CN113532986B - Pick-and-place device capable of being used for sealing tissue slices - Google Patents
Pick-and-place device capable of being used for sealing tissue slices Download PDFInfo
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- CN113532986B CN113532986B CN202110758649.XA CN202110758649A CN113532986B CN 113532986 B CN113532986 B CN 113532986B CN 202110758649 A CN202110758649 A CN 202110758649A CN 113532986 B CN113532986 B CN 113532986B
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- stopper
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
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- Life Sciences & Earth Sciences (AREA)
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- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Microscoopes, Condenser (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses a pick-and-place device for sealing tissue slices, which comprises a sliding rail, a rotary rebound mechanism, a sealing slice pick-up mechanism and a driving mechanism, wherein the sliding rail is arranged on the sliding rail; slide rail: the front end of the device is connected with a sliding block in a sliding way, and the front side surface of the sliding block is provided with a mounting plate; a rotary rebound mechanism: the lower end of the left side of the mounting plate is provided with a plurality of grooves; a seal piece picking mechanism: the upper end of the front side surface of the rotary rebound mechanism is fixedly connected with the upper end of the front side surface of the rotary rebound mechanism through a bolt; wherein: still include fixed block and stopper, the fixed block is located the outside left side below of slide rail, and the stopper passes through bolt fixed connection in the leading flank lower extreme of fixed block, and the right side end of stopper corresponds with rotatory resilient mechanism's left side lower extreme position, and this can be used to the pick-and-place device that tissue slice sealed, can extrude the bubble at seal piece and slide glass laminating in-process, reduces the little bubble that slide seal cover in-process arouses.
Description
Technical Field
The invention relates to the technical field of medical equipment, in particular to a pick-and-place device for sealing tissue slices.
Background
The sealing sheet is characterized in that a tissue slice is sealed and stored between a glass slide and a cover glass, a small amount of sealing sheet glue is dripped to prevent the sealing sheet glue from contacting air, oxidation and fading of the sealing sheet are prevented, the sealing sheet glue is favorable for microscopic observation and storage, neutral gum is usually adopted as the sealing sheet glue, an automatic sealing sheet machine is already available in the market at present, when the sealing sheet machine is used, a xylene bottle is firstly checked, the dripping dispensing amount is checked, the available amount of the adhesive tape is checked, the length specification of the adhesive tape is selected, whether a splicing basket is installed in place is checked, a power supply is turned on during working, a filter screen switch is turned on, after the working is finished, the power supply is turned off, the machine is wiped, and most of sealing sheet picking and placing structures in the market are semi-arc-shaped devices controlled by one power, and a plurality of power systems are required to be used for running, and the energy consumption is high.
Disclosure of Invention
The invention aims to overcome the existing defects, and provides a pick-and-place device for sealing tissue slices, which can extrude bubbles in the process of bonding a sealing piece and a glass slide, reduce small bubbles caused in the process of sealing the glass slide, effectively solve the problems in the background art, reduce energy consumption and protect the environment.
In order to achieve the above purpose, the present invention provides the following technical solutions: a pick-and-place device for sealing tissue slices comprises a sliding rail, a rotary rebound mechanism and a sealing slice pick-up mechanism;
slide rail: the front end of the device is connected with a sliding block in a sliding way, and the front side surface of the sliding block is provided with a mounting plate;
a rotary rebound mechanism: the lower end of the left side of the mounting plate is provided with a plurality of grooves;
a seal piece picking mechanism: the upper end of the front side surface of the rotary rebound mechanism is fixedly connected with the upper end of the front side surface of the rotary rebound mechanism through a bolt;
wherein: still include fixed block and stopper, the fixed block is located the outside left side below of slide rail, and the stopper passes through bolt fixed connection in the leading flank lower extreme of fixed block, and the right side end of stopper corresponds with rotatory resilience mechanism's left side lower extreme position, and environmental protection and energy saving need not to consume extra power, reduces the energy consumption, can extrude the bubble at seal piece and slide glass laminating in-process, reduces the little bubble that slide glass closing cap in-process arouses, avoids the bubble to influence the tissue and observes down, makes things convenient for doctor's diagnosis.
