CN108553608A - A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch - Google Patents
A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch Download PDFInfo
- Publication number
- CN108553608A CN108553608A CN201810535981.8A CN201810535981A CN108553608A CN 108553608 A CN108553608 A CN 108553608A CN 201810535981 A CN201810535981 A CN 201810535981A CN 108553608 A CN108553608 A CN 108553608A
- Authority
- CN
- China
- Prior art keywords
- parts
- acetic acid
- dermatitis
- itch
- vulval
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of bacteriostatic gels for treating vulval dermatitis itch, belong to treatment vulval dermatitis itch technical field of pharmaceuticals；Wherein the parts by weight of each component are 35 parts of frutus cnidii, 24 parts of kuh-seng, 8 10 parts of folium artemisiae argyi, 69 parts of honeysuckle, 46 parts of cordate houttuynia, 25 parts of the tuber of stemona, 26 parts of angelica tail, 14 parts of garden burnet, 14 parts of duckweed, 25 parts of the root of Chinese clematis, 14 parts of coptis root, 13 parts of Radix Angelicae Pubescentis, 20 40 parts of castor oil, 24 parts of acetic acid chlorhexidine；It is this product heat-clearing wind-dispelling, promoting blood circulation and removing blood stasis antipruritic, there is preferable bacterio static itching-relieving to act on pruritus vulvue, clinical efficacy is notable, controls difficulty in relapse after healing, has no toxic side effect.
Description
Technical field
The present invention relates to a kind of gels and preparation method thereof, and in particular to a kind of bacteriostatic gel for treating vulval dermatitis itch
And preparation method thereof, belong to treatment vulval dermatitis itch technical field of pharmaceuticals.
Background technology
Pruritus vulvue is a kind of symptom caused by the various different lesions of vulva, is labia, anus, scrotum this itch at three
General designation.But can also betide the completely normal person of vulva, when itch aggravates, patient more feel restless so that influence life and
Work.Pruritus vulvue multidigit can also involve the long-term scratchings of the skin lesions area such as labia majora, perineum even crissum in clitoris, nymphae can
There is scratch, scab or secondary epifolliculitis.Pruritus vulvue is not a kind of self-existent disease, it is often many kinds of diseases
One symptom, but what reason may also be can not find sometimes, only simple itch.But it but occurs whenever and wherever possible, has itched
It makes one fidgety, can't fall asleep, the suffering felt embarrassed to mention is brought to women.Private parts can be safeguarded by washing vulva with Feminine care solution daily
Self-cleaning function solves the unknown cause of pruritus vulvue.Chinese medicine thinks, ailment said due to cold or exposure, damp evil, heat evil, the deficiency of blood, worm are excessive etc. for pathogenic master
Want reason, treatment should be with clearing damp, clearing heat and detoxicating, enriching the blood to restore normal menstruation, promoting blood circulation and removing blood stasis for principle, to reach the antipruritic work(of righting of getting rid of evils
Effect.
The local cause that pruritus vulvue generates, common are：1, most common local cause has a leucorrhea increasing, especially by
Vaginitis and nonspecific vaginitis caused by trichomonad or mycotic infection, a large amount of abnormal leukorrhea stimulation vulva being discharged
Portion makes vulva itch；If 2, placing certain dripping of irritant drugs with disinfection liquid rinsing vulva, vagina or intravaginal, cause medicine
Object allergy, chemical irritation cause pudendum part skin allergy or dermatitis occur, and vulva is caused to be itched.Vulva is matched with Ph4 weak acid
Square Feminine care solution cleaning can more safeguard private parts self-cleaning function；3, menstrual period do not pay attention to sanitation and hygiene, and the sanitary napkin used is unclean
Or it is irritant, cause menses or vaginal fluid to lodge in external genital for a long time, or usually wear chemical fibre underpants and gas permeability
Bad panty hose makes external genital, with hot environment, often vulva can be caused scratchy often in wet；4, somebody is through common alkalinity
Stronger soap or liquor potassic permanganate clean vulva, and skin of vulva is caused to dry, and lack grease and itch；5, enterobiasis is suffered from
People, since pinworm is usually climbed out of by anus, and stimulate perianal and external genital, and cause itch, attached most importance to especially with night, very
It sleeps to influence；6, can not only be caused not by eczema of vulva, neurodermatitis, atrophic sclerosis moss, vulval dermatitis etc.
