CN110596408A - Full-automatic dry immunoassay equipment - Google Patents
Full-automatic dry immunoassay equipment Download PDFInfo
- Publication number
- CN110596408A CN110596408A CN201910893591.2A CN201910893591A CN110596408A CN 110596408 A CN110596408 A CN 110596408A CN 201910893591 A CN201910893591 A CN 201910893591A CN 110596408 A CN110596408 A CN 110596408A
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- fixedly connected
- block
- liquid taking
- immunoassay analyzer
- gear
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- 238000003018 immunoassay Methods 0.000 title claims abstract description 45
- 230000007246 mechanism Effects 0.000 claims abstract description 98
- 239000007788 liquid Substances 0.000 claims abstract description 60
- 238000012360 testing method Methods 0.000 claims abstract description 52
- 238000001514 detection method Methods 0.000 claims abstract description 37
- 238000011084 recovery Methods 0.000 claims description 12
- 238000000605 extraction Methods 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 12
- 230000008569 process Effects 0.000 abstract description 12
- 239000002699 waste material Substances 0.000 abstract description 5
- 239000008280 blood Substances 0.000 description 21
- 210000004369 blood Anatomy 0.000 description 21
- 230000008878 coupling Effects 0.000 description 13
- 238000010168 coupling process Methods 0.000 description 13
- 238000005859 coupling reaction Methods 0.000 description 13
- 210000000078 claw Anatomy 0.000 description 7
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 5
- 229960002897 heparin Drugs 0.000 description 5
- 229920000669 heparin Polymers 0.000 description 5
- 238000010241 blood sampling Methods 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 208000027205 Congenital disease Diseases 0.000 description 1
- 101100293261 Mus musculus Naa15 gene Proteins 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000002337 anti-port Effects 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000004020 luminiscence type Methods 0.000 description 1
- 230000007102 metabolic function Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
Abstract
The invention discloses a full-automatic dry immunoassay device, which comprises: a base; the detection mechanism is fixedly connected to the base; the feeding mechanism is arranged at a distance from the detection mechanism; and the liquid taking mechanism is positioned right above the side of the feeding mechanism, and the liquid taking mechanism is used for moving back and forth between the detection mechanism and the feeding mechanism, wherein the detection mechanism is provided with a turntable, an enclosing baffle plate extends upwards along one circle of the periphery of the turntable, and at least two peak platforms are arranged on the enclosing baffle plate at intervals. According to the invention, the feeding mechanism and the detection mechanism are set to be rotary and provided with a plurality of accommodating tanks, so that the number of disposable test samples is increased, the work efficiency of the test is improved, the whole processes of feeding, liquid taking, detection and waste treatment are fully automatic, the work efficiency is further improved, and the feeding mechanism can be used for accommodating test tubes of all specifications, so that the applicability of the device is higher.
Description
Technical Field
The invention relates to the field of immunoassay analyzer equipment, in particular to full-automatic dry immunoassay equipment.
Background
The full-automatic chemiluminescence immunoassay instrument is an instrument capable of carrying out immunological quantitative analysis on a body fluid sample of a patient, and can be used for detecting anemia, cardiovascular diseases, congenital diseases, sex hormones, infectious diseases, metabolic functions, tumor markers, thyroid and the like and monitoring treatment medicines.
At present, when the immune item detection is carried out in the inspection departments such as outpatient service, emergency treatment and the like, for a single device, after a nurse takes blood, blood taking tubes are intensively placed into a table centrifuge. Generally, a medical worker always waits for at least one small batch of samples, then manually puts the samples into a centrifuge for centrifugation, then takes the samples out of the centrifuge, removes a test tube cap, and puts the samples into a full-automatic luminescence analyzer for testing, wherein various implemented steps are manual operations.
However, the existing immunoassay analyzer has certain problems, one of which is that a plurality of parts which involve manual operation in a whole set of detection process are provided, so that the detection work is inefficient in the daily detection process. Secondly, adopt the structure of carousel formula to the process that the chemical examination detected and the material loading, including many holding tanks, can improve disposable detection and analysis's process and efficiency greatly, but most analyzer's equipment can detect the sample quantity of analysis few, and it is long to consume time. Thirdly, the general immunoassay analyzer is only suitable for detecting blood sampling tubes with the conventional size,
in view of the above, there is a need to develop a fully automatic dry immunoassay device to solve the above problems.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide a full-automatic dry immunoassay device, which improves the number of disposable test samples and improves the work efficiency of test by arranging a feeding mechanism and a detection mechanism in a rotary mode and arranging a plurality of accommodating grooves, the whole processes of feeding, liquid taking, detection and waste treatment are fully automatic processes, the work efficiency is further improved, test tubes of all specifications can be placed in the feeding mechanism, the applicability of the device is higher, and in order to realize the aim and other advantages, the full-automatic dry immunoassay device comprises:
a base;
the detection mechanism is fixedly connected to the base;
the feeding mechanism is arranged at a distance from the detection mechanism; and
a liquid taking mechanism which is positioned right above the side of the feeding mechanism and moves back and forth between the detection mechanism and the feeding mechanism,
the detection mechanism is provided with a rotary table, an enclosing baffle plate extends upwards along the periphery of the rotary table, and at least two peak platforms are arranged on the enclosing baffle plate at intervals.
