CN113230344A

CN113230344A - Traditional Chinese medicine composition for preventing and treating alopecia and preparation method thereof

Info

Publication number: CN113230344A
Application number: CN202110688011.3A
Authority: CN
Inventors: 刘佳
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-06-21
Filing date: 2021-06-21
Publication date: 2021-08-10

Abstract

The invention belongs to the technical field of Chinese herbal medicines, and discloses a traditional Chinese medicine composition for preventing and treating alopecia and a preparation method thereof. Fructus toosendan is used as a monarch drug, has bitter and cold property, enters liver, small intestine and bladder channels, soothes liver, promotes qi circulation and relieves pain; the ligusticum wallichii, the aloe and the asarum are used as ministerial drugs, and the ligusticum wallichii is pungent, warm, slightly sweet and enters liver and gallbladder channels to promote qi circulation and relieve depression; aloe is bitter and cold in nature, and has effects of tonifying heart and promoting blood circulation; asarum, pungent in flavor and warm in nature, enters heart, lung and kidney meridians, warms lung and promotes diuresis; the monarch and minister medicines are compatible, and the mint, the divaricate saposhnikovia root and the borneol are added for assisting, relieving exterior syndrome and sweating, and together playing the efficacies of tonifying kidney and nourishing blood, dispelling wind and clearing heat, promoting qi circulation and resolving depression and activating blood. The components have the health care and rehabilitation effects on skin and hair metabolism due to the matching of the sex, flavor, meridian tropism and symptoms of alopecia and exterior deficiency. The preparation process is simple, only the raw materials are ground into powder, the loss is reduced, the energy is saved, the consumption is reduced, and the safety is realized. The medicine powder is adhered to the surface of nasal mucosa by a drug administration method of nasal livestock inhalation, and the effective components of the medicine powder are quickly absorbed by rich capillaries on the surface of the mucosa to exert curative effect.

Description

Traditional Chinese medicine composition for preventing and treating alopecia and preparation method thereof

Technical Field

The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a traditional Chinese medicine composition for preventing and treating alopecia and a preparation method thereof.

Background

At present, most of the existing traditional Chinese medicine preparations for preventing and treating alopecia in the market directly or indirectly act on hair by taking traditional methods such as oral administration, soaking, smearing and the like as administration routes, however, all the known traditional Chinese medicines and health care products for treating alopecia have some defects of the traditional Chinese medicines and the health care products, particularly the defects of inaccurate curative effect, troublesome use, large side effect, high recurrence rate and the like, and part of patients are always worried about preventing and treating alopecia or lose confidence.

The theory of traditional Chinese medicine considers that the alopecia is closely related to the kidney, the liver and the spleen, the liver, the kidney and the spleen are used as the main factors, the rheumatism heat pulsation is used as the target, the syndromes are mixed with deficiency and excess, and the pathogenesis is complicated; the western medicine considers that the alopecia is the result of multifactorial combined action and relates to infection, hormone level, immunoregulation, cell factors, growth factors, stress, heredity and the like, and the pathogenesis of the alopecia is directly related to the dysfunction of the endocrine-immune-nervous system of a human body. From the perspective of modern medicine, alopecia, regardless of complex causes, is caused by a decrease or interruption of the local blood supply around the hair follicle. Besides genetic or traumatic scars, many other factors such as infection, gland blockage, neuropsychiatric factors, hyperpyrexia, endocrine abnormalities, etc. Therefore, the main symptoms of alopecia belong to exterior deficiency in the theory of traditional Chinese medicine. Herbs with actions of breaking qi, ascending qi and pungent-heat are contraindicated for exterior deficiency syndrome.

With the development of the health industry of traditional Chinese medicine, mucosal administration becomes a supplement of the traditional administration method due to a novel administration way and good patient adaptability, and has good application prospect. However, at present, extensive and intensive research into dosage forms, methods, techniques and the like of Chinese and western medicines administered by nasal mucosa in clinical medicine at home and abroad has been carried out, and certain progress has been made, such as nasal spray, nasal drip irrigation, nasal cavity patch and the like. Not only is complicated, but also can not ensure whether the effective components can be separated out efficiently in the preparation process, and the like, and has problems.

