CN1131712C - 初乳肽及其用途 - Google Patents

初乳肽及其用途 Download PDF

Info

Publication number
CN1131712C
CN1131712C CN97198535A CN97198535A CN1131712C CN 1131712 C CN1131712 C CN 1131712C CN 97198535 A CN97198535 A CN 97198535A CN 97198535 A CN97198535 A CN 97198535A CN 1131712 C CN1131712 C CN 1131712C
Authority
CN
China
Prior art keywords
colostrum
peptides
colostrinin
medicine
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN97198535A
Other languages
English (en)
Chinese (zh)
Other versions
CN1238782A (zh
Inventor
马林·雅努什
约瑟夫·利索夫斯基
安娜·杜博夫斯卡－因格洛特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ludwig Herzfeld Institute of Immunology and
Ludwig Hilsfeld Institute Of Immunology And Experimental Therapeutics Polish Academy Of Sciences
Original Assignee
Ludwig Herzfeld Institute of Immunology and
Ludwig Hilsfeld Institute Of Immunology And Experimental Therapeutics Polish Academy Of Sciences
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Herzfeld Institute of Immunology and, Ludwig Hilsfeld Institute Of Immunology And Experimental Therapeutics Polish Academy Of Sciences filed Critical Ludwig Herzfeld Institute of Immunology and
Publication of CN1238782A publication Critical patent/CN1238782A/zh
Application granted granted Critical
Publication of CN1131712C publication Critical patent/CN1131712C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/324—Foods, ingredients or supplements having a functional effect on health having an effect on the immune system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Psychology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
CN97198535A 1996-10-03 1997-10-03 初乳肽及其用途 Expired - Fee Related CN1131712C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PLP.316416 1996-10-03
PL96316416A PL185442B1 (pl) 1996-10-03 1996-10-03 Środek farmaceutyczny o działaniu immunologicznym i psychotropowym, jego postać terapeutyczna oraz zastosowanie

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA031466095A Division CN1535722A (zh) 1996-10-03 1997-10-03 初乳肽及其用途

Publications (2)

Publication Number Publication Date
CN1238782A CN1238782A (zh) 1999-12-15
CN1131712C true CN1131712C (zh) 2003-12-24

Family

ID=20068412

Family Applications (2)

Application Number Title Priority Date Filing Date
CN97198535A Expired - Fee Related CN1131712C (zh) 1996-10-03 1997-10-03 初乳肽及其用途
CNA031466095A Pending CN1535722A (zh) 1996-10-03 1997-10-03 初乳肽及其用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CNA031466095A Pending CN1535722A (zh) 1996-10-03 1997-10-03 初乳肽及其用途

Country Status (18)