Further, rotatory resilient mechanism includes rotor plate, rotation axis and spring, the rotor plate passes through the rotation axis and rotates to be connected in the left side lower extreme of mounting panel, and the spring sets up between the left side upper end of rotor plate and the left side slot of mounting panel, can make in seal piece and the slide glass laminating action go on according to certain order and direction to can extrude the venthole.
Further, rotatory resilience mechanism still includes the gyro wheel, the gyro wheel rotates and connects in the left side lower extreme of rotor plate, and the gyro wheel corresponds with the right side end position of stopper, reduces the frictional force between the inside part in the device operation in-process, guarantees that the device can steady operation.
Further, seal piece picking up mechanism includes mount pad, absorbs component and optical fiber sensor, the mount pad passes through bolt fixed connection in the leading flank left side of rotor plate, absorbs the component and sets up respectively in the installing port of seting up on the right side of mount pad upper surface, and optical fiber sensor sets up in the through-hole of seting up at the right side middle part of mount pad upper surface, and optical fiber sensor's output electricity connects the input of system control ware, and seal piece picking up mechanism is as the part of tissue section sealing system, receives the control of system control ware, can realize the operation of absorbing of seal piece.
Further, the suction component is formed by sucking disc, fixed mounting pole and manometer combination, and fixed mounting pole sets up in the installing port of seting up on mount pad upper surface right side, and the manometer sets up in the upper end of fixed mounting pole, and the sucking disc sets up in the bottom end department of fixed mounting pole respectively, and the position of three sucking disc increases from left to right in proper order, and the input of system control ware is connected to the output electricity of manometer, and the suction component is as the part of tissue slice sealing system, receives system control ware's control, can make the sealing piece have little bending after being inhaled, is difficult to cause the condition of many sealing pieces bonding.
Compared with the prior art, the invention has the beneficial effects that: the pick-and-place device for sealing tissue slices has the following advantages:
the sealing piece picking mechanism is driven to move by the rotary rebound mechanism, when the sealing piece picking mechanism moves downwards, the optical fiber sensor detects the sealing piece and transmits signals to the system controller, the system controller controls the motor to descend in a decelerating way until the sucker contacts with the sealing piece to generate vacuum, the pressure gauge detects the vacuum and transmits signals to the system controller, the system controller controls the motor to reversely rotate to drive the sealing piece picking mechanism to suck up the sealing piece, the external transmission part is waited to convey the glass slide to the lower part of the sealing piece picking mechanism, the system controller controls the motor to reversely rotate again to drive the sealing piece picking mechanism to move downwards, and in the process of downwards moving the sealing piece picking mechanism, because the position of three sucking disc increases in proper order from left to right, consequently the sealing piece of sucking disc below is left low right high incline condition, the left side of sealing piece contacts the slide glass of below first, simultaneously, the right side end and the gyro wheel contact of stopper, the gyro wheel is the left end of rotor plate upwards moving, spring compression, the right-hand member of rotor plate passes through the rotation axis and rotates downwards, and then the suction component through mount pad and top drives the sealing piece and carries out the laminating of sealing piece and slide glass from left to right with convex route, can extrude the bubble at sealing piece and slide glass laminating in-process, reduce the little bubble that the slide sealing cover in-process arouses, avoid the bubble to influence the tissue mirror observation, make things convenient for doctor's diagnosis.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is a schematic plan view of the present invention;
FIG. 3 is a schematic view of a rotary resilient mechanism according to the present invention;
fig. 4 is a schematic structural view of the suction member of the present invention.
