CN219285208U - Sample pretreatment system - Google Patents

Sample pretreatment system Download PDF

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Publication number
CN219285208U
CN219285208U CN202223241190.5U CN202223241190U CN219285208U CN 219285208 U CN219285208 U CN 219285208U CN 202223241190 U CN202223241190 U CN 202223241190U CN 219285208 U CN219285208 U CN 219285208U
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Prior art keywords
feeding
pretreatment system
sample pretreatment
carrier
loading
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CN202223241190.5U
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Chinese (zh)
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吕彬
孙明明
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MGA Technology Shenzhen Co Ltd
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MGA Technology Shenzhen Co Ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The utility model relates to the technical field of sample detection and discloses a sample pretreatment system. The sample pretreatment system comprises a first feeding and discharging mechanism, a clamping mechanism, a bottle body clamping mechanism, a liquid transferring mechanism and an outer cover, wherein the first feeding and discharging mechanism is used for finishing feeding and discharging of a material tray, the first feeding and discharging mechanism comprises a first drawing structure, and the first drawing structure is used for placing the material tray and can drive the material tray to move along a preset direction; the clamping mechanism is used for clamping the material pipe from the first feeding and discharging mechanism and driving the material pipe to move between the feeding and discharging stations and the liquid taking station; the bottle body clamping mechanism is used for clamping or loosening the material pipe moving to the liquid taking station; one side of the outer cover is provided with a first openable door body. When the sample pretreatment system provided by the utility model is used, the loading and unloading process can be completed by opening the first door body and pulling the corresponding first pull type structure, so that the sample pretreatment system can be stopped without stopping or in a short time, the working efficiency is ensured, and the requirement of rapid detection is further met.

Description

Sample pretreatment system
Technical Field
The utility model relates to the technical field of sample detection, in particular to a sample pretreatment system.
Background
When the detection amount of samples such as organisms is increased under the condition of epidemic, the number of samples is greatly increased especially when the samples are applied to serious epidemic situations. The traditional sample adding link of nucleic acid extraction needs a great deal of time and effort to be put into by a tester, the burden of medical staff is increased, and the staff is exposed in dangerous environment for a long time, so that the health of the staff is not benefited, and the sample detection system needs to be developed. The cup separation pretreatment (cover opening and sample adding) of the nucleic acid sample is a working procedure with the largest workload in the nucleic acid detection, and takes 40% -60% of the whole detection flow, which is the largest bottleneck for restricting the nucleic acid detection speed. Breaking through the bottleneck, the detection task of the regional full-worker nucleic acid can be completed early, so as to quickly block the infectious chain. The shell of the existing automatic cup separating system mostly adopts a closed type, so that equipment is required to stop for a long time when loading and unloading are required, loading and unloading are waited, and restarting is performed after loading and unloading are completed, so that the efficiency is low, and the requirement of rapid detection cannot be met.
Disclosure of Invention
In order to solve the above technical problems or at least partially solve the above technical problems, the present utility model provides a sample pretreatment system.
The utility model provides a sample pretreatment system, comprising:
the first feeding and discharging mechanism is used for finishing feeding and discharging of a material tray for storing the material pipe and comprises a first drawing structure, and the first drawing structure is used for placing the material tray and can drive the material tray to move along a preset direction;
the clamping mechanism is used for clamping the material pipe from the first feeding and discharging mechanism and driving the material pipe to move between the feeding and discharging stations and the liquid taking station;
the bottle body clamping mechanism is used for clamping or loosening the material pipe moving to the liquid taking station;
the liquid transferring mechanism comprises a liquid transferring component used for moving liquid in a material pipe of the liquid taking station to a designated position;
the outer cover, unloading mechanism, clamp get the mechanism, body clamping mechanism and pipetting mechanism all are located in the outer cover, the outer cover is provided with openable first door body, the position of first door body and the opening of first door body all with first pull formula structure is corresponding.
Optionally, the first pull-out structure includes a first sliding substrate and a first carrier disposed above the first sliding substrate, the tray is disposed on the first carrier, and the first carrier is slidingly engaged with the first sliding substrate along the predetermined direction.
