CN1131535A - Multifunctional vaginal sponge - Google Patents

Multifunctional vaginal sponge Download PDF

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Publication number
CN1131535A
CN1131535A CN 95102894 CN95102894A CN1131535A CN 1131535 A CN1131535 A CN 1131535A CN 95102894 CN95102894 CN 95102894 CN 95102894 A CN95102894 A CN 95102894A CN 1131535 A CN1131535 A CN 1131535A
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China
Prior art keywords
vaginal sponge
iodine
medicinal liquid
content
amount
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CN 95102894
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Chinese (zh)
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李克亮
吴炳彪
李宏伟
赵香圃
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Individual
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Individual
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Priority to CN 95102894 priority Critical patent/CN1131535A/en
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A multifunctional vaginal sponge for contraception and preventing and curing venereal disease and gynopathies with high effect features that Np-9, iodoform, hibitane and domiphen, or the liquior extracted from flavescent sophora root, stemona root, cnidium root and motherwort, or their mixture are adsorbed by the sponge.

Description

Multifunctional vaginal sponge
The present invention relates to a kind of medicine that adsorbed, be used to the vaginal sponge of preventing and curing diseases or practising contraception.
WHO estimates annually to have 2.5 hundred million or the new patient of more sexually transmitted disease (STD), and wherein trichomoniasis 1.2 hundred million, chlamydia 5,000 ten thousand, human reproduction's device papillomavirus 3,000 ten thousand, gonorrhea 2,500 ten thousand, genital herpes 2,000 ten thousand, syphilis 3,500,000, chancroid 2,000,000; The island is grand among the WHO Secretary General points out: " sexually transmitted disease (STD); comprise acquired immune deficiency syndrome (AIDS) has become a kind of important epidemic diseases in the world, if people do not change its sexual behaviour; or do not carry out a kind of new effective control ruleization immediately, and the mortality rate of sexually transmitted disease (STD) can be higher.”
Over nearly 20 years, global pelvic infection disease significantly increases, and dangerous maximum 15-39 year women, having infected this sick women has 20% will recur approximately again.Various gynaecopathias, as cervical erosion, the acute and chronic vaginitis is all because of disturbing numerous women.
WHO proposes: " by 2000, allow the whole world everybody enjoy health care " target, allow people at physiology, spiritual and social each side is in a kind of state of complete health, allows people all have good reproduction, the ability that fertility is regulated and enjoying is lived.Allow people in pregnancy, childbirth, baby deposit words, succeed in the g and D aspect.
For realizing above-mentioned target, especial manufacture of the present invention multifunctional vaginal sponge, will be in contraception, prevent and treat sexually transmitted disease (STD) and the gynaecopathia aspect plays a role.
The vaginal sponge that the U.S. began to develop in 1976, nineteen eighty-three obtains drugs approved by FDA, and commodity be called " Today ", show the retail of can having write out a prescription of the U.S. and Britain, and it includes N p-9 spermicides because of its effective ingredient is single, only can be used for contraception, and its shape make it pick and place difficulty thereby have influenced applying of it.
The utility model patent of declaring by people such as Li Hongwei, the patent No. is 95205930.4 to disclose five kinds of vaginal sponges, its structure difference, function is different, they are discharged the carrier of medicine as the present invention, adsorb various medicine respectively, will be in contraception, prevent and treat sexually transmitted disease (STD), play a role on the treatment gynaecopathia.Its mechanism of action has three aspects: 1, simple physical barriers effect, can make sperm, pathogenic bacteria, virus can't enter vagina, uterus, or on be advanced into other position of uterine cavity and cause a disease; 2, adsorption can be adsorbed on seminal fluid or pathogenic bacteria virus in the sponge, can abandon during taking-up in external; 3, the different pharmaceutical in the sponge is by slowly discharging, but spermicide or prevent and treat sexually transmitted disease (STD) or the treatment gynaecopathia.
The present invention is compared with the prior art: 1, the support shapes difference of the absorption medicine that uses of the present invention, the function difference is convenient to again pick and place, and has adsorbed N pAfter-9, can guarantee the success rate of practising contraception; 2, the adsorbed medicine of the present invention can be prevented and treated sexually transmitted disease (STD) or have the gynopathic effect of treatment concurrently, and they are formed compound recipe, and its effect is better; 3, many Chinese medicine extraction liquid are used for the treatment of sexually transmitted disease (STD), and gynaecopathia often adopts the washing vagina method, medicine is short in the disease sites retention time like this, and promptly trouble is inconvenient again in flushing repeatedly, and medicine is adsorbed in the vaginal sponge, can slowly discharge, drug treating time is prolonged; 4, in the Chinese medicine and western medicine mixture absorption vaginal sponge, drug effect can be improved, chemical sproof generation can be prevented again.
