CN113316578A - 杂环化合物、包含其的药物组合物及其制备方法和用途 - Google Patents
杂环化合物、包含其的药物组合物及其制备方法和用途 Download PDFInfo
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- CN113316578A CN113316578A CN202080009954.2A CN202080009954A CN113316578A CN 113316578 A CN113316578 A CN 113316578A CN 202080009954 A CN202080009954 A CN 202080009954A CN 113316578 A CN113316578 A CN 113316578A
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- alkoxy
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- 125000000623 heterocyclic group Chemical group 0.000 claims description 196
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 10
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- 125000000714 pyrimidinyl group Chemical group 0.000 claims description 5
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- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical group C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 claims description 2
- 208000015634 Rectal Neoplasms Diseases 0.000 claims description 2
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- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 1
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Abstract
本发明涉及杂环化合物、包含其的药物组合物及其制备方法和用途。具体而言,本发明的化合物由式(I)表示,其用于预防或治疗与RET活性相关的疾病或病况。
Description
PCT国内申请,说明书已公开。
Claims (12)
- PCT国内申请,权利要求书已公开。
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202311264080.7A CN117327078A (zh) | 2019-02-19 | 2020-02-11 | 杂环化合物、包含其的药物组合物及其制备方法和用途 |
CN202311221283.8A CN117263945A (zh) | 2019-02-19 | 2020-02-11 | 杂环化合物、包含其的药物组合物及其制备方法和用途 |
Applications Claiming Priority (7)
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CN2019101245846 | 2019-02-19 | ||
CN201910124584 | 2019-02-19 | ||
CN201910437878 | 2019-05-24 | ||
CN2019104378784 | 2019-05-24 | ||
CN2019109320953 | 2019-09-29 | ||
CN201910932095 | 2019-09-29 | ||
PCT/CN2020/074696 WO2020168939A1 (zh) | 2019-02-19 | 2020-02-11 | 杂环化合物、包含其的药物组合物及其制备方法和用途 |
Related Child Applications (2)
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CN202311264080.7A Division CN117327078A (zh) | 2019-02-19 | 2020-02-11 | 杂环化合物、包含其的药物组合物及其制备方法和用途 |
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CN103298788A (zh) * | 2010-10-28 | 2013-09-11 | 日本新药株式会社 | 吡啶衍生物及医药 |
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JP2013107824A (ja) * | 2010-03-17 | 2013-06-06 | Dainippon Sumitomo Pharma Co Ltd | 新規単環ピリミジン誘導体 |
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CN117263945A (zh) | 2023-12-22 |
CL2021002205A1 (es) | 2022-04-22 |
US20220144847A1 (en) | 2022-05-12 |
IL285378A (en) | 2021-09-30 |
CO2021011023A2 (es) | 2021-09-09 |
WO2020168939A1 (zh) | 2020-08-27 |
CN117327078A (zh) | 2024-01-02 |
SG11202107848TA (en) | 2021-08-30 |
EP3929198A1 (en) | 2021-12-29 |
MX2021009971A (es) | 2021-10-13 |
BR112021016299A2 (pt) | 2021-10-13 |
KR20210131314A (ko) | 2021-11-02 |
CN113316578B (zh) | 2023-10-31 |
EP3929198A4 (en) | 2022-11-16 |
JP2022521859A (ja) | 2022-04-12 |
CA3130245A1 (en) | 2020-08-27 |
AU2020226422A1 (en) | 2021-09-09 |
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