CN113181326A - Aromatic external conditioning liquid medicine formula and preparation process thereof - Google Patents
Aromatic external conditioning liquid medicine formula and preparation process thereof Download PDFInfo
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Abstract
The invention relates to the technical field of conditioning liquid medicine, and discloses aromatic external conditioning liquid medicine which comprises the following raw materials in parts by weight: 35% of icestage essential oil, 5% of ginger root oil, 5% of frankincense oil, 5% of fennel oil, 2% of myrrh oil, 1% of rosemary leaf oil, 2% of camphor ice, 5% of cinnamon oil, 3% of corn kernel oil, 15% of white mustard seed essential oil, 2% of safflower essential oil, 5% of garden balsam seed essential oil, 1% of clove essential oil, 2% of white radish seed oil, 2% of camphor stock solution, 5% of chamomile essential oil, 2% of fructus psoraleae extract and 3% of lycopodium clavatum extract. The aromatic external conditioning liquid medicine formula and the preparation process thereof have the advantages that the compatibility of all the compositions is scientific, the medicine is selected to be fine, the medicine property is mild, no toxic or side effect is generated, the liquid medicine is aromatic liquid medicine, the disadvantages of heavy medicine taste and heavy alcohol taste in the external liquid are thoroughly overcome, the liquid medicine adopts a medicine ion introduction therapy, the local administration, the skin permeation, the bone penetration absorption and the focus point incision are realized, the effect is better and more stable, and the effect is quicker.
Description
Technical Field
The invention relates to the technical field of conditioning liquid medicine, in particular to an aromatic external conditioning liquid medicine formula and a preparation process thereof.
Background
The externally applied medicine is characterized in that the externally applied medicine is in the dosage forms of ointment, pellet, water, wine, powder, medicated thread (medicinal herbs) and the like, and is directly applied to an affected part, the application method comprises plaster application, coating, applying, mixing, fumigating, washing, soaking, bathing, eye dropping, ear pouring, nose dropping, throat blowing, fistula insertion of the medicinal herbs and the like, the externally applied medicine has the effects of detoxifying, swelling relieving, pus drawing out, removing putrefaction, flattening pterygium, granulation promoting, wound closing, hemostasis, disinsection, itching relieving, foaming and the like, and part of the medicine has certain functions; some medicines also have internal treatment effects of tonifying fire and strengthening yang, dispelling pathogenic wind and dredging collaterals, purging and removing stagnation, removing blood stasis and relieving pain, breaking knots and eliminating symptoms, eliminating phlegm and relieving asthma, relieving convulsion, preventing malaria, inducing resuscitation, and the like.
Along with the social development and the improvement of living standard, people pay more and more attention to health preservation, and modern people often can improve self health through some means of taking care of because work study pressure is big under most circumstances for a long time, lack the exercise, but present external use conditioning liquid medicine, traditional chinese medicine and alcohol taste are heavy, take effect slowly, and difficult operation leads to user's use to experience relatively poor.
Disclosure of Invention
Technical problem to be solved
Aiming at the defects of the prior art, the invention provides an aromatic external conditioning liquid medicine formula and a preparation process thereof, which have the advantages of no pungent smell, quick response, no pain and easy operation, and solve the problems of heavy traditional Chinese medicine and alcohol taste, slow response and difficult operation of the traditional external conditioning liquid medicine, and poor use experience of users.
(II) technical scheme
In order to realize the purposes of no pungent smell, quick response, no pain and easy operation, the invention provides the following technical scheme: an aromatic external conditioning liquid medicine comprises the following raw materials in parts by weight: 35% of iceberg essential oil, 5% of ginger root oil, 5% of frankincense oil, 5% of fennel oil, 2% of myrrh oil, 1% of rosemary leaf oil, 2% of camphor ice, 5% of cinnamon oil, 3% of corn kernel oil, 15% of white mustard seed essential oil, 2% of safflower essential oil, 5% of garden balsam seed essential oil, 1% of clove essential oil, 2% of white radish seed oil, 2% of camphor stock solution, 5% of chamomile essential oil, 1-4% of fructus psoraleae extract and 1-4% of lycopodium clavatum extract.
