CN113509435A - Formula for nursing cow nipples and production method thereof - Google Patents
Formula for nursing cow nipples and production method thereof Download PDFInfo
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- CN113509435A CN113509435A CN202110834652.5A CN202110834652A CN113509435A CN 113509435 A CN113509435 A CN 113509435A CN 202110834652 A CN202110834652 A CN 202110834652A CN 113509435 A CN113509435 A CN 113509435A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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Abstract
The invention belongs to the technical field of cow nipple nursing, in particular to a formula for cow nipple nursing and a production method thereof, wherein the formula is prepared from the following raw materials in parts by mass: 1583.24-1599.16 parts of purified water, 1294-1306 parts of propylene glycol, 1294-1306 parts of glycerol, 202-214 parts of N-120, 202-214 parts of propanol, 56.91-57.49 parts of Emory658, 5.17-5.23 parts of Wintergree, 5.17-5.23 parts of Liquid Blue and the balance of purified water; add propylene glycol in the raw materials, adopt propylene glycol to play the effect of moisturizing, softening as organic solvent, can keep the moist of face cow nipple for a long time, effectually avoid cow nipple to dry and split, play the effect of the first intensive care of cow's milk, and have good bactericidal action, can form the free hydroxyl group of hydrophilic bond with the purifying water in the membrane and reduce, the water content of system reduces, thereby impel the chitosan cross-linking, form compact chitosan membrane on cow nipple surface, make cow nipple disinfectant play long-acting antibacterial property.
Description
Technical Field
The invention belongs to the technical field of cow nipple care, and particularly relates to a formula for cow nipple care and a production method thereof.
Background
Cow mastitis is a diverse inflammation of its mammary tissues, including occult mastitis and clinical mastitis. The disease is a frequently-occurring disease and frequently-occurring disease of dairy cows, about one third of the dairy cows all over the world are reported to have various types of mastitis, particularly, the incidence rate of the mastitis of the dairy cows is higher under the conditions of high temperature and high humidity in the south, and the incidence rate can reach more than 70% in rainy season. Mastitis can cause the reduction of milk yield, the reduction of the quality of fresh milk and the increase of replacement cost of cow herds, and is one of the most serious diseases causing the economic loss of cow production. The pathogenic microorganisms causing the mastitis are mostly caused by staphylococcus, streptococcus, escherichia coli and the like, the pathogenic microorganisms are mainly present on the body surface and in the environment of the dairy cow, and the pathogenic microorganisms polluted on the surface of the dairy cow breast can infect the breast through a milking machine, the hands of a milking person or towels for scrubbing the breast and the like, so that recessive mastitis or clinical mastitis is caused.
Causes a plurality of mastitis factors, such as mechanical injury of breasts, sudden change of negative pressure of a milking machine and the like, and causes the infection of mammary tissue with pathogenic bacteria, and the pathogenic bacteria can reach more than 150. There are many methods for preventing and treating cow mastitis, including antibiotic therapy, Chinese herbal medicine therapy, Chinese and western medicine combination therapy, vaccine immunity control and surgery therapy, immunopotentiator, etc. However, the most effective method for the prevention of mastitis in dairy cows is a comprehensive preventive measure, and among them, a teat dipping is one of the most commonly used methods.
Therefore, the technical field provides a formula for nursing cow nipples and a production method thereof, so as to solve the problems in the background.
Disclosure of Invention
To solve the problems set forth in the background art described above. The invention provides a formula for nursing cow nipples and a production method thereof, and the formula has the characteristics of simple and reasonable structure, convenience in use, simplicity in operation and high efficiency.
In order to achieve the purpose, the invention provides the following technical scheme: the formula for nursing the cow nipples is prepared from the following raw materials in parts by mass: 1583.24-1599.16 parts of purified water, 1294-1306 parts of propylene glycol, 1294-1306 parts of glycerol, 202-214 parts of N-120, 202-214 parts of propanol, 56.91-57.49 parts of Emory658, 5.17-5.23 parts of Wintergree, 5.17-5.23 parts of Liquid Blue and the balance of purified water.
Preferably, the material is prepared from the following raw materials in percentage by weight: 30.6% of purified water, 25% of propylene glycol, 25% of glycerol, N-1204%, 4% of propanol, 81.1% of Emory651%, 0.1% of Wintergreene, 0.1% of Liquid blue and the balance of purified water.
Preferably, the purified water can be water purifying agent.
