CN113341125A - Reagent card structure, collude card mechanism and fluorescence immunoassay appearance - Google Patents
Reagent card structure, collude card mechanism and fluorescence immunoassay appearance Download PDFInfo
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- CN113341125A CN113341125A CN202011504615.XA CN202011504615A CN113341125A CN 113341125 A CN113341125 A CN 113341125A CN 202011504615 A CN202011504615 A CN 202011504615A CN 113341125 A CN113341125 A CN 113341125A
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- hooking
- reagent card
- card body
- card
- sample
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5302—Apparatus specially adapted for immunological test procedures
- G01N33/5304—Reaction vessels, e.g. agglutination plates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
Abstract
The invention belongs to the technical field of protein analyzers and discloses a reagent card structure, a card hooking mechanism and a fluorescence immunoassay analyzer. This reagent card structure, including the reagent card body, be provided with the breach in the bottom of reagent card body, the breach is including feeding portion and colluding the card portion, and feeding portion sets up along the first direction, colludes the card portion and sets up along the second direction, feeds portion and colludes the mutual intercommunication of card portion to form L shape structure, wherein first direction and second direction mutually perpendicular. The reagent card body of this reagent card structure only needs collude card mechanism and just can realize the operation along first direction and second direction removal, compares in the current three direction that needs, has simplified operation action and process, has reduced manufacturing cost effectively. Meanwhile, the feeding portion and the hooking portion are communicated with each other, so that the hooking mechanism can slide into the hooking portion through the feeding portion, and the feeding portion and the hooking portion play a role in guiding the hooking mechanism.
Description
Technical Field
The invention relates to the technical field of protein analyzers, in particular to a reagent card structure, a card hooking mechanism and a fluorescence immunoassay analyzer.
Background
With the continuous progress of the medical level of society, in recent years, fluorescence immunoassay analyzers have come to be widely used in various large and medium hospitals, and provide essential information basis for the diagnosis, treatment, prevention and health status of diseases in clinic.
As shown in fig. 1, the currently mainstream fluorescence immunoassay analyzer is used with a specific reagent card 100 ', and the reagent card 100' is transported from the reagent card to each station through the card hooking module. Most of the existing reagent cards 100 'are provided with a notch 200' with a rectangular structure at the bottom, a card hooking module matched with the reagent card 100 'needs to move in X, Y and Z directions, the card hooking module needs to move to a reagent card position along an X direction and then move along a Y direction, and after the card hooking module is aligned with the notch 200' at the bottom of the reagent card 100 ', the card hooking module moves along the Z direction, so that the card hooking module hooks the reagent card 100'.
Because the notch 200 ' is a mouth with closed periphery, most analyzers need the motion of XYZ three directions to the operation of reagent card 100 ', realize the operation of reagent card 100 ' in the machine, cause the space layout requirement of colluding the card module to the fluorescence immunoassay analyzer big, and the three directions of XYZ need three motor drive, manufacturing cost is high.
Disclosure of Invention
The invention aims to provide a reagent card structure, a card hooking mechanism and a fluorescence immunoassay analyzer, which have the advantages of simplified structure, small occupied space and low production cost.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a reagent card structure, includes the reagent card body the bottom of reagent card body is provided with the breach, the breach is including feeding portion and colluding the card portion, feeding portion sets up along the first direction, collude the card portion and set up along the second direction, feeding portion with collude the mutual intercommunication of card portion to form L shape structure, wherein the first direction with second direction mutually perpendicular.
Preferably, the reagent card body is provided with a sample addition port for adding a sample to the reagent card body and an optical detection port for detecting the reagent card body.
In order to achieve the above object, the present invention further provides a card hooking mechanism for conveying the reagent card structure, wherein the card hooking mechanism comprises:
the first moving assembly is connected with the card hooking assembly and is configured to drive the card hooking assembly to enter the feeding part of the reagent card body along a first direction and be in sliding fit with the feeding part;
the second moving assembly is connected to the first moving assembly and is configured to drive the first moving assembly to drive the card hooking assembly to move along the second direction into the card hooking part of the reagent card body and to be in sliding fit with the card hooking part, so that the first moving assembly can drive the card hooking assembly and the reagent card body to move along the first direction.
Preferably, the reagent card further comprises a limiting block, the limiting block is arranged on the first moving assembly, a limiting cavity is formed in the limiting block along the first direction, the reagent card body can be in sliding fit with the limiting cavity, and the limiting cavity is used for limiting the reagent card body.
Preferably, the hooking and fastening assembly includes:
the hook rod is inserted into the notch of the reagent card body, and the hook rod penetrates through the limiting cavity and is in sliding fit with the limiting cavity;
and the first sliding block is connected to the first moving assembly and the hook rod.
