CN113288995A - Traditional Chinese medicine enema prescription composition for treating intestinal obstruction - Google Patents
Traditional Chinese medicine enema prescription composition for treating intestinal obstruction Download PDFInfo
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- CN113288995A CN113288995A CN202110608461.7A CN202110608461A CN113288995A CN 113288995 A CN113288995 A CN 113288995A CN 202110608461 A CN202110608461 A CN 202110608461A CN 113288995 A CN113288995 A CN 113288995A
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- enema
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Abstract
The invention discloses a medicine composition of a traditional Chinese medicine enema prescription for treating intestinal obstruction, which is characterized in that: The traditional Chinese medicine enema prescription is a combination of traditional Chinese medicine. The traditional Chinese medicine is composed of Cinnamon sticks, white peony root, ginger, jujube, licorice, astragalus, Radix serrata, Chinese yam, raw rehmannia, Ophiopogon japonicus, Scrophulariaceae, Magnolia officinalis, Fructus Aurantii, Rhubarb and Scutellaria, and the formula ratio is 9:18:6:10:6:18:18:18:15:15:15:15:15:15:18; the using method comprises the following steps: use a traditional Chinese medicine prescription, decoct each dose to 200ml×2 bags, each patient uses 1 bag a day, the temperature is 37~40℃, use the enema bag to slowly enema the medicine, the enema time is about 10 minutes, and instruct the patient to contract the anus as much as possible after enema and hold back for 10-15 minutes before defecation. The invention applies the Chinese medicine prescription water decoction to treat the intestinal obstruction, and by taking advantage of the characteristics of the traditional Chinese medicine enema to replenish qi and nourish yin, and to replenish and reduce the effect, it not only avoids the cold and cold of Chengqi formulas, aggravates the loss of Qi and Yin, but also prevents the patient from deficiency of both Qi and Yin, deficiency and no supplementation, overuse of tonic drugs to reduce dampness and phlegm, and aggravate the obstruction, and the clinical treatment effect is obvious.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicine prescriptions, in particular to a traditional Chinese medicine enema prescription for treating intestinal obstruction.
Background
At present, the mainstream view of selecting a traditional Chinese medicine enema prescription for intestinal obstruction in China mostly adopts a cold and cool drastic treatment principle, the enema is performed by selecting qi-supporting decoction preparations according to a method of qi-breaking and purgation aiming at symptoms such as stopping exhausting and defecation of anus, the pathogenesis of the intestinal obstruction is known, the intestinal obstruction is comprehensively analyzed from the angle of combination of syndrome factors and symptoms, the intestinal obstruction is considered not to be a local disease but a systemic disease, and the imbalance of qi and yin and yang is presented by the symptoms of improper diet, emotional distress, qi and blood stasis, damp pathogen obstruction, heat evil obstruction, cold accumulation of intestines, abdominal operation and the like due to the action of various pathogenic factors, so that the organism loses the symptoms of qi and yin deficiency and yin and yang, and viscera are disordered in the acute stage of the intestinal obstruction, the dysfunction, the transportation and transformation weakness, qi and the generation and distribution of qi and body fluid are caused by the imbalance of qi and the imbalance of viscera and the qi and the moistening and yin of human body, deficiency of both qi and yin causes insufficient qi and blood source, blood circulation is unfavorable to cause blood stasis, the blood stasis is caused by being combined in six fu-organs and can not be transferred and transformed, qi of the fu-organs is obstructed, the normal operation of qi activity is damaged, the lifting function of the fu-organs is disordered, abdominal distension and abdominal pain even the phenomenon of exhaust and defecation stop occur, and partial chronic intestinal obstruction patients have the basic pathogenesis of deficiency of qi and yin and imbalance of yin and qi, and the disease aggravation risk is caused if the acute or chronic intestinal obstruction is treated by taking cold and drastic prescription.
Disclosure of Invention
The invention aims to overcome the problems in the prior art, provides a traditional Chinese medicine enema prescription for treating intestinal obstruction, is different from the inherent mode of treating intestinal obstruction by relieving qi and eliminating qi, abandons the drastic cold and cool usage of large qi-bearing decoction and the like, adopts the medication ideas of supplementing qi and nourishing yin and harmonizing yin and yang from the basic symptoms and features of patients, applies the qi-bearing and yin-bearing medicine prescription enema to treat intestinal obstruction, has the characteristics of tonifying and purgation, avoids the severe cold and cool of qi-bearing formulas, aggravates the consumption of qi and yin of patients, prevents the deficiency of both qi and yin of patients, prevents deficiency from not being compensated, and uses tonifying medicines to resolve dampness and generate phlegm to aggravate the obstruction, and clinical data shows that the medicine prescription has good treatment effect.
