cavity 2, when the temperature control plate 312 moves to the rightmost side, the driving wheel 316 drives the driving pawl 317 to swing, the driving pawl 317 enables the temperature control plate 312 not to reset, meanwhile, the screw 38 rotates positively under the action of the motor, the rotating wheel 34 does not rotate under the action of the pusher dog 35, the screw 38 rotates positively to drive the rotating wheel 34 to descend, the rotating wheel 34 drives the bracket 32 to descend, the bracket 32 descends to drive the reagent bottle to descend, the reagent bottle is inserted in the carrying groove, the reagent bottle drives the bottom rod 45 to descend, the bottom rod 45 drives the connecting rod 44 to descend, the connecting rod 44 drives the air valve 43 to close, the air valve 43 enables the air pressure in the limiting bag 411 to be kept stable, the reagent bottle storage is not affected, the screw 38 rotates reversely at this moment, the screw 38 rotates reversely to drive the rotating wheel 34 to rotate positively, the rotating wheel 34 drives the pusher dog 35 to rotate through the driving belt, the rotating shaft 39 drives the clamping rod 310 to be far away from the reagent bottle through the winding rope, when the rod clamping rod 310 moves to the inner wall of the bracket 32, the rotating wheel 34 stops rotating under the action of the clamping rod 310, the screw rod 38 drives the rotating wheel 34 to rise, the rotating wheel 34 drives the bracket 32 to rise, reagent bottles are stored, the equipment is powered off, the temperature control plate 312 resets under the action of the spring, the temperature control plate 312 enables the temperature control tube 31 not to be communicated with the sealing cavity 2, the next use is not affected, when the reagent bottles need to be taken out, the adjusting rod 6 is pulled to slide leftwards, the adjusting rod 6 drives the clamping rod to be far away from the clamping groove, at the moment, the adjusting rod 6 is moved, the adjusting rod 6 drives the magnetic block 5 to move, when the magnetic block 5 moves to a desired position, the adjusting rod 6 is released, the adjusting rod 6 drives the clamping rod to be clamped in the clamping groove under the action of the spring, meanwhile, the driving shaft 47 drives the driving claw 48 to rotate, the driving claw 48 drives the rotating disc 41 to rotate, the rotating disc 41 drives the positioning block 46 to rotate, and when the positioning block 46 rotates to the magnetic block 5, the magnetic block 5 limits the rotation of the rotary table 41, at the moment, the driving shaft 47 drives the driving claw 48 to swing, so that a desired reagent bottle can be taken out, at the moment, the screw 38 positively rotates to drive the support 32 to descend, the support 32 descends to drive the clamping rod 310 to be sleeved on the outer side of the reagent bottle, then the screw 38 reversely rotates, meanwhile, the electromagnet 36 is electrified through a switch, the electromagnet 36 drives the stop dog 37 to be close to the pusher dog 35, the stop dog 37 limits the pusher dog 35 to swing, at the moment, the screw 38 reversely rotates to directly drive the rotary wheel 34 to ascend, the rotary wheel 34 drives the support 32 to ascend, the support 32 drives the reagent bottle to ascend, when the support 32 ascends to the top, the equipment is powered off, the temperature control plate 312 is reset, and at the moment, the reagent bottle is taken out.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (2)
1. The utility model provides a utilize gene detection to confirm healthy management device of targeting of prevention and cure target, includes storage box (1), its characterized in that: the utility model provides a storage box, including storage box (1), internally mounted has year thing mechanism (4), carry thing mechanism (4) including carousel (41), carousel (41) fixed connection is in the interior bottom of storage box (1), the bottom welding of carousel (41) has straw (42), the bottom of straw (42) articulates there is pneumatic valve (43), the top of pneumatic valve (43) articulates there is connecting rod (44), the top of connecting rod (44) articulates there is sill bar (45), the outside welding of carousel (41) has locating piece (46), peg graft in the inside of carousel (41) has drive shaft (47), the outside of drive shaft (47) articulates there is driving pawl (48), the inside fixedly connected with tight pulley (49) of carousel (41), the front meshing of tight pulley (49) has bevel gear (410), the inside fixedly connected with spacing bag (411) of bevel gear (410), the inner wall sliding connection of bevel gear (410) has fixture block (412), the inside joint of bevel gear (410) has nut (413), inside connection has screw thread (414) of branch (414). The storage box is characterized by further comprising a sealing cavity (2), wherein the sealing cavity (2) is formed in the storage box (1), an access mechanism (3) is inserted into the top of the sealing cavity (2), a carrying mechanism (4) is inserted into the inner bottom of the sealing cavity (2), a magnetic block (5) is connected to the left side of the storage box (1) in a sliding manner, an adjusting rod (6) is connected to the left side of the magnetic block (5) in a sliding manner, a connecting pipe (7) is connected to the inner bottom of the sealing cavity (2) in a sliding manner, and a push rod (8) is connected to the inner bottom of the connecting pipe (7) in a sliding manner; a clamping rod is welded on the right side of the adjusting rod (6); the access mechanism (3) comprises a temperature control tube (31), the temperature control tube (31) is inserted at the top of the sealing cavity (2), a bracket (32) is connected to the inner wall of the temperature control tube (31) in a sliding manner, a swinging door (33) is hinged to the top of the bracket (32), a rotating wheel (34) is inserted at the bottom of the bracket (32), a pusher dog (35) is hinged to the inner wall of the bracket (32), an electromagnet (36) is fixedly connected to the inner part of the bracket (32), a stop block (37) is connected to the inner part of the electromagnet (36) in a sliding manner, a screw (38) is connected to the inner thread of the rotating wheel (34), a scroll (39) is inserted to the inner wall of the bracket (32), a clamping rod (310) is connected to the inner wall of the bracket (32) in a sliding manner, an air bag (311) is fixedly connected to one side of the clamping rod (310) away from the scroll (39), a temperature control plate (312) is connected to the bottom of the temperature control tube (31) in a sliding manner, an air pressure plate (313) is connected to the inner part of the temperature control plate (312) in a sliding manner, an air pressure plate (315) is connected to the inner side of the temperature control plate (312) in a sliding manner, a screw (315) is connected to the inner side of the air pressure control plate (315), a driving claw (317) is hinged to the outer side of the driving wheel (316); the middle position of the feeler lever (314) is hinged in the temperature control plate (312), and meanwhile, control switches in the temperature control plate (312) are respectively positioned at two sides of the top of the feeler lever (314); the inner part of the turntable (41) is provided with object carrying grooves, the outer sides of each group of object carrying grooves are respectively provided with a positioning block (46), and meanwhile, the positioning blocks (46) are in a step shape.
2. The targeted health management device for determining control targets by gene detection according to claim 1, wherein: the support rod (414) is connected inside the turntable (41) in a sliding mode, and a roller is fixedly connected to one side, close to the center of the carrying groove, of the support rod (414).
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| CN101389956B (en) * | 2005-12-21 | 2013-01-02 | 三星电子株式会社 | Bio memory disc and bio memory disc drive apparatus, and assay method using the same |
| EP2743614B1 (en) * | 2012-12-12 | 2019-10-02 | Liconic Ag | Storage cartridge for laboratory objects |
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| US5320808A (en) * | 1988-08-02 | 1994-06-14 | Abbott Laboratories | Reaction cartridge and carousel for biological sample analyzer |
| WO2008123882A1 (en) * | 2007-04-06 | 2008-10-16 | Richard Obiso | Sample preparation system for processing of clinical specimens |
| CN211487796U (en) * | 2019-12-25 | 2020-09-15 | 成都市新都区人民医院 | Anti-pollution storage device for clinical laboratory |
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