CN220846120U - Genotype detection kit for polymorphic locus of folic acid metabolism gene - Google Patents

Genotype detection kit for polymorphic locus of folic acid metabolism gene Download PDF

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Publication number
CN220846120U
CN220846120U CN202322544072.XU CN202322544072U CN220846120U CN 220846120 U CN220846120 U CN 220846120U CN 202322544072 U CN202322544072 U CN 202322544072U CN 220846120 U CN220846120 U CN 220846120U
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fixed
kit
wall
folic acid
metabolism gene
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CN202322544072.XU
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张萌媛
张茂好
张晓峰
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Shandong Fuyou Life Sciences Co ltd
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Shandong Fuyou Life Sciences Co ltd
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Abstract

The utility model relates to a genotype detection kit for folic acid metabolic gene polymorphism sites, which comprises a kit body, wherein a double-shaft linear module is fixed on the inner top wall of the kit body, a detection mechanism is arranged at the bottom end of the double-shaft linear module and is used for carrying out multi-position sampling detection on folic acid metabolic gene samples, a partition plate is fixed between the left inner wall and the right inner wall of the kit body, an installation groove is formed in the front surface of the partition plate, and a feeding mechanism is arranged in the installation groove so as to facilitate the operation of the samples. This genotype detection kit of folic acid metabolism gene polymorphism site through the cooperation of biax sharp module, can drive first electric putter and remove to adjust the position of taking a sample, first electric putter's cooperation can drive the installation piece and remove, thereby conveniently draws the sample, through the cooperation of second electric putter, can drive the connecting rod and remove, thereby drive push pedal and sealed the pad and remove, thereby draw folic acid metabolism gene.