In the figure: the device comprises a sliding rail 1, a sliding block 2, a mounting plate 3, a rotary rebound mechanism 4, a rotary plate 41, a rotary shaft 42, a roller 43, a spring 44, a sealing piece pickup mechanism 5, a mounting seat 51, a suction component 52, a suction disc 521, a fixed mounting rod 522, a pressure gauge 523, an optical fiber sensor 53, a fixed block 6 and a limiting block 7.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1-4, the present invention provides the following technical solutions:
embodiment one: a pick-and-place device for sealing tissue slices comprises a sliding rail 1, a rotary rebound mechanism 4 and a sealing slice pick-up mechanism 5;
slide rail 1: the sliding rail 1 provides guiding function for the operation of other components, the front end of the sliding rail is connected with the sliding block 2 in a sliding way, the sliding block 2 can drive the other components to slide along the sliding rail 1, the front side surface of the sliding block 2 is provided with the mounting plate 3, and the mounting plate 3 is convenient for the installation of the other components;
rotary rebound mechanism 4: the rotary rebound mechanism 4 can extrude bubbles in the process of attaching the sealing piece and the glass slide, and is arranged at the lower left end of the mounting plate 3;
a die pick-up mechanism 5: the seal piece picking mechanism 5 realizes automatic seal piece picking operation and is fixedly connected to the upper end of the front side surface of the rotary rebound mechanism 4 through bolts;
wherein: still include fixed block 6 and stopper 7, fixed block 6 is located the outside left side below of slide rail 1, and stopper 7 passes through bolt fixed connection in the leading flank lower extreme of fixed block 6, and stopper 7's right side end corresponds with rotatory resilient mechanism 4 left side lower extreme position.
Embodiment two:
the difference between this embodiment and the first embodiment is that:
in this embodiment, the rotary resilient mechanism 4 includes a rotary plate 41, a rotary shaft 42, and a spring 44, the rotary plate 41 is rotatably connected to the left lower end of the mounting plate 3 through the rotary shaft 42, the spring 44 is disposed between the left upper end of the rotary plate 41 and the left slot of the mounting plate 3, the rotary resilient mechanism 4 further includes a roller 43, the roller 43 is rotatably connected to the left lower end of the rotary plate 41, and the roller 43 corresponds to the right end position of the stopper 7.
Specifically, in the process of moving the seal piece picking mechanism 5 downwards, the positions of the three suction cups 521 are sequentially increased from left to right, so that the seal piece sucked by the lower side of the suction cups 521 is in a tilting state with the left low side and the right high side, the left side of the seal piece is firstly contacted with the slide glass below, meanwhile, the right end of the limiting block 7 is contacted with the roller 43, the roller 43 moves upwards against the left end of the rotating plate 41, the spring 44 compresses, the right end of the rotating plate 41 rotates downwards through the rotating shaft 42, and further the suction members 52 above and the mounting seat 51 drive the seal piece to be attached to the slide glass from left to right in a circular arc route, so that air bubbles can be extruded in the attaching process of the seal piece and the slide glass.
Embodiment III:
the difference between this embodiment and the first embodiment is that:
in this embodiment, the seal piece picking mechanism 5 includes a mounting seat 51, a suction member 52 and an optical fiber sensor 53, the mounting seat 51 is fixedly connected to the left side of the front side of the rotating plate 41 through bolts, the suction member 52 is respectively disposed in a mounting opening formed on the right side of the upper surface of the mounting seat 51, the optical fiber sensor 53 is disposed in a through hole formed in the middle of the right side of the upper surface of the mounting seat 51, the output end of the optical fiber sensor 53 is electrically connected with the input end of the system controller, the suction member 52 is formed by combining a suction cup 521, a fixed mounting rod 522 and a pressure gauge 523, the fixed mounting rod 522 is disposed in a mounting opening formed on the right side of the upper surface of the mounting seat 51, the pressure gauge 523 is disposed at the upper end of the fixed mounting rod 522, the suction cups 521 are respectively disposed at the bottom ends of the fixed mounting rod 522, the positions of the three suction cups 521 are sequentially increased from left to right, and the output end of the pressure gauge 523 is electrically connected with the input end of the system controller.