Preferably, the detection mechanism further includes:
a fixed cylinder;
the first-stage rotary drum is sleeved on the periphery of the cylinder; and
a second-stage rotating drum which is sleeved on the periphery of the first-stage rotating drum,
the end surfaces of the cylinder, the first-stage rotating drum and the second-stage rotating drum are stepped and sequentially pushed downwards, the upper end surface of the second-stage rotating drum is fixedly connected with a rotating disc, and the upper end surface of the first-stage rotating drum is fixedly connected with a transverse pushing mechanism.
Preferably, the transverse pushing mechanism comprises a gear shaft motor, a fixed disc and a push rod, wherein a through groove is formed in the middle of the push rod along the length direction, the width of the through groove is slightly larger than the diameter of a gear shaft of the gear shaft motor, two side faces of the through groove are respectively and fixedly connected with a tooth-shaped strip and an I-shaped track strip, a sliding rail block is arranged on the side face of the through groove and is matched with the I-shaped track strip, a pressing block is fixedly connected with the sliding rail block.
Preferably, the feeding mechanism comprises a rotary table, a support frame and a recovery mechanism, and the rotary table is provided with a feeding station, a decapping station, a liquid pumping station and a recovery station which are sequentially arranged along the rotation direction of the rotary table.
Preferably, at least two test tube holding tanks of arranging along its circumference are seted up to the periphery of carousel, there is the adapter in the test tube holding tank, the holding tank is put to the test tube and is held the chamber around forming one by the lateral wall, it has vertical locating piece of placing to hold the rigid coupling on the intracavity wall, the locating hole has been seted up on the locating piece, the bottom device that holds the chamber has the fixed block, the fixed orifices has been seted up in the downward run-through of fixed block upper surface.
Preferably, the support frame is fixedly connected with the recovery mechanism, a gun head tray is fixedly connected to the support frame, a gun head tray support frame is fixedly connected to the gun head tray, the gun head tray is L-shaped and is divided into a flat component and a vertical component, the flat component is fixedly connected to the support frame, a square hole is formed in the middle of the flat component, an automatic missile device is arranged below the square hole, the automatic missile device is fixedly connected to the support frame, and the drawer adjusting sheet is fixedly connected to the inner wall of the vertical component.
Preferably, the liquid taking mechanism comprises a liquid taking pipe structure and a driving structure, and the driving structure drives the liquid taking pipe structure to do linear motion along the horizontal direction.
Preferably, the liquid taking pipe structure is provided with a liquid taking pipe part, the liquid taking pipe part is fixedly connected with a liquid taking pipe fixing block, the liquid taking pipe fixing block is fixedly connected with a bearing fixing block, the bearing fixing block is fixedly connected with a vertical sliding block, and the vertical sliding block is fixedly connected with a vertical bar-shaped connecting block.
Preferably, the bottom rigid coupling of bar connecting block has the loading base that the level was placed, it has gear motor to load base left end face rigid coupling, gear motor runs through load the base downwardly extending, it has the rotation to load base right-hand member face rigid coupling, the one end of axis of rotation is rotating gear, rotating gear upwards runs through bearing solid joint piece.
Preferably, the drive structure is equipped with transverse connection board, transverse connection board one end rigid coupling has first gear motor, the transverse connection board other end is equipped with the gear shaft, with first gear motor establish relatively in there is transverse solid joint piece on the transverse connection board, transverse connection board's upper and lower both sides side is equipped with first slip track and second slip track, first slip track with be equipped with relative first slider and second slider on the second slip track respectively, transverse solid joint piece is fixed in first slider with on the second slider.
Compared with the prior art, the invention has the beneficial effects that: establish to the rotation type and be equipped with a plurality of holding tanks through establishing feed mechanism and detection mechanism, improve the quantity of disposable inspection sample, improve the work efficiency of inspection, holistic material loading, get liquid, detect and waste disposal's process is full automatic process, and the efficiency of further improvement work, feed mechanism equipment can place the test tube of whole specifications moreover, and the suitability of equipment is higher.
