CN101233852A - Fatty acid composition - Google Patents
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- CN101233852A CN101233852A CNA2008100341710A CN200810034171A CN101233852A CN 101233852 A CN101233852 A CN 101233852A CN A2008100341710 A CNA2008100341710 A CN A2008100341710A CN 200810034171 A CN200810034171 A CN 200810034171A CN 101233852 A CN101233852 A CN 101233852A
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Abstract
The invention relates to a fatty acid composition, which is diluted at normal temperature and in cold water to form solution used for cleaning of sterilization, fungicide and antivirus. The fatty acid composition comprises at least the following components: component A: food fatty acid comprising at least octyl decanoic acid and nonanoic acid; component B: surfactant comprising alkane sulfonate; component C: acid. The fatty acid composition has the advantages that the fatty acid composition or the diluted solution thereof has good stability, bactericidal and antiviral activity under the water temperature of 4-20 DEG C, no phase separation or crystallization, thus having safer use performance, and active components are low in cost, having more broad-spectrum bactericidal activity which can kill various bacteria, epiphytes and viruses. The fatty acid composition or the diluted solution thereof can be used for sterilization, fungicide and antivirus, which has high-efficient and quick killing effect; the sterilizing rate can reach more than 99.999 percent with contact time less than 1 minute; The fatty acid composition or the diluted solution thereof also has strong cleaning ability, and can keep effective even in hard water; the killing ratio for poliovirus reaches 99.9999 percent and the poliovirus can be killed immediately.
Description
Technical field
The present invention relates to a kind of aliphatic acid composition, the fatty acid sterilization, the killing fungus, antiviral that are used for sterilization, cleaning, utilize microemulsified and the acid of nanorize technology dissolved fat, be used for the sterilizing of food contacting surface, non-food stuff contact surface, vegetable melon and fruit, public place, household, transportation, fermentation industry, papermaking, pesticidal preparations, livestock breeding food processing industry and water treatment.
Background technology
In view of have pollute and side effect such as carcinogenic contain the widely-used of chloric bactericin preparation and MB soil fumigant, the environment and the ecosystem to human survival produce severe impairment, the disease of current food derived, SARS, bird flu, bacterial resistance etc. are to the aggravation of human health risk simultaneously, be badly in need of exploitation safety, efficient, low-cost, wide spectrum and non-resistance sterilizing product, deal with the preservation problem and the food security of vegetable melon and fruit after people/animal diseases, food/water pollutions, crop/soil germ, the results.
Nineteen eighty-three U.S. skill Kanggong department (ECOLAB) discloses a kind of Cleasing compositions in its U.S. Pat 4404040, comprise fatty acid and ionic solubilizer.Two kinds of main composite formulas in embodiment, have been specifically described, the one, be active ingredient with C8 fatty acid (sad) and the C10 fatty acid (capric acid) that stems from cocoa butter, the 2nd, be active ingredient with C9 fatty acid (n-nonanoic acid) and the C10 fatty acid (capric acid) that stems from vegetable oil, by surface-active stabilizing agent octyl sulfonate, citric acid, phosphoric acid and water, make the pH value at 2～5 emulsifying composition, said composition can effectively be killed at bacteriums such as gram-positive staphylococcus aureus and gram-negative Escherichia coli.Thereby the acid disinfectant of a kind of flushing-free of the commodity Mandate by name that have been born.Commercially available Mandate contains 8% food grade fats acid of drugs approved by FDA, comprises 4.8% C8 and 3.2% C10 fatty acid, and citric acid and phosphoric acid, and commercial applications is in the cleaning and disinfection sterilization of food processing equipment, hospital, environment and livestock breeding.Under the extension rate that sets (640 times dilution or 1 ounce convert water to 5 gallon), the valid density of C8-C10 fatty acid is about 120～150ppm, and 25 ℃ of normal temperature are issued to 99.999% sterilizing rate (logarithm value 〉=5).
All activity and inert component all by the raw material of drugs approved by FDA use in food contacting surface, can search from U.S. FDA 21 CFR178.1010 clauses among the Mandate.Under U.S. food quality protection bill in 1996 is stipulated, be included under U.S. EPA 40CFR 180.940 clauses and manage.