With the itch of degree, at the same pudendum part skin may also have it is different degrees of bleach, atrophy or the variation thickened；7, carcinoma of vulva
Advanced symptoms also have a pruritus vulvue, somebody in itch for many years after, carcinoma of vulva has occurred.
Treating various types of vaginitis at present has leucorrhea increasing, frequent micturition, urgent urination, the symptom of odynuria, vulva different
The itch of degree, scorching hot or feeling of pain, acute stage, can be with fevers.
Invention content
The purpose of the present invention proposes a kind of dissipate to solve the problems, such as the treatment of current vulval dermatitis pruritus dermatopathy
Wind Eradicates is wet, desinsection, anti-inflammatory, antipruritic, the bacteriostatic gel for the treatment vulval dermatitis itch having no toxic side effect.To achieve the above object,
The present invention adopts the following technical scheme that：
A kind of bacteriostatic gel for treating vulval dermatitis itch, the weight proportion of material composition are as follows：
3-5 parts of frutus cnidii, 2-4 parts of kuh-seng, 8-10 parts of folium artemisiae argyi, 6-9 parts of honeysuckle, 4-6 parts of cordate houttuynia, 2-5 parts of the tuber of stemona, angelica tail 2-
6 parts, 1-4 parts of garden burnet, 1-4 parts of duckweed, 2-5 parts of the root of Chinese clematis, 1-4 parts of coptis root, 1-3 parts of Radix Angelicae Pubescentis, 20-40 parts of castor oil, acetic acid chlorine
2-4 parts are determined.
3-4 parts of frutus cnidii, 9-10 parts of folium artemisiae argyi, 6-7 parts of honeysuckle, 5-6 parts of cordate houttuynia, 2-3 parts of the tuber of stemona, is returned at 2-3 parts of kuh-seng
5-6 parts of tail, 1-2 parts of garden burnet, 3-4 parts of duckweed, 2-4 parts of the root of Chinese clematis, 3-4 parts of coptis root, 1-2 parts of Radix Angelicae Pubescentis, 20-30 parts of castor oil, vinegar
Sour chlorhexidine 3-4 parts.
4-5 parts of frutus cnidii, 8-9 parts of folium artemisiae argyi, 7-9 parts of honeysuckle, 4-5 parts of cordate houttuynia, 4-5 parts of the tuber of stemona, is returned at 3-4 parts of kuh-seng
2-4 parts of tail, 3-4 parts of garden burnet, 1-3 parts of duckweed, 3-5 parts of the root of Chinese clematis, 1-3 parts of coptis root, 2-3 parts of Radix Angelicae Pubescentis, 30-40 parts of castor oil, vinegar
Sour chlorhexidine 2-3 parts.
4-5 parts of frutus cnidii, 9-10 parts of folium artemisiae argyi, 7-8 parts of honeysuckle, 5-6 parts of cordate houttuynia, 3-5 parts of the tuber of stemona, is returned at 3-4 parts of kuh-seng
2-4 parts of tail, 3-4 parts of garden burnet, 2-3 parts of duckweed, 3-4 parts of the root of Chinese clematis, 2-3 parts of coptis root, 2-3 parts of Radix Angelicae Pubescentis, 25-35 parts of castor oil, vinegar
Sour chlorhexidine 2-3 parts.
A kind of bacteriostatic gel preparation method for treating vulval dermatitis itch, includes the following steps：
（1）Chinese medicine material is ground into fine powder with pulverizer, the purified water that 20 times of amounts of medicinal material total weight are added decocts 2-3h, mistake
Filtrate is collected in filter；The water that 8-15 times of medicinal material weight is measured is added in the dregs of a decoction again and decocts 1-2h, filtering collects filtrate, by two
Secondary filtrate merges, and is concentrated into the medicinal extract of semisolid；
（2）Medicinal extract is freeze-dried, 200 mesh sieve is crushed, obtains Chinese medicinal powder；
（3）1.5 are pressed in 75% ethyl alcohol:1 takes acetic acid chlorhexidine to be mixed with Chinese medicinal powder, is heated in 70~80 DEG C of water-baths, melts
Change, stir evenly, after fully emulsified, stirring and gradually cooling stir evenly, and obtain clear gel, as this product.
