CN108686197A - A kind of Chinese medicine composition that treating gastritis and its application - Google Patents

A kind of Chinese medicine composition that treating gastritis and its application Download PDF

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CN108686197A
CN108686197A CN201810991894.3A CN201810991894A CN108686197A CN 108686197 A CN108686197 A CN 108686197A CN 201810991894 A CN201810991894 A CN 201810991894A CN 108686197 A CN108686197 A CN 108686197A
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grams
peel
gastritis
chinese medicine
stomach
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刘仲永
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Guizhou Arcadia Medical Management Co Ltd
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Guizhou Arcadia Medical Management Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285Aucklandia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Abstract

The present invention relates to a kind of Chinese medicine compositions for treating gastritis, are made of bulk pharmaceutical chemicals such as Cortex Magnoliae Officinalis, Fructus Aurantii, green peel, dried orange peel, root of Aucklandia lappa Decne, the shell of areca nut, umbellate pore furgus, rhizoma alismatis, Poria cocos, akebi, ginger peel, Radix Codonopsis, motherwort, Radix Angelicae Sinensis, safflower, Stephania tetrandra, cassia twig and stone reeds.Wherein Cortex Magnoliae Officinalis, Fructus Aurantii, the shell of areca nut, umbellate pore furgus, rhizoma alismatis, akebi and root of Aucklandia lappa Decne expel the heat-evil clear stagnant, adjust stomach movement, Radix Codonopsis, dried orange peel regulating qi-flowing for harmonizing stomach, strengthening spleen and tonifying lung;Be aided with green peel, cassia twig relieves pain soothing the liver relieving stagnant Qi, mitigates abdominal distention, motherwort is clearing heat and detoxicating;Promoting blood circulation and removing blood stasis with safflower simultaneously, Chinese angelica blood supplementing promoting blood circulation fully improves the blood circulation of gastric mucosa, increases gastric mucosa blood supply, and recession inflammatory lesions promote gastric mucosal cell regeneration and injury tissue reparation.Dried orange peel mainly plays promoting digestion effect, all medicines share, the effect of can playing invigorating the spleen, analgesic, dispersing stagnated hepatoqi well, and mutual compatibility between each drug, warming middle-JIAO and strengthening the spleen, dispersing stagnated hepatoqi and stomach and alleviating pain soothing the liver reach therapeutic effect together.

Description

A kind of Chinese medicine composition that treating gastritis and its application
Technical field
The invention belongs to technical field of traditional Chinese medicines, it is related to a kind of Chinese medicine composition that treating gastritis and its application.
Background technology
Chronic gastritis is alimentary canal common disease, frequently-occurring disease, and chronic gastritis is the chronic inflammatory reaction of stomach lining, most chronic Gastritis sufferer can have symptom to be mainly shown as that non-specific digestion is bad without apparent clinical symptoms, and such as epigastric discomfort is satisfied Can also there be the psychic symptoms such as forgetful, anxiety, depression in swollen, pain, loss of appetite, belch, sour regurgitation etc., part.With canker It is opposite pleasant on an empty stomach, it is uncomfortable after meal, it may seldom feel satiety though feeding because of diastolic dysfunction of holding.Patient is normal It tells " stomach is weak " or " stomach is soft ".Often because cold food, hard food, pungent or other irritable foods cause symptom or make exacerbation of symptoms.These Symptom antacids and antispasmodic are not easy to alleviate.In addition, bleeding is also one of symptom of chronic gastritis, especially merge rotten to the corn. Male is more than women in patient, and increasing incidence with the age gradually increases.