Preferably, the feed comprises the following raw materials in parts by weight: 35% of icestage essential oil, 5% of ginger root oil, 5% of frankincense oil, 5% of fennel oil, 2% of myrrh oil, 1% of rosemary leaf oil, 2% of camphor ice, 5% of cinnamon oil, 3% of corn kernel oil, 15% of white mustard seed essential oil, 2% of safflower essential oil, 5% of garden balsam seed essential oil, 1% of clove essential oil, 2% of white radish seed oil, 2% of camphor stock solution, 5% of chamomile essential oil, 2% of fructus psoraleae extract and 3% of lycopodium clavatum extract.
Preferably, the glacial acetic acid essential oil is prepared by crushing and sieving wormwood, putting the powder into a supercritical CO2 extraction device for extraction, wherein the extraction temperature is 35-40 ℃, the extraction pressure is 20-25MPa, the CO2 flow rate is 20g/min, the separation kettle temperature is 30 ℃, the operation is 90min, after the extraction is finished, washing with absolute ethyl alcohol, centrifuging, removing waxy components, removing moisture with anhydrous sodium sulfate, and decompressing the filtrate at 30 ℃ to obtain the glacial acetic acid essential oil.
Preferably, the mastic oil is prepared by steam distillation of gum resin exuded from trunk of Boswellia carterii belonging to family Burseraceae, wherein the distillation time is 4h and the distillation speed is 100 mL/h; the fennel oil is prepared by steaming and frying crushed fennel, extracting by using normal hexane and water, standing for layering, and separating and filtering an oil layer by a vacuum oil filter.
Preferably, the myrrh oil is prepared by steam distillation of myrrh oleoresin; the rosemary leaf oil is prepared by steam distillation, wherein the distillation time is 6h, and the distillation speed is 120 mL/h; the cinnamon oil is prepared by extracting cinnamon through supercritical carbon dioxide.
Preferably, the clove essential oil and the chamomile essential oil are both prepared by steam distillation, wherein the distillation time is 5 hours, and the distillation speed is 100 mL/h; the fructus psoraleae extract is prepared by extracting fructus psoraleae serving as a raw material, wherein the fructus psoraleae extract contains psoralen and isopsoralen, the water content of the fructus psoraleae extract is not more than 6.0%, the burning residue amount is not more than 1.0%, and the heavy metal content is not more than 0.01 ‰.
A preparation process of aromatic externally-used conditioning liquid medicine comprises the following steps:
1) taking the raw materials according to the specified weight proportion for later use, respectively injecting the essential oil of the ice platform, the ginger root, the frankincense, the anise oil, the myrrh oil, the rosemary leaf oil, the cinnamon oil, the corn kernel oil, the white mustard seed essential oil, the safflower essential oil, the garden balsam seed essential oil, the clove essential oil, the white radish seed oil, the camphor stock solution and the chamomile essential oil into different storage containers, forcing the various essential oils in the different storage containers to be synchronously sprayed into a mixing cavity of a sterilized mixing barrel along a spray nozzle in a mist shape through a high-pressure pump, fully colliding and mixing the various essential oils under the drive of a motor blade inside the mixing cavity, and after the essential oil is injected, controlling a system to close the motor and stop the rotation of the blade so as to obtain the mixed essential oil;
2) standing the mixed essential oil obtained in the step 1) for at least 30 minutes, then putting the rest camphor ice, the fructus psoraleae extract and the lycopodium clavatum extract into the mixed essential oil, and uniformly stirring at 10-20 ℃ to obtain mixed liquid medicine;
3) sterilizing the mixed liquid medicine obtained in the step 3) by ultraviolet rays with the wavelength of 200-290 nm, subpackaging the essential oil into bottles, and storing the bottles in a dark place at a low temperature to obtain the conditioning liquid medicine.