But there is following defective in Mandate: the one, under low-temperature storage, shown that C8-C10 fatty acid can be separated; In addition, under 4 ℃ of cold water dilutions, because the crystallization meeting of C8 and C10 fatty acid makes bactericidal activity descend.
Mention Mandate and have not good storage stability in U.S. Pat 5391379, can be separated under room temperature or low temperature, unless add a large amount of relatively costly additives, as citric acid, but this can not increase its bactericidal activity yet.
In order to improve the low-temperature storage stability of fatty acid bactericidal composition, a notion that adds the weak acid stabilizing agent has been proposed in this invention, this weak acid comprises propionic acid, butyric acid, valeric acid.What announced concrete prescription in an embodiment is 3% C9,3% C10,8～10% activating agent octyl sodium sulfonate and octyl sodium disulfonate, 8～30% strong acid, 10% weak acid propionic acid.
Said composition when contacting with crust, in due course between and under the temperature condition splendid microbial activity is arranged all, and bactericidal effect is good.
From the table 1 of this invention as can be known, composition comprises C8, C10, octyl sulfonate, phosphoric acid, composition is not separated at normal temperatures after adding weak acid such as propionic acid or butyric acid, but under 0 ℃, have only and adopt propionic acid and/or butyric acid, and it reaches at 10% o'clock at consumption and just can not be separated, and using separately and consumption only is can be separated in 5% o'clock, mix when using at propionic acid and butyric acid, total consumption can not be separated when above 6%.
But whether the adding that propionic acid and/or butyric acid are not discussed in this invention can prevent whether the C8-C10 composition from after the cold water dilution, especially can also keep non-crystallizable at low temperatures when the working concentration that is diluted to 0.2%.Trend from table 1, whether the consumption of weak acid and C8-C10 composition can be separated at low temperatures is closely-related, the concentration of weak acid reduces will cause the generation that is separated, therefore be difficult to guarantee that this aliphatic acid composition still can keep low temperature not to be separated being diluted at 0.2% o'clock, or non-crystallizable.And because the interpolation of propionic acid, butyric acid can produce the strong impulse flavor, thereby limited its application in some aspects.
U.S. skill Kanggong department further exploitation on the basis of its original patent in 2002, a kind of fatty acid bactericidal composition is disclosed in its U.S. Pat 6472358, comprise at least a amount of carbon atom at 5～14 fatty acid, amount of carbon atom is at 1～4 weak carbonic acid, and strong acid, be the combination of nitric acid or nitric acid and sulfonic acid.
Point out that in its summary of the invention in the presence of nitric acid, said composition is at conc forms or be diluted under the situation of using solution and all show splendid phase stability, and especially good phase stability is arranged also in the water at low temperature dilution.
Described the aliphatic acid composition of a kind of C9-C10 in concrete manifestation, wherein the C9 consumption is 4～8%, and the C10 consumption is 1～3%.It is pointed out in the C9-C10 composition, increases the consumption of C9, and the consumption of reduction C10 can improve the stability of composition.Released the upgrading preparation of Mandate thus, Mandate Plus, and successfully push market, commercially available MandatePlus preparation include 6.49% C9 and 1.09% C10 fatty acid, and acetate, nitric acid and phosphoric acid.
But the consumption that reduces C10 also has its drawback, because the low content of C10 fatty acid, its sterilizing ability to staphylococcus aureus has lowered, and does not have the activity index under the dilution of data show said preparation cold water.
More peroxide fatty acid bactericidal composition patent also comprises the U.S. Pat 5200189 of U.S. skill Kanggong department, US5314687 and US5718910, what it was mainly discussed is a kind of peroxy acid bactericidal composition, mainly comprise carbon number at 1～4 peroxy acid, carbon number is at 5～17 the peroxide fatty acid that comprises the RCOOOH structure.
The commercial goods Vortexx or the Matri xx of skill Kanggong department comprise 3.3% C8,4.4% Peracetic acid and 6.9% hydrogen peroxide.Sad and hydroperoxidation forms more active Peroxycaprylic acid.
The Vortexx product has activity and uses the back flushing-free under 400～800 times of dilutions.But shortcoming is that the Peracetic acid price comparison in the composition is expensive, and performs poor in employed short chain octane anion active agent cleaning force difference and the hard water.
Summary of the invention
Technical problem to be solved by this invention is at above-mentioned weak point, a kind of aliphatic acid composition is provided, be used for sterilizing and anti-virus, said composition is at concentrated product or be diluted under the situation of using solution and all have good low-temperature storage stability, and sterilization and antiviral activity.
The present invention solves the problems of the technologies described above the technical scheme of being taked: a kind of aliphatic acid composition, and be diluted in and form sterilization, killing fungus, antiviral cleaning solution in normal temperature and the cold water, comprise following component at least:
The A component is food grade fats acid: comprise hot capric acid C8-C10 and n-nonanoic acid C9 at least, for practical operation, also can also contain a spot of caproic acid and lauric acid etc. in the fatty acid;
The B component is surfactant: comprise alkylsulfonate;
The C component is an auxiliary agent with acid, in order to improving storage stability and dilution stability, and removes pungent taste;
Applicant of the present invention has studied the low temperature crystallization situation of commercially available fatty acid goods, and is as shown in table 1.
Table 1
| Emery 657 (C8) | Emery 658 (C8-C 10) | Emery 1202 (C9) | Emery 658/1202 (C8-C10∶C9＝75∶25) | Emery 658/1202 (C8-C10∶C9＝50∶50) | |
| Congealing point ℃ | 14～16 | 1～6 | 8～11 | - | - |
| 4 ℃ of storages | |||||
| 1 day | Crystallization | Liquid | Crystallization | Liquid | Liquid |
| 3 days | Crystallization | Liquid | Liquid | ||
| 1 week | Crystallization | Liquid | |||
The Emery fatty acid of each model is purchased in U.S. Ke Ning company (CognisCorporation)
As shown in Table 1, C8, C9 that the C8-C9-C10 fatty acid mixed is more simple, or the composition of C8-C10 has lower crystallization temperature, C8-C10: the C9 weight ratio is 50: 50 o'clock, and composition stores at low temperatures and a week crystallization can not occur.
Described surfactant is the anion surfactant alkylsulfonate, can be mersolates and/or alkyl sulfonic acid sylvite, also can be alkylnaphthalene sulfonate.
On the basis of such scheme, described C component comprises a kind of or its combination in lactic acid, phosphoric acid, propionic acid, the HEDP.
Hot capric acid C8-C10 in the described A component and the weight ratio of n-nonanoic acid C9 are 20: 80～80: 20.Be specifically as follows 20: 80,25: 75,30: 70,35: 65,40: 60,45: 55,50: 50,55: 45,60: 40,65: 35,70: 30,75: 25, a kind of in 80: 20.
Wherein, the ratio of the consumption of hot capric acid and n-nonanoic acid is preferably 40: 60～and 60: 40, be at 50: 50 the best especially with amount ratio.
On the basis of such scheme, provide a kind of described composition to comprise following component by weight percentage:
Hot capric acid and n-nonanoic acid 4～12%
Sulfonate 25～40%
Lactic acid 15～20%
Phosphoric acid 3 0～40%
Water or deionized water balance amount.
The present invention provides a kind of described composition again, comprises following component by weight percentage:
Hot capric acid and n-nonanoic acid 4～12%
Sulfonate 25～40%
Lactic acid 40～50%
Water or deionized water balance amount.
The present invention also provides a kind of described composition, comprises following component by weight percentage:
Hot capric acid and n-nonanoic acid 4～12%
Sulfonate 25～40%
Propionic acid 10～20%
Phosphoric acid 30～40%
Water or deionized water balance amount.
Wherein, food grade fats acid: the consumption of hot capric acid and n-nonanoic acid mixture (%) by weight percentage can be specially 4,4.2,4.5,4.8,5,5.3,5.5,5.7,6,6.2,6.5,6.8,7,7.2,7.5,7.8,8,8.3,8.5,8.7,9,9.2,9.5,9.8,10,10.5,10.8, a kind of in 11,11.2,11.5,11.8,12.
Surfactant: the consumption of alkylsulfonate (%) by weight percentage is specifically as follows 25,25.5,26,26.5,27,27.5,28,28.5,29,29.5,30,30.5,31,31.5,32,32.5,33,33.5,34,34.5,35,35.5,36,36.5,37,37.5, a kind of in 38,38.5,39,39.5,40%.
Other acid comprises that lactic acid is the lactic acid of commercially available concentration 88%, and phosphoric acid is phosphoric acid and/or other acid of commercially available concentration 75%, with water or deionized water balance.
Present composition prescription difference with the prior art is the mixture of having taked sad C8, n-nonanoic acid C9, capric acid C10 that the present invention is breakthrough, and adopt alkylsulfonate as surfactant or title solubilizer, alkylsulfonate is that a kind of superior moistening and cleaning agent and tool toxotest data are oral LD50 (rat)＞5000mg/kg, and it all has the dissolution of height under stoste and dilution to C8-C9-C10 fatty acid.
On this basis, the present invention uses the lactic acid of food-grade and phosphoric acid to dilute, and also can comprise the weak acid propionic acid, further increases its storage stability.The limpid microemulsified stoste bactericidal composition of making is proved to be at 4 ℃ of following these aliphatic acid compositions of low temperature all liquid phase separation can not occur.At 500ppm hard water (500ppm calcium/magnesium ion; Heavy metal ion not only can reduce stability but also can reduce the activity of fatty acid) and 4 ℃ water temperature under, 0.1% and 0.2% diluted concentration all shows the solution that is limpid, and crystalline polamer does not appear in aliphatic acid composition yet after 24 hours.In the present invention, acid can also comprise strong acid such as weak acid such as citric acid, glycolic acid, nitric acid, sulfonic acid, but and inessential.
Described composition may further include hydrogen peroxide, hydrogen peroxide itself is a kind of strong oxidizer with bactericidal effect, hydrogen peroxide and fatty acid response generate peroxide fatty acid, has good bactericidal property, therefore in this prescription, comprised two kinds of active ingredients: C8-C9-C10 fatty acid and hydrogen peroxide are to form C8-C9-C10 peroxide fatty acid.Thus, fatty acid bactericidal composition of the present invention no longer needs to add the peroxy acid of Peracetic acid class.Because Peracetic acid cost costliness; so the inventive method can reduce product cost greatly; and the use of surfactant alkylsulfonate has very positive effect to the formation that promotes highly active peroxide fatty acid; under the situation that sulfonate exists; active peak value can reach at 1～5 day, and these discoveries Kanggong department patent needs that are better than planting just can reach active peak value in 12 days.
On the basis of such scheme, provide a kind of described composition to comprise following component by weight percentage:
Hot capric acid and n-nonanoic acid 4～12%
Alkylsulfonate 25～40%
Propionic acid 20～50%
HEDP 0～5%
Hydrogen peroxide 20～50%
Water or deionized water balance amount.
Purposes at above-mentioned nontoxic fatty acid sterilization and virucidal compositions is used for sterilization, killing fungus, antiviral, kills a kind of or its combination in gold look staphylococcus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa, the polyovirus.
In the description of prior art, only be the research that gold look staphylococcus, colibacillary sterilization conditions are carried out, and the present invention further should be used as careful analysis to of the present invention on the basis to sterilization research.Find that through experiment the present invention all has splendid killing effect to bacterium, fungi, virus, makes that the adaptable scope of the present invention is more wide.
The invention has the beneficial effects as follows:
1, aliphatic acid composition of the present invention all has advantages of excellent stability and sterilization, antiviral activity under 4～20 ℃ of water temperatures under stoste or diluting condition, can not be separated, or crystallization;
2, aliphatic acid composition of the present invention has safer serviceability, and active ingredient is with low cost, and mouse acute oral toxicity index (LD50) is 5840mg/kg;
3, aliphatic acid composition of the present invention has the more bactericidal activity of wide spectrum, can kill various bacteriums, fungi and virus;
4, aliphatic acid composition of the present invention can be used for sterilization, killing fungus and antiviral, has the ability of killing efficiently and rapidly, sterilizing rate can reach more than 99.999%, less than 1 minute time of contact, and has strong cleaning capacity, rendeing a service in hard water and still do not subtract, is 99.9999% for the killing rate of polyovirus, kills immediately.
Embodiment
A kind of nontoxic fatty acid sterilization and virucidal compositions are diluted in the cleaning solution that forms sterilization, killing fungus and virus in normal temperature and the cold water, wherein comprise at least:
A component: be food grade fats acid: comprise hot capric acid and n-nonanoic acid at least;
B component: be surfactant: comprise alkylsulfonate;
C component: be acid.
Described acid comprises a kind of or its combination in lactic acid, phosphoric acid, propionic acid, the HEDP.
Fatty acid is commercially available Emery 658 (hot capric acid C8-C10) and Emery 1202 (n-nonanoic acid C9), purchases in U.S. Ke Ning company (Cognis Corporation).Emery 658/1202 (50/50) mixture includes about 31% C8,47% C9 and 21% C10, adds 1% caproic acid C6 and lauric acid C12 fatty acid.
Embodiment 1
Emery 658 (C8-C10) is 50: 50 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 1# | 2# | 3# | |
| Emery 658/1202(50/50) | 10 | 10 | 10 |
| Alkylsulfonate | 35 | 35 | 35 |
| Lactic acid (88%) | 50 | 20 | - |
| Propionic acid | - | - | 20 |
| Phosphoric acid (75%) | - | 35 | 30 |
| Deionized water | 5 | - | 5 |
| 4 ℃ store a week | Dissolving | Dissolving | Dissolving |
| 0.2% dilution (500ppm hard water, 4 ℃ store 24 hours) | Dissolving | Dissolving | Dissolving |
Emery 658/1202 (50/50) mixture includes about 31% C8,47% C9 and 21% C10, adds 1% C6 and C12 fatty acid.
Embodiment 2
Emery 658 (C8-C10) is 60: 40 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 1# | 2# | 3# | |
| Emery 658/1202(60/40) | 10 | 10 | 10 |
| Alkylsulfonate | 35 | 35 | 35 |
| Lactic acid (88%) | 50 | 20 | - |
| Propionic acid | - | - | 20 |
| Phosphoric acid (75%) | - | 35 | 30 |
| Deionized water | 5 | - | 5 |
| 4 ℃ store a week | Dissolving | Dissolving | Dissolving |
| 0.2% dilution (500ppm hard water, 4 ℃ store 24 hours) | Dissolving | Dissolving | Dissolving |
Embodiment 3
Emery 658 (C8-C10) is 40: 60 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 1# | 2# | 3# | |
| Emery 658/1202(40/60) | 10 | 10 | 10 |
| Alkylsulfonate | 35 | 35 | 35 |
| Lactic acid (88%) | 50 | 20 | - |
| Propionic acid | - | - | 20 |
| Phosphoric acid (75%) | - | 35 | 30 |
| Deionized water | 5 | - | 5 |
| 4 ℃ store a week | Dissolving | Dissolving | Dissolving |
| 0.2% dilution (500ppm hard water, 4 ℃ store 24 hours) | Dissolving | Dissolving | Dissolving |
Embodiment 4
Emery 658 (C8-C10) is 20: 80 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 1# | 2# | 3# | |
| Emery 658/1202(20/80) | 10 | 10 | 10 |
| Alkylsulfonate | 35 | 35 | 35 |
| Lactic acid (88%) | 50 | 20 | - |
| Propionic acid | - | - | 20 |
| Phosphoric acid (75%) | - | 35 | 30 |
| Deionized water | 5 | - | 5 |
| 4 ℃ store a week | Dissolving | Dissolving | Dissolving |
| 0.2% dilution (500ppm hard water, 4 ℃ store 24 hours) | Dissolving | Dissolving | Dissolving |
Embodiment 5
Emery 658 (C8-C10) is 80: 20 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 1# | 2# | 3# | |
| Emery 658/1202(80/20) | 10 | 10 | 10 |
| Alkylsulfonate | 35 | 35 | 35 |
| Lactic acid (88%) | 50 | 20 | - |
| Propionic acid | - | - | 20 |
| Phosphoric acid (75%) | - | 35 | 30 |
| Deionized water | 5 | - | 5 |
| 4 ℃ store a week | Dissolving | Dissolving | Dissolving |
| 0.2% dilution (500ppm hard water, 4 ℃ store 24 hours) | Dissolving | Dissolving | Dissolving |
Embodiment 6
Emery 658 (C8-C10) is 50: 50 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 1# | 2# | 3# |
| Emery 658 | 4.5 | 5 | 5.5 |
| Emery 1202 | 4.5 | 5 | 5.5 |
| Alkylsulfonate | 30 | 35 | 39 |
| Lactic acid (88%) | 26 | 15 | 20 |
| Phosphoric acid (75%) | 35 | 40 | 30 |
| 4 ℃ store a week | Dissolving | Dissolving | Dissolving |
| 0.2% dilution (500ppm hard water, 4 ℃ store 24 hours) | Dissolving | Dissolving | Dissolving |
Embodiment 7
Emery 658 (C8-C10) is 50: 50 with the weight ratio of Emery 1202 (C9), and each prescription is (wt%) meter by weight percentage:
| 4# | 5# | 6# | |
| Emery 658/1202(50/50) | - | 5 | 5 |
| Alkylsulfonate | - | 25 | 25 |
| Propionic acid | - | 20 | 20 |
| HEDP | - | 1 | 1 |
| Hydrogen peroxide (35%) | 34.3 | - | 34.3 |
| Deionized water | 65.6 | 49 | 14.7 |
| 4 ℃ store a week | - | Dissolving | Dissolving |
| 0.1% dilution (342ppm hard water) | - | Dissolving | Dissolving |
The HEDP buying is from profit source, Changzhou chemical industry Co., Ltd.
Application experiment 1
1.1 to staphylococcus aureus and colibacillary killing effect
1.1.1 test condition: adopt Ministry of Public Health's " disinfection technology rule " version standard in 2002,30 seconds times of contact, dilution is a 342ppm hard water.
1.2 experimental subjects is 1#, 2#, 3# fatty acid bactericidal composition among the embodiment 1
1.2.1 experimental result
Table 2
| Diluted concentration (%) | Water temperature (℃) | Staphylococcus aureus killing rate (%) | Escherichia coli (%) | |
| 1# | 0.1 | 25 | 93.644 | 95.880 |
| 0.2 | 25 | 99.999 | 99.998 | |
| 2# | 0.1 | 25 | 99.800 | 99.659 |
| 0.2 | 25 (contacting 60 seconds) | 99.999 | 99.999 | |
| Quickened in 1#54 ℃/14 days | 0.2 | 25 | 99.999 | 99.999 |
| Quickened in 2#54 ℃/14 days | 0.2 | 25 | 99.999 | 99.999 |
| 3# | 0.2 | 25 | 97.972 | 95.533 |
1.2.2 experiment conclusion
Under 500 times of dilutions (w/w), preparation 2# has more activity than preparation 1# and 3#, and under 60 seconds time of contact, and the killing rate of Escherichia coli and staphylococcus aureus is reached 99.999%, and the moment killing rate of virus is reached logarithm value 6.
Adopt alkyl sulfonate surfactants, 2# composition under 500 times of dilutions, to obtain the pH value, make it have good cost benefit and effective acid sterilization/cleaning function at 2.5 dilution.And the 1# composition uses soft lactic acid to make the product responsive to pH value, to the sterilization cleaning on fruit and leaves of plants surface, and all is very useful to family, hospital.
In quickening experiment, 1# of the present invention, 2# preparation be by quickening experiment, still can reach 99.999% to the killing rate of Escherichia coli and staphylococcus aureus, illustrates that this product can satisfy the requirement of preserving at normal temperature 1 year.
So-called acceleration experiment be exactly with test specimen after initial bactericidal effect passes through, put into heating cabinet after depositing 14 days under 54 ℃, assess its bactericidal activity again, if it is still qualified, to represent this product can preserve at normal temperatures 1 year, being exactly usually said shelf life of products, is the generic principles of all chemical products assessment shelf-lifves basically.
1.3 experimental subjects is 5#, 6# fatty acid bactericidal composition among the embodiment 7, is Comparative Examples with the 4# hydrogen peroxide
1.3.1 experimental result
Table 3
| Time (my god) | Diluted concentration (%) | Water temperature (℃) | Staphylococcus aureus killing rate (%) | Escherichia coli killing rate (%) | |
| 4# | 1 | 0.1 | 20 | 76.750 | 73767 |
| 5# | 1 | 0.1 | 20 | 97.867 | 77.395 |
| 6# | 1 | 0.1 | 20 | 99.9998 | 99.9967 |
| 5 | 0.1 | 20 | 99.9999 | 99.9999 | |
| 10 | 0.1 | 20 | 100 | 99.9990 | |
| 10 | 0.1 | 4 | 99.9999 | 99.9999 | |
| 10 | 0.75 | 4 | 99.9999 | 99.9999 | |
| 10 | 0.5 | 4 | 99.9988 | 99.9999 | |
| 20 | 0.1 | 20 | 99.9999 | 99.9999 | |
| 30 | 0.1 | 20 | 99.9998 | 99.9999 |
The 6# product has high activity under 4 ℃ and 20 ℃ of water temperatures and 1000～2000 times of dilutions.It stores one month at 20 ℃ and stablizes.This bactericidal composition satisfies the cost benefit requirement to a sterilization and sterile products, and has great application potential in industrial and agricultural productions such as food processing, crops, environment.
Application experiment 2
2.1 killing effect to Candida albicans and Pseudomonas aeruginosa
2.2 test condition: adopt Ministry of Public Health's " disinfection technology rule " version standard in 2002,7.5 minutes times of contact, dilution is a 342ppm hard water.
2.3 experimental subjects is the 2# fatty acid bactericidal composition among the embodiment 1
2.4 experimental result
Table 4
| Diluted concentration (%) | Water temperature (℃) | Candida albicans killing rate (%) | Pseudomonas aeruginosa killing rate (%) | |
| 2# | 0.35 | 25 | 99.999 | 99.999 |
2.5 experimental result
2# preparation killing rate to white beads and Pseudomonas aeruginosa under 300 times of dilutions (w/w) all reaches 99.999%.
Application experiment 3
3.1 killing effect to polyovirus
3.2 test condition: adopt the traditional Chinese medicines prison to annotate [2002] No. 160, the moment contact, dilution is a distilled water.
3.3 experimental subjects is the 2# fatty acid bactericidal composition among the embodiment 1
3.4 experimental result
Table 5
| Diluted concentration (%) | Water temperature (℃) | Polyovirus killing rate (%) | |
| 2# | 0.2 | 25 | 99.9999 |
3.5 experiment conclusion
The present invention has the property killed very efficiently to poliomyelitis virus, and logarithm value reaches 6, this shows that composition of the present invention all has good killing effect for bacterium, fungi, virus.
Claims (9)
1, a kind of aliphatic acid composition is diluted in and forms sterilization, killing fungus, antiviral cleaning solution in normal temperature and the cold water, comprises following component at least:
A component: be food grade fats acid, comprise hot capric acid and n-nonanoic acid at least;
B component: be surfactant, comprise alkylsulfonate;
C component: be acid.
2, aliphatic acid composition according to claim 1 is characterized in that: described acid comprises a kind of or its combination in lactic acid, phosphoric acid, propionic acid, the HEDP.
3, aliphatic acid composition according to claim 1 is characterized in that: hot capric acid and the weight ratio between n-nonanoic acid in the described A component are 20: 80～80: 20.
4, according to the described aliphatic acid composition of one of claim 1 to 3, it is characterized in that: described composition comprises following component by weight percentage:
(a) hot capric acid and n-nonanoic acid 4～12%
(b) sulfonate 25～40%
(c) lactic acid 15～20%
(d) phosphoric acid 30～40%
(f) water or deionized water balance amount.
5, according to the described aliphatic acid composition of one of claim 1 to 3, it is characterized in that: in the described composition, comprise following component by weight percentage:
(a) hot capric acid and n-nonanoic acid 4～12%
(b) alkylsulfonate 25～40%
(c) lactic acid 40～50%
(d) water or deionized water balance amount.
6, according to the described aliphatic acid composition of one of claim 1 to 3, it is characterized in that: described composition comprises following component by weight percentage:
(a) hot capric acid and n-nonanoic acid 4～12%
(b) sulfonate 25～40%
(c) propionic acid 10～20%
(d) phosphoric acid 30～40%
(e) water or deionized water balance amount.
7, according to the described aliphatic acid composition of one of claim 1 to 3, it is characterized in that: described composition further comprises hydrogen peroxide.
8, aliphatic acid composition according to claim 7 is characterized in that: described composition comprises following component by weight percentage:
(a) hot capric acid and n-nonanoic acid 4～12%
(b) alkylsulfonate 25～40%
(c) propionic acid 20～50%
(d) HEDP 0～5%
(e) hydrogen peroxide 20～50%
(f) water or deionized water balance amount.
9, at the described application of fatty acid composition of claim 1, be used for sterilization, killing fungus, antiviral, kill a kind of or its combination in gold look staphylococcus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa, the polyovirus.
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