Optionally, the first feeding and discharging mechanism further includes:
a first base;
the first linear module is arranged on the first base and is used for driving the first sliding substrate to move along the preset direction.
Optionally, a side of the first bearing piece far away from the first door body of the outer cover is connected with the first base through a limiting mechanism.
Optionally, a first positioning hole is formed in the first bearing member, and the first sliding substrate is provided with:
the first positioning pin is arranged along the vertical direction;
the first driving piece is used for driving the first locating pin to move along the vertical direction, so that the first locating pin can be inserted into or separated from the first locating hole.
Optionally, the first loading and unloading mechanism further includes a limiting member configured to release or perform limiting of the tray on the first carrier.
Optionally, the limiting piece is disposed on the first bearing piece, and the limiting piece includes a limiting block and fixed blocks located at two sides of the limiting block, where the limiting block is configured to rotate relative to the fixed blocks, so as to release or execute limiting on the tray.
Optionally, the sample pretreatment system further comprises a second loading and unloading mechanism, wherein the second loading and unloading mechanism is used for loading and unloading a material box for storing a pipetting gun head and/or a target container for storing target liquid, the designated position is the position of the target container, and the second loading and unloading mechanism comprises a second drawing structure which is used for placing the material box and/or the target container; the pipetting assembly is used for taking out the pipetting gun head from the material box and sucking the liquid through the pipetting gun head;
the outer cover is also provided with a second door body which can be opened, and the position of the second door body and the opening of the second door body are corresponding to the second drawing structure.
Optionally, the second pull-out structure includes a second sliding base plate and a second carrier disposed above the second sliding base plate, on which the cartridge and/or the target container is placed, and the second carrier is slidably engaged with the second sliding base plate along the predetermined direction.
Optionally, the second feeding and discharging mechanism further includes:
a second base;
the second linear module is arranged on the second base and is used for driving the second sliding substrate to move along the preset direction.
Optionally, one side of the second base far away from the second door body of the outer cover is provided with a second locating pin arranged along the vertical direction, and a second driving piece for driving the second locating pin to move along the vertical direction, and the second bearing piece is provided with a second locating hole for the second locating pin to insert.
Optionally, a side of the second carrier remote from the second door of the housing is provided with an in-place sensor and configured to:
after the in-place sensor detects that the second bearing piece moves to a preset position, the second driving piece drives the second positioning pin to be inserted into the second positioning hole.
Optionally, a button and an indicator lamp are disposed at positions of the housing corresponding to the first door body and the second door body, and are configured to:
when the first feeding and discharging mechanism and/or the second feeding and discharging mechanism need to feed, the corresponding indicator lamp is lightened;
after the first feeding and discharging mechanism and/or the second feeding and discharging mechanism are reset, the indicator lamp is turned off, and a feeding completion signal can be sent by pressing the button.
Compared with the prior art, the technical scheme provided by the embodiment of the utility model has the following advantages:
according to the sample pretreatment system provided by the utility model, the openable first door body is arranged on the outer cover, the first pull-out structure which is arranged corresponding to the first door body is arranged on the first loading and unloading mechanism, and in the working process, the loading and unloading process can be completed by opening the first door body and pulling the corresponding first pull-out structure, so that the machine can be stopped without stopping or in a short time, the working efficiency is ensured, and the requirement of rapid detection is further met.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments consistent with the utility model and together with the description, serve to explain the principles of the utility model.
In order to more clearly illustrate the embodiments of the present utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it will be obvious to those skilled in the art that other drawings can be obtained from these drawings without inventive effort.
FIG. 1 is a schematic diagram of a sample pretreatment system according to an embodiment of the present utility model;
FIG. 2 is a schematic diagram of the sample pretreatment system according to the embodiment of the present utility model with the first door and the second door removed;
FIG. 3 is a schematic diagram of the sample pretreatment system according to the embodiment of the present utility model with the cover removed;
fig. 4 is a schematic structural diagram of a first feeding and discharging mechanism according to an embodiment of the present utility model;
fig. 5 is a schematic structural diagram of the first feeding and discharging mechanism with one tray removed according to the embodiment of the present utility model;
fig. 6 is a schematic structural diagram of a second feeding and discharging mechanism according to an embodiment of the present utility model;
fig. 7 is a schematic structural view of a pipetting assembly according to an embodiment of the utility model.
