CN113332292A - 6,7-二氢-5H-吡唑并[5,1-b][1,3]噁嗪-2-甲酰胺化合物 - Google Patents

6,7-二氢-5H-吡唑并[5,1-b][1,3]噁嗪-2-甲酰胺化合物 Download PDF

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Publication number
CN113332292A
CN113332292A CN202110445183.8A CN202110445183A CN113332292A CN 113332292 A CN113332292 A CN 113332292A CN 202110445183 A CN202110445183 A CN 202110445183A CN 113332292 A CN113332292 A CN 113332292A
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China
Prior art keywords
pyrazolo
dihydro
oxazine
cyclopropyl
carboxamide
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Pending
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CN202110445183.8A
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Chinese (zh)
Inventor
T·A·查皮
N·C·帕特尔
P·R·维尔赫斯特
C·J·赫拉尔
S·夏波拉
E·A·拉查佩尔
T·T·瓦格
M·M·海沃德
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Pfizer Inc
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Pfizer Inc
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Publication of CN113332292A publication Critical patent/CN113332292A/zh
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CN202110445183.8A 2016-02-23 2017-02-15 6,7-二氢-5H-吡唑并[5,1-b][1,3]噁嗪-2-甲酰胺化合物 Pending CN113332292A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662298657P 2016-02-23 2016-02-23
US62/298657 2016-02-23
CN201780013020.4A CN108699080B (zh) 2016-02-23 2017-02-15 6,7-二氢-5H-吡唑并[5,1-b][1,3]噁嗪-2-甲酰胺化合物

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CN113332292A true CN113332292A (zh) 2021-09-03

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CN201780013020.4A Active CN108699080B (zh) 2016-02-23 2017-02-15 6,7-二氢-5H-吡唑并[5,1-b][1,3]噁嗪-2-甲酰胺化合物

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US (2) US10323042B2 (https=)
EP (1) EP3419979B1 (https=)
JP (1) JP6837072B2 (https=)
KR (1) KR102148587B1 (https=)
CN (2) CN113332292A (https=)
AU (1) AU2017223132B2 (https=)
BR (1) BR112018015191B1 (https=)
CA (1) CA3015166C (https=)
DK (1) DK3419979T3 (https=)
ES (1) ES2775674T3 (https=)
HU (1) HUE048658T2 (https=)
IL (1) IL260536B (https=)
MX (1) MX379704B (https=)
PL (1) PL3419979T3 (https=)
PT (1) PT3419979T (https=)
RU (1) RU2719599C2 (https=)
SG (1) SG11201806383TA (https=)
WO (1) WO2017145013A1 (https=)
ZA (1) ZA201804619B (https=)

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