Below be prescription percentage composition of the present invention (weight):
Prescription one (100 vaginal sponge content of dispersion)
Nonoxynolum (N p-9) 80-120g
Povidone iodine (available iodine) 0.001-8.0g
Distilled water is an amount of
With N p-9 and povidone iodine add successively in an amount of distilled water, fully just obtained can be for the medicinal liquid of vaginal sponge absorption usefulness in dissolving.
Prescription two (100 vaginal sponge content of dispersion)
Povidone iodine (available iodine) 0.01-8.0g
Chlorhexidine acetate 0-50g
Domiphen bromide 0-50g
Medical alcohol is an amount of
Distilled water is an amount of
Chlorhexidine acetate is dissolved in an amount of medical alcohol, standby.Povidone iodine added in an amount of distilled water dissolve, select again to add chlorhexidine acetate or domiphen bromide, fully dissolve and form medicinal liquid.Be adsorbed onto in the vaginal sponge.
Prescription three (100 vaginal sponge content of dispersion)
Radix Sophorae Flavescentis 750-1250g
Fructus Cnidii 375-625g
Radix Stemonae 375-625g
Herba Leonuri 375-625g
Nonoxynolum 0-100g
Chlorhexidine acetate 0-50g
Domiphen bromide 0-50g
Povidone iodine (available iodine) 0-8.0g
Medical alcohol is an amount of
Distilled water is an amount of
With Radix Sophorae Flavescentis, Fructus Cnidii, the Radix Stemonae, Herba Leonuri adds water, and medicine and water weight ratio are 1: 2, soaked 4-6 hour, decocting 0.5-2 hour, filter, concentrating and obtaining extracting solution is 1/5th of amount of water; Select adding a certain again, or certain several Western medicine, the gained medicinal liquid is for the usefulness of vaginal sponge absorption.
Povidone iodine described in above-mentioned three prescriptions can be provided by following substances: povidon iodine volt, polyethoxy ethanol povidone iodine, polyvinyl alcohol povidone iodine, nonoxynolum povidone iodine.
Processing technology: be illustrated in conjunction with the accompanying drawings.
One, medicinal liquid preparation: it is an amount of to measure distilled water: take by weighing various raw material of Chinese medicine by above-mentioned formula proportion and add in the distilled water successively, through merceration, hot shears, filtration, the concentrated Chinese medicine extraction liquid that obtains, select povidone iodine, chlorhexidine acetate, nonoxynolum, any one or a few stirring of domiphen bromide that it is fully dissolved; Behind the assay, adsorb medicinal liquid, packing back warehouse-in with vaginal sponge.Chinese medicine extraction has only been saved in the preparation of prescription one, two.
Two, absorption: according to using the object choice difformity, the vaginal sponge of different size is quantitatively adsorbed medicinal liquid under pressure control;
Three, encapsulation: will adsorb in the vaginal sponge dress plastic bag or blister plastic packaging of medicinal liquid sealing.
Accompanying drawing is the concrete work flow sketch map of multifunctional vaginal sponge of the present invention.
Using method:
The multifunctional vaginal sponge that has adsorbed soup picked and placeed more conveniently than former product, purposes is more extensive, and function is more, better effects if, and it is as follows that it specifically picks and places method:
Put into method:
1, will hand-wash only, from sealing bag, take out vaginal sponge.
2, pinch vaginal sponge with thumb and forefinger, make belt hang.
3, get half crouch, the fork both legs, separately the both sides labia is put into introitus with sponge.
4, up push away gently with one or two fingers, push the vagina deep, be close to uterine neck and get final product.
Removing method:
1, finger inserts vagina, touches belt, hooks with finger tip.
2, lightly, lentamente vaginal sponge is hauled out, abandon in waste receptacle.
Consumption: contraception: 1/time, took out in 24 hours.
Prevent and cure diseases: 1/time 1-2 times/day or follow the doctor's advice
Embodiment 1
Prescription one
Nonoxynolum (N p-9) 100g
Povidon iodine volt (containing available iodine 10%) 50mg
Distilled water 1000ml
Above-mentioned medicine is added in the 1000ml water successively, stir, after the dissolving, evenly be adsorbed in the type vaginal sponge of palace, 100 tops.Make 10 examples that a child's Mr. and Mrs are arranged, the age is in 25-40 year, 10 vaginal sponges of every couple of Mr. and Mrs, sexual intercourse in three days once, the contraception success rate is 100%.
Embodiment 2
Prescription two
Povidon iodine volt (containing available iodine 10%) 2.0g
Chlorhexidine acetate 0.5g
Medical alcohol 50ml
Distilled water 950ml
Chlorhexidine acetate is dissolved in earlier in the medical alcohol, adds distilled water, add the povidon iodine volt at last, stir and make its dissolving, evenly be adsorbed in 100 excellent type vaginal sponges.Two routine gonorrhea patients put into vagina under instructing, every day 2 times, each 1, (12) back checks that the gonorrhea diplococcus killing rate is respectively 99% and 94%, and is evident in efficacy to use a week.
Embodiment 3
Prescription three
Radix Sophorae Flavescentis 1000g
Fructus Cnidii 500g
Radix Stemonae 500g
Herba Leonuri 500g
Povidon iodine volt 1.g
(containing available iodine 10%)
Distilled water 500ml
Four flavor Chinese medicines are added in the 5000ml water, soaked 4 hours, heat was fried in shallow oil 2 hours, filtered, and was concentrated to the 1000ml extracting solution and added povidon iodine volt 1.0g, after the dissolving, evenly was adsorbed onto in 100 bullet cut vaginal sponges, used for two routine vaginitis patients.One next, once a day, 6 days is a course of treatment, all cure two courses of treatment.