Description of the reference numerals
10. A first feeding and discharging mechanism; 11. a first base; 12. a first linear module; 13. a limiting mechanism; 14. a limiting block; 15. a fixed block; 20. a material tray; 30. a first pull-out structure; 31. a first sliding substrate; 32. a first carrier; 321. a first positioning hole; 322. a first clasp; 40. a clamping mechanism; 50. a bottle body clamping mechanism; 60. a pipetting mechanism; 61. a pipetting assembly; 70. an outer cover; 71. a first door body; 72. a second door body; 80. a second feeding and discharging mechanism; 81. a magazine; 82. a target container; 83. a second base; 831. a second positioning pin; 84. a second linear module; 90. a second pull-out structure; 91. a second sliding substrate; 911. an in-place sensor; 92. a second carrier; 921. a second positioning hole; 922. and a second buckle.
Detailed Description
In order that the above objects, features and advantages of the utility model will be more clearly understood, a further description of the utility model will be made. The embodiments of the present utility model and the features in the embodiments may be combined with each other without collision.
In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present utility model, but the present utility model may be practiced otherwise than as described herein; it is apparent that the embodiments in the specification are only some embodiments of the present utility model, but not all embodiments.
Referring to fig. 1 to 3, a sample pretreatment system according to an embodiment of the present utility model includes a first loading and unloading mechanism 10, a gripping mechanism 40, a body clamping mechanism 50, a pipetting mechanism 60 and a housing 70.
The first loading and unloading mechanism 10 is used for finishing loading and unloading of the tray 20 for storing the material pipe, the first loading and unloading mechanism 10 comprises a first drawing structure 30, and the first drawing structure 30 is used for placing the tray 20 and can drive the tray 20 to move along a preset direction. The preset direction is the Y-axis direction shown in FIG. 3. The clamping mechanism 40 is used for clamping the material pipe from the first feeding and discharging mechanism 10 and driving the material pipe to move between the feeding and discharging stations and the liquid taking station. The body gripping mechanism 50 is used to grip or release a tube that is moved to the tapping station. The pipetting mechanism 60 comprises a pipetting assembly 61 for moving liquid in the tube of the pipetting station to a specified position. As shown in fig. 2, the first loading and unloading mechanism 10, the clamping mechanism 40, the bottle body clamping mechanism 50 and the pipetting mechanism 60 are all located in the outer cover 70, the outer cover 70 is provided with a first openable door 71, and the position of the first door 71 and the opening of the first door 71 correspond to the first pull-out structure 30.
According to the sample pretreatment system provided by the utility model, the openable first door body 71 is arranged on the outer cover 70, and the first pull-out structure 30 which is arranged corresponding to the first door body 71 is arranged on the first loading and unloading mechanism 10, in the working process, the loading and unloading process can be completed by opening the first door body 71 and pulling the corresponding first pull-out structure 30, so that the machine can be stopped without stopping or in a short time, the working efficiency is ensured, and the requirement of rapid detection is further met.
As shown in fig. 4, the first pull-out structure 30 includes a first sliding base plate 31 and a first carrier 32 disposed above the first sliding base plate 31, the tray 20 is placed on the first carrier 32, and the first carrier 32 is slidably engaged with the first sliding base plate 31 along a predetermined direction. Because the first pull-out structure 30 is opposite to the first door 71, when the tray 20 is replaced, the corresponding first door 71 can be opened, and the first carrier 32 is pulled to drive the tray 20 to move along the direction towards the first door 71 until the tray 20 extends out of the outer cover 70, so that the tray 20 is convenient to replace. Further preferably, a first buckle 322 is disposed on a side of the first carrier 32 near the first door 71, so that a worker can perform the pulling operation by the first buckle 322, thereby increasing the convenience of operation.