Description

Genotype detection kit for polymorphic locus of folic acid metabolism gene
Technical Field
The utility model relates to the technical field of gene detection, in particular to a genotype detection kit for polymorphic loci of folic acid metabolism genes.
Background
Folic acid is a water-soluble B-group vitamin consisting of pteridine, para-aminobenzoic acid and glutamic acid residues, also called vitamin BC or vitamin M, which is a substance necessary for the growth and reproduction of cells of the organism, helps the metabolism of proteins, and promotes the generation and maturation of erythrocytes together with vitamin B12, which is an indispensable substance for the production of erythrocytes.
As disclosed in chinese patent publication No. (CN 211595661U), an EGFR genotype detection kit is disclosed, which comprises a box body, the left end of the upper surface of the box body is provided with a rotary button, the right side of the rotary button is provided with an additive reagent button, the right side of the additive reagent button is provided with a display, the right side of the display is provided with a data processing button, the left end of the data processing button is provided with a switch, the left end of the inner side of the upper surface of the box body is provided with a rotor seat, the lower end of the rotor seat is provided with a dropper and a test tube plug, a stepping motor is arranged in the rotor seat, the inner side of the lower surface of the box body is provided with a turntable seat, the inside of the turntable seat is provided with a turntable motor, the turntable motor is electrically connected with the rotary button, the upper end of the turntable is provided with a spectrum receiver, the right side of the spectrum receiver is provided with a test tube placement hole, the right side of the test tube placement hole is provided with a fluorescent tube, the front end and the rear end of the display are symmetrically provided with a heating group, the rear end of the box body is provided with a circuit board, the upper end of the circuit board is provided with a reagent box, the utility model has a mutation subunit affects the stability of the tetramer, the performance of the sample cannot be normally influenced, and the performance of the sample cannot be normally detected due to the situation of the expression of the enzyme is different, but the sample cannot be normally influenced.
Disclosure of utility model
Aiming at the defects of the prior art, the utility model provides a genotype detection kit for polymorphic loci of folic acid metabolism genes, which has the advantages of carrying out detection for multiple times and avoiding limitation in detection, and solves the problems that the detection result has specificity and limitation and the practicability is influenced because folic acid metabolism gene samples at different positions cannot be extracted in the patent.
In order to achieve the above purpose, the present utility model provides the following technical solutions: the genotype detection kit for the folic acid metabolism gene polymorphism sites comprises a kit body, wherein a double-shaft linear module is fixed on the inner top wall of the kit body, a detection mechanism is arranged at the bottom end of the double-shaft linear module and used for carrying out multi-position sampling detection on folic acid metabolism gene samples, a partition plate is fixed between the left inner wall and the right inner wall of the kit body, an installation groove is formed in the front surface of the partition plate, and a feeding mechanism is arranged in the installation groove and is convenient for operating the samples;
The detection mechanism comprises a first electric push rod fixed at the bottom end of the double-shaft linear module, an output shaft of the first electric push rod is fixedly provided with a mounting block, an extraction assembly is arranged in the mounting block, a heat insulation pad is fixed on the left inner wall of the kit body, a heating plate is fixed on the right side of the heat insulation pad, and an electric heating wire is fixed on the inner side of the heating plate.
Further, the back of kit body is articulated through the articulated shaft has the baffle, the back of baffle is fixed with the handle.
Further, the number of the heat insulation pads is two, and the heat insulation pads are distributed in a bilateral symmetry mode through the central axis of the kit body.
Further, draw the subassembly including fixing the sampling tube at the installation piece lower surface, the interior bottom wall of installation piece is fixed with second electric putter, second electric putter's output shaft runs through the interior bottom wall of installation piece and extends to the inside of sampling tube, and is fixed with the connecting rod, the bottom mounting of connecting rod has the push pedal, the outside of push pedal is fixed with sealed pad.
Further, the outer diameter of the push plate is equal to the inner diameter of the sealing gasket, and the outer diameter of the sealing gasket is matched with the inner diameter of the sampling tube.
Further, feed mechanism is including fixing the fixed block at the left side inner wall of mounting groove, be fixed with the slide bar between the back of fixed block and the back inner wall of mounting groove, the outside sliding connection of slide bar has the connecting plate, the front of connecting plate is fixed with places the platform, the front of placing the platform is fixed with the backup pad, the front of backup pad is fixed with the handle, the upper surface of placing the platform is fixed with places the seat, the upper surface of placing the platform is fixed with the detection platform.
Further, the front of kit body has seted up the opening, the backup pad is located the inside of opening, and the length and the width of backup pad respectively with open-ended length and width looks adaptation.
Compared with the prior art, the technical scheme of the application has the following beneficial effects:
1. This genotype detection kit of folic acid metabolism gene polymorphism site through the cooperation of biax sharp module, can drive first electric putter and remove to adjust the position of taking a sample, first electric putter's cooperation can drive the installation piece and remove, thereby conveniently draws the sample, through the cooperation of second electric putter, can drive the connecting rod and remove, thereby drive push pedal and sealed the pad and remove, thereby draw folic acid metabolism gene.
2. This genotype detection kit of folic acid metabolism gene polymorphism site through the cooperation of handle, can drive the backup pad and remove to drive and place the platform and remove, so that to placing seat and detecting the platform and remove, conveniently operate, through the cooperation of slide bar, can lead the removal orbit of connecting plate, thereby avoid placing the position of platform and take place the skew.
Drawings
FIG. 1 is a schematic diagram of the structure of the present utility model;
FIG. 2 is a partial schematic view of the structure of the present utility model;
FIG. 3 is a schematic diagram of a detection mechanism according to the present utility model;
FIG. 4 is a schematic view of a portion of a detection mechanism according to the present utility model;
FIG. 5 is a schematic view of the feeding mechanism of the present utility model.
