CN1943666A - A Chinese/western compound medicine for treatment of and preventing women's colpitis - Google Patents
A Chinese/western compound medicine for treatment of and preventing women's colpitis Download PDFInfo
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- CN1943666A CN1943666A CN 200510021818 CN200510021818A CN1943666A CN 1943666 A CN1943666 A CN 1943666A CN 200510021818 CN200510021818 CN 200510021818 CN 200510021818 A CN200510021818 A CN 200510021818A CN 1943666 A CN1943666 A CN 1943666A
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Abstract
This invention provides a Chinese/western compound medicine for treatment of and preventing women's colpitis. Say it in detail is It provides a medicine that is prepared by combining the Chinese medical ingredients of kuhseng, Chinese corktree bark, fructus cnidii, cortex dictamni, pepper, borneol, menthol with the western medicine of Domiphen or chlorhexidine acetate which is used for sterilizing.This medicine has the efficacy of clearing heat and promoting diuresis, destroying parasites and relieving itching, restraining and sterilizing, suitable for treating and preventing colpitis including bacteroidal colpitis, colpitis mycotic, trichomonal vaginitis, non-specific colpitis and vulva itching.
Description
Technical field the present invention relates to a kind of colpitic Chinese medicine and western medicine compound medicine that has clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization effect, is used for the treatment of and prevents.Relate to a kind of Chinese and Western compound recipe patent medicine preparation made from Chinese herbal medicine and chemical drugs compound recipe particularly.Belong to pharmaceutical sanitary field.
The background technology vaginitis is the modal vaginal infection disease of child-bearing period women.Vaginitis comprises bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis.It is reported that in healthy women, colpitic sickness rate is up to 18.9%.The vaginitis clinical symptoms mainly shows as vaginal secretions and increases with foul smell, pruritus vulvae, and cause that cervix uteri, body of uterus infect and inflammatory pelvic disease.For this kind disease, motherland's traditional medicine thinks that female vagina belongs to damp-heat type pudendal pruritus, comprises infusorian property, colpitis mycotica.Disease is seen: the pudendum flushing, and swelling, the pain of very then itching, profuse leukorrhea, yellow skin such as pus, or be foam water from washing rice sample or bean curd slag specimen, its gas is stench, red tongue, yellow and greasy fur, soft and rapid pulse.China's traditional medicine adopts the Chinese medicine heat clearing and damp drying more, and killing parasites for relieving itching is treated.Modern Western learning adopts that the chemical drugs sterilization is antibiotic treats and prevent more.
Chinese patent (application number CN95112794.2) discloses a kind of sterilizing liquid Keyanshu for woman, it by Folium Artemisiae Argyi, Cortex Phellodendri, Fructus Cnidii, Radix Et Rhizoma Rhei, Rhizoma Atractylodis, etc. be main Chinese medicine ingredients, compound recipe is with chemical drugs domiphen bromide, chlorhexidine acetate, and is aided with Borneolum Syntheticum, Mentholum.Its weak point is weak, the heat clearing and damp drying dampness removing deficiency of parasite killing in the drug matching flavour of a drug, domiphen bromide and chlorhexidine acetate share influence and reduce its drug effect, its weak point only is also that from disinfection composing, from disease etiology and pathogenesis prescription, this patent application is not a disinfectant solution.
We based on Chinese medical theory to vaginitis, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pruritus vulvae the disease due to illness understanding and the Therapeutic Principle of machine, and in conjunction with modern medical theory, reuse Radix Sophorae Flavescentis and with Cortex Phellodendri, Fructus Cnidii, Pericarpium Zanthoxyli, Cortex Dictamni compatibility to strengthen its heat clearing and damp drying dampness removing, eliminating fire and detoxication, killing parasites for relieving itching function, to carry out the prescription screening with chemical bacteriostasis and sterilization preparation again, invent and a kind ofly be used for the treatment of and prevent colpitic Chinese medicine and chemical drugs compound medicine.