The production method of the cow nipple care formula comprises the following steps:
s1, check before work:
s1.1, wearing protective equipment before operation;
s1.2, checking a field and equipment;
s1.3, when liquid materials are added, a weight reduction method is used to ensure the accuracy of the added weight;
s2, before feeding, sampling and detecting the electric conductivity of the purified water and the temperature of the purified water;
s3, putting the materials into a mixing tank to be weighed strictly according to the formula sequence and the proportion and the dosage;
s4, starting stirring for 20-25 min;
s5, sampling and detecting after stirring;
s6, after the detection is qualified, production and filling are started;
s7, packaging the finished product after filling;
s8, sticking a label;
and S9, packaging, and sampling and weighing.
Preferably, the hat, the safety glasses, the gas mask, the safety gloves, the acid and alkali resistant work clothes and the acid and alkali resistant leather boots are worn before the operation in the step S1.1.
Preferably, step S1.2 comprises the steps of: confirm that the production place is clean, the raise dust is probably not had, confirm that blending tank, feeding pipe use the clean water thoroughly to wash, whether reinforced pump need the sanitization and the inspection normal operation, whether inspection equipment pipeline, air pipe are normal, whether the used material of inspection is complete.
Preferably, the standards for purified water conductivity in step S2 are < 30. mu.s/cm, and the temperature of the purified water is < 25 ℃.
Preferably, the weight part of the finished product detected by sampling in step S5 is 300 ml.
Preferably, the product package in step S7 is divided into two sizes, 20ml and 2001.
Preferably, the rules of sampling and weighing in step S9 are as follows: and (4) carrying out spot check to confirm the weight of the first five barrels, and weighing according to 20% spot check in the process after the weight is stable.
Compared with the prior art, the invention has the beneficial effects that: the milk cow nipple nursing liquid has the advantages that the propylene glycol is added into the raw materials and is used as an organic solvent to achieve the effects of moisturizing and softening, the wetness of the cow nipple on the face can be kept for a long time, the cow nipple is effectively prevented from being dried and cracked, and the effect of powerfully nursing the cow's milk head is achieved.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the principles of the invention and not to limit the invention. In the drawings:
FIG. 1 is a schematic diagram of the ratio of parts of raw materials in the present invention;
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
Referring to fig. 1, the present invention provides the following technical solutions: the formula for nursing the cow nipples is prepared from the following raw materials in parts by mass: 1583.24 parts of purified water, 1294 parts of propylene glycol, 1294 parts of ganshan, 202 parts of N-120, 214 parts of propanol, 57.49 parts of Emory658, 5.23 parts of Wintergreee, 5.23 parts of Liquid Blue and the balance of purified water.
Specifically, the material is prepared from the following raw materials in percentage by weight: 30.6% of purified water, 25% of propylene glycol, 25% of glycerol, N-1204%, 4% of propanol, 81.1% of Emory651%, 0.1% of Wintergreene, 0.1% of Liquid blue and the balance of purified water.
Specifically, the purified water can be water purifying agent.
The production method of the cow nipple care formula comprises the following steps:
s1, check before work:
s1.1, wearing protective equipment before operation;
s1.2, checking a field and equipment;
s1.3, when liquid materials are added, a weight reduction method is used to ensure the accuracy of the added weight;
s2, before feeding, sampling and detecting the electric conductivity of the purified water and the temperature of the purified water;
s3, putting the materials into a mixing tank to be weighed strictly according to the formula sequence and the proportion and the dosage;
s4, starting stirring for 25 min;
s5, sampling and detecting after stirring;
s6, after the detection is qualified, production and filling are started;
s7, packaging the finished product after filling;
s8, sticking a label;
and S9, packaging, and sampling and weighing.
Specifically, in step S1.1, the user wears a hat, safety glasses, a gas mask, safety gloves, acid and alkali resistant work clothes and acid and alkali resistant leather boots before performing the operation.
Specifically, step S1.2 includes the following steps: confirm that the production place is clean, the raise dust is probably not had, confirm that blending tank, feeding pipe use the clean water thoroughly to wash, whether reinforced pump need the sanitization and the inspection normal operation, whether inspection equipment pipeline, air pipe are normal, whether the used material of inspection is complete.
Specifically, the standard of the purified water conductivity in step S2 is < 30. mu.s/cm, and the temperature of the purified water is < 25 ℃.
Specifically, the weight part of the finished product detected by sampling in step S5 is 300 ml.
Specifically, the product package in step S7 is divided into two specifications, 20ml and 2001.
Specifically, the sampling and weighing rule in step S9 is as follows: and (4) carrying out spot check to confirm the weight of the first five barrels, and weighing according to 20% spot check in the process after the weight is stable.