Country Link
US (2) US6852700B1 (enExample)
EP (1) EP0932623A1 (enExample)
JP (2) JP2001501929A (enExample)
KR (2) KR100508764B1 (enExample)
CN (2) CN1131712C (enExample)
AR (1) AR013612A1 (enExample)
AU (1) AU4565197A (enExample)
BR (1) BR9712259A (enExample)
CA (1) CA2266859C (enExample)
CZ (1) CZ298215B6 (enExample)
GB (1) GB2333453B (enExample)
HU (1) HUP9904368A3 (enExample)
IL (1) IL129211A (enExample)
PL (1) PL185442B1 (enExample)
RU (1) RU2217152C2 (enExample)
TR (1) TR199901022T2 (enExample)
WO (1) WO1998014473A1 (enExample)
ZA (1) ZA978885B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL185442B1 (pl) 1996-10-03 2003-05-30 Georgiades Biotech Ltd Środek farmaceutyczny o działaniu immunologicznym i psychotropowym, jego postać terapeutyczna oraz zastosowanie
ID26730A (id) 1998-05-27 2001-02-01 Gemma Biotechnology Ltd Induksi protein-protein dan peptida-peptida antibiotik oleh lait/scd14-protein
MXPA00012399A (es) * 1998-06-10 2003-07-14 Albert B Crum Complememnto nutricional profilactico y terapeutico para la creacion y mantenimiento de microflora intestinal protectora de la salud y mejoramiento del sistema inmunologico.
GB9813031D0 (en) * 1998-06-16 1998-08-12 Regen Biotech Limited Dietary supplement
GB9912852D0 (en) * 1999-06-02 1999-08-04 Regen Therapeutics Plc Peptides
US6852685B1 (en) * 1999-08-17 2005-02-08 Board Of Regents, The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof to promote neuronal cell differentiation
WO2001012650A2 (en) 1999-08-17 2001-02-22 The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof as oxidative stress regulators
DE60036638T2 (de) * 1999-08-17 2008-02-21 The University Of Texas System, Austin Verwendung von colostrinin, dessen peptidbestandteile und deren analoga zur förderung der neuronalen zelldifferenzierung
US7119064B2 (en) * 1999-08-17 2006-10-10 Board Of Regents, The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof as modulators of intracellular signaling molecules
EP1224217A4 (en) * 1999-08-17 2006-05-24 Univ Texas USE OF COLOSTRININE, ITS CONSTITUENT PEPTIDES AND ITS ANALOGUES FOR ACTIVATING CYTOKINES
US6903068B1 (en) * 1999-08-17 2005-06-07 Board Of Regents, The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof for inducing cytokines
GB0001825D0 (en) * 2000-01-26 2000-03-22 Regen Therapeutics Plc Peptides
WO2002013849A1 (en) * 2000-08-17 2002-02-21 The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof for inducing cytokines
WO2002013850A1 (en) * 2000-08-17 2002-02-21 The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof as oxidative stress regulators
WO2002013851A1 (en) * 2000-08-17 2002-02-21 The University Of Texas System Use of colostrinin, constituent peptides thereof, and analogs thereof to promote neural cell differentiation
GB0029777D0 (en) 2000-12-06 2001-01-17 Regen Therapeutics Plc Peptides
HUP0200172A2 (hu) * 2002-01-15 2003-11-28 András Bertha Eljárás tumorellenes hatóanyag kinyerésére
EP1567551A4 (en) * 2002-10-22 2008-03-12 Univ Texas COLOSTRININE AND PEPTIDES THEREOF AS MODULATORS OF INTRACELLULAR SIGNALING MOLECULES AND INHIBITORS OF APOPTOSIS
US20070161780A1 (en) * 2003-03-11 2007-07-12 Regen Therapeutics Plc Purification of peptides from colostrum
CN1313487C (zh) * 2003-06-10 2007-05-02 天津商学院 具有抗菌作用的免疫活性肽（Trpi）
WO2005041680A2 (en) * 2003-11-03 2005-05-12 Advanced Protein Systems A novel colostral fractionation process
EP1723951A1 (en) * 2005-04-21 2006-11-22 N.V. Nutricia Nutritional supplement with oligosaccharides for a category of HIV patients
US20070212367A1 (en) * 2006-03-13 2007-09-13 Keech Andrew M Novel immunologically active peptide fragments of a proline-rich polypeptide isolated from colostral mammalian fluids for treatment of viral and non-viral diseases or diseased conditions
GB2436328A (en) * 2006-03-22 2007-09-26 Regen Therapeutics Plc Peptide derived from colostrinin
US20110098216A1 (en) * 2009-10-22 2011-04-28 Regen Therapeutics Plc Therapeutic uses of colostrinin
ITMI20111460A1 (it) * 2011-07-29 2013-01-30 Bionest Ltd Composizioni per la terapia adiuvante dell'anoressia comprendenti anticorpi, fattori di crescita e citochine isolati dal colostro dei mammiferi
DK2797609T3 (en) 2011-12-30 2017-01-09 Innomed S A COMBINING growth factors, cytokines, anti-bacterial / ANTIVIRALS FACTORS STEM CELL-STIMULATING FACTORS, complement C3A / C4A, immunoglobulins, and chemotactic factors
RU2645082C2 (ru) 2011-12-30 2018-02-15 Инномед С.А. Комбинация факторов роста, цитокинов, антибактериальных/антивирусных факторов, факторов стволовых клеток, белков комплемента с3а/с4а и хемотаксических факторов
ITMI20112433A1 (it) * 2011-12-30 2013-07-01 Bionest Ltd Composizioni per la terapia orale adiuvante dell'anoressia comprendenti anticorpi, antibatterici, fattori di crescita e citochine
GB201205856D0 (en) 2012-04-02 2012-05-16 Randall Jeremy A P Food supplement to support brain function
PL235821B1 (pl) * 2014-11-04 2020-11-02 Geo Poland Spolka Z Ograniczona Odpowiedzialnoscia Wysokoprolinowy kompleks peptydowy do zastosowania w profilaktyce i wspomaganiu leczenia zaburzeń i stanów wymagających podwyższania i/lub modulacji poziomu neurotropowego czynnika pochodzenia mózgowego jako oznaczonego w osoczu krwi biomarkera i zawierający go preparat
CN107408214B (zh) 2015-01-30 2021-07-09 惠普发展公司，有限责任合伙企业 M进制循环编码
WO2020176637A1 (en) 2019-02-26 2020-09-03 Pantheryx, Inc. Compositions for management of disorders of the gastrointestinal tract