As shown in fig. 4 and 5, the first loading and unloading mechanism 10 further includes a first base 11 and a first linear module 12. The first linear module 12 is arranged on the first base 11, and the first base 11 is arranged on the frame, wherein an arc hole can be formed in the first base 11, the first base 11 is arranged on the frame through the arc hole by a fastener, the position of the whole first feeding and discharging mechanism 10 can be adjusted through the arc hole, and the position of the clamping jaw of the first feeding and discharging mechanism 10 and the clamping jaw of the clamping mechanism 40 are opposite. The first linear module 12 is configured to drive the first sliding substrate 31 to move along a predetermined direction. Under this design, the stroke of the tray 20 is divided into two sections, and the first section of stroke drives the first sliding substrate 31 to move towards the first door 71 through the first linear module 12 until the first sliding substrate 31, the first bearing member 32 located above the first sliding substrate 31, and the tray 20 move to a position inside the housing 70 near the first door 71. At this time, the first linear module 12 stops working, the worker opens the first door 71, and pulls the first buckle 322 by hand, so as to pull the first carrier 32 and the tray 20 to extend out of the outer cover 70, thereby completing the replacement process of the tray 20, improving the loading and unloading efficiency, increasing the stroke of the tray 20, and increasing the convenience of operation. In addition, the tray 20 has 8 holes along the Y axis, and the gripping mechanism 40 can only grip 4 tubes at a time and can only move along the X axis, so that the movement of the tray 20 along the Y axis can ensure that the gripping mechanism 40 can grip another 4 tubes.
The side of the first carrier 32 far from the first door body 71 of the housing 70 is connected with the first base 11 through a limiting mechanism 13. The position of the first bearing piece 32 in the non-reloading state is limited by the limiting mechanism 13, so that the first bearing piece 32 is prevented from moving in the working process, and the limitation of the first bearing piece 32 can be relieved by the limiting mechanism 13 in the reloading state, so that the first linear module 12 can conveniently drive the first linear module 12 and the first bearing piece 32 to move. Further preferably, one side of the first carrier 32 far away from the first door body 71 of the housing 70 is connected with the first sliding substrate 31 on the first base 11 through the limiting mechanism 13, wherein the first sliding substrate 31 is positioned through the first linear module 12, and the first carrier 32 and the first sliding substrate 31 are positioned through the limiting mechanism 13, so that the stability of the first carrier 32 can be ensured.
In some embodiments, the spacing mechanism 13 may be a magnetic assembly. Specifically, the magnetic assembly includes a first magnet disposed on the first carrier 32 and a second magnet disposed on the first base 11 or the first sliding substrate 31, and the first magnet and the second magnet attract each other, so that when the first carrier 32 moves to a position close to the second magnet, the first carrier 32 can be attached to a sidewall of the first base 11 or the first sliding substrate 31 by an attractive force between the first magnet and the second magnet. And the first bearing member 32 can be separated from the first base 11 or the first sliding substrate 31 under the action of external force.
In other embodiments, the limiting mechanism 13 may also be a buckle assembly, and specifically may include a slot disposed on the first carrier 32 and a buckle disposed on the first base 11 or the first sliding substrate 31, where the slot is matched with the buckle. When the buckle is arranged on the first sliding substrate 31, the first bearing piece 32 can be pushed manually, so that the clamping groove is clamped on the buckle of the first sliding substrate 31, or the first bearing piece 32 is separated from the first sliding substrate 31 by pulling the first bearing piece 32. When the buckle is disposed on the first base 11, the first bearing member 32 can be driven to attach to or detach from the first base 11 by the movement of the first linear module 12.
Therefore, the specific setting mode of the limiting mechanism 13 is not limited, and only the setting of the limiting mechanism 13 needs to be ensured so that the first linear module 12 is disconnected when driving the first sliding substrate 31 and the first bearing member 32 to move, thereby avoiding affecting the work of the first linear module 12.