Specifically, the arrangement is such that the rotary rebound mechanism 4 drives the seal piece picking mechanism 5 to move, when the seal piece picking mechanism 5 moves downwards, the optical fiber sensor 53 detects the seal piece and transmits a signal to the system controller, the system controller controls the motor to decelerate until the sucker 521 contacts the seal piece to generate vacuum, the pressure gauge 523 detects the vacuum and transmits the signal to the system controller, the system controller controls the motor to reversely rotate to drive the seal piece picking mechanism 5 to suck up the seal piece, and waits for the external transmission component to convey the slide glass to the lower part of the seal piece picking mechanism 5, and the system controller controls the seal piece picking mechanism 5 to move downwards.
The invention provides a pick-and-place device for sealing tissue slices, which has the following working principle: when the sealing piece picking mechanism 5 is driven to move by the rotary rebound mechanism 4, the sealing piece picking mechanism 5 moves downwards, the optical fiber sensor 53 detects the sealing piece and transmits signals to the system controller, the system controller controls the motor to decelerate until the sucker 521 is contacted with the sealing piece to generate vacuum, the pressure gauge 523 detects the vacuum and transmits signals to the system controller, the system controller controls the motor to reversely drive the sealing piece picking mechanism 5 to suck the sealing piece upwards, the external transmission part is waited to convey the glass slide to the lower part of the sealing piece picking mechanism 5, the system controller controls the sealing piece picking mechanism 5 to move downwards, in the process of moving downwards the sealing piece picking mechanism 5, as the positions of the three suckers 521 are sequentially increased from left to right, the sealing piece sucked by the sucker 521 is in a left-low and-right-high inclined state, the left side of the sealing piece is firstly contacted with the lower glass slide, meanwhile, the right side end of the limiting block 7 is contacted with the roller 43, the left end of the roller 43 is pushed up against the rotary plate 41 to move upwards, the spring 44 is compressed, the right end of the rotary plate 42 rotates downwards through the rotary shaft 42, and then the mounting member 52 is driven by the upper side of the rotary plate to drive the rotary plate to move the circular arc-shaped glass slide to be attached to the sealing piece, and finally, the sealing piece can be attached to the sealing piece can be picked up by the sealing piece through the vacuum device, and the sealing piece can be controlled to be attached to the sealing piece.
It should be noted that, the pressure gauge 523 disclosed in the present embodiment may be a vacuum pressure gauge with a model Z-50ZT, and the optical fiber sensor 53 may be an optical fiber sensor with a model FM-E31V1.2P, and the system controller controls the pressure gauge 523 and the optical fiber sensor 53 to work by a method commonly used in the prior art.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (2)
1. The utility model provides a pick-and-place device that can be used to tissue slice seal which characterized in that: comprises a sliding rail (1), a rotary rebound mechanism (4) and a sealing piece picking mechanism (5);
slide rail (1): the front end of the device is connected with a sliding block (2) in a sliding way, and the front side surface of the sliding block (2) is provided with a mounting plate (3);
rotary rebound mechanism (4): the rotary rebound mechanism (4) comprises a rotary plate (41), a rotary shaft (42) and a spring (44), wherein the rotary plate (41) is rotationally connected to the left lower end of the mounting plate (3) through the rotary shaft (42), the spring (44) is arranged between the left upper end of the rotary plate (41) and a left slot of the mounting plate (3), the rotary rebound mechanism (4) further comprises a roller (43), the roller (43) is rotationally connected to the left lower end of the rotary plate (41), and the roller (43) corresponds to the right end position of the limiting block (7);
a seal piece picking mechanism (5): the sealing piece picking mechanism (5) comprises a mounting seat (51), a suction component (52) and an optical fiber sensor (53), wherein the mounting seat (51) is fixedly connected to the left side of the front side of the rotating plate (41) through bolts, the suction component (52) is respectively arranged in mounting openings formed in the right side of the upper surface of the mounting seat (51), the optical fiber sensor (53) is arranged in a through hole formed in the middle of the right side of the upper surface of the mounting seat (51), and the output end of the optical fiber sensor (53) is electrically connected with a system controller;
wherein: still include fixed block (6) and stopper (7), fixed block (6) are located the outside left side below of slide rail (1), and stopper (7) are through bolt fixed connection in the leading flank lower extreme of fixed block (6), and the right side end of stopper (7) corresponds with rotatory resilience mechanism (4) left side lower extreme position.