(III) advantageous effects
Compared with the prior art, the invention provides an aromatic external conditioning liquid medicine formula and a preparation process thereof, and the aromatic external conditioning liquid medicine formula has the following beneficial effects:
1. the aromatic external conditioning liquid medicine formula and the preparation process thereof have the advantages that through scientific compatibility of the compositions, the medicine is selected to be fine, the medicine property is mild, no toxic or side effect is generated, the liquid medicine is aromatic liquid medicine, the disadvantages of heavy medicine taste and heavy alcohol taste in the external liquid are thoroughly overcome, the liquid medicine adopts the medicine ion introduction therapy, local administration is realized, skin permeation is realized, bone penetration absorption is realized, the focus point is cut in, the effect is better and more stable, the effect is quicker to take effect, and due to the fact that the aromatic external conditioning liquid medicine is external liquid medicine, the medicine does not need to be taken and injected, and the operation is not needed, so that various pains of a body can be easily conditioned.
2. The aromatic external conditioning liquid medicine formula and the preparation process thereof are characterized in that more than ten aromatic Chinese herbal medicines for promoting blood circulation and removing blood stasis are subjected to compatibility and combination, so that pores can be opened quickly, cells of a human body can be activated, garbage dirt at the tip of hair follicles and capillary vessels can be cleaned, the functions of softening blood vessels and effectively improving the elasticity of blood vessel walls can be achieved, channels and collaterals blocked by the human body can be cleared quickly, the effect can be achieved within one minute, more than 20% of pain can be relieved within thirty minutes, clinical symptoms can disappear, almost no irritation, no red swelling, mild heat generation, long time, no skin injury and almost no anaphylactic reaction exist after the aromatic external conditioning liquid medicine formula is used.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The aromatic external conditioning liquid medicine in the embodiment comprises the following raw materials in parts by weight: 35% of icestage essential oil, 5% of ginger root oil, 5% of frankincense oil, 5% of fennel oil, 2% of myrrh oil, 1% of rosemary leaf oil, 2% of camphor ice, 5% of cinnamon oil, 3% of corn kernel oil, 15% of white mustard seed essential oil, 2% of safflower essential oil, 5% of garden balsam seed essential oil, 1% of clove essential oil, 2% of white radish seed oil, 2% of camphor stock solution, 5% of chamomile essential oil, 2% of fructus psoraleae extract and 3% of lycopodium clavatum extract.
The glacial acetic acid essential oil is prepared by pulverizing folium Artemisiae Argyi, sieving, extracting with supercritical CO2 at 35-40 deg.C under 20-25MPa and CO2 flow rate of 20g/min at 30 deg.C for 90min, washing with anhydrous ethanol, centrifuging, removing waxy components, removing water with anhydrous sodium sulfate, and reducing pressure at 30 deg.C.
Mastic oil is prepared by steam distilling gum resin exuded from trunk of Olibanum of Burseraceae for 4 hr at a distillation speed of 100mL/h, and has effects of regulating qi, promoting blood circulation, relieving pain, removing toxic substance, treating stagnation of qi and blood, pain of heart and abdomen, carbuncle, sore, toxic swelling, traumatic injury, dysmenorrhea, and puerperal blood stasis and pain; the anise oil is prepared by steaming and frying crushed fennel, extracting by using normal hexane and water, standing for layering, and separating and filtering an oil layer by a vacuum oil filter.
The myrrh oil is prepared by steam distillation of myrrh oleoresin; the rosemary leaf oil is prepared by steam distillation, wherein the distillation time is 6h, the distillation speed is 120mL/h, and the myrrh oil is used for treating chest and abdomen stasis pain, dysmenorrheal, amenorrhea, abdominal mass, traumatic injury, carbuncle swelling, sore and ulcer, intestinal abscess, conjunctival congestion and swelling pain, and has the effects of activating blood circulation to relieve pain, diminishing swelling, promoting granulation and the like; the cinnamon oil is prepared by extracting cinnamon through supercritical carbon dioxide, and has the effects of improving skin, losing weight, reducing body weight, relieving whole body muscle soreness, relieving dyspepsia and flatulence, promoting estrus, treating impotence and the like.