Chronic gastritis is divided into superficial gastritis, atrophic gastritis, hypertrophic gastritis etc. according to mucosa tissue variation, The Etiological of chronic gastritis is caused to be that Hp infects, a variety of inflammatory mediators and toxicant intervene its course of infection, cause thin There is gastric mucosal erosion, ulcer, bleeding etc. in born of the same parents' autoimmune response.The essence of chronic gastritis is gastric epithelial by repeatedly After damage, due to the special power of regeneration of mucous membrane, so that mucous membrane is reconstructed, and irreversible intrinsic stomach glands are eventually led to Atrophy, or even disappear.The treatment side of Pantoprazole+amoxicillin and clavulanate potassium+clarithromycin is applied in Conventional treatment regimens Case carrys out gastric acid secretion inhibiting, kills Hp, symptom can be effectively relieved, but easily cause drug resistance and adverse reaction when long-term administration, So that inflammation wholistic therapy is not thorough.Chinese medicine carries out differentiation of symptoms and signs for classification of syndrome according to its Clinical symptoms, and chronic gastritis is included in " epigastric pain " " indigestion and loss of appetite " " feeling of fullness " etc., and think overstrain, diet, feelings will damage etc. cause liver-stomach disharmony, ascending or descending movement of vital Qi imbalance, retention of phlegmatic dampness, The dysfunction of the spleen in transport, the stomach network stasis of blood stagnant etc. are its interpretation of the cause, onset and process of an illness of falling ill.
Stomach physiologically with be reduced to suitable, pathologically because stagnant and sick, chronic gastritis is mainly lost with weakness of the spleen and the stomach, feelings will The many factors such as tune, eating and drinking without temperance, drug, exopathogen (helicobacter pylori infections) are related, above-mentioned factor impairing the spleen and stomach, and transporting is caused to lose Department, disturbance in ascending and descending, and the stagnation of the circulation of vital energy, dampness, cold solidifying, fiery strongly fragrant, blood stasis occurs etc., show as the symptoms such as stomachache, turgor.Chronic gastritis The interpretation of the cause, onset and process of an illness can be divided into this void and real two aspects of mark.This void is mainly shown as that temper (sun) is empty and stomach-Yin deficiency, mark are mainly shown as in fact The stagnation of the circulation of vital energy, damp and hot and blood stasis, spleen deficiency, the stagnation of the circulation of vital energy are the basic pathogenesis of disease.Blood stasis is the important pathogenesis of prolonged illness, is sent out in Mucosal atrophy It plays an important role during hair tonic exhibition or even canceration.Clinically often show as asthenia in origin and asthenia in superficiality, simulataneous insufficiency and excessive card.In early days Based on real example, disease then becomes asthenic symptoms or simulataneous insufficiency and excessive long;Early stage, disease is then simultaneous long to relate to blood system mostly in qi leel.Chronic non-atrophic For gastritis with weakness of the spleen and the stomach, syndrome of incoordination between liver and stomach is common;For atrophic gastritis with weakness of the spleen and the stomach, syndrome of qi stagnation and blood stasis is common;Chronic stomach It is scorching common with syndrome of incoordination between liver and stomach with bile regurgitation;Accompanied with Helicobacter pylori infection is common with syndrome of dampness-heat of spleen and stomach;With precancerous lesion person with Deficiency of both qi and yin, qi depression to blood stasis, damp-heat blocking in the body card are common.
Currently, treatment chronic gastritis method mainly based on western medical treatment, mainly take gastric acid secretion inhibiting, in Treated with the drug and antibiosis anti-inflammatory drug of hydrochloric acid in gastric juice, but these drugs can only reduction of patient it is ailing, it is difficult to effect a radical cure sufferer, and have Certain toxic side effect.
Invention content
In view of this, the purpose of the present invention is to provide a kind of Chinese medicine composition for treating gastritis, which treats It imitates definite, quick and has no toxic side effect.