Claims (5)

1, is used for contraception, prevents and treats the multifunctional vaginal sponge of sexually transmitted disease (STD) and control gynaecopathia, it is characterized in that with medical latex or medical polyurethane being that material is made vaginal sponge, behind the absorption medicinal liquid, and become this product.
2, according to claim 1, the medicinal liquid of vaginal sponge absorption is characterized in that its effective ingredient of said medicinal liquid and content are:
Nonoxynolum (N p-9) 80-120g
Povidone iodine (available iodine) 0.001~8.0g
Distilled water is an amount of
(100 vaginal sponge content of dispersion)
3, the medicinal liquid according to claim 1, that vaginal sponge is adsorbed is characterized in that its effective ingredient of said medicinal liquid and content are:
Povidone iodine (available iodine) 0.01-8.0g
Chlorhexidine acetate 0-50g
Domiphen bromide 0-50g
The medical essence of spilling is an amount of
Distilled water is an amount of
(100 vaginal sponge content of dispersion)
4, according to claim 1, the medicinal liquid of vaginal sponge absorption is characterized in that its effective ingredient of said medicinal liquid and content are:
Radix Sophorae Flavescentis 750~1250g
Fructus Cnidii 375~625g
The Radix Stemonae 375~625g
Herba Leonuri 375~625g
Nonoxynolum 0~100g
Chlorhexidine acetate 0~50g
Domiphen bromide 0~50g
Povidone iodine (available iodine) 0~8.0g
Medical alcohol is an amount of
Distilled water is an amount of
(100 vaginal sponge content of dispersion)
5, according to povidone iodine described in claim 2,3,4 prescriptions, it is characterized by the povidon iodine volt, polyethoxy ethanol povidone iodine, polyvinyl alcohol povidone iodine, nonoxynolum povidone iodine.
CN 95102894 1995-03-22 1995-03-22 Multifunctional vaginal sponge Pending CN1131535A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 95102894 CN1131535A (en) 1995-03-22 1995-03-22 Multifunctional vaginal sponge

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 95102894 CN1131535A (en) 1995-03-22 1995-03-22 Multifunctional vaginal sponge

Publications (1)

Publication Number Publication Date
CN1131535A true CN1131535A (en) 1996-09-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 95102894 Pending CN1131535A (en) 1995-03-22 1995-03-22 Multifunctional vaginal sponge

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062739C (en) * 1997-06-12 2001-03-07 武汉迪普生物技术有限公司 Medicine for preventing sexual disease
CN1086915C (en) * 1999-04-22 2002-07-03 钱建民 Mucous membrane cleaning disinfectant and its producing technology
CN101249084B (en) * 2008-03-18 2011-09-21 上海麟翔生物技术有限公司 Disinfection composing prescription of preventability transmitted diseases
CN103768469A (en) * 2012-10-23 2014-05-07 葛继云 Traditional Chinese medicine composition for treating gynecological inflammation, preparation method and application thereof
CN103988849A (en) * 2014-05-21 2014-08-20 德州安捷高科消毒制品有限公司 Process for preparing compound iodine disinfectant
WO2020133136A1 (en) * 2018-12-26 2020-07-02 赵春梅 Catheter drug type tampon for treating vaginitis and preparation method therefor

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1062739C (en) * 1997-06-12 2001-03-07 武汉迪普生物技术有限公司 Medicine for preventing sexual disease
CN1086915C (en) * 1999-04-22 2002-07-03 钱建民 Mucous membrane cleaning disinfectant and its producing technology
CN101249084B (en) * 2008-03-18 2011-09-21 上海麟翔生物技术有限公司 Disinfection composing prescription of preventability transmitted diseases
CN103768469A (en) * 2012-10-23 2014-05-07 葛继云 Traditional Chinese medicine composition for treating gynecological inflammation, preparation method and application thereof
CN103988849A (en) * 2014-05-21 2014-08-20 德州安捷高科消毒制品有限公司 Process for preparing compound iodine disinfectant
WO2020133136A1 (en) * 2018-12-26 2020-07-02 赵春梅 Catheter drug type tampon for treating vaginitis and preparation method therefor

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