Preferably, the hooking and fastening assembly further comprises:
the connecting block is connected to the hook rod;
one end of the connecting rod is connected to the first sliding block, and the other end of the connecting rod penetrates through the connecting block and is in sliding fit with the connecting block;
the reset piece is sleeved on the connecting rod, and two ends of the reset piece can respectively abut against the connecting block and the first sliding block.
Preferably, the first moving assembly includes a first driving source, a first driving wheel, a first driven wheel and a first conveyor belt, the first conveyor belt is respectively tensioned and wound on the first driving wheel and the first driven wheel and connected to the hooking assembly, an output end of the first driving source is connected to the first driving wheel, and the first driving source can drive the first driving wheel to rotate and drive the first driven wheel to rotate and the first conveyor belt and the hooking assembly to move.
Preferably, the second moving assembly includes a second driving source, a second driving wheel, a second driven wheel and a second conveying belt, the second conveying belt is respectively tensioned around the second driving wheel and the second driven wheel and connected to the first moving assembly, an output end of the second driving source is connected to the second driving wheel, and the second driving source can drive the second driving wheel to rotate and drive the second driven wheel to rotate and the second conveying belt and the hook component to move.
In order to achieve the above object, the present invention further provides a fluorescence immunoassay analyzer, which includes a sample feeding mechanism, an incubation mechanism, and the card hooking mechanism, wherein the sample feeding mechanism is used for carrying a sample, the sample feeding mechanism is used for placing the sample in a sample feeding port of the reagent card body, the card hooking mechanism is used for inserting into a notch of the reagent card body and conveying the reagent card body to the incubation mechanism, and the incubation mechanism is used for incubating the reagent card body with the sample.
Preferably, the kit further comprises a detection mechanism, wherein the detection mechanism is arranged on the card hooking mechanism and is used for detecting the reagent card body which completes incubation.
The invention has the beneficial effects that:
according to the reagent card structure provided by the invention, the notch is formed in the bottom of the reagent card body, the feeding part of the notch is arranged along the first direction, and the hooking part of the notch is arranged along the second direction, so that the reagent card body can be operated only by moving the hooking mechanism along the first direction and the second direction. Meanwhile, the feeding portion is used for feeding the card hooking mechanism, the card hooking mechanism can conveniently enter the notch initially, the card hooking portion is used for hooking the card hooking mechanism, the feeding portion and the card hooking portion are communicated mutually, the card hooking mechanism can slide into the card hooking portion through the feeding portion, the feeding portion and the card hooking portion play a role in guiding the card hooking mechanism, the moving path of the card hooking mechanism is limited, compared with the rectangular notch, the accommodating space of the notch of the L-shaped structure is small, the limiting effect of the card hooking mechanism is good, and the situation that the card hooking mechanism moves randomly in the notch is avoided.
According to the hooking mechanism provided by the invention, the first moving component drives the hooking component to move along the first direction, so that the hooking component enters the feeding part from the notch, then the second moving component drives the hooking component to enter the hooking part along the second direction through the first moving component, so that the hooking component hooks the reagent card body, and after hooking, the first moving component can drive the hooking component and drive the reagent card body to move along the first direction, so that the reagent card body is conveyed. Because the moving direction of the first moving assembly is perpendicular to the extending direction of the hooking part, the fixing effect between the hooking assembly and the reagent card body is good. Meanwhile, the hooking mechanism only needs the movement of the first moving assembly and the second moving assembly in two directions, so that the production cost is saved, the layout is compact, the occupied area is small, and the space utilization rate is maximized.
According to the fluorescence immunoassay analyzer provided by the invention, after a sample is placed on the sample introduction mechanism, the card hooking mechanism is used for inserting the notch of the reagent card body and conveying the notch, the sample adding mechanism is used for placing the sample in the sample adding port of the reagent card body, the card hooking mechanism can be used for incubating the reagent card body with the sample, and the incubation mechanism is used for incubating the reagent card body with the sample. Through the mutual cooperation of the sample feeding mechanism, the sample adding mechanism, the incubation mechanism and the card hooking mechanism, the operation process of the reagent card body is continuous and gapless, and the production efficiency is higher.
Drawings
FIG. 1 is a schematic diagram of a prior art reagent card;
FIG. 2 is a schematic diagram of one perspective of a reagent card configuration of the present invention;
FIG. 3 is a schematic representation of another perspective of a reagent card configuration of the present invention;
FIG. 4 is a schematic view of the configuration of the fluorescence immunoassay analyzer of the present invention;
FIG. 5 is a schematic structural diagram of a card hooking mechanism in the fluorescence immunoassay analyzer of the present invention;
FIG. 6 is a schematic structural diagram of the first moving assembly and the hooking assembly in the fluorescence immunoassay analyzer of the present invention.