In order to achieve the above objectives, the present invention provides the following technical solutions:
1. a kind of Chinese medicine composition for treating gastritis, which is characterized in that by daily medication gauge, by following weight proportioning Bulk pharmaceutical chemicals are made:16-30 grams of Cortex Magnoliae Officinalis, 16-30 grams of Fructus Aurantii, 16-30 grams of green peel, 16-30 grams of dried orange peel, 16-30 grams of root of Aucklandia lappa Decne, the shell of areca nut 16-30 grams, 16-30 grams of umbellate pore furgus, 16-30 grams of rhizoma alismatis, 16-30 grams of Poria cocos, 6-9 grams of akebi, 12-25 grams of ginger peel, Radix Codonopsis 12-25 Gram, 16-30 grams of motherwort, 16-30 grams of Radix Angelicae Sinensis, 12-25 grams of safflower, 12-25 grams of Stephania tetrandra, 12-25 grams of cassia twig and stone reed 16-30 Gram.
Further, daily medication gauge is pressed, the bulk pharmaceutical chemicals matched by following weight are made:18-28 grams of Cortex Magnoliae Officinalis, Fructus Aurantii 18- 28 grams, 18-28 grams of green peel, 18-28 grams of dried orange peel, 18-28 grams of root of Aucklandia lappa Decne, 18-28 grams of the shell of areca nut, 18-28 grams of umbellate pore furgus, rhizoma alismatis 18-28 Gram, it is 18-28 grams of Poria cocos, 6-9 grams of akebi, 15-22 grams of ginger peel, 15-22 grams of Radix Codonopsis, 18-28 grams of motherwort, 18-28 grams of Radix Angelicae Sinensis, red 18-28 grams of 15-22 grams of flower, Stephania tetrandra 15-22,15-22 grams of cassia twig and stone reed.
Further, daily medication gauge is pressed, the bulk pharmaceutical chemicals matched by following weight are made:23 grams of Cortex Magnoliae Officinalis, 23 grams of Fructus Aurantii, blueness 23 grams of skin, 23 grams of dried orange peel, 23 grams of root of Aucklandia lappa Decne, 23 grams of the shell of areca nut, 23 grams of umbellate pore furgus, 23 grams of rhizoma alismatis, 23 grams of Poria cocos, 8 grams of akebi, ginger peel 18 Gram, 18 grams of Radix Codonopsis, 23 grams of motherwort, 23 grams of Radix Angelicae Sinensis, 18 grams of safflower, 18 grams of Stephania tetrandra, 23 grams of 18 grams of cassia twig and stone reed.
2. application of the Chinese medicine composition described above in the drug for preparing treatment gastritis.
Further, the gastritis is chronic gastritis.
Further, by conventional drug formulation process by the Chinese medicine composition be prepared into aqua, granule, capsule or Tablet.
The pharmacological action of each Chinese medicine:
Cortex Magnoliae Officinalis:It is bitter, acrid in flavour and warm in nature.Returns spleen, stomach, lung, large intestine channel.Effect with cure mainly:Eliminating dampness dissolving phlegm, lower gas removes full.For humidity hysteresis In wound, abdominal swelling and diarrhea, stagnation of QI due to dyspepsia, abdominal distention constipation, sputum cough.
Fructus Aurantii:It is bitter, pungent, sour, it is slightly cold.Returns spleen, stomach.Effect with cure mainly:Regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row.For chest side of body gas Stagnant, turgor pain, accumulation of food in the stomach and intes tine due to indigestion stops in phlegm and retained fluid, visceral organ ptosis.
Green peel:It is bitter, acrid in flavour and warm in nature.Return liver, courage, stomach.Effect with cure mainly:Soothing the liver relieving stagnant Qi, disperse accumulationization are stagnant.For distending pain in the chest and hypochondrium, Hernia pain, newborn addiction, acute mastitis, stagnation of QI due to dyspepsia, abdominal distention
Dried orange peel:It is bitter, acrid in flavour and warm in nature.Return lung, the spleen channel.Effect with cure mainly:Regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm.For abdominal fullness and distention, food It is few to vomit and diarrhoea, coughing with a lot of sputum.