Drawings
FIG. 1 is a three-dimensional view of the external appearance structure of an immunoassay analyzer device according to the present invention;
FIG. 2 is a three-dimensional schematic view of the internal structure of an immunoassay analyzer device according to the present invention;
FIG. 3 is a three-dimensional schematic view of a turnaround feed mechanism of an immunoassay analyzer apparatus according to the present invention;
fig. 4 is a three-dimensional exploded view of a rotating gripper assembly of the epicyclic feed mechanism of the immunoassay analyzer apparatus according to the present invention;
FIG. 5 is a three-dimensional exploded schematic view of a holding member driving structure of an immunoassay analyzer apparatus according to the present invention;
fig. 6 is a three-dimensional schematic view of a support mechanism of the rotary gripper unit of the immunoassay analyzer apparatus according to the present invention.
FIG. 7 is a three-dimensional exploded schematic view of the turnaround feed mechanism of the immunoassay analyzer apparatus according to the present invention;
FIG. 8 is a three-dimensional schematic view of the carousel of the epicyclic feeder of the immunoassay analyzer apparatus according to the present invention;
FIG. 9 is a top plan view of the carousel of the epicyclic feeder of the immunoassay analyzer apparatus according to the present invention;
FIG. 10 is a three-dimensional schematic view of a support frame of an epicyclic feeder of an immunoassay analyzer apparatus according to the present invention;
FIG. 11 is a three-dimensional schematic view of a detection disc for an immunoassay test paper sheet of the immunoassay analyzer apparatus according to the present invention;
FIG. 12 is a schematic three-dimensional exploded view of a detection disc for an immunoassay test paper sheet of an immunoassay analyzer apparatus according to the present invention;
FIG. 13 is a three-dimensional schematic view of a lateral pushing mechanism of a test disc for an immunoassay test paper sheet of the immunoassay analyzer apparatus according to the present invention;
FIG. 14 is a three-dimensional schematic view of a turntable of a detection disk for an immunoassay test paper sheet of the immunoassay analyzer apparatus according to the present invention;
FIG. 15 is a left side view of a liquid take-off structure and a turnaround feeder of an immunoassay analyzer apparatus according to the present invention;
FIG. 16 is a schematic three-dimensional view of a liquid taking mechanism of an immunoassay analyzer apparatus according to the present invention;
FIG. 17 is a three-dimensional schematic view of a fluid extraction member of an immunoassay analyzer apparatus according to the present invention;
FIG. 18 is a three-dimensional schematic view of the exterior of the pipetting drive structure of an immunoassay analyzer device according to the present invention;
fig. 19 is a three-dimensional schematic view of the interior of the liquid-extracting drive structure of the immunoassay analyzer apparatus according to the present invention.
Detailed Description
The foregoing and other objects, features, aspects and advantages of the present invention will become more apparent from the following detailed description of the present invention when taken in conjunction with the accompanying drawings, which will enable those skilled in the art to practice the present invention with reference to the accompanying specification. In the drawings, the shape and size may be exaggerated for clarity, and the same reference numerals will be used throughout the drawings to designate the same or similar components. In the following description, terms such as center, thickness, height, length, front, back, rear, left, right, top, bottom, upper, lower, and the like are used based on the orientation or positional relationship shown in the drawings. In particular, "height" corresponds to the dimension from top to bottom, "width" corresponds to the dimension from left to right, and "depth" corresponds to the dimension from front to back. These relative terms are for convenience of description and are not generally intended to require a particular orientation. Terms concerning attachments, coupling and the like (e.g., "connected" and "attached") refer to a relationship wherein structures are secured or attached, either directly or indirectly, to one another through intervening structures, as well as both movable or rigid attachments or relationships, unless expressly described otherwise.
Referring to fig. 1-19, an immunoassay analyzer device includes:
a base 7;
the detection mechanism 4 is fixedly connected to the base 7;
the feeding mechanism 1 is arranged at a distance from the detection mechanism 4; and
a liquid taking mechanism 6 which is positioned right above the side of the feeding mechanism 1, and the liquid taking mechanism 6 moves back and forth between the detection mechanism 4 and the feeding mechanism 1,
referring to fig. 14, the detecting mechanism 4 is provided with a rotating disc 44, a fence extends upwards along the periphery of the rotating disc 44, at least two peak platforms 441 are arranged on the enclosure baffle at intervals, a test paper sheet is arranged between every two adjacent peak platforms 41, a placing position 412 corresponding to one end of the test paper sheet is arranged on one side of the upper surface of each peak platform 41, a placing position 411 corresponding to the other end of the test paper sheet is arranged on the other side of the upper surface of each peak platform 41, therefore, the test paper sheet can be stably arranged on the rotating disc 44, the rotating disc 44 will not easily fall off during the rotation process, the peak platform 441 is respectively provided with a placing position 412 and a placing position 411 at two sides of the upper end surface according to the size of the two ends of the test paper sheet, two adjacent peak platforms 441 can be well embedded to place test paper sheets, and the embedding tightness is moderate, so that the transverse pushing mechanism 41 can conveniently push the test paper sheets after the test paper sheets are detected.