In the figure:
100', reagent card; 200', a notch;
100. a reagent card body; 200. a notch; 201. a feeding section; 202. a hooking part; 300. a sample addition port; 400. an optical detection port;
001. an incubation station; 002. a reagent card station; 003. a card withdrawing station;
1. a hooking mechanism; 2. a sample introduction mechanism; 3. a sample adding mechanism; 4. an incubation mechanism; 5. a limiting block; 6. a detection mechanism; 7. a frame; 8. a housing; 9. a position sensor;
11. a first moving assembly; 12. a hooking and clamping component; 13. a second moving assembly;
111. a first mounting plate; 112. a first drive source; 113. a first drive wheel; 114. a first conveyor belt; 115. a first guide rail;
121. a hook rod; 122. a first slider; 123. connecting blocks; 124. a connecting rod; 125. a reset member;
131. a second mounting plate; 132. a second drive source; 133. a second driven wheel; 134. a second conveyor belt; 135. a second guide rail;
41. an incubation platform; 411. an incubation cavity; 51. and a limiting cavity.
Detailed Description
In order to make the technical problems solved, technical solutions adopted and technical effects achieved by the present invention clearer, the technical solutions of the embodiments of the present invention will be described in further detail below with reference to the accompanying drawings, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
In the description of the present invention, unless expressly stated or limited otherwise, the terms "connected," "connected," and "fixed" are to be construed broadly, e.g., as meaning permanently connected, removably connected, or integral to one another; can be mechanically or electrically connected; either directly or indirectly through intervening media, either internally or in any other relationship. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly under and obliquely below the second feature, or simply meaning that the first feature is at a lesser elevation than the second feature.
The technical scheme of the invention is further explained by the specific implementation mode in combination with the attached drawings.
As shown in fig. 1, a rectangular notch 200 ' is formed in a conventional reagent card 100 ', and since the rectangular notch 200 ' is a closed opening, motors need to be respectively disposed in X, Y and Z directions to move the reagent card 100 ' in the X direction, the Y direction and the Z direction, respectively, so as to operate the reagent card 100 ', but the number of motors is large, the occupied space is large, and the problems of difficulty in spatial arrangement and high production cost exist.
In order to solve this problem, the present embodiment provides a reagent card structure, as shown in fig. 2, the reagent card structure includes a reagent card body 100, a notch 200 is provided at the bottom of the reagent card body 100, the notch 200 includes a feeding portion 201 and a hooking portion 202, the feeding portion 201 is disposed along a first direction, the hooking portion 202 is disposed along a second direction, and the feeding portion 201 and the hooking portion 202 are communicated with each other to form an L-shaped structure. The shape of the reagent card body 100 is similar to a cuboid structure, the length direction of the reagent card body 100 is defined as a first direction, the width direction of the reagent card body 100 is defined as a second direction, and the first direction and the second direction are perpendicular to each other. It should be noted that the first direction and the second direction only represent spatial directions and have no substantial meaning.
The reagent card structure that this embodiment provided is provided with breach 200 in the bottom of reagent card body 100, and the portion 201 of feeding along the first direction setting of breach 200, the colluding card portion 202 of breach 200 set up along the second direction for reagent card body 100 only need collude card mechanism 1 and just can realize the operation along first direction and second direction removal, compares in the current three direction that needs, has simplified operation action and process, has reduced manufacturing cost effectively. Meanwhile, the feeding portion 201 is used for feeding the card hooking mechanism 1, the card hooking mechanism 1 can enter the notch 200 initially, the card hooking portion 202 is used for hooking the card hooking mechanism 1, the feeding portion 201 is communicated with the card hooking portion 202, the card hooking mechanism 1 can slide into the card hooking portion 202 through the feeding portion 201, the feeding portion 201 and the card hooking portion 202 play a role in guiding the card hooking mechanism 1, the moving path of the card hooking mechanism 1 is limited, compared with the rectangular notch 200, the accommodating space of the notch 200 of the L-shaped structure is small, the limiting effect of the card hooking mechanism 1 is good, and the situation that the card hooking mechanism 1 moves in the notch 200 at will is avoided.
Further, as shown in fig. 3, a sample addition port 300 and an optical detection port 400 are disposed on the top surface of the reagent card body 100, the sample addition port 300 is used for adding a sample to the reagent card body 100 for incubation of the reagent card body 100, and the optical detection port 400 is used for detection of the reagent card body 100 for detecting performance indexes of the reagent card body 100.