Root of Aucklandia lappa Decne:It is pungent, bitter, temperature.Returns spleen, stomach, large intestine, three burnt, gallbladder channels.Effect with cure mainly:Promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.With In chest side of body, abdominal distention, weight after rush down dysentery, dyspepsia, do not feel like eating.Roasted RADIX AUCKLANDIAE reality intestines antidiarrheal.For stomachache of having loose bowels.
The shell of areca nut:It is pungent, tepor.Returns spleen, stomach, large intestine, small intestinl channel.Effect with cure mainly:During promoting the circulation of qi is wide, line water detumescence.For Retention of damp leading to blockage of QI, it is bored that gastral cavity abdomen is swollen, not well, oedema turgor of defecating, beriberi edema, difficult urination.
Umbellate pore furgus:It is sweet, light, it puts down.Return kidney, bladder warp.Effect with cure mainly:Clearing damp and promoting diuresis.For difficult urination, oedema, diarrhea, Stranguria with turbid discharge, under.
Rhizoma alismatis:It is sweet, light, it trembles with fear.Return kidney, bladder warp.Effect with cure mainly:Clearing damp and promoting diuresis expels the heat-evil, and changes turbid lipid-loweringing.For urine It is unfavorable, oedema turgor, oliguria of having loose bowels, phlegmatic vertigo, puckery pain of heat gonorrhea, hyperlipidemia.
Poria cocos:It is sweet, light, it puts down, the thoughts of returning home, lung, spleen, kidney channel.Effect with cure mainly:Clearing damp and promoting diuresis, invigorating the spleen calming heart.It is urinated for oedema It is few, phlegm retention anti-dazzle nervous, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Akebi:Hardship is trembled with fear.The thoughts of returning home, small intestine, bladder warp.Effect with cure mainly:Inducing diuresis for treating strangurtia, relieving restlessness that clears away heart-fire are newborn under promoting menstruation.With In stranguria, oedema, red, the aphthae of vexed urine, Amenorrhea breast is few, damp and hot numbness pain.
Ginger peel:It is pungent, it is cool, it trembles with fear and nontoxic.Lung, line water detumescence drop with spleen.
Radix Codonopsis:Sweet and neutral.Returns spleen, lung channel.Effect with cure mainly:Strengthening spleen and tonifying lung, nourishes blood and promotes the production of body fluid.For spleen-lung Qi deficiency, deficiency of food is tired It is idle, false asthma cough, insufficiency of vital energy and blood, sallow complexion, palpitation, injury thirst, Heat Diabetes.
Motherwort:It is bitter, pungent, it is slightly cold.Return liver, pericardium, bladder warp.Effect with cure mainly:Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema, heat-clearing Removing toxic substances.For irregular menstruation, dysmenorrhoea Amenorrhea, lochiorrhagia, oedema oliguria, sore swollen toxin
Radix Angelicae Sinensis:Sweet, acrid, warm.Return liver, the heart, the spleen channel.Effect with cure mainly:Replenishing and activating blood, menstruction regulating and pain relieving relax bowel.For Blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, closed dysmenorrhea, asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sores, intestinal dryness Constipation.Prepared RADIX ANGELICAE SINENSIS with yellow rice wine invigorate blood circulation.For closed dysmenorrhea, arthralgia pain due to rheumatism, injury from falling down.
Safflower:It is acrid in flavour and warm in nature.Converge to heart and liver channels.Effect with cure mainly:Invigorate blood circulation, removing blood stasis and analgesics.For Amenorrhea, dysmenorrhoea, lochia Not all right , abdominal mass and lump, chest impediment and cardialgia, stasis of blood, chest side of body twinge, injury from falling down, sore swell and ache curative.
Stephania tetrandra:Hardship is trembled with fear.Return bladder, lung channel.Effect with cure mainly:Wind-expelling pain-stopping, inducing diuresis for removing edema are used for arthralgia pain due to rheumatism, water Swollen tinea pedis, difficult urination, eczema sore.
