CN113532986A - Pick-and-place device for tissue slice sealing - Google Patents

Pick-and-place device for tissue slice sealing Download PDF

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Publication number
CN113532986A
CN113532986A CN202110758649.XA CN202110758649A CN113532986A CN 113532986 A CN113532986 A CN 113532986A CN 202110758649 A CN202110758649 A CN 202110758649A CN 113532986 A CN113532986 A CN 113532986A
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China
Prior art keywords
mounting
pick
slide rail
tissue slice
stopper
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CN202110758649.XA
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CN113532986B (en
Inventor
侯景辉
匡亚玲
黄华东
廖世贤
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Guangzhou Naique Medical Appliances Co ltd
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Guangzhou Naique Medical Appliances Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813Producing thin layers of samples on a substrate, e.g. smearing, spinning-on

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

The invention discloses a pick-and-place device for tissue slice sealing, which comprises a slide rail, a rotary rebounding mechanism, a sealing piece picking mechanism and a driving mechanism, wherein the slide rail is provided with a slide rail; a slide rail: the front end of the sliding block is connected with a sliding block in a sliding way, and the front side surface of the sliding block is provided with a mounting plate; rotating the rebound mechanism: the lower end of the left side of the mounting plate is provided with a groove; the mounting picking mechanism: the upper end of the front side surface of the rotary rebounding mechanism is fixedly connected with the upper end of the front side surface of the rotary rebounding mechanism through a bolt; wherein: still include fixed block and stopper, the fixed block is located the outside left side below of slide rail, and the stopper passes through bolt fixed connection in the leading flank lower extreme of fixed block, and the right side end of stopper corresponds with the left side lower extreme position of rotatory resilience mechanism, and this pick-and-place device that can be used to tissue slice sealing can extrude out the bubble at mounting and slide glass laminating in-process, reduces the microbubble that slide capping in-process arouses.