Disclosure of Invention

In order to solve the problems in the prior art, the invention aims to provide a traditional Chinese medicine composition for preventing and treating alopecia and a preparation method thereof.

The technical scheme adopted by the invention is as follows: a traditional Chinese medicine composition for preventing and treating alopecia is mainly prepared from the following raw materials in parts by mass:

3-20 parts of ligusticum wallichii, 12-40 parts of szechwan chinaberry fruit, 3-15 parts of asarum, 15-45 parts of aloe, 3-15 parts of mint, 1-5 parts of divaricate saposhnikovia root and 0.1-0.5 part of borneol.

The invention provides a Chinese medicinal composition for preventing and treating alopecia, which takes Szechwan Chinaberry fruit as a monarch drug, has bitter and cold property, enters liver, small intestine and bladder channels, and is used for soothing liver, promoting qi circulation and relieving pain; the ligusticum wallichii, the aloe and the asarum are used as ministerial drugs, and the ligusticum wallichii is pungent, warm, slightly sweet and enters liver and gallbladder channels to be used for promoting qi circulation and dispelling melancholy, dispelling wind-dryness and dampness, and activating blood and relieving pain; aloe is bitter and cold in nature, and can be used for killing bacteria, relieving inflammation, moistening skin, invigorating stomach, promoting excretion, tonifying heart, promoting blood circulation, enhancing immunity, promoting regeneration, and removing toxic substance; the asarum is pungent and spicy in flavor and numb tongue, warm in nature, enters heart, lung and kidney channels, and has the effects of expelling wind, dispelling cold, warming lung, promoting diuresis and inducing resuscitation; the monarch and ministerial medicines are compatible, and the mint, the divaricate saposhnikovia root and the borneol are added for assisting, so that the effects of relieving exterior syndrome and sweating, dispelling wind and removing dampness, and dispersing stagnated fire are achieved, and the effects of tonifying kidney and nourishing blood, dispelling wind and clearing heat, promoting qi circulation and resolving depression and invigorating blood circulation are achieved. The composition belongs to the medicine for astringing, tonifying qi, strengthening the exterior and being sweet and sour, and all components are matched with the exterior deficiency symptom of alopecia. The composition has good improving effect on alopecia areata, seborrheic alopecia, and symptomatic alopecia caused by neuropsychiatric factors, and accompanied scalp pruritus, dizziness, tinnitus, soreness of waist and knees, etc. In addition, the health-care wine has certain health-care and rehabilitation effects on normal physiological metabolism of skin and hair due to the action mechanisms of tonifying kidney, nourishing blood, dispelling wind, clearing heat, promoting qi circulation, relieving depression and activating blood circulation.

Preferably, the composition is mainly prepared from the following raw materials in parts by mass:

5-15 parts of ligusticum wallichii, 20-30 parts of szechwan chinaberry fruit, 5-10 parts of asarum, 20-30 parts of aloe, 4-10 parts of mint, 2-4 parts of divaricate saposhnikovia root and 0.2-0.3 part of borneol.

10 parts of ligusticum wallichii, 35 parts of szechwan chinaberry fruit, 8 parts of asarum, 25 parts of aloe, 8 parts of mint, 3 parts of divaricate saposhnikovia root and 0.25 part of borneol.