Example 2
Referring to fig. 1, the present invention provides the following technical solutions: the formula for nursing the cow nipples is prepared from the following raw materials in parts by mass: 1583.24 parts of purified water, 1294 parts of propylene glycol, 1294 parts of ganshan, 202 parts of N-120, 202 parts of propyl alcohol, 56.91 parts of Emory658, 5.17 parts of Wintergreee, 5.17 parts of Liquid Blue and the balance of purified water.
Specifically, the material is prepared from the following raw materials in percentage by weight: 30.6% of purified water, 25% of propylene glycol, 25% of glycerol, N-1204%, 4% of propanol, 81.1% of Emory651%, 0.1% of Wintergreene, 0.1% of Liquid blue and the balance of purified water.
Specifically, the purified water can be water purifying agent.
The production method of the cow nipple care formula comprises the following steps:
s1, check before work:
s1.1, wearing protective equipment before operation;
s1.2, checking a field and equipment;
s1.3, when liquid materials are added, a weight reduction method is used to ensure the accuracy of the added weight;
s2, before feeding, sampling and detecting the electric conductivity of the purified water and the temperature of the purified water;
s3, putting the materials into a mixing tank to be weighed strictly according to the formula sequence and the proportion and the dosage;
s4, starting stirring for 20 min;
s5, sampling and detecting after stirring;
s6, after the detection is qualified, production and filling are started;
s7, packaging the finished product after filling;
s8, sticking a label;
and S9, packaging, and sampling and weighing.
Specifically, in step S1.1, the user wears a hat, safety glasses, a gas mask, safety gloves, acid and alkali resistant work clothes and acid and alkali resistant leather boots before performing the operation.
Specifically, step S1.2 includes the following steps: confirm that the production place is clean, the raise dust is probably not had, confirm that blending tank, feeding pipe use the clean water thoroughly to wash, whether reinforced pump need the sanitization and the inspection normal operation, whether inspection equipment pipeline, air pipe are normal, whether the used material of inspection is complete.
Specifically, the standard of the purified water conductivity in step S2 is < 30. mu.s/cm, and the temperature of the purified water is < 25 ℃.
Specifically, the weight part of the finished product detected by sampling in step S5 is 300 ml.
Specifically, the product package in step S7 is divided into two specifications, 20ml and 2001.
Specifically, the sampling and weighing rule in step S9 is as follows: and (4) carrying out spot check to confirm the weight of the first five barrels, and weighing according to 20% spot check in the process after the weight is stable.
Example 3
Referring to fig. 1, the present invention provides the following technical solutions: the formula for nursing the cow nipples is prepared from the following raw materials in parts by mass: 1591.2 parts of purified water, 1300 parts of propylene glycol, 1300 parts of ganshan, 208 parts of N-120, 208 parts of propanol, 57.2 parts of Emory658, 5.2 parts of Wintergreen, 5.2 parts of Liquid Blue and the balance of purified water.
Specifically, the material is prepared from the following raw materials in percentage by weight: 30.6% of purified water, 25% of propylene glycol, 25% of glycerol, N-1204%, 4% of propanol, 81.1% of Emory651%, 0.1% of Wintergreene, 0.1% of Liquid blue and the balance of purified water.
Specifically, the purified water can be water purifying agent.
The production method of the cow nipple care formula comprises the following steps:
s1, check before work:
s1.1, wearing protective equipment before operation;
s1.2, checking a field and equipment;
s1.3, when liquid materials are added, a weight reduction method is used to ensure the accuracy of the added weight;
s2, before feeding, sampling and detecting the electric conductivity of the purified water and the temperature of the purified water;
s3, putting the materials into a mixing tank to be weighed strictly according to the formula sequence and the proportion and the dosage;
s4, starting stirring for 30 min;
s5, sampling and detecting after stirring;
s6, after the detection is qualified, production and filling are started;
s7, packaging the finished product after filling;
s8, sticking a label;
and S9, packaging, and sampling and weighing.
Specifically, in step S1.1, the user wears a hat, safety glasses, a gas mask, safety gloves, acid and alkali resistant work clothes and acid and alkali resistant leather boots before performing the operation.
Specifically, step S1.2 includes the following steps: confirm that the production place is clean, the raise dust is probably not had, confirm that blending tank, feeding pipe use the clean water thoroughly to wash, whether reinforced pump need the sanitization and the inspection normal operation, whether inspection equipment pipeline, air pipe are normal, whether the used material of inspection is complete.
Specifically, the standard of the purified water conductivity in step S2 is < 30. mu.s/cm, and the temperature of the purified water is < 25 ℃.
Specifically, the weight part of the finished product detected by sampling in step S5 is 300 ml.