Description

Pick-and-place device for tissue slice sealing
Technical Field
The invention relates to the technical field of medical equipment, in particular to a picking and placing device for tissue slice sealing.
Background
The mounting is to mount and preserve the tissue slice between the glass slide and the cover glass, drip a small amount of mounting glue, make it not contact with air, prevent its oxidation, fade, help the microscopic examination observe and preserve, the mounting glue usually adopts neutral gum, there is automatic mounting machine on the market at present, while using the mounting machine, check the xylene bottle at first, checking the dispensing amount of the dropping liquid, checking the usable amount of the adhesive tape, selecting the length specification of the adhesive tape, checking whether the splicing basket is installed in place or not, switching on a power supply and a filter screen switch during working, switching off the power supply after the working is finished, wiping the machine, most of the sealing piece picking and placing structures on the market are a semi-arc device controlled by power, the semi-arc device is slowly placed from one end to the other end, a plurality of power systems are needed for operation, and energy consumption is high.
Disclosure of Invention
The invention aims to overcome the defects in the prior art, and provides a pick-and-place device for tissue slice sealing, which can extrude air bubbles in the process of laminating a sealing sheet and a glass slide, reduce small bubbles caused in the process of sealing and covering the glass slide, effectively solve the problems in the background art, reduce energy consumption and protect the environment.
In order to achieve the purpose, the invention provides the following technical scheme: a pick-and-place device for tissue slice sealing comprises a slide rail, a rotary rebounding mechanism and a sealing piece picking mechanism;
a slide rail: the front end of the sliding block is connected with a sliding block in a sliding way, and the front side surface of the sliding block is provided with a mounting plate;
rotating the rebound mechanism: the lower end of the left side of the mounting plate is provided with a groove;
the mounting picking mechanism: the upper end of the front side surface of the rotary rebounding mechanism is fixedly connected with the upper end of the front side surface of the rotary rebounding mechanism through a bolt;
wherein: still include fixed block and stopper, the fixed block is located the outside left side below of slide rail, and the stopper passes through bolt fixed connection in the leading flank lower extreme of fixed block, and the right side end of stopper corresponds with the left side lower extreme position of rotatory resilience mechanism, and environmental protection and energy saving need not to consume extra power, reduces the energy resource consumption, can extrude out the bubble at mounting and slide glass laminating in-process, reduces the small bubble that the slide capping in-process arouses, avoids the bubble to influence the lower mirror of tissue and observes, makes things convenient for doctor's diagnosis.
Further, rotatory resilience mechanism includes rotor plate, rotation axis and spring, the rotor plate passes through the rotation axis and rotates to be connected in the left side lower extreme of mounting panel, and the spring sets up between the left side upper end of rotor plate and the left side notch of mounting panel, can make in mounting and slide glass laminating action go on according to certain order and direction to can extrude out the bubble.
Further, rotatory resilience mechanism still includes the gyro wheel, the gyro wheel rotates to be connected in the left side lower extreme of rotor plate, and the gyro wheel corresponds with the right side end position of stopper, reduces the frictional force between the internals in the device operation process, guarantees that the device can even running.
Further, the mounting seat is fixedly connected to the left side of the front side face of the rotating plate through bolts, the absorbing members are respectively arranged in mounting ports formed in the right side of the upper surface of the mounting seat, the optical fiber sensor is arranged in a through hole formed in the middle of the right side of the upper surface of the mounting seat, the output end of the optical fiber sensor is electrically connected with the input end of the system controller, and the mounting piece picking mechanism serves as one part of a tissue slice sealing system and is controlled by the system controller, so that the absorbing operation of the mounting piece can be realized.
Further, it is formed by sucking disc, fixed mounting pole and manometer combination to absorb the component, the fixed mounting pole sets up in the mount pad upper surface right side installation mouth of seting up, the manometer sets up in the upper end of fixed mounting pole, the sucking disc sets up respectively in the bottom end department of fixed mounting pole, the position of three sucking disc from left to right increases in proper order, the input of the output electric connection system controller of manometer, absorb the component as a part of tissue slice sealing system, receive system controller's control, can make the mounting have little bending after being inhaled, be difficult to cause the adhesive condition of many mountings.
Compared with the prior art, the invention has the beneficial effects that: this can be used for pick-and-place device that tissue slice sealed has following benefit:
the rotary rebounding mechanism drives the sealing sheet picking mechanism to move, when the sealing sheet picking mechanism moves downwards, the optical fiber sensor detects a sealing sheet and transmits a signal to the system controller, the system controller controls the motor to slow down and descend until the sucking discs are contacted with the sealing sheet to generate vacuum, the pressure gauge detects vacuum and transmits the signal to the system controller, the system controller controls the motor to reversely rotate to drive the sealing sheet picking mechanism to suck the sealing sheet upwards, an external transmission part is waited to convey a glass slide to the lower part of the sealing sheet picking mechanism, the system controller controls the motor to reversely rotate again to drive the sealing sheet picking mechanism to move downwards, and in the process of downward movement of the sealing sheet picking mechanism, the positions of the three sucking discs are sequentially increased from left to right, so that the sealing sheet sucked under the sucking discs is in an inclined state with a lower left and a higher right, the left side of the sealing sheet is firstly contacted with the glass slide under the sucking disc, and meanwhile, the right end head of the limiting block is contacted with the roller, the left end that the roller was supporting the rotor plate moves up, the spring compression, the right-hand member of rotor plate passes through the rotation axis and rotates downwards, and then drives the mounting pad through the absorption component of mount pad and top and turns right from a left side with convex route and carry out the laminating of mounting pad and slide glass, can extrude the bubble at mounting pad and slide glass laminating in-process, reduces the little bubble that the slide capping in-process arouses, avoids the bubble to influence the observation of organizing the lower mirror, makes things convenient for doctor's diagnosis.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic plan view of the present invention;
FIG. 3 is a schematic structural view of a rotary rebounding mechanism of the present invention;
fig. 4 is a schematic structural view of the sucking member of the present invention.
In the figure: the device comprises a sliding rail 1, a sliding block 2, a mounting plate 3, a rotary rebounding mechanism 4, a rotary plate 41, a rotary shaft 42, a roller 43, a spring 44, a sealing piece 5 picking mechanism, a mounting seat 51, a sucking component 52, a suction cup 521, a fixed mounting rod 522, a pressure gauge 523, an optical fiber sensor 53, a fixed block 6 and a limiting block 7.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-4, the present invention provides the following technical solutions:
the first embodiment is as follows: a pick-and-place device for tissue slice sealing comprises a slide rail 1, a rotary rebounding mechanism 4 and a sealing piece picking mechanism 5;
slide rail 1: the slide rail 1 provides a guiding function for the operation of other parts, the front end of the slide rail is connected with a slide block 2 in a sliding way, the slide block 2 can drive the other parts to slide along the slide rail 1, the front side surface of the slide block 2 is provided with a mounting plate 3, and the mounting plate 3 is convenient for the mounting of the other parts;
rotating the rebound mechanism 4: the rotary rebounding mechanism 4 can enable bubbles to be extruded in the process of attaching the mounting plate and the glass slide and is arranged at the lower end of the left side of the mounting plate 3;
the seal piece picking mechanism 5: the sealing piece picking mechanism 5 realizes the automatic picking operation of the sealing piece and is fixedly connected to the upper end of the front side surface of the rotary rebounding mechanism 4 through a bolt;
wherein: still include fixed block 6 and stopper 7, fixed block 6 is located the outside left side below of slide rail 1, and stopper 7 passes through bolt fixed connection in the leading flank lower extreme of fixed block 6, and the right side end of stopper 7 corresponds with the left side lower extreme position of rotatory resilient means 4.
Example two:
the difference between this embodiment and the first embodiment is:
in this embodiment, rotatory resilient mechanism 4 includes rotor plate 41, rotation axis 42 and spring 44, and rotor plate 41 rotates through rotation axis 42 and connects in the left side lower extreme of mounting panel 3, and spring 44 sets up between the left side notch of the left side upper end of rotor plate 41 and mounting panel 3, and rotatory resilient mechanism 4 still includes gyro wheel 43, and gyro wheel 43 rotates and connects in the left side lower extreme of rotor plate 41, and gyro wheel 43 corresponds with the right side end position of stopper 7.
Specifically, set up like this, in the in-process that the mounting piece picks up mechanism 5 and moves down, because the position of three sucking disc 521 increases from left to right in proper order, therefore the mounting piece that the sucking disc 521 below was absorb is the low inclined state of right side height, the slide glass of below is contacted first in the left side of mounting piece, and simultaneously, the right side end and the gyro wheel 43 contact of stopper 7, gyro wheel 43 pushes up the left end rebound of rotor plate 41, the compression of spring 44, the right-hand member of rotor plate 41 passes through rotation axis 42 and rotates downwards, and then the absorption component 52 through mount pad 51 and top drives the mounting piece and carries out the laminating of mounting piece and slide glass with convex route from left to right, make the mounting piece and slide glass laminating in-process can extrude bubble.
Example three:
the difference between this embodiment and the first embodiment is:
in this embodiment, the mounting base 51 is fixedly connected to the left side of the front side of the rotating plate 41 by bolts, the sucking members 52 are respectively disposed in the mounting openings formed on the right side of the upper surface of the mounting base 51, the optical fiber sensor 53 is disposed in the through hole formed in the middle of the right side of the upper surface of the mounting base 51, the output end of the optical fiber sensor 53 is electrically connected to the input end of the system controller, the sucking member 52 is composed of a sucking disc 521, the fixed mounting pole 522 and the manometer 523 make up and form, and the fixed mounting pole 522 sets up in the installation hole that the upper surface right side was seted up of mount pad 51, and manometer 523 sets up in the upper end of fixed mounting pole 522, and sucking disc 521 sets up respectively in the bottom end department of fixed mounting pole 522, and the position of three sucking disc 521 increases from left to right in proper order, and the input of the output electricity connection system controller of manometer 523.