Summary of the invention the object of the invention is to provide a kind of colpitic Chinese medicine and western medicine compound medicine that has clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization effect, is used for the treatment of and prevents.
Another purpose of the present invention is that said medicine is made acceptable external and vagina medicinal thing carrier format on the pharmaceutics, comprises lotion, gel, suppository, vagina effervescence, vagina soft capsule.
Solution of the present invention is based on Chinese medical theory and modern medical theory vaginitis is comprised the understanding and the Therapeutic Principle of bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus pathogenic mechanism, and screening, prescription form.
Medicine of the present invention is made (consumption is a weight portion) by following materials of weight proportions:
Radix Sophorae Flavescentis 40-80 Cortex Phellodendri 40-80 Fructus Cnidii 10-50 Cortex Dictamni 10-50 Pericarpium Zanthoxyli 10-30
Borneolum Syntheticum 0.5-2 Mentholum 0.5-2 domiphen bromide 0.5-2
The better weight proportion of raw material is:
Radix Sophorae Flavescentis 50-70 Cortex Phellodendri 50-70 Fructus Cnidii 20-40 Cortex Dictamni 20-40 Pericarpium Zanthoxyli 15-25
Borneolum Syntheticum 0.8-1.5 Mentholum 0.8-1.5 domiphen bromide 0.8-1.5
The optimum weight proportioning of raw material is:
Radix Sophorae Flavescentis 60 Cortex Phellodendris 60 Fructus Cnidiis 30 Cortex Dictamni 30 Pericarpium Zanthoxylies 20 Borneolum Syntheticums 1
Mentholum 1 domiphen bromide 1
Above-mentioned clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization pharmaceutical composition can adopt the pharmaceutics technology to make acceptable external and vagina medicinal thing carrier format on the pharmaceuticss such as lotion, gel, suppository, vagina effervescence, vagina soft capsule.
Preparation method of the present invention can be to get Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Pericarpium Zanthoxyli to carry out percolation with ethanol, collects percolate Borneolum Syntheticum, Mentholum, domiphen bromide are added, and stirs and makes dissolving, mix homogeneously, solution for standby; Residue decocts with water, and filters, and filtrate and the merging of percolation solution are mixed,, add water to full dose, fill promptly gets vagina or external-use lotion.
Preparation method of the present invention can also be that Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Pericarpium Zanthoxyli carry out percolation with ethanol, collects percolate, reclaims ethanol, concentrates standby; Residue decocts with water, filtration, and filtrate concentrates the back and is mixed with the merging of percolation concentrated solution, and adding Borneolum Syntheticum, Mentholum, domiphen bromide stir and make dissolving, and mix homogeneously obtains drug extract, and extractum is carried out the molding preparation by following different formulation methods:
A: the thing extractum of getting it filled, add suppository base, stirring and evenly mixing is irritated mould, promptly gets vaginal suppository.
B: the thing extractum of getting it filled, add gel-type vehicle, stirring and evenly mixing, fill promptly gets vagina gel.
C: the thing extractum of getting it filled, fill promptly get the vagina soft capsule agent in soft capsule shell.
D: the thing extractum of getting it filled, drying obtains the drug extract powder, mixes with the effervescent tablet auxiliary element, and tabletting promptly gets vagina effervescence.
The present invention has clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization effect, is suitable for the treatment and the prevention of vaginitis, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus especially.