In order to realize the detection of the performance index of the reagent card body 100, the embodiment provides a fluorescence immunoassay analyzer, as shown in fig. 3, the fluorescence immunoassay analyzer includes a rack 7, a housing 8 and an apparatus main body, the housing 8 is arranged on the rack 7, the rack 7 plays a role of integral support, the apparatus main body is arranged inside the housing 8, and the housing 8 plays a role of protecting the apparatus main body. The housing 8 is similar to a box structure of a rectangular parallelepiped, the width direction of the housing 8 is specifically the first direction, the length direction of the housing 8 is specifically the second direction, and the height direction of the housing 8 is the third direction.
As shown in fig. 4-5, the device main body includes a hooking mechanism 1, a sample feeding mechanism 2, a sample feeding mechanism 3 and an incubation mechanism 4, the sample feeding mechanism 2 is used for bearing a sample, the sample feeding mechanism 2 plays a role of supporting the sample, the sample feeding mechanism 3 is used for placing the sample in a sample feeding port 300 of the reagent card body 100, the hooking mechanism 1 is used for inserting a notch 200 of the reagent card body 100 and conveying the reagent card body 100 to the incubation mechanism 4, and the incubation mechanism 4 is used for incubating the reagent card body 100 with the sample.
The fluorescence immunoassay analyzer provided by this embodiment, after placing the sample on the sampling mechanism 2, the hooking mechanism 1 is used for inserting the notch 200 of the reagent card body 100 and conveying the same, the sample adding mechanism 3 is used for placing the sample in the sample adding port 300 of the reagent card body 100, the hooking mechanism 1 can be used for incubating the reagent card body 100 with the sample, and the incubation mechanism 4 is used for incubating the reagent card body 100 with the sample. Through the mutual cooperation of the sample feeding mechanism 2, the sample feeding mechanism 3, the incubation mechanism 4 and the card hooking mechanism 1, the operation process of the reagent card body 100 is continuous and gapless, and the production efficiency is high.
Optionally, the sample injection mechanism 2 may be a carrier, the carrier plays a role of bearing a sample, and an operator may place the sample on the carrier in sequence in a manual manner, preferably, a plurality of samples are sequentially stacked and placed on the carrier, so as to reduce the time for the operator to repeatedly load the sample, and the plurality of samples only occupy a space height, thereby saving the occupied space of the carrier.
Optionally, the sample adding mechanism 3 comprises a manipulator and a grabbing component, the output end of the manipulator is connected to the grabbing component, the grabbing component is used for grabbing the sample arranged on the carrying platform, and the manipulator can drive the grabbing component to move along the first direction, the second direction and the third direction respectively so as to complete the conveying of the sample. Preferably, the absorption subassembly includes vacuum generator and sucking disc, and vacuum generator communicates in the sucking disc, and vacuum generator can extract the air in the sucking disc for the sucking disc produces the negative pressure, adsorbs the sample, adopts this kind of mode, damages it when avoiding the sample centre gripping, with the roughness of guaranteeing the sample surface.
Optionally, as shown in fig. 5, the incubation mechanism 4 includes an incubation platform 41, a plurality of incubation cavities 411 are arranged on the incubation platform 41 at intervals in parallel along a second direction, each incubation cavity 411 corresponds to one incubation station 001, each incubation cavity 411 is used for accommodating and incubating one reagent card body 100, and the incubation cavities 411 are cavity structures and play a role in limiting the reagent card body 100. Incubation cavity 411 is one end open structure, and incubation cavity 411's opening orientation colludes card mechanism 1 setting for collude card mechanism 1 and can pass through opening propelling movement to incubation cavity 411 with reagent card body 100 in. The number of the incubation cavities 411 is preferably twelve in this embodiment, so that the incubation mechanism 4 can incubate twelve reagent card bodies 100 at the same time, and it can be understood that the incubation time needs to be matched with the time for feeding and discharging the reagent card bodies 100, so as to avoid the situation that the card hooking mechanism 1 waits for shutdown, and the production efficiency is high.
After the incubation of the reagent card body 100 is completed, in order to perform performance detection on the reagent card body, the fluorescence immunoassay analyzer further comprises a detection mechanism 6, wherein the detection mechanism 6 is arranged on the card hooking mechanism 1, and the detection mechanism 6 is used for detecting the incubated reagent card body 100. Optionally, the detection mechanism 6 is an optical detection module, and may specifically be a CCD camera or the like.