Cassia twig:Acrid, sweet, warm.The thoughts of returning home, lung, bladder warp.Effect with cure mainly:Sweating expelling pathogenic factors from muscles and skin, warming meridian, helps yang transforming qi are put down Spin gas.For anemofrigid cold, coldness and pain in the epigastrium, blood trembles with fear Amenorrhea, joint pain, phlegm and retained fluid, oedema, palpitaition, run quickly globefish.
Stone reed:Smell is bitter, flat, poison.Hair is used on defoliation.Effect with cure mainly:Labor heat evil gas is used for diuresis water channel, leads to five Leaching is only tired of lower gas, leads to bladder, controls leaching, root disappear the horizontal gas of chest diaphragm make it is swollen.
Modern medical theory is thought:Chronic gastroenteritis means various chronic stomach lining inflammatory lesions caused by different pathogeny, Its main clinical manifestation is anorexia, epigastric discomfort and secret anguish, belch, pantothenic acid, Nausea and vomiting etc..Chinese medicine thinks that stomach is Positive soil, more more blood of gas cause patient, it is middle it is burnt it is stagnant can hold back, be unable to that receiving is decomposed to be made so, chronic gastritis is more with real example.It is clinical It is draw eating and drinking without temperance more, addiction raw food, impairing the spleen and stomach, so that spleen not transporting, stomach Qi rising, depression and stagnation of QI."Interior warp"" the institute of heresy Gather, gas must be empty " the different weakness of the spleen and the stomach performance of Patients with Chronic Gastritis generally existing weight, and chronic gastritis " prolonged illness must the stasis of blood ", Blood stasis leads to gastric mucosa hypoxic-ischemic.Treat chronic gastritis, it is necessary to which warming middle-JIAO and strengthening the spleen, dispersing stagnated hepatoqi and stomach can be only achieved treatment effect Fruit.Medicament composing prescription of the present invention, actual situation are taken into account, lift and mutually assist, and can not only expel the heat-evil clear stagnant, anorexia, abdominal pain, evil is effectively relieved The clinical symptoms such as the heart, vomiting, and quickly diminish inflammation, effectively treat chronic gastritis;Can also be with stomach and alleviating pain soothing the liver, reaching prevents again The purpose of hair;To achieve the purpose that treating both manifestation and root cause of disease.
The beneficial effects of the present invention are:Radix Codonopsis, dried orange peel regulating qi-flowing for harmonizing stomach, strengthening spleen and tonifying lung in drug of the present invention.Improve body Immunity function, enhancing barrier of gastric mucosa effect, prevents the invasion of disease and evil.Cortex Magnoliae Officinalis, Fructus Aurantii, the shell of areca nut, umbellate pore furgus, rhizoma alismatis, akebi and Root of Aucklandia lappa Decne expels the heat-evil clear stagnant, adjusts the gastrointestinal movement rhythm and pace of moving things, improves gastroenteritic power and promote gastrointestinal peristalsis, promote the emptying of stomach.Green peel, Cassia twig relieves pain soothing the liver relieving stagnant Qi, Yangyin Rougan liver, mitigates the effect of abdominal distention or analgesic, the negative feelings such as further antidepression and anxiety Thread and other effects.Motherwort is clearing heat and detoxicating, effective to helicobacter pylori, promotes human metabolism, is conducive to inflammation recovery.With red Spend it is promoting blood circulation and removing blood stasis, Chinese angelica blood supplementing promoting blood circulation, fully improve gastric mucosa blood circulation, increase gastric mucosa blood supply, recession inflammatory lesions, Promote gastric mucosal cell regeneration and injury tissue reparation.Lung drops in ginger peel and spleen, and line water detumescence, can disappear diaphragm choke turgor, with dried orange peel master The effect of playing promoting digestion to act on, all medicines share, invigorating the spleen, analgesic, dispersing stagnated hepatoqi can be played well.The present invention is with day Right Chinese medicine is raw material, treats chronic gastritis using the comprehensive function of each taste medicine, warming middle-JIAO and strengthening the spleen, dispersing stagnated hepatoqi and stomach and alleviating pain are flat Liver reaches therapeutic effect together.Its drug effect has synergistic effect, has no toxic and side effect to human body, and cheap, curative for effect, Treating both manifestation and root cause of disease is achieved the purpose that.Chronic gastritis and uneasy to recur can be effectively cured, totall effective rate in clinical treatment 92% is worth pushing away It is wide to use.