The present invention makes with following materials of weight proportions:
Radix Sophorae Flavescentis 40-80 Cortex Phellodendri 40-80 Fructus Cnidii 10-50 Cortex Dictamni 10-50 Pericarpium Zanthoxyli 10-30
Borneolum Syntheticum 0.5-2 Mentholum 0.5-2 chlorhexidine acetate 0.5-2
The better weight proportion of each raw material is:
Radix Sophorae Flavescentis 50-70 Cortex Phellodendri 50-70 Fructus Cnidii 20-40 Cortex Dictamni 20-40 Pericarpium Zanthoxyli 15-25
Borneolum Syntheticum 0.8-1.5 Mentholum 0.8-1.5 chlorhexidine acetate 0.8-1.5
The optimum weight proportioning of each raw material is:
Radix Sophorae Flavescentis 60 Cortex Phellodendris 60 Fructus Cnidiis 30 Cortex Dictamni 30 Pericarpium Zanthoxylies 20
Borneolum Syntheticum 1 Mentholum 1 chlorhexidine acetate 1
With the Chinese medicine and western medicine compound medicine of above-mentioned prescription, adopt the pharmaceutics technology to make acceptable external and vagina medicinal thing carrier format on the pharmaceuticss such as lotion, gel, suppository, vagina effervescence, vagina soft capsule.
Preparation method of the present invention can be to get Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Pericarpium Zanthoxyli to carry out percolation with ethanol, reclaims ethanol, solution for standby; Residue decocts with water, and filters, and filtrate and the merging of percolation solution are mixed, and adding Borneolum Syntheticum, Mentholum, chlorhexidine acetate stir and make dissolving, and mix homogeneously adds water to full dose, and fill promptly gets Chinese medicine and western medicine compound recipe medicine vagina or external-use lotion.
Preparation method of the present invention can also be that Radix Sophorae Flavescentis, Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Pericarpium Zanthoxyli carry out percolation with ethanol, reclaims ethanol, concentrates standby; Residue decocts with water, and filters, and filtrate and the merging of percolation solution are mixed, and are concentrated into thick paste, and adding Borneolum Syntheticum, Mentholum, chlorhexidine acetate stir and make dissolving, and mix homogeneously obtains drug extract, and extractum is carried out the molding preparation by following different formulation methods:
A: the thing extractum of getting it filled, add suppository base, stirring and evenly mixing is irritated mould, promptly gets vaginal suppository.
B: the thing extractum of getting it filled, add gel-type vehicle, stirring and evenly mixing, fill promptly gets vagina gel.
C: the thing extractum of getting it filled, fill promptly get the vagina soft capsule agent in soft capsule shell.
D: the thing extractum of getting it filled, drying obtains the drug extract powder, mixes with the effervescent tablet auxiliary element, and tabletting promptly gets vagina effervescence.
Of the present inventionly be used for the treatment of and prevent vaginitis, comprise being used for the treatment of and preventing vaginitis, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus.
Further elaborate the present invention below in conjunction with embodiment.
The specific embodiment
Embodiment one
Take by weighing raw material by following proportioning:
Radix Sophorae Flavescentis 600g Cortex Phellodendri 600g Fructus Cnidii 300g Cortex Dictamni 300g Pericarpium Zanthoxyli 200g
Borneolum Syntheticum 10g Mentholum 10g domiphen bromide 10g
Preparation method is as follows:
Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Radix Sophorae Flavescentis, Pericarpium Zanthoxyli carry out percolation with ethanol, receive the agent percolate, and Borneolum Syntheticum, Mentholum, domiphen bromide are added, and stir and make dissolving, obtain the percolation solution for standby; Residue decocts with water, and filters, and filtrate and percolation solution merge, and mix homogeneously adds water to 10000ml, and fill makes Chinese medicine and western medicine compound external-use lotion or vaginadouche agent.External of the present invention or washing vagina, 2-4 time on the one.
The present invention has clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization effect, is suitable for the treatment and the prevention of vaginitis, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and vaginal pruritus especially.