In order to achieve the technical purpose and achieve the technical effect, the invention is realized by the following technical scheme:
a traditional Chinese medicine enema prescription for treating intestinal obstruction is composed of a traditional Chinese medicine prescription composed of cassia twig, white paeony root, ginger, Chinese date, liquorice, astragalus, radix pseudostellariae, Chinese yam, radix rehmanniae, radix ophiopogonis, radix scrophulariae, mangnolia officinalis, fructus aurantii, rheum officinale and semen raphani, and the prescription ratio is 9:18:6:10:6:18:18: 15:15:15:15:15: 18; the using method comprises the following steps: the method comprises the steps of using a traditional Chinese medicine formula (9 g of cassia twig, 18g of white paeony root, 6g of ginger, 10g of Chinese date, 6g of honey-fried licorice root, 18g of astragalus root, 18g of radix pseudostellariae, 18g of Chinese yam, 15g of dried rehmannia root, 15g of radix ophiopogonis, 15g of figwort root, 15g of mangnolia officinalis, 15g of fructus aurantii, 15g of rheum officinale and 18g of semen raphani), decocting each dose to 200ml multiplied by 2 bags, using 1 bag per patient each day, using the temperature of 37-40 ℃ to use, slowly enema the liquid medicine by using an enema bag, enabling the enema time to be about 10min, and enabling the patient to contract the anus to be blocked for 10-15min after enema is performed.
Compared with the prior art, the invention has the following beneficial effects: by distinguishing from the inherent mode of treating intestinal obstruction by breaking qi and attacking the lower, the use of big qi-bearing decoction and other cold and cool and drastic uses is abandoned, the medication ideas of tonifying qi and nourishing yin and harmonizing yin and yang are adopted from the characteristics of basic symptoms of patients, the enema method for tonifying qi and nourishing yin is applied to treat intestinal obstruction, the characteristics of both tonifying and purging are kept by the qi-tonifying and yin-nourishing method, the enema method not only avoids the serious cold and cool condition of qi-bearing formulas to aggravate the consumption of qi and yin of the patients, but also prevents the deficiency of both qi and yin of the patients from being compensated, the dampness and phlegm are dissolved by using tonifying medicaments to aggravate the obstruction condition, and simultaneously the qi-tonifying and yin-nourishing method has the multiple effects of promoting gastrointestinal motility, protecting intestinal tracts, resisting infection and the like besides relaxing bowels, the intestinal barrier function is protected in the process of treating intestinal obstruction, the recovery speed of intestinal obstruction is accelerated, the general symptoms of the patients are improved, and the recurrence frequency of intestinal obstruction is obviously reduced, has good treatment effect.
Of course, it is not necessary for any product in which the invention is practiced to achieve all of the above-described advantages at the same time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic graph comparing the treatment effect of two groups of patients according to the present invention;
FIG. 2 is a schematic graph of the therapeutic effect of two groups of patients according to the present invention after treatment;
FIG. 3 is a sector statistical chart showing the efficiency of the Chinese medicinal enema set of the present invention;
FIG. 4 is a graph of sector statistics for the control group efficiency of the present invention;
FIG. 5 is a bar chart comparing two sets of exhaust and bowel movement recovery times according to the present invention;
FIG. 6 is a bar graph comparing the number of days of antibiotic use for two groups of the present invention;
FIG. 7 is a bar chart comparing the upgrade of two groups of antibiotics of the present invention;
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-7, a traditional Chinese medicine enema prescription for treating intestinal obstruction is shown, and the traditional Chinese medicine enema prescription is a traditional Chinese medicine prescription which is composed of cassia twig, white paeony root, ginger, Chinese date, liquorice, astragalus, radix pseudostellariae, Chinese yam, radix rehmanniae, radix ophiopogonis, radix scrophulariae, mangnolia officinalis, fructus aurantii, rheum officinale and semen raphani, and the prescription ratio is 9:18:6: 18:18:15:15:15:15:15: 18; the using method comprises the following steps: the method comprises the steps of using a traditional Chinese medicine formula (9 g of cassia twig, 18g of white paeony root, 6g of ginger, 10g of Chinese date, 6g of honey-fried licorice root, 18g of astragalus root, 18g of radix pseudostellariae, 18g of Chinese yam, 15g of dried rehmannia root, 15g of radix ophiopogonis, 15g of figwort root, 15g of mangnolia officinalis, 15g of fructus aurantii, 15g of rheum officinale and 18g of semen raphani), decocting each dose to 200ml multiplied by 2 bags, using 1 bag per patient each day, using the temperature of 37-40 ℃ to use, slowly enema the liquid medicine by using an enema bag, enabling the enema time to be about 10min, and enabling the patient to contract the anus to be blocked for 10-15min after enema is performed.