As shown in fig. 5, the first carrier 32 is provided with a first positioning hole 321, and the first sliding base 31 is provided with a first positioning pin and a first driving member. The first positioning pin is arranged along the vertical direction. The first driving member is configured to drive the first positioning pin to move along a vertical direction, so that the first positioning pin can be inserted into or separated from the first positioning hole 321, so as to facilitate positioning of the first carrier 32 and the tray 20.
As shown in fig. 4, the first loading and unloading mechanism 10 further includes a limiting member configured to release or perform limiting of the tray 20 on the first carrier 32, so as to facilitate positioning of the tray 20. Specifically, the limiting member is disposed on the first carrier 32, and the limiting member includes a limiting block 14 and fixing blocks 15 disposed at two sides of the limiting block 14, where the limiting block 14 is configured to be rotatable relative to the fixing blocks 15 to release or perform limiting of the tray 20. Specifically, when the tray 20 is required to be limited, the limiting block 14 and the two fixing blocks 15 are relatively fixed, the limiting block 14 can be fixed by adopting a bolt and other structures, when the tray 20 is required to be replaced, the limitation is released, the limiting block 14 is operated, the limiting block 14 rotates relative to the fixing blocks 15, and the limiting block 14 is separated from the side face of the tray 20, so that the tray 20 can be replaced. The design mode is simple in structure and convenient to operate, the convenience of replacing the material tray 20 is improved, and the stability of the material tray 20 in the use process is ensured.
In some preferred embodiments, the first loading and unloading mechanisms 10 are at least two groups, and at least two groups of the first loading and unloading mechanisms 10 are arranged in parallel along the X-axis direction. Under this kind of design mode, when one of them charging tray 20 participated in the operation, can change another charging tray 20, and then can accomplish the unloading on the circulation of not shutting down, further ensures work efficiency.
As shown in fig. 2, 3 and 6, the sample pretreatment system further includes a second loading and unloading mechanism 80, where the second loading and unloading mechanism 80 is used to complete loading and unloading of the cartridge 81 storing the pipette tip and/or the target container 82 storing the target liquid, and the designated position is the position of the target container 82. The second feeding and discharging mechanism 80 includes a second pull-out structure 90, where the second pull-out structure 90 is used to place the material box 81 and/or the target container 82, and the second pull-out structure 90 can drive the material box 81 and/or the target container 82 to move along the Y-axis direction. The pipetting assembly 61 is used to withdraw the pipette tip from the cartridge 81, aspirate liquid through the pipette tip, and discharge the withdrawn liquid into the target container 82. Wherein the target container 82 is preferably a deep hole plate. As shown in fig. 1, the cover 70 is further provided with a second openable door 72, and the position of the second door 72 and the opening of the second door 72 correspond to the second pull-out structure 90.
The sample pretreatment system in this design mode is provided with a first door body 71 and a second door body 72 which can be opened on the outer cover 70, and a first pull-out structure 30 and a second pull-out structure 90 which are correspondingly arranged with the first door body 71 and the second door body 72 are respectively arranged on the first loading and unloading mechanism 10 and the second loading and unloading mechanism 80. In the working process, the corresponding first door body 71 and/or the second door body 72 can be opened, the corresponding first pull type structure 30 and/or the second pull type structure can be pulled to complete the feeding and discharging process, the machine can be stopped without stopping or in a short time, the working efficiency is ensured, and the requirement of rapid detection is further met.
As shown in fig. 6, the second pull-out structure 90 includes a second sliding base 91 and a second carrier 92 disposed above the second sliding base 91, where the magazine 81 and/or the target container 82 are placed on the second carrier 92, and the second carrier 92 is slidably engaged with the second sliding base 91 along a predetermined direction, which is the Y-axis direction in fig. 3. Since the second pull structure 90 is opposite to the second door 72, when the cartridge 81 and/or the target container 82 are replaced, the corresponding second door 72 can be opened, and by pulling the second carrier 92, the second carrier 92 can drive the cartridge 81 and/or the target container 82 to move along the direction towards the second door 72 until the cartridge 81 and/or the target container 82 protrudes out of the housing 70, so that replacement of the cartridge 81 and/or the target container 82 is facilitated. Further preferably, a second buckle 922 is disposed on a side of the second bearing member 92 close to the second door 72, and a worker can perform the pulling operation through the second buckle 922, so as to increase the convenience of operation.