Ligusticum wallichii (with the scientific name of Ligusticum chuanxiong ghort) is cultivated in Sichuan (Shuichuan county) and grows in the places of Yunnan, Guizhou, Guangxi and the like in mild climatic environment. Is a traditional Chinese medicine plant which is commonly used for promoting blood circulation and promoting qi circulation, dispelling wind and relieving pain, and the ligusticum wallichii is pungent, warm, fragrant and dry and can disperse and ascend to the vertex; it enters the blood system and goes down to reach the blood sea. Promoting blood circulation and removing blood stasis, and is suitable for various diseases caused by blood stasis; can be used for treating headache due to wind, and rheumatalgia. Xiren is that Chuan Xiong is a qi-flowing medicine in blood, but it has the functions of dispersing acrid, relieving depression, dredging and relieving pain. Pungent, slightly sweet and warm in nature. Entering liver and gallbladder meridians. Move qi and relieve depression, dispel wind-dryness and dampness, activate blood and alleviate pain. It is indicated for wind-cold headache, dizziness, hypochondriac pain, abdominal pain, cold arthralgia, spasm of tendons, amenorrhea, dystocia, postpartum pain due to blood stasis, carbuncle, cellulitis, sore and ulcer. Can be used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal pain, pricking pain in chest and hypochondrium, traumatic injury, swelling and pain, headache, and rheumatalgia.

Chuan Lian Zi, name of Chinese traditional medicine. Is dried mature fruit of Melia toosendan (Meliosendan Sieb. et Zucc.) belonging to Meliaceae. The chemical components comprise toosendanin, alkaloid, kaempferol, resin, and tannin. Nature, flavor and meridian tropism; bitter and cold; has little toxicity. It enters liver, small intestine and bladder meridians. The functional indications are as follows: soothing liver, moving qi, alleviating pain, expelling parasites. Can be used for treating chest and hypochondrium, abdominal distention and pain, hernia pain, and abdominal pain due to parasitic infestation.

Asarum, also known as asarum: asarum sieboldii, latin name: asarum sieboldii miq is a perennial herb of the genus asarum, family aristolochiaceae, class dicotyledonae. Has the effects of expelling wind, dispelling cold, promoting diuresis and inducing resuscitation. And has the functions of treating wind cold headache, nasosinusitis, toothache, phlegm and fluid retention cough, rheumatism, etc. The functional indications are as follows: relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging orifices, warming lung, and eliminating phlegm. Can be used for treating common cold due to wind-cold, headache, toothache, nasal obstruction, nasal discharge, allergic rhinitis, nasosinusitis, rheumatic arthralgia, phlegm and fluid retention, and cough and asthma. As a medicinal plant, Asarum sieboldii is listed as the superior product in Shen nong's herbal Jing (Shen nong's herbal Jing). Liaojingxi has thin root, grey yellow color, green leaf color, pungent and spicy taste and numb tongue. Warm in nature and with little toxicity. It enters heart, lung and kidney meridians. Has effects in expelling pathogenic wind, expelling cold, warming lung, promoting diuresis, and inducing resuscitation. It is used to treat headache due to wind-cold evil, nasosinusitis, toothache, phlegm and fluid retention, cough, and rheumatalgia. In addition, herba asari also has antiinflammatory, immunity enhancing, local anesthesia, metabolism improving, and antibacterial effects, and can be used for treating leukopenia caused by chemotherapy and radiotherapy for tumor patients. Nature, flavor and meridian tropism: pungent and warm. It enters heart, lung and kidney meridians. The herba asari whole plant contains volatile oil 2.5%, the main components of the oil are methyl eugenol, safrole ether, asarone, elemene, and also contains eugenone, efamol, pinene, camphene, eucalyptol, dl-demethyl equilibrium linderamine (dl-demethylthioclaurine, hignamine), pungent substance of piperitamine and (2E, 4E, 8Z, 10E) -N-isobutyl-2, 4, 8, 10-dodecatetraenoic amide, etc. the herba asari whole plant contains volatile oil 2.6%, the main components of the oil are alpha-thujene (alpha-thujene), myrcene (myrcene), gamma-terpineol and elemene, the asarum sieboldii also contains N-pentadecane, sitosterol, campesterol, stigmasterol, sesamin, N-isobutyl tetradecatetraenamide and the like. The herba asari contains volatile oil 1%, eugenone as main ingredient, and alpha-or beta-pinene, eucalyptol (1, 8-cinede), methyl eugenol, safrole, alpha-methoxy safrole, elemene, asarone, etc.