Embodiment two:
Take by weighing raw material by following proportioning:
Radix Sophorae Flavescentis 600g Cortex Phellodendri 600g Fructus Cnidii 300g Cortex Dictamni 300g Pericarpium Zanthoxyli 200g
Borneolum Syntheticum 10g Mentholum 10g chlorhexidine acetate 10g
Preparation method is as follows:
Preparation method of the present invention can be to get Cortex Phellodendri, Fructus Cnidii, Cortex Dictamni, Pericarpium Zanthoxyli to carry out percolation with ethanol, collects percolate, and Borneolum Syntheticum, Mentholum, chlorhexidine acetate are added, and stirs and makes dissolving, mix homogeneously, percolation solution for standby; Residue decocts with water, and filters, and filtrate and the merging of percolation solution are mixed, and add water to 10000ml, and fill promptly gets Chinese medicine and western medicine compound recipe vagina or external-use lotion.External of the present invention or washing vagina, 2-4 time on the one, a 50-100ml.
Setting forth good effect chemical drugs domiphen bromide of the present invention below is surface activity broad-spectrum antiviral, wide-spectrum bactericide.Chlorhexidine acetate is a Cidex-7, has stronger broad-spectrum antibacterial bactericidal action, is particularly suitable for the disinfection of skin and mucosa.Radix Sophorae Flavescentis and Cortex Phellodendri, the external of Fructus Cnidii compatibility have heat clearing and damp drying, eliminating fire and detoxication, killing parasites for relieving itching, bacteriostasis and sterilization effect; Pericarpium Zanthoxyli, Cortex Dictamni, Fructus Cnidii compatibility dispeiling pathogenic wind and removing dampness, killing parasites for relieving itching; Compound recipe strengthens bacteriostasis and sterilization effect of the present invention to have surface activity broad-spectrum antiviral, wide-spectrum bactericide chemical drugs domiphen bromide or chlorhexidine acetate; All medicines share and make prescription have the effect of clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization, are aided with Borneolum Syntheticum again, Mentholum makes skin and mucosa produce refrigerant comfort.So the present invention has clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization effect, is applicable to that vaginitis comprises the treatment and the prevention of bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus.The patient takes like a shot especially.
Chinese medicine and western medicine compound recipe of the present invention has clearing away heat-damp and promoting diuresis, killing parasites for relieving itching, bacteriostasis and sterilization effect, is suitable for the treatment and the prevention of vaginitis, bacterial vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus especially.
Claims (10)
1. one kind is used for the treatment of and prevents colpitic Chinese medicine and western medicine compound medicine, it is characterized in that making with following materials of weight proportions:
Radix Sophorae Flavescentis 40-80 Cortex Phellodendri 40-80 Fructus Cnidii 10-50 Cortex Dictamni 10-50
Pericarpium Zanthoxyli 10-30 Borneolum Syntheticum 0.5-2 Mentholum 0.5-2 domiphen bromide 0.5-2.
2. as claimed in claim 1ly a kind ofly be used for the treatment of and prevent colpitic Chinese medicine and western medicine compound medicine, it is characterized in that the better weight proportion of described raw material is:
Radix Sophorae Flavescentis 50-70 Cortex Phellodendri 50-70 Fructus Cnidii 20-40 Cortex Dictamni 20-40
Pericarpium Zanthoxyli 15-25 Borneolum Syntheticum 0.8-1.5 Mentholum 0.8-1.5 domiphen bromide 0.8-1.5.
3. as claimed in claim 1ly a kind ofly be used for the treatment of and prevent colpitic Chinese medicine and western medicine compound medicine, it is characterized in that the optimum weight proportioning of described raw material is:
Radix Sophorae Flavescentis 60 Cortex Phellodendris 60 Fructus Cnidiis 30 Cortex Dictamni 30
Pericarpium Zanthoxyli 20 Borneolum Syntheticums 1 Mentholum 1 domiphen bromide 1.
4. describedly a kind ofly be used for the treatment of and prevent colpitic Chinese medicine and western medicine compound medicine as claim 1 and 2 and 3, it is characterized in that the medicine of above-mentioned prescription made acceptable external and vagina medicinal thing carrier format on the pharmaceuticss such as lotion, gel, suppository, vagina effervescence, vagina soft capsule, vaginal tablet.