The second loading and unloading mechanism 80 further includes a second base 83 and a second linear module 84. The second linear module 84 is disposed on the second base 83, and the second base 83 is disposed on the frame, and the second linear module 84 is used for driving the second sliding substrate 91 to move along a predetermined direction. In this design manner, the stroke of the magazine 81 and/or the target container 82 is divided into two sections, and the first section of stroke drives the second sliding substrate 91 to move towards the second door 72 through the second linear module 84 until the second sliding substrate 91 and the second bearing 92 above the second sliding substrate 91 and the magazine 81 and/or the target container 82 move to a position inside the housing 70 near the second door 72. At this time, the second linear module 84 stops working, the worker opens the second door 72, and pulls the second bearing member 92 and the material box 81 and/or the target container 82 out of the outer cover 70 by pulling the second button 922, so as to complete the replacement process of the material box 81 and/or the target container 82, improve the loading and unloading efficiency, increase the travel of the material box 81 and/or the target container 82, and increase the convenience of operation.
The second base 83 is provided with a second positioning pin 831 disposed along a vertical direction on a side of the second door 72 away from the housing 70, and a second driving member for driving the second positioning pin 831 to move along the vertical direction, and the second bearing member 92 is provided with a second positioning hole 921 into which the second positioning pin 831 can be inserted. Wherein, the second positioning pin 831 and the second driving member may also be disposed on the second sliding substrate 91 of the second base 83.
Under this kind of design mode, after the second carrier 92 moved in place, the accessible second driving piece drove second locating pin 831 and stretches out, and then makes second locating pin 831 insert in the second locating hole 921, accomplishes the location of second carrier 92, avoids the in-process of working, and second carrier 92 and the magazine 81 and/or the target container 82 that are in its top rock. In addition, when the cartridge 81 and/or the target container 82 need to be replaced, the second driving member drives the second positioning pin 831 to disengage from the second positioning hole 921, so as to facilitate movement of the second bearing member 92.
Further preferably, the second sliding substrate 91 is provided with a ball striking mechanism, a limiting hole matched with the ball striking mechanism is arranged below the second bearing member 92, and after the second bearing member 92 moves in place, the ball striking of the ball striking mechanism is clamped in the limiting hole.
The second carrier 92 is provided with an in-place sensor 911 at a side thereof remote from the second door 72 of the housing 70, and specifically, after the in-place sensor 911 detects that the second carrier 92 moves to a preset position, the second driving member drives the second positioning pin 831 to be inserted into the second positioning hole 921. The preset position is a position where the second bearing member 92 moves to a position where the second positioning hole 921 is opposite to the second positioning pin 831.
In some preferred embodiments, the second loading and unloading mechanisms 80 are at least two groups, and the plurality of groups of second loading and unloading mechanisms 80 are arranged in parallel along the X-axis direction. Under the design mode, when one group of the material boxes 81 and/or the target containers 82 participate in the operation, the other group of the material boxes 81 and/or the target containers 82 can be replaced, so that the material loading and unloading can be performed without stopping the machine, and the working efficiency is further ensured.
Taking two groups of first loading and unloading mechanisms 10 and second loading and unloading mechanisms 80 as examples, the sample pretreatment system in the design mode comprises two trays 20, two cartridges 81 and two target containers 82, wherein one cartridge 81 and one target container 82 are one group, and are placed on one second drawing structure 90. The design mode can realize the whole-course non-stop cyclic loading and unloading, and the drawing structure can realize the rapid loading and unloading, thereby ensuring the working efficiency of the sample pretreatment system. The four-channel technology is adopted, the high-flux mechanical arm has the advantage of high flux, and the traditional mechanical arm is replaced by the module, so that the four-channel mechanical arm has the advantage of low price.