Referring to fig. 4-6, uncapping mechanism 2 is further provided directly above feeding mechanism 1, uncapping mechanism 2 is divided into a rotating clamp part 21 and a clamping part 22, wherein the rotating clamp part 21 includes the jaw seat 211, the clamping jaw 212, the rotating shaft 215 and the clamping jaw opening and closing device 213, the t-shaped sleeve 216 is sleeved on the periphery of the lower end of the rotating shaft 215, the lower end of the t-shaped sleeve 216 is fixedly connected with the connecting top plate 217, the lower surface of the connecting top plate 217 is fixedly connected with the clamping jaw opening and closing device 213, the clamping jaw opening and closing device 213 is used for controlling the opening and closing of the clamping jaw 212, when the rotating clamp part 21 descends to the top of the blood collection tube, the clamping jaw opening and closing device 213 controls the clamping jaw 212 to open and contain the lid of the blood collection tube, then the clamping jaw 212 performs the combination action to grasp the lid of the blood collection tube, at this time, the jaw 212 descends to the top of the cartridge with the cap, and when the cap is screwed onto the cartridge, the jaw opening and closing device 213 controls the jaw 212 to open again.
Further, the motor bottom plate 58 and the connecting push plate 53 sequentially penetrate through the rotating shaft 215 upward, the first motor 57 is disposed at the left end of the motor bottom plate 58, the first motor 57 is disposed with the motor screw 54, one end of the motor screw 54 penetrates through the motor bottom plate 58 and extends downward, the other end of the motor screw is fixed to the lower surface of the connecting push plate 53, when the clamping member 4 clamps and fixes the blood collection tube, the rotating clamping member 21 needs to descend to the cap of the blood collection tube to uncap the blood collection tube, at this time, the first motor 57 rotates to drive the motor screw 5 to rotate, the motor screw 5 drives the connecting push plate 53 to do ascending and descending linear motion, the rotating shaft 215 rotates the rotating shaft 215 through the rotating shaft 2151, and the rotating shaft 215 finally enables the clamping jaws 212 to spirally ascend when clamping the cap, so that the jaws 212 can be screwed off the cap.
Further, the clamping component 4 is provided with the second motor 221, the second motor 221 is provided with the motor base 222, a rotating shaft of the second motor 221 penetrates through the motor base 222, the driving gear 223 is sleeved on the upper end of the rotating shaft, and the driving gear 223 is engaged with the first driven gear 225 and the second driven gear 224 engaged with the first driven gear 225.
Further, the upper ends of the first driven gear 225 and the second driven gear 224 are respectively rotatably connected with the first annular seat 228 and the second annular seat 2210, the finger clamping seat 2282 is fixedly connected to the outer circumference of the first annular seat 228, the finger clamping seat 2282 is fixedly connected to the finger clamping seat 2283, the finger clamping head 2283 is sleeved with the silica gel finger pad 227, when the blood collection tube reaches the uncapping station, the clamping member 4 clamps and fixes the blood collection tube, when the second motor 221 rotates, the first driven gear 225 and the second driven gear 224 move in opposite directions, so that the first annular seat 228 and the finger clamping head on the second annular seat 2210 are combined to clamp the blood collection tube, when the rotary clamping member 21 uncapping the blood collection tube, when the detection is completed, the second motor 221 operates in reverse direction, so that the clamping jaws are separated to release the clamping of the cartridge.
Further, at least two of the finger holders 22101 are fixedly connected to the outer circumference of the second annular seat 2210, and the clamping jaw 22103 and the guiding jaw 22102 are respectively fixedly connected to the finger holders 22101.
Further, still the rigid coupling has on the first annular seat 228 periphery spacing clip indicates seat 2281, be close to spacing clip indicates seat 2281 be provided with on the motor cabinet 222 stopper 229, just clip indicates seat 2282 with be fixed in between the spacing clip indicates seat 2281 first annular seat 228 is equipped with press from both sides tight barn door.