In the figure: 1 a reagent box body, 2a double-shaft linear module, 3 a detection mechanism, 301 a first electric push rod, 302 a mounting block, 303 a heat insulation pad, 304 a heating plate, 305 a heating wire, 306 a sampling tube, 307 a second electric push rod, 308 a connecting rod, 309 a push plate, 310 a sealing pad, 4 a partition plate, 5a mounting groove, 6 a feeding mechanism, 601 a slide bar, 602 a connecting plate, 603 a placing table, 604 a supporting plate, 605 a handle, 606 a placing seat, 607 a detection table, 7 a baffle plate and 8 handles.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-2, a genotype detection kit for a polymorphic site of a folate metabolism gene in this embodiment includes a kit body 1, wherein a biaxial linear module 2 is fixed on an inner top wall of the kit body 1, a detection mechanism 3 is arranged at a bottom end of the biaxial linear module 2 for performing multi-position sampling detection on a folate metabolism gene sample, limitations of detection results are avoided, a partition board 4 is fixed between a left inner wall and a right inner wall of the kit body 1, an installation groove 5 is provided on a front surface of the partition board 4, a feeding mechanism 6 is provided in the installation groove 5, so that the sample is convenient to operate, take out and put in, cleaning of detection equipment is facilitated, and detection efficiency is improved.
Wherein, the back of kit body 1 articulates through the articulated shaft has baffle 7, and the back of baffle 7 is fixed with handle 8, can be convenient for open baffle 7 through handle 8 to make things convenient for the staff to overhaul the inside equipment of kit body 1.
Referring to fig. 3-4, in order to avoid limitation of detection results, the detection mechanism 3 in this embodiment includes a first electric push rod 301 fixed at the bottom end of a dual-shaft linear module 2, the dual-shaft linear module 2 drives the first electric push rod 301 to move so as to adjust the sampling position, an output shaft of the first electric push rod 301 is fixed with a mounting block 302, the output shaft of the first electric push rod 301 drives the mounting block 302 to move, an extraction component is disposed in the mounting block 302, a heat insulation pad 303 is fixed on the left inner wall of the reagent box body 1, a heating plate 304 is fixed on the right side of the heat insulation pad 303, an electric heating wire 305 is fixed on the inner side of the heating plate 304, a temperature sensor is fixed on the inner wall of the reagent box body 1, and the temperature inside the reagent box body 1 can be adjusted through the electric heating wire 305 and the heating plate 304 so as to adapt to the living environment of the sample.
In this example, the number of the heat insulation pads 303 is two, and the heat insulation pads 303 are symmetrically distributed about the central axis of the kit body 1, so that the internal temperature of the kit body 1 is uniformly distributed, and the heat insulation pads 303 can avoid the temperature from being transferred to the surface of the kit body 1.
It should be noted that, the extraction component includes the sampling tube 306 that is fixed at the lower surface of the installation piece 302, the installation piece 302 moves and drives the sampling tube 306 to move, the inner bottom wall of the installation piece 302 is fixed with the second electric putter 307, the output shaft of the second electric putter 307 runs through the inner bottom wall of the installation piece 302 and extends to the inside of the sampling tube 306, and is fixed with the connecting rod 308, the output shaft of the second electric putter 307 drives the connecting rod 308 to move, the bottom end of the connecting rod 308 is fixed with the push plate 309, the connecting rod 308 drives the push plate 309 to move, the outside of the push plate 309 is fixed with the sealing pad 310, the push plate 309 drives the sealing pad 310 to move, the sealing pad 310 moves upwards, so that the air pressure in the sampling tube 306 is reduced, thereby folic acid metabolic genes enter into the inside of the sampling tube 306, the outer diameter of the push plate 309 is equal to the inner diameter of the sealing pad 310, the outer diameter of the sealing pad 310 is matched with the inner diameter of the sampling tube 306, and air pressure leakage in the sampling tube 306 is avoided.
Referring to fig. 5, in order to facilitate taking out and putting in a sample, and cleaning the detection device, and improve the detection efficiency, the feeding mechanism 6 in this embodiment includes a fixing block fixed on the left inner wall of the installation groove 5, a sliding rod 601 fixed between the back of the fixing block and the rear inner wall of the installation groove 5, a connecting plate 602 slidably connected to the outer side of the sliding rod 601, the connecting plate 602 sliding on the outer side of the sliding rod 601 limiting the moving track of the connecting plate 602, a placing table 603 fixed on the front of the connecting plate 602, a supporting plate 604 fixed on the front of the placing table 603, a handle 605 driving the supporting plate 604 to move, a placing table 603 driving the placing table 603 to move, a placing seat 606 fixed on the upper surface of the placing table 603, a detection table 607 driving the placing seat 606 and the detection table 607 to move, placing a culture dish of a folate metabolic gene into the placing seat 606, and then placing the placing table 603 back into the inside of the reagent kit body 1, so as to perform the detection work.
In this example, the front of the kit body 1 is provided with an opening, the supporting plate 604 is located inside the opening, and the length and the width of the supporting plate 604 are respectively matched with the length and the width of the opening, the supporting plate 604 seals the opening, so that the interference of the external environment to the detection operation inside the kit body 1 is avoided.
The working principle of the embodiment is as follows:
(1) Between detection works, the handle 605 is pulled first, the handle 605 drives the supporting plate 604 to move, the supporting plate 604 drives the placing table 603 to move, the placing table 603 drives the placing seat 606 and the detecting table 607 to move, after the placing seat 606 and the detecting table 607 are moved out, the culture dish of the folic acid metabolism genes is placed in the placing seat 606, then the placing table 603 is placed back into the reagent box body 1, the placing table 603 slides outside the sliding rod 601 in the moving process, the sliding rod 601 limits the moving track of the connecting plate 602, and the position of the placing table 603 is prevented from shifting.
(2) After the placing table 603 is put back into the reagent box body 1, the double-shaft linear module 2 is opened, the double-shaft linear module 2 moves the first electric push rod 301 to the upper side of the placing seat 606, the first electric push rod 301 is opened, the output shaft of the first electric push rod 301 drives the mounting block 302 to move, the mounting block 302 drives the sampling tube 306 to move, the sampling tube 306 is enabled to be in contact with a culture dish, the second electric push rod 307 is opened at the moment, the output shaft of the second electric push rod 307 drives the connecting rod 308 to move, the connecting rod 308 drives the push plate 309 to move, the sealing gasket 310 is enabled to move upwards, the air pressure in the sampling tube 306 is reduced, so that folic acid metabolic genes enter the inside of the sampling tube 306, the double-shaft linear module 2 is opened again, the first electric push rod 301 is moved to the upper side of the detecting table 607, an extracted sample is dripped on the detecting table 607, meanwhile, the double-shaft linear module 2 returns to the upper side of the placing seat 606, the sampling position is adjusted, and the detection is carried out for multiple times, and therefore limitation of detection results is avoided.
It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising one … …" does not exclude the presence of other like elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made hereto without departing from the spirit and principles of the present utility model.