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE90569T1 (de) 1988-04-19 1993-07-15 Biotest Pharma Gmbh Praeparat mit antikoerperaktivitaet und breitem wirkungsspektrum, daraus bestehende oder diese enthaltende mittel und deren verwendung zur behandlung von bakteriell oder toxin-bedingten erkrankungen und zur bekaempfung von protozoen.
JPH05163160A (ja) * 1991-12-13 1993-06-29 Snow Brand Milk Prod Co Ltd 免疫低下に伴う感染症の予防及び治療用栄養剤
JP3174611B2 (ja) * 1992-02-28 2001-06-11 明治乳業株式会社 免疫賦活組成物
US5645834A (en) 1992-08-28 1997-07-08 Immuno-Dynamics, Inc. Method and product for treating failure of passive transfer and improving milk production in bovine species
GB9318611D0 (en) * 1993-09-08 1993-10-27 Sandoz Nutrition Ltd Improvements in or relating to organic compounds
DE4337654C2 (de) 1993-11-04 1996-08-08 Biotest Pharma Gmbh Verwendung boviner Kolostralmilch von nicht mit Viren hyperimmunisierten Tieren als Leberschutzpräparat
JP4112021B2 (ja) * 1994-02-16 2008-07-02 明治乳業株式会社 乳酸菌を用いた免疫賦活剤
RU2062109C1 (ru) * 1994-11-28 1996-06-20 Товарищество с ограниченной ответственностью "Старк" Способ получения иммунного препарата
WO1997005884A1 (en) 1995-08-07 1997-02-20 New England Medical Center Hospitals, Inc. Infant formula and infant formula additives
DE19619990A1 (de) 1996-05-17 1997-11-20 Charlotte Adler Verfahren zur Herstellung von Kolostralmilchprodukten sowie deren Verwendung
PL185442B1 (pl) 1996-10-03 2003-05-30 Georgiades Biotech Ltd Środek farmaceutyczny o działaniu immunologicznym i psychotropowym, jego postać terapeutyczna oraz zastosowanie

Also Published As

Publication number Publication date
JP2008174561A (ja) 2008-07-31
KR100508764B1 (ko) 2005-08-17
CZ298215B6 (cs) 2007-07-25
RU2217152C2 (ru) 2003-11-27
GB9908331D0 (en) 1999-06-09
GB2333453B (en) 2001-05-30
CN1535722A (zh) 2004-10-13
EP0932623A1 (en) 1999-08-04
KR20000048886A (ko) 2000-07-25
PL185442B1 (pl) 2003-05-30
GB2333453A (en) 1999-07-28
IL129211A0 (en) 2000-02-17
ZA978885B (en) 1999-07-26
PL316416A1 (en) 1998-04-14
CA2266859C (en) 2012-05-08
WO1998014473A1 (en) 1998-04-09
GB2333453A8 (en) 2000-11-27
KR20050046766A (ko) 2005-05-18
TR199901022T2 (xx) 1999-07-21
US6852700B1 (en) 2005-02-08
BR9712259A (pt) 2000-01-25
HUP9904368A2 (hu) 2000-06-28
AR013612A1 (es) 2001-01-10
CN1238782A (zh) 1999-12-15
CA2266859A1 (en) 1998-04-09
IL129211A (en) 2004-08-31
JP2001501929A (ja) 2001-02-13
AU4565197A (en) 1998-04-24
US20050152985A1 (en) 2005-07-14
HUP9904368A3 (en) 2000-07-28
CZ114999A3 (cs) 2000-06-14

Similar Documents

Publication Publication Date Title
CN1131712C (zh) 初乳肽及其用途
CA1336398C (en) Method for reducing side effects of cancer therapy
JPH10509955A (ja) 二次性免疫不全症の治療法
CA2171281C (en) Immunomodulating compositions from bile
US6447808B2 (en) Growth-promoting agent
FR2537436A1 (fr) Procede de regulation de l'appetit et de l'efficacite de l'utilisation des aliments utilisant de l'interferon
JP5247429B2 (ja) カゼイン由来ペプチドを含む医薬組成物及びその使用方法
CN1634987A (zh) 一种脾多肽提取物、其制备方法及其用途
US9249188B2 (en) Mammalian colostrum derived nanopeptides for broadspectrum viral and recurrent infections with a method of isolation thereof
CN1168499C (zh) 使粘液的粘度最佳化并且刺激肠功能的药物
AU761148B2 (en) Colostrinin, and uses thereof
GB2352176A (en) Colostrinin and uses thereof
MXPA99003108A (en) Colostrinin, and uses thereof
PL195627B1 (pl) Zastosowania kolostryniny, kompozycje farmaceutyczne do leczenia przewlekłych chorób ośrodkowego układu nerwowego lub immunostymulacji i zastosowanie nonapeptydu
RU2119330C1 (ru) Свечи

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20031224

Termination date: 20131003