After reagent card body 100 accomplishes the detection, need withdraw from among the fluorescence immunoassay appearance, realize the circulation and detect, for this reason, still be provided with in one side of hatching platform 41 and move back the card chamber, move back card chamber and hatch chamber 411 parallel arrangement, move back the card chamber and be cavity structures, played reagent card body 100 spacing effect, move back the card chamber and correspond and move back card station 003. One side of the card withdrawing cavity close to the card withdrawing mechanism 1 is an inlet, one side of the card withdrawing cavity far away from the card withdrawing mechanism 1 is an outlet, when the card withdrawing mechanism 1 conveys the incubated reagent card body 100 to the inlet of the card withdrawing cavity, the card withdrawing mechanism 1 continues to push the reagent card body 100, so that the previous reagent card body 100 is ejected from the outlet of the card withdrawing cavity, at the moment, the reagent card body 100 is accommodated in the card withdrawing cavity, and the reagent card body 100 on the next side is ejected again.
The present embodiment further provides a card hooking mechanism 1 for conveying a reagent card structure, as shown in fig. 5-6, the card hooking mechanism 1 includes a first moving component 11, a card hooking component 12 and a second moving component 13, the first moving component 11 is connected to the card hooking component 12, and the first moving component 11 is configured to drive the card hooking component 12 to enter the feeding portion 201 of the reagent card body 100 along the first direction and to be in sliding fit therewith. The second moving assembly 13 is connected to the first moving assembly 11, and the second moving assembly 13 is configured to drive the first moving assembly 11 to drive the hook component 12 to move along the second direction into the hook portion 202 of the reagent card body 100 and to be in sliding fit with the hook portion 202, so that the first moving assembly 11 can drive the hook component 12 and the reagent card body 100 to move along the first direction.
The collude card mechanism 1 that this embodiment provided, first removal subassembly 11 drive colludes card subassembly 12 and moves along the first direction for collude card subassembly 12 and get into from breach 200 and feed in the portion 201, then second removal subassembly 13 drives through first removal subassembly 11 and colludes card subassembly 12 and get into colluding card portion 202 along the second direction, thereby realize colluding card subassembly 12 and collude the card body 100 of catching hold of reagent, after colluding, first removal subassembly 11 can drive and collude card subassembly 12 and drive reagent card body 100 and move along the first direction, in order to realize the transport of reagent card body 100. Because the moving direction of the first moving component 11 and the extending direction of the hooking part 202 are perpendicular to each other, the fixing effect between the hooking component 12 and the reagent card body 100 is good. Meanwhile, the hooking mechanism 1 only needs the first moving assembly 11 and the second moving assembly 13 to move in two directions, so that the production cost is saved, the layout is compact, the occupied area is small, and the space utilization rate is maximized.
Further, as shown in fig. 5 to 6, the first moving assembly 11 includes a first mounting plate 111, a first driving source 112, a first driving wheel 113, a first driven wheel (not shown), and a first conveyor belt 114, the first mounting plate 111 is disposed on the frame 7, the first driving source 112 is disposed on the first mounting plate 111, the first driving wheel 113 and the first driven wheel are rotatably disposed on the first mounting plate 111, and the first mounting plate 111 plays a role in mounting and fixing. The first driving source 112 is specifically a first motor, an output end of the first driving source 112 is connected to a first driving wheel 113, the first transmission belt 114 is respectively tensioned around the first driving wheel 113 and a first driven wheel and connected to the hook component 12, the first driving source 112 can drive the first driving wheel 113 to rotate, and drive the first driven wheel to rotate and the first transmission belt 114 and the hook component 12 to move, so that the rotary motion of the first driving source 112 is converted into linear motion of the first transmission belt 114, and the hook component 12 moves along the first direction.
Further, as shown in fig. 6, the hooking and fastening assembly 12 includes a hooking rod 121 and a first slider 122, the first slider 122 is connected to the first conveyor belt 114 and the hooking rod 121 of the first moving assembly 11, the first slider 122 plays a role of intermediate connection between the first conveyor belt 114 and the hooking rod 121, and the first slider 122 is preferably fixedly connected to the first conveyor belt 114 through a mounting seat, and drives the hooking rod 121 to move along the first direction as the first slider 122 moves along the first direction. The hook rod 121 is a rod-shaped structure, and since the notch 200 is disposed at the bottom of the reagent card body 100, the hook rod 121 is disposed along the vertical direction, that is, the hook rod 121 is disposed along the second direction, so that the hook rod 121 is directly inserted into the notch 200 disposed at the bottom of the reagent card body 100, and the hook rod 121 is conveniently inserted into the notch 200.