Further, the detection mechanism 4 further includes:
a fixed cylinder 47;
a first-stage drum 48 fitted around the outer periphery of the cylinder 47; and
a second-stage drum 46, which is sleeved on the periphery of the first-stage drum 48,
the end surfaces of the cylinder 47, the first-stage rotating drum 48 and the second-stage rotating drum 46 are stepped and sequentially pushed downwards, the upper end surface of the second-stage rotating drum 46 is fixedly connected with the rotating disc 44, and the upper end surface of the first-stage rotating drum 48 is fixedly connected with the transverse pushing mechanism 41.
Referring to fig. 13, the lateral pushing mechanism 41 includes a gear shaft motor 411, a fixed plate 417, and a push rod 414, a through groove is formed in the middle of the push rod 144 along the length direction, the width of the through groove is slightly larger than the gear shaft diameter of the gear shaft motor 411, a tooth-shaped strip 415 and an i-shaped track strip 416 are respectively fixedly connected to two side edges of the through groove, a sliding rail block 413 is arranged to fit with the i-shaped track strip 416, a pressing block 412 is fixedly connected to the sliding rail block 413, the pressing block 412 is fixed on the fixed plate 417, the lateral pushing mechanism 41 includes a gear shaft motor 411, a fixed plate 417, and a push rod 414, a through groove is formed in the middle of the push rod 414 along the length direction, the width of the through groove is slightly larger than the gear shaft diameter of the gear shaft motor 411, the upper surface of the push rod 414 is far higher than the fixed plate 417, the push rod 414, so that the test paper sheet can be accurately and effectively pushed in the pushing process.
Furthermore, a test paper sheet recovery box is arranged beside the detection mechanism 4 and in the transverse pushing direction of the transverse pushing mechanism 41, and after the test paper sheet is detected, the transverse pushing mechanism 41 pushes the test paper sheet to the test paper sheet recovery box.
Tooth-shaped strips 145 and I-shaped track strips 146 are fixedly connected to two side edges of the through groove respectively, a sliding rail block 413 is arranged corresponding to the I-shaped track strips 416, a pressing block 412 is fixedly connected to the sliding rail block 413, and the pressing block 412 is fixed to a fixed disc 417.
Further, feed mechanism 1 is including carousel 11, support frame 12 and recovery mechanism 15, be equipped with the material loading station, uncapping station, drawing liquid station and the recovery station that arrange in proper order along its direction of rotation on carousel 11.
Referring to fig. 8-9, the outer circumference of the rotary disk 11 is provided with at least two test tube receiving grooves arranged along the circumferential direction thereof, the test tube accommodating groove is provided with an adapter 3, the test tube accommodating groove is surrounded by a side wall 112 to form an accommodating cavity, a vertically arranged positioning block 111 is fixedly connected to the inner wall of the accommodating cavity, a positioning hole 1111 is formed in the positioning block 111, the bottom of the containing cavity is provided with a fixed block 113, the upper surface of the fixed block 113 is downwards penetrated with a fixed hole 1131, the adapter is arranged in the test tube accommodating groove, the test tube accommodating groove is surrounded by the side wall to form an accommodating cavity, the inner wall of the accommodating cavity is fixedly connected with the vertically arranged positioning block, the positioning block is provided with the positioning hole, the bottom device that holds the chamber has the fixed block, the fixed block upper surface has run through downwards and has seted up the fixed orifices. This the test tube of carousel is put and is received the position and can place ordinary blood sampling test tube commonly used, also can be equipped with the test tube the adapter places unconventional blood sampling test tube, moreover to unconventional test tube the adapter can make its fixed placing in the carousel, locating hole 1111 can fix the orientation of placing of adapter, can prevent that the adapter is placed conversely.
Further, the support frame 12 is fixedly connected with the recovery mechanism 15, a gun head tray 151 is fixedly connected to the support frame, a gun head tray support frame 152 is fixedly connected to the gun head tray 151, the gun head tray 151 is L-shaped and is divided into a flat component and a vertical component, the flat component is fixedly connected to the support frame, a square hole is formed in the middle of the flat component, an automatic missile device 155 is arranged below the square hole, the automatic missile device 155 is fixedly connected to the support frame, and a drawer adjusting sheet 153 is fixedly connected to the inner wall of the vertical component.
Referring to fig. 16, the liquid taking mechanism 6 includes a liquid taking tube structure 61 and a driving structure 62, the driving structure 62 drives the liquid taking tube structure 61 to move linearly along a horizontal direction, mainly, the liquid taking tube structure 61 is fixed on the driving structure 62, the driving structure 62 drives the liquid taking tube structure 61 to move transversely through a motor, so that the liquid taking tube structure 61 moves from a starting station to above the revolving and feeding mechanism 1, and at this time, the liquid taking tube structure 61 moves downward to take liquid.