Specifically, the product package in step S7 is divided into two specifications, 20ml and 2001.
Specifically, the sampling and weighing rule in step S9 is as follows: and (4) carrying out spot check to confirm the weight of the first five barrels, and weighing according to 20% spot check in the process after the weight is stable.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation. The phrase "comprising a defined element does not exclude the presence of other identical elements in the process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. The formula for nursing the cow nipples is characterized in that: the material is prepared from the following raw materials in parts by mass: 1583.24-1599.16 parts of purified water, 1294-1306 parts of propylene glycol, 1294-1306 parts of glycerol, 202-214 parts of N-120, 202-214 parts of propanol, 56.91-57.49 parts of Emory658, 5.17-5.23 parts of Wintergree, 5.17-5.23 parts of Liquid Blue and the balance of purified water.
2. The bovine nipple care formulation of claim 1, wherein: the material is prepared from the following raw materials in percentage by weight: 30.6% of purified water, 25% of propylene glycol, 25% of glycerol, N-1204%, 4% of propanol, 81.1% of Emory651%, 0.1% of Wintergreene, 0.1% of Liquid blue and the balance of purified water.
3. The bovine nipple care formulation of claim 2, wherein: the purified water can adopt a water purifying agent.
4. A method of producing a bovine teat care formulation according to any one of claims 1-3, characterized in that: the method comprises the following steps:
s1, check before work:
s1.1, wearing protective equipment before operation;
s1.2, checking a field and equipment;
s1.3, when liquid materials are added, a weight reduction method is used to ensure the accuracy of the added weight;
s2, before feeding, sampling and detecting the electric conductivity of the purified water and the temperature of the purified water;
s3, putting the materials into a mixing tank to be weighed strictly according to the formula sequence and the proportion and the dosage;
s4, starting stirring for 20-25 min;
s5, sampling and detecting after stirring;
s6, after the detection is qualified, production and filling are started;
s7, packaging the finished product after filling;
s8, sticking a label;
and S9, packaging, and sampling and weighing.
5. A method of producing a bovine teat care formulation according to claim 4, characterized in that: and step S1.1, wearing a hat, safety glasses, a gas mask, safety gloves, acid and alkali resistant work clothes and acid and alkali resistant leather boots before operation.
6. A method of producing a bovine teat care formulation according to claim 4, characterized in that: step S1.2 comprises the following steps: confirm that the production place is clean, the raise dust is probably not had, confirm that blending tank, feeding pipe use the clean water thoroughly to wash, whether reinforced pump need the sanitization and the inspection normal operation, whether inspection equipment pipeline, air pipe are normal, whether the used material of inspection is complete.
7. A method of producing a bovine teat care formulation according to claim 4, characterized in that: the standard of the purified water conductivity in step S2 is < 30 mus/cm, and the temperature of the purified water is < 25 ℃.
8. A method of producing a bovine teat care formulation according to claim 4, characterized in that: the weight part of the finished product detected by sampling in the step S5 is 300 ml.
9. A method of producing a bovine teat care formulation according to claim 4, characterized in that: the product package in step S7 has two specifications, 20ml and 200l respectively.
10. A method of producing a bovine teat care formulation according to claim 4, characterized in that: the rules for sampling check weighing in step S9 are: and (4) carrying out spot check to confirm the weight of the first five barrels, and weighing according to 20% spot check in the process after the weight is stable.
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| CN202110834652.5A CN113509435A (en) | 2021-07-23 | 2021-07-23 | Formula for nursing cow nipples and production method thereof |
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| CN202110834652.5A CN113509435A (en) | 2021-07-23 | 2021-07-23 | Formula for nursing cow nipples and production method thereof |
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| CN112635079A (en) * | 2020-12-14 | 2021-04-09 | 济南深蓝动物保健品有限公司 | Technical research of povidone iodine film-forming infusion for medicated bath of nipples for preventing mastitis of dairy cows |
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| US5219887A (en) * | 1991-06-07 | 1993-06-15 | Minnesota Mining And Manufacturing Company | Disinfecting shampoo composition for animals |
| US5378731A (en) * | 1991-06-07 | 1995-01-03 | Minnesota Mining And Manufacturing Company | Medicated shampoo |
| US6110908A (en) * | 1995-03-31 | 2000-08-29 | Guthery; B. Eugene | Fast acting and persistent topical antiseptic |
| CN1247223A (en) * | 1998-07-31 | 2000-03-15 | 克罗洛斯公司 | Thickened liquid aqueous cleaning agent based on pine oil |
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Application publication date: 20211019 |