Aloe, (academic name: Aloe vera) Aloe, is a perennial evergreen herb of the Liliaceae family, with efficacy: purging fire; detoxification; removing blood stasis; killing pests. Blood-shot eyes; constipation; white turbidity; hematuria; infantile convulsions; malnutrition; burns and scalds; amenorrhea in women; hemorrhoids; scabies; carbuncle and furuncle; traumatic injury. The pharmacological action is as follows: antibacterial, antiinflammatory, moistening, skin caring, stomach invigorating, diarrhea relieving, heart tonifying, blood circulation promoting, immunity and regeneration promoting, immunity and anti-tumor, toxic materials clearing away, antiaging, analgesic, tranquilizing, and sunscreen effects. Nature and taste: bitter and cold.

Mint, the Latin scientific name (MenthahalocalyxBriq.), is called "Yindancao" which is a plant of the Labiatae family, i.e., other dry whole herbs of the same genus. Mint is one of the common Chinese traditional medicines. It is a pungent and cool sweating antipyretic, and can be used for treating influenza, headache, conjunctival congestion, fever, and swelling and pain of throat and gum. It can be used for treating neuralgia, skin pruritus, erythra, eczema, etc. Herba Menthae is usually used instead of tea for clearing away heart-fire and improving eyesight. Herba Menthae is a common Chinese medicine, and young tender stem tip can be eaten as vegetable, and whole herb can be used as medicine, and can be used for treating common cold, fever, laryngalgia, headache, conjunctival congestion, myalgia, skin rubella pruritus, measles without adequate eruption, and also has effects on carbuncle, cellulitis, scabies, tinea, and dermatitis. The mint contains menthol, and the substance can refresh breath, has various medicinal properties, can relieve abdominal pain and gallbladder problems such as spasm, and also has antiseptic, antibacterial, diuretic, expectorant, stomach invigorating and digestion promoting effects. Eating a large amount of mint can cause insomnia, but eating a small amount of mint can help sleep.

Ledebouriella root (saposhnikovia divaricata (Trucz.) Schischk.) perennial herb is used as root medicine, and is one of the famous medicinal materials in northeast China. Has effects of inducing perspiration, eliminating phlegm, dispelling pathogenic wind, relieving exterior syndrome, and relieving pain, and can be used for treating common cold, headache, arthralgia, and neuralgia. Fang Feng is used as root medicine. Pungent and sweet in flavor and warm in nature. Has effects in relieving exterior syndrome, inducing perspiration, dispelling pathogenic wind, and removing dampness, and can be used for treating wind-cold type common cold, headache, fever, joint pain, and tetanus; in addition, Ledebouriella root flower, also can be used for medicine.

Borneol, other names: borneolum, Borneolum Syntheticum, borneolum, Borneolum Syntheticum, and Borneolum Syntheticum. The main components are as follows: the product is crystal obtained from resin and volatile oil of Borneolum, and is almost pure dextroborneol. The resin and volatile oil of Borneolum contain various terpenoids. In addition to borneol, it also contains parthenone such as humulene, beta-elemene, caryophyllene, etc., and triterpenoid such as oleanolic acid, hordenic acid, asiatic acid, camphol ketone, coca glycol, etc. Pungent and bitter taste, slightly cold. Enter heart and lung meridians. Unblocking orifices, dispelling stagnated fire, removing nebula, improving eyesight, relieving swelling and alleviating pain. It is indicated for wind stroke, vomiting, coma due to febrile disease, epilepsy due to convulsion, phlegm-phlegm, qi block, deafness, sore throat, aphtha, otitis media, carbuncle, swelling, hemorrhoid, nebula, and enterobiasis.