The pharmacological property of the raw materials used in the present invention is as follows：
Frutus cnidii eliminating dampness, wind-dispelling, desinsection；
Kuh-seng heat-clearing and damp-drying drug, desinsection is antipruritic, antibacterial, anti-inflammatory, antiallergy；
Folium artemisiae argyi warming channel for arresting bleeding, eliminating cold to stop pain；External application removing dampness to stop itchin；
Honeysuckle is sweet in flavor cold in nature, clearing heat and detoxicating；
Cordate houttuynia is clearing heat and detoxicating, inducing diuresis to remove edema；
Tuber of stemona moistening lung to lower qi cough-relieving, desinsection；
Angelica tail enriching the blood and tonifying qi；
It is garden burnet blood-stanching and blood-cooling, clearing heat and detoxicating；
Duckweed clearing away heat and promoting diuresis cures mainly the fever of table heresy, measles, wind-heat pain rash, pruitus；
Root of Chinese clematis wind-damp dispelling, degrading the channel, the bone that disappears stalk；
Coptis root heat-clearing and damp-drying drug, Qinghuo Jiedu；
Radix Angelicae Pubescentis dispelling wind and eliminating dampness, arthritis analgesic；
Castor oil purging intense heat, except steaming, detoxification sore treatment；
Chlorhexidine acetate is also Robenidine Roripa, chlorhexidine acetate, Chlorhexidine, double benzyl chloride chlorhexidine, for cation
Surfactant, has a broad antifungal spectrum have killing effect to most Grain-positives and negative bacteria, also effective to Pseudomonas aeruginosa, use
In operation remote holder, skin, planing surface and sterilization of instruments.
The advantages of the present invention are：This bacteriostatic gel is with doctor trained in Western medicine based on modern Chinese medicine to pathogenesis of acne mechanism
Understanding and principle of reatment, selected Chinese and western medical raw material is formulated using unique formula, and when treatment, external application takes this ointment
It is applied to affected part in right amount, once a day or twice, a month as a course for the treatment of；It takes effect within usual one month, can cure within 1~6 month；Only
Effect of itching is good, controls difficulty in relapse after healing, has no toxic side effect.
Specific implementation mode
Product of the present invention is further described below in conjunction with the embodiment of the present invention, the description of embodiment is only for ease of understanding
With with the application of the invention, rather than to the limitation protected of the present invention.Unless stated otherwise, the % in the present invention is mass percent；
Unless stated otherwise, preparation process carries out under room temperature, normal pressure state；Unless stated otherwise, the present invention in use reagent, side
Method and equipment are the art conventional reagent, method and apparatus；Unless stated otherwise, in the present invention experimental condition that uses for
The art normal test conditions；Unless stated otherwise, agents useful for same is purchased in market in the present invention.
Embodiment 1
A kind of bacteriostatic gel for treating vulval dermatitis itch, the weight proportion of material composition are as follows：
3 parts of frutus cnidii, 8 parts of folium artemisiae argyi, 9 parts of honeysuckle, 4 parts of cordate houttuynia, 5 parts of the tuber of stemona, 2 parts of angelica tail, 4 parts of garden burnet, floats at 4 parts of kuh-seng
1 part of duckweed, 5 parts of the root of Chinese clematis, 1 part of coptis root, 3 parts of Radix Angelicae Pubescentis, 20 parts of castor oil, 4 parts of acetic acid chlorhexidine.
A kind of bacteriostatic gel preparation method for treating vulval dermatitis itch, includes the following steps：
（1）Chinese medicine material is ground into fine powder with pulverizer, the purified water that 20 times of amounts of medicinal material total weight are added decocts 2-3h, mistake
Filtrate is collected in filter；The water that 8-15 times of medicinal material weight is measured is added in the dregs of a decoction again and decocts 1-2h, filtering collects filtrate, by two
Secondary filtrate merges, and is concentrated into the medicinal extract of semisolid；
（2）Medicinal extract is freeze-dried, 200 mesh sieve is crushed, obtains Chinese medicinal powder；
（3）1.5 are pressed in 75% ethyl alcohol:1 takes acetic acid chlorhexidine to be mixed with Chinese medicinal powder, is heated in 70~80 DEG C of water-baths, melts
Change, stir evenly, after fully emulsified, stirring and gradually cooling stir evenly, and obtain clear gel, as this product.
Embodiment 2
A kind of bacteriostatic gel for treating vulval dermatitis itch, the weight proportion of material composition are as follows：
4 parts of frutus cnidii, 10 parts of folium artemisiae argyi, 7 parts of honeysuckle, 5 parts of cordate houttuynia, 3 parts of the tuber of stemona, 5 parts of angelica tail, 2 parts of garden burnet, floats at 2 parts of kuh-seng
3 parts of duckweed, 4 parts of the root of Chinese clematis, 3 parts of coptis root, 2 parts of Radix Angelicae Pubescentis, 30 parts of castor oil, 3 parts of acetic acid chlorhexidine.