Claims (7)

1. The utility model provides a genotype detection kit of folic acid metabolism gene polymorphic site, includes kit body (1), its characterized in that: the kit comprises a kit body (1), wherein a double-shaft linear module (2) is fixed on the inner top wall of the kit body (1), a detection mechanism (3) is arranged at the bottom end of the double-shaft linear module (2) and used for carrying out multi-position sampling detection on folic acid metabolic gene samples, a partition board (4) is fixed between the left inner wall and the right inner wall of the kit body (1), an installation groove (5) is formed in the front surface of the partition board (4), and a feeding mechanism (6) is arranged in the installation groove (5) so as to facilitate the operation on the samples;
The detection mechanism (3) comprises a first electric push rod (301) fixed at the bottom end of the double-shaft linear module (2), an output shaft of the first electric push rod (301) is fixedly provided with a mounting block (302), an extraction assembly is arranged in the mounting block (302), a heat insulation pad (303) is fixed on the left inner wall of the kit body (1), a heating plate (304) is fixed on the right side of the heat insulation pad (303), and an electric heating wire (305) is fixed on the inner side of the heating plate (304).
2. The genotyping kit for polymorphic loci of a folate metabolism gene according to claim 1, wherein: the back of the kit body (1) is hinged with a baffle (7) through a hinge shaft, and a handle (8) is fixed on the back of the baffle (7).
3. The genotyping kit for polymorphic loci of a folate metabolism gene according to claim 1, wherein: the number of the heat insulation pads (303) is two, and the heat insulation pads are distributed symmetrically on the left and right sides of the central axis of the kit body (1).
4. The genotyping kit for polymorphic loci of a folate metabolism gene according to claim 1, wherein: the extraction assembly comprises a sampling tube (306) fixed on the lower surface of the installation block (302), a second electric push rod (307) is fixed on the inner bottom wall of the installation block (302), an output shaft of the second electric push rod (307) penetrates through the inner bottom wall of the installation block (302) and extends to the inside of the sampling tube (306), a connecting rod (308) is fixed, a push plate (309) is fixed at the bottom end of the connecting rod (308), and a sealing gasket (310) is fixed on the outer side of the push plate (309).
5. The genotyping kit for polymorphic loci of a folate metabolism gene according to claim 4, wherein: the outer diameter of the pushing plate (309) is equal to the inner diameter of the sealing gasket (310), and the outer diameter of the sealing gasket (310) is matched with the inner diameter of the sampling tube (306).
6. The genotyping kit for polymorphic loci of a folate metabolism gene according to claim 1, wherein: feeding mechanism (6) are including fixing the fixed block at mounting groove (5) left side inner wall, be fixed with slide bar (601) between the back of fixed block and the back inner wall of mounting groove (5), the outside sliding connection of slide bar (601) has connecting plate (602), the front of connecting plate (602) is fixed with places platform (603), the front of placing platform (603) is fixed with backup pad (604), the front of backup pad (604) is fixed with handle (605), the upper surface of placing platform (603) is fixed with places seat (606), the upper surface of placing platform (603) is fixed with detects platform (607).
7. The genotyping kit for polymorphic loci of a folate metabolism gene according to claim 6, wherein: the front of kit body (1) has seted up the opening, backup pad (604) are located the inside of opening, and the length and the width of backup pad (604) are with open-ended length and width looks adaptation respectively.
CN202322544072.XU 2023-09-19 2023-09-19 Genotype detection kit for polymorphic locus of folic acid metabolism gene Active CN220846120U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202322544072.XU CN220846120U (en) 2023-09-19 2023-09-19 Genotype detection kit for polymorphic locus of folic acid metabolism gene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202322544072.XU CN220846120U (en) 2023-09-19 2023-09-19 Genotype detection kit for polymorphic locus of folic acid metabolism gene

Publications (1)

Publication Number Publication Date
CN220846120U true CN220846120U (en) 2024-04-26

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CN (1) CN220846120U (en)

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