5. as claimed in claim 4ly a kind ofly be used for the treatment of and prevent colpitic Chinese medicine and western medicine compound medicine, it is characterized in that being used for vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus.
6. one kind is used for the treatment of and prevents colpitic Chinese medicine and western medicine compound medicine, it is characterized in that making with following materials of weight proportions:
Radix Sophorae Flavescentis 40-80 Cortex Phellodendri 40-80 Fructus Cnidii 10-50 Cortex Dictamni 10-50 Pericarpium Zanthoxyli 10-30
Borneolum Syntheticum 0.5-2 Mentholum 0.5-2 chlorhexidine acetate 0.5-2.
7. as claimed in claim 6ly be used for the treatment of and prevent colpitic Chinese medicine and western medicine compound medicine, it is characterized in that the better weight proportion of described raw material is:
Radix Sophorae Flavescentis 50-70 Cortex Phellodendri 50-70 Fructus Cnidii 20-40 Cortex Dictamni 20-40 Pericarpium Zanthoxyli 15-25
Borneolum Syntheticum 0.8-1.5 Mentholum 0.8-1.5 chlorhexidine acetate 0.8-1.5.
8. claim 6 is described is used to be used for the treatment of and prevents colpitic Chinese medicine and western medicine compound medicine, it is characterized in that the optimum weight proportioning of described raw material is:
Radix Sophorae Flavescentis 60 Cortex Phellodendris 60 Fructus Cnidiis 30 Cortex Dictamni 30
Pericarpium Zanthoxyli 20 Borneolum Syntheticums 1 Mentholum 1 chlorhexidine acetate 1.
9. describedly be used for the treatment of and prevent colpitic Chinese medicine and western medicine compound medicine as claim 6 and 7 and 8, it is characterized in that the medicine of above-mentioned prescription made acceptable external and vagina medicinal thing carrier format on the pharmaceuticss such as lotion, gel, suppository, vagina effervescence, vagina soft capsule, vaginal tablet.
10. as being used for the treatment of of stating of claim 6 with prevent colpitic Chinese medicine and western medicine compound medicine, it is characterized in that being used for vaginitis, colpitis mycotica, trichomonal vaginitis, nonspecific vaginitis and pudendal pruritus.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 200510021818 CN1943666A (en) | 2005-10-08 | 2005-10-08 | A Chinese/western compound medicine for treatment of and preventing women's colpitis |
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| CN 200510021818 CN1943666A (en) | 2005-10-08 | 2005-10-08 | A Chinese/western compound medicine for treatment of and preventing women's colpitis |
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Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101244187B (en) * | 2008-02-02 | 2010-06-09 | 温先敏 | Suppository for treating gynaecologic disease |
| CN101816741A (en) * | 2010-05-10 | 2010-09-01 | 贵州金桥药业有限公司 | Vagina cleaning product for women and preparation method thereof |
| CN102283934A (en) * | 2010-06-17 | 2011-12-21 | 茅燕菊 | Drug lotion |
| CN102579654A (en) * | 2012-03-26 | 2012-07-18 | 杨长辉 | Anti-bacteria medicine for protecting and cleaning human body vagina and preparation method thereof |
| CN102846858A (en) * | 2012-04-10 | 2013-01-02 | 江西青春康源制药有限公司 | Antibacterial pharmaceutical composition |
| CN103386076A (en) * | 2012-05-07 | 2013-11-13 | 四川九峰天然药业股份有限公司 | Mucosa nursing antibacterial gel composition and application thereof |