A kind of bacteriostatic gel preparation method for treating vulval dermatitis itch, includes the following steps：
（1）Chinese medicine material is ground into fine powder with pulverizer, the purified water that 20 times of amounts of medicinal material total weight are added decocts 2-3h, mistake
Filtrate is collected in filter；The water that 8-15 times of medicinal material weight is measured is added in the dregs of a decoction again and decocts 1-2h, filtering collects filtrate, by two
Secondary filtrate merges, and is concentrated into the medicinal extract of semisolid；
（2）Medicinal extract is freeze-dried, 200 mesh sieve is crushed, obtains Chinese medicinal powder；
（3）1.5 are pressed in 75% ethyl alcohol:1 takes acetic acid chlorhexidine to be mixed with Chinese medicinal powder, is heated in 70~80 DEG C of water-baths, melts
Change, stir evenly, after fully emulsified, stirring and gradually cooling stir evenly, and obtain clear gel, as this product.
Embodiment 3
A kind of bacteriostatic gel for treating vulval dermatitis itch, the weight proportion of material composition are as follows：
5 parts of frutus cnidii, 9 parts of folium artemisiae argyi, 8 parts of honeysuckle, 4 parts of cordate houttuynia, 4- parts of the tuber of stemona, 4 parts of angelica tail, 3 parts of garden burnet, floats at 3 parts of kuh-seng
3 parts of duckweed, 3 parts of the root of Chinese clematis, 3 parts of coptis root, 2 parts of Radix Angelicae Pubescentis, 35 parts of castor oil, 2 parts of acetic acid chlorhexidine.
A kind of bacteriostatic gel preparation method for treating vulval dermatitis itch, includes the following steps：
（1）Chinese medicine material is ground into fine powder with pulverizer, the purified water that 20 times of amounts of medicinal material total weight are added decocts 2-3h, mistake
Filtrate is collected in filter；The water that 8-15 times of medicinal material weight is measured is added in the dregs of a decoction again and decocts 1-2h, filtering collects filtrate, by two
Secondary filtrate merges, and is concentrated into the medicinal extract of semisolid；
（2）Medicinal extract is freeze-dried, 200 mesh sieve is crushed, obtains Chinese medicinal powder；
（3）1.5 are pressed in 75% ethyl alcohol:1 takes acetic acid chlorhexidine to be mixed with Chinese medicinal powder, is heated in 70~80 DEG C of water-baths, melts
Change, stir evenly, after fully emulsified, stirring and gradually cooling stir evenly, and obtain clear gel, as this product.
Model case：
1. Luo, female, 26 years old, Hubei people from Wuhan.Symptom：Patient's vulva itch repeatedly over 2 years, when be often accompanied by burning heat sensation, have Huang
White mutually miscellaneous secretion, flow is more, there is bad smell, once with metronidazole is oral and intravaginal treatment, improves after treatment, but answer soon
Hair.Sick age：3 years.Therapy：Vulva is first wiped with warm water, then this appropriate gel is taken to be applied at vulva, twice a day；Make
With second day, patient's pruritus vulvue symptom was substantially reduced；Using 5 days, do not occur pruritus vulvue symptom again；Adhere to using 10 days,
After stopping using, do not recur again.
2. Sun, female, 34 years old, Hubei people from Wuhan.Symptom：Before 8 months, there is pruritus vulvue in patient, and night symptom is aggravated,
Often itch to be unable to bear and goes to grab with hand, it usually can not good sleep.Once oral traditional Chinese medicine is attempted, or smears hormonal drug for a long time
Fail to cure.Sick age：8 months.Therapy：Vulva is first wiped with warm water, then this appropriate gel is taken to be applied at vulva, daily
Once；Using 3 days, symptom thoroughly disappeared；Adhere to using 6 days, be discontinued so far without recurrence.
3. Zhao, female, 42 years old, Hubei people from Wuhan.Symptom：Nearly 4 years of patient's pruritus vulvue, the aggravation of pruritus vulvue symptom, outside
The moon is usually very itched unbearably, and the pain increased after scratching.Vulvar disease pachyderma has pleat like leather protuberance, and eczema occurs
Sample changes, and surface color is dark red.Therapy：Vulva is first wiped with warm water, then this appropriate gel is taken to be applied at vulva, daily
It is secondary；Using 5 days, pruritis was relieved；Using 11 days, in addition to still there is slight pruritis at night, daytime was no longer
There is pruritus vulvue symptom；Using 18 days, pruritis completely disappeared；It continues to strengthen and uses 5 days, be discontinued so far without recurrence, make
Do not occur any side effect with period.