Specifically, set up like this, it picks up mechanism 5 and removes to drive the mounting through rotatory resilient means 4, mounting picks up mechanism 5 and down when moving, optical fiber sensor 53 detects the mounting, signal transmission is for system controller, system controller control motor slows down and descends, until sucking disc 521 and mounting contact production vacuum, manometer 523 detects the vacuum, signal transmission is for system controller, system controller control motor reversal drives mounting and picks up mechanism 5 and up the mounting, wait for outside transmission part to carry the below that mounting picked up mechanism 5 to the slide, system controller control mounting picks up mechanism 5 and down.
The working principle of the pick-and-place device for tissue slice sealing provided by the invention is as follows: the rotary rebounding mechanism 4 drives the sealing sheet picking mechanism 5 to move, when the sealing sheet picking mechanism 5 moves downwards, the optical fiber sensor 53 detects a sealing sheet and transmits a signal to the system controller, the system controller controls the motor to slow down and descend until the sucker 521 is in contact with the sealing sheet to generate vacuum, the pressure gauge 523 detects vacuum and transmits the signal to the system controller, the system controller controls the motor to reversely rotate to drive the sealing sheet picking mechanism 5 to suck the sealing sheet upwards, an external transmission part is waited to convey the glass sheet to the lower part of the sealing sheet picking mechanism 5, the system controller controls the sealing sheet picking mechanism 5 to move downwards, and in the process that the sealing sheet picking mechanism 5 moves downwards, as the positions of the three suckers 521 are sequentially increased from left to right, the sealing sheet sucked under the sucker 521 is in an inclined state of low left and high right, the left side of the sealing sheet is firstly contacted with the glass sheet under the left side, meanwhile, the right end of the limiting block 7 is in contact with the roller 43, the roller 43 pushes against the left end of the rotating plate 41 to move upwards, the spring 44 is compressed, the right end of the rotating plate 41 rotates downwards through the rotating shaft 42, and then the mounting seat 51 and the sucking member 52 above the mounting seat drive the mounting piece to be attached to the glass slide from left to right in a circular arc-shaped path, so that bubbles can be extruded in the process of attaching the mounting piece to the glass slide, finally the sucking disc breaks vacuum, and the system controller drives the mounting piece picking device to move upwards, so that one-time mounting piece picking is completed.
It should be noted that the pressure gauge 523 disclosed in this embodiment may be a vacuum pressure gauge of Z-50ZT, the optical fiber sensor 53 may be an optical fiber sensor of FM-E31V1.2P, and the system controller controls the pressure gauge 523 and the optical fiber sensor 53 to operate by a method commonly used in the prior art.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1. A pick and place device for tissue slice sealing is characterized in that: comprises a slide rail (1), a rotary rebounding mechanism (4) and a mounting pick-up mechanism (5);
slide rail (1): the front end of the sliding block is connected with a sliding block (2) in a sliding way, and the front side surface of the sliding block (2) is provided with a mounting plate (3);
rotation rebound mechanism (4): is arranged at the lower end of the left side of the mounting plate (3);
a seal piece picking mechanism (5): is fixedly connected to the upper end of the front side surface of the rotary rebounding mechanism (4) through a bolt;
wherein: still include fixed block (6) and stopper (7), fixed block (6) are located the outside left side below of slide rail (1), and stopper (7) pass through bolt fixed connection in the leading flank lower extreme of fixed block (6), and the right side end of stopper 7 corresponds with the left side lower extreme position of rotatory resilience mechanism (4).
2. A pick and place apparatus for tissue slice mounting as claimed in claim 1, wherein: rotatory resilient means (4) include rotor plate (41), rotation axis (42) and spring (44), rotor plate (41) rotate through rotation axis (42) and connect in the left side lower extreme of mounting panel (3), and spring (44) set up between the left side notch of the left side upper end of rotor plate (41) and mounting panel (3).
3. A pick and place apparatus for tissue slice mounting as claimed in claim 2, wherein: rotatory resilient mounting (4) still include gyro wheel (43), gyro wheel (43) rotate to be connected in the left side lower extreme of rotor plate (41), and gyro wheel (43) correspond with the right side end position of stopper 7.
4. A pick and place apparatus for tissue slice mounting as claimed in claim 2, wherein: the mounting seat (51) is fixedly connected to the left side of the front side face of the rotating plate (41) through bolts, the absorbing member (52) is arranged in a mounting hole formed in the right side of the upper surface of the mounting seat (51) respectively, the optical fiber sensor (53) is arranged in a through hole formed in the middle of the right side of the upper surface of the mounting seat (51), and the output end of the optical fiber sensor (53) is electrically connected with a system controller.
5. A pick and place apparatus for tissue slice mounting as claimed in claim 4, wherein: the sucking component (52) is formed by combining a sucker (521), a fixed mounting rod (522) and a pressure gauge (523), the fixed mounting rod (522) is arranged in a mounting hole formed in the right side of the upper surface of the mounting seat (51), the pressure gauge (523) is arranged at the upper end of the fixed mounting rod (522), the suckers (521) are respectively arranged at the bottom end of the fixed mounting rod (522), the positions of the three suckers (521) are sequentially increased from left to right, and the output end of the pressure gauge (523) is electrically connected with a system controller.
CN202110758649.XA 2021-07-05 2021-07-05 Pick-and-place device capable of being used for sealing tissue slices Active CN113532986B (en)