2. A pick-and-place device for sealing tissue slices as claimed in claim 1, wherein: the suction component (52) is formed by combining a sucker (521), a fixed mounting rod (522) and a pressure gauge (523), the fixed mounting rod (522) is arranged in a mounting port formed in the right side of the upper surface of the mounting seat (51), the pressure gauge (523) is arranged at the upper end of the fixed mounting rod (522), the sucker (521) is respectively arranged at the bottom end of the fixed mounting rod (522), the positions of the three suckers (521) are sequentially increased from left to right, and the output end of the pressure gauge (523) is electrically connected with the system controller.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110758649.XA CN113532986B (en) | 2021-07-05 | 2021-07-05 | Pick-and-place device capable of being used for sealing tissue slices |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110758649.XA CN113532986B (en) | 2021-07-05 | 2021-07-05 | Pick-and-place device capable of being used for sealing tissue slices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113532986A CN113532986A (en) | 2021-10-22 |
| CN113532986B true CN113532986B (en) | 2023-09-12 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110758649.XA Active CN113532986B (en) | 2021-07-05 | 2021-07-05 | Pick-and-place device capable of being used for sealing tissue slices |
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| CN (1) | CN113532986B (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997026541A1 (en) * | 1996-01-17 | 1997-07-24 | Australian Biomedical Corporation Ltd. | Specimen preparation |
| WO2003091137A2 (en) * | 2002-04-26 | 2003-11-06 | Ventana Medical Systems, Inc. | Method and apparatus for automated coverslipping |
| CN109490044A (en) * | 2018-12-25 | 2019-03-19 | 宁波察微生物科技有限公司 | A kind of mounting machine |
| CN111650016A (en) * | 2020-05-29 | 2020-09-11 | 贵州金域医学检验中心有限公司 | Tissue slice mounting system |
| CN112485081A (en) * | 2020-11-17 | 2021-03-12 | 福州艾迪康医学检验所有限公司 | Slide glass mounting device and slide glass mounting method |
| CN112763299A (en) * | 2020-12-21 | 2021-05-07 | 广东金泉医疗科技有限公司 | Cover glass sucking and pressing mounting device and automatic mounting equipment |
| CN112781948A (en) * | 2020-12-21 | 2021-05-11 | 广东金泉医疗科技有限公司 | Cover glass absorbs and transfers mounting device and automatic mounting equipment |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10724929B2 (en) * | 2016-05-13 | 2020-07-28 | Clarapath, Inc. | Automated tissue sectioning and storage system |
-
2021
- 2021-07-05 CN CN202110758649.XA patent/CN113532986B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997026541A1 (en) * | 1996-01-17 | 1997-07-24 | Australian Biomedical Corporation Ltd. | Specimen preparation |
| WO2003091137A2 (en) * | 2002-04-26 | 2003-11-06 | Ventana Medical Systems, Inc. | Method and apparatus for automated coverslipping |
| CN109490044A (en) * | 2018-12-25 | 2019-03-19 | 宁波察微生物科技有限公司 | A kind of mounting machine |
| CN111650016A (en) * | 2020-05-29 | 2020-09-11 | 贵州金域医学检验中心有限公司 | Tissue slice mounting system |
| CN112485081A (en) * | 2020-11-17 | 2021-03-12 | 福州艾迪康医学检验所有限公司 | Slide glass mounting device and slide glass mounting method |
| CN112763299A (en) * | 2020-12-21 | 2021-05-07 | 广东金泉医疗科技有限公司 | Cover glass sucking and pressing mounting device and automatic mounting equipment |
| CN112781948A (en) * | 2020-12-21 | 2021-05-11 | 广东金泉医疗科技有限公司 | Cover glass absorbs and transfers mounting device and automatic mounting equipment |
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| CN113532986A (en) | 2021-10-22 |
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