Specific implementation mode
The preferred embodiment of the present invention is described in detail below.The experiment side of actual conditions is not specified in embodiment Method, usually according to conventional conditions or according to the manufacturer's recommendations.
Embodiment 1
The Chinese medicine composition for treating chronic gastritis, by daily medication gauge, the bulk pharmaceutical chemicals matched by following weight are made:
Cortex Magnoliae Officinalis 23g, Fructus Aurantii 23g, green peel 23g, dried orange peel 23g, root of Aucklandia lappa Decne 23g, shell of areca nut 23g, umbellate pore furgus 23g, rhizoma alismatis 23g, Fu Siberian cocklebur 23g, akebi 8g, ginger peel 18g, Radix Codonopsis 18g, motherwort 23g, Radix Angelicae Sinensis 23g, safflower 18g, Stephania tetrandra 18g, cassia twig 18g and stone Reed 23g.
Decoction prepares and instructions of taking:It is decocted in water for oral dose, one dose per day divides sooner or later one after each meal twice.
In addition to being decocted in water for oral dose, can also by conventional drug formulation process by the Chinese medicine composition be prepared into granule, Capsule or tablet.
Embodiment 2
The Chinese medicine composition for treating chronic gastritis, by daily medication gauge, the bulk pharmaceutical chemicals matched by following weight are made:
18 grams of Cortex Magnoliae Officinalis, 18 grams of Fructus Aurantii, 18 grams of green peel, 18 grams of dried orange peel, 18 grams of root of Aucklandia lappa Decne, 18 grams of the shell of areca nut, 18 grams of umbellate pore furgus, rhizoma alismatis 18 grams, 18 grams of Poria cocos, 8 grams of akebi, 15 grams of ginger peel, 15 grams of Radix Codonopsis, 18 grams of motherwort, 18 grams of Radix Angelicae Sinensis, 15 grams of safflower, Stephania tetrandra 15 Gram, 18 grams of 15 grams of cassia twig and stone reed.
Embodiment 3
The Chinese medicine composition for treating chronic gastritis, by daily medication gauge, the bulk pharmaceutical chemicals matched by following weight are made:
20 grams of Cortex Magnoliae Officinalis, 20 grams of Fructus Aurantii, 20 grams of green peel, 22 grams of dried orange peel, 22 grams of root of Aucklandia lappa Decne, 22 grams of the shell of areca nut, 22 grams of umbellate pore furgus, rhizoma alismatis 20 grams, 20 grams of Poria cocos, 8 grams of akebi, 16 grams of ginger peel, 16 grams of Radix Codonopsis, 25 grams of motherwort, 25 grams of Radix Angelicae Sinensis, 18 grams of safflower, Stephania tetrandra 18 Gram, 22 grams of 18 grams of cassia twig and stone reed.
Embodiment 4
The Chinese medicine composition for treating chronic gastritis, by daily medication gauge, the bulk pharmaceutical chemicals matched by following weight are made:
28 grams of Cortex Magnoliae Officinalis, 28 grams of Fructus Aurantii, 28 grams of green peel, 28 grams of dried orange peel, 28 grams of root of Aucklandia lappa Decne, 28 grams of the shell of areca nut, umbellate pore furgus 28, rhizoma alismatis 28 Gram, 28 grams of Poria cocos, 8 grams of akebi, 22 grams of ginger peel, 22 grams of Radix Codonopsis, 28 grams of motherwort, 28 grams of Radix Angelicae Sinensis, 22 grams of safflower, Stephania tetrandra 22 Gram, 28 grams of 22 grams of cassia twig and stone reed.