In order to ensure the moving direction of the first sliding block 122, a first guide rail 115 is disposed on the first mounting plate 111 along the first direction, and a first sliding groove is disposed on the first sliding block 122, and the first sliding groove is in sliding fit with the first guide rail 115, so that a guiding function is achieved, and the smoothness of the movement of the first sliding block 122 along the first direction is ensured.
Because the hook rod 121 when moving along first direction, hook rod 121 can strike reagent card body 100, make between hook rod 121 and the reagent card body 100 appear the rigidity collision and appear damaging, in order to solve this problem, this hook card subassembly 12 still includes connecting block 123, connecting rod 124 and reset piece 125, connecting block 123 is connected in hook rod 121, the one end of connecting rod 124 is connected in first slider 122, the other end wears to locate connecting block 123 and rather than sliding fit, connecting rod 124 has played the effect of first slider 122 and connecting block 123 intermediate junction. The reset element 125 is specifically a cylindrical spring, the reset element 125 is sleeved on the connecting rod 124, and two ends of the reset element 125 can respectively abut against the connecting block 123 and the first slider 122.
When the hook rod 121 strikes the reagent card body 100, the reagent card body 100 gives an impact force to the hook rod 121, the impact force enables the connecting block 123 to slide relative to the connecting rod 124 in a direction away from the hook rod 121, the connecting rod 124 plays a role in guiding the connecting block 123, the connecting block 123 gradually compresses the reset piece 125 in the process, the reset piece 125 positioned between the connecting block 123 and the first sliding block 122 plays a role in buffering, the impact force is offset, the phenomenon that the first motor is out of step due to striking is avoided, and the accuracy that the hook component 12 moves in the first direction is ensured.
It can be understood that the reagent card body 100 is a cuboid structure, the notch 200 is only arranged on one side of the reagent card body 100, if the hook rod 121 only hooks the notch 200 and drives the reagent card body 100 to move, although the reagent card body 100 can be moved, the reagent card can be inclined because of single-side bearing, in order to solve the problem, as shown in fig. 5-6, the hook mechanism 1 further comprises a limiting block 5, the limiting block 5 is arranged on the first mounting plate 111 of the first moving assembly 11, a limiting cavity 51 is arranged in the limiting block 5 along the first direction, the limiting cavity 51 is a cavity structure, the reagent card structure can be slidably fitted in the limiting cavity 51, and the limiting cavity 51 is used for limiting the reagent card structure.
By adopting the arrangement, under the driving action of the first moving component 11, the hook rod 121 is inserted into the notch 200 of the reagent card structure, and then the reagent card body 100 can be directly pulled into the limiting cavity 51, the limiting cavity 51 plays a role in accommodating the reagent card body 100, the top surface, the bottom surface and the two side surfaces of the limiting cavity 51 realize the limitation of the reagent card structure, and the situation of inclination when the reagent card structure moves along the first direction is avoided. Meanwhile, under the driving action of the second moving component 13, when the first moving component 11 and the reagent card structure move together along the second direction, the reagent card structure is always in the limiting cavity 51, so that the situation that the reagent card structure inclines when moving along the second direction is avoided.
Preferably, the hook rod 121 wears to locate spacing chamber 51 and rather than sliding fit, specifically, is provided with the through-hole in the bottom of stopper 5, and the through-hole sets up along the first direction, through-hole and spacing chamber 51 intercommunication, and hook rod 121 passes the through-hole and stretches into in the spacing chamber 51, and hook rod 121 can slide along the through-hole, and the through-hole has further injectd the moving direction of hook rod 121 when having played the guide effect.
It should be particularly noted that detection mechanism 6 is preferred to be set up on stopper 5, is provided with the via hole at stopper 5's top surface, and the via hole communicates in spacing chamber 51, and detection mechanism 6 and via hole are just to setting up, and detection mechanism 6 detects reagent card structure through crossing the pore pair, and spacing chamber 51 provides the required enclosure space of detection for reagent card structure this moment to guarantee the accuracy of detecting.
Further, as shown in fig. 5, the second moving assembly 13 includes a second mounting plate 131, a second driving source 132, a second driving wheel (not shown), a second driven wheel 133 and a second transmission belt 134, the second mounting plate 131 is disposed on the frame 7, the second driving source 132 is disposed on the frame 7, the second driving wheel and the second driven wheel 133 are rotatably disposed on the second mounting plate 131, and the second mounting plate 131 plays a role in mounting and fixing. The second driving source 132 is specifically a second motor, an output end of the second driving source 132 is connected to a second driving wheel, the second transmission belt 134 is respectively tensioned around the second driving wheel and the second driven wheel 133 and connected to the first mounting plate 111 of the first moving assembly 11, the second driving source 132 can drive the second driving wheel to rotate and drive the second driven wheel 133 to rotate and drive the second transmission belt 134 and the hook component 12 to move, so that the rotary motion of the second driving source 132 is converted into the linear motion of the second transmission belt 134, and the hook component 12 moves along the second direction.