In addition, the first driving piece and the second driving piece of the present application respectively adopt double guide rod cylinders, and the first positioning pin and the first positioning hole 321 and the first positioning pin and the second positioning hole 921 are matched, so that the positioning of the first bearing piece 32 and the second bearing piece 92 can be ensured to be firm and reliable.
The buttons and the indicator lamps are arranged at positions of the outer cover 70 corresponding to the first door body 71 and the second door body 72, and when the first feeding and discharging mechanism 10 and/or the second feeding and discharging mechanism 80 need to feed materials, the corresponding indicator lamps are turned on. After the first feeding and discharging mechanism 10 and/or the second feeding and discharging mechanism 80 after feeding are reset, the indicator lamp is turned off, and a feeding completion signal can be sent by pressing a button. In addition, a touch screen may be provided on the housing 70 to facilitate control of the operating state of the sample pretreatment system.
As shown in fig. 7, the pipetting module 61 is a conventional part for pipetting in the art, which can move in the X-axis direction, the Y-axis direction and the Z-axis direction, grasp the pipetting gun head, and suck liquid through the pipetting gun head, and the like, and since it is a conventional device and is not a protection point of the present application, the structure and the working principle of the pipetting module 61 are not described too much here.
The sample pretreatment system with the design mode is mainly used for providing pretreatment for samples during virus detection, and specifically, for example, the sample pretreatment system provided by the scheme can be used for transferring the samples in the throat swab pipe to a designated target container 82 (such as a deep pore plate), and operations such as cover opening and closing, code scanning and the like are required to be performed on the throat swab pipe in the process. Specifically, the clamping mechanism 40 clamps the pharyngeal swab tube from the tray 20, and simultaneously a code reader on the clamping mechanism 40 reads a one-dimensional code or a two-dimensional code on the pharyngeal swab tube, the clamping mechanism 40 then places the pharyngeal swab tube at the position of the bottle body clamping mechanism 50, and performs the uncapping of the pharyngeal swab tube, and after the pipetting mechanism 60 pipetting, the cap is closed, and then the pharyngeal swab tube is clamped and placed back into the tray 20.
It should be noted that in this document, relational terms such as "first" and "second" and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
The foregoing is only a specific embodiment of the utility model to enable those skilled in the art to understand or practice the utility model. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the utility model. Thus, the present utility model is not intended to be limited to the embodiments shown and described herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims (13)

1. A sample pretreatment system, comprising:
the feeding and discharging device comprises a first feeding and discharging mechanism (10) for finishing feeding and discharging of a material tray (20) for storing a material pipe, wherein the first feeding and discharging mechanism (10) comprises a first drawing structure (30), and the first drawing structure (30) is used for placing the material tray (20) and can drive the material tray to move along a preset direction;
the clamping mechanism (40) is used for clamping the material pipe from the first feeding and discharging mechanism (10) and driving the material pipe to move between the feeding and discharging stations and the liquid taking station;
the bottle body clamping mechanism (50) is used for clamping or loosening the material pipe moving to the liquid taking station;
a pipetting mechanism (60) comprising a pipetting assembly (61) for moving liquid in a tube of the pipetting station to a designated position;
the outer cover (70), unloading mechanism (10), clamp and get mechanism (40), body clamping mechanism (50) and pipetting mechanism (60) all are located in outer cover (70), outer cover (70) are provided with openable first door body (71), the position of first door body (71) and the opening of first door body (71) all with first pull formula structure (30) are corresponding.
2. The sample pretreatment system according to claim 1, wherein said first drawer structure (30) comprises a first sliding base plate (31) and a first carrier (32) arranged above said first sliding base plate (31), said tray (20) being placed on said first carrier (32), said first carrier (32) being in sliding engagement with said first sliding base plate (31) along said predetermined direction.
3. The sample pretreatment system according to claim 2, wherein said first loading and unloading mechanism (10) further comprises:
a first base (11);
the first linear module (12), the first linear module (12) is arranged on the first base (11), and the first linear module (12) is used for driving the first sliding substrate (31) to move along the preset direction.
4. A sample pretreatment system according to claim 3, wherein a side of the first carrier (32) remote from the first door (71) of the housing (70) is connected to the first base (11) by a limiting mechanism (13).