Example (b):
the enema is characterized in that a patient is decocted to 200ml × 2 bags per dose, each patient uses 1 bag per day, the temperature during use is 37-40 ℃, the liquid medicine is slowly enema by using an enema bag, the enema time is about 10min, the patient is advised to contract the anus as much as possible after enema for 10-15min and then defecate, so that the use method of cold and cool drastic treatment such as Dachengqi decoction is abandoned by distinguishing the inherent mode of treating intestinal obstruction by qi breaking and attacking in the current traditional Chinese medicine, the medication thought of tonifying qi and nourishing yin and harmonizing yin and yang is adopted from the characteristics of the basic symptoms of the patient, the qi-tonifying and yin-nourishing prescription medicine enema is used for treating intestinal obstruction, and ginger processed pinellia tuber, raw coix seed, amomum cardamomum, lophatherum gracile and talcum powder are additionally added when the patient has damp-heat symptoms; radix astragali can be added for patients with severe qi deficiency; radix Ophiopogonis and radix rehmanniae Preparata can be added for patients with severe yin deficiency; semen Armeniacae amarum may be added for patients with dry stool; therefore, the retention enema has the characteristics of tonifying and purging by the qi-tonifying and yin-nourishing formula, so that the phenomenon that the qi-bearing formula is cold, cool and drastic, aggravates the consumption of qi and yin of a patient is avoided, the phenomenon that the deficiency of both qi and yin of the patient is not supplemented, and the obstruction is aggravated by dampness and phlegm generation through using tonifying medicines is prevented;
from the pharmacological perspective of traditional Chinese medicines, the cassia twig volatile oil has good comprehensive pharmacological activities such as anti-inflammation and immunity, the anti-inflammation effect is obviously enhanced after the radix paeoniae alba and the cassia twig are matched, and the radix paeoniae alba and the cassia twig have synergistic effect; astragalus polysaccharide can regulate a Toll-like receptor 4/nuclear factor-kB (NF-kB) signal transduction path to reduce the contents of inflammatory mediators interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), prostaglandin E2 and the like, so that an anti-inflammatory effect is exerted, and rhein anthrone decomposed after the daidzin enters an intestinal tract can stimulate the intestinal mucosa, so that intestinal tract peristalsis is caused, and defecation is promoted; the mangnolia officinalis can play a role in promoting gastric emptying and intestinal propulsion by antagonizing oxidative stress and regulating Cajal cells; volatile oil and flavonoid in fructus aurantii have the effects of promoting gastric motility and accelerating intestinal peristalsis, and radix pseudostellariae polysaccharide and ophiopogonpolysaccharide also have the effect of protecting intestinal tracts, so that the qi-tonifying and yin-nourishing enema formula has multiple effects of promoting gastrointestinal peristalsis, protecting intestinal tracts, resisting infection and the like besides relaxing bowels, protects the function of an intestinal tract barrier in the process of treating intestinal obstruction, accelerates the recovery speed of intestinal obstruction, improves the general symptoms of patients, obviously reduces the recurrence frequency of intestinal obstruction, and has good treatment effect, and the method specifically comprises the following steps:
the traditional Chinese medicine formula for treating intestinal obstruction can obviously shorten the time for recovering air exhaust and defecation of patients:
from the clinical point of view, the cessation of air and defecation is the result of the onset of intestinal obstruction and the most important cause of the continuous aggravation of intestinal obstruction;
from the perspective of traditional Chinese medicine, the stopping of evacuation and defecation is mainly caused by the dysfunction of the ascending and descending of the intestines and the stagnation of qi, which causes the unsmooth circulation of qi and blood, imbalance of yin and yang, consumption of qi and yin, lack of nourishment of the viscera, dysfunction, weakness in pushing and obstruction of qi of the viscera, and the stopping of evacuation and defecation; if the ventilation is not resumed in time, the qi stagnation is aggravated by long-term stoppage, and further qi and yin are damaged to form a vicious circle. Therefore, on the basis of the pathology that the qi obstruction of the large intestine and the consumption of qi and yin of the large intestine of the patient with