In order to ensure the smoothness of the movement of the hooking and clamping component 12 along the second direction, a second guide rail 135 is arranged on the second mounting plate 131 along the second direction, a second slider is arranged at the bottom of the first mounting plate 111, and a guiding effect is achieved through the sliding fit of the second slider and the second guide rail 135, so that the smoothness of the movement of the first moving component 11 along the second direction is ensured. Preferably, a through hole is formed in the middle of the first mounting plate 111, and a guide rod is disposed on the second mounting plate 131 along the second direction, and the guide rod passes through the through hole and is in sliding fit with the through hole to perform a guiding function. Through the mutual cooperation of second guide rail 135 and the guide arm, play the dual direction of leading to about first mounting panel 111 to guarantee the smoothness nature of removal.
It can be understood that the pointed positions of the hook component 12 along the second direction are fifteen, including twelve incubation positions 001, one reagent card position 002, one card ejection position 003 and one zero position, the zero position is the initial position of the hook component 12, and the reagent card position 002 is the initial position of the reagent card.
When the sample injecting mechanism 2 starts to work, the hooking component 12 is located at a zero position, after a sample is placed on the sample injecting mechanism 2, under the driving action of the first moving component 11, the hooking mechanism 1 is inserted into the notch 200 of the reagent card body 100 and hooks the notch into the limiting cavity 51, the sample adding mechanism 3 is used for placing the sample in the sample adding port 300 of the reagent card body 100, under the driving action of the second moving component 13, the hooking mechanism 1 can convey the reagent card body 100 with the sample to the incubating mechanism 4, and the incubating station 001 of the incubating mechanism 4 is used for incubating the reagent card body 100 with the sample. After incubation is finished, the reagent card body 100 is hooked back to the limiting cavity 51, detection is carried out on the reagent card body by the detection mechanism 6, after detection is finished, the reagent card body 100 is conveyed to the card withdrawing station 003 by the card hooking mechanism 1, after the former reagent card body 100 serving as a waste card is pushed out of the rack 7, the card hooking mechanism 1 returns to a zero position, a cycle is finished, and next test is waited.
It should be particularly noted that, in order to ensure that the whole work cycle is performed orderly, a plurality of position sensors 9 are arranged on the rack 7, the position sensors 9 are specifically optical couplers, each position sensor 9 is used for detecting a fixed point position, when the hook and clamp assembly 12 triggers the position sensor 9 located at one fixed point position, the position sensor 9 transmits a position signal to the controller, the controller controls the next action to be started, each mechanism is tightly matched, and the production efficiency is high.
In the description herein, it is to be understood that the terms "upper", "lower", "right", and the like are based on the orientations and positional relationships shown in the drawings and are used for convenience in description and simplicity in operation, but do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed in a particular orientation, and be constructed in a particular operation, and thus should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used merely for descriptive purposes and are not intended to have any special meaning.
In the description herein, references to the description of "an embodiment," "an example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example.
In addition, the foregoing is only the preferred embodiment of the present invention and the technical principles applied. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Claims (10)
1. The utility model provides a reagent card structure, includes reagent card body (100), its characterized in that the bottom of reagent card body (100) is provided with breach (200), breach (200) are including feeding portion (201) and collude card portion (202), feeding portion (201) set up along the first direction, collude card portion (202) and set up along the second direction, feeding portion (201) with collude card portion (202) and communicate each other to form L shape structure, wherein the first direction with second direction mutually perpendicular.
2. The reagent card structure of claim 1, wherein a sample addition port (300) and an optical detection port (400) are provided on the reagent card body (100), the sample addition port (300) being used for adding a sample to the reagent card body (100), and the optical detection port (400) being used for detection of the reagent card body (100).
3. A catch mechanism for transporting a reagent card structure of any one of claims 1-2, the catch mechanism comprising:
a first moving assembly (11) and a hooking assembly (12), wherein the first moving assembly (11) is connected to the hooking assembly (12), and the first moving assembly (11) is configured to drive the hooking assembly (12) to enter the feeding part (201) of the reagent card body (100) along a first direction and to be in sliding fit with the feeding part;
the second moving assembly (13) is connected to the first moving assembly (11), the second moving assembly (13) is configured to drive the first moving assembly (11) to drive the hooking component (12) to move along a second direction into the hooking part (202) of the reagent card body (100) and to be in sliding fit with the hooking part, so that the first moving assembly (11) can drive the hooking component (12) and the reagent card body (100) to move along the first direction.