A preparation method of a traditional Chinese medicine composition for preventing and treating alopecia comprises the steps of selecting ligusticum wallichii, szechwan chinaberry fruit, asarum, aloe, mint, divaricate saposhnikovia root and borneol according to corresponding proportions, respectively drying, mixing, grinding and sieving to obtain a finished product.

The preparation method of the traditional Chinese medicine composition for preventing and treating alopecia is simple in preparation process, only the raw materials are ground into powder, so that the content of effective ingredients in the raw materials is ensured to the maximum extent, the loss is reduced, the energy is saved, the consumption is reduced, the safety is realized, and the traditional Chinese medicine composition is suitable for mass production in factories.

Preferably, the drying temperature is 10-35 ℃.

Preferably, the filter screen is a 100-200-mesh filter screen.

Preferably, the finished product is in powder form.

A traditional Chinese medicine composition for preventing and treating alopecia is administered by adopting a nasal livestock inhalation method.

Preferably, the composition is applied by sticking the traditional Chinese medicine composition for preventing and treating alopecia by fingers, is put into nostrils, and is applied by powder to reach the position of mucous membrane.

Preferably, the amount to be administered is 0.1 to 0.3 g/time.

In the above administration method, the Chinese medicinal composition is adhered to fingers, and is placed into nostrils, and then the powder is gently inhaled until the powder reaches the mucosa position, thereby completing the whole administration process. The light inhalation mode in the actual operation process is a method for avoiding drug invalidation caused by inhalation of medicinal powder into respiratory tract of a user, and belongs to a mode which can be realized conventionally, and the mode only belongs to an operation method for medication and does not reflect the result of treatment means for living animals and the like.

The drug delivery method of the nasal mucosa is characterized in that the drug powder is adhered to the surface of the nasal mucosa by the drug delivery method of the inhalation of the nasal livestock, and the active ingredients of the drug powder are quickly absorbed by the rich capillaries on the surface of the mucosa to exert the curative effect. The nasal mucosa has the following advantages by taking a nasal livestock method as a drug delivery route: compared with the traditional oral administration and external administration methods, the method has the advantages that the administration route is novel, the use is convenient and fast, the curative effect is reliable, the side effect is less, the storage is convenient, the dosage and the time effect can be adjusted in real time according to the requirement, compared with the modern diversified dosage forms such as spray and other liquid dosage forms, the carrying is more convenient, the consumer is more acceptable, and the method completely meets the life requirements of modern people on time saving, fast rhythm and high efficiency. The nasal livestock drug enters systemic circulation through the inhalation of capillary vessels under the nasal mucosa, thereby reducing the degradation of gastrointestinal tract enzyme and acid and the decomposition effect of liver on the active ingredients of the drug, and fully exerting the comprehensive efficacy of the original drug; because the enzymatic activity of the mucous membrane surface is lower, the fine particles administered by the nasal livestock are adhered to the mucous membrane surface of the nasal cavity, the degradation time is prolonged, and the sustained release of the drug efficacy is facilitated.

The invention has the beneficial effects that:

the invention provides a traditional Chinese medicine composition for preventing and treating alopecia, which takes Szechwan Chinaberry fruit as a monarch drug, has bitter and cold property, enters liver, small intestine and bladder channels, and is used for soothing liver, promoting qi circulation and relieving pain; the ligusticum wallichii, the aloe and the asarum are used as ministerial drugs, and the ligusticum wallichii is pungent, warm, slightly sweet and enters liver and gallbladder channels to be used for promoting qi circulation and dispelling melancholy, dispelling wind-dryness and dampness, and activating blood and relieving pain; aloe is bitter and cold in nature, and can be used for killing bacteria, relieving inflammation, moistening skin, invigorating stomach, promoting excretion, tonifying heart, promoting blood circulation, enhancing immunity, promoting regeneration, and removing toxic substance; the asarum is pungent and spicy in flavor and numb tongue, warm in nature, enters heart, lung and kidney channels, and has the effects of expelling wind, dispelling cold, warming lung, promoting diuresis and inducing resuscitation; the monarch and ministerial medicines are compatible, and the mint, the divaricate saposhnikovia root and the borneol are added for assisting, so that the effects of relieving exterior syndrome and sweating, dispelling wind and removing dampness, and dispersing stagnated fire are achieved, and the effects of tonifying kidney and nourishing blood, dispelling wind and clearing heat, promoting qi circulation and resolving depression and invigorating blood circulation are achieved. The composition belongs to the medicine for astringing, tonifying qi, strengthening the exterior and being sweet and sour, and all components are matched with the exterior deficiency symptom of alopecia.

According to the modern theory of Chinese medicine meridian tropism, the medicine action is selectively attributed to certain viscera and meridians, and the traditional Chinese medicine thinks that the nose is the orifice of the lung, the qi of which goes upwards to the brain and descends to the lung, and the heart and the lung co-live in the triple energizer. Lung and kidney are homologous, and the lung qi fails to disperse and the yin and blood are deficient, and the failure of nourishment of the lung and kidney results in desquamation. The composition has good improving effect on alopecia areata, seborrheic alopecia, and symptomatic alopecia caused by neuropsychiatric factors, and accompanied scalp pruritus, dizziness, tinnitus, soreness of waist and knees, etc. In addition, the health-care wine has certain health-care and rehabilitation effects on normal physiological metabolism of skin and hair due to the action mechanisms of tonifying kidney, nourishing blood, dispelling wind, clearing heat, promoting qi circulation, relieving depression and activating blood circulation.

The preparation method of the traditional Chinese medicine composition for preventing and treating alopecia is simple in preparation process, only by grinding the raw materials into powder, the content of active ingredients in the raw materials is guaranteed to the maximum extent, loss is reduced, energy is saved, consumption is reduced, safety is high, and the traditional Chinese medicine composition is suitable for mass production in factories.

The invention provides a drug delivery method by nasal mucosa, which is characterized in that drug powder is adhered to the surface of the nasal mucosa by a drug delivery method of nasal livestock inhalation, and the active ingredients of the drug powder are rapidly absorbed by abundant microvessels on the surface of the mucosa to exert curative effect, thereby reducing the degradation of gastrointestinal tract enzyme and acid and the decomposition effect of liver on the active ingredients of the drug, and fully exerting the comprehensive efficacy of the original drug; because the enzymatic activity of the mucous membrane surface is lower, the fine particles administered by the nasal livestock are adhered to the mucous membrane surface of the nasal cavity, the degradation time is prolonged, and the sustained release of the drug efficacy is facilitated.

Detailed Description

The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. The reagents used are all conventional products which are commercially available.

Example 1:

a preparation method of a traditional Chinese medicine composition for preventing and treating alopecia comprises selecting 3g of rhizoma ligustici wallichii, 12 g of szechwan chinaberry fruit, 3g of asarum, 15 g of aloe, 3g of mint, 1 g of radix sileris and 0.1 g of borneol according to corresponding proportions, respectively drying at 10 ℃, mixing, grinding and sieving by a 100-mesh sieve to obtain finished product powder.

Example 2:

a preparation method of a traditional Chinese medicine composition for preventing and treating alopecia comprises selecting 20 g of rhizoma ligustici wallichii, 40 g of szechwan chinaberry fruit, 15 g of asarum, 45 g of aloe, 15 g of mint, 5 g of divaricate saposhnikovia root and 0.5 g of borneol according to corresponding proportions, respectively drying at 35 ℃, mixing, grinding and sieving by a 200-mesh sieve to obtain finished product powder.

Example 3:

a preparation method of a traditional Chinese medicine composition for preventing and treating alopecia comprises selecting 5 g of rhizoma ligustici wallichii, 20 g of szechwan chinaberry fruit, 5 g of asarum, 20 g of aloe, 4 g of mint, 2 g of radix sileris and 0.2 g of borneol according to corresponding proportions, respectively drying at 10 ℃, mixing, grinding and sieving by a 100-mesh sieve to obtain finished product powder.

Example 4:

a preparation method of a traditional Chinese medicine composition for preventing and treating alopecia comprises selecting 15 g of rhizoma ligustici wallichii, 30 g of szechwan chinaberry fruit, 10 g of asarum, 30 g of aloe, 10 g of mint, 4 g of divaricate saposhnikovia root and 0.3g of borneol according to corresponding proportions, respectively drying at 35 ℃, mixing, grinding and sieving by a 200-mesh sieve to obtain finished product powder.

Example 5:

a preparation method of a traditional Chinese medicine composition for preventing and treating alopecia comprises selecting 10 g of rhizoma ligustici wallichii, 35 g of szechwan chinaberry fruit, 8 g of asarum, 25 g of aloe, 8 g of mint, 3g of divaricate saposhnikovia root and 0.25 g of borneol according to corresponding proportions, respectively drying at 35 ℃, mixing, grinding and sieving by a 200-mesh sieve to obtain finished product powder.

Note that: in the using process, the phenomena of slight nasal obstruction, itching feeling of ants on the hairline of the forehead, dandruff increase at the affected part, scalp fever and the like of individual patients can occur, and the phenomena are all caused by overlong one-time sniffing time, accelerated blood circulation and over-rapid local capillary blood vessel congestion. The frequency and time of sniffing are reduced or the medicine is suspended, the symptoms are relieved and disappeared, and no sequela is left;

the pregnant women and the lactation period can be avoided;

the use of the special component in the prescription is avoided;

the nasal mucosa lesion damage inflammatory infection and the like are avoided.

Clinical cases:

patient 1: male, 26 years old, Wuxi city, government officer, 12 months and 21 days in 2019.

Clinical conditions: if the hair loss is found at about 2 cm above the head, the hair loss will be scattered at the dark spots, i.e. the broken ends of the remaining hair follicles. Patients complain about the pathological changes suddenly half a year ago, and the reasons are unknown. When the diagnosis is symptomatic alopecia, the sufferer is fond of smoking and alcohol, and the treatment is carried out by using the minoxidil tincture, so that the effect is not obvious.

Treatment methods and results: the powder of the Chinese medicinal composition prepared in example 5 was used in an amount of 10 g/bottle, and after one week, vellus hairs had emerged from the skin of the affected part. After 40 days, the vellus hairs became gray black, and the healing was reported.

Patient 2: women, 61 years old, Lanzhou city, retired and visited 24 days 11/2019.

Clinical conditions: patients complain about hair loss for more than half a year. The pillow is scattered after getting up in the morning. The medical history is examined without other causes of diseases, physical and chemical factors are excluded, and the causes are mostly caused by insufficient sleep and excessive fatigue. And diagnosing as symptomatic alopecia. Before treatment, various traditional Chinese medicine oral preparations and lotions have been used, and the effect is not obvious.

Treatment methods and results: by using the powder of the traditional Chinese medicine composition prepared in the example 5, 10 g/bottle of the powder can ensure that the alopecia symptom disappears when the patient is subjected to the double-visit after 20 days, and the patient does not relapse after two months.

Patient 3: women, 30 years old, Baoji City, national enterprise technician, visit 1 month and 2 days in 2020.

Clinical conditions: patients complain of alopecia especially in combing hair and washing hair in the morning. The patients with work fatigue and mental stress are usually examined. When the hair growth promoting liquid is used, the effect is not obvious.

Treatment methods and results: by using the powder of the Chinese medicinal composition prepared in the above example 5, 10 g/bottle, the symptoms of alopecia were remarkably relieved when the patient was asked for the next visit three weeks later.

Patient 4: for men, 35 years old, Beijing, in the establishment of the studio, the doctor visits 1 month and 16 days in 2020.

Clinical conditions: patients complain of hair loss. The past history of other diseases and cause of psychological cause are not found, and the pressure of entrepreneurship is too high, so that the sleep at night is less and the energy is insufficient in daytime. And diagnosing as symptomatic alopecia. Han Yong 9+9 was used before treatment, which is not good.

Treatment methods and results: the powder of the Chinese medicinal composition prepared in the above example 5, 10 g/bottle, had no alopecia symptom after 20 days of phone call follow-up.

Patient 5: men, 32 years old, Beijing, communications Engineers, visit 3, month, and 15 days 2020.

Clinical conditions: the right side of the top of the head is provided with an oval alopecia lesion of about 1.3 cm, the surface of the hair is bright, and the hair is scattered at the broken end of the hair follicle. The physician complains about the sudden pathological changes before one month of bathing, and the reasons are unknown. Acute alopecia areata is diagnosed. The health of the people is good, and the people do not have bad taste such as smoke, wine and the like. Some external traditional Chinese medicine lotion is used before treatment, and the effect is not good.

Treatment methods and results: the powder of the Chinese medicinal composition prepared in example 5 was used in an amount of 10 g/bottle, and the vellus hairs were born on the affected skin 20 days later. After two months, the patient followed up and reported that the vellus hair was gray black.

Patient 6: for men, 45 years old, Tongliao City, general prison, 3/month in 2020 and 18 days.

Clinical conditions: the etiology of this disease is mostly caused by work fatigue, sleep deficiency, excessive smoking and drinking and mental stress. And diagnosing as symptomatic alopecia. Before the doctor, products such as octopus 101 pilatory and Hanyong 9+9, etc. are used, all of which have poor curative effects.

Treatment methods and results: after 20 days, the patient complains that the alopecia has ceased when the patient rechecks the cable medicine, and the telephone follow-up is not recurrent after two months, using the powder prepared in example 5 above, 10 g/bottle.

The present invention is not limited to the above alternative embodiments, and any other products in various forms can be obtained by the present invention, and the present invention is within the protection scope of the present invention. The above embodiments should not be construed as limiting the scope of the present invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the above embodiments, or equivalent substitutions may be made to some or all of the technical features thereof, without departing from the scope of the present invention, and at the same time, such modifications or substitutions may not make the essence of the corresponding technical solutions depart from the scope of the embodiments of the present invention.

Claims

1. The traditional Chinese medicine composition for preventing and treating alopecia is characterized by being mainly prepared from the following raw materials in parts by mass:

2. The traditional Chinese medicine composition for preventing and treating alopecia according to claim 1, which is characterized by being mainly prepared from the following raw materials in parts by mass:

3. The traditional Chinese medicine composition for preventing and treating alopecia according to claim 2, which is characterized by being mainly prepared from the following raw materials in parts by mass:

4. A method for preparing the Chinese medicinal composition for preventing and treating alopecia according to any one of claims 1 to 3, wherein the method comprises selecting ligusticum wallichii, toosendan fruit, asarum, aloe, mint, radix sileris and borneol according to corresponding proportions, respectively drying, mixing, grinding and sieving to obtain a finished product.

5. The method for preparing a Chinese medicinal composition for preventing and treating alopecia according to claim 4, wherein the drying temperature is 10-35 ℃.

6. The method as claimed in claim 4, wherein the screening is performed with a 100-200 mesh screen.

7. The method for preparing a Chinese medicinal composition for preventing and treating alopecia according to claim 4, wherein the final product is in powder form.

8. The Chinese medicinal composition for preventing and treating alopecia according to any one of claims 1 to 3, wherein the Chinese medicinal composition is administered by nasal inhalation.

9. The composition of claim 8, wherein the composition is administered by applying the composition to the skin with fingers, placing the composition into the nostrils, and applying the composition to the mucous membrane.

10. The traditional Chinese medicine composition for preventing and treating alopecia according to claim 9, wherein the administration amount is 0.1-0.3 g/time.