The above is only the application implementation mode of the present invention, it is noted that for the ordinary skill people of the art
For member, without departing from the technical principles of the invention, several improvements and modifications can also be made, these improvements and modifications
Also it should be regarded as protection scope of the present invention.
Claims (8)
1. a kind of bacteriostatic gel for treating vulval dermatitis itch, which is characterized in that the parts by weight of each component are：
3-6 parts of dittany bark, 2-5 parts of the fruit of summer cypress, 1-4 parts of kuh-seng, 1-4 parts of frutus cnidii, 1-4 parts of the tuber of stemona, 2-5 parts of rheum officinale, peppermint 2-5
Part, 20-40 parts of castor oil, 1-4 parts of acetic acid chlorhexidine.
2. a kind of bacteriostatic gel for treating vulval dermatitis itch, which is characterized in that the parts by weight of each component are：
5-6 parts of dittany bark, 2-3 parts of the fruit of summer cypress, 3-4 parts of kuh-seng, 1-2 parts of frutus cnidii, 3-4 parts of the tuber of stemona, 2-4 parts of rheum officinale, peppermint 3-5
Part, 20-30 parts of castor oil, 1-2 parts of acetic acid chlorhexidine.
3. a kind of bacteriostatic gel for treating vulval dermatitis itch, which is characterized in that the parts by weight of each component are：
3-4 parts of dittany bark, 4-5 parts of the fruit of summer cypress, 1-3 parts of kuh-seng, 3-4 parts of frutus cnidii, 1-3 parts of the tuber of stemona, 4-5 parts of rheum officinale, peppermint 2-3
Part, 30-40 parts of castor oil, 3-4 parts of acetic acid chlorhexidine.
4. a kind of bacteriostatic gel for treating vulval dermatitis itch, which is characterized in that the parts by weight of each component are：
4-6 parts of dittany bark, 3-5 parts of the fruit of summer cypress, 2-3 parts of kuh-seng, 2-3 parts of frutus cnidii, 2-4 parts of the tuber of stemona, 3-4 parts of rheum officinale, peppermint 4-5
Part, 25-35 parts of castor oil, 2-4 parts of acetic acid chlorhexidine.
5. a kind of bacteriostatic gel for treating vulval dermatitis itch, it is characterised in that the bacteriostatic gel is usually at one month or so
It takes effect, can cure within 1~6 month；Antipruritic effect is good, controls difficulty in relapse after healing, has no toxic side effect.
6. a kind of antibacterial aqua preparation method for treating dermatitis, eczema, pruigo, includes the following steps：
（1）Chinese medicine material is ground into fine powder with pulverizer, the purified water that 20 times of amounts of medicinal material total weight are added decocts 2-3h, mistake
Filtrate is collected in filter；The water that 8-15 times of medicinal material weight is measured is added in the dregs of a decoction again and decocts 1-2h, filtering collects filtrate, by two
Secondary filtrate merges, and is concentrated into the medicinal extract of semisolid；
（2）Medicinal extract is freeze-dried, 200 mesh sieve is crushed, obtains Chinese medicinal powder；
（3）1.5 are pressed in 75% ethyl alcohol:1 takes acetic acid chlorhexidine to be mixed with Chinese medicinal powder, is heated in 70~80 DEG C of water-baths, melts
Change, stir evenly, after fully emulsified, stirring and gradually cooling stir evenly, and obtain clear gel, as this product.
7. according to the method described in claim 6, it is characterized in that：Add Western medicine acetic acid chlorhexidine and various Chinese medicines mixing and
At.