The clove essential oil and the chamomile essential oil are prepared by steam distillation, wherein the distillation time is 5h, the distillation speed is 100mL/h, the clove essential oil has a calming effect and can inhibit peripheral nerve excitation, and the chamomile essential oil can relieve anxiety, tension, anger and fear, so that people can relax and have tolerance and feel peaceful; the fructus Psoraleae extract is prepared by extracting fructus Psoraleae as raw material, and contains psoralen and isopsoralen, wherein the water content of fructus Psoraleae extract is not more than 6.0%, residue on ignition is not more than 1.0%, and heavy metal content is not more than 0.01 ‰.
Ginger root oil has effects of promoting blood circulation, dispelling cold, eliminating dampness, and inducing perspiration; the safflower essential oil has the functions of activating blood circulation, stimulating menstrual flow, dissipating blood stasis and relieving pain; the rosemary leaf oil has the effects of tranquilizing and restoring consciousness, has the curative effects on insomnia, palpitation, headache, dyspepsia and stomachache, and also has the effects of strengthening the heart, promoting metabolism, promoting blood circulation of peripheral blood vessels, enhancing attention, treating rheumatalgia, strengthening liver function, reducing blood sugar and the like.
A preparation process of aromatic externally-used conditioning liquid medicine comprises the following steps:
1) taking the raw materials according to the specified weight proportion for later use, respectively injecting the essential oil of the ice platform, the ginger root, the frankincense, the anise oil, the myrrh oil, the rosemary leaf oil, the cinnamon oil, the corn kernel oil, the white mustard seed essential oil, the safflower essential oil, the garden balsam seed essential oil, the clove essential oil, the white radish seed oil, the camphor stock solution and the chamomile essential oil into different storage containers, forcing the various essential oils in the different storage containers to be synchronously sprayed into a mixing cavity of a sterilized mixing barrel along a spray nozzle in a mist shape through a high-pressure pump, fully colliding and mixing the various essential oils under the drive of a motor blade inside the mixing cavity, and after the essential oil is injected, controlling a system to close the motor and stop the rotation of the blade so as to obtain the mixed essential oil;
2) standing the mixed essential oil obtained in the step 1) for at least 30 minutes, then putting the rest camphor ice, the fructus psoraleae extract and the lycopodium clavatum extract into the mixed essential oil, and uniformly stirring at 10-20 ℃ to obtain mixed liquid medicine;
3) sterilizing the mixed liquid medicine obtained in the step 3) by ultraviolet rays with the wavelength of 200-290 nm, subpackaging the essential oil into bottles, and storing the bottles in a dark place at a low temperature to obtain the conditioning liquid medicine.
The invention has the beneficial effects that:
1. the composition has scientific compatibility, fine medicine selection, mild medicine property and no toxic or side effect, the liquid medicine is aromatic liquid medicine, the disadvantages of heavy medicine taste and heavy alcohol taste in the external liquid are thoroughly overcome, so that various pains and various uncomfortable symptoms (such as soreness, numbness, sleepiness, swelling, pain, itching, tinea and various skin diseases) of a user gradually disappear in aromatic and warm fragrance, and the liquid medicine adopts a medicine ion introduction therapy, is locally administrated, is permeated through skin, is absorbed through bones, is incised at focus points, has no pain and no negative effect, is easy to master, is easy to copy, is easy to operate, has better and more stable effect and takes effect quickly, and can easily condition various pains of a body without taking medicines or injection or performing an operation due to the external liquid medicine.