The preparation method is the same as that of Example 1.
One, clinical data
1, clinical data:Choose the Patients with Chronic Gastritis 100 in May, 2016 in March, 2018, man 55, female 45. It is the oldest 72 years old, 25 years old minimum, it is average:45 years old.Course of disease longest 11 years, it is most three months short.All have apparent abdominal distension abdominal pain, The clinical symptoms such as belch, sour regurgitation, gastrorrhagia, anorexia, burning sensation.
2, diagnostic criteria:
For chronic gastritis symptom without specificity, sign is seldom, and x-ray inspection, which generally aids in, excludes other stomach trouble diseases.It makes a definite diagnosis Using gastrocopy and gastric mucosa biopsy.
3, therapy:Wherein Chinese medicine of the present invention is taken by treatment group, is decocted in water for oral dose, one dose per day, divides sooner or later aftermeals twice With 21 days are 1 course for the treatment of.
4, curative effect determinate standard:
It cures:Clinical symptoms disappear after treatment, and gastroscope checks no active inflammation, and chronic inflammation improves.Organize biopsy Pathologic finding is consistent with gastrocopy conclusion, Non-gland body atrophy and dysplasia;
It is effective:Clinical symptoms disappear, and gastroscope checks gastric mucosa no inflammation, and chronic inflammation improves, and organizes biopsy pathology inspection Body of gland atrophy and dysplasia, intestinesization significantly mitigate;
Effectively:Main clinic symptoms mitigate, and gastroscope checks extent of disease and reduces 50% or more, and inflammation is alleviated, and organizes biopsy Show that inflammation mitigates, body of gland atrophy and dysplasia, intestinesization significantly mitigate;
In vain:Not up to above-mentioned standard.
Overall clinical efficacy rate=cure rate+obvious effective rate+effective percentage.
5, treatment results:In Clinical practice drug of the present invention, 100 patients of medication, after 1 course for the treatment of of taking medicine, symptom is bright It is aobvious to alleviate, after continuing 2 courses for the treatment of of medication, fully recover 12, effective 25, effective 55, total effective rate 92%.
Two, model case
Case 1:Week certain, man, 47 years old, civil servant, on April 15th, 2017 was medical:Heart-burn repeatedly for many years, after drinking particularly Seriously.Take a variety of Western medicine, when it is light when weight.Gastrocopy is diagnosed as superficial gastritis.Using drug of the present invention.Take embodiment 1 Decoction further consultation after 21 days prepared by Chinese medicine composition, clinical symptoms disappear.Gastroscope checks mucous membrane chronic inflammation and disappears.It is electric after 1 year Follow-up is talked about without recurrence.
Case 2:It is bent certain, female, 38 years old.Shop-assistant.On December 4th, 2017 is medical.Epigastric distending pain, belch frequently, sour regurgitation.Really Examine chronic gastritis 2 years.After medication repeatedly.Using drug of the present invention.The decoction of 1 Chinese medicine composition of embodiment preparation is taken after 10 days Further consultation, symptom are substantially reduced.Further consultation behind days on the 21st, all symptoms disappear.Effect of follow-up visit by telephone is without recurrence after 1 year.
The invention prescription is conducive to improve curative effect, reduces complication and adverse reaction, and patient body is promoted to get well.Energy The clinical therapeutic efficacy of patient is enough significantly improved, and reduces the incidence of adverse reaction, it is safe, and adverse reaction is small.
Finally illustrate, preferred embodiment above is merely illustrative of the technical solution of the present invention and unrestricted, although logical It crosses above preferred embodiment the present invention is described in detail, however, those skilled in the art should understand that, can be Various changes are made to it in form and in details, without departing from claims of the present invention limited range.