Further, liquid taking pipe structure 61 is equipped with liquid taking pipe part 611, with liquid taking pipe part 611 rigid coupling has liquid taking pipe fixed block 618, liquid taking pipe fixed block 618 rigid coupling has bearing rigid coupling block 619, the bearing rigid coupling block 619 rigid coupling has vertical slider 6110, vertical slider 6110 rigid coupling has vertical bar connecting block 614.
Referring to fig. 17, a horizontally disposed loading base 613 is fixedly connected to a bottom end of the bar-shaped connecting block 614, a gear motor 612 is fixedly connected to a left end surface of the loading base 613, the gear motor 612 can rotate forward or backward, the gear motor 612 penetrates through the loading base 613 and extends downward, a rotating shaft 617 is fixedly connected to a right end surface of the loading base 613, one end of the rotating shaft 617 is a rotating gear 615, the rotating gear 615 penetrates through the bearing fixing block 619 upward, the rotating gear 615 is driven to rotate when the gear motor 612 rotates, the rotating gear 615 drives the bearing fixing block 619 to move downward or upward, and the liquid taking pipe member 611 is fixedly connected to the bearing fixing block 619, so that the liquid taking pipe member 611 follows the upward or downward movement of the bearing fixing block 619.
Referring to fig. 19, the driving structure 62 is provided with a transverse connecting plate 622, one end of the transverse connecting plate 622 is fixedly connected with a first gear motor 621, the other end of the transverse connecting plate 622 is provided with a gear shaft 626, a transverse fixing block 624 is arranged on the transverse connecting plate 622 opposite to the first gear motor 621, the upper and lower sides of the transverse connecting plate 622 are provided with a first sliding rail 6212 and a second sliding rail 6211, the first sliding rail 6212 and the second sliding rail 6211 are respectively provided with a first sliding block 6210 and a second sliding block 628 which are opposite to each other, the transverse fixing block 624 is fixed on the first sliding block 6210 and the second sliding block 628, the first gear motor 621 is connected with the gear shaft 626 through a belt, and the transverse fixing block 624 is fixedly connected with a belt driving block 629, when the first gear motor rotates, the belt is driven to rotate, because the belt driving block 629 is fastened to the belt, the transverse fastening block 624 moves transversely with the belt, thereby moving the entire liquid taking mechanism transversely.
Furthermore, a first connecting plate 623 and a second connecting plate 627 are respectively arranged on the upper side and the lower side of the transverse connecting plate 622, a third connecting plate is arranged at the upper end of the second connecting plate 627, an X-axis moving chain is fixedly connected to the first connecting plate 623 and the second connecting plate 627, a Y-axis moving chain is fixedly connected with the third connecting plate, a top plate is fixed at the other end of the Y-axis moving chain, two Y-axis slide rails are fixed on the top plate, Y-axis slide blocks are fixedly connected on the Y-axis slide rails, one of the Y-axis sliders is fixedly connected to the transverse connecting plate 622, the other Y-axis slider is fixedly connected to the transverse connecting plate 622 through a middle block, the middle block is fixed on the transverse connecting plate 622, a motor rotating seat is fixedly connected on the middle block, a Y-axis motor is fixedly connected on the motor rotating seat, when the Y-axis motor rotates, the middle block drives the liquid taking mechanism 61 to move along the Y axis.
In the work, the test tube to be detected is manually placed in the rotary table 11, at this time, when the sample loading sensor 16 on the support frame 12 senses that the blood collection tube is placed on the rotary table 11, the driving mechanism 14 starts to drive the rotary table 11 to rotate to the uncapping station, when the uncapping sensor 17 senses that the rotary table 11 rotates to the uncapping station, the driving mechanism 14 stops rotating, the blood collection tube is uncapping, after the uncapping operation is finished, the driving mechanism 14 drives the rotary table 11 to rotate to the next detection station, when the sensor on the liquid taking mechanism senses the test tube, the liquid taking tube part in the liquid taking mechanism moves in the X-axis direction to the upper part of the test tube, at this time, the liquid taking tube part starts to move downwards to take liquid, when the liquid taking mechanism 6 finishes taking liquid, the detected blood collection tube is recovered to the recovery device 15, when the turntable rotates to the uncapping station, at this time, a test tube sensor senses that a blood collection tube reaches the uncapping station, at this time, the clamping claw 22102 is guided to guide the blood collection tube to the uncapping station, when the blood collection tube reaches the uncapping station, the second motor 221 is turned on to drive the driving gear 223 to rotate, so that the first driven gear 225 and the second driven gear 224 rotate, at this time, the clamping claw 2283 with the silica gel finger pad 227 clamps the blood collection tube, at this time, the first motor 57 rotates to drive the motor screw 54 to rotate downwards to drive the slider 52 to slide downwards along the i-shaped slide rail 55, when the slider slides above the blood collection tube, the rotary clamping part 21 opens the claw 212 through the uncapping opening and closing device 213, then the uncapping opening and closing device 213 enables the claw to clamp the cap of the blood collection tube, at this time, the first motor 417 drives the motor screw 414 to spirally rise, drive rotatory clamp is got 21 spiral rises of part 21 and is taking off the heparin tube cap lid of rotation type promptly, avoids adopting the linear to pull hard required strength of taking off the cap and reduces, works as rotatory clamp is got part 21 and is accomplished the action of taking off the cap, second motor 221 antiport, thereby makes centre gripping claw 2283 loosens the heparin tube, turns to the heparin tube both sides, on first driven gear 225 spacing clamp indicates the seat 2281 displacement to stopper 229's position stops centre gripping claw 2283 and the rotation of holding claw 22103, and whole process of taking off the cap ends, and the heparin tube also accomplishes the detection this moment, carousel 11 is in carousel actuating mechanism 14's drive is transferred to the waste tube down retrieve mechanism 15, and the heparin tube that accomplishes the detection this moment is placed in the waste tube retrieve mechanism 15 and retrieve in unison, and whole feed mechanism accomplishes all work steps this moment.