5. The sample pretreatment system according to claim 2, wherein the first carrier (32) is provided with a first positioning hole (321), and the first slide substrate (31) is provided with:
the first positioning pin is arranged along the vertical direction;
and the first driving piece is used for driving the first positioning pin to move along the vertical direction so that the first positioning pin can be inserted into or separated from the first positioning hole (321).
6. The sample pretreatment system according to claim 2, wherein said first loading and unloading mechanism (10) further comprises a stop configured to enable release or execution of the stop of said tray (20) on said first carrier (32).
7. The sample pretreatment system according to claim 6, wherein the stopper is provided on the first carrier (32), the stopper comprises a stopper (14) and fixed blocks (15) located on both sides of the stopper (14), the stopper (14) is configured to be rotatable with respect to the fixed blocks (15) to release or perform the stopper of the tray (20).
8. Sample pretreatment system according to any of claims 1 to 7, further comprising a second loading and unloading mechanism (80), wherein the second loading and unloading mechanism (80) is used for loading and unloading a cartridge (81) for storing a pipette tip and/or a target container (82) for storing a target liquid, the designated position is the position of the target container (82), the second loading and unloading mechanism (80) comprises a second drawing structure (90), and the second drawing structure (90) is used for placing the cartridge (81) and/or the target container (82); -the pipetting assembly (61) is adapted to withdraw the pipette tip from the cartridge (81) and to aspirate the liquid through the pipette tip;
the outer cover (70) is further provided with a second door body (72) which can be opened, and the position of the second door body (72) and the opening of the second door body (72) are corresponding to the second drawing structure (90).
9. Sample pretreatment system according to claim 8, characterized in that the second pull-out structure (90) comprises a second sliding base plate (91) and a second carrier (92) arranged above the second sliding base plate (91), the cartridge (81) and/or the target container (82) being placed on the second carrier (92), the second carrier (92) being in sliding engagement with the second sliding base plate (91) along the predetermined direction.
10. The sample pretreatment system of claim 9, wherein said second loading and unloading mechanism (80) further comprises:
a second base (83);
the second linear module (84), the second linear module (84) is arranged on the second base (83), and the second linear module (84) is used for driving the second sliding substrate (91) to move along the preset direction.
11. The sample pretreatment system according to claim 10, wherein a side of the second base (83) remote from the second door body (72) of the housing (70) is provided with a second positioning pin (831) arranged in a vertical direction, and a second driving member for driving the second positioning pin (831) to move in the vertical direction, and the second bearing member (92) is provided with a second positioning hole (921) into which the second positioning pin (831) is inserted.
12. The sample pretreatment system according to claim 11, wherein a side of the second carrier (92) remote from the second door (72) of the housing (70) is provided with an in-place sensor (911) and is configured to:
after the in-place sensor (911) detects that the second bearing member (92) moves to a preset position, the second driving member drives the second positioning pin (831) to be inserted into the second positioning hole (921).
13. The sample pretreatment system according to claim 8, wherein the housing (70) is provided with buttons and indicator lights at positions corresponding to the first door (71) and the second door (72), and is configured to:
when the first feeding and discharging mechanism (10) and/or the second feeding and discharging mechanism (80) need to feed, the corresponding indicator lamp is lighted;
after the first feeding and discharging mechanism (10) and/or the second feeding and discharging mechanism (80) are reset, the indicator lamp is turned off, and a feeding completion signal can be sent by pressing the button.
CN202223241190.5U 2022-12-02 2022-12-02 Sample pretreatment system Active CN219285208U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202223241190.5U CN219285208U (en) 2022-12-02 2022-12-02 Sample pretreatment system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202223241190.5U CN219285208U (en) 2022-12-02 2022-12-02 Sample pretreatment system

Publications (1)

Publication Number Publication Date
CN219285208U true CN219285208U (en) 2023-06-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202223241190.5U Active CN219285208U (en) 2022-12-02 2022-12-02 Sample pretreatment system

Country Status (1)

Country Link
CN (1) CN219285208U (en)

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