| CN104138445A (en) * | 2013-05-10 | 2014-11-12 | 艾白媛 | Traditional Chinese medicinal external lotion for treating leukoplakia vulvae |
| CN104274751A (en) * | 2014-10-22 | 2015-01-14 | 吉林省正和药业集团股份有限公司 | Vagifresh lotion |
| CN104906066A (en) * | 2015-06-18 | 2015-09-16 | 青岛海之星生物科技有限公司 | Lincomycin hydrochloride compound vaginal effervescent tablets and preparation method thereof |
| CN106266541A (en) * | 2016-08-31 | 2017-01-04 | 刘岚 | A kind of Chinese medicine and western medicine compound preparation treating nonspecific vaginitis and preparation method |
| CN108553608A (en) * | 2018-05-30 | 2018-09-21 | 武汉润禾生物医药有限公司 | A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch |
| CN110123986A (en) * | 2019-05-17 | 2019-08-16 | 湖南天大生物科技股份有限公司 | A kind of composition improving microecology in vaginas |
| WO2020123559A1 (en) * | 2018-12-11 | 2020-06-18 | Glyciome, Llc | Topical, isotonic compositions for genital use |
| CN111821399A (en) * | 2020-09-07 | 2020-10-27 | 三泉(泉州)生物科技有限公司 | Herbal antibacterial cream |
-
2005
- 2005-10-08 CN CN 200510021818 patent/CN1943666A/en active Pending
Cited By (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244187B (en) * | 2008-02-02 | 2010-06-09 | 温先敏 | Suppository for treating gynaecologic disease |
| CN101816741A (en) * | 2010-05-10 | 2010-09-01 | 贵州金桥药业有限公司 | Vagina cleaning product for women and preparation method thereof |
| CN102283934A (en) * | 2010-06-17 | 2011-12-21 | 茅燕菊 | Drug lotion |
| CN102579654A (en) * | 2012-03-26 | 2012-07-18 | 杨长辉 | Anti-bacteria medicine for protecting and cleaning human body vagina and preparation method thereof |
| CN102846858A (en) * | 2012-04-10 | 2013-01-02 | 江西青春康源制药有限公司 | Antibacterial pharmaceutical composition |
| CN103386076A (en) * | 2012-05-07 | 2013-11-13 | 四川九峰天然药业股份有限公司 | Mucosa nursing antibacterial gel composition and application thereof |
| CN103386076B (en) * | 2012-05-07 | 2018-01-12 | 四川九峰天然药业股份有限公司 | A kind of mucomembranous nursing antibacterial gel composition and its application |
| CN104138445A (en) * | 2013-05-10 | 2014-11-12 | 艾白媛 | Traditional Chinese medicinal external lotion for treating leukoplakia vulvae |
| CN104274751B (en) * | 2014-10-22 | 2017-08-22 | 吉林省正和药业集团股份有限公司 | Cleaning agent for bathing pudenda |
| CN104274751A (en) * | 2014-10-22 | 2015-01-14 | 吉林省正和药业集团股份有限公司 | Vagifresh lotion |
| CN104906066A (en) * | 2015-06-18 | 2015-09-16 | 青岛海之星生物科技有限公司 | Lincomycin hydrochloride compound vaginal effervescent tablets and preparation method thereof |
| CN106266541A (en) * | 2016-08-31 | 2017-01-04 | 刘岚 | A kind of Chinese medicine and western medicine compound preparation treating nonspecific vaginitis and preparation method |
| CN108553608A (en) * | 2018-05-30 | 2018-09-21 | 武汉润禾生物医药有限公司 | A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch |
| WO2020123559A1 (en) * | 2018-12-11 | 2020-06-18 | Glyciome, Llc | Topical, isotonic compositions for genital use |
| CN113613733A (en) * | 2018-12-11 | 2021-11-05 | 葛莱赛欧米有限责任公司 | Topical, isotonic compositions for genital use |
| CN110123986A (en) * | 2019-05-17 | 2019-08-16 | 湖南天大生物科技股份有限公司 | A kind of composition improving microecology in vaginas |
| CN110123986B (en) * | 2019-05-17 | 2021-05-18 | 湖南天大生物科技股份有限公司 | Composition for improving vaginal microecology |
| CN111821399A (en) * | 2020-09-07 | 2020-10-27 | 三泉(泉州)生物科技有限公司 | Herbal antibacterial cream |
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