When the liquid taking mechanism 6 obtains an object to be detected, the Y-axis motor starts to rotate at the moment to drive the liquid taking mechanism 6 to move in the Y-axis direction, when the sensor senses that the liquid taking mechanism 6 moves above the test paper sheet, the Y-axis motor stops rotating at the moment, the liquid taking mechanism 6 starts to move downwards to drop the obtained object to be detected onto the test paper sheet, then the test paper sheet moves upwards, the Y-axis motor rotates reversely to drive the liquid taking mechanism 6 to return to the original position, the motor 421 rotates to drive the turntable 44 to rotate at the moment, the test paper sheet to be detected rotates to a detection area to be detected, after the test paper sheet is detected, the motor 421 rotates reversely to drive the test paper sheet to rotate to the position of the transverse pushing mechanism 41, the gear shaft motor 411 rotates at the moment, the gear shaft motor 411 drives the gear rack 415 to move linearly to drive the push rod 414 to move linearly forwards, the push rod 414 moves towards the test paper sheet along the slide rail block 413 to push the test paper sheet out of the peak platform 41, at this time, the limiting piece 418 on the tooth-shaped strip 415 reaches the limiting block 419, the push rod 414 can not move forwards any more, so that the push rod 414 can not easily move to be separated excessively, and after the test paper sheet is pushed out, the limiting piece 418 rotates reversely to drive the push rod 414 to move linearly in a reverse direction to return to the initial position.
While embodiments of the invention have been described above, it is not limited to the applications set forth in the description and the embodiments, which are fully applicable in various fields of endeavor to which the invention pertains, and further modifications may readily be made by those skilled in the art, it being understood that the invention is not limited to the details shown and described herein without departing from the general concept defined by the appended claims and their equivalents.
Claims (10)
1. A fully automatic dry immunoassay device, comprising:
a base (7);
the detection mechanism (4) is fixedly connected to the base (7);
the feeding mechanism (1) is arranged at a distance from the detection mechanism (4); and
the liquid taking mechanism (6) is positioned right above the side of the feeding mechanism (1), and the liquid taking mechanism (6) moves back and forth between the detection mechanism (4) and the feeding mechanism (1),
wherein, detection mechanism (4) are equipped with carousel (44), follow carousel (44) periphery round upwards extends and has enclosed the baffle, enclose the baffle and go up the interval and seted up two at least peak platforms (441).
2. The immunoassay analyzer device of claim 1, wherein the detection mechanism (4) further comprises:
a fixed cylinder (47);
a first-stage drum (48) which is sleeved on the periphery of the cylinder (47); and
a second-stage rotary drum (46) which is sleeved on the periphery of the first-stage rotary drum (48),
the end faces of the cylinder (47), the first-stage rotary drum (48) and the second-stage rotary drum (46) are stepped and sequentially pushed downwards from top to bottom, the upper end face of the second-stage rotary drum (46) is fixedly connected with a rotary disc (44), and the upper end face of the first-stage rotary drum (48) is fixedly connected with a transverse pushing mechanism (41).
3. The immunoassay analyzer apparatus of claim 2, wherein the lateral pushing mechanism (41) comprises a gear shaft motor (411), a fixed plate (417) and a push rod (414), a through groove is formed in the middle of the push rod (144) along the length direction, the width of the through groove is slightly larger than the gear shaft diameter of the gear shaft motor (411), a tooth-shaped strip (415) and an i-shaped track strip (416) are respectively fixedly connected to two side edges of the through groove, a sliding rail block (413) is arranged to be matched with the i-shaped track strip (416), a pressing block (412) is fixedly connected to the sliding rail block (413), and the pressing block (412) is fixed to the fixed plate (417).