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CN202110758649.XA CN113532986B (en) 2021-07-05 2021-07-05 Pick-and-place device capable of being used for sealing tissue slices

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Application Number Priority Date Filing Date Title
CN202110758649.XA CN113532986B (en) 2021-07-05 2021-07-05 Pick-and-place device capable of being used for sealing tissue slices

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CN113532986B CN113532986B (en) 2023-09-12

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026541A1 (en) * 1996-01-17 1997-07-24 Australian Biomedical Corporation Ltd. Specimen preparation
WO2003091137A2 (en) * 2002-04-26 2003-11-06 Ventana Medical Systems, Inc. Method and apparatus for automated coverslipping
US20170328818A1 (en) * 2016-05-13 2017-11-16 Clarapath, Inc. Automated tissue sectioning and storage system
CN109490044A (en) * 2018-12-25 2019-03-19 宁波察微生物科技有限公司 A kind of mounting machine
CN111650016A (en) * 2020-05-29 2020-09-11 贵州金域医学检验中心有限公司 Tissue slice mounting system
CN112485081A (en) * 2020-11-17 2021-03-12 福州艾迪康医学检验所有限公司 Slide glass mounting device and slide glass mounting method
CN112763299A (en) * 2020-12-21 2021-05-07 广东金泉医疗科技有限公司 Cover glass sucking and pressing mounting device and automatic mounting equipment
CN112781948A (en) * 2020-12-21 2021-05-11 广东金泉医疗科技有限公司 Cover glass absorbs and transfers mounting device and automatic mounting equipment

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997026541A1 (en) * 1996-01-17 1997-07-24 Australian Biomedical Corporation Ltd. Specimen preparation
WO2003091137A2 (en) * 2002-04-26 2003-11-06 Ventana Medical Systems, Inc. Method and apparatus for automated coverslipping
US20170328818A1 (en) * 2016-05-13 2017-11-16 Clarapath, Inc. Automated tissue sectioning and storage system
CN109490044A (en) * 2018-12-25 2019-03-19 宁波察微生物科技有限公司 A kind of mounting machine
CN111650016A (en) * 2020-05-29 2020-09-11 贵州金域医学检验中心有限公司 Tissue slice mounting system
CN112485081A (en) * 2020-11-17 2021-03-12 福州艾迪康医学检验所有限公司 Slide glass mounting device and slide glass mounting method
CN112763299A (en) * 2020-12-21 2021-05-07 广东金泉医疗科技有限公司 Cover glass sucking and pressing mounting device and automatic mounting equipment
CN112781948A (en) * 2020-12-21 2021-05-11 广东金泉医疗科技有限公司 Cover glass absorbs and transfers mounting device and automatic mounting equipment

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