8. according to the method described in claim 6, it is characterized in that：Acetic acid chlorhexidine is dissolved with 75% ethyl alcohol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810535981.8A CN108553608A (en) | 2018-05-30 | 2018-05-30 | A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810535981.8A CN108553608A (en) | 2018-05-30 | 2018-05-30 | A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108553608A true CN108553608A (en) | 2018-09-21 |
Family
ID=63552366
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810535981.8A Withdrawn CN108553608A (en) | 2018-05-30 | 2018-05-30 | A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108553608A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109589372A (en) * | 2019-01-02 | 2019-04-09 | 江西乾坤堂健康科技有限公司 | A kind of compound book on Chinese herbal medicine antibacterial liquid and preparation method thereof |
| CN113679771A (en) * | 2021-10-14 | 2021-11-23 | 浙江养和健康管理科技有限公司 | Traditional Chinese medicine composition for treating dermatitis and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1483408A (en) * | 2003-07-30 | 2004-03-24 | 童玉新 | Kecuocryptone gel and preparation process thereof |
| CN1943666A (en) * | 2005-10-08 | 2007-04-11 | 曾雄辉 | A Chinese/western compound medicine for treatment of and preventing women's colpitis |
| CN101161259A (en) * | 2006-10-13 | 2008-04-16 | 朱圣华 | A Chinese medicine lotion for preventing and controlling male and female pudendum disease |
| CN102755577A (en) * | 2012-07-24 | 2012-10-31 | 周堃 | Traditional Chinese medicine lotion for treating pruritus vulvae |
-
2018
- 2018-05-30 CN CN201810535981.8A patent/CN108553608A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1483408A (en) * | 2003-07-30 | 2004-03-24 | 童玉新 | Kecuocryptone gel and preparation process thereof |
| CN1943666A (en) * | 2005-10-08 | 2007-04-11 | 曾雄辉 | A Chinese/western compound medicine for treatment of and preventing women's colpitis |
| CN101161259A (en) * | 2006-10-13 | 2008-04-16 | 朱圣华 | A Chinese medicine lotion for preventing and controlling male and female pudendum disease |
| CN102755577A (en) * | 2012-07-24 | 2012-10-31 | 周堃 | Traditional Chinese medicine lotion for treating pruritus vulvae |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109589372A (en) * | 2019-01-02 | 2019-04-09 | 江西乾坤堂健康科技有限公司 | A kind of compound book on Chinese herbal medicine antibacterial liquid and preparation method thereof |
| CN113679771A (en) * | 2021-10-14 | 2021-11-23 | 浙江养和健康管理科技有限公司 | Traditional Chinese medicine composition for treating dermatitis and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102406761B (en) | Traditional Chinese medicine oil for treating burn, scald or acute and chronic ulcer sore surface and preparation method thereof | |
| CN101199787B (en) | Medicament compound for treating skin disease | |
| CN103933443A (en) | Itching-relieving washing medicine bag and preparation method thereof | |
| CN1879831A (en) | Bacteriostatic externally applied preparation for treating gynecological inflammation and method for preparing same | |
| CN103007124B (en) | Chinese medicine preparation for treating gynecologic inflammation | |
| CN103316262B (en) | A kind of gynecological external antibacterial liquid and preparation method thereof | |
| CN103263525B (en) | Gynecological cleaning fluid and preparation method thereof | |
| CN101485766A (en) | Chinese medicine washing lotion for treating colpitis and preparation method thereof | |
| CN108553608A (en) | A kind of bacteriostatic gel and preparation method thereof for treating vulval dermatitis itch | |
| CN101485810A (en) | External-use lotion for treating gynaecological inflammation and preparation method thereof | |
| CN103191355B (en) | Traditional Chinese medicine preparation for treating pruritus vulvae and preparation method of traditional Chinese medicine preparation | |
| CN103463284B (en) | Gynecological cleaning liquid and preparation method thereof | |
| CN101647974B (en) | Traditional Chinese medicine for treating summer carbuncle and ulcerative carbuncle and preparation method thereof | |
| CN102671084A (en) | Medicine of male genital organ cleaning lotion and preparation method thereof | |
| CN102755577B (en) | Traditional Chinese medicine lotion for treating pruritus vulvae | |
| CN1125599A (en) | Composition of external-use medicine for improving skin and gynecology and its manufacture method | |
| CN102670976B (en) | Heath-care gynecological lotion | |
| CN108904749B (en) | Granulation promoting and growing paste and preparation method thereof | |
| CN111743982A (en) | Vulva lotion and preparation method thereof | |
| KR100769304B1 (en) | Herb medicine composition to be contained in wet paper for infants | |
| CN105412458A (en) | Bacteriostatic lotion for female care | |
| CN102091273B (en) | Gynecological lotion and preparation method thereof | |
| KR20170021493A (en) | The water containing tissue having the excellent effect of prophylaxis and treatment against skin ailments | |
| CN110664861A (en) | Medicine composition for treating vulvitis | |
| CN111110941A (en) | Gynecological nursing method and auxiliary nursing equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180921 |