Claims (6)

1. a kind of Chinese medicine composition for treating gastritis, which is characterized in that by daily medication gauge, the raw material matched by following weight Medicine is made:16-30 grams of Cortex Magnoliae Officinalis, 16-30 grams of Fructus Aurantii, 16-30 grams of green peel, 16-30 grams of dried orange peel, 16-30 grams of root of Aucklandia lappa Decne, shell of areca nut 16- 30 grams, 16-30 grams of umbellate pore furgus, 16-30 grams of rhizoma alismatis, 16-30 grams of Poria cocos, 6-9 grams of akebi, 12-25 grams of ginger peel, 12-25 grams of Radix Codonopsis, benefit 16-30 grams of 16-30 grams of Brittle Falsepimpernel Herb, 16-30 grams of Radix Angelicae Sinensis, 12-25 grams of safflower, 12-25 grams of Stephania tetrandra, 12-25 grams of cassia twig and stone reed.
2. the Chinese medicine composition for the treatment of gastritis according to claim 1, which is characterized in that by daily medication gauge, under The bulk pharmaceutical chemicals for stating weight proportion are made:18-28 grams of Cortex Magnoliae Officinalis, 18-28 grams of Fructus Aurantii, 18-28 grams of green peel, 18-28 grams of dried orange peel, root of Aucklandia lappa Decne 18-28 grams, 18-28 grams of the shell of areca nut, 18-28 grams of umbellate pore furgus, 18-28 grams of rhizoma alismatis, 18-28 grams of Poria cocos, 6-9 grams of akebi, ginger peel 15-22 Gram, 15-22 grams of Radix Codonopsis, 18-28 grams of motherwort, 18-28 grams of Radix Angelicae Sinensis, 15-22 grams of safflower, Stephania tetrandra 15-22,15-22 grams of cassia twig With 18-28 grams of stone reed.
3. the Chinese medicine composition for the treatment of gastritis according to claim 1, which is characterized in that by daily medication gauge, under The bulk pharmaceutical chemicals for stating weight proportion are made:23 grams of Cortex Magnoliae Officinalis, 23 grams of Fructus Aurantii, 23 grams of green peel, 23 grams of dried orange peel, 23 grams of root of Aucklandia lappa Decne, the shell of areca nut 23 Gram, 23 grams of umbellate pore furgus, 23 grams of rhizoma alismatis, 23 grams of Poria cocos, 8 grams of akebi, 18 grams of ginger peel, 18 grams of Radix Codonopsis, 23 grams of motherwort, 23 grams of Radix Angelicae Sinensis, 23 grams of 18 grams of safflower, 18 grams of Stephania tetrandra, 18 grams of cassia twig and stone reed.
4. according to application of any one of the claim 1-3 Chinese medicine compositions in the drug for preparing treatment gastritis.
5. application according to claim 4, which is characterized in that the gastritis is chronic gastritis.
6. application according to claim 4, which is characterized in that by conventional drug formulation process by the Chinese traditional medicine composition Object is prepared into aqua, granule, capsule or tablet.
CN201810991894.3A 2018-08-29 2018-08-29 A kind of Chinese medicine composition that treating gastritis and its application Pending CN108686197A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170124249A (en) * 2016-05-02 2017-11-10 란핑 리우 tonic tea
CN107929692A (en) * 2017-12-11 2018-04-20 佛山市腾瑞医药科技有限公司 A kind of gastritis, Changyan Keli and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170124249A (en) * 2016-05-02 2017-11-10 란핑 리우 tonic tea
CN107929692A (en) * 2017-12-11 2018-04-20 佛山市腾瑞医药科技有限公司 A kind of gastritis, Changyan Keli and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
郁东海等: "《治未病学》", 31 May 2018 *

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Application publication date: 20181023