intestinal obstruction are causality mutually, when the treatment is carried out, the large intestine is cleared and the qi is exhausted, the qi is supplemented and the yin is nourished, and the good treatment effect can be achieved only if the large intestine is cleared and the qi is exhausted, and the qi and the yin are supplemented mutually. The traditional Chinese medicine formula follows the medication idea, uses the preparation for tonifying qi and nourishing yin and purgation and promoting the circulation of the interior, strengthens the body resistance and eliminates evil, has the characteristic of both reinforcing and purging, not only avoids the phenomenon that the qi-bearing formula is cold and cool and strong, aggravates the consumption of qi and yin of a patient, but also prevents the phenomenon that the qi and yin of the patient are deficient and the deficiency is not compensated, and the obstruction is aggravated by using tonifying medicines to eliminate dampness and generate phlegm, and has obvious curative effect;
from the perspective of western medicine, anus blockage caused by intestinal obstruction is mainly caused by intestinal cavity effusion and intestinal canal expansion caused by operations, external force trauma, adhesion, foreign bodies, fecalities, tumors and the like, so that the intestinal canal is expanded and the pressure is increased; the intestinal lumen releases anti-absorption hormone and paracrine substances, which increases intestinal mucosal epithelial secretion and inhibits fluid absorption, while releasing prostaglandin to aggravate fluid accumulation; the intestinal cavity is lack of oxygen, the intestinal bacteria breed in large quantity under the condition of oxygen deficiency, the gas and liquid are aggravated, the intestinal canal expands and the intestinal pressure increases to block the venous reflux of the intestinal wall, and the blood stasis of the capillary vessel and the lymphatic vessel causes the congestion and edema of the intestinal wall, the permeability is increased, the liquid is exosmosed, and the vicious circle is formed. Therefore, the timely recovery of the patient's defecation and urination is the most important factor for treating intestinal obstruction, and has important significance for the healing of intestinal obstruction, and the rhubarb, the immature bitter orange, the magnolia bark and other substances can discharge intestinal dregs and promote the source of transformation, open various toxin discharge pipelines, discharge toxins in the body, pass through twelve meridians, enhance the metabolism of the organism, make qi and blood smooth, and ensure the functional activities of viscera to be normal. Modern researches also show that the materials such as the white paeony root, the cassia twig, the astragalus and the like have the effects of resisting bacteria and inflammation and can prevent the mass propagation of intestinal bacteria to inhibit the vicious circle;
therefore, the traditional Chinese medicine formula enema formula taking qi tonifying and yin nourishing as the main medication thought has good theoretical basis from the theoretical aspect; practically speaking, the retrospective example control study made by us shows that the enema treatment of ileus by the traditional Chinese medicine prescription can remarkably shorten the time (P < 0.05) for patients to recover from air and defecate. The enema with the traditional Chinese medicine prescription can remarkably accelerate the recovery efficiency of intestinal obstruction, has important clinical significance and is worthy of application and popularization;
the enema treatment of intestinal obstruction with the traditional Chinese medicine prescription can obviously shorten the use time of antibiotics and improve the upgrade condition of the antibiotics
Anti-infective therapy is an important component of the conventional treatment of ileus. Drugs such as cephalosporin, levoornidazole and the like are commonly applied clinically to resist infection, which is an essential link in the treatment process of intestinal obstruction, and mainly because pathological changes such as intestinal barrier function damage, mucosal permeability increase, homeostasis break and flora shift (BT) and the like often occur in the pathogenesis process of intestinal obstruction, so that the microecological balance of flora in vivo is broken, if antibiotics are not timely applied, the intestinal mucosal barrier function is further influenced to aggravate intestinal obstruction, even multiple organ dysfunction is caused, and meanwhile, the flora shift and the intestinal barrier damage are mutually causal to cause vicious circle. In addition, studies have shown that C-reactive protein and interleukin-6 (IL-6) are important substances involved in inflammatory response of sexual ileus, and can excite sympathetic nerves, inhibit vagus nerves, and cause obstruction due to intestinal wall edema, exudation, and intestinal stenosis, so that it is necessary to control the inflammatory response in time to prevent further aggravation of ileus. Therefore, in the process of treating intestinal obstruction, the application of antibiotics is indispensable, and the antibiotics can improve the level of inflammation, promote the disappearance of the inflammation and prevent adverse consequences caused by the occurrence of flora shift. However, although antibiotics are used for preventing and treating infection caused by flora shift in the treatment process, the effect is unsatisfactory, and long-term application of antibiotics is easy to cause drug resistance of a large number of intestinal flora, so that the treatment difficulty is increased, and a large burden is caused to the economy of patients;
therefore, reducing the number of days of antibiotic use during treatment is particularly important for the recovery of ileus; research shows that the traditional Chinese medicine can effectively maintain the stability of intestinal micro-ecosystem and directly or indirectly regulate the imbalance of intestinal flora. The direct regulation is to change the composition and the quantity of flora in the intestinal tract, and the indirect regulation is to maintain the balance of intestinal micro-ecology by protecting the barrier function of intestinal mucosa and preventing the flora from shifting, thereby accelerating the recovery of intestinal obstruction. Meanwhile, the method of supplementing qi and nourishing yin may also have the function of strengthening the healthy energy of the human body, namely, the principle of strengthening the healthy energy and eliminating evil explained in the traditional Chinese medicine is applied to improve the resistance of the organism and accelerate the recovery of the organism. The retrospective disease case comparison research results also further prove that the number of days for using antibiotics (P is less than 0.05) can be obviously shortened by matching the qi-tonifying yin-nourishing enema formula in the conventional treatment, the antibiotic upgrading condition (P is less than 0.05) in the treatment process is reduced, and the application prospect is wide;
clinical statistics show that the effective rate of the enema group (traditional Chinese medicine enema group) applying the traditional Chinese medicine formula is obviously higher than that of the conventional western medicine enema group (control group) (P < 0.05) (see figure 1, figure 3 and figure 4 in the attached drawing of the specification), the time (P < 0.05) for patients to recover from exsufflation and defecation can be obviously shortened (see figure 2 and figure 5 in the attached drawing of the specification), the number of days (P < 0.05) for antibiotics can be obviously shortened (see figure 2 and figure 6 in the attached drawing of the specification), and the upgrading condition (P < 0.05) of antibiotics in the treatment process can be reduced (see figure 2 and figure 7 in the attached drawing of the specification).
In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.
Claims (1)
1. The composition of a traditional Chinese medicine enema prescription for treating intestinal obstruction is characterized in that: the traditional Chinese medicine enema prescription is a traditional Chinese medicine prescription which is composed of cassia twig, white paeony root, ginger, Chinese date, liquorice, astragalus mongholicus, radix pseudostellariae, Chinese yam, radix rehmanniae, radix ophiopogonis, radix scrophulariae, mangnolia officinalis, fructus aurantii, rheum officinale and semen raphani, and the prescription ratio is 9:18:6:10:6:18:18:18:15:15:15:15: 18; the using method comprises the following steps: the method comprises the steps of using a traditional Chinese medicine formula (9 g of cassia twig, 18g of white paeony root, 6g of ginger, 10g of Chinese date, 6g of honey-fried licorice root, 18g of astragalus root, 18g of radix pseudostellariae, 18g of Chinese yam, 15g of dried rehmannia root, 15g of radix ophiopogonis, 15g of figwort root, 15g of mangnolia officinalis, 15g of fructus aurantii, 15g of rheum officinale and 18g of semen raphani), decocting each dose to 200ml multiplied by 2 bags, using 1 bag per patient each day, using the temperature of 37-40 ℃ to use, slowly enema the liquid medicine by using an enema bag, enabling the enema time to be about 10min, and enabling the patient to contract the anus to be blocked for 10-15min after enema is performed.
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