2. Through carrying out the compatibility combination to more than ten kinds of aromatic blood circulation promoting blood stasis removing Chinese herbal medicine, make it can open the pore fast, activate human cell, clear up the rubbish dirt of hair follicle and capillary vessel tip, can play the blood vessel of softening, effectively improve the elastic function of vascular wall, can get through human occlusive main and collateral channels fast, can take effect within a minute, can make more than 20% pain reach clinical symptom disappearance about thirty minutes, use the back and hardly irritate, no red and swollen, it is mild to generate heat, the time lasts, do not harm skin, hardly there is anaphylactic reaction.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (7)
1. The aromatic external conditioning liquid medicine is characterized by comprising the following raw materials in parts by weight: 35% of iceberg essential oil, 5% of ginger root oil, 5% of frankincense oil, 5% of fennel oil, 2% of myrrh oil, 1% of rosemary leaf oil, 2% of camphor ice, 5% of cinnamon oil, 3% of corn kernel oil, 15% of white mustard seed essential oil, 2% of safflower essential oil, 5% of garden balsam seed essential oil, 1% of clove essential oil, 2% of white radish seed oil, 2% of camphor stock solution, 5% of chamomile essential oil, 1-4% of fructus psoraleae extract and 1-4% of lycopodium clavatum extract.
2. The aromatic external conditioning liquid medicine according to claim 1, characterized by comprising the following raw materials in parts by weight: 35% of icestage essential oil, 5% of ginger root oil, 5% of frankincense oil, 5% of fennel oil, 2% of myrrh oil, 1% of rosemary leaf oil, 2% of camphor ice, 5% of cinnamon oil, 3% of corn kernel oil, 15% of white mustard seed essential oil, 2% of safflower essential oil, 5% of garden balsam seed essential oil, 1% of clove essential oil, 2% of white radish seed oil, 2% of camphor stock solution, 5% of chamomile essential oil, 2% of fructus psoraleae extract and 3% of lycopodium clavatum extract.
3. The aromatic externally-applied conditioning medicine liquid as claimed in claim 1, wherein the glacial acetic acid essential oil is prepared by pulverizing and sieving folium artemisiae argyi, putting the powder into a supercritical CO2 extraction device for extraction, wherein the extraction temperature is 35-40 ℃, the extraction pressure is 20-25MPa, the CO2 flow rate is 20g/min, the separation kettle temperature is 30 ℃, the operation time is 90min, after the extraction is finished, washing with absolute ethyl alcohol, centrifuging, removing waxy components, removing moisture with anhydrous sodium sulfate, and decompressing the filtrate at 30 ℃ to obtain the glacial acetic acid essential oil.
4. The aromatic topical conditioning liquid medicine according to claim 1, wherein the mastic oil is prepared by steam distillation of gum resin exuded from trunk of mastic gum of family Burseraceae, wherein the distillation time is 4h and the distillation speed is 100 mL/h; the fennel oil is prepared by steaming and frying crushed fennel, extracting by using normal hexane and water, standing for layering, and separating and filtering an oil layer by a vacuum oil filter.
5. The fragrant external conditioning lotion of claim 1, wherein the myrrh oil is prepared by steam distillation of myrrh gum resin; the rosemary leaf oil is prepared by steam distillation, wherein the distillation time is 6h, and the distillation speed is 120 mL/h; the cinnamon oil is prepared by extracting cinnamon through supercritical carbon dioxide.
6. The aromatic external conditioning liquid medicine according to claim 1, characterized in that the clove essential oil and the chamomile essential oil are both prepared by steam distillation, wherein the distillation time is 5h, and the distillation speed is 100 mL/h; the fructus psoraleae extract is prepared by extracting fructus psoraleae serving as a raw material, wherein the fructus psoraleae extract contains psoralen and isopsoralen, the water content of the fructus psoraleae extract is not more than 6.0%, the burning residue amount is not more than 1.0%, and the heavy metal content is not more than 0.01 ‰.