4. The immunoassay analyzer apparatus of claim 1, wherein the feeding mechanism (1) comprises a turntable (11), a supporting frame (12) and a recovery mechanism (15), and the turntable (11) is provided with a feeding station, a decapping station, a liquid extraction station and a recovery station which are sequentially arranged along a rotation direction of the turntable.
5. The immunoassay analyzer device of claim 4, wherein the periphery of the rotating disk (11) is provided with at least two test tube accommodating grooves arranged along the circumferential direction thereof, the test tube accommodating grooves are provided with adapters (3), the test tube accommodating grooves are surrounded by side walls (112) to form an accommodating cavity, the inner wall of the accommodating cavity is fixedly connected with a vertically arranged positioning block (111), the positioning block (111) is provided with a positioning hole (1111), the bottom device of the accommodating cavity is provided with a fixing block (113), and the upper surface of the fixing block (113) is provided with a fixing hole (1131) in a downward penetrating manner.
6. The immunoassay analyzer device of claim 4, wherein the recovery mechanism (15) is fixedly connected to the support frame (12), a tip tray (151) is fixedly connected to the support frame, a tip tray support frame (152) is fixedly connected to the tip tray (151), the tip tray (151) is L-shaped and is divided into a horizontal component and a vertical component, the horizontal component is fixedly connected to the support frame, a square hole is formed in the middle of the horizontal component, an automatic projectile launcher (155) is arranged below the square hole, the automatic projectile launcher (155) is fixedly connected to the support frame, and the drawer adjustment sheet (153) is fixedly connected to the inner wall of the vertical component.
7. The immunoassay analyzer apparatus of claim 1, wherein the liquid extracting mechanism (6) comprises a liquid extracting tube structure (61) and a driving structure (62), wherein the driving structure (62) drives the liquid extracting tube structure (61) to move linearly along a horizontal direction.
8. The immunoassay analyzer apparatus of claim 7, wherein the liquid taking tube structure (61) is provided with a liquid taking tube part (611), a liquid taking tube fixing block (618) is fixedly connected with the liquid taking tube part (611), the liquid taking tube fixing block (618) is fixedly connected with a bearing fixing block (619), the bearing fixing block (619) is fixedly connected with a vertical slide block (6110), and the vertical slide block (6110) is fixedly connected with a vertical strip-shaped connecting block (614).
9. The immunoassay analyzer apparatus of claim 8, wherein a horizontally disposed loading base (613) is fixed to a bottom end of the strip-shaped connecting block (614), a gear motor (612) is fixed to a left end face of the loading base (613), the gear motor (612) extends downward through the loading base (613), a rotating shaft (617) is fixed to a right end face of the loading base (613), a rotating gear (615) is provided at one end of the rotating shaft (617), and the rotating gear (615) extends upward through the bearing fixing block (619).
10. The immunoassay analyzer apparatus of claim 7, wherein the driving structure (62) is provided with a transverse connecting plate (622), one end of the transverse connecting plate (622) is fixedly connected with a first gear motor (621), the other end of the transverse connecting plate (622) is provided with a gear shaft (626), a transverse fixing block (624) is arranged on the transverse connecting plate (622) opposite to the first gear motor (621), the upper side and the lower side of the transverse connecting plate (622) are provided with a first sliding track (6212) and a second sliding track (6211), the first sliding track (6212) and the second sliding track (6211) are respectively provided with a first sliding block (6210) and a second sliding block (628) which are opposite, and the transverse fixing block (624) is fixed on the first sliding block (6210) and the second sliding block (628).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910893591.2A CN110596408A (en) | 2019-09-20 | 2019-09-20 | Full-automatic dry immunoassay equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910893591.2A CN110596408A (en) | 2019-09-20 | 2019-09-20 | Full-automatic dry immunoassay equipment |
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| Publication Number | Publication Date |
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| CN110596408A true CN110596408A (en) | 2019-12-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910893591.2A Pending CN110596408A (en) | 2019-09-20 | 2019-09-20 | Full-automatic dry immunoassay equipment |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114196516A (en) * | 2020-09-02 | 2022-03-18 | 浙江康是医疗器械有限公司 | Full-automatic portable virus sampling pipe rapid analysis equipment |
| WO2022217397A1 (en) * | 2021-04-12 | 2022-10-20 | 苏州鼎实医疗科技有限公司 | Fully automated immunoassay analyzer convenient for feeding and discharging |
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