4. The card hooking mechanism according to claim 3, further comprising a limiting block (5), wherein the limiting block (5) is disposed on the first moving component (11), a limiting cavity (51) is disposed in the limiting block (5) along the first direction, the reagent card body (100) can be slidably fitted in the limiting cavity (51), and the limiting cavity (51) is used for limiting the reagent card body (100).
5. The hooking mechanism of claim 4, wherein the hooking member (12) comprises:
the hook rod (121) is inserted into the notch (200) of the reagent card body (100), and the hook rod (121) penetrates through the limiting cavity (51) and is in sliding fit with the limiting cavity;
a first slider (122) connected to the first moving assembly (11) and the hooking rod (121).
6. The hooking mechanism of claim 5, wherein the hooking member (12) further comprises:
a connecting block (123) connected to the hook bar (121);
one end of the connecting rod (124) is connected to the first sliding block (122), and the other end of the connecting rod (124) penetrates through the connecting block (123) and is in sliding fit with the connecting block;
and the resetting piece (125) is sleeved on the connecting rod (124), and two ends of the resetting piece (125) can be respectively abutted against the connecting block (123) and the first sliding block (122).
7. The hooking mechanism of claim 5, wherein the first moving assembly (11) comprises a first driving source (112), a first driving wheel (113), a first driven wheel and a first conveying belt (114), the first conveying belt (114) is respectively wound on the first driving wheel (113) and the first driven wheel and connected to the hooking assembly (12), an output end of the first driving source (112) is connected to the first driving wheel (113), and the first driving source (112) can drive the first driving wheel (113) to rotate and drive the first driven wheel to rotate and drive the first conveying belt (114) and the hooking assembly (12) to move.
8. The hooking and clamping mechanism as claimed in claim 5, wherein the second moving assembly (13) comprises a second driving source (132), a second driving wheel, a second driven wheel (133) and a second transmission belt (134), the second transmission belt (134) is respectively wound on the second driving wheel and the second driven wheel (133) in a tensioning manner and is connected to the first moving assembly (11), the output end of the second driving source (132) is connected to the second driving wheel, and the second driving source (132) can drive the second driving wheel to rotate and drive the second driven wheel (133) to rotate and the second transmission belt (134) and the hooking and clamping assembly (12) to move.
9. A fluorescence immunoassay analyzer, characterized by comprising a sample feeding mechanism (2), a sample feeding mechanism (3), an incubation mechanism (4) and the card hooking mechanism of any one of claims 3 to 8, wherein the sample feeding mechanism (2) is used for carrying a sample, the sample feeding mechanism (3) is used for placing the sample in a sample feeding port (300) of the reagent card body (100), the card hooking mechanism is used for inserting a notch (200) of the reagent card body (100) and conveying the reagent card body (100) to the incubation mechanism (4), and the incubation mechanism (4) is used for incubating the reagent card body (100) with the sample.
10. The fluoroimmunoassay analyzer of claim 9, further comprising a detection mechanism (6), wherein the detection mechanism (6) is disposed on the card hooking mechanism, and the detection mechanism (6) is used for detecting the reagent card body (100) after incubation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011504615.XA CN113341125A (en) | 2020-12-18 | 2020-12-18 | Reagent card structure, collude card mechanism and fluorescence immunoassay appearance |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011504615.XA CN113341125A (en) | 2020-12-18 | 2020-12-18 | Reagent card structure, collude card mechanism and fluorescence immunoassay appearance |
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| Publication Number | Publication Date |
|---|---|
| CN113341125A true CN113341125A (en) | 2021-09-03 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202011504615.XA Pending CN113341125A (en) | 2020-12-18 | 2020-12-18 | Reagent card structure, collude card mechanism and fluorescence immunoassay appearance |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114252598A (en) * | 2021-12-16 | 2022-03-29 | 广州万孚生物技术股份有限公司 | Card insertion device, fluorescence immunoassay instrument and control method of card insertion device |
| CN117405905A (en) * | 2023-12-15 | 2024-01-16 | 广州誉康医药有限公司 | Reagent card selecting system |
-
2020
- 2020-12-18 CN CN202011504615.XA patent/CN113341125A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114252598A (en) * | 2021-12-16 | 2022-03-29 | 广州万孚生物技术股份有限公司 | Card insertion device, fluorescence immunoassay instrument and control method of card insertion device |
| CN117405905A (en) * | 2023-12-15 | 2024-01-16 | 广州誉康医药有限公司 | Reagent card selecting system |
| CN117405905B (en) * | 2023-12-15 | 2024-02-20 | 广州誉康医药有限公司 | Reagent card selecting system |
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