7. A preparation process of aromatic external conditioning liquid medicine is characterized by comprising the following steps:
1) taking the raw materials according to the specified weight proportion for later use, respectively injecting the essential oil of the ice platform, the ginger root, the frankincense, the anise oil, the myrrh oil, the rosemary leaf oil, the cinnamon oil, the corn kernel oil, the white mustard seed essential oil, the safflower essential oil, the garden balsam seed essential oil, the clove essential oil, the white radish seed oil, the camphor stock solution and the chamomile essential oil into different storage containers, forcing the various essential oils in the different storage containers to be synchronously sprayed into a mixing cavity of a sterilized mixing barrel along a spray nozzle in a mist shape through a high-pressure pump, fully colliding and mixing the various essential oils under the drive of a motor blade inside the mixing cavity, and after the essential oil is injected, controlling a system to close the motor and stop the rotation of the blade so as to obtain the mixed essential oil;
2) standing the mixed essential oil obtained in the step 1) for at least 30 minutes, then putting the rest camphor ice, the fructus psoraleae extract and the lycopodium clavatum extract into the mixed essential oil, and uniformly stirring at 10-20 ℃ to obtain mixed liquid medicine;
3) sterilizing the mixed liquid medicine obtained in the step 3) by ultraviolet rays with the wavelength of 200-290 nm, subpackaging the essential oil into bottles, and storing the bottles in a dark place at a low temperature to obtain the conditioning liquid medicine.
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Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1718226A (en) * | 2005-05-09 | 2006-01-11 | 汪建国 | Medicine composition for treating leuconychia, and its prepn. method |
CN104491767A (en) * | 2014-08-18 | 2015-04-08 | 李学尧 | Chinese medicinal composition for relieving pain and preparation method thereof |
CN106214881A (en) * | 2016-08-19 | 2016-12-14 | 欧芳生物科技(上海)股份有限公司 | A kind of chest plentiful massage quintessence oil and preparation method thereof |
CN107982298A (en) * | 2017-12-19 | 2018-05-04 | 中国农业科学院烟草研究所 | The extracting method of wormwood essential oil and the application in terms of phytopathogen is suppressed |
CN108210867A (en) * | 2018-01-26 | 2018-06-29 | 中山市艾奥比生物科技有限公司 | A kind of palm moxibustion liquid for treating pain and preparation method thereof |
CN110339331A (en) * | 2019-08-07 | 2019-10-18 | 深圳市中科汉方科技有限公司 | A kind of plant is releived essential oil |
CN110403869A (en) * | 2019-08-21 | 2019-11-05 | 重庆珂蓝健康管理集团有限公司 | A kind of plant is releived composite essential oil and preparation method thereof |
-
2021
- 2021-05-06 CN CN202110488054.7A patent/CN113181326A/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1718226A (en) * | 2005-05-09 | 2006-01-11 | 汪建国 | Medicine composition for treating leuconychia, and its prepn. method |
CN104491767A (en) * | 2014-08-18 | 2015-04-08 | 李学尧 | Chinese medicinal composition for relieving pain and preparation method thereof |
CN106214881A (en) * | 2016-08-19 | 2016-12-14 | 欧芳生物科技(上海)股份有限公司 | A kind of chest plentiful massage quintessence oil and preparation method thereof |
CN107982298A (en) * | 2017-12-19 | 2018-05-04 | 中国农业科学院烟草研究所 | The extracting method of wormwood essential oil and the application in terms of phytopathogen is suppressed |
CN108210867A (en) * | 2018-01-26 | 2018-06-29 | 中山市艾奥比生物科技有限公司 | A kind of palm moxibustion liquid for treating pain and preparation method thereof |
CN110339331A (en) * | 2019-08-07 | 2019-10-18 | 深圳市中科汉方科技有限公司 | A kind of plant is releived essential oil |
CN110403869A (en) * | 2019-08-21 | 2019-11-05 | 重庆珂蓝健康管理集团有限公司 | A kind of plant is releived composite essential oil and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
杨炳蔚,等: "精油及其在芳香疗法中的应用", 